BRPI1007654A2 - composto, processo para a obtenção de um composto de fórmula geral e composição farmacêutica - Google Patents
composto, processo para a obtenção de um composto de fórmula geral e composição farmacêuticaInfo
- Publication number
- BRPI1007654A2 BRPI1007654A2 BRPI1007654A BRPI1007654A BRPI1007654A2 BR PI1007654 A2 BRPI1007654 A2 BR PI1007654A2 BR PI1007654 A BRPI1007654 A BR PI1007654A BR PI1007654 A BRPI1007654 A BR PI1007654A BR PI1007654 A2 BRPI1007654 A2 BR PI1007654A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- obtaining
- general formula
- pharmaceutical composition
- pharmaceutical
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 2
- 239000000203 mixture Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/655—Somatostatins
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ESP200901168 | 2009-05-07 | ||
| ES200901168A ES2351569B8 (es) | 2009-05-07 | 2009-05-07 | Ligandos peptídicos de receptores de somatostatina. |
| PCT/EP2010/056152 WO2010128098A1 (en) | 2009-05-07 | 2010-05-06 | Peptide ligands of somatostatin receptors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI1007654A2 true BRPI1007654A2 (pt) | 2016-02-23 |
| BRPI1007654B1 BRPI1007654B1 (pt) | 2022-05-03 |
Family
ID=42357876
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1007654-9A BRPI1007654B1 (pt) | 2009-05-07 | 2010-05-06 | Composto, processo para a obtenção de um composto de fórmula geral e composição farmacêutica |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8946154B2 (pt) |
| EP (1) | EP2427775B1 (pt) |
| JP (1) | JP6162952B2 (pt) |
| KR (1) | KR101592064B1 (pt) |
| CN (1) | CN102428371B (pt) |
| AU (1) | AU2010244439B2 (pt) |
| BR (1) | BRPI1007654B1 (pt) |
| CA (1) | CA2760977C (pt) |
| DK (1) | DK2427775T3 (pt) |
| ES (2) | ES2351569B8 (pt) |
| HU (1) | HUE056400T2 (pt) |
| IL (1) | IL216086A (pt) |
| MX (1) | MX2011011723A (pt) |
| PL (1) | PL2427775T3 (pt) |
| PT (1) | PT2427775T (pt) |
| RU (1) | RU2525468C2 (pt) |
| WO (1) | WO2010128098A1 (pt) |
| ZA (1) | ZA201108967B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104768565B (zh) * | 2012-11-01 | 2017-04-26 | 益普生制药股份有限公司 | 促生长素抑制素类似物及其二聚体 |
| PT3046933T (pt) * | 2013-09-18 | 2019-05-31 | Bcn Peptides Sa | Análogos de cortistatina para o tratamento de doenças inflamatórias e/ou imunitárias |
| CN104086630B (zh) * | 2014-06-25 | 2016-06-29 | 天津欧德莱生物医药科技有限公司 | 一种生长抑素受体激动剂多肽及其应用 |
| CN104045689B (zh) * | 2014-06-25 | 2016-08-24 | 新乡医学院 | 一种关于生长抑素受体激动剂多肽及其应用 |
| CN104045690B (zh) * | 2014-06-25 | 2016-06-08 | 舟山医院 | 生长抑素受体激动剂多肽及其应用 |
| CN107530435A (zh) | 2015-03-02 | 2018-01-02 | 科赛普特治疗学股份有限公司 | 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤 |
| CN110475558A (zh) | 2017-03-09 | 2019-11-19 | 科赛普特治疗学股份有限公司 | 糖皮质激素受体调节剂在儿茶酚胺分泌型肿瘤治疗中的应用 |
| EP3684794A1 (en) | 2017-09-19 | 2020-07-29 | Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. | Somatostatin prodrugs |
| ES2780274A1 (es) | 2019-02-15 | 2020-08-24 | Consejo Superior De Investig Científicas (Csic) | Cortistatina o un análogo de la misma como agente farmacéuticamente activo en forma latente |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3904594A (en) * | 1973-07-02 | 1975-09-09 | Salk Inst For Biological Studi | Somatostatin and acylated des-(ala' 1', gly' 2') derivatives thereof |
| SU586837A3 (ru) * | 1973-12-10 | 1977-12-30 | Ауэрст, Маккенна Энд Харрисон Лимитед (Фирма) | Способ получени производных соматостатина |
| US4133782A (en) | 1976-06-07 | 1979-01-09 | The Salk Institute For Biological Studies | Somatostatin analogs with dissociated biological activities |
| US4211693A (en) * | 1977-09-20 | 1980-07-08 | The Salk Institute For Biological Studies | Peptides with para-substituted phenylalanine |
