CN1735433A - 哺乳动物epo模拟ch1缺失模拟体、组合物、方法和用途 - Google Patents

哺乳动物epo模拟ch1缺失模拟体、组合物、方法和用途 Download PDF

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Publication number
CN1735433A
CN1735433A CNA038201100A CN03820110A CN1735433A CN 1735433 A CN1735433 A CN 1735433A CN A038201100 A CNA038201100 A CN A038201100A CN 03820110 A CN03820110 A CN 03820110A CN 1735433 A CN1735433 A CN 1735433A
Authority
CN
China
Prior art keywords
epo mimetic
polypeptide
deleted mimetibodies
mimetibodies
deleted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CNA038201100A
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English (en)
Chinese (zh)
Inventor
G·A·希纳
D·M·奈特
J·格拉耶
B·J·斯卡伦
T·C·内斯珀尔
K·A·库托洛斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Biotech Inc
Original Assignee
Centocor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centocor Inc filed Critical Centocor Inc
Publication of CN1735433A publication Critical patent/CN1735433A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CNA038201100A 2002-06-28 2003-06-30 哺乳动物epo模拟ch1缺失模拟体、组合物、方法和用途 Pending CN1735433A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US39243102P 2002-06-28 2002-06-28
US60/392,431 2002-06-28
US60/412,144 2002-09-19

Publications (1)

Publication Number Publication Date
CN1735433A true CN1735433A (zh) 2006-02-15

Family

ID=30000868

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA038201100A Pending CN1735433A (zh) 2002-06-28 2003-06-30 哺乳动物epo模拟ch1缺失模拟体、组合物、方法和用途

Country Status (6)

Country Link
EP (1) EP1545608A4 (fr)
JP (1) JP2006504406A (fr)
CN (1) CN1735433A (fr)
AU (1) AU2003280130B2 (fr)
CA (1) CA2490409A1 (fr)
WO (1) WO2004002417A2 (fr)

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CA2490409A1 (fr) 2004-01-08
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AU2003280130A1 (en) 2004-01-19
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JP2006504406A (ja) 2006-02-09
AU2003280130B2 (en) 2009-06-11

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