BRPI0917144A2 - Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto. - Google Patents

Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto.

Info

Publication number
BRPI0917144A2
BRPI0917144A2 BRPI0917144-4A BRPI0917144A BRPI0917144A2 BR PI0917144 A2 BRPI0917144 A2 BR PI0917144A2 BR PI0917144 A BRPI0917144 A BR PI0917144A BR PI0917144 A2 BRPI0917144 A2 BR PI0917144A2
Authority
BR
Brazil
Prior art keywords
preparing
epepa
dbta
dpta
phenylethyl
Prior art date
Application number
BRPI0917144-4A
Other languages
English (en)
Inventor
Taiju Nakamura
Masaaki Matsuda
Yongbo Hu
Daiju Hasegawa
Yorihisa Hoshino
Kazato Inanaga
Minetaka Isomura
Nobuaki Sato
Kazuhiro Yoshizawa
George A Moniz
Gordon D Wilkie
Francis G Fang
Yoshihiro Nishikawa
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Publication of BRPI0917144A2 publication Critical patent/BRPI0917144A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/04—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers
    • C07C257/06—Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines without replacement of the other oxygen atom of the carboxyl group, e.g. imino-ethers having carbon atoms of imino-carboxyl groups bound to hydrogen atoms, to acyclic carbon atoms, or to carbon atoms of rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0917144-4A 2008-08-27 2009-08-26 Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto. BRPI0917144A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9226208P 2008-08-27 2008-08-27
PCT/US2009/055079 WO2010025197A1 (en) 2008-08-27 2009-08-26 Process for preparing certain cinnamide compounds

Publications (1)

Publication Number Publication Date
BRPI0917144A2 true BRPI0917144A2 (pt) 2015-08-04

Family

ID=41228418

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0917144-4A BRPI0917144A2 (pt) 2008-08-27 2009-08-26 Processo para preparar compostos, processo para preparar uma mistura, sais de d-dbta, de d-dpta e de ácido (+) -n- (1-feniletila) ftalâmico ((+) -pepa), e, composto.

Country Status (10)

Country Link
US (1) US20110172427A1 (pt)
EP (1) EP2324009A1 (pt)
JP (1) JP2012501336A (pt)
CN (1) CN102137855A (pt)
BR (1) BRPI0917144A2 (pt)
CA (1) CA2733606A1 (pt)
IL (1) IL211166A0 (pt)
MX (1) MX2011002002A (pt)
RU (1) RU2011111534A (pt)
WO (1) WO2010025197A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101815713B (zh) 2007-08-31 2013-09-11 卫材R&D管理有限公司 多环化合物
AU2010218667A1 (en) * 2009-02-26 2011-07-21 Eisai R&D Management Co., Ltd. Salt of tetrahydrotriazolopyridine derivative and crystal thereof
MX2011008501A (es) 2009-02-26 2011-09-01 Eisai R&D Man Co Ltd Compuestos heterociclicos fusionados que contienen nitrogeno y su uso como inhibidores de la produccion de beta-amiloide.
ES2602794T3 (es) 2011-03-31 2017-02-22 Pfizer Inc Piridinonas bicíclicas novedosas
UA110688C2 (uk) 2012-09-21 2016-01-25 Пфайзер Інк. Біциклічні піридинони
KR102000382B1 (ko) 2015-02-03 2019-07-15 화이자 인코포레이티드 신규 시클로프로파벤조푸라닐 피리도피라진디온

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1781624A4 (en) * 2004-07-02 2010-06-23 Taro Pharma Ind PROCESS FOR THE PREPARATION OF 1-METHOXYMETHYL-5,5-DIPHENYLBARBITURIC ACID
GEP20115139B (en) * 2006-03-09 2011-01-10 Eisai R&D Man Co Ltd Polycyclic cinnamide derivative
US7935815B2 (en) * 2007-08-31 2011-05-03 Eisai R&D Management Co., Ltd. Imidazoyl pyridine compounds and salts thereof
CN101815713B (zh) * 2007-08-31 2013-09-11 卫材R&D管理有限公司 多环化合物

Also Published As

Publication number Publication date
MX2011002002A (es) 2011-03-29
EP2324009A1 (en) 2011-05-25
WO2010025197A1 (en) 2010-03-04
RU2011111534A (ru) 2012-10-10
US20110172427A1 (en) 2011-07-14
JP2012501336A (ja) 2012-01-19
IL211166A0 (en) 2011-04-28
CN102137855A (zh) 2011-07-27
CA2733606A1 (en) 2010-03-04

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.