DK1216053T3 - Influenzavaccine - Google Patents
InfluenzavaccineInfo
- Publication number
- DK1216053T3 DK1216053T3 DK00966084T DK00966084T DK1216053T3 DK 1216053 T3 DK1216053 T3 DK 1216053T3 DK 00966084 T DK00966084 T DK 00966084T DK 00966084 T DK00966084 T DK 00966084T DK 1216053 T3 DK1216053 T3 DK 1216053T3
- Authority
- DK
- Denmark
- Prior art keywords
- antigen
- influenza vaccine
- vaccine
- dose
- combination
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/543—Mucosal route intranasal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16211—Influenzavirus B, i.e. influenza B virus
- C12N2760/16251—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9923176.3A GB9923176D0 (en) | 1999-09-30 | 1999-09-30 | Novel composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1216053T3 true DK1216053T3 (da) | 2006-03-20 |
Family
ID=10861908
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05077465.2T DK1618889T3 (da) | 1999-09-30 | 2000-09-27 | Influenzavaccine |
DK00966084T DK1216053T3 (da) | 1999-09-30 | 2000-09-27 | Influenzavaccine |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05077465.2T DK1618889T3 (da) | 1999-09-30 | 2000-09-27 | Influenzavaccine |
Country Status (15)
Country | Link |
---|---|
US (2) | US7238349B1 (da) |
EP (4) | EP3103473A1 (da) |
JP (4) | JP2003510291A (da) |
AT (2) | ATE499113T1 (da) |
AU (1) | AU774921B2 (da) |
BR (1) | BR0014386A (da) |
CA (2) | CA2616210C (da) |
CY (2) | CY1111908T1 (da) |
DE (3) | DE60045668D1 (da) |
DK (2) | DK1618889T3 (da) |
ES (2) | ES2359982T3 (da) |
GB (1) | GB9923176D0 (da) |
HK (1) | HK1048434B (da) |
PT (1) | PT1618889E (da) |
WO (1) | WO2001022992A2 (da) |
Families Citing this family (96)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1678345A (zh) | 2002-04-26 | 2005-10-05 | 米迪缪尼疫苗股份有限公司 | 制备流感病毒的多质粒系统 |
US7465456B2 (en) | 2002-04-26 | 2008-12-16 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
US20050106178A1 (en) * | 2003-01-30 | 2005-05-19 | Chiron Corporation | Adjuvanted influenza vaccine |
US20060110406A1 (en) | 2003-02-25 | 2006-05-25 | Medimmune Vaccines, Inc. | Refrigerator-temperature stable influenza vaccine compositions |
KR101251902B1 (ko) | 2003-02-25 | 2013-04-08 | 메디뮨 엘엘씨 | 인플루엔자 백신 조성물의 제조 방법 |
AU2012201973B2 (en) * | 2003-02-25 | 2014-05-22 | Medimmune, Llc | Methods of producing influenza vaccine compositions |
TWI350174B (en) * | 2003-03-12 | 2011-10-11 | Wyeth Corp | Adjuvanted bovine vaccines |
AU2004308328B2 (en) | 2003-12-23 | 2009-06-04 | Medimmune, Llc | Multi plasmid system for the production of influenza virus |
US20080254065A1 (en) | 2004-03-09 | 2008-10-16 | Chiron Corporation | Influenza Virus Vaccines |
DE602005024827D1 (de) | 2004-09-09 | 2010-12-30 | Novartis Vaccines & Diagnostic | Verminderung von potentiellen iatrogenen risiken in verbindung mit influenza impfstoffen |
JP2008519042A (ja) | 2004-11-03 | 2008-06-05 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | インフルエンザワクチン接種 |
US20090028903A1 (en) * | 2005-03-23 | 2009-01-29 | Glaxosmithkline Biologicals, S.A. | Novel use |
AU2006226458B2 (en) * | 2005-03-23 | 2012-08-30 | Glaxosmithkline Biologicals S.A. | Novel composition |
US11707520B2 (en) | 2005-11-03 | 2023-07-25 | Seqirus UK Limited | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
NZ568212A (en) | 2005-11-04 | 2012-03-30 | Novartis Vaccines & Diagnostic | Changing Th1/Th2 balance in split influenza vaccines with adjuvants |
US20110180430A1 (en) | 2005-11-04 | 2011-07-28 | Novartis Vaccines And Diagnostics Srl | Adjuvanted influenza vaccines including cytokine-inducing agents |
CN102727885A (zh) | 2005-11-04 | 2012-10-17 | 诺华疫苗和诊断有限公司 | 包含颗粒佐剂和免疫增强剂组合的流感疫苗 |
JP2009514844A (ja) | 2005-11-04 | 2009-04-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | スプリットインフルエンザワクチン用のアジュバントとしての遊離水相界面活性剤を含むエマルション |
EP1945253A2 (en) * | 2005-11-04 | 2008-07-23 | Novartis Vaccines and Diagnostics S.r.l. | Adminstration routes for priming/boosting with influenza vaccines |
