CO4810231A1 - Nuevas sulfonamidas naftil- y anilido - substituidas - Google Patents

Nuevas sulfonamidas naftil- y anilido - substituidas

Info

Publication number
CO4810231A1
CO4810231A1 CO99003181A CO99003181A CO4810231A1 CO 4810231 A1 CO4810231 A1 CO 4810231A1 CO 99003181 A CO99003181 A CO 99003181A CO 99003181 A CO99003181 A CO 99003181A CO 4810231 A1 CO4810231 A1 CO 4810231A1
Authority
CO
Colombia
Prior art keywords
chain
alkyl
halogen
carbon atoms
branched
Prior art date
Application number
CO99003181A
Other languages
English (en)
Inventor
Wolfgang Bender
Jurgen Reefschlager
Peter Eckenberg
Siegfried Goldmann
Michael Harter
Sabine Hallenberger
Jorg Trappe
Olaf Webwer
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CO4810231A1 publication Critical patent/CO4810231A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C07C311/38Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
    • C07C311/44Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/45Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
    • C07C311/46Y being a hydrogen or a carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/041,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/061,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/56Ring systems containing bridged rings
    • C07C2603/58Ring systems containing bridged rings containing three rings
    • C07C2603/70Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74Adamantanes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Epoxy Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Sulfonamidas de fórmula general (I)en la queR1 y R2 son iguales o distintos y representan hidrógeno, formilo, fenilo o bencilo dado el caso substituidos con uno a tres átomos de halógeno, o alquilo o acilo de cadena lineal o ramificados de hasta 6 átomos de carbono respectivamente, pudiendo estar alquilo o acilo dado el caso substituidos con uno a tres subtituyentes escogidos entre halógeno e hidroxi,A, D, E, y G son iguales o distintos y representan hidrógeno, halógeno, nitro, ciano, hidroxi, carboxilo, trifluorometilo, trifluorometoxi o alquilo, alcoxi o alcoxicarbonilo de cadena lineal o ramificados de hasta 5 átomos de carbono respectivamente,R3 representa alquenilo de cadena lineal o ramificado de hasta 6 átomos de carbono, orepresenta alquilo de cadena lineal o ramificado de hasta 8 átomos de carbono, que dado el caso porta un grupo amino que puede estar substituido con alquilo de hasta 4 átomos de carbono o con un grupo protector de amino, o el alquilo está substituido, dado el caso, de una a tres veces de forma igual o distinta con hidroxi, ciano, halógeno, azido, nitro, trifluorometilo, carboxilo o fenilo, que a su vez puede estar hasta disubstituido de forma igual o diferente con nitro, halógeno, hidroxi o con alquilo o alcoxi de cadena lineal o ramificada de hasta 4 átomos de carbono, oR3 representa restos de fórmulas
CO99003181A 1998-01-23 1999-01-21 Nuevas sulfonamidas naftil- y anilido - substituidas CO4810231A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19802439 1998-01-23

Publications (1)

Publication Number Publication Date
CO4810231A1 true CO4810231A1 (es) 1999-06-30

Family

ID=7855411

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99003181A CO4810231A1 (es) 1998-01-23 1999-01-21 Nuevas sulfonamidas naftil- y anilido - substituidas

Country Status (30)

