CO5180554A1 - Nuevos derivados del benceno que comprenden una funcion amina sustituida con un grupo alquilo y un grupo cicloalquilo, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen. - Google Patents

Nuevos derivados del benceno que comprenden una funcion amina sustituida con un grupo alquilo y un grupo cicloalquilo, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen.

Info

Publication number
CO5180554A1
CO5180554A1 CO00042775A CO00042775A CO5180554A1 CO 5180554 A1 CO5180554 A1 CO 5180554A1 CO 00042775 A CO00042775 A CO 00042775A CO 00042775 A CO00042775 A CO 00042775A CO 5180554 A1 CO5180554 A1 CO 5180554A1
Authority
CO
Colombia
Prior art keywords
group
cyclalkyll
amina
benzene
understand
Prior art date
Application number
CO00042775A
Other languages
English (en)
Inventor
Robert Boigegrain
Bourrie Bernard
Casellas Pierre
Herbert Jean Marc
Lair Pierre
Nisato Dino
Paul Raymond
Jean Claude Vernieres
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of CO5180554A1 publication Critical patent/CO5180554A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
    • C07C211/35—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing only non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/40—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing only non-condensed rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Compuestos de fórmula<EMI FILE="00042775_1" ID="1" IMF=JPEG >en la cual:-A representa un grupo seleccionado entre los siguientes:-C=C-, CH=CH-; -CH2-CH2-- n es igual a 1 ó 2 ;- X representa un átomo de hidrógeno, de cloro o de flúor o un grupo metilo o metoxi;- Y representa un átomo de hidrógeno o un átomo de cloro o de flúor;- R1 representa un grupo ciclohexilo monosustituido, disustituido, trisustituido ó tetrasustituido por un grupo metilo; un grupo fenilo monosustituido o disustituido por un átomo de flúor o de cloro o por un grupo metoxi; un grupo cicloheptilo, tert-butilo, diciclopropilmetilo, biciclo[3.2.1]octanilo, 4-tetrahidropiranilo, 4-tetrahidrotiopiranilo o adamantilo 1 ó 2 adamantan-2-ol; ó R1 representa un grupo fenilo, entendiéndose que en este caso X e Y son diferentes del hidrógeno;- R2 representa un átomo de hidrógeno o un grupo (C1-C4)alquilo eventualmente sustituido por un grupo trifluorometilo;-R3 representa un (C5-C7) cicloalquilo;y las sales de adición de estos compuestos con ácidos farmacéuticamente aceptables, así como sus solvatos e hidratos.
CO00042775A 1999-06-11 2000-06-08 Nuevos derivados del benceno que comprenden una funcion amina sustituida con un grupo alquilo y un grupo cicloalquilo, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen. CO5180554A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9907396A FR2794742B1 (fr) 1999-06-11 1999-06-11 Nouveaux derives du benzene, un procede pour leur preparation et les compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
CO5180554A1 true CO5180554A1 (es) 2002-07-30

Family

ID=9546664

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00042775A CO5180554A1 (es) 1999-06-11 2000-06-08 Nuevos derivados del benceno que comprenden una funcion amina sustituida con un grupo alquilo y un grupo cicloalquilo, un procedimiento para su preparacion y las composiciones farmaceuticas que los contienen.

Country Status (33)

Country Link
US (1) US6482986B1 (es)
EP (1) EP1192122B1 (es)
JP (1) JP4711579B2 (es)
KR (1) KR100668581B1 (es)
CN (1) CN1210250C (es)
AR (1) AR033793A1 (es)
AT (1) ATE252542T1 (es)
AU (1) AU768420B2 (es)
BR (1) BR0011738A (es)
CA (1) CA2374631C (es)
CO (1) CO5180554A1 (es)
CZ (1) CZ299659B6 (es)
DE (1) DE60006113T2 (es)
DK (1) DK1192122T3 (es)
ES (1) ES2208345T3 (es)
FR (1) FR2794742B1 (es)
HK (1) HK1042891B (es)
HU (1) HU228683B1 (es)
IL (1) IL146545A0 (es)
MX (1) MXPA01012783A (es)
NO (1) NO327778B1 (es)
NZ (1) NZ515529A (es)
PL (1) PL196491B1 (es)
PT (1) PT1192122E (es)
RS (1) RS49998B (es)
RU (1) RU2248964C2 (es)
SI (1) SI1192122T1 (es)
SK (1) SK286390B6 (es)
TW (1) TWI279398B (es)
UA (1) UA71959C2 (es)
UY (1) UY26199A1 (es)
WO (1) WO2000076953A1 (es)
ZA (1) ZA200109486B (es)

