BR112012020596A8 - substrato para a imobilização de substâncias funcionais e processo para preparar o mesmo. - Google Patents

substrato para a imobilização de substâncias funcionais e processo para preparar o mesmo.

Info

Publication number
BR112012020596A8
BR112012020596A8 BR112012020596A BR112012020596A BR112012020596A8 BR 112012020596 A8 BR112012020596 A8 BR 112012020596A8 BR 112012020596 A BR112012020596 A BR 112012020596A BR 112012020596 A BR112012020596 A BR 112012020596A BR 112012020596 A8 BR112012020596 A8 BR 112012020596A8
Authority
BR
Brazil
Prior art keywords
substrate
immobilization
preparing
radical
same
Prior art date
Application number
BR112012020596A
Other languages
English (en)
Other versions
BR112012020596A2 (pt
BR112012020596B1 (pt
Inventor
Gert Bluchel Christian
Original Assignee
Temasek Polytechnic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temasek Polytechnic filed Critical Temasek Polytechnic
Publication of BR112012020596A2 publication Critical patent/BR112012020596A2/pt
Publication of BR112012020596A8 publication Critical patent/BR112012020596A8/pt
Publication of BR112012020596B1 publication Critical patent/BR112012020596B1/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • C12N11/12—Cellulose or derivatives thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/243—Dialysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/08—Polysaccharides
    • B01D71/12—Cellulose derivatives
    • B01D71/14—Esters of organic acids
    • B01D71/16—Cellulose acetate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/321—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3202—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the carrier, support or substrate used for impregnation or coating
    • B01J20/3206—Organic carriers, supports or substrates
    • B01J20/3208—Polymeric carriers, supports or substrates
    • B01J20/3212—Polymeric carriers, supports or substrates consisting of a polymer obtained by reactions otherwise than involving only carbon to carbon unsaturated bonds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • B01J20/3248—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such
    • B01J20/3251—Non-macromolecular compounds having a well defined chemical structure the functional group or the linking, spacer or anchoring group as a whole comprising at least one type of heteroatom selected from a nitrogen, oxygen or sulfur, these atoms not being part of the carrier as such comprising at least two different types of heteroatoms selected from nitrogen, oxygen or sulphur
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Transplantation (AREA)
  • Water Supply & Treatment (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)

Abstract

substrato para a imobilização de substâncias funcionais e método para preparação do mesmo a presente invenção se refere a um substrato com compostos nele dispostos para a imobilização de uma molécula funcional, cada composto tendo uma cadeia compreendendo: um radical r que é quimicamente acoplado as substrato, o radical r sendo selecionado a partir do grupo consistindo de um éter, éster, carbonila, éster, de carbonato, tioéter, dissulfeto, sulfinila, sulfonila, e carbonotioila; e um radical contendo epóxido que é acoplado ao radical r por um ligante compreendendo de pelo menos um grupo nucleofilico. métodos de preparação do substrato e utilização do substrato são também descritos.
BR112012020596-0A 2010-02-19 2011-02-18 Substrato sólido; método de imobilização de uma molécula funcional; método de modificação de uma membrana de diálise; método de preparação de um substrato sólido; cartucho absorvente para uso em um dispositivo de diálise; e dializador para uso em um dispositivo de diálise BR112012020596B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1002824.9A GB201002824D0 (en) 2010-02-19 2010-02-19 A method of preparing a substrate for immobilization of functional substances thereon and the substrate obtained therefrom
GB1002824.9 2010-02-19
PCT/SG2011/000069 WO2011102807A1 (en) 2010-02-19 2011-02-18 A substrate for immobilizing functional substances and method for preparing the same

Publications (3)

Publication Number Publication Date
BR112012020596A2 BR112012020596A2 (pt) 2018-03-13
BR112012020596A8 true BR112012020596A8 (pt) 2020-09-01
BR112012020596B1 BR112012020596B1 (pt) 2021-06-15

Family

ID=42114062

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012020596-0A BR112012020596B1 (pt) 2010-02-19 2011-02-18 Substrato sólido; método de imobilização de uma molécula funcional; método de modificação de uma membrana de diálise; método de preparação de um substrato sólido; cartucho absorvente para uso em um dispositivo de diálise; e dializador para uso em um dispositivo de diálise

Country Status (12)

