CO4410392A1 - Benzoxazolil- y benzotiazoliloxazolidinonas - Google Patents
Benzoxazolil- y benzotiazoliloxazolidinonasInfo
- Publication number
- CO4410392A1 CO4410392A1 CO95034777A CO95034777A CO4410392A1 CO 4410392 A1 CO4410392 A1 CO 4410392A1 CO 95034777 A CO95034777 A CO 95034777A CO 95034777 A CO95034777 A CO 95034777A CO 4410392 A1 CO4410392 A1 CO 4410392A1
- Authority
- CO
- Colombia
- Prior art keywords
- alkyl
- substd
- opt
- alkoxy
- acyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
1. COMPUESTOS DE LA FORMULA GENERAL (I) EN LA CUAL A REPRESENTA UN ATOMO DE OXIGENO O UN RESTO DE FORMULA -S(O)a, EN DONDE a SIGNIFICA UN NUMERO 0 o 2 R1 REPRESENTA ACIDO O REPRESENTA UN GRUPO DE FOR- MULA 0-SO2R3 o NR4R5, EN DONDE R3 SIGNIFICA ALQUILO, LINEAL O RAMIFICADO, CON HASTA 4 ATOMOS DE CARBONO O FENILO QUE, DADO EL CASO, ESTA SUSTITUIDO POR ALQUILO, LINEAL O RAMI- FICADO, CON HASTA 4 ATOMOS DE CARBONO, R4 Y R5 SON IGUALES O DISTINTOS Y SIGNIFICAN CI- CLOALQUILO CON 3 A 6 ATOMOS DE CARBONO, HIDROGENO, FENILO O ALQUILO LINEAL O RAMIFICADO, CON HASTA 8 ATOMOS DE CARBONO O UN GRUPO PROTECTOR DE AMINO, o R4 o R5 SIGNIFICAN UN GRUPO DE FORMULA -CO-R6, EN DONDE R6 SIGNIFICA CICLOALQUILO CON 3 A 6 ATOMOS DE CARBONO, ALQUILO O ALCOXI, LINEAL O RAMIFICADO, CON HASTA 8 ATOMOS DE CARBONO RESPECTIVAMENTE, FENILO O HIDROGENO, G, L, y M SON IGUALES O DISTINTOS Y REPRESENTAN HIDROGENO, CARBOXI, HALOGENO, CIANO, FORMILO, TRIFLUORMETILO, NITRO, ALCOXI, ALCOXICARBONILO, ALQUILTIO O ACILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE, O REPRESENTAN ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO POR HIDROXILO, POR ALCOXI O ACILO, LINEAL O RAMI- FICADO, CON HASTA 5 ATOMOS DE CARBONO O POR UN GRUPO DE FORMULA -NR7R8, EN DONDE R7 yR8 SON IGUALES O DISTINTOS Y SIGNIFICAN HIDRO- GENO, ALQUILO, LINEAL O RAMIFICADO, CON HASTA 4 A- TOMOS DE CARBONO O FENILO, O, JUNTO CON EL ATOMO DE NITROGENO FORMAN UN HETEROCICLO SATURADO DE 5 A 6 ESLABONES, DADO EL CASO CON OTRO HETEROATOMO DEL GRUPO N, S y Y/U O QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO TAMBIEN, DADO EL CASO, EN OTRO ATOMO DE NITROGENO POR ALQUILO O ACILO, LINEAL O RAMIFICA- DO, CON HASTA 3 ATOMOS DE CARBONO, Y/O REPRESENTA, DADO EL CASO, UN GRUPO DE FORMULA -NR7´R8´, EN DONDE, R7´ y R8´ SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R7 y R8 Y SON I- GUALES O DISTINTOS A ESTOS. Y/O REPRESENTAN, DADO EL CASO, (C2-C8)-ALQUENIL-FENI- LO, FENILO O A TRAVES DE UN HETEROCICLO SATURADO O INSATURADO DE 5 o 6 ESLABONES, CON HASTA 3 HETERO- ATOMOS DEL GRUPO S, N y/u O, QUE, POR SU PARTE, ESTAN SUSTITUIDOS, DADO EL CASO, POR UN GRUPO DE FORMULA -CO-NR9R10, NR11R12, NR13-SO2-R14, R15R16N-SO2- o R17-S(O)b- EN DONDE b SIGNIFICA UN NUMERO 0, 1 o 2, R9, R10, R13, R15 y R16 SON IGUALES O DISTINTOS Y SIGNIFICAN HIDROGENO, ALQUILO, LINEAL O RAMIFICA- DO, CON HASTA 6 ATOMOS DE CARBONO O FENILO, R11 y R12 SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R7 y R8 Y SON I- GUALES O DISTINTOS A ESTOS, R14 y R17 SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R3 Y SON IGUALES O DISTINTOS A ESTE, Y/O POR SU PARTE, DADO EL CASO, ESTAN HASTA BISUS- TITUIDOS, POR SUSTITUYENTES IGUALES O DISTINTOS CARBOXI, HALOGENO, CIANO, FORMILO, TRIFLUORMETILO, NITRO, FENILO, ALCOXI. ALCOXICARBONILO, ALQUILTIO O ACILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE, O POR ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO POR HIDROXILO, ALCOXI O ACILO, LINEAL O RAMIFICADO, CON HASTA 5 ATOMOS DE CARBONO O POR UN GRUPO DE FORMULA -NR18R19, EN DONDE R18 Y R19 TIENEN EL SIGNIFICADO INDICADO MAS ARRI- BA PARA R7 y R8 Y SON IGUALES O DISTINTOS A ESTOS, R2 REPRESENTA HIDROGENO, FORMILO, CARBOXI, REPRE- SENTA ALCOXICARBONILO LINEAL O RAMIFICADO CON HAS- TA 6 ATOMOS DE CARBONO, O REPRESENTA ALQUILO O AL- QUENILO, LINEAL O RAMIFICADO, CON HASTA 8 ATOMOS DE CARBONO RESPECTIVAMENTE QUE, DADO EL CASO, ES- TAN SUSTITUIDOS POR HIDROXILO, HALOGENO O POR AL- COXI, ACILO, ALQUILTIO O ALCOXICARBONILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPEC- TIVAMENTE O POR FENILO QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO POR HALOGENO, O REPRESENTA ARILO CON 6 A 10 ATOMOS DE CARBONO QUE DADO, EL CASO, ESTA SUSTITUIDO POR CARBOXI, HALOGENO, CIANO, FOR- MILO, TRIFLUORMETILO, NITRO, ALCOXI, ALCOXICARBO- NILO, ALQUILTIO O ACILO, LINEAL O RAMIFICADO, RA- MIFICADO CON HASTA 6 ATOMOS DE CARBONO RESPECTIVA- MENTE, O POR ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO, O REPRESENTA UN RESTO DE FOR- MULA -NR20R21, -OR22 o -S(O)c-R23, EN DONDE R20 SIGNIFICA CICLOALQUILO CON 3 A 6 ATOMOS DE CARBONO, FENILO, ACILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO O ALQUILO LINEAL O RAMI- FICADO CON HASTA 8 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR HIDROXILO, ALCOXI O AL- COXI SUSTITUIDO POR HIDROXILO, LINEAL O RAMIFICA- DO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE, POR UN HETEROCICLO AROMATICO DE 5 A 6 ESLABONES CON HASTA 3 HETEROATOMOS DEL GRUPO S, N, y/u O, O POR FENILO QUE, POR SU PARTE, PUEDE ESTAR SUSTITU- IDO POR HIDROXILO, TRIFLUORMETILO, HALOGENO, NITRO O POR ALCOXI LINEAL O RAMIFICADO CON HASTA 4 ATO- MOS DE CARBONO, O ALQUILO QUE, DADO EL CASO, ESTA SUSTITUIDO POR UN RESTO DE FORMULA -NR24R25 o FIGURA 1 EN DONDE R24 y R25 SON IGUALES O DISTINTOS Y SIGNIFICAN HI- DROGENO O ALQUILO LINEAL O RAMIFICADO CON HASTA 4 ATOMOS DE CARBONO, O R20 SIGNIFICA UN RESTO DE FORMULA FIGURA 2 EN DONDE R26 SIGNIFICA HIDROXILO, ALCOXI LINEAL O RAMIFICA- DO CON HASTA 4 ATOMOS DE CARBONO, O UN RESTO DE FORMULA -NR28R29, DONDE R28 y R29 SON IGUALES O DISTINTOS Y SIGNIFICAN HIDROGENO O ALQUILO LINEAL O RAMIFICADO CON HASTA 5 ATOMOS DE CARBONO, CICLO- ALQUILO CON 3 A 6 ATOMOS DE CARBONO O FENILO, R27 SIGNIFICA HIDROGENO O ALQUILO LINEAL O RAMIFI- CADO CON HASTA 7 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR INDOLILO, HIDROXILO, MERCAPTILO, IMIDAZOLILO, METILTIO, AMINO, FENILO, FENILO SUSTITUIDO POR HIDROXILO O POR UN RESTO DE FORMULA -CO-HN2, -CO2H NH=C- NH2 R20 SIGNIFICA UN RESTO DE FORMULA FIGURA 