ES2191284T3 - Derivados de 2-fenoxianilina. - Google Patents
Derivados de 2-fenoxianilina.Info
- Publication number
- ES2191284T3 ES2191284T3 ES98911036T ES98911036T ES2191284T3 ES 2191284 T3 ES2191284 T3 ES 2191284T3 ES 98911036 T ES98911036 T ES 98911036T ES 98911036 T ES98911036 T ES 98911036T ES 2191284 T3 ES2191284 T3 ES 2191284T3
- Authority
- ES
- Spain
- Prior art keywords
- group
- sub
- sup
- alkyl
- alkyl group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 125000003277 amino group Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- NMFFUUFPJJOWHK-UHFFFAOYSA-N 2-phenoxyaniline Chemical class NC1=CC=CC=C1OC1=CC=CC=C1 NMFFUUFPJJOWHK-UHFFFAOYSA-N 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/22—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
- C07C217/86—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/90—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to a carbon atom of a six-membered aromatic ring, e.g. amino-diphenylethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/59—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Abstract
Un derivado de la 2-fenoxianilina representado por la fórmula: * fórmula * en la que R{sup,1} es un átomo de hidrógeno, un grupo amino o un grupo NHCOR{sup,3}, R{sup,2} es un átomo de halógeno, un grupo amino, un grupo ciano, un grupo alquilo C{sub,1-6}, un grupo perfluoroalquilo C{sub,1-3}, un grupo NHCOR{sup,3}, un grupo CH{sub,2}OR{sup,4}, un grupo OCH{sub,2}R{sup,5} o un grupo COR{sup,6}, R{sup,3} es un grupo alquilo C{sub,1-6}, R{sup,4} es un átomo de hidrógeno o un grupo alquilo C{sub,1-6}, R{sup,5} es un átomo de hidrógeno, un grupo alquilo C{sub,1-6}, un grupo aminoalquilo alquilo C{sub,1-5}, un grupo alcoxicarbonilo alquilo C{sub,2-7} o un grupo carbamoílo y R{sup,6} es un grupo alquilo C{sub,1-6} o un grupo cicloalquilo alquilo C{sub,3-8} que puede estar insustituido o sustituido por un átomo de halógeno, un grupo amino, un grupo ciano o un grupo alquilo C{sub,1-6} lineal o ramificado o una de sus sales farmacéuticamente aceptables.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7428897 | 1997-03-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2191284T3 true ES2191284T3 (es) | 2003-09-01 |
Family
ID=13542803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98911036T Expired - Lifetime ES2191284T3 (es) | 1997-03-27 | 1998-03-26 | Derivados de 2-fenoxianilina. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6156801A (es) |
EP (1) | EP0978506B1 (es) |
KR (1) | KR20010005632A (es) |
CN (1) | CN1166623C (es) |
AT (1) | ATE230720T1 (es) |
AU (1) | AU726239B2 (es) |
CA (1) | CA2285553A1 (es) |
DE (1) | DE69810606T2 (es) |
DK (1) | DK0978506T3 (es) |
ES (1) | ES2191284T3 (es) |
HK (1) | HK1026202A1 (es) |
WO (1) | WO1998043943A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI20011507A0 (fi) | 2001-07-10 | 2001-07-10 | Orion Corp | Uusia yhdisteitä |
AU2002336532C1 (en) * | 2001-09-14 | 2008-10-16 | Amgen, Inc | Linked biaryl compounds |
