CN1882354B - 细胞因子调节剂及相关用法 - Google Patents

细胞因子调节剂及相关用法 Download PDF

Info

Publication number
CN1882354B
CN1882354B CN200480026054XA CN200480026054A CN1882354B CN 1882354 B CN1882354 B CN 1882354B CN 200480026054X A CN200480026054X A CN 200480026054XA CN 200480026054 A CN200480026054 A CN 200480026054A CN 1882354 B CN1882354 B CN 1882354B
Authority
CN
China
Prior art keywords
composition
extract
bilberry
inflammatory
blackberry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CN200480026054XA
Other languages
English (en)
Chinese (zh)
Other versions
CN1882354A (zh
Inventor
R·K·伦道夫
H·罗哈-舒密特
M·A·默里
A·W·卡罗福特
K·W·格伦贝克
D·J·普萨特里
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Access Business Group International LLC
Original Assignee
Access Business Group International LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Access Business Group International LLC filed Critical Access Business Group International LLC
Publication of CN1882354A publication Critical patent/CN1882354A/zh
Application granted granted Critical
Publication of CN1882354B publication Critical patent/CN1882354B/zh
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738—Rosa (rose)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/82—Theaceae (Tea family), e.g. camellia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
CN200480026054XA 2003-09-12 2004-09-10 细胞因子调节剂及相关用法 Expired - Lifetime CN1882354B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50275503P 2003-09-12 2003-09-12
US60/502,755 2003-09-12
PCT/IB2004/051742 WO2005025586A1 (en) 2003-09-12 2004-09-10 Cytokine modulators and related method of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2011102725632A Division CN102309573B (zh) 2003-09-12 2004-09-10 细胞因子调节剂及相关用法

Publications (2)

Publication Number Publication Date
CN1882354A CN1882354A (zh) 2006-12-20
CN1882354B true CN1882354B (zh) 2012-07-04

Family

ID=34312420

Family Applications (2)

Application Number Title Priority Date Filing Date
CN200480026054XA Expired - Lifetime CN1882354B (zh) 2003-09-12 2004-09-10 细胞因子调节剂及相关用法
CN2011102725632A Expired - Lifetime CN102309573B (zh) 2003-09-12 2004-09-10 细胞因子调节剂及相关用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN2011102725632A Expired - Lifetime CN102309573B (zh) 2003-09-12 2004-09-10 细胞因子调节剂及相关用法

Country Status (6)