3 EN DONDE d SIGNIFICA UN NUMERO O, 1, 2, 3, 4, 5 o 6. T SIGNIFICA UN ATOMO DE OXIGENO O UN GRUPO DE FOR- MULA CH2 o -NR30, EN DONDE R30 SIGNIFICA HIDROGENO, FENILO O ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR HIDROXILO, Y R21 TIENE EL SIGNIFICADO INDICADO MAS ARRIBA PARA R20 Y ES IGUAL O DISTINTOS A ESTE, O SIGNIFICA HI- DROGENO, R22 SIGNIFICA ALQUILO LINEAL O RAMIFICADO CON HAS- TA 8 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR ALCOXI O ALCOXI SUSTITUIDO POR HI- DROXILO O ALCOXI, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE, CICLOALQUILO CON 3 A 6 ATOMOS DE CARBONO O UN HETEROCICLO ARO- MATICO DE 6 ESLABONES, DADO EL CASO, BENZOCONDEN- SADO CON HASTA 4 ATOMOS DE NITROGENO, EL CUAL, POR SU PARTE, PUEDE ESTAR HASTA BISUSTI- TUIDO POR SUSTITUYENTES IGUALES O DISTINTOS NITRO, TRIFLUORMETILO, HALOGENO, CIANO, HIDROXILO O POR ALQUILO, ALCOXI O ACILO, LINEAL O RAMIFICADO, CON HASTA 5 ATOMOS DE CARBONO RESPECTIVAMENTE, R22 SIGNIFICA UN RESTO DE FORMULA FIGURA 4 EN DONDE e TIENE EL SIGNIFICADO INDICADO MAS ARRIBA PARA d Y ES IGUAL O DISTINTO A ESTE, w TIENE EL SIGNIFICADO INDICADO MAS ARRIBA PARA T Y ES IGUAL O DISTINTO A ESTE, O R22 SIGNIFICA FENILO O PIRIDILO, c SIGNIFICA UN NUMERO 0, 1 o 2, R23 SIGNIFICA ALQUILO O ALQUENILO, LINEAL O RAMI- FICADO, CON HASTA 16 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR ALCOXICARBONILO, LI- NEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO O FENILO POR UN HETEROCICLO AROMATICO DE 5 A 7 ESLA- BONES CON HASTA 3 HETEROATOMOS DEL GRUPO S, N u O, o SIGNIFICA ARILO CON 6 A 10 ATOMOS DE CARBONO O UN HETEROCICLO AROMATICO DE 5 A 7 ESLABONES CON HASTA 3 HETEROATOMOS DEL GRUPO S, N u O, Y EN DONDE LOS CICLOS INDICADOS MAS ARRIBA ESTAN HASTA BISUSTITUIDOS, DADO EL CASO, POR SUSTITUYEN- TES IGUALES O DISTINTOS CARBOXI, HALOGENO, CIANO, FORMILO, TRIFLUORMETILO, NITRO, ALCOXI, ALCOXICAR- BONILO, ALQUILTIO O ACILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE O POR ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO O R2 REPRESENTA MORFOLINILO O UN RESTO DE FORMULA FIGURA 5 EN DONDE R31 y R32 TIENEN EL SIGNIFICAOD INDICADO MAS ARRI- BA PARA R24 y R25 Y SON IGUALES O DISTINTOS A ES- TOS, R33 y R34 FORMAN JUNTOS UN RESTO DE FORMULA = O u R33 y R34 SON IGUALES O DISTINTOS Y SIGNIFICAN HI- DROGENO, HIDROXILO O ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, DADO EL CASO, ESTA SUSTITUIDO POR UN GRUPO DE FORMULA -NR41R42, EN DONDE R41 y R42 TIENEN EL SIGNIFICADO INDICADO MAS ARRI- BA PARA R24 y R25 Y SON IGUALES O DISTINTOS A ES- TOS, f SIGNIFICA UN NUMERO 0 o 1 g SIGNIFICA UN NUMERO 0, 1, 2, 3, 4, 5 o 6, R35 SIGNIFICA ARILO CON 6 A 10 ATOMOS DE CARBONO O UN HETEROCICLO AROMATICO DE 5 A 6 ESLABONES, DADO EL CASO TAMBIEN BENZOCONDENSADO, CON HASTA 3 HETE- ROATOMOS DEL GRUPO S, N, y/u O, PUDIENDO ESTAR HASTA TRISUSTITUIDOS TODOS LOS SISTEMAS ANULARES, POR SUSTITUYENTES IGUALES O DISTINTOS NITRO, CIA- NO, HIDROXILO, FENILO, HALOGENO, TRIFLUORMETILO O POR ALQUILO, ALCOXI O ACILO, LINEAL O RAMIFICADO, CON