CN1774447B - 肺炎链球菌抗原 - Google Patents
肺炎链球菌抗原 Download PDFInfo
- Publication number
- CN1774447B CN1774447B CN200480010200XA CN200480010200A CN1774447B CN 1774447 B CN1774447 B CN 1774447B CN 200480010200X A CN200480010200X A CN 200480010200XA CN 200480010200 A CN200480010200 A CN 200480010200A CN 1774447 B CN1774447 B CN 1774447B
- Authority
- CN
- China
- Prior art keywords
- antibody
- streptococcus pneumoniae
- antigen
- nucleic acid
- fragment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03450087.6 | 2003-04-15 | ||
| EP03450087 | 2003-04-15 | ||
| PCT/EP2004/003984 WO2004092209A2 (en) | 2003-04-15 | 2004-04-15 | S. pneumoniae antigens |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100423445A Division CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1774447A CN1774447A (zh) | 2006-05-17 |
| CN1774447B true CN1774447B (zh) | 2011-04-06 |
Family
ID=33186037
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN200480010200XA Expired - Fee Related CN1774447B (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
| CN2011100423445A Pending CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011100423445A Pending CN102174534A (zh) | 2003-04-15 | 2004-04-15 | 肺炎链球菌抗原 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US7635487B2 (OSRAM) |
| EP (11) | EP2311987A1 (OSRAM) |
| JP (3) | JP2007525157A (OSRAM) |
| CN (2) | CN1774447B (OSRAM) |
| AU (1) | AU2004230244B2 (OSRAM) |
| CA (1) | CA2522238A1 (OSRAM) |
| WO (1) | WO2004092209A2 (OSRAM) |
Families Citing this family (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6800744B1 (en) * | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
| US7128918B1 (en) | 1998-12-23 | 2006-10-31 | Id Biomedical Corporation | Streptococcus antigens |
| US7262024B2 (en) | 2001-12-20 | 2007-08-28 | Id Biomedical Corporation | Streptococcus antigens |
| CA2545325C (en) * | 2003-11-10 | 2015-01-13 | Uab Research Foundation | Compositions for reducing bacterial carriage and cns invasion and methods of using same |
| EP2081953A2 (en) * | 2006-08-17 | 2009-07-29 | The UAB Research Foundation | Immunogenic pcpa polypeptides and uses thereof |
| WO2008039838A2 (en) | 2006-09-27 | 2008-04-03 | St. Jude Children's Research Hospital | Synthetic streptococcus pneumoniae vaccine |
| EP1923069A1 (en) * | 2006-11-20 | 2008-05-21 | Intercell AG | Peptides protective against S. pneumoniae and compositions, methods and uses relating thereto |
| BRPI0721702A2 (pt) * | 2007-05-23 | 2013-01-15 | Uab Research Foundation | neuraminidase pneumocàcica destoxificada ou uma porÇço antigÊnica da mesma, composiÇço, mÉtodos para reduzir ou prevenir a portabilidade nasal pneumocàcica em um indivÍduo, e para reduzir ou prevenir a infecÇço pneumocàcica em um indivÍduo, e, recipiente |
| BRPI0811908A2 (pt) * | 2007-05-25 | 2014-11-18 | Novartis Ag | Antígenos de pilus de streptococcus pneumoniae |
| ES2397488T3 (es) * | 2007-07-23 | 2013-03-07 | Sanofi Pasteur Limited | Polipéptidos inmunógenos y anticuerpos monoclonales |
| US20160228500A9 (en) * | 2007-07-23 | 2016-08-11 | Martina Ochs | Immunogenic Polypeptides and Monoclonal Antibodies |
| GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
| BRPI0907010A2 (pt) * | 2008-02-01 | 2015-07-07 | Sanofi Pasteur Ltd | Análise para o diagnóstico de streptococcus pneumoniae |
| KR101208778B1 (ko) | 2008-03-03 | 2012-12-05 | 노파르티스 아게 | Tlr 활성 조정제로서의 화합물 및 조성물 |
| JP2011514167A (ja) * | 2008-03-17 | 2011-05-06 | インターセル アーゲー | 肺炎連鎖球菌(S.pneumoniae)に対して保護的なペプチドならびにそれに関連する組成物、方法、および使用 |
| EP2108656A1 (en) * | 2008-03-19 | 2009-10-14 | Beninati, Concetta | Antigenic protein fragments of streptococcus pneumoniae |