Country Link
US (1) US7838050B2 (enExample)
JP (1) JP4903569B2 (enExample)
KR (1) KR101245440B1 (enExample)
CN (2) CN1882354B (enExample)
TW (2) TWI358300B (enExample)
WO (1) WO2005025586A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005025586A1 (en) 2003-09-12 2005-03-24 Access Business Group International Llc Cytokine modulators and related method of use
US7758902B2 (en) 2003-09-12 2010-07-20 Access Business Group International Llc Cytokine modulators and related methods of use
US7758903B2 (en) 2003-09-12 2010-07-20 Access Business Group International Llc Cytokine modulators and related methods of use
US20050260290A1 (en) * 2004-05-20 2005-11-24 Rutgers, The State University Of New Jersey Botanical anti-inflammatory compositions and methods
JP4703280B2 (ja) * 2005-06-15 2011-06-15 ポーラ化成工業株式会社 オイル化粧料
CN101291681A (zh) * 2005-08-23 2008-10-22 捷通国际有限公司 细胞因子调节物及相关使用方法
US20070154581A1 (en) * 2005-12-30 2007-07-05 Kumar Kalyani M Composition and method for enhancing or stimulating the immune system
EP2034855A2 (en) * 2006-05-12 2009-03-18 Interleukin Genetics, Inc. Food compositions and methods of treating periodontal disease
JP5170577B2 (ja) * 2006-07-14 2013-03-27 ディーエスエム アイピー アセッツ ビー．ブイ． 炎症障害の治療のためにバラの実および他の活性剤を含んでなる組成物
KR101471215B1 (ko) 2006-10-24 2014-12-09 크렘핀, 로리에 항-재흡수 및 골 형성 식이보충제 및 이의 사용 방법
EP1925301A1 (en) * 2006-11-24 2008-05-28 DSMIP Assets B.V. Use of tricyclic diterpenes and their derivatives for the treatment, co-treatment or prevention of inflammatory disorders and/or joint disorders
US7875300B2 (en) * 2006-11-24 2011-01-25 Rutgers, The State University Of New Jersey Methods for reducing circulating glucose levels
JP5372358B2 (ja) * 2007-01-20 2013-12-18 美智士 谷 生体活性治療物質
US20080254110A1 (en) * 2007-04-10 2008-10-16 Marvin Heuer Composition For Enhancing Immunity and Reducing Inflammation Related to Infections
WO2009132463A1 (en) * 2008-05-02 2009-11-05 Neptune Technologies & Bioressources Inc. New deodorization method and organoleptic improvement of marine oil extracts
JP2010013403A (ja) * 2008-07-04 2010-01-21 Kao Corp Ｎｆａｔシグナル阻害剤及びｎｆａｔシグナル阻害方法
KR101326162B1 (ko) * 2009-10-01 2013-11-07 재단법인 제주테크노파크 항염증성 조성물
JP5827625B2 (ja) 2009-10-29 2015-12-02 アカスティ ファーマ インコーポレイテッド 濃縮治療用リン脂質組成物
US8609157B2 (en) 2009-10-30 2013-12-17 Tharos Ltd. Solvent-free process for obtaining phospholipids and neutral enriched krill oils
CN104066434A (zh) * 2012-01-30 2014-09-24 捷通国际有限公司 抗炎和抗氧化组合物和相关使用方法
JP6533639B2 (ja) * 2012-03-16 2019-06-19 株式会社コーセー 皮膚外用剤及び紫外線によるカロテノイド含有油性成分の分解抑制方法
ITMI20121570A1 (it) * 2012-09-20 2014-03-21 Indena Spa Nuovi estratti di cynara scolimus, coffea spp. e olea europaea per il trattamento della sindrome metabolica
US9023399B2 (en) * 2012-11-16 2015-05-05 NU Technology, LLC Water-soluble anti-inflammatory cream with natural ingredients base
US8962041B2 (en) * 2013-02-12 2015-02-24 Johnson & Johnson Consumer Companies, Inc. Methods and compositions for enhancing hair quality using blackberry extract
CN106413732A (zh) 2014-03-14 2017-02-15 新篇章股份有限公司 补充食品
EP3236979A4 (en) * 2014-12-19 2018-08-15 Paradise Health, Inc. Methods for reducing platelet aggregation and treating cardiovascular disease and other medical disorders
US9622498B2 (en) 2015-07-17 2017-04-18 Vera Roasting Company, Inc. Roasted coffee with resveratrol
US20170035789A1 (en) * 2015-08-05 2017-02-09 Bill H. McAnalley Composition Of Dietary Supplements Based On Apoptosis that Support Optimal Health
FR3042413B1 (fr) * 2015-10-20 2019-07-12 Valbiotis Composition comprenant un melange de molecules extraites de chrysanthellum indicum et de cynara scolymus et utilisation pour agir sur le metabolisme glucidique et/ou lipidique
KR101990000B1 (ko) 2018-03-02 2019-09-30 강원대학교산학협력단 초석잠 뿌리 추출물 또는 이의 분획물을 유효성분으로 포함하는 기능성 조성물
JP7499015B2 (ja) * 2019-10-10 2024-06-13 小林製薬株式会社 神経変性疾患の予防剤及び／又は治療剤
CN114550949A (zh) * 2022-02-28 2022-05-27 首都医科大学附属北京儿童医院 一种儿童药物适口性评价系统

