CN1440462A - 鉴定和生产抗原肽的方法并且将其用作疫苗 - Google Patents

鉴定和生产抗原肽的方法并且将其用作疫苗 Download PDF

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CN1440462A
CN1440462A CN01812119A CN01812119A CN1440462A CN 1440462 A CN1440462 A CN 1440462A CN 01812119 A CN01812119 A CN 01812119A CN 01812119 A CN01812119 A CN 01812119A CN 1440462 A CN1440462 A CN 1440462A
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epi
virus
cell
vaccine
antigen
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约翰·J·L·西马德
戴维·C·戴蒙德
雷向东
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Mannkind Corp
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Mannkind Corp
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
CN01812119A 2000-04-28 2001-04-27 鉴定和生产抗原肽的方法并且将其用作疫苗 Pending CN1440462A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US56157100A 2000-04-28 2000-04-28
US56046500A 2000-04-28 2000-04-28
US56157200A 2000-04-28 2000-04-28
US09/561,572 2000-04-28
US09/561,074 2000-04-28
US09/561,571 2000-04-28
US09/561,074 US6861234B1 (en) 2000-04-28 2000-04-28 Method of epitope discovery
US09/560,465 2000-04-28

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Publication Number Publication Date
CN1440462A true CN1440462A (zh) 2003-09-03

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CN01812119A Pending CN1440462A (zh) 2000-04-28 2001-04-27 鉴定和生产抗原肽的方法并且将其用作疫苗

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US (1) US20070269464A1 (enExample)
EP (4) EP1276896B1 (enExample)
JP (1) JP2003535824A (enExample)
CN (1) CN1440462A (enExample)
AT (1) ATE474931T1 (enExample)
AU (3) AU2001257410B8 (enExample)
CA (1) CA2405363A1 (enExample)
DE (1) DE60142615D1 (enExample)
DK (1) DK1276896T3 (enExample)
ES (1) ES2347762T3 (enExample)
NZ (1) NZ521715A (enExample)
WO (1) WO2001082963A2 (enExample)

Cited By (16)

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CN101246176B (zh) * 2007-02-13 2013-06-05 许洋 鳞状细胞癌抗原阴性宫颈癌血清蛋白质检测的质谱试剂及其制备方法
CN104761644A (zh) * 2014-01-03 2015-07-08 百奇生物科技（苏州）有限公司 大肠杆菌表达的融合蛋白mbp-mart-1及其制备和应用
CN105067731A (zh) * 2015-06-05 2015-11-18 中国农业科学院兰州兽医研究所 一种弓形虫感染后血清中生物标记物的筛选方法及筛选出的生物标记物的应用
CN105175498A (zh) * 2015-10-09 2015-12-23 深圳市康尔诺生物技术有限公司 一种宫颈癌相关的热休克蛋白复合物及其应用
CN105682679A (zh) * 2013-11-01 2016-06-15 辉瑞公司 用于表达前列腺相关抗原的载体
CN108603171A (zh) * 2015-12-23 2018-09-28 基因医疗免疫疗法有限责任公司 新一代抗原-特异性tcr
CN110187122A (zh) * 2012-09-05 2019-08-30 亚利桑那州评议委员会,亚利桑那州法人团体,代理和代表亚利桑那州立大学 发现治疗靶标的方法
CN110291402A (zh) * 2016-06-27 2019-09-27 朱诺治疗学股份有限公司 鉴定肽表位的方法、结合此类表位的分子和相关用途
CN110809580A (zh) * 2017-01-24 2020-02-18 安贝科思生物制剂公司 用于靶向癌症中包含非典型hla-i和新抗原的复合体的方法和组合物
CN111529697A (zh) * 2011-05-26 2020-08-14 金纽斯生物科技投资有限责任公司 调节的免疫优势疗法
CN113484523A (zh) * 2015-02-12 2021-10-08 生物技术Rna制药有限公司 预测可用于疫苗接种的t细胞表位
CN113549153A (zh) * 2014-05-29 2021-10-26 宏观基因有限公司 三特异性结合分子和其使用方法
CN114729361A (zh) * 2019-11-15 2022-07-08 上海细胞治疗集团有限公司 一种在活化的t细胞中具有高活性的启动子
CN115916248A (zh) * 2020-03-03 2023-04-04 穆罕默德·塔雷克 Custommune：设计个性化和群体靶向肽疫苗的网络工具
US12270813B2 (en) 2017-06-09 2025-04-08 BioNTech SE Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
US12618066B2 (en) 2019-11-15 2026-05-05 Shanghai Cell Therapy Group Co., Ltd. Promoter having high activity in activated T-cell

