GR862344B - Antipsychotic g-carbolines - Google Patents

Antipsychotic g-carbolines

Info

Publication number
GR862344B
GR862344B GR862344A GR860102344A GR862344B GR 862344 B GR862344 B GR 862344B GR 862344 A GR862344 A GR 862344A GR 860102344 A GR860102344 A GR 860102344A GR 862344 B GR862344 B GR 862344B
Authority
GR
Greece
Prior art keywords
sup
alkyl
hydrogen
antipsychotic
halogen
Prior art date
Application number
GR862344A
Other languages
English (en)
Inventor
M A Abou-Charbia
U R Patel
R P Stein
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of GR862344B publication Critical patent/GR862344B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR862344A 1985-09-16 1986-09-12 Antipsychotic g-carbolines GR862344B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/776,349 US4672117A (en) 1985-09-16 1985-09-16 Antipsychotic gamma-carbolines

Publications (1)

Publication Number Publication Date
GR862344B true GR862344B (en) 1987-01-12

Family

ID=25107141

Family Applications (1)

Application Number Title Priority Date Filing Date
GR862344A GR862344B (en) 1985-09-16 1986-09-12 Antipsychotic g-carbolines

Country Status (15)

Country Link
US (1) US4672117A (el)
EP (1) EP0222474B1 (el)
JP (1) JPS6270374A (el)
KR (1) KR900002246B1 (el)
AT (1) ATE57184T1 (el)
AU (1) AU583941B2 (el)
CA (1) CA1275100A (el)
DE (1) DE3674721D1 (el)
DK (1) DK440486A (el)
ES (1) ES2002617A6 (el)
GB (1) GB2180535B (el)
GR (1) GR862344B (el)
HU (1) HU194564B (el)
PT (1) PT83345B (el)
ZA (1) ZA866259B (el)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636563A (en) * 1985-09-16 1987-01-13 American Home Products Corporation Antipsychotic γ-carbolines
US5360800A (en) * 1987-09-03 1994-11-01 Glaxo Group Limited Tetrahydro-1H-pyrido[4,3-b]indol-1-one derivatives
US4798896A (en) * 1988-01-19 1989-01-17 American Home Products Corporation Antipsychotic gamma-carboline N-oxides
HU207078B (en) * 1988-08-02 1993-03-01 Glaxo Group Ltd Process for producing lactam derivatives and pharmaceutical compositions comprising such compounds
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
WO1995018092A1 (fr) * 1993-12-28 1995-07-06 Maruho Co., Ltd. Derive de l'aminocetone
EP0905136A1 (en) 1997-09-08 1999-03-31 Janssen Pharmaceutica N.V. Tetrahydro gamma-carbolines
JP2004015286A (ja) * 2002-06-05 2004-01-15 Seiko Epson Corp ディジタルカメラ
MXPA06011777A (es) * 2004-04-12 2007-01-16 Taisho Pharma Co Ltd Compuesto de amina ciclico.
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
KR20100054812A (ko) * 2007-08-01 2010-05-25 메디베이션 뉴롤로지 인코퍼레이티드 항정신병제 조합 치료제를 사용하여 정신분열증을 치료하기 위한 방법 및 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3522262A (en) * 1968-09-10 1970-07-28 Hoffmann La Roche 5-(pyridylalkyl)-pyridoindole derivatives
US3502688A (en) * 1968-09-10 1970-03-24 Hoffmann La Roche 5-(4-pyridylethyl)-pyridoindole derivatives
US4001263A (en) * 1974-04-01 1977-01-04 Pfizer Inc. 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents
NZ226032A (en) * 1987-09-03 1991-12-23 Glaxo Group Ltd 2-(imidazolylmethyl)-pyrido or-azepino(4,3-b)indole-1(2h)-one derivatives; preparatory processes and pharmaceutical compositions

Also Published As

Publication number Publication date
AU6181486A (en) 1987-03-19
GB8621225D0 (en) 1986-10-08
EP0222474B1 (en) 1990-10-03
DE3674721D1 (en) 1990-11-08
KR870003104A (ko) 1987-04-15
PT83345B (pt) 1988-07-29
ATE57184T1 (de) 1990-10-15
CA1275100A (en) 1990-10-09
GB2180535B (en) 1989-04-05
HUT42480A (en) 1987-07-28
EP0222474A1 (en) 1987-05-20
PT83345A (pt) 1986-10-01
DK440486D0 (da) 1986-09-15
ES2002617A6 (es) 1988-09-01
JPS6270374A (ja) 1987-03-31
GB2180535A (en) 1987-04-01
US4672117A (en) 1987-06-09
ZA866259B (en) 1988-03-30
KR900002246B1 (ko) 1990-04-07
DK440486A (da) 1987-03-17
HU194564B (en) 1988-02-29
AU583941B2 (en) 1989-05-11

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