BR112017000304A2 - ?processos para a preparação dos compostos e para a purificação de um produto? - Google Patents

?processos para a preparação dos compostos e para a purificação de um produto?

Info

Publication number
BR112017000304A2
BR112017000304A2 BR112017000304A BR112017000304A BR112017000304A2 BR 112017000304 A2 BR112017000304 A2 BR 112017000304A2 BR 112017000304 A BR112017000304 A BR 112017000304A BR 112017000304 A BR112017000304 A BR 112017000304A BR 112017000304 A2 BR112017000304 A2 BR 112017000304A2
Authority
BR
Brazil
Prior art keywords
compounds
preparation
purification
processes
product
Prior art date
Application number
BR112017000304A
Other languages
English (en)
Other versions
BR112017000304B1 (pt
Inventor
Gebhardt Joachim
Ehresmann Manfred
Viertelhaus Martin
Goetz Roland
Chiodo Tiziana
Original Assignee
Basf Agro Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Agro Bv filed Critical Basf Agro Bv
Publication of BR112017000304A2 publication Critical patent/BR112017000304A2/pt
Publication of BR112017000304B1 publication Critical patent/BR112017000304B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

a presente invenção se refere a um processo para a preparação de compostos de oxirano de fórmula ii a partir de compostos ceto iii utilizando o sulfureto de dimetila (ch3)2s e sulfato de dimetila (ch3)2so4, formando o reagente iv, metilssulfato de trimetilssulfônio [(ch3)3s+ ch3so4-], em solução aquosa na presença de hidróxido de potássio (koh).
BR112017000304-0A 2014-07-08 2015-06-26 Processo para a preparação dos compostos de fórmula ii BR112017000304B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14176130 2014-07-08
EP14176130.4 2014-07-08
PCT/EP2015/064550 WO2016005211A1 (en) 2014-07-08 2015-06-26 Process for the preparation of substituted oxiranes and triazoles

Publications (2)

Publication Number Publication Date
BR112017000304A2 true BR112017000304A2 (pt) 2017-11-07
BR112017000304B1 BR112017000304B1 (pt) 2021-06-29

Family

ID=51063364

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017000304-0A BR112017000304B1 (pt) 2014-07-08 2015-06-26 Processo para a preparação dos compostos de fórmula ii

Country Status (10)