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Cited By (19)

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Publication number Priority date Publication date Assignee Title
CN101246176B (zh) * 2007-02-13 2013-06-05 许洋 鳞状细胞癌抗原阴性宫颈癌血清蛋白质检测的质谱试剂及其制备方法
CN111529697A (zh) * 2011-05-26 2020-08-14 金纽斯生物科技投资有限责任公司 调节的免疫优势疗法
CN110187122A (zh) * 2012-09-05 2019-08-30 亚利桑那州评议委员会,亚利桑那州法人团体,代理和代表亚利桑那州立大学 发现治疗靶标的方法
CN105682679B (zh) * 2013-11-01 2020-12-08 辉瑞公司 用于表达前列腺相关抗原的载体
CN105682679A (zh) * 2013-11-01 2016-06-15 辉瑞公司 用于表达前列腺相关抗原的载体
CN104761644A (zh) * 2014-01-03 2015-07-08 百奇生物科技（苏州）有限公司 大肠杆菌表达的融合蛋白mbp-mart-1及其制备和应用
CN113549153A (zh) * 2014-05-29 2021-10-26 宏观基因有限公司 三特异性结合分子和其使用方法
CN113484523A (zh) * 2015-02-12 2021-10-08 生物技术Rna制药有限公司 预测可用于疫苗接种的t细胞表位
CN105067731A (zh) * 2015-06-05 2015-11-18 中国农业科学院兰州兽医研究所 一种弓形虫感染后血清中生物标记物的筛选方法及筛选出的生物标记物的应用
CN105175498A (zh) * 2015-10-09 2015-12-23 深圳市康尔诺生物技术有限公司 一种宫颈癌相关的热休克蛋白复合物及其应用
CN108603171A (zh) * 2015-12-23 2018-09-28 基因医疗免疫疗法有限责任公司 新一代抗原-特异性tcr
CN110291402A (zh) * 2016-06-27 2019-09-27 朱诺治疗学股份有限公司 鉴定肽表位的方法、结合此类表位的分子和相关用途
CN110291402B (zh) * 2016-06-27 2023-09-01 朱诺治疗学股份有限公司 鉴定肽表位的方法、结合此类表位的分子和相关用途
CN110809580A (zh) * 2017-01-24 2020-02-18 安贝科思生物制剂公司 用于靶向癌症中包含非典型hla-i和新抗原的复合体的方法和组合物
US12270813B2 (en) 2017-06-09 2025-04-08 BioNTech SE Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
CN114729361A (zh) * 2019-11-15 2022-07-08 上海细胞治疗集团有限公司 一种在活化的t细胞中具有高活性的启动子
CN114729361B (zh) * 2019-11-15 2024-05-03 上海细胞治疗集团股份有限公司 一种在活化的t细胞中具有高活性的启动子
US12618066B2 (en) 2019-11-15 2026-05-05 Shanghai Cell Therapy Group Co., Ltd. Promoter having high activity in activated T-cell
CN115916248A (zh) * 2020-03-03 2023-04-04 穆罕默德·塔雷克 Custommune：设计个性化和群体靶向肽疫苗的网络工具

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EP1276896B1 (en) 2010-07-21
EP2248910A1 (en) 2010-11-10
AU2001257410B2 (en) 2006-08-24
AU2010251790B2 (en) 2013-02-07
WO2001082963A2 (en) 2001-11-08
JP2003535824A (ja) 2003-12-02
CA2405363A1 (en) 2001-11-08
EP1276896A2 (en) 2003-01-22
DK1276896T3 (da) 2010-10-18
AU5741001A (en) 2001-11-12
AU2001257410B9 (en) 2006-10-05
ES2347762T3 (es) 2010-11-04
EP2278024A1 (en) 2011-01-26
EP2278023A1 (en) 2011-01-26
WO2001082963A3 (en) 2002-04-11
HK1053333A1 (en) 2003-10-17
AU2010251790A1 (en) 2011-01-06
ATE474931T1 (de) 2010-08-15
AU2001257410B8 (en) 2006-12-21
DE60142615D1 (de) 2010-09-02
US20070269464A1 (en) 2007-11-22

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