CO5221038A1 - Naftopiranos polialcoxilados polimerizables - Google Patents

Naftopiranos polialcoxilados polimerizables

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Publication number
CO5221038A1
CO5221038A1 CO99057899A CO99057899A CO5221038A1 CO 5221038 A1 CO5221038 A1 CO 5221038A1 CO 99057899 A CO99057899 A CO 99057899A CO 99057899 A CO99057899 A CO 99057899A CO 5221038 A1 CO5221038 A1 CO 5221038A1
Authority
CO
Colombia
Prior art keywords
alkyl
alkoxy
phenyl
group
monosubstituted
Prior art date
Application number
CO99057899A
Other languages
English (en)
Inventor
Gemert Barry Van
Chopra Anu
Kumar Anil
Original Assignee
Ppg Ind Ohio Inc
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Filing date
Publication date
Application filed by Ppg Ind Ohio Inc filed Critical Ppg Ind Ohio Inc
Publication of CO5221038A1 publication Critical patent/CO5221038A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/3311—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group
    • C08G65/3314—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group cyclic
    • C08G65/3315—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group cyclic aromatic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/3311—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group
    • C08G65/3318—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing a hydroxy group heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/334—Polymers modified by chemical after-treatment with organic compounds containing sulfur
    • C08G65/3344—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur
    • C08G65/3346—Polymers modified by chemical after-treatment with organic compounds containing sulfur containing oxygen in addition to sulfur having sulfur bound to carbon and oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/15—Heterocyclic compounds having oxygen in the ring
    • C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
    • C08K5/1545—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B57/00—Other synthetic dyes of known constitution
    • C09B57/02—Coumarine dyes
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K9/00—Tenebrescent materials, i.e. materials for which the range of wavelengths for energy absorption is changed as a result of excitation by some form of energy
    • C09K9/02—Organic tenebrescent materials
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • General Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Pyrane Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Eyeglasses (AREA)

