CN1515541A - 利用非荧光标记检测配体对结合的方法和组合物 - Google Patents

利用非荧光标记检测配体对结合的方法和组合物 Download PDF

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CN1515541A
CN1515541A CNA2004100027867A CN200410002786A CN1515541A CN 1515541 A CN1515541 A CN 1515541A CN A2004100027867 A CNA2004100027867 A CN A2004100027867A CN 200410002786 A CN200410002786 A CN 200410002786A CN 1515541 A CN1515541 A CN 1515541A
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acid
group
substituted
moi
substituted alkyl
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Chinese (zh)
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J
J·范尼斯
��ذ���
J·C·特邦
J·J·豪伯特
��Ĭ����
J·T·默利甘
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LAPJIEN CO
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/167—Mass label
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2565/00—Nucleic acid analysis characterised by mode or means of detection
    • C12Q2565/60—Detection means characterised by use of a special device
    • C12Q2565/627—Detection means characterised by use of a special device being a mass spectrometer

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  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
CNA2004100027867A 1996-01-23 1997-01-23 利用非荧光标记检测配体对结合的方法和组合物 Pending CN1515541A (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1043696P 1996-01-23 1996-01-23
US1540296P 1996-03-21 1996-03-21
US60/010,436 1996-03-21
US60/015,402 1996-03-21

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CNB971925542A Expired - Fee Related CN1159452C (zh) 1996-01-23 1997-01-23 利用非荧光标记检测配体对结合的方法和组合物

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EP (1) EP0850320B1 (cg-RX-API-DMAC7.html)
JP (2) JP2000507091A (cg-RX-API-DMAC7.html)
KR (2) KR100538669B1 (cg-RX-API-DMAC7.html)
CN (2) CN1515541A (cg-RX-API-DMAC7.html)
AT (1) ATE187501T1 (cg-RX-API-DMAC7.html)
AU (1) AU717330B2 (cg-RX-API-DMAC7.html)
BR (1) BR9707060A (cg-RX-API-DMAC7.html)
CA (1) CA2243989A1 (cg-RX-API-DMAC7.html)
CZ (1) CZ218398A3 (cg-RX-API-DMAC7.html)
DE (1) DE69700902T2 (cg-RX-API-DMAC7.html)
ES (1) ES2143848T3 (cg-RX-API-DMAC7.html)
GR (1) GR3032843T3 (cg-RX-API-DMAC7.html)
HU (1) HUP9900459A3 (cg-RX-API-DMAC7.html)
NZ (1) NZ331042A (cg-RX-API-DMAC7.html)
PL (1) PL328272A1 (cg-RX-API-DMAC7.html)
PT (1) PT850320E (cg-RX-API-DMAC7.html)
WO (1) WO1997027327A2 (cg-RX-API-DMAC7.html)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108490093A (zh) * 2018-03-29 2018-09-04 曲阜师范大学 一种开关型硫醇荧光标记试剂的荧光检测应用及其合成方法
CN112240915A (zh) * 2019-07-19 2021-01-19 杭州盛弗泰新材料科技有限公司 一种5-氨基-1h-1，2，4-三氮唑-3-羧酸的高效液相色谱检测方法
CN112816578A (zh) * 2020-12-30 2021-05-18 上海市农业科学院 一种含氨基小分子蘑菇毒素的检测方法以及一种试剂盒
CN112881491A (zh) * 2021-02-05 2021-06-01 深圳大学 一种生物传感器电极的制备方法和葡萄糖生物传感器
CN117535045A (zh) * 2023-07-12 2024-02-09 中国热带农业科学院分析测试中心 一种痕量噻虫嗪检测用Zn-MOF@Au NPS/DNA适配体荧光探针及其制备方法

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Cited By (8)

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Publication number Priority date Publication date Assignee Title
CN108490093A (zh) * 2018-03-29 2018-09-04 曲阜师范大学 一种开关型硫醇荧光标记试剂的荧光检测应用及其合成方法
CN112240915A (zh) * 2019-07-19 2021-01-19 杭州盛弗泰新材料科技有限公司 一种5-氨基-1h-1，2，4-三氮唑-3-羧酸的高效液相色谱检测方法
CN112240915B (zh) * 2019-07-19 2022-08-12 杭州盛弗泰新材料科技有限公司 一种5-氨基-1h-1，2，4-三氮唑-3-羧酸的高效液相色谱检测方法
CN112816578A (zh) * 2020-12-30 2021-05-18 上海市农业科学院 一种含氨基小分子蘑菇毒素的检测方法以及一种试剂盒
CN112816578B (zh) * 2020-12-30 2021-09-24 上海市农业科学院 一种含氨基小分子蘑菇毒素的检测方法以及一种试剂盒
CN112881491A (zh) * 2021-02-05 2021-06-01 深圳大学 一种生物传感器电极的制备方法和葡萄糖生物传感器
CN117535045A (zh) * 2023-07-12 2024-02-09 中国热带农业科学院分析测试中心 一种痕量噻虫嗪检测用Zn-MOF@Au NPS/DNA适配体荧光探针及其制备方法
CN117535045B (zh) * 2023-07-12 2024-05-31 中国热带农业科学院分析测试中心 一种痕量噻虫嗪检测用Zn-MOF@Au NPS/DNA适配体荧光探针及其制备方法

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KR19990081923A (ko) 1999-11-15
JP2008220370A (ja) 2008-09-25
PL328272A1 (en) 1999-01-18
KR20040081811A (ko) 2004-09-22
AU717330B2 (en) 2000-03-23
PT850320E (pt) 2000-05-31
DE69700902D1 (de) 2000-01-13
KR100473903B1 (ko) 2005-09-30
WO1997027327A2 (en) 1997-07-31
HUP9900459A2 (hu) 1999-06-28
CA2243989A1 (en) 1997-07-31
CN1159452C (zh) 2004-07-28
ES2143848T3 (es) 2000-05-16
KR100538669B1 (ko) 2005-12-26
GR3032843T3 (en) 2000-07-31
CN1212019A (zh) 1999-03-24
EP0850320A2 (en) 1998-07-01
JP2000507091A (ja) 2000-06-13
BR9707060A (pt) 1999-12-28
DE69700902T2 (de) 2000-07-20
NZ331042A (en) 1999-10-28
EP0850320B1 (en) 1999-12-08
HUP9900459A3 (en) 1999-11-29
ATE187501T1 (de) 1999-12-15
CZ218398A3 (cs) 1998-12-16
WO1997027327A3 (en) 1997-11-20
AU1707997A (en) 1997-08-20

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