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GB2410947B (en) * 2004-02-11 2008-09-17 Cambridge Lab Ltd Pharmaceutical compounds
WO2006115509A2 (en) 2004-06-24 2006-11-02 Novartis Vaccines And Diagnostics Inc. Small molecule immunopotentiators and assays for their detection
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
CN101184732B (zh) 2005-03-28 2012-05-16 株式会社半导体能源研究所 蒽衍生物、发光元件用材料、发光元件、发光装置和电子器件
FR2887454B1 (fr) * 2005-06-28 2009-06-05 Sanofi Aventis Sa Combinaisons antitumorales contenant des derives du taxane et des sigma ligands
GB0514501D0 (en) * 2005-07-14 2005-08-24 Cambridge Lab Ireland Ltd Pharmaceutical compounds
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US7731377B2 (en) * 2006-03-21 2010-06-08 Semiconductor Energy Laboratory Co., Ltd. Backlight device and display device
CN101506163B (zh) * 2006-08-30 2012-05-02 株式会社半导体能源研究所 合成蒽衍生物的方法和蒽衍生物、发光元件、发光装置、电子装置
GR1005865B (el) * 2007-01-17 2008-04-07 Anavex Life Sciences Corp. Νεοι συνδετες των σιγμα υποδοχεων με αντι-αποπτωτικες και/η προ-αποπτωτικες ιδιοτητες επι των κυτταρικων βιοχημικων μηχανισμων, με νευρο-προστατευτικη, αντικαρκινικη, αντι-μεταστατικη και αντι- αντι-(χρονιο)φλεγμονικη δραση.
US7723722B2 (en) 2007-03-23 2010-05-25 Semiconductor Energy Laboratory Co., Ltd. Organic compound, anthracene derivative, and light-emitting element, light-emitting device, and electronic device using anthracene derivative
FR2915994B1 (fr) * 2007-05-11 2009-07-03 Galderma Res & Dev Procede de synthese de l'acide (z)-3-[2-butoxy-3'-(3-heptyl-1-methyl-ureido)-biphenyl-4-yl] -2-methoxy-acrylique.
US20080286445A1 (en) * 2007-05-17 2008-11-20 Semiconductor Energy Laboratory Co., Ltd. Composition, and method of fabricating light-emitting element
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GB2462611A (en) * 2008-08-12 2010-02-17 Cambridge Lab Pharmaceutical composition comprising tetrabenazine
GB2463452A (en) * 2008-09-08 2010-03-17 Cambridge Lab Desmethyl derivatives of tetrabenazine and pharmaceutical compositions thereof
GB2463451A (en) * 2008-09-08 2010-03-17 Cambridge Lab 3, 11b cis-dihydrotetrabenazine compounds for use in the treatment of dementia
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EP2166001B1 (en) * 2008-09-19 2011-07-20 Semiconductor Energy Laboratory Co., Ltd. Carbazole Derivative and Method for Producing the Same
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GR1006794B (el) 2009-02-26 2010-06-04 Αλεξανδρος Βαμβακιδης Προσδετες των σιγμα υποδοχεων, αντι-αποπτωτικες και προ-αποπτωτικες ιδιοτητες επι των κυτταρικων μηχανισμων, και με πρωτοτυπη κυτταρο-προστατευτικη αλλα και αντικαρκινικη δραση
KR102225715B1 (ko) * 2013-07-09 2021-03-09 토소가부시키가이샤 아다만틸기를 가진 환상 아진 화합물, 제조 방법, 및 상기 화합물을 구성 성분으로서 함유하는 유기 전계발광소자
KR20170101128A (ko) 2016-02-26 2017-09-05 가부시키가이샤 한도오따이 에네루기 켄큐쇼 유기 화합물, 발광 소자, 발광 장치, 전자 기기, 및 조명 장치
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Also Published As

Publication number Publication date
ATE252542T1 (de) 2003-11-15
FR2794742A1 (fr) 2000-12-15
RS49998B (sr) 2008-09-29
KR20020009632A (ko) 2002-02-01
MXPA01012783A (es) 2002-09-18
SI1192122T1 (en) 2004-04-30
CZ20014443A3 (cs) 2002-05-15
NO327778B1 (no) 2009-09-21
CN1210250C (zh) 2005-07-13
US6482986B1 (en) 2002-11-19
CZ299659B6 (cs) 2008-10-08
PL352742A1 (en) 2003-09-08
HK1042891B (zh) 2004-04-08
CN1355782A (zh) 2002-06-26
DK1192122T3 (da) 2004-03-01
IL146545A0 (en) 2002-07-25
HK1042891A1 (en) 2002-08-30
DE60006113D1 (de) 2003-11-27
ES2208345T3 (es) 2004-06-16
AR033793A1 (es) 2004-01-07
CA2374631C (en) 2010-10-19
EP1192122B1 (fr) 2003-10-22
CA2374631A1 (en) 2000-12-21
NO20016038L (no) 2002-02-11
NZ515529A (en) 2004-01-30
NO20016038D0 (no) 2001-12-10
JP2003502306A (ja) 2003-01-21
YU87101A (sh) 2004-07-15
AU5539600A (en) 2001-01-02
SK18062001A3 (sk) 2002-05-09
HU228683B1 (en) 2013-05-28
PT1192122E (pt) 2004-03-31
SK286390B6 (sk) 2008-09-05
JP4711579B2 (ja) 2011-06-29
EP1192122A1 (fr) 2002-04-03
HUP0201953A2 (hu) 2002-12-28
UY26199A1 (es) 2001-01-31
UA71959C2 (en) 2005-01-17
RU2248964C2 (ru) 2005-03-27
FR2794742B1 (fr) 2005-06-03
BR0011738A (pt) 2002-03-05
TWI279398B (en) 2007-04-21
AU768420B2 (en) 2003-12-11
PL196491B1 (pl) 2008-01-31
HUP0201953A3 (en) 2006-03-28
DE60006113T2 (de) 2004-07-15
WO2000076953A1 (fr) 2000-12-21
KR100668581B1 (ko) 2007-01-17
ZA200109486B (en) 2002-11-18

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