Country Link
US (1) US10053436B2 (pt)
EP (1) EP3166932B1 (pt)
CN (1) CN106660979B (pt)
BR (1) BR112017000304B1 (pt)
CA (1) CA2952896C (pt)
DK (1) DK3166932T3 (pt)
ES (1) ES2688377T3 (pt)
IL (1) IL249663B (pt)
MX (1) MX2017000317A (pt)
WO (1) WO2016005211A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2742288T3 (es) * 2013-01-09 2020-02-13 Basf Agro Bv Proceso para la preparación de oxiranos y triazoles sustituidos
EP3083540B1 (en) 2013-12-18 2019-11-20 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
EP3294720B1 (en) 2015-05-08 2020-12-02 BASF Agro B.V. A process for the preparation of terpinolene epoxide
DK3294700T3 (da) 2015-05-08 2020-04-14 Basf Agro Bv Fremgangsmåde til fremstilling af limonen-4-ol
MX2017016526A (es) 2015-06-17 2018-08-16 Basf Agro Bv Proceso para la preparacion de fenil cetonas sustituidas.
UY36964A (es) 2015-10-27 2017-05-31 Bayer Cropscience Ag Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida
US11168060B2 (en) 2015-12-18 2021-11-09 BASF Agro B.V. Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol
ES2833202T3 (es) 2016-06-15 2021-06-14 Basf Agro Bv Procedimiento para la epoxidación de un alqueno tetrasustituido
KR20190017926A (ko) 2016-06-15 2019-02-20 바스프 아그로 비.브이. 사치환된 알켄의 에폭시화 방법
EP3638650B1 (en) 2017-06-14 2021-06-23 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl alcohols
CN107501210A (zh) * 2017-08-04 2017-12-22 浙江工业大学 一种环氧乙烷衍生物的合成方法
EP3670491A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of 4-nitro-2-trifluoromethyl-acetophenone
EP3670492A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of 4-nitro-2-(trifluoromethyl)-1-(1-nitroethyl)-benzene
EP3670487A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
EP3696159A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
EP3696164A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of 4-nitro-2-(trifluoromethyl)-benzonitrile
EP3696165A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of 4-halophenoxy-2-trifluoromethyl benzonitrile
JP7427096B2 (ja) 2020-08-06 2024-02-02 株式会社クレハ 化合物の製造方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH647513A5 (de) 1979-11-13 1985-01-31 Sandoz Ag Triazol-derivate, deren herstellung und verwendung.
BG48681A3 (en) 1982-12-14 1991-04-15 Ciba Geigy Ag Fungicide means
DE3315681A1 (de) 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
GB2143815B (en) 1983-05-19 1988-01-20 Ciba Geigy Ag Process for the preparation of micro biocidal 1-triazolylethyl ether derivatives
DE3860278D1 (de) 1987-01-21 1990-08-09 Ciba Geigy Ag Mikrobizides mittel.
DE3733755A1 (de) 1987-10-06 1989-04-20 Bayer Ag Verfahren zur herstellung von 2-(4-chlorphenyl-ethyl)-2-tert.-butyl-oxiran
DE4003180A1 (de) 1990-02-03 1991-08-08 Bayer Ag Halogenallyl-azolyl-derivate
DE69616122T2 (de) 1995-03-29 2002-07-04 Sumika Fine Chemicals Co Ltd Verfahren zur Herstellung von (R)-Styroloxiden
AR035858A1 (es) 2001-04-23 2004-07-21 Bayer Corp Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3
US9067941B2 (en) 2010-12-22 2015-06-30 Merck Sharp & Dohme Corp. Fused heterocyclic azaindane carboxamide CGRP receptor antagonists
JP5789340B2 (ja) * 2011-07-13 2015-10-07 ビーエーエスエフ アグロ ベー．ブイ． 殺菌性置換２−［２−ハロゲンアルキル−４−（フェノキシ）−フェニル］−１−［１，２，４］トリアゾール−１−イル−エタノール化合物
CA2840284A1 (en) 2011-07-15 2013-01-24 Basf Se Fungicidal alkyl-substituted 2-[2-chloro-4-(4-chloro-phenoxy)-phenyl]-1-[1,2,4]triazol-1-yl-ethanol compounds
WO2013124791A1 (en) 2012-02-24 2013-08-29 Basf Se Solid form of bosentan
CA2877030A1 (en) 2012-06-22 2013-12-27 Basf Se Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers
WO2014012811A1 (en) 2012-07-18 2014-01-23 Basf Se Process for manufacturing fluoroaromatics
MX360806B (es) 2012-08-17 2018-11-16 Basf Se Benzoxazinonas de carbamato.
US9409894B2 (en) 2012-08-17 2016-08-09 Basf Se Carbamates
US9518045B2 (en) 2012-08-17 2016-12-13 Basf Se Process for manufacturing benzoxazinones
MX2015004947A (es) 2012-10-19 2016-02-22 Basf Se Sistema cristalino multicomponente que comprende nilotinib y formadores de cocristal seleccionados.
ES2742288T3 (es) * 2013-01-09 2020-02-13 Basf Agro Bv Proceso para la preparación de oxiranos y triazoles sustituidos
BR112015016924B1 (pt) 2013-01-16 2020-05-12 Basf Se Método para a preparação do composto de piripiropeno
BR112015020194A2 (pt) 2013-03-07 2017-07-18 Basf Se co-cristais, processo para a preparação dos co-cristais, formulação agrícola, métodos para controle de pragas, para melhoria da saúde das plantas e para a proteção de material de propagação de planta contra pragas e material de propagação de planta
ES2705537T3 (es) 2013-03-28 2019-03-25 Basf Se Producción de piripiropenos a partir de biomasa seca
DK3010895T3 (da) 2013-06-21 2017-11-20 Basf Se Fremgangsmåde til fremstilling af 4-propargyleret aminobenzoxazinoner
EP3024830A2 (en) 2013-07-25 2016-06-01 Basf Se Salts of dasatinib in crystalline form
KR101831535B1 (ko) 2013-07-25 2018-02-22 바스프 에스이 무정형 형태의 다사티닙 염
CN105705495A (zh) 2013-10-17 2016-06-22 巴斯夫欧洲公司 制备取代靛红酸酐化合物及其衍生物的方法
US10045998B2 (en) 2013-12-12 2018-08-14 Basf Se Solid form of abiraterone acetate
EP3083540B1 (en) 2013-12-18 2019-11-20 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
WO2015158518A1 (en) 2014-04-16 2015-10-22 Basf Se Process for manufacturing benzoxazinones
WO2015169883A1 (en) 2014-05-08 2015-11-12 Basf Se Crystalline form b of an anthranilamide insecticide and conversion of form b into form a
US20180230140A1 (en) 2014-06-30 2018-08-16 Basf Se Multicomponent crystals of dasatinib with menthol or vanillin