CA2628152C (en) | 2005-11-04 | 2016-02-02 | Novartis Vaccines And Diagnostics S.R.L. | Adjuvanted vaccines with non-virion antigens prepared from influenza viruses grown in cell culture |
EP1957104B1 (en) * | 2005-11-04 | 2012-03-21 | Novartis Vaccines and Diagnostics S.r.l. | Influenza vaccines extemporaneously adsorbed to aluminium adjuvants |
WO2007052155A2 (en) | 2005-11-04 | 2007-05-10 | Novartis Vaccines And Diagnostics Srl | Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant |
KR20110110853A (ko) | 2006-01-27 | 2011-10-07 | 노파르티스 파르마 아게 | 적혈구응집소 및 기질 단백질을 함유한 인플루엔자 백신 |
CA2646349A1 (en) | 2006-03-24 | 2007-10-04 | Novartis Vaccines And Diagnostics Gmbh & Co Kg | Storage of influenza vaccines without refrigeration |
US9072701B2 (en) * | 2006-04-21 | 2015-07-07 | St. Jude Children's Research Hospital | Avian influenza viruses, vaccines, compositions, formulations, and methods |
US20100015168A1 (en) | 2006-06-09 | 2010-01-21 | Novartis Ag | Immunogenic compositions for streptococcus agalactiae |
JP5566687B2 (ja) * | 2006-06-15 | 2014-08-06 | ノバルティス アーゲー | アジュバントを使用しない複数回投与ワクチン接種レジメン |
US20080014217A1 (en) * | 2006-07-17 | 2008-01-17 | Emmanuel Jules Hanon | Influenza vaccine |
KR101696727B1 (ko) | 2006-07-17 | 2017-01-16 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 인플루엔자 백신 |
DK2043682T3 (da) * | 2006-07-17 | 2014-06-02 | Glaxosmithkline Biolog Sa | Influenzavaccine |
CA2583555C (en) * | 2006-07-17 | 2020-01-07 | Glaxosmithkline Biologicals S.A. | Influenza vaccine |
GB0614460D0 (en) | 2006-07-20 | 2006-08-30 | Novartis Ag | Vaccines |
EP3456348A1 (en) | 2006-09-11 | 2019-03-20 | Seqirus UK Limited | Making influenza virus vaccines without using eggs |
US20100183667A1 (en) | 2006-10-12 | 2010-07-22 | Glaxo Smithkline Biologicals S.A. | Vaccine Comprising an Oil in Water Emulsion Adjuvant |
GB0622282D0 (en) | 2006-11-08 | 2006-12-20 | Novartis Ag | Quality control methods |
CA2671629C (en) | 2006-12-06 | 2017-08-15 | Novartis Ag | Vaccines including antigen from four strains of influenza virus |
PE20090146A1 (es) | 2007-04-20 | 2009-03-23 | Glaxosmithkline Biolog Sa | Composicion inmunogenica contra el virus influenza |
EP2674486A1 (en) | 2007-06-18 | 2013-12-18 | MedImmune, LLC | Influenza B viruses having alterations in the hemaglutinin polypeptide |
CN101085348B (zh) * | 2007-06-18 | 2010-08-18 | 南京农业大学 | 用于禽流感灭活抗原的鼻腔免疫复合佐剂 |
CA2692200A1 (en) | 2007-06-27 | 2008-12-31 | Novartis Ag | Low-additive influenza vaccines |
WO2009006420A2 (en) * | 2007-06-29 | 2009-01-08 | Avianax, Llc | Vaccine production for pathogenic bird viral diseases |
US8084594B2 (en) * | 2007-07-13 | 2011-12-27 | The United States Of America As Represented By The Secretary Of Agriculture | H2N3 influenza A viruses and methods of use |
WO2009039628A1 (en) | 2007-09-27 | 2009-04-02 | Immunovaccine Technologies Inc. | Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo |
US20100209452A1 (en) * | 2007-10-03 | 2010-08-19 | Immunovaccine Technologies, Inc | Compositions comprising an antigen, an amphipathic compound and a hydrophobic carrier, and uses thereof |
GB0810305D0 (en) | 2008-06-05 | 2008-07-09 | Novartis Ag | Influenza vaccination |
EP2227251A1 (en) | 2007-12-06 | 2010-09-15 | GlaxoSmithKline Biologicals SA | Influenza composition |
GB0818453D0 (en) | 2008-10-08 | 2008-11-12 | Novartis Ag | Fermentation processes for cultivating streptococci and purification processes for obtaining cps therefrom |
WO2009081172A1 (en) | 2007-12-24 | 2009-07-02 | Novartis Ag | Assays for adsorbed influenza vaccines |
US20120034266A1 (en) * | 2008-03-04 | 2012-02-09 | Nel Andre E | Methods and compositions for improving immune response by a nutraceutical antioxidant |
EP2589392B1 (en) | 2008-03-05 | 2016-11-30 | Sanofi Pasteur | Process for stabilizing an adjuvant containing vaccine composition |