| US5364851A (en) * | 1991-06-14 | 1994-11-15 | International Synthecon, Llc | Conformationally restricted biologically active peptides, methods for their production and uses thereof |
| US5932189A (en) * | 1994-07-29 | 1999-08-03 | Diatech, Inc. | Cyclic peptide somatostatin analogs |
| US5750499A (en) * | 1995-10-18 | 1998-05-12 | The Salk Institute For Biological Studies | Receptor-selective somatostatin analogs |
| IT1283134B1 (it) * | 1996-07-08 | 1998-04-07 | Dox Al Italia Spa | Derivati sintetici e semisintetici di somatostatine utili nella stimolazione della crescita corporea, in particolare in |
| PL334089A1 (en) * | 1996-12-04 | 2000-01-31 | Sod Conseils Rech Applic | Compounds antagonistic in respect to somatostatin |
| US5968903A (en) * | 1998-05-07 | 1999-10-19 | Biomeasure, Incorporated | Inhibition of H. pylori proliferation |
| FR2819508B1 (fr) * | 2001-01-12 | 2005-01-21 | Sod Conseils Rech Applic | Derives de 2-arylimino-2, 3-dihydorthiazoles, leurs procedes de preparation et leur utilisation therapeutiques |
| US6358491B1 (en) * | 1999-08-27 | 2002-03-19 | Berlex Laboratories, Inc. | Somatostatin analogs |
| EP1283216A1 (en) | 2001-08-10 | 2003-02-12 | Mallinckrodt Inc. | Somatostatin analogues binding to all somatostatin receptor subtypes and their use |
| CN101336915B (zh) * | 2008-08-12 | 2010-12-22 | 沈阳斯佳科技发展有限公司 | 一种具有抗肿瘤活性的药物组合物 |
-
2009
- 2009-05-07 ES ES200901168A patent/ES2351569B8/es active Active
-
2010
- 2010-05-06 EP EP10718582.9A patent/EP2427775B1/en active Active
- 2010-05-06 RU RU2011146931/04A patent/RU2525468C2/ru active
- 2010-05-06 CN CN201080019851.0A patent/CN102428371B/zh active Active
- 2010-05-06 MX MX2011011723A patent/MX2011011723A/es active IP Right Grant
- 2010-05-06 BR BRPI1007654-9A patent/BRPI1007654B1/pt not_active IP Right Cessation
- 2010-05-06 PT PT107185829T patent/PT2427775T/pt unknown
- 2010-05-06 DK DK10718582.9T patent/DK2427775T3/da active
- 2010-05-06 PL PL10718582T patent/PL2427775T3/pl unknown
- 2010-05-06 AU AU2010244439A patent/AU2010244439B2/en not_active Ceased
- 2010-05-06 US US13/319,285 patent/US8946154B2/en active Active
- 2010-05-06 WO PCT/EP2010/056152 patent/WO2010128098A1/en active Application Filing
- 2010-05-06 CA CA2760977A patent/CA2760977C/en active Active
- 2010-05-06 HU HUE10718582A patent/HUE056400T2/hu unknown
- 2010-05-06 KR KR1020117029096A patent/KR101592064B1/ko active IP Right Grant
- 2010-05-06 ES ES10718582T patent/ES2897566T3/es active Active
- 2010-05-06 JP JP2012509037A patent/JP6162952B2/ja active Active
-
2011
- 2011-11-01 IL IL216086A patent/IL216086A/en active IP Right Grant
- 2011-12-06 ZA ZA2011/08967A patent/ZA201108967B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2897566T3 (es) | 2022-03-01 |
| JP6162952B2 (ja) | 2017-07-12 |
| KR101592064B1 (ko) | 2016-02-18 |
| CA2760977A1 (en) | 2010-11-11 |
| CA2760977C (en) | 2016-04-26 |
| ES2351569A1 (es) | 2011-02-08 |
| HUE056400T2 (hu) | 2022-02-28 |
| PT2427775T (pt) | 2021-11-12 |
| EP2427775B1 (en) | 2021-08-11 |
| IL216086A (en) | 2017-11-30 |
| AU2010244439B2 (en) | 2013-10-03 |
| RU2525468C2 (ru) | 2014-08-20 |
| JP2012526081A (ja) | 2012-10-25 |
| CN102428371A (zh) | 2012-04-25 |
| US20120122781A1 (en) | 2012-05-17 |
| WO2010128098A1 (en) | 2010-11-11 |
| AU2010244439A1 (en) | 2011-11-10 |
| EP2427775A1 (en) | 2012-03-14 |
| MX2011011723A (es) | 2012-02-28 |
| ES2351569B1 (es) | 2011-12-05 |
| CN102428371B (zh) | 2015-08-12 |
| KR20120027302A (ko) | 2012-03-21 |
| ZA201108967B (en) | 2012-08-29 |
| US8946154B2 (en) | 2015-02-03 |
| IL216086A0 (en) | 2012-01-31 |
| BRPI1007654B1 (pt) | 2022-05-03 |
| DK2427775T3 (da) | 2021-11-08 |
| ES2351569B8 (es) | 2012-06-20 |
| PL2427775T3 (pl) | 2022-01-17 |
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