CO4910140A1 - Intermediarios y proceso para preparar olanzapina - Google Patents

Intermediarios y proceso para preparar olanzapina

Info

Publication number
CO4910140A1
CO4910140A1 CO97055061A CO97055061A CO4910140A1 CO 4910140 A1 CO4910140 A1 CO 4910140A1 CO 97055061 A CO97055061 A CO 97055061A CO 97055061 A CO97055061 A CO 97055061A CO 4910140 A1 CO4910140 A1 CO 4910140A1
Authority
CO
Colombia
Prior art keywords
intermediaries
olanzapine
prepare olanzapine
prepare
drying
Prior art date
Application number
CO97055061A
Other languages
English (en)
Spanish (es)
Inventor
Charles Arthur Bunnell
Samuel Dean Larsen
John Richard Nichols
Susan Marie Reutzel
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO4910140(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CO4910140A1 publication Critical patent/CO4910140A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CO97055061A 1996-09-23 1997-09-22 Intermediarios y proceso para preparar olanzapina CO4910140A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23

Publications (1)

Publication Number Publication Date
CO4910140A1 true CO4910140A1 (es) 2000-04-24

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97055061A CO4910140A1 (es) 1996-09-23 1997-09-22 Intermediarios y proceso para preparar olanzapina

Country Status (35)

Country Link
US (1) US6020487A (enExample)
EP (1) EP0831098B1 (enExample)
JP (2) JP2001500877A (enExample)
KR (1) KR100560015B1 (enExample)
CN (1) CN1122036C (enExample)
AR (1) AR013838A1 (enExample)
AT (1) ATE209208T1 (enExample)
AU (1) AU719441B2 (enExample)
BR (1) BR9712100A (enExample)
CA (1) CA2265712C (enExample)
CO (1) CO4910140A1 (enExample)
CZ (1) CZ299248B6 (enExample)
DE (1) DE69708428T2 (enExample)
DK (1) DK0831098T3 (enExample)
EA (1) EA001642B1 (enExample)
EG (1) EG23861A (enExample)
ES (1) ES2166051T3 (enExample)
HU (1) HU226484B1 (enExample)
ID (1) ID27275A (enExample)
IL (1) IL128962A (enExample)
IN (1) IN187156B (enExample)
MY (1) MY125565A (enExample)
NO (1) NO323980B1 (enExample)
NZ (1) NZ334448A (enExample)
PE (1) PE110398A1 (enExample)
PL (3) PL196068B1 (enExample)
PT (1) PT831098E (enExample)
RS (1) RS49598B (enExample)
SI (1) SI0831098T1 (enExample)
SV (1) SV1997000081A (enExample)
TR (1) TR199900640T2 (enExample)
TW (1) TW470746B (enExample)
UA (1) UA59371C2 (enExample)
WO (1) WO1998012199A1 (enExample)
ZA (1) ZA978515B (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2420987A1 (en) * 2000-08-31 2002-03-07 Dr. Reddy's Laboratories Ltd. Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
CA2464306A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
CH695862A5 (fr) 2001-12-24 2006-09-29 Sun Pharmaceutical Ind Ltd Forme cristalline I de la methyl-4-(4-methyl-1-piperazinyl) 10H-thieno [2,3-b] [1,5] benzodiazepine.
AU2003243153A1 (en) * 2002-04-23 2003-11-10 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
US7297789B2 (en) 2002-05-31 2007-11-20 Sandoz, Inc. Process of preparation of olanzapine form I
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
JP2007511605A (ja) * 2003-11-18 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オランザピン含有経皮薬物送達組成物
WO2005063771A1 (en) * 2003-12-22 2005-07-14 Teva Pharmaceutical Industries Ltd Methods of preparing olanzapine
ATE504588T1 (de) 2004-01-27 2011-04-15 Synthon Bv Stabile salze von olanzapin
EP1716154A1 (en) * 2004-02-19 2006-11-02 Neuland Laboratories Ltd Process for the preparation of olanzapine form 1 useful as antipsychotic drug
EP1781666A1 (en) * 2004-07-14 2007-05-09 Shasun Chemicals and Drugs Limited Improved process for making form i of olanzapine.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
ES2303462B1 (es) 2004-09-06 2009-06-05 Shasun Chemicals And Drugs Limited Nuevo procedimiento para la preparacion de una forma polimorfica i de olanzapina farmaceuticamente pura.
EP2623095A1 (en) * 2004-11-16 2013-08-07 Elan Pharma International Limited Injectable nanoparticulate olanzapine formulations
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
DE69329887T2 (de) * 1992-05-29 2001-05-23 Eli Lilly And Co., Ltd. Thienobenzodiazepinderivate zur Behandlung von Störungen des Zentralnervensystems
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
AU720366B2 (en) * 1996-09-23 2000-06-01 Eli Lilly And Company Olanzapine dihydrate D

