CN86108096A - 新颖的稳定苯并咪唑衍生物 - Google Patents

新颖的稳定苯并咪唑衍生物 Download PDF

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Publication number
CN86108096A
CN86108096A CN198686108096A CN86108096A CN86108096A CN 86108096 A CN86108096 A CN 86108096A CN 198686108096 A CN198686108096 A CN 198686108096A CN 86108096 A CN86108096 A CN 86108096A CN 86108096 A CN86108096 A CN 86108096A
Authority
CN
China
Prior art keywords
amorphous
compound
acid
low alkyl
molecular formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN198686108096A
Other languages
English (en)
Chinese (zh)
Inventor
理查德·阿伦·鲁凯尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Usa Inc (us) 3401 Hillriew Avenue Palo Alto California 94303 USA
Original Assignee
Syntex Usa Inc (us) 3401 Hillriew Avenue Palo Alto California 94303 USA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Usa Inc (us) 3401 Hillriew Avenue Palo Alto California 94303 USA filed Critical Syntex Usa Inc (us) 3401 Hillriew Avenue Palo Alto California 94303 USA
Publication of CN86108096A publication Critical patent/CN86108096A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C07D235/32—Benzimidazole-2-carbamic acids, unsubstituted or substituted; Esters thereof; Thio-analogues thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN198686108096A 1985-11-27 1986-11-27 新颖的稳定苯并咪唑衍生物 Pending CN86108096A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80250885A 1985-11-27 1985-11-27
US802,508 1985-11-27

Publications (1)

Publication Number Publication Date
CN86108096A true CN86108096A (zh) 1987-07-08

Family

ID=25183897

Family Applications (1)

Application Number Title Priority Date Filing Date
CN198686108096A Pending CN86108096A (zh) 1985-11-27 1986-11-27 新颖的稳定苯并咪唑衍生物

Country Status (14)

Country Link
EP (1) EP0224257A1 (enExample)
JP (1) JPS62155264A (enExample)
CN (1) CN86108096A (enExample)
AU (1) AU6569986A (enExample)
BR (1) BR8605798A (enExample)
DD (1) DD252540A5 (enExample)
DK (1) DK569686A (enExample)
FI (1) FI864813A7 (enExample)
HU (1) HU198025B (enExample)
IL (1) IL80768A0 (enExample)
IN (1) IN164294B (enExample)
NO (1) NO864740D0 (enExample)
PT (1) PT83811B (enExample)
ZA (1) ZA868962B (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102452987A (zh) * 2010-10-28 2012-05-16 桂林南药股份有限公司 一种不定形晶型阿苯达唑的制备方法
CA2987867C (en) 2015-06-09 2023-06-27 Capsugel Belgium Nv Formulations to achieve rapid dissolution of drug from spray-dried dispersions in capsules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS601101A (ja) * 1983-06-15 1985-01-07 Yuukou Yakuhin Kogyo Kk 水性懸濁農薬製剤
DE3347579A1 (de) * 1983-12-30 1985-07-11 Hoechst Ag, 6230 Frankfurt Zubereitungen schwer wasserloeslicher anthelminthika und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK569686A (da) 1987-05-28
AU6569986A (en) 1987-06-04
FI864813A0 (fi) 1986-11-26
PT83811B (en) 1988-03-15
PT83811A (en) 1986-12-01
HU198025B (en) 1989-07-28
IN164294B (enExample) 1989-02-11
IL80768A0 (en) 1987-02-27
EP0224257A1 (en) 1987-06-03
HUT42076A (en) 1987-06-29
FI864813A7 (fi) 1987-05-28
BR8605798A (pt) 1987-08-25
NO864740D0 (no) 1986-11-26
JPS62155264A (ja) 1987-07-10
DD252540A5 (de) 1987-12-23
ZA868962B (en) 1988-07-27
DK569686D0 (da) 1986-11-26

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