CN1646692A - 在肿瘤中差异表达的基因产物及其用途 - Google Patents

在肿瘤中差异表达的基因产物及其用途 Download PDF

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Publication number
CN1646692A
CN1646692A CNA038074931A CN03807493A CN1646692A CN 1646692 A CN1646692 A CN 1646692A CN A038074931 A CNA038074931 A CN A038074931A CN 03807493 A CN03807493 A CN 03807493A CN 1646692 A CN1646692 A CN 1646692A
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Prior art keywords
nucleic acid
tumor
leu
ser
lys
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CNA038074931A
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Chinese (zh)
Inventor
U·萨因
O·图里斯
M·科斯洛斯基
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Ghanimede Pharmaceutical Co ltd
Biontech SE
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Ganymed Pharmaceuticals GmbH
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Application filed by Ganymed Pharmaceuticals GmbH filed Critical Ganymed Pharmaceuticals GmbH
Priority to CN201310025680.8A priority Critical patent/CN103251952B/zh
Priority to CN201510846314.8A priority patent/CN105396144B/zh
Publication of CN1646692A publication Critical patent/CN1646692A/zh
Granted legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P35/00—Antineoplastic agents
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    • A61P37/02—Immunomodulators
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer

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CNA038074931A 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途 Granted CN1646692A (zh)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201310025680.8A CN103251952B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN201510846314.8A CN105396144B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10211088.3 2002-03-13
DE10211088A DE10211088A1 (de) 2002-03-13 2002-03-13 Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung

Related Child Applications (2)

Application Number Title Priority Date Filing Date
CN201510846314.8A Division CN105396144B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN201310025680.8A Division CN103251952B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途

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CN1646692A true CN1646692A (zh) 2005-07-27

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CNA038074931A Granted CN1646692A (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN201310025680.8A Expired - Lifetime CN103251952B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN201510846314.8A Expired - Lifetime CN105396144B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN03807493.1A Expired - Lifetime CN1646692B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途

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CN201310025680.8A Expired - Lifetime CN103251952B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN201510846314.8A Expired - Lifetime CN105396144B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途
CN03807493.1A Expired - Lifetime CN1646692B (zh) 2002-03-13 2003-03-12 在肿瘤中差异表达的基因产物及其用途

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US (8) US7429461B2 (enExample)
EP (18) EP2287182B1 (enExample)
JP (5) JP4963778B2 (enExample)
KR (4) KR101261887B1 (enExample)
CN (4) CN1646692A (enExample)
AU (2) AU2003219045B2 (enExample)
CA (3) CA2813780C (enExample)
DE (1) DE10211088A1 (enExample)
ES (3) ES2688186T3 (enExample)
IL (4) IL163900A0 (enExample)
MX (1) MXPA04008867A (enExample)
NZ (1) NZ535146A (enExample)
PL (1) PL215160B1 (enExample)
WO (1) WO2003076631A2 (enExample)

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