Family Cites Families (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US74147A (en) * 1868-02-04 Thomas bosbkugh
US638542A (en) * 1899-06-07 1899-12-05 William w wood Portable boat-motor.
US4110483A (en) * 1977-08-01 1978-08-29 The United States Of America As Represented By The Secretary Of The Army Method of stabilizing foods with an antioxidant
JPH062677B2 (ja) * 1984-05-26 1994-01-12 日産化学工業株式会社 造血臓器回復促進剤
SU1697820A1 (ru) * 1985-09-10 1991-12-15 1-Й Московский Медицинский Институт Им.И.М.Сеченова Средство дл лечени сахарного диабета
DE3784522T2 (de) * 1987-12-23 1993-06-17 Psoricur Ltd Medizinische zusammensetzungen gegen psoriasis.
US5540931A (en) * 1989-03-03 1996-07-30 Charles W. Hewitt Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
DE4202657C2 (de) * 1992-01-31 1995-10-12 Schaper & Bruemmer Gmbh Pharmazeutisch wirksame Zusammensetzung aus Tanacetum parthenium sowie Verfahren zu deren Extraktion und mit der pharmazeutisch wirksamen Zusammensetzung hergestelltes Arzneimittel
HU213479B (en) 1992-10-08 1997-10-28 Burian Process for producing natural pharmaceutical compositions for preventing and treating diseases of parodontium and gingiva
HU210952B (en) 1992-11-24 1995-09-28 Lenart Process for making a composition containing extract of herbs, and cosmetics containing the composition
JPH0799924A (ja) 1993-09-30 1995-04-18 Nippon Suisan Kaisha Ltd アスタキサンチンを主要成分とするファフィア色素油の安定な粉末化物及びその製造方法
CN1102993A (zh) * 1993-12-21 1995-05-31 吴文才 多酶体系加工中草药的制剂方法
JPH07300421A (ja) 1994-04-28 1995-11-14 Itano Reitou Kk 抗炎症剤
RU2053265C1 (ru) * 1994-09-17 1996-01-27 Лоенко Юрий Николаевич Композиция ингредиентов для бальзама "гомеопат"
US5527533A (en) * 1994-10-27 1996-06-18 Board Of Trustees Of The University Of Illinois Method of retarding and ameliorating central nervous system and eye damage
UA51613C2 (uk) * 1995-03-06 2002-12-16 Еміль Флахсман Аг Спосіб вилучення небажаних ліпофільних домішок та/або залишків, що містяться в напоях або рослинних препаратах
US5916565A (en) * 1996-03-08 1999-06-29 In Clover, Inc. Product and method for treating joint disorders in vertebrates
US6391310B1 (en) * 1996-03-13 2002-05-21 Archer Daniels Midland Company Method of preparing and using isoflavones for the treatment of neurological symptoms
US5854291A (en) * 1996-04-23 1998-12-29 Medical Merchandising, Inc. Pain reliever and method of use
US5683698A (en) * 1996-08-02 1997-11-04 New England Deaconess Hospital Formulation for alleviating symptoms associated with arthritis
DK0915693T3 (da) * 1996-08-02 2004-02-09 Plum Kemi Produktion As En olie-i-vand emulsion til brug på menneskers hud for at rengøre, beskytte eller forbedre hudens tilstand
US6642277B1 (en) * 1996-09-20 2003-11-04 The Howard Foundation Food supplements containing polyphenols
US6512848B2 (en) * 1996-11-18 2003-01-28 Canon Kabushiki Kaisha Page analysis system
US5714150A (en) * 1997-01-08 1998-02-03 Nachman; Leslie Method for producing extract of olive leaves
SE522246C2 (sv) 1997-02-27 2004-01-27 Astacarotene Ab Oralt preparat för profylaktisk och terapeutisk behandling av Helicobacter Sp. infektion
US6238675B1 (en) * 1997-02-27 2001-05-29 Campamed Corp. Method of preparation and composition of a water soluble extract of the plant species Uncaria for enhancing immune, anti-inflammatory and anti-tumor processes of warm blooded animals
WO1998045241A2 (en) 1997-04-04 1998-10-15 Henkel Corporation Lutein esters having high bioavailability
KR100423885B1 (ko) * 1997-04-18 2004-09-01 씨제이 주식회사 블루베리 과즙과 알파파 증진 음료용 조성물을함유하는 음료
US6103218A (en) * 1997-04-23 2000-08-15 Brucker; Donald Therapeutic nasal spray administered composition containing feverfew
FR2766176B1 (fr) * 1997-07-15 1999-10-29 Caudalie Compositions a base de derives de resveratrol
US20030161897A1 (en) * 1997-09-16 2003-08-28 Edward Shanbrom Soluble plant derived natural color concentrates and antimicrobial nutraceuticals
FR2768622B1 (fr) * 1997-09-22 1999-11-26 Oreal Extrait de rosacees en tant qu'antagoniste de bradykinine
FR2768621B1 (fr) * 1997-09-22 2000-04-07 Oreal Utilisation d'un extrait d'au moins un vegetal de la famille des rosacees
US6414037B1 (en) * 1998-01-09 2002-07-02 Pharmascience Pharmaceutical formulations of resveratrol and methods of use thereof
AT407821B (de) * 1998-03-24 2001-06-25 Franz Dr Stueckler Mittel auf der basis von naturstoffen
KR100264773B1 (ko) * 1998-04-02 2000-09-01 윤종용 자기 정렬된 콘택홀을 갖는 반도체 장치의제조 방법
AUPP291598A0 (en) * 1998-04-14 1998-05-07 Allrad 3 Pty Ltd Food supplement
