DK1276896T3 - Epitop-synkronisering i antigen-præsenterende celler - Google Patents

Epitop-synkronisering i antigen-præsenterende celler

Info

Publication number
DK1276896T3
DK1276896T3 DK01930922.8T DK01930922T DK1276896T3 DK 1276896 T3 DK1276896 T3 DK 1276896T3 DK 01930922 T DK01930922 T DK 01930922T DK 1276896 T3 DK1276896 T3 DK 1276896T3
Authority
DK
Denmark
Prior art keywords
housekeeping
disclosed
antigen
cells
presenting cells
Prior art date
Application number
DK01930922.8T
Other languages
English (en)
Inventor
John J L Simard
David C Diamond
Xiang-Dong Lei
Original Assignee
Mannkind Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/561,074 external-priority patent/US6861234B1/en
Application filed by Mannkind Corp filed Critical Mannkind Corp
Application granted granted Critical
Publication of DK1276896T3 publication Critical patent/DK1276896T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515Animal cells
    • A61K2039/5158Antigen-pulsed cells, e.g. T-cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pyrane Compounds (AREA)
DK01930922.8T 2000-04-28 2001-04-27 Epitop-synkronisering i antigen-præsenterende celler DK1276896T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US56046500A 2000-04-28 2000-04-28
US56157100A 2000-04-28 2000-04-28
US56157200A 2000-04-28 2000-04-28
US09/561,074 US6861234B1 (en) 2000-04-28 2000-04-28 Method of epitope discovery
PCT/US2001/013806 WO2001082963A2 (en) 2000-04-28 2001-04-27 Method of identifying and producing antigen peptides and use thereof as vaccines

Publications (1)

Publication Number Publication Date
DK1276896T3 true DK1276896T3 (da) 2010-10-18

Family

ID=27504814

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01930922.8T DK1276896T3 (da) 2000-04-28 2001-04-27 Epitop-synkronisering i antigen-præsenterende celler

Country Status (13)

Country Link
US (1) US20070269464A1 (da)
EP (4) EP2278023A1 (da)
JP (1) JP2003535824A (da)
CN (1) CN1440462A (da)
AT (1) ATE474931T1 (da)
AU (3) AU2001257410B8 (da)
CA (1) CA2405363A1 (da)
DE (1) DE60142615D1 (da)
DK (1) DK1276896T3 (da)
ES (1) ES2347762T3 (da)
HK (1) HK1053333A1 (da)
NZ (1) NZ521715A (da)
WO (1) WO2001082963A2 (da)

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EP1595548A3 (en) * 2001-03-07 2006-02-22 Mannkind Corporation Anti-neovasculature preparations for treating cancer
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DE60238864D1 (de) * 2001-11-07 2011-02-17 Mankind Corp Für epitope von antigenen kodierende expressionsvektoren und verfahren zu deren konzeption
AU2008229888B2 (en) * 2001-11-07 2012-07-05 Mannkind Corporation Expression vectors encoding epitopes of target-associated antigens and methods for their design
MXPA05002455A (es) * 2002-09-06 2005-06-03 Mannkind Corp Secuencias de epitopes.
CN102370974B (zh) 2002-12-16 2014-09-17 全球免疫股份有限公司 用于免疫治疗的基于酵母的疫苗
US8343502B2 (en) 2002-12-16 2013-01-01 Globeimmune, Inc. Yeast-based vaccines as immunotherapy
ATE496129T1 (de) * 2003-07-22 2011-02-15 Ludwig Inst Cancer Res Von hla-klasse-ii-molekülen präsentierte ssx-2- peptide
CA2592968A1 (en) * 2004-12-29 2006-07-06 Mannkind Corporation Use of compositions comprising various tumor-associated antigens as anti-cancer vaccines
SG158155A1 (en) * 2004-12-29 2010-01-29 Mannkind Corp Methods to bypass cd+4 cells in the induction of an immune response
SG162817A1 (en) 2005-06-17 2010-07-29 Mannkind Corp Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma
NZ564360A (en) * 2005-06-17 2011-03-31 Mannkind Corp Immunogenic product comprising a nucleic acid capable of expressing a PRAME epitope and a PSMA epitope and a peptide composition
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WO2012031076A1 (en) * 2010-09-02 2012-03-08 Ludwig Institute For Cancer Research, Ltd. Recombinant trypanosoma cruzi cells useful as anti-cancer immune agents
EP2714072A1 (en) * 2011-05-26 2014-04-09 Geneius Biotechnology Investments, LLC Modulated immunodominance therapy
EP3604634A1 (en) * 2012-09-05 2020-02-05 Arizona Board of Regents, a Body Corporate of the State of Arizona, acting for and on behalf of Arizona State University Methods for discovering therapeutic targets
EP3607974A1 (en) * 2013-03-15 2020-02-12 The Trustees of The University of Pennsylvania Cancer vaccines and methods of treatment using the same
EP3524262A1 (en) * 2013-11-01 2019-08-14 Pfizer Inc Vectors for expression of prostate-associated antigens
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WO2015149010A1 (en) * 2014-03-28 2015-10-01 University Of Washington Through Its Center For Commercialization Methods of identifying antigens for vaccines
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WO2016128060A1 (en) * 2015-02-12 2016-08-18 Biontech Ag Predicting t cell epitopes useful for vaccination
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KR20180050321A (ko) 2015-08-07 2018-05-14 이미지냅 인코포레이티드 분자를 표적화하기 위한 항원 결합 구조체
CN105175498A (zh) * 2015-10-09 2015-12-23 深圳市康尔诺生物技术有限公司 一种宫颈癌相关的热休克蛋白复合物及其应用
EP3383427A4 (en) 2015-12-04 2019-11-27 Mayo Foundation for Medical Education and Research METHODS AND VACCINES FOR INDUCING IMMUNE RESPONSES OF MULTIPLE DIFFERENT CMH MOLECULES
BR112018012826A2 (pt) * 2015-12-23 2018-12-04 Medigene Immunotherapies Gmbh método para gerar linfócitos, para gerar um tcr e tcr específico para gage-1
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CN110809580A (zh) * 2017-01-24 2020-02-18 安贝科思生物制剂公司 用于靶向癌症中包含非典型hla-i和新抗原的复合体的方法和组合物
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CN112813099A (zh) * 2019-11-15 2021-05-18 上海细胞治疗集团有限公司 一种在活化的t细胞中具有高活性的启动子
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Also Published As

Publication number Publication date
WO2001082963A3 (en) 2002-04-11
AU2010251790A1 (en) 2011-01-06
US20070269464A1 (en) 2007-11-22
AU2001257410B8 (en) 2006-12-21
EP1276896A2 (en) 2003-01-22
AU2001257410B2 (en) 2006-08-24
JP2003535824A (ja) 2003-12-02
EP2248910A1 (en) 2010-11-10
CA2405363A1 (en) 2001-11-08
AU2010251790B2 (en) 2013-02-07
HK1053333A1 (en) 2003-10-17
EP1276896B1 (en) 2010-07-21
EP2278024A1 (en) 2011-01-26
AU2001257410B9 (en) 2006-10-05
ES2347762T3 (es) 2010-11-04
ATE474931T1 (de) 2010-08-15
NZ521715A (en) 2008-01-31
WO2001082963A2 (en) 2001-11-08
EP2278023A1 (en) 2011-01-26
AU5741001A (en) 2001-11-12
DE60142615D1 (de) 2010-09-02
CN1440462A (zh) 2003-09-03

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