CO4520185A1 - Procedimiento para el desdoblamiento de los racematos del tramadol - Google Patents

Procedimiento para el desdoblamiento de los racematos del tramadol

Info

Publication number
CO4520185A1
CO4520185A1 CO96068520A CO96068520A CO4520185A1 CO 4520185 A1 CO4520185 A1 CO 4520185A1 CO 96068520 A CO96068520 A CO 96068520A CO 96068520 A CO96068520 A CO 96068520A CO 4520185 A1 CO4520185 A1 CO 4520185A1
Authority
CO
Colombia
Prior art keywords
tramadol
unfolding
procedure
racematos
del
Prior art date
Application number
CO96068520A
Other languages
English (en)
Spanish (es)
Inventor
Helmut Buschmann
Werner Winter
Graudums Ivars
Peter Jansen
Original Assignee
Gruenenthal Chemie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Chemie filed Critical Gruenenthal Chemie
Publication of CO4520185A1 publication Critical patent/CO4520185A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CO96068520A 1996-01-19 1996-12-30 Procedimiento para el desdoblamiento de los racematos del tramadol CO4520185A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601745A DE19601745C1 (de) 1996-01-19 1996-01-19 Verfahren zur Racematspaltung von Tramadol

Publications (1)

Publication Number Publication Date
CO4520185A1 true CO4520185A1 (es) 1997-10-15

Family

ID=7783112

Family Applications (1)

Application Number Title Priority Date Filing Date
CO96068520A CO4520185A1 (es) 1996-01-19 1996-12-30 Procedimiento para el desdoblamiento de los racematos del tramadol

Country Status (31)

Country Link
US (1) US5723668A (enExample)
EP (1) EP0787715B1 (enExample)
JP (1) JPH09216858A (enExample)
KR (1) KR100505527B1 (enExample)
CN (1) CN1131203C (enExample)
AR (1) AR005391A1 (enExample)
AT (1) ATE189205T1 (enExample)
AU (1) AU711750B2 (enExample)
BR (1) BR9700094A (enExample)
CA (1) CA2195370C (enExample)
CO (1) CO4520185A1 (enExample)
CZ (1) CZ291775B6 (enExample)
DE (2) DE19601745C1 (enExample)
DK (1) DK0787715T3 (enExample)
ES (1) ES2145373T3 (enExample)
GR (1) GR3032489T3 (enExample)
HU (1) HU223067B1 (enExample)
IL (1) IL120028A (enExample)
IN (1) IN182218B (enExample)
MY (1) MY116583A (enExample)
NO (1) NO306059B1 (enExample)
NZ (1) NZ299999A (enExample)
PE (1) PE29898A1 (enExample)
PL (1) PL187403B1 (enExample)
PT (1) PT787715E (enExample)
RU (1) RU2192407C2 (enExample)
SI (1) SI0787715T1 (enExample)
SK (1) SK281612B6 (enExample)
UA (1) UA45343C2 (enExample)
UY (1) UY24439A1 (enExample)
ZA (1) ZA97369B (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2130079B1 (es) * 1997-07-10 2000-01-16 Esteve Labor Dr Resolucion de aminas
CA2295884A1 (en) 1997-07-15 1999-01-28 Russinsky Limited Tramadol, salts thereof and process for their preparation
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
GB9826540D0 (en) 1998-12-02 1999-01-27 Darwin Discovery Ltd Process
KR100342919B1 (ko) * 1999-10-21 2002-07-04 박노중 트랜스체 염산 트라마돌의 분리 제조방법
CA2423558A1 (en) * 2000-10-03 2002-04-11 Penwest Pharmaceuticals Company Delivery system for multi-pharmaceutical active materials at various release rates
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
CA2758923A1 (en) 2001-03-16 2002-09-26 Dmi Biosciences, Inc. Use of tramadol to delay ejaculation
US6649783B2 (en) * 2001-10-03 2003-11-18 Euro-Celtique, S.A. Synthesis of (+/-)-2-((dimethylamino)methyl)-1-(aryl)cyclohexanols
US6780891B2 (en) 2001-11-30 2004-08-24 Sepracor Inc. Tramadol analogs and uses thereof
US20040248979A1 (en) * 2003-06-03 2004-12-09 Dynogen Pharmaceuticals, Inc. Method of treating lower urinary tract disorders
CN101151248B (zh) 2005-01-26 2012-06-20 阿勒根公司 具有镇痛活性和/或免疫刺激物活性的3-芳基-3-羟基-2-氨基丙酸酰胺类、3-杂芳基-3-羟基-2-氨基丙酸酰胺类以及相关化合物
EP1785412A1 (en) 2005-11-14 2007-05-16 IPCA Laboratories Limited Tramadol recovery process
NZ579170A (en) 2007-02-12 2012-05-25 Dmi Biosciences Inc Reducing side effects of tramadol
BRPI0807282A2 (pt) 2007-02-12 2014-04-29 Dmi Biosciences Inc Tratamento de ejaculação precoce e disfunção erétil co-mórbidas
DE102013009114A1 (de) 2013-05-29 2014-12-04 Franz Gerstheimer Pharmazeutische Zusammensetzung zur Überwindung von Metabolisierungsproblemen
KR102136004B1 (ko) 2018-06-18 2020-07-22 (주)센텍코리아 감지부의 잔존 수명을 추정할 수 있는 음주측정기