HASTA 5 ATOMOS DE CARBONO RESPECTIVAMENTE, O R35 SIGNIFICA MORFOLINILO, HIDROXILO, ALCOXI, LI- NEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO O UN RESTO DE FORMULA FIGURA 6 EN DONDE R43 y R44 SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R24 y R25, R45 SIGNIFICA MORFOLINILO, HIDROXILO O R36 y R37 SON IGUALES O DISTINTOS Y SIGNIFICAN HI- DROGENO, FENILO O ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO O BENCILO, R38, R39 y R40 SON IGUALES O DISTINTOS Y TIENEN EL SIGNIFICADO INDICADO MAS ARRIBA PARA R30 Y SON I- GUALES O DISTINTOS A ESTE, 1 SIGNIFICA UN NUMERO 1 o 2, Y SUS SALES.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4427475 | 1994-08-03 | ||
| DE19514313A DE19514313A1 (de) | 1994-08-03 | 1995-04-18 | Benzoxazolyl- und Benzothiazolyloxazolidinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4410392A1 true CO4410392A1 (es) | 1997-01-09 |
Family
ID=25938925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95034777A CO4410392A1 (es) | 1994-08-03 | 1995-08-03 | Benzoxazolil- y benzotiazoliloxazolidinonas |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5529998A (es) |
| EP (1) | EP0697412B1 (es) |
| JP (1) | JPH0881463A (es) |
| KR (1) | KR960007585A (es) |
| CN (1) | CN1122803A (es) |
| AT (1) | ATE188698T1 (es) |
| AU (1) | AU698939B2 (es) |
| BG (1) | BG62404B1 (es) |
| CA (1) | CA2155092A1 (es) |
| CO (1) | CO4410392A1 (es) |
| CZ (1) | CZ198895A3 (es) |
| DE (2) | DE19514313A1 (es) |
| DZ (1) | DZ1920A1 (es) |
| EE (1) | EE9500049A (es) |
| FI (1) | FI953665A (es) |
| HR (1) | HRP950428A2 (es) |
| HU (1) | HUT75037A (es) |
| IL (1) | IL114784A (es) |
| MA (1) | MA23638A1 (es) |
| NO (1) | NO305701B1 (es) |
| NZ (1) | NZ272674A (es) |
| PE (1) | PE2796A1 (es) |
| PL (1) | PL309848A1 (es) |
| RO (1) | RO115263B1 (es) |
| SK (1) | SK97495A3 (es) |
| SV (1) | SV1995000045A (es) |
| TN (1) | TNSN95088A1 (es) |
| TW (1) | TW352386B (es) |
| YU (1) | YU51095A (es) |
| ZA (1) | ZA956445B (es) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP960159A2 (en) * | 1995-04-21 | 1997-08-31 | Bayer Ag | Benzocyclopentane oxazolidinones containing heteroatoms |
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| HRP970049A2 (en) | 1996-02-06 | 1998-04-30 | Bayer Ag | New heteroaryl oxazolidinones |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| GB9609919D0 (en) * | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9717807D0 (en) * | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
| EP1049682A1 (en) | 1998-01-23 | 2000-11-08 | Versicor, Inc. | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| TR200003595T2 (tr) * | 1998-06-05 | 2001-07-23 | Astrazeneca Ab | Kimyasal bileşikler |
| GB9815880D0 (en) | 1998-07-21 | 1998-09-16 | Pfizer Ltd | Heterocycles |
| US6420349B1 (en) | 1998-08-24 | 2002-07-16 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
| WO2000029409A1 (de) * | 1998-11-17 | 2000-05-25 | Bayer Aktiengesellschaft | Neue heterocyclyl-substituierte oxazolidon-derivate |