US6024960A (en) * 1998-04-17 2000-02-15 Otto Torbjorn Hansen And Marianne Hansen Rose-hip formulations as anti-inflammatory natural medicine for alleviating/reducing symptoms associated with inflammation and arthritis
HRP990080B1 (en) * 1999-03-12 2003-04-30 Vladimir Leko Plant mixture and a medical preparation for the treatment of diabetes mellitus, type ii, obtained therefrom
US6231866B1 (en) * 1998-04-30 2001-05-15 Douglas G. Mann Infused vegetable, fruit, herb, and/or seed fiber product and dietary supplements containing same
US20020168429A1 (en) * 1998-04-30 2002-11-14 Mann Douglas G. Nutritional supplement and method of delivery
US6022901A (en) * 1998-05-13 2000-02-08 Pharmascience Inc. Administration of resveratrol to prevent or treat restenosis following coronary intervention
AU4084599A (en) * 1998-05-18 1999-12-06 Oklahoma Medical Research Foundation Resveratrol inhibition of myeloperoxidase
US20020182260A1 (en) * 1998-05-29 2002-12-05 Cellegy Pharmaceuticals, Inc. Anti-inflammatory agents and methods for their preparation and use
US6068999A (en) * 1998-06-25 2000-05-30 Hendrix; Curt Dietary supplement for supporting cerebrovascular tone and treating migraine headaches
US20030086986A1 (en) * 1998-08-06 2003-05-08 Bruijn Chris De Ophthalmic, pharmaceutical and other healthcare preparations with naturally occurring plant compounds, extracts and derivatives
US6656925B2 (en) * 1998-09-09 2003-12-02 Advanced Medical Instruments Composition and method of treating arthritis
US6716883B1 (en) * 1998-12-24 2004-04-06 1333366 Ontario Inc. Composition useful to treat periodontal disease
FR2790645B1 (fr) * 1999-03-12 2001-06-08 Arkopharma Laboratoires Complement alimentaire et procede de traitement cosmetique a base d' un extrait de raisin riche en polyphenols
EP1100516B1 (en) * 1999-06-03 2005-03-23 Johnson & Johnson Consumer France SAS Extracts of feverfew (tanacetum parthenium) against inflammatory disorders
IT1312342B1 (it) * 1999-06-03 2002-04-15 Indena Spa Estratto di tanacetum parthenium sostanzialmente privo di gammalattoni-alfa-insaturi.
PT1202743E (pt) * 1999-06-18 2005-02-28 Jon Bragi Bjarnason Composicoes farmaceuticas e cosmeticas compreendendo serina-proteases de bacalhau e sua utilizacao farmaceutica e cosmetica
US6274176B1 (en) * 1999-07-01 2001-08-14 Chromak Research, Inc. Herbal compositions and their use as anti-inflammatory agents for alleviation of arthritis and gout
KR100814297B1 (ko) * 1999-07-09 2008-03-18 썬 팜 코포레이션 악성 종양 및 바이러스 감염을 치료하고 면역 기능을 향상시키기 위한 식이 보충제
KR20060123663A (ko) * 1999-08-27 2006-12-01 미시간 스테이트 유니버시티 천연 사이클로옥시게나제 저해물질을 함유하는 조성물
US6264995B1 (en) * 1999-10-19 2001-07-24 Thomas Newmark Herbal composition for reducing inflammation and methods of using same
US6358542B2 (en) * 1999-12-20 2002-03-19 Usana, Inc. Antioxidant compositions extracted from olives and olive by-products
ES2157178B1 (es) * 1999-12-23 2002-02-16 Asac Compania De Biotecnologia Procedimiento de obtencion de extractos de olea europaea y aplicaciones de los mismos.
US6238696B1 (en) * 2000-01-07 2001-05-29 Gaia Herbs, Inc. Process for providing herbal medicants in cellulose derivative capsules
US6759062B2 (en) * 2000-02-23 2004-07-06 Bioselect Innovations, Inc. Composition and method for treating the effects of diseases and maladies
US20010039296A1 (en) * 2000-03-23 2001-11-08 Debasis Bagchi Method and composition for preventing or reducing the symptoms of menopause
IT1318425B1 (it) * 2000-03-24 2003-08-25 D B P Dev Biotechnological Pro Impiego del resveratrolo per il trattamento di eczema desquamativo,acne e psoriasi.
US7078040B2 (en) * 2000-03-27 2006-07-18 Fuji Chemical Industry Co., Ltd. Method of inhibiting the expression of inflammatory cytokines and chemokines
US20020054924A1 (en) * 2000-04-13 2002-05-09 Leahy Margaret M. Novel compositions derived from cranberry and grapefruit and therapeutic uses therefor
FR2808190B1 (fr) * 2000-04-28 2002-06-21 Oreal Extrait de vegetal de l'espece vitis vinifera comme inhibiteur de no-synthase et utilisations
US6391345B1 (en) * 2000-05-12 2002-05-21 Tim Heeg Cranberry seed oil, cranberry seed flour and a method for making
CA2412435A1 (en) * 2000-06-13 2001-12-20 Edward A. Lemmo Phytonutrient formula for the relief of chronic pain resulting from inflammation
US6492429B1 (en) * 2000-07-10 2002-12-10 N.V. Nutricia Composition for the treatment of osteoarthritis
US6333056B1 (en) * 2000-08-14 2001-12-25 Ralph Stanley Robinson Herbal-based pharmaceutical formulations