Also Published As

Publication number Publication date
ES2688377T3 (es) 2018-11-02
IL249663B (en) 2019-05-30
CA2952896A1 (en) 2016-01-14
IL249663A0 (en) 2017-02-28
US10053436B2 (en) 2018-08-21
DK3166932T3 (en) 2018-10-01
US20170166540A1 (en) 2017-06-15
CA2952896C (en) 2022-10-18
WO2016005211A1 (en) 2016-01-14
CN106660979B (zh) 2020-07-07
CN106660979A (zh) 2017-05-10
BR112017000304B1 (pt) 2021-06-29
MX2017000317A (es) 2017-08-25
EP3166932B1 (en) 2018-06-20
EP3166932A1 (en) 2017-05-17

Similar Documents

Publication Publication Date Title
BR112017000304A2 (pt) ?processos para a preparação dos compostos e para a purificação de um produto?
BR112017023932A2 (pt) processo para a preparação de epóxido de terpinoleno
BR112018001400A2 (pt) compostos, processo para a síntese dos compostos, composição, utilização de um composto, método para o combate dos fungos e sementes
BR112017006116A2 (pt) processos de preparação de compostos e compostos
BR112017023950A2 (pt) processo para a preparação de limonen-4-ol
CU24354B1 (es) Procedimiento de obtención de derivados de tetrafluoropropilmorfolina
PH12018501094A1 (en) Process for the preparation of an apoptosis-inducing agent
BR112012022506A2 (pt) preparação de metionina ou selenometionina a partir de homosserina através de um intermediário de lactona.
CL2016000382A1 (es) Procesos para preparar compuestos antivirales
BR112013030830A2 (pt) processo de preparação de composto da fórmula (i) e estetrol obtido diretamente por meio do processo
BR112014024493A2 (pt) método para a produção enzimática de isoprenol usando mevalonato como substrato
BR112018006519A2 (pt) compostos de fórmula, processo para a síntese de compostos, compostos intermediários x, composição, utilização de um composto de fórmula, método para o combate de fungos e semente
BR112018010140A2 (pt) compostos de fórmula, composição, utilização de um composto de fórmula, método para o combate de fungos fitopatogênicos e semente
BR112013016863A2 (pt) processo para produzir um polistereterol
BR112018073490A2 (pt) 6.7.beta-epóxidos esteroides como intermediários químicos
CO6590210A1 (es) Complejo obtenido a partir de mezclas de ácido hialurónico o una sal del mismo y sulfato de condroitina
BR112018010316A2 (pt) compostos de fórmula, composição, utilização de um composto de fórmula, método para o combate de fungos fitopatogênicos e semente
BR112015029399A2 (pt) produção em etapa única de uma composição de polipropileno
NZ720106A (en) A process for the preparation of regadenoson
BR112017011275A2 (pt) composição, e, processo para a produção de xarope de glicose.
BR112015024859A2 (pt) processo e intermediários para a preparação de pregabalina
BR112015015798B8 (pt) Método para a preparação de um composto de fórmula 1
BR112013020966A2 (pt) processo em escala comercial para produção do prrsv
BR112016016397A2 (pt) método para preparar 1-alquil-3-difluorometil-5-fluoro-1h-pirazol-4-carbaldeídos e 1-alquil-3-difluorometil-5-fluoro-1h-pirazol-4-carboxilatos.
CL2015000861A1 (es) Método para producir una solución acuosa de ácido perrénico a partir de sulfuro de renio.

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/06/2015, OBSERVADAS AS CONDICOES LEGAIS.