Country Link
US (1) US6417181B1 (es)
EP (1) EP1049666B1 (es)
JP (1) JP2002501043A (es)
KR (1) KR20010034321A (es)
CN (1) CN1294578A (es)
AR (1) AR016978A1 (es)
AT (1) ATE242207T1 (es)
AU (1) AU2420799A (es)
BG (1) BG104617A (es)
BR (1) BR9907738A (es)
CA (1) CA2318182A1 (es)
CO (1) CO4810231A1 (es)
DE (1) DE59905829D1 (es)
EE (1) EE200000432A (es)
ES (1) ES2201666T3 (es)
GT (1) GT199900010A (es)
HR (1) HRP20000532A2 (es)
HU (1) HUP0200918A2 (es)
ID (1) ID25448A (es)
IL (1) IL137159A0 (es)
NO (1) NO20003601L (es)
NZ (1) NZ505900A (es)
PE (1) PE20000181A1 (es)
PL (1) PL341815A1 (es)
SK (1) SK11012000A3 (es)
SV (1) SV1999000006A (es)
TR (1) TR200002140T2 (es)
TW (1) TW461880B (es)
WO (1) WO1999037609A1 (es)
ZA (1) ZA99473B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19919793A1 (de) * 1999-04-30 2000-11-02 Bayer Ag Neue Sulfonamide
DE19920790A1 (de) * 1999-05-06 2000-11-09 Bayer Ag Bis-Sulfonamide mit anti-HCMV-Wirkung
DE19934321A1 (de) * 1999-07-21 2001-01-25 Bayer Ag Naphthyl-substituierte Sulfonamide
DE19934295A1 (de) * 1999-07-21 2001-01-25 Bayer Ag Kristallmodifikation III von N-(4-(5-Dimethylamino-naphthalin-1-sulfonyl-amino)-phenyl)-3-hydroxy-2,2-dimethyl-propionamid
EP1402890B1 (en) * 2001-06-08 2008-01-09 Institute of Medicinal Molecular Design, Inc. Sulfonamide derivatives
WO2003086377A1 (fr) * 2002-04-18 2003-10-23 Institute Of Medicinal Molecular Design. Inc. Derives amide
TW200510311A (en) 2002-12-23 2005-03-16 Millennium Pharm Inc CCr8 inhibitors
US7491827B2 (en) 2002-12-23 2009-02-17 Millennium Pharmaceuticals, Inc. Aryl sulfonamides useful as inhibitors of chemokine receptor activity
AU2003303483A1 (en) * 2002-12-23 2004-07-22 Millennium Pharmaceuticals, Inc. Ccr8 inhibitors
US7425527B2 (en) * 2004-06-04 2008-09-16 The Procter & Gamble Company Organic activator
RU2452490C1 (ru) * 2010-12-27 2012-06-10 Виктор Вениаминович Тец Лекарственное средство с активностью против семейства герпес-вирусов
EP2846788A1 (en) 2012-05-11 2015-03-18 Akron Molecules AG Use of compounds for the treatment of pain
RU2530587C1 (ru) 2013-06-07 2014-10-10 Виктор Вениаминович Тец Способ лечения заболеваний кожи и слизистых оболочек, вызываемых вирусами простого герпеса 1-го и 2-го типов
RU2605602C1 (ru) * 2015-09-15 2016-12-27 Общество с ограниченной ответственностью "Новые Антибиотики" Способ получения натриевой соли (2,6-дихлорфенил)амида карбопентоксисульфаниловой кислоты
CN112062901B (zh) * 2020-08-14 2023-03-21 合肥工业大学 一种螺旋荧光异腈共聚物及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2423572A (en) * 1946-05-03 1947-07-08 Du Pont Naphtholsulfonamidobenzaldehydes and acetals thereof
US2949479A (en) * 1954-06-17 1960-08-16 Dainippon Pharmaceutical Co Acyl derivatives of aminonaphthalene-sulfonamide
US3482971A (en) 1967-07-24 1969-12-09 Polaroid Corp Scavengers for oxidized developing agent
US3925347A (en) 1967-07-24 1975-12-09 Polaroid Corp Processes of synthesizing azo compounds
US4035401A (en) 1970-03-30 1977-07-12 Polaroid Corporation Intermediates for photographic dyes
JPS5499433A (en) 1978-01-20 1979-08-06 Konishiroku Photo Ind Co Ltd Dye image formation method
DE3863375D1 (de) 1987-03-19 1991-08-01 Agfa Gevaert Nv Organische verbindungen fuer das farbstoffdiffusionsuebertragungsverfahren und diese verbindungen enthaltende photographische elemente.
JPH04503672A (ja) 1989-02-27 1992-07-02 イー・アイ・デュポン・ドゥ・ヌムール・アンド・カンパニー 放射線増感剤としての新規なナフタレンスルホンアミド
DE4331134A1 (de) * 1993-09-14 1995-03-16 Bayer Ag Neue antiviral wirksame Pseudopeptide
EP0684515A1 (en) 1994-05-27 1995-11-29 Eastman Kodak Company Photographic element and process incorporating a high dye-yield image coupler providing improved granularity

Also Published As

Publication number Publication date
EP1049666B1 (de) 2003-06-04
NO20003601D0 (no) 2000-07-13
SK11012000A3 (sk) 2001-01-18
ES2201666T3 (es) 2004-03-16
EE200000432A (et) 2001-12-17
PE20000181A1 (es) 2000-04-12
IL137159A0 (en) 2001-07-24
NO20003601L (no) 2000-09-14
GT199900010A (es) 2000-07-15
NZ505900A (en) 2002-02-01
HRP20000532A2 (en) 2001-02-28
SV1999000006A (es) 2000-10-09
TR200002140T2 (tr) 2000-12-21
ATE242207T1 (de) 2003-06-15
JP2002501043A (ja) 2002-01-15
DE59905829D1 (de) 2003-07-10
HUP0200918A2 (en) 2002-09-28
ZA99473B (en) 1999-07-27
BR9907738A (pt) 2000-10-17
AU2420799A (en) 1999-08-09
TW461880B (en) 2001-11-01
US6417181B1 (en) 2002-07-09
CA2318182A1 (en) 1999-07-29
EP1049666A1 (de) 2000-11-08
AR016978A1 (es) 2001-08-01
PL341815A1 (en) 2001-05-07
BG104617A (en) 2001-04-30
WO1999037609A1 (de) 1999-07-29
ID25448A (id) 2000-10-05
CN1294578A (zh) 2001-05-09
KR20010034321A (ko) 2001-04-25

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