BR112017000304A2 - ?processos para a preparação dos compostos e para a purificação de um produto? - Google Patents

?processos para a preparação dos compostos e para a purificação de um produto?

Info

Publication number
BR112017000304A2
BR112017000304A2 BR112017000304A BR112017000304A BR112017000304A2 BR 112017000304 A2 BR112017000304 A2 BR 112017000304A2 BR 112017000304 A BR112017000304 A BR 112017000304A BR 112017000304 A BR112017000304 A BR 112017000304A BR 112017000304 A2 BR112017000304 A2 BR 112017000304A2
Authority
BR
Brazil
Prior art keywords
compounds
preparation
purification
processes
product
Prior art date
Application number
BR112017000304A
Other languages
English (en)
Other versions
BR112017000304B1 (pt
Inventor
Gebhardt Joachim
Ehresmann Manfred
Viertelhaus Martin
Goetz Roland
Chiodo Tiziana
Original Assignee
Basf Agro Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Agro Bv filed Critical Basf Agro Bv
Publication of BR112017000304A2 publication Critical patent/BR112017000304A2/pt
Publication of BR112017000304B1 publication Critical patent/BR112017000304B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D301/00—Preparation of oxiranes
    • C07D301/02—Synthesis of the oxirane ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

a presente invenção se refere a um processo para a preparação de compostos de oxirano de fórmula ii a partir de compostos ceto iii utilizando o sulfureto de dimetila (ch3)2s e sulfato de dimetila (ch3)2so4, formando o reagente iv, metilssulfato de trimetilssulfônio [(ch3)3s+ ch3so4-], em solução aquosa na presença de hidróxido de potássio (koh).
BR112017000304-0A 2014-07-08 2015-06-26 Processo para a preparação dos compostos de fórmula ii BR112017000304B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP14176130 2014-07-08
EP14176130.4 2014-07-08
PCT/EP2015/064550 WO2016005211A1 (en) 2014-07-08 2015-06-26 Process for the preparation of substituted oxiranes and triazoles

Publications (2)

Publication Number Publication Date
BR112017000304A2 true BR112017000304A2 (pt) 2017-11-07
BR112017000304B1 BR112017000304B1 (pt) 2021-06-29

Family

ID=51063364

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112017000304-0A BR112017000304B1 (pt) 2014-07-08 2015-06-26 Processo para a preparação dos compostos de fórmula ii

Country Status (10)

Country Link
US (1) US10053436B2 (pt)
EP (1) EP3166932B1 (pt)
CN (1) CN106660979B (pt)
BR (1) BR112017000304B1 (pt)
CA (1) CA2952896C (pt)
DK (1) DK3166932T3 (pt)
ES (1) ES2688377T3 (pt)
IL (1) IL249663B (pt)
MX (1) MX2017000317A (pt)
WO (1) WO2016005211A1 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9981931B2 (en) * 2013-01-09 2018-05-29 BASF Agro B.V. Process for the preparation of substituted oxiranes and triazoles
CN105829274A (zh) 2013-12-18 2016-08-03 巴斯夫农业公司 制备取代的苯氧基苯基酮的方法
EP3294700B1 (en) 2015-05-08 2020-01-29 BASF Agro B.V. A process for the preparation of limonene-4-ol
US10344008B2 (en) 2015-05-08 2019-07-09 BASF Agro B.V. Process for the preparation of terpinolene epoxide
CN107709284B (zh) 2015-06-17 2021-11-23 巴斯夫农业公司 制备取代的苯基酮的方法
UY36964A (es) 2015-10-27 2017-05-31 Bayer Cropscience Ag Combinaciones de principios activos que comprenden un derivado de (tio) carboxamida y un compuesto funguicida
US11168060B2 (en) 2015-12-18 2021-11-09 BASF Agro B.V. Method for producing 2-[4-(4-chlorophenoxy)-2-(trifluoromethyl)phenyl]-1-(1,2,4-triazol-1-yl)propan-2-ol
EP3472138B1 (en) 2016-06-15 2020-08-26 BASF Agro B.V. Process for the epoxidation of a tetrasubstituted alkene
DK3472139T3 (da) 2016-06-15 2021-06-28 Basf Agro Bv Fremgangsmåde til epoxidering af en tetrasubstitueret alken
US10882810B2 (en) 2017-06-14 2021-01-05 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl alcohols
CN107501210A (zh) * 2017-08-04 2017-12-22 浙江工业大学 一种环氧乙烷衍生物的合成方法
EP3670492A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of 4-nitro-2-(trifluoromethyl)-1-(1-nitroethyl)-benzene
EP3670491A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of 4-nitro-2-trifluoromethyl-acetophenone
EP3670487A1 (en) 2018-12-18 2020-06-24 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
EP3696159A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of substituted phenoxyphenyl ketones
EP3696164A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of 4-nitro-2-(trifluoromethyl)-benzonitrile
EP3696165A1 (en) 2019-02-14 2020-08-19 BASF Agro B.V. Process for the preparation of 4-halophenoxy-2-trifluoromethyl benzonitrile
JP7427096B2 (ja) 2020-08-06 2024-02-02 株式会社クレハ 化合物の製造方法