| JP2002535680A (ja) | 1999-01-27 | 2002-10-22 | ファルマシア・アンド・アップジョン・カンパニー | 延長因子ｐ活性モジュレーターのアッセイ方法 |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| US6514529B2 (en) | 2000-03-22 | 2003-02-04 | Pharmacia & Upjohn Company | Oxazolidinone tablet formulation |
| MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US6465456B2 (en) | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
| PT1301207E (pt) | 2000-06-30 | 2005-11-30 | Pharmacia & Upjohn Co Llc | Composicoes para o tratamento de infeccoes bacterianas que contem um composto de oxazolidinona, sulbactam e ampicilina |
| HUP0303494A3 (en) * | 2000-12-15 | 2009-08-28 | Vertex Pharma | Parmaceutical compositions containing bacterial gyrase inhibitors and uses thereof |
| WO2002059116A2 (en) | 2000-12-21 | 2002-08-01 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| CA2476545A1 (en) * | 2002-03-29 | 2003-10-16 | Pharmacia & Upjohn Company | Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections |
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-
1995
- 1995-04-18 DE DE19514313A patent/DE19514313A1/de not_active Withdrawn
- 1995-06-14 TN TNTNSN95088A patent/TNSN95088A1/fr unknown
- 1995-07-18 RO RO95-01322A patent/RO115263B1/ro unknown
- 1995-07-21 EP EP95111477A patent/EP0697412B1/de not_active Expired - Lifetime
- 1995-07-21 DE DE59507595T patent/DE59507595D1/de not_active Expired - Fee Related
- 1995-07-21 AT AT95111477T patent/ATE188698T1/de active
- 1995-07-25 HR HR19514313.2A patent/HRP950428A2/hr not_active Application Discontinuation
- 1995-07-27 AU AU27230/95A patent/AU698939B2/en not_active Ceased
- 1995-07-27 US US08/508,245 patent/US5529998A/en not_active Expired - Fee Related
- 1995-07-28 JP JP7211265A patent/JPH0881463A/ja active Pending
- 1995-07-28 NZ NZ272674A patent/NZ272674A/en unknown
- 1995-07-28 SV SV1995000045A patent/SV1995000045A/es unknown
- 1995-07-31 IL IL11478495A patent/IL114784A/xx active IP Right Grant
- 1995-07-31 CA CA002155092A patent/CA2155092A1/en not_active Abandoned
- 1995-08-01 BG BG99833A patent/BG62404B1/bg unknown
- 1995-08-01 PL PL95309848A patent/PL309848A1/xx unknown
- 1995-08-01 FI FI953665A patent/FI953665A/fi unknown
- 1995-08-02 DZ DZ950098A patent/DZ1920A1/fr active
- 1995-08-02 NO NO953045A patent/NO305701B1/no unknown
- 1995-08-02 PE PE1995275165A patent/PE2796A1/es not_active Application Discontinuation
- 1995-08-02 ZA ZA956445A patent/ZA956445B/xx unknown
- 1995-08-02 HU HU9502295A patent/HUT75037A/hu unknown
- 1995-08-02 KR KR1019950023799A patent/KR960007585A/ko not_active Application Discontinuation
- 1995-08-02 SK SK974-95A patent/SK97495A3/sk unknown
- 1995-08-02 CZ CZ951988A patent/CZ198895A3/cs unknown
- 1995-08-02 EE EE9500049A patent/EE9500049A/xx unknown
- 1995-08-03 CN CN95115330A patent/CN1122803A/zh active Pending
- 1995-08-03 TW TW084108069A patent/TW352386B/zh active
- 1995-08-03 MA MA23979A patent/MA23638A1/fr unknown
- 1995-08-03 CO CO95034777A patent/CO4410392A1/es unknown
- 1995-08-11 YU YU51095A patent/YU51095A/sh unknown
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