BRPI0910545A2 - processo contínuo para fazer composições farmacêuticas - Google Patents

processo contínuo para fazer composições farmacêuticas

Info

Publication number
BRPI0910545A2
BRPI0910545A2 BRPI0910545A BRPI0910545A BRPI0910545A2 BR PI0910545 A2 BRPI0910545 A2 BR PI0910545A2 BR PI0910545 A BRPI0910545 A BR PI0910545A BR PI0910545 A BRPI0910545 A BR PI0910545A BR PI0910545 A2 BRPI0910545 A2 BR PI0910545A2
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
continuous process
making pharmaceutical
making
continuous
Prior art date
Application number
BRPI0910545A
Other languages
English (en)
Inventor
Abut T M Serajuddin
James Kowalski
Jay Parthiban Lakshman
Madhav Vasathavada
Wei-Qin Tong
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BRPI0910545A2 publication Critical patent/BRPI0910545A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/20—Extrusion means, e.g. for producing pharmaceutical forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
BRPI0910545A 2008-04-30 2009-04-29 processo contínuo para fazer composições farmacêuticas BRPI0910545A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4908808P 2008-04-30 2008-04-30
PCT/US2009/042050 WO2009134848A1 (en) 2008-04-30 2009-04-29 Continuous process for making pharmaceutical compositions

Publications (1)

Publication Number Publication Date
BRPI0910545A2 true BRPI0910545A2 (pt) 2015-09-29

Family

ID=40886918

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0910545A BRPI0910545A2 (pt) 2008-04-30 2009-04-29 processo contínuo para fazer composições farmacêuticas

Country Status (11)

Country Link
US (1) US20110037185A1 (pt)
EP (1) EP2280681A1 (pt)
JP (1) JP2011519610A (pt)
KR (1) KR20110003383A (pt)
CN (1) CN102014846A (pt)
AU (1) AU2009243139A1 (pt)
BR (1) BRPI0910545A2 (pt)
CA (1) CA2723053A1 (pt)
MX (1) MX2010011962A (pt)
RU (1) RU2010148536A (pt)
WO (1) WO2009134848A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9713575B2 (en) 2009-05-07 2017-07-25 Gea Process Engineering Limited Tablet production module and method for continuous production of tablets
KR101734948B1 (ko) 2009-10-09 2017-05-12 삼성전자주식회사 파워 헤드룸 보고, 자원 할당 및 전력 제어 방법
RU2015140628A (ru) 2010-11-04 2018-12-26 Эббви Инк. Способ изготовления монолитных таблеток
KR102125024B1 (ko) * 2013-06-27 2020-06-22 게아 프로세스 엔지니어링 엔브이 정제의 연속 제조 방법, 그러한 방법을 실시하기 위한 정제화 시스템, 및 입자 크기가 상당히 다른 입자들을 함유하는 적어도 2개의 원료들로 된 정제를 제조하기 위한 정제화 시스템의 용도
JP6636528B2 (ja) 2015-01-29 2020-01-29 インターコンチネンタル グレート ブランズ エルエルシー 食用組成物中の１種又はそれ以上の有効成分の送達システムを調製するための方法
FR3037789A1 (fr) * 2015-06-23 2016-12-30 Rondol Ind Ligne de production pour la production de medicaments, et installation de production comprenant une telle ligne de production
CN106539689B (zh) * 2015-09-18 2020-05-22 天士力医药集团股份有限公司 一种连续性的液体凝固的智能滴丸机
CN106860016A (zh) * 2017-02-08 2017-06-20 翰林航宇（天津）实业有限公司 一种胶囊制备一体机
EP3582741B1 (en) * 2017-02-17 2023-07-26 Massachusetts Institute of Technology Systems and methods for the fabrication of tablets, including pharmaceutical tablets
BR112020004952A2 (pt) * 2017-09-18 2020-09-15 Ferring International Center S.A. fabricação de composições farmacêuticas
CN108042363B (zh) * 2018-01-17 2020-07-31 陶俊荣 一种可在线检测中成药片剂制备系统和方法
DE102018010063A1 (de) 2018-03-16 2019-09-19 Ludwig-Maximilians-Universität München Herstellung vesikulärer Phospholipid-Gele durch Schnecken-Extrusion
CN109674656A (zh) * 2019-01-15 2019-04-26 苏州璞佩珊科技有限公司 一种制备药物制剂的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
HUP9900730A3 (en) * 1995-11-23 2001-04-28 Janssen Pharmaceutica Nv Solid mixtures of cyclodextrins prepared via melt-extrusion
DE19721467A1 (de) * 1997-05-22 1998-11-26 Basf Ag Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe
US6499984B1 (en) * 2000-05-22 2002-12-31 Warner-Lambert Company Continuous production of pharmaceutical granulation
ITRN20000051A1 (it) * 2000-12-22 2002-06-22 Ascor Chimici Srl Metodo e apparecchiatura per formare sferule composite contenenti principi attivi del tipo farmaceutico e/o integratori alimentari o cosmeti
EP1478345A4 (en) * 2002-01-03 2010-11-17 Glaxosmithkline Llc NOVEL PHARMACEUTICAL DOSAGE FORMS AND PROCESS FOR PRODUCTION OF SAID DOSAGE FORMS
SE0200154D0 (sv) * 2002-01-21 2002-01-21 Galenica Ab New process
WO2005000237A2 (en) * 2003-06-25 2005-01-06 University Of Tennessee Research Foundation Granules containing biologically active substances
GB0403098D0 (en) * 2004-02-12 2004-03-17 Euro Celtique Sa Extrusion
US20050238721A1 (en) * 2004-04-07 2005-10-27 Acquarulo Lawrence A Jr One step compounding extrusion of drug filled polymers
EP1881819A1 (en) * 2005-05-10 2008-01-30 Novartis AG Extrusion process for making compositions with poorly compressible therapeutic compounds
CN101166517B (zh) * 2005-05-10 2012-01-04 诺瓦提斯公司 制备含有可压性差的治疗性化合物的组合物的挤压方法
EP2015732A2 (en) * 2006-05-04 2009-01-21 Novartis AG Heated roller compaction process for making pharmaceutical compositions
US7771632B2 (en) * 2006-05-15 2010-08-10 American Leistritz Extruder Corp. Continuous melt spheronization apparatus and process for the production of pharmaceutical pellets
PT2054040E (pt) * 2006-08-16 2011-06-30 Novartis Ag Método para produzir dispersões sólidas de compostos terapêuticos altamente cristalinos

Also Published As

Publication number Publication date
AU2009243139A2 (en) 2010-11-18
MX2010011962A (es) 2010-11-30
EP2280681A1 (en) 2011-02-09
US20110037185A1 (en) 2011-02-17
KR20110003383A (ko) 2011-01-11
RU2010148536A (ru) 2012-06-10
JP2011519610A (ja) 2011-07-14
AU2009243139A1 (en) 2009-11-05
CN102014846A (zh) 2011-04-13
CA2723053A1 (en) 2009-11-05
WO2009134848A1 (en) 2009-11-05

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.