EP1328282B1 (en) * 2000-08-31 2006-05-31 Phenolics, LLC Efficient method for producing compositions enriched in anthocyanins
US6468541B2 (en) * 2000-08-31 2002-10-22 Chinese Herbal Usa, Inc. Natural, non-allergenic, immune system stimulant
US6485752B1 (en) * 2000-10-23 2002-11-26 Otto Torbjorn Hansen Composition and method for alleviating joint pain and stiffness
DE10153949A1 (de) 2000-11-07 2002-08-01 Engelbert Grzeschik Verwendung von Beerensamenölen
WO2002039956A2 (en) * 2000-11-15 2002-05-23 Rutgers, The State University Of New Jersey Black tea extract for prevention of disease
US20020119173A1 (en) * 2000-12-22 2002-08-29 Lin Samuel Qcheng Cosmetic compositions for preventing skin irritation
US20030190381A1 (en) * 2001-02-02 2003-10-09 Bland Jeffrey S. Medical composition for balancing bodily processes
US20030077343A1 (en) * 2001-03-16 2003-04-24 Martin Katharine M. Composition containing feverfew extract and use thereof
US6582736B2 (en) * 2001-03-23 2003-06-24 Terra De Sol Therapeutic oil composition
KR100439209B1 (ko) * 2001-03-30 2004-07-07 남종현 스테미너 증진용 천연차 및 그 제조방법
US6387416B1 (en) * 2001-04-05 2002-05-14 Thomas Newmark Anti-Inflammatory herbal composition and method of use
US20020182270A1 (en) * 2001-05-31 2002-12-05 Stier Roger E. Edible compositions comprising freeze-dried flavoring agents
US20040037903A1 (en) * 2001-06-13 2004-02-26 Lemmo Edward A. Phytonutrient formula for the relief of chronic pain resulting from inflammation
US20030044474A1 (en) * 2001-08-03 2003-03-06 Shaklee Corporation High molecular weight, lipophilic, orally ingestible bioactive agents in formulations having improved bioavailability
CA2456743A1 (en) * 2001-08-21 2003-02-27 Galileo Pharmaceuticals, Inc. Tocopherol enriched compositions and amelioration of inflammatory symptoms
US6638542B2 (en) * 2001-09-20 2003-10-28 Nutricia N.V. Reducing appetite in mammals by administering procyanidin and hydroxycitric acid
US20030108627A1 (en) * 2001-09-25 2003-06-12 Jonathan Selzer Cranberry based dietary supplement and dental hygiene product
US6986906B2 (en) * 2001-09-25 2006-01-17 Herbasway Laboratories, Llc Cranberry based dietary supplement and dental hygiene product
US6464982B1 (en) * 2001-11-02 2002-10-15 Chinese Herbal Usa, Inc. Herbal immune system stimulant
DK1453844T3 (da) * 2001-11-21 2014-02-10 Univ Aarhus Anvendelse af glycosider af mono- og diacylglycerol som anti-inflammatoriske midler
US6713096B2 (en) * 2002-01-04 2004-03-30 Melaleuca, Inc. Dietary supplements and methods for treating pain and inflammation
JP4477354B2 (ja) * 2002-01-10 2010-06-09 ルピン・リミテッド 乾癬を含む様々な疾患を処置するための薬草組成物、その調製方法およびそのような疾患を処置するための方法
CA2473698A1 (en) 2002-01-16 2003-07-31 Natural Alternatives International, Inc. Anti-inflammatory formulations
US6579543B1 (en) * 2002-02-22 2003-06-17 Jackie H. McClung Composition for topical application to skin
WO2003103583A2 (en) * 2002-06-10 2003-12-18 Oklahoma Medical Research Foundation A method for using tethered bis(polyhydroxyphenyls) and o-alkyl derivatives thereof in treating inflammatory conditions of the central nervous system
US7138129B2 (en) * 2002-07-31 2006-11-21 Melaleuca, Inc. Skin care compositions
US20040109905A1 (en) * 2002-09-18 2004-06-10 Debasis Bagchi Method and composition of anthocyanin-rich berry extracts that prevents or inhibits angiogenesis and helicobacter pylori and acts as a powerful antioxidant that provides various health benefits
US20040086579A1 (en) * 2002-11-05 2004-05-06 Higgins James W. Dietary supplement comprising parthenolide
CA2507704A1 (en) * 2002-12-02 2004-06-17 Mars, Incorporated Flavanols and procyanidins promote homeostasis
US6887497B2 (en) * 2002-12-19 2005-05-03 Vitacost.Com, Inc. Composition for the treatment and prevention of osteoarthritis, rheumatoid arthritis and improved joint function
US20040151761A1 (en) * 2003-02-05 2004-08-05 The Procter & Gamble Company Methods and compositions utilizing astaxanthin
US20040247706A1 (en) * 2003-06-06 2004-12-09 Roberts Stephen C. Transdermal dietary supplement comprising parthenolide
AU2004273813A1 (en) 2003-09-12 2005-03-31 Access Business Group International Llc Program for regulating health conditions
WO2005025586A1 (en) 2003-09-12 2005-03-24 Access Business Group International Llc Cytokine modulators and related method of use
US20050260290A1 (en) 2004-05-20 2005-11-24 Rutgers, The State University Of New Jersey Botanical anti-inflammatory compositions and methods