Also Published As

Publication number Publication date
PL194565B1 (pl) 2007-06-29
EP0831098A2 (en) 1998-03-25
PL332482A1 (en) 1999-09-13
IL128962A0 (en) 2000-02-17
PT831098E (pt) 2002-04-29
HUP0000066A2 (hu) 2000-06-28
CZ299248B6 (cs) 2008-05-28
SV1997000081A (es) 1999-01-14
ZA978515B (en) 1999-03-23
DK0831098T3 (da) 2002-05-21
TR199900640T2 (xx) 1999-06-21
CN1234802A (zh) 1999-11-10
EP0831098B1 (en) 2001-11-21
PE110398A1 (es) 1999-01-14
DE69708428D1 (de) 2002-01-03
AR013838A1 (es) 2001-01-31
HUP0000066A3 (en) 2000-11-28
BR9712100A (pt) 1999-08-31
CN1122036C (zh) 2003-09-24
EG23861A (en) 2007-11-18
IN187156B (enExample) 2002-02-16
EA199900326A1 (ru) 1999-08-26
CA2265712C (en) 2006-10-31
ES2166051T3 (es) 2002-04-01
DE69708428T2 (de) 2002-07-04
JP2009242407A (ja) 2009-10-22
HK1009807A1 (en) 1999-06-11
AU719441B2 (en) 2000-05-11
PL196068B1 (pl) 2007-12-31
RS49598B (sr) 2007-06-04
TW470746B (en) 2002-01-01
SI0831098T1 (en) 2002-04-30
AU4484197A (en) 1998-04-14
MY125565A (en) 2006-08-30
KR20000048520A (ko) 2000-07-25
NZ334448A (en) 2000-08-25
WO1998012199A1 (en) 1998-03-26
KR100560015B1 (ko) 2006-03-15
EP0831098A3 (en) 1998-04-29
NO991382L (no) 1999-03-22
EA001642B1 (ru) 2001-06-25
CZ99099A3 (cs) 1999-11-17
NO991382D0 (no) 1999-03-22
IL128962A (en) 2003-01-12
US6020487A (en) 2000-02-01
ATE209208T1 (de) 2001-12-15
NO323980B1 (no) 2007-07-30
CA2265712A1 (en) 1998-03-26
JP2001500877A (ja) 2001-01-23
HU226484B1 (en) 2009-03-02
PL196069B1 (pl) 2007-12-31
UA59371C2 (uk) 2003-09-15
ID27275A (id) 2001-03-22
YU15599A (sh) 2001-12-26

Similar Documents

Publication Publication Date Title
ID27036A (id) Pirazolopirimidinona penghambat cgmp pde5 untuk pengobatan kelainan fungsi seksual
AR002651A1 (es) Procedimiento integrado para la producción de 1-buteno
NO20011936L (no) Fremgangsmate for fremstilling av citalopram
ATE294054T1 (de) Methode zur herstellung einer gemusterten betonoberfläche
ES525304A0 (es) Procedimiento para la produccion de velulosa
ES543147A0 (es) Procedimiento para la obtencion de 1,2-diacil-sn-glicero-3- fosfocolinas y 1,2-diacil-sn-glicero-3-fosfoetanolaminas sustituidas en forma mixta
EA200100208A1 (ru) Новая форма соли пантопразола
BR8704372A (pt) Came para freios com sapata interna de expansao
HUP0000066A2 (hu) Olanzapin-dihidrát és eljárás olanzapin II forma előállítására
ID22572A (id) Proses yang disempurnakan untuk pembuatan 3,5,5-trimetilsikloheksa-3-en-1-on (betha-isoforon) dengan isomerisasi 3,5,5-trimetilsikloheksa-2-en-1-on (alpha-isoforon) (ii)
DE50009949D1 (de) Verfahren zur Herstellung von natriumionenarmen Diazoniumverbindungen
DE69902120D1 (de) Verfahren zur Herstellung von Acetylenderivaten
MX9102521A (es) Metodo para formar paquetes de tira metalica amorfa para fabricacion de nucleos de transformador.
EE9900373A (et) Protsess bensotiasoloonühendite valmistamiseks
DE60005586D1 (de) Verfahren zur Herstellung alkylsubstituierter Hydrochinone
ES2020158A4 (es) Procedimiento para la produccion de monosulfuro sodico
NO20012811D0 (no) Fremgangsmåte for fremstilling av p-klorfenyl-propanol- derivat
ES2184151T3 (es) Procedimiento para preparar derivados de cianofosfonato a partir de anhidrido fosforico y cianuro.
NO20013044L (no) Fremgangsmåte for fremstilling av NG-substituerte deaza- adenosinderivater
ES524427A0 (es) Procedimiento para la obtencion de dihidrato de dicloroisocianurato sodico
DE69925716D1 (de) Verfahren zur herstellung heteroaromatischer aldehyde
DE59907804D1 (de) Verbessertes verfahren zur herstellung von pharmazeutisch wertvollen norbenzomorphanderivaten
DK173787D0 (da) Lavluminansgitter for belysningsarmaturer
ES1010419Y (es) Pieza para la formacion de zocalos.
ES2112819T1 (es) Procedimiento para la preparacion de penicilinas.