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528267A (en) * 1950-10-31 Eobeet j
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
IL50080A (en) * 1975-07-29 1979-07-25 Beecham Group Ltd 4-oxa-1-azabicyclo(3.2.0)heptan-7-one-2-car boxylic acid derivatives and their preparation
GB9017390D0 (en) * 1990-08-08 1990-09-19 Norgine Ltd Improvements in or relating to propylamine derivatives
JPH06122686A (ja) * 1992-10-12 1994-05-06 Fujisawa Pharmaceut Co Ltd ラセミ体の光学分割法

Also Published As

Publication number Publication date
RU2192407C2 (ru) 2002-11-10
DE19601745C1 (de) 1997-10-09
CN1131203C (zh) 2003-12-17
PL318003A1 (en) 1997-07-21
AU711750B2 (en) 1999-10-21
ES2145373T3 (es) 2000-07-01
IN182218B (enExample) 1999-02-06
IL120028A (en) 1999-12-22
NO970211D0 (no) 1997-01-17
EP0787715A1 (de) 1997-08-06
NO970211L (no) 1997-07-21
PE29898A1 (es) 1998-08-08
AU1223297A (en) 1997-07-24
UA45343C2 (uk) 2002-04-15
DE59604295D1 (de) 2000-03-02
HUP9700141A3 (en) 2000-03-28
PT787715E (pt) 2000-06-30
CZ291775B6 (cs) 2003-05-14
GR3032489T3 (en) 2000-05-31
IL120028A0 (en) 1997-04-15
ATE189205T1 (de) 2000-02-15
SK6897A3 (en) 1997-08-06
UY24439A1 (es) 1997-01-30
JPH09216858A (ja) 1997-08-19
CN1161957A (zh) 1997-10-15
CZ15697A3 (cs) 1998-05-13
MY116583A (en) 2004-02-28
NO306059B1 (no) 1999-09-13
SI0787715T1 (en) 2000-04-30
BR9700094A (pt) 1998-09-22
ZA97369B (en) 1997-07-29
NZ299999A (en) 1998-01-26
AR005391A1 (es) 1999-04-28
CA2195370A1 (en) 1997-07-20
DK0787715T3 (da) 2000-04-25
SK281612B6 (sk) 2001-05-10
HUP9700141A2 (hu) 1998-01-28
KR970059155A (ko) 1997-08-12
PL187403B1 (pl) 2004-07-30
CA2195370C (en) 2005-07-12
EP0787715B1 (de) 2000-01-26
KR100505527B1 (ko) 2005-10-19
HU9700141D0 (en) 1997-03-28
HU223067B1 (hu) 2004-03-01
US5723668A (en) 1998-03-03
MX9700483A (es) 1997-07-31

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