Country Link
US (3) US8440441B2 (pt)
EP (1) EP2536485B1 (pt)
JP (1) JP6006121B2 (pt)
CN (1) CN102858437B (pt)
AU (1) AU2011218501B2 (pt)
BR (1) BR112012020596B1 (pt)
ES (1) ES2816224T3 (pt)
GB (1) GB201002824D0 (pt)
NZ (1) NZ601859A (pt)
RU (1) RU2602901C2 (pt)
SG (1) SG183292A1 (pt)
WO (1) WO2011102807A1 (pt)

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US9481879B2 (en) * 2012-06-26 2016-11-01 Avent, Inc. Preparation of stabilized catalase enzymes with a surfactant
EP2792688B1 (en) 2013-04-15 2015-06-10 King Saud University Amine grafted chitosan nanofiber, method for preparation thereof and its use in heavy metal adsorption
CN104753618B (zh) * 2013-12-31 2017-07-28 华为技术有限公司 一种无线信道建模方法及设备
CN105980485B (zh) * 2014-02-04 2018-11-27 巴斯夫欧洲公司 使用特定的蒽醌染料配体结构来纯化抗体、抗体片段或其工程变体的方法
JP6503734B2 (ja) * 2014-12-26 2019-04-24 ソニー株式会社 情報処理装置、制御方法、およびプログラム
JP6874390B2 (ja) * 2016-01-29 2021-05-19 東レ株式会社 改質セルロース
US11458235B2 (en) 2016-12-05 2022-10-04 Temasek Polytechnic Sorbent for a dialysis device and dialysis system
SE540480C2 (en) * 2017-02-15 2018-09-25 Pharem Biotech Ab Enzymatic purification of water
CN107185418A (zh) * 2017-06-13 2017-09-22 江南大学 一种正电性血液透析膜及其制备方法
WO2019110557A1 (en) 2017-12-04 2019-06-13 Stichting Voor De Technische Wetenschappen Macromolecular compositions comprising indene-derivatives, preparation thereof, and use thereof
US11572417B2 (en) 2019-05-08 2023-02-07 University Of Rhode Island Board Of Trustees Surface functionalization of cellulose and other substrates
WO2021099577A1 (en) 2019-11-22 2021-05-27 Stichting Voor De Technische Wetenschappen Macromolecular compositions for binding small molecules
US20220401889A1 (en) 2019-11-22 2022-12-22 Stichting Voor De Technische Wetenschappen Porous membranes comprising sorbent particles for improved urea capture
CN111560408B (zh) * 2020-02-29 2022-11-25 浙江工业大学 一种基于流动化学酶促在线合成香豆素-3-羧酸糖酯衍生物的方法
CN111773933B (zh) * 2020-06-28 2022-06-24 健帆生物科技集团股份有限公司 聚乳酸透析膜及其制备方法、透析器
CN111871396A (zh) * 2020-08-03 2020-11-03 中国科学院过程工程研究所 一种白蛋白静电亲和双模式层析介质及其制备方法和应用
CN112679701B (zh) * 2020-12-28 2022-02-25 重庆宸安生物制药有限公司 一种固定化赖氨酸内肽酶及其制备方法与用途
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CN113914094B (zh) * 2021-10-13 2023-12-22 江苏大学 一种碳酸钙/聚合物纳米纤维复合膜的制备方法
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Also Published As

Publication number Publication date
AU2011218501B2 (en) 2014-10-23
BR112012020596A2 (pt) 2018-03-13
AU2011218501A1 (en) 2012-09-06
US20130210111A1 (en) 2013-08-15
ES2816224T3 (es) 2021-03-31
EP2536485A4 (en) 2013-08-28
US20140017761A1 (en) 2014-01-16
GB201002824D0 (en) 2010-04-07
US8561811B2 (en) 2013-10-22
EP2536485A1 (en) 2012-12-26
US8440441B2 (en) 2013-05-14
SG183292A1 (en) 2012-09-27
BR112012020596B1 (pt) 2021-06-15
JP2013520226A (ja) 2013-06-06
CN102858437B (zh) 2016-02-10
RU2012140038A (ru) 2014-03-27
RU2602901C2 (ru) 2016-11-20
JP6006121B2 (ja) 2016-10-12
WO2011102807A1 (en) 2011-08-25
EP2536485B1 (en) 2020-07-15
US20130048559A1 (en) 2013-02-28
NZ601859A (en) 2014-12-24
CN102858437A (zh) 2013-01-02

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06T Formal requirements before examination [chapter 6.20 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
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