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
J.WANG,and MAZZA.INHIBITORY EFFECTS OF ANTHOCYANINS AND OTHERPHENOLIC COMPOUNDS ON NITRIC OXIDEPRODUCTION IN LPS/IFN-GAMMA-ACTIVATED RAW264.7 MACROPHAGES.AGRICULTURAL AND FOOD CHEMISTRY4 50.2002,4(50),850-857.
J.WANG,and MAZZA.INHIBITORY EFFECTS OF ANTHOCYANINS AND OTHERPHENOLIC COMPOUNDS ON NITRIC OXIDEPRODUCTION IN LPS/IFN-GAMMA-ACTIVATED RAW264.7 MACROPHAGES.AGRICULTURAL AND FOOD CHEMISTRY4 50.2002,4(50),850-857. *
Martin Guerin 等.Haematococcus astaxanthin: applications for human healthand nutrition.TRENDS IN BIOTECHNOLOGY21 5.2003,21(5),210-215.
Martin Guerin 等.Haematococcus astaxanthin: applications for human healthand nutrition.TRENDS IN BIOTECHNOLOGY21 5.2003,21(5),210-215. *
冯永红等.白藜芦醇药理作用研究进展.国外医药·植物药分册 4.1996,(4),摘要.
冯永红等.白藜芦醇药理作用研究进展.国外医药·植物药分册 4.1996,(4),摘要. *

