DK0737678T3 - 4-Indolylpiperazinyl-derivater - Google Patents
4-Indolylpiperazinyl-derivaterInfo
- Publication number
- DK0737678T3 DK0737678T3 DK96302420T DK96302420T DK0737678T3 DK 0737678 T3 DK0737678 T3 DK 0737678T3 DK 96302420 T DK96302420 T DK 96302420T DK 96302420 T DK96302420 T DK 96302420T DK 0737678 T3 DK0737678 T3 DK 0737678T3
- Authority
- DK
- Denmark
- Prior art keywords
- indolylpiperazinyl
- derivatives
- alkyl
- indolylpiperazine
- substd
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/419,342 US5486518A (en) | 1995-04-10 | 1995-04-10 | 4-indolylpiperazinyl derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0737678T3 true DK0737678T3 (da) | 2002-10-07 |
Family
ID=23661842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96302420T DK0737678T3 (da) | 1995-04-10 | 1996-04-04 | 4-Indolylpiperazinyl-derivater |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5486518A (da) |
| EP (1) | EP0737678B1 (da) |
| JP (1) | JPH08319274A (da) |
| AT (1) | ATE219484T1 (da) |
| CA (1) | CA2173690A1 (da) |
| DE (1) | DE69621877T2 (da) |
| DK (1) | DK0737678T3 (da) |
| ES (1) | ES2177727T3 (da) |
| HK (1) | HK1010102A1 (da) |
| HU (1) | HUP9600914A2 (da) |
| PT (1) | PT737678E (da) |
| SI (1) | SI0737678T1 (da) |
| TW (1) | TW454005B (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0900792B1 (en) * | 1997-09-02 | 2003-10-29 | Duphar International Research B.V | Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists |
| DE69819266T2 (de) | 1997-09-02 | 2004-07-29 | Duphar International Research B.V. | Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten |
| US6376494B1 (en) * | 1998-06-15 | 2002-04-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| CA2334254A1 (en) * | 1998-06-15 | 1999-12-23 | American Home Products Corporation | Cycloalkyl-substituted aryl-piperazines, piperidines and tetrahydropyridines as serotonergic agents |
| US6306859B1 (en) | 1999-03-02 | 2001-10-23 | American Home Products Corporation | N-substituted imide derivatives with serotonergic activity |
| JP2002538154A (ja) * | 1999-03-02 | 2002-11-12 | ワイス | セロトニン作動活性を有するｎ−置換イミド誘導体 |
| US6831084B1 (en) | 1999-11-12 | 2004-12-14 | Wyeth | Branched adamantyl and noradamantyl aryl- and aralkylpiperazines with serotonin 5-HT1A activity |
| JP2003517468A (ja) | 1999-11-12 | 2003-05-27 | ワイス | セロトニン５−ｈｔ１ａ活性を有する分枝アダマンチルおよびノルアダマチルアリール−およびアラルキルピペラジン |
| US6696450B2 (en) | 2001-04-04 | 2004-02-24 | Wyeth | Serotonergic agents with long-acting in vivo effects |
| US7067518B2 (en) * | 2002-09-05 | 2006-06-27 | Wyeth | Pyridinyl-methyl-ethyl cyclohexanecarboxamides as serotonergic agents |
| US7179813B2 (en) | 2003-06-11 | 2007-02-20 | Wyeth | Bicyclic indolyl derivatives and methods for their use as serotonergic agents |
| AR078340A1 (es) | 2009-09-07 | 2011-11-02 | Vifor Int Ag | Antagonistas de la etanodiamina-hepcidina |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641029A (en) * | 1970-02-02 | 1972-02-08 | American Cyanamid Co | Substituted benzoxazolecarboxamides and benzothiazolecarboxamides |
| US3646048A (en) * | 1970-02-02 | 1972-02-29 | American Cyanamid Co | N-(tert-aminoalkyl)-2-indenecarboxamides |
| IL90279A (en) * | 1988-05-24 | 1995-03-30 | American Home Prod | History of piperazinyl carboxamide, their preparation and the pharmaceutical preparations containing them |
| DK611489A (da) * | 1988-12-08 | 1990-06-09 | Duphar Int Res | Anxiolytisk aktive piperazinderivater og farmaceutiske praeparater med indhold af saadanne forbindelser |
| GB8909209D0 (en) * | 1989-04-22 | 1989-06-07 | Wyeth John & Brother Ltd | Piperazine derivatives |
| US5340812A (en) * | 1989-04-22 | 1994-08-23 | John Wyeth & Brother, Limited | Piperazine derivatives |
| ES2130116T3 (es) * | 1989-04-22 | 1999-07-01 | Wyeth John & Brother Ltd | Derivados de piperazina. |
| GB9411099D0 (en) * | 1994-06-03 | 1994-07-27 | Wyeth John & Brother Ltd | Piperazine derivatives |
-
1995
- 1995-04-10 US US08/419,342 patent/US5486518A/en not_active Expired - Lifetime
- 1995-12-09 TW TW084113142A patent/TW454005B/zh not_active IP Right Cessation
-
1996
- 1996-03-29 JP JP8076390A patent/JPH08319274A/ja not_active Withdrawn
- 1996-04-04 ES ES96302420T patent/ES2177727T3/es not_active Expired - Lifetime
- 1996-04-04 DE DE69621877T patent/DE69621877T2/de not_active Expired - Fee Related
- 1996-04-04 SI SI9630483T patent/SI0737678T1/xx unknown
- 1996-04-04 PT PT96302420T patent/PT737678E/pt unknown
- 1996-04-04 EP EP96302420A patent/EP0737678B1/en not_active Expired - Lifetime
- 1996-04-04 AT AT96302420T patent/ATE219484T1/de not_active IP Right Cessation
- 1996-04-04 DK DK96302420T patent/DK0737678T3/da active
- 1996-04-09 HU HU9600914A patent/HUP9600914A2/hu unknown
- 1996-04-09 CA CA002173690A patent/CA2173690A1/en not_active Abandoned
-
1998
- 1998-09-24 HK HK98110927A patent/HK1010102A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69621877D1 (de) | 2002-07-25 |
| TW454005B (en) | 2001-09-11 |
| PT737678E (pt) | 2002-11-29 |
| EP0737678B1 (en) | 2002-06-19 |
| ES2177727T3 (es) | 2002-12-16 |
| US5486518A (en) | 1996-01-23 |
| HUP9600914A2 (hu) | 1998-09-28 |
| JPH08319274A (ja) | 1996-12-03 |
| HU9600914D0 (en) | 1996-05-28 |
| EP0737678A1 (en) | 1996-10-16 |
| HK1010102A1 (en) | 1999-06-11 |
| DE69621877T2 (de) | 2002-12-19 |
| SI0737678T1 (en) | 2002-10-31 |
| ATE219484T1 (de) | 2002-07-15 |
| CA2173690A1 (en) | 1996-10-11 |
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