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CH647513A5 (de) 1979-11-13 1985-01-31 Sandoz Ag Triazol-derivate, deren herstellung und verwendung.
BG48681A3 (en) 1982-12-14 1991-04-15 Ciba - Geigy Ag Fungicide means
DE3315681A1 (de) 1983-04-29 1984-10-31 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von oxiranen
ATE66676T1 (de) 1983-05-19 1991-09-15 Ciba Geigy Ag Verfahren zur herstellung von 1triazolylethylether-derivaten, sowie mikrobizide mittel enthaltende neue 1-triazolyl- phenoxyphenylethylether-derivate als wirkstoffe und deren verwendung.
ATE54313T1 (de) 1987-01-21 1990-07-15 Ciba Geigy Ag Mikrobizides mittel.
DE3733755A1 (de) * 1987-10-06 1989-04-20 Bayer Ag Verfahren zur herstellung von 2-(4-chlorphenyl-ethyl)-2-tert.-butyl-oxiran
DE4003180A1 (de) 1990-02-03 1991-08-08 Bayer Ag Halogenallyl-azolyl-derivate
DE69616122T2 (de) 1995-03-29 2002-07-04 Sumika Fine Chemical Co. Ltd., Osaka Verfahren zur Herstellung von (R)-Styroloxiden
AR035858A1 (es) 2001-04-23 2004-07-21 Bayer Corp Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3
US9067941B2 (en) 2010-12-22 2015-06-30 Merck Sharp & Dohme Corp. Fused heterocyclic azaindane carboxamide CGRP receptor antagonists
CN103649057B (zh) * 2011-07-13 2016-05-11 巴斯夫农业公司 杀真菌的取代的2-[2卤代烷基-4-苯氧基苯基]-1-[1,2,4]三唑-1-基乙醇化合物
BR112014000319B1 (pt) 2011-07-15 2019-05-14 Basf Se Usos de compostos da fórmula i, compostos, método de combate a fungos fitopatogênicos, processos de preparação de compostos da fórmula i e composição agroquímica
WO2013124791A1 (en) 2012-02-24 2013-08-29 Basf Se Solid form of bosentan
EP2864313A1 (en) 2012-06-22 2015-04-29 Basf Se Multicomponent crystals comprising imatinib mesilate and selected co-crystal formers
CN104470882B (zh) 2012-07-18 2017-03-29 巴斯夫欧洲公司 生产氟代芳族化合物的方法
AU2013304167B2 (en) 2012-08-17 2017-09-07 Basf Se Process for manufacturing benzoxazinones
MX363058B (es) 2012-08-17 2019-03-06 Basf Se Carbamatos, proceso para su preparación y uso para la preparación de benzoxazinonas.
MX360806B (es) 2012-08-17 2018-11-16 Basf Se Benzoxazinonas de carbamato.
WO2014060449A1 (en) 2012-10-19 2014-04-24 Basf Se Multicomponent crystalline system comprising nilotinib and selected co-crystal formers
US9981931B2 (en) * 2013-01-09 2018-05-29 BASF Agro B.V. Process for the preparation of substituted oxiranes and triazoles
AU2014206958B2 (en) 2013-01-16 2017-08-10 Basf Se Method for preparing a pyripyropene compound
BR112015020194A2 (pt) 2013-03-07 2017-07-18 Basf Se co-cristais, processo para a preparação dos co-cristais, formulação agrícola, métodos para controle de pragas, para melhoria da saúde das plantas e para a proteção de material de propagação de planta contra pragas e material de propagação de planta
DK2978852T3 (en) 2013-03-28 2019-02-18 Basf Se MANUFACTURING PYRIPYROPENES FROM DRY BIOMASS
WO2014202589A1 (en) 2013-06-21 2014-12-24 Basf Se Process for manufacturing 4-propargylated amino-benzoxazinones
KR101831535B1 (ko) 2013-07-25 2018-02-22 바스프 에스이 무정형 형태의 다사티닙 염
WO2015011120A2 (en) 2013-07-25 2015-01-29 Basf Se Salts of dasatinib in crystalline form
US20160229820A1 (en) 2013-10-17 2016-08-11 Basf Se Process for preparing substituted isatoic acid anhydride compounds and derivatives thereof
US10045998B2 (en) 2013-12-12 2018-08-14 Basf Se Solid form of abiraterone acetate
CN105829274A (zh) 2013-12-18 2016-08-03 巴斯夫农业公司 制备取代的苯氧基苯基酮的方法
WO2015158518A1 (en) 2014-04-16 2015-10-22 Basf Se Process for manufacturing benzoxazinones
WO2015169883A1 (en) 2014-05-08 2015-11-12 Basf Se Crystalline form b of an anthranilamide insecticide and conversion of form b into form a
EP3160963A1 (en) 2014-06-30 2017-05-03 Basf Se Multicomponent crystals of dasatinib with menthol or vanillin

Also Published As

Publication number Publication date
EP3166932B1 (en) 2018-06-20
IL249663A0 (en) 2017-02-28
MX2017000317A (es) 2017-08-25
CN106660979A (zh) 2017-05-10
CA2952896A1 (en) 2016-01-14
CA2952896C (en) 2022-10-18
US20170166540A1 (en) 2017-06-15
EP3166932A1 (en) 2017-05-17
ES2688377T3 (es) 2018-11-02
BR112017000304B1 (pt) 2021-06-29
CN106660979B (zh) 2020-07-07
IL249663B (en) 2019-05-30
DK3166932T3 (en) 2018-10-01
US10053436B2 (en) 2018-08-21
WO2016005211A1 (en) 2016-01-14

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Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/06/2015, OBSERVADAS AS CONDICOES LEGAIS.