NO20002696D0 - Nye forbindelser med cGMP-PDE-inhibitoreffekt - Google Patents

Nye forbindelser med cGMP-PDE-inhibitoreffekt

Info

Publication number
NO20002696D0
NO20002696D0 NO20002696A NO20002696A NO20002696D0 NO 20002696 D0 NO20002696 D0 NO 20002696D0 NO 20002696 A NO20002696 A NO 20002696A NO 20002696 A NO20002696 A NO 20002696A NO 20002696 D0 NO20002696 D0 NO 20002696D0
Authority
NO
Norway
Prior art keywords
cgmp
new compounds
pde inhibitor
inhibitor effect
effect
Prior art date
Application number
NO20002696A
Other languages
English (en)
Other versions
NO20002696L (no
Inventor
Masayuki Ohashi
Hidemitsu Nishida
Toshiyuki Shudo
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NO20002696D0 publication Critical patent/NO20002696D0/no
Publication of NO20002696L publication Critical patent/NO20002696L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/06Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20002696A 1997-11-28 2000-05-26 Nye forbindelser med cGMP-PDE-inhibitoreffekt NO20002696L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34416497 1997-11-28
PCT/JP1998/005350 WO1999028319A1 (fr) 1997-11-28 1998-11-27 NOUVEAUX COMPOSES PRESENTANT UN EFFET INHIBITEUR DE cGMP-PDE

Publications (2)

Publication Number Publication Date
NO20002696D0 true NO20002696D0 (no) 2000-05-26
NO20002696L NO20002696L (no) 2000-07-24

Family

ID=18367131

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20002696A NO20002696L (no) 1997-11-28 2000-05-26 Nye forbindelser med cGMP-PDE-inhibitoreffekt

Country Status (14)

Country Link
US (1) US6476021B1 (no)
EP (1) EP1048666A4 (no)
KR (1) KR20010032546A (no)
CN (1) CN1284075A (no)
AU (1) AU746883B2 (no)
BR (1) BR9815070A (no)
CA (1) CA2311947A1 (no)
HU (1) HUP0100083A3 (no)
IL (1) IL136340A0 (no)
MX (1) MXPA00005190A (no)
NO (1) NO20002696L (no)
PL (1) PL340789A1 (no)
WO (1) WO1999028319A1 (no)
ZA (1) ZA9810766B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2335809A1 (en) 1998-06-23 1999-12-29 Glaxo Group Limited 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
AU5204800A (en) * 1999-06-21 2001-01-09 Biochemical Pharmaceutical Factory of Zhuhai Sez, The Process for preparing sildenafil, and troche which comprises sildenafil and apomorphine
DE19954707A1 (de) * 1999-11-13 2001-05-17 Merck Patent Gmbh Imidazolverbindungen als Phosphodiesterase VII-Hemmer
IL151695A0 (en) 2000-03-15 2003-04-10 Aventis Pharma Gmbh Substituted beta-carbolines with ikb-kinase inhibiting activity
WO2001068648A1 (en) * 2000-03-15 2001-09-20 Aventis Pharma Deutschland Gmbh Substituted beta-carbolines with ikb-kinase inhibiting activity
CA2407031A1 (en) 2000-04-19 2001-10-25 Lilly Icos Llc Use of cyclic gmp-specific phosphodiesterase inhibitors for treatment of parkinson's disease
US6271228B1 (en) * 2000-04-28 2001-08-07 Pfizer Inc. Blood pressure stabilization during hemodialysis
UA80258C2 (en) * 2001-09-06 2007-09-10 Biogen Inc Methods of treating pulmonary disease
US20050107394A1 (en) * 2001-12-17 2005-05-19 Ardeschir Ghofrani Novel use of selective pde5 inhibitors
GB0202254D0 (en) * 2002-01-31 2002-03-20 Pfizer Ltd Prevention of scarring
US8133903B2 (en) 2003-10-21 2012-03-13 Los Angeles Biomedical Research Institute at Harbor—UCLA Medical Center Methods of use of inhibitors of phosphodiesterases and modulators of nitric oxide, reactive oxygen species, and metalloproteinases in the treatment of peyronie's disease, arteriosclerosis and other fibrotic diseases
US7601856B2 (en) * 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) * 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
CN115872991A (zh) * 2021-09-26 2023-03-31 深圳大学 β-咔伯啉生物碱类化合物及其药用组合物、制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS261338B1 (cs) * 1987-09-17 1989-06-15 Viktor Zikan Způsob přípravy 10-nitro-4-oxo-4H-chino/2,3,4-i,j//1,4/benzoxazinových derivátů
GB9126260D0 (en) * 1991-12-11 1992-02-12 Pfizer Ltd Therapeutic agents
JPH0710843A (ja) * 1993-03-31 1995-01-13 Eisai Co Ltd 含窒素縮合複素環化合物
PH31122A (en) * 1993-03-31 1998-02-23 Eisai Co Ltd Nitrogen-containing fused-heterocycle compounds.
DE69533057T2 (de) * 1994-08-09 2005-06-16 Eisai Co., Ltd. Kondensierte pyridazinverbindungen
GB9423910D0 (en) * 1994-11-26 1995-01-11 Pfizer Ltd Therapeutic agents
JP3713783B2 (ja) * 1995-01-20 2005-11-09 大正製薬株式会社 1H−ピラゾロ[3,4−d]ピリミジン−4−オン誘導体
EP0985671B1 (en) * 1996-05-31 2003-04-02 Mochida Pharmaceutical Co., Ltd. PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT
BR9809508A (pt) * 1997-05-29 2000-06-20 Mochida Pharm Co Ltd Agente terapêutico para disfunção de ereção
AU5067098A (en) * 1997-11-26 1999-06-15 Mochida Pharmaceutical Co., Ltd. Pyridocarbazole derivatives with cgmp-pde inhibitory activity

Also Published As

Publication number Publication date
HUP0100083A3 (en) 2002-01-28
HUP0100083A2 (hu) 2001-08-28
BR9815070A (pt) 2000-10-03
NO20002696L (no) 2000-07-24
ZA9810766B (en) 1999-05-25
EP1048666A1 (en) 2000-11-02
MXPA00005190A (es) 2002-04-24
EP1048666A4 (en) 2001-10-31
CA2311947A1 (en) 1999-06-10
CN1284075A (zh) 2001-02-14
AU746883B2 (en) 2002-05-02
WO1999028319A1 (fr) 1999-06-10
PL340789A1 (en) 2001-02-26
AU1261799A (en) 1999-06-16
US6476021B1 (en) 2002-11-05
IL136340A0 (en) 2001-05-20
KR20010032546A (ko) 2001-04-25

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application