| US11839430B2 (en) | 2008-03-27 | 2023-12-12 | Doheny Eye Institute | Optical coherence tomography-based ophthalmic testing methods, devices and systems |
| US8348429B2 (en) | 2008-03-27 | 2013-01-08 | Doheny Eye Institute | Optical coherence tomography device, method, and system |
| WO2010009447A2 (en) | 2008-07-18 | 2010-01-21 | Doheny Eye Institute | Optical coherence tomography - based ophthalmic testing methods, devices and systems |
| US20110171224A1 (en) * | 2008-05-22 | 2011-07-14 | Orihuela Carlos J | PsrP IS A PROTECTIVE ANTIGEN AGAINST PNEUMOCOCCAL INFECTION |
| ES2352704B1 (es) * | 2008-08-08 | 2012-06-14 | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)(Titular al 80%) | Secuencia de nucleotido y proteina b-galactosidasa de streptococcus mitis, procedimiento de obtencion y sus aplicaciones. |
| EP2327782B1 (en) * | 2008-09-04 | 2015-02-25 | Biotechnology Research Institute Chinese Academy of Agricultural Sciences | Dna molecule for expressing haripin rna, the constructing method and the use thereof |
| EP2328611A4 (en) * | 2008-09-11 | 2011-10-12 | Univ Ben Gurion | COMPOSITIONS AND METHODS FOR THE TREATMENT OF S. PNEUMONIAE INFECTION |
| ATE523204T1 (de) | 2009-02-16 | 2011-09-15 | Karlsruher Inst Technologie | Cd44v6-peptide als bakterielle infektionsinhibitoren |
| JP5668049B2 (ja) | 2009-03-24 | 2015-02-12 | ノバルティス アーゲー | 髄膜炎菌h因子結合タンパク質および肺炎球菌糖結合体の組み合わせ |
| TR201802380T4 (tr) | 2009-06-10 | 2018-03-21 | Glaxosmithkline Biologicals Sa | Benzonaftiridin içeren aşılar. |
| CN102548572A (zh) * | 2009-06-29 | 2012-07-04 | 健诺西生物科学公司 | 抗肺炎链球菌的疫苗和组合物 |
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| CN102905703B (zh) | 2010-03-23 | 2016-09-28 | 诺华股份有限公司 | 作为tlr2激动剂用于治疗感染、炎症、呼吸疾病等的化合物(基于半胱氨酸的脂肽)和组合物 |
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| CN104519910B (zh) | 2012-03-07 | 2017-05-03 | 诺华股份有限公司 | 肺炎链球菌抗原的含佐剂制剂 |
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| RU2510281C2 (ru) | 2012-06-22 | 2014-03-27 | Общество с ограниченной ответственностью "Эпитоп" (ООО "Эпитоп") | ВАКЦИНА ПРОТИВ ПНЕВМОНИИ, ВЫЗЫВАЕМОЙ Streptococcus pneumoniae, НА ОСНОВЕ ГИБРИДНОГО БЕЛКА |
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| JP6494527B2 (ja) | 2013-02-07 | 2019-04-03 | ザ チルドレンズ メディカル センター コーポレーション | 肺炎球菌のコロニー形成および/または疾患からの保護を提供するタンパク質抗原 |
| US9226856B2 (en) | 2013-03-14 | 2016-01-05 | Envision Diagnostics, Inc. | Inflatable medical interfaces and other medical devices, systems, and methods |
| US10772497B2 (en) | 2014-09-12 | 2020-09-15 | Envision Diagnostics, Inc. | Medical interfaces and other medical devices, systems, and methods for performing eye exams |
| JPWO2016204265A1 (ja) * | 2015-06-18 | 2018-06-14 | 一般財団法人阪大微生物病研究会 | 肺炎球菌補体依存性殺菌能測定方法 |
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| JP2021535921A (ja) | 2018-09-12 | 2021-12-23 | アフィニバックス、インコーポレイテッド | 多価肺炎球菌ワクチン |
| TWI852943B (zh) | 2018-09-12 | 2024-08-21 | 美商兒童醫療中心公司 | 肺炎鏈球菌融合蛋白疫苗 |
| RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
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| ES2330083T3 (es) | 2000-10-27 | 2009-12-04 | Novartis Vaccines And Diagnostics S.R.L. | Acidos nucleicos y proteinas de estreptococos de los grupos a y b. |
| AT410798B (de) | 2001-01-26 | 2003-07-25 | Cistem Biotechnologies Gmbh | Verfahren zur identifizierung, isolierung und herstellung von antigenen gegen ein spezifisches pathogen |
| CA2438921C (en) | 2001-02-21 | 2012-04-10 | Shire Biochem Inc. | Streptococcus pyogenes polypeptides and corresponding dna fragments |
| AU2002306849A1 (en) * | 2001-03-21 | 2002-10-08 | Elitra Pharmaceuticals, Inc. | Identification of essential genes in microorganisms |