Abstract

Un compuesto naftopirano representado por las siguientes fórmulas gráficas:<EMI FILE="99057899_1" ID="1" IMF=JPEG >Donde, (a) R1, R3, R4, R5 o R6 es el grupo R representado por la fórmula: -A[C2H40)x (C3H60)y (C4H80)2]D donde -A es -C(O)O, -CH2O ó -O, y D es un grupo polimerizable, cada uno de x, y y z, son un número entre 0 y 50, y la suma de x, y y z está entre 1 y 50; R2 es el grupo R o fenilo monosubstituido con R; con tal que exista al menos un grupo R o fenilo monosubstituido con R en la porción nafto indeno de dicho naftopirano; o (b) R1 es hidrógeno, alquilo de C1-C3 o el grupo, -C(O)W, donde W es -OR2, -N(R8)R9, piperidino o morfolino, donde R7 es alilo, alquilo de C1-C6, fenilo, fenilo monosubstituido con alquilo de (C1-C6), fenilo monosubstituido con alcoxi de (C1-C6), fenilalquilo de (C1-C3), fenilalquilo de (C1-C3) monosubstituido con alquilo de (C1-C6), fenilalquilo de (C1-C3) monosubstituido con alcoxi de (C1-C6), (C1-C6) alcoxi (C2-C4) alquilo, o haloalquilo deC1-C6; R8 y R9 son seleccionados cada uno del grupo que consta de alquilo de C1-C6, cicloalquilo de C5-C7, fenilo, fenilo monosubstituido y fenilo di- substituido, siendo dichos substituyentes de fenilo alquilo de C1-C6 y alcoxi de C1-C6, y donde dicho substituyente halo es cloro o fluor; (c) R2, cada R3 y R4 se seleccionan del grupo que consta de hidrógeno, alquilo de C1-C6, cicloalquilo de C3-C7, fenilo,- 2 -fenilo monosubstituido o fenilo disubstituido y los grupos -OR10 y -OC(O)R10, donde R10 es alquilo C1-C6, fenilalquilo de C1-C3), fenilalquilo de (C1- C3) monosubstituido con alquilo de (C1-C6), fenilalquilo de (C1-C3) monosubstituido con alcoxi de (C1- C6), (C1-C6)alcoxi(C2-C4)alquilo, cicloalquilo de C3-C7 o cialoalquilo de C3-C7 monosubstituido con alquilo de (C1-C4), y n se selecciona de los enteros 0, 1 y 2 y dichos substituyentes de fenilo son alquilo de (C1-C6) o alcoxi de (C1-C6); (d) R5 y R6 forman juntos un grupo oxo, un grupo espiro heterociclico, que contiene 2 átomos de oxígeno y de 3 a 6 átomos de carbono incluyendo el átomo espirocarbono; o R5 y R6 son cada uno de ellos hidrógeno, hidroxi, alquilo de C1-C6, cicloalquilo de C3-C7, alilo, fenilo, fenilo, monosubstituido, bencilo, bencilo monosubstituido, cloro, flúor, el grupo -C(O)X, donde X es hidroxi, alquilo de C1-C6, fenilo, fenilo monosubstituido, amino, monoalquilamino de (C1-C6), o dialquilamino de (C1-C6); o R5 y R6 son cada uno de ellos el grupo -OR11, donde R11 es alquilo de C1- C6, fenilalquilo de (C1-C3), fenilalquilo de (C1-C3) monosubstituido con alquilo de (C1-C6), fenilalcoxi de (C1-C3) monosubstituido con alcoxi de (C1-C6), (C1-C6), alcoxi(C2-C4)alquilo, cicloalquilo de C3-C7, cicloalquilo de C3-C7 monosubstituido con alquilo de (C1-C4), cloroalquilo de C1-C6, fluoralquilo de C1- C6, alilo, el grupo -CH(R13)Y, donde R12 es hidrógeno o alquilo de C1-C3, e Y es CN, CF3, o COOR13, R13 es hidrógeno o alquilo de C1-C3; o R11 es el grupo, -C(O)Z, donde Z es hidrógeno, alquilo de C1- C6, alcoxi de C1-C6, los grupos arilo no substituidos, mono- o di- substituidos, fenilo o naftilo, fenoxi, fenoxi mono o di-susbstituido con alquilo de (C1-C6), fenoxi mono o di-substituido con alcoxi de (C1-C6), fenoxi mono o di-substituido con alcoxi de (C1-C6), amino,monoalquilamino de (C1-C6), dialquilamino de (C1-C6), fenilamino, fenilamino mono o di-substituido con alquilo de (C1-C6), o fenilamino mono o di- substituido alcoxi de (C1-C6), siendo cada uno de dichos substituyentes de los grupos fenilo, bencilo y arilo, alquilo de C1-C6 o alcoxi de C1-C6; y (e) B es fenilo monosubstituido con R; (f) BAND#39 se selecciona del grupo que consta de: (i) los grupos arilo no substituidos, mono-, di y tri-substituidos, fenilo y naftilo; (ii) los grupos heteroaromáticos no substituidos, mono- y di-substituidos piridilo, furanilo, benzofuran-2-ilo, benzofuran-3-ilo, tienilo, benzotien-2-ilo, benzotien-3-ilo, dibenzofuranilo, dibenzotienilo, carbazolilo y fluorenilo, siendo seleccionado cada uno de dichos substituyentes arilo y heteroaromáticos en (f) (i) y (ii) a partir del grupo que consta de hidroxi, arilo, monoalcoxiarilo de (C1-C6), dialcoxiarilo de (C1-C6), monoalquilarilo de (C1-C6), dialquilarilo de (C1-C6), cIoroarilo, fluorarilo, cicloalquilarilo de C3-C7, cicloalquilo de C3-C7, cicloalquiloxi de C3-C7, (C3-C7) cicloalquiloxi C1-C6 alquilo, (C3-C7) cicloalquiloxi C1-C6 alcoxi, arilalquilo de (C1-C6), arilalcoxi de (C1-C6), ariloxi, ariloxialquilo de (C1-C6), ariloxialcoxi de (C1-C6), mono- y di-alquilarilo de (C1-C6) alquilo de (C1-C6) mono- y di-alcoxiarilo de (C1-C6) alquilo de (C1-C6), mono- y di-alquilarilo de (C1-C6) alcoxi de (C1-C6), mono- y di-alcoxiarilo de (C1-C6) alcoxi de (C1-C6), amino, monoalquilamino de (C1-C6), dialquil-amino de (C1-C6), diarilamino, N- alquilpiperacino de (C1-C6), N-arilpipe-racino, aciridino, indolino, piperidino, arilpiperidino, morfolino, tiomorfolino, tetra-hidroquinolino, tetrahidroisoquinolino, pirrilo, alquilo de C1-C6, cIoroalquilo de C1-C6, fluoralquilo de C1-C6, alcoxi de C1-C6, mono(C1-C6)alcoxi(C1-C4) alquilo, acriloxi, metacriloxi, bromo, cloro y flúor; (iii) los grupos representados por las siguientes fórmulas gráficas:<EMI FILE="99057899_2" ID="2" IMF=JPEG >Donde E es carbono u oxígeno y C es oxígeno o nitrógeno substituido, con tal que cuando G sea nitrógeno substituido, E sea carbono, siendo seleccionados dichos substituyentes de nitrógeno del grupo que consta de hidrógeno, alquilo de C1-C6, y acilo de C2-C6; cada R14 es alquilo de C1-C6, alcoxi de C1-C6, hidroxi, cloro o flúor; R16 y R16 son cada uno de ellos es hidrógeno o alquilo de C1-C6; y q es el entero 0, 1 ó 2; (iv) alquilo de C1-C6, cIoroalquilo de C1-C6; fluoralquilo de C1-C6, y C1-C6 alcoxi (C1- C4)alquilo; y (v) el grupo representado por la siguiente fórmula gráfica VC:<EMI FILE="99057899_3" ID="3" IMF=JPEG >Donde L es hidrógeno o alquilo de C1-C4, y M es seleccionado de los miembros no substituidos, mono- y di-substituidos del grupo que consta de naftilo, fenilo, furanilo y tienilo, siendo cada uno de dichos grupos substituyentes alquilo de C1-C4, alcoxi de C1-C4, flúor o cloro.
CO99057899A 1998-09-11 1999-09-13 Naftopiranos polialcoxilados polimerizables CO5221038A1 (es)

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US15191198A 1998-09-11 1998-09-11

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Country Status (10)

Country Link
US (1) US6113814A (es)
EP (1) EP1112263B1 (es)
JP (1) JP4531984B2 (es)
AU (1) AU761180B2 (es)
BR (1) BR9913869A (es)
CA (1) CA2343310C (es)
CO (1) CO5221038A1 (es)
DE (1) DE69925742T2 (es)
ES (1) ES2244213T3 (es)
WO (1) WO2000015629A1 (es)

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