PT83345A - Processo para a preparacao de ypsilon-carbolinas antipsicoticas - Google Patents

Processo para a preparacao de ypsilon-carbolinas antipsicoticas

Info

Publication number
PT83345A
PT83345A PT83345A PT8334586A PT83345A PT 83345 A PT83345 A PT 83345A PT 83345 A PT83345 A PT 83345A PT 8334586 A PT8334586 A PT 8334586A PT 83345 A PT83345 A PT 83345A
Authority
PT
Portugal
Prior art keywords
sup
alkyl
hydrogen
antipsytic
ypsilon
Prior art date
Application number
PT83345A
Other languages
English (en)
Other versions
PT83345B (pt
Inventor
Magid Abdel-Megid Abou-Gharbia
Usha Rajni Patel
Reinhardt Peter Stein
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of PT83345A publication Critical patent/PT83345A/pt
Publication of PT83345B publication Critical patent/PT83345B/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT83345A 1985-09-16 1986-09-10 Processo para a preparacao de gama-carbolinas antipsicoticas PT83345B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,349 US4672117A (en) 1985-09-16 1985-09-16 Antipsychotic gamma-carbolines

Publications (2)

Publication Number Publication Date
PT83345A true PT83345A (pt) 1986-10-01
PT83345B PT83345B (pt) 1988-07-29

Family

ID=25107141

Family Applications (1)

Application Number Title Priority Date Filing Date
PT83345A PT83345B (pt) 1985-09-16 1986-09-10 Processo para a preparacao de gama-carbolinas antipsicoticas

Country Status (15)

Country Link
US (1) US4672117A (pt)
EP (1) EP0222474B1 (pt)
JP (1) JPS6270374A (pt)
KR (1) KR900002246B1 (pt)
AT (1) ATE57184T1 (pt)
AU (1) AU583941B2 (pt)
CA (1) CA1275100A (pt)
DE (1) DE3674721D1 (pt)
DK (1) DK440486A (pt)
ES (1) ES2002617A6 (pt)
GB (1) GB2180535B (pt)
GR (1) GR862344B (pt)
HU (1) HU194564B (pt)
PT (1) PT83345B (pt)
ZA (1) ZA866259B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
WO1995018092A1 (fr) * 1993-12-28 1995-07-06 Maruho Co., Ltd. Derive de l'aminocetone
EP0905136A1 (en) 1997-09-08 1999-03-31 Janssen Pharmaceutica N.V. Tetrahydro gamma-carbolines
JP2004015286A (ja) * 2002-06-05 2004-01-15 Seiko Epson Corp ディジタルカメラ
MXPA06011777A (es) 2004-04-12 2007-01-16 Taisho Pharma Co Ltd Compuesto de amina ciclico.
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
BRPI0815850A2 (pt) * 2007-08-01 2014-10-07 Medivation Neurology Inc "método para tratar, retardar a progressão, prevenir ou atrasar o desenvolvimento de esquizofrenia em um individuo, composiçã farmaceuticamente aceitável, kit e método para reforçar uma resposta de um individuo a um antipsicótico"

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522262A (en) * 1968-09-10 1970-07-28 Hoffmann La Roche 5-(pyridylalkyl)-pyridoindole derivatives
US3502688A (en) * 1968-09-10 1970-03-24 Hoffmann La Roche 5-(4-pyridylethyl)-pyridoindole derivatives
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
GB2209335B (en) * 1987-09-03 1991-05-29 Glaxo Group Ltd Lactam derivatives

Also Published As

Publication number Publication date
GB8621225D0 (en) 1986-10-08
ES2002617A6 (es) 1988-09-01
ATE57184T1 (de) 1990-10-15
AU6181486A (en) 1987-03-19
HUT42480A (en) 1987-07-28
HU194564B (en) 1988-02-29
EP0222474A1 (en) 1987-05-20
GR862344B (en) 1987-01-12
ZA866259B (en) 1988-03-30
KR900002246B1 (ko) 1990-04-07
AU583941B2 (en) 1989-05-11
JPS6270374A (ja) 1987-03-31
DE3674721D1 (en) 1990-11-08
KR870003104A (ko) 1987-04-15
GB2180535A (en) 1987-04-01
EP0222474B1 (en) 1990-10-03
DK440486D0 (da) 1986-09-15
GB2180535B (en) 1989-04-05
CA1275100A (en) 1990-10-09
US4672117A (en) 1987-06-09
DK440486A (da) 1987-03-17
PT83345B (pt) 1988-07-29

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Legal Events

Date Code Title Description
MM3A Annulment or lapse

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Effective date: 19940731