| GB0107658D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
| JP2004533236A (ja) | 2001-04-13 | 2004-11-04 | ワイエス | 化膿性連鎖球菌(Streptococcuspyogenes)の表面タンパク質 |
| EP2258842A1 (en) * | 2001-04-16 | 2010-12-08 | Wyeth Holdings Corporation | Streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof |
| FR2824074A1 (fr) | 2001-04-26 | 2002-10-31 | Pasteur Institut | Sequence du genome streptococcus agalactiae, application au developpement de vaccins, d'outils de diagnostic, et a l'identification de cibles therapeutiques |
| EP1450821A1 (en) | 2001-12-07 | 2004-09-01 | Intercell AG | Immunostimulatory oligodeoxynucleotides |
| GB0210128D0 (en) | 2002-05-02 | 2002-06-12 | Chiron Spa | Nucleic acids and proteins from streptococcus groups A & B |
| ES2505695T3 (es) | 2003-07-31 | 2014-10-10 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunógenas para Streptococcus pyogenes |
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2004
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- 2004-04-15 EP EP10178885A patent/EP2311988A1/en not_active Withdrawn
- 2004-04-15 AU AU2004230244A patent/AU2004230244B2/en not_active Ceased
- 2004-04-15 CN CN200480010200XA patent/CN1774447B/zh not_active Expired - Fee Related
- 2004-04-15 EP EP10178893A patent/EP2314718A1/en not_active Withdrawn
- 2004-04-15 EP EP04727537A patent/EP1615950A2/en not_active Withdrawn
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- 2004-04-15 US US10/552,156 patent/US7635487B2/en not_active Expired - Fee Related
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- 2004-04-15 EP EP10178954A patent/EP2311991A1/en not_active Withdrawn
- 2004-04-15 EP EP10178937A patent/EP2333114A1/en not_active Withdrawn
- 2004-04-15 WO PCT/EP2004/003984 patent/WO2004092209A2/en not_active Ceased
- 2004-04-15 CN CN2011100423445A patent/CN102174534A/zh active Pending
- 2004-04-15 EP EP10178902A patent/EP2298934A1/en not_active Withdrawn
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- 2004-04-15 CA CA002522238A patent/CA2522238A1/en not_active Abandoned
- 2004-04-15 EP EP10178910A patent/EP2336357A1/en not_active Withdrawn
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2009
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2010
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2012
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2013
- 2013-01-31 US US13/755,399 patent/US20130136761A1/en not_active Abandoned
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1192241A (zh) * | 1995-06-07 | 1998-09-02 | 生化疫苗公司 | Hsp70家族的链球菌热休克蛋白 |
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|---|---|
| CA2522238A1 (en) | 2004-10-28 |
| WO2004092209A9 (en) | 2008-11-27 |
| AU2004230244A1 (en) | 2004-10-28 |
| US7635487B2 (en) | 2009-12-22 |
| CN1774447A (zh) | 2006-05-17 |
| CN102174534A (zh) | 2011-09-07 |
| EP2298934A1 (en) | 2011-03-23 |
| US8372411B2 (en) | 2013-02-12 |
| US20060263846A1 (en) | 2006-11-23 |
| JP2011004753A (ja) | 2011-01-13 |
| US20100260790A1 (en) | 2010-10-14 |
| EP2314719A1 (en) | 2011-04-27 |
| HK1084958A1 (en) | 2006-08-11 |
| EP2311988A1 (en) | 2011-04-20 |
| WO2004092209A2 (en) | 2004-10-28 |
| WO2004092209A3 (en) | 2004-12-09 |
| EP2333114A1 (en) | 2011-06-15 |
| AU2004230244B2 (en) | 2011-09-22 |
| EP2311987A1 (en) | 2011-04-20 |
| EP1615950A2 (en) | 2006-01-18 |
| EP2311989A1 (en) | 2011-04-20 |
| EP2314718A1 (en) | 2011-04-27 |
| JP2012184236A (ja) | 2012-09-27 |
| EP2311991A1 (en) | 2011-04-20 |
| US20130136761A1 (en) | 2013-05-30 |
| EP2311990A1 (en) | 2011-04-20 |
| JP2007525157A (ja) | 2007-09-06 |
| EP2336357A1 (en) | 2011-06-22 |
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