WO2003061700A1 (fr) * | 2002-01-25 | 2003-07-31 | Taisho Pharmaceutical Co.,Ltd. | Medicaments servant au traitement de nephropathies chroniques |
JPWO2003068263A1 (ja) * | 2002-02-15 | 2005-06-02 | 大正製薬株式会社 | 高血圧症治療薬 |
JPWO2004000813A1 (ja) * | 2002-06-25 | 2005-10-20 | アステラス製薬株式会社 | フェノキシピリジン誘導体又はその塩 |
FI20030030A0 (fi) | 2003-01-09 | 2003-01-09 | Orion Corp | Uusia yhdisteitä |
KR101817925B1 (ko) | 2011-09-12 | 2018-01-12 | 사노피 | 치환된 2-(크로만-6-일옥시)-티아졸 및 약제로서의 이의 용도 |
SI2567958T1 (sl) | 2011-09-12 | 2015-01-30 | Sanofi | Substituirani 2-(kroman-6-iloksi)-tiazoli in njihova uporaba kot farmacevtiki |
US8912224B2 (en) | 2011-09-12 | 2014-12-16 | Sanofi | Substituted 2-(chroman-6-yloxy)-thiazoles and their use as pharmaceuticals |
TWI633095B (zh) | 2013-03-08 | 2018-08-21 | 賽諾菲公司 | 經取代-6-基氧基-環烷類及其作為醫藥品之用途 |
WO2019175464A1 (en) | 2018-03-14 | 2019-09-19 | Orion Corporation | Compounds useful as inhibitors of sodium-calcium exchanger (ncx) |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0791248B2 (ja) * | 1988-06-29 | 1995-10-04 | 富士写真フイルム株式会社 | アルコキシもしくはアリールオキシベンゼン化合物の製造方法 |
JPH05194400A (ja) * | 1991-09-20 | 1993-08-03 | Kumiai Chem Ind Co Ltd | イソニコチン酸アニリド誘導体及びこれを含有する農園芸用殺菌剤 |
JP3859738B2 (ja) * | 1993-05-26 | 2006-12-20 | 大日本住友製薬株式会社 | キナゾリノン誘導体 |
EP0626373B1 (en) * | 1993-05-26 | 1998-12-23 | Sumitomo Pharmaceuticals Company, Limited | Quinazolinone derivatives |
-
1998
- 1998-03-26 DE DE69810606T patent/DE69810606T2/de not_active Expired - Lifetime
- 1998-03-26 US US09/381,039 patent/US6156801A/en not_active Expired - Fee Related
- 1998-03-26 CA CA002285553A patent/CA2285553A1/en not_active Abandoned
- 1998-03-26 ES ES98911036T patent/ES2191284T3/es not_active Expired - Lifetime
- 1998-03-26 WO PCT/JP1998/001367 patent/WO1998043943A1/ja not_active Application Discontinuation
- 1998-03-26 EP EP98911036A patent/EP0978506B1/en not_active Expired - Lifetime
- 1998-03-26 AT AT98911036T patent/ATE230720T1/de not_active IP Right Cessation
- 1998-03-26 DK DK98911036T patent/DK0978506T3/da active
- 1998-03-26 AU AU65187/98A patent/AU726239B2/en not_active Ceased
- 1998-03-26 CN CNB988037688A patent/CN1166623C/zh not_active Expired - Fee Related
- 1998-03-26 KR KR1019997008699A patent/KR20010005632A/ko not_active Application Discontinuation
-
2000
- 2000-09-04 HK HK00105533A patent/HK1026202A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69810606D1 (en) | 2003-02-13 |
CN1251571A (zh) | 2000-04-26 |
DK0978506T3 (da) | 2003-02-24 |
EP0978506A1 (en) | 2000-02-09 |
AU726239B2 (en) | 2000-11-02 |
US6156801A (en) | 2000-12-05 |
AU6518798A (en) | 1998-10-22 |
EP0978506A4 (en) | 2000-12-13 |
KR20010005632A (ko) | 2001-01-15 |
CN1166623C (zh) | 2004-09-15 |
HK1026202A1 (en) | 2000-12-08 |
CA2285553A1 (en) | 1998-10-08 |
ATE230720T1 (de) | 2003-01-15 |
DE69810606T2 (de) | 2003-10-09 |
WO1998043943A1 (fr) | 1998-10-08 |
EP0978506B1 (en) | 2003-01-08 |
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