Also Published As

Publication number Publication date
CN1882354A (zh) 2006-12-20
CN102309573A (zh) 2012-01-11
US7838050B2 (en) 2010-11-23
JP4903569B2 (ja) 2012-03-28
TWI358300B (en) 2012-02-21
CN102309573B (zh) 2013-11-20
WO2005025586B1 (en) 2005-05-06
US20050058728A1 (en) 2005-03-17
WO2005025586A1 (en) 2005-03-24
TW201206455A (en) 2012-02-16
KR101245440B1 (ko) 2013-03-19
JP2007513868A (ja) 2007-05-31
KR20070028276A (ko) 2007-03-12
TW200518765A (en) 2005-06-16

Similar Documents

Publication Publication Date Title
CN1882354B (zh) 细胞因子调节剂及相关用法
JP2007513868A5 (enExample)
Calvano et al. Dietary berries, insulin resistance and type 2 diabetes: An overview of human feeding trials
Seal Whole grains and CVD risk
JP4741801B2 (ja) 花粉症、アレルギー性鼻炎、アトピー性皮膚炎、喘息又は蕁麻疹の予防又は治療用組成物
KR101682489B1 (ko) 대사성 증후군의 조절을 위한 스파란터스 인디커스 및 가르시니아 망고스타나 유래의 조성물
Xu et al. Sulforaphane ameliorates glucose intolerance in obese mice via the upregulation of the insulin signaling pathway
JP2019534331A (ja) 腸の健康を促す組成物
US20140148399A1 (en) Compositions and methods for treating or ameliorating obesity or for reducing diabetic hypercholesterolemia
US7758902B2 (en) Cytokine modulators and related methods of use
US7758903B2 (en) Cytokine modulators and related methods of use
KR20080041703A (ko) 사이토킨 조절인자 및 관련된 이용 방법
US20180343906A1 (en) Composition comprising cinnamon extract
CN104363918A (zh) 斐济果果实提取物
KR20070108291A (ko) 알레르기 증상의 예방 또는 개선 작용을 갖는 음식물 및당해 음식물의 제조방법
Ueda et al. Chrysanthemum flower oil inhibits diet-induced serum uric acid elevation in adult male subjects: A randomised, double-blind, placebo-controlled cross-over comparison study
RU2228190C1 (ru) Композиция с иммуностимулирующими свойствами
HK1125563A (en) Cytokine modulators and related methods of use
HK1098366A (en) Cytokine modulators and related method of use
US12397030B2 (en) Polyphenol compositions and uses thereof
Fadimatou et al. In vitro antidiabetic potential of two formulated powders of some nutraceutical plants of Cameroon
Deshmukh et al. Disorders of the Urogenital System in Aging and Nutraceuticals
KR20050018662A (ko) 화분증, 알레르기성 비염, 아토피성 피부염, 천식 또는담마진의 예방 또는 치료 용 조성물

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1098366

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1098366

Country of ref document: HK

CX01 Expiry of patent term
CX01 Expiry of patent term

Granted publication date: 20120704