AU2009227674C1 (en) | 2008-03-18 | 2015-01-29 | Seqirus UK Limited | Improvements in preparation of influenza virus vaccine antigens |
EP3023107A1 (en) * | 2008-04-21 | 2016-05-25 | Nanobio Corporation | Nanoemulsion influenza vaccine |
JP5715051B2 (ja) | 2008-06-05 | 2015-05-07 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | リポソーム、抗原、ポリヌクレオチド及び疎水性物質の連続相を含む担体を含む組成物 |
CA2729248A1 (en) | 2008-06-25 | 2009-12-30 | Novartis Ag | Rapid responses to delayed booster immunisations |
JP5689796B2 (ja) | 2008-08-01 | 2015-03-25 | ガマ ワクチンズ ピーティワイ リミテッド | インフルエンザワクチン |
PL2396032T3 (pl) | 2009-02-10 | 2017-05-31 | Seqirus UK Limited | Szczepionki przeciw grypie o obniżonych zawartościach skwalenu |
CA2756522C (en) | 2009-03-24 | 2018-06-26 | Novartis Ag | Adjuvanting meningococcal factor h binding protein |
BE1019643A3 (fr) | 2009-04-27 | 2012-09-04 | Novartis Ag | Vaccins de protection contre la grippe. |
CN103764160A (zh) | 2009-05-29 | 2014-04-30 | 诺华有限公司 | 流感病毒血凝素试验 |
EP2475385A1 (en) | 2009-09-10 | 2012-07-18 | Novartis AG | Combination vaccines against respiratory tract diseases |
US9341623B2 (en) * | 2009-09-25 | 2016-05-17 | Glaxosmithkline Biologicals Sa | Immunodiffusion assay for influenza virus |
MX2012004067A (es) | 2009-10-09 | 2012-08-03 | Cbio Ltd | Variantes de la chaperonina 10. |
DE102009056884B4 (de) * | 2009-12-03 | 2021-03-18 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
DE102009056883B4 (de) | 2009-12-03 | 2012-08-16 | Novartis Ag | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
DE102009056871A1 (de) | 2009-12-03 | 2011-06-22 | Novartis AG, 4056 | Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben |
CN102858322B (zh) | 2009-12-03 | 2015-04-29 | 诺华股份有限公司 | 疫苗佐剂制备中的亲水过滤 |
NZ600323A (en) | 2009-12-03 | 2013-12-20 | Novartis Ag | Circulation of components during microfluidization and/or homogenization emulsions |
CL2012001399A1 (es) | 2009-12-03 | 2013-03-08 | Novartis Ag | Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion. |
KR101643918B1 (ko) | 2009-12-03 | 2016-07-29 | 노파르티스 아게 | 미세 액화를 위한 상호작용 및 배압 챔버의 배치 |
ES2597158T5 (es) | 2010-05-12 | 2020-03-26 | Novartis Ag | Procedimientos mejorados para preparar escualeno |
WO2012032482A1 (en) | 2010-09-07 | 2012-03-15 | Novartis Ag | Generic assays for detection of mammalian reovirus |
US9821051B1 (en) | 2010-10-28 | 2017-11-21 | Seqirus UK Limited | Reducing hospitalization in elderly influenza vaccine recipients |
EP2667891B1 (en) | 2011-01-27 | 2021-10-06 | Gamma Vaccines Pty Limited | Combination vaccines |
JP6240077B2 (ja) | 2011-10-06 | 2017-11-29 | イムノバクシーン・テクノロジーズ・インコーポレイテッドImmunovaccine Technologies Inc. | Tlr2を活性化するか、またはその活性を増加させるアジュバントを含むリポソーム組成物およびその使用 |
US20140335507A1 (en) | 2011-12-12 | 2014-11-13 | Novartis Ag | Assays for influenza virus hemagglutinins |
EP2797624A1 (en) | 2011-12-29 | 2014-11-05 | Novartis AG | Adjuvanted combinations of meningococcal factor h binding proteins |
KR102055176B1 (ko) | 2012-03-23 | 2019-12-12 | 피트니 파마슈티컬스 피티와이 리미티드 | 암 치료용 키나제 저해제 |
CA2875683A1 (en) | 2012-06-05 | 2013-12-12 | The Australian National University | Vaccination with interleukin-4 antagonists |
EP2880154B1 (en) | 2012-08-03 | 2019-05-15 | Sanofi Pasteur SA | Production of infectious influenza viruses |
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1999
- 1999-09-30 GB GBGB9923176.3A patent/GB9923176D0/en not_active Ceased
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2000
- 2000-09-27 DE DE60045668T patent/DE60045668D1/de not_active Expired - Lifetime
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- 2000-09-27 DE DE201112100035 patent/DE122011100035I1/de active Pending
- 2000-09-27 EP EP15197199.1A patent/EP3103473A1/en not_active Withdrawn
- 2000-09-27 JP JP2001526201A patent/JP2003510291A/ja active Pending
- 2000-09-27 AT AT05077465T patent/ATE499113T1/de active
- 2000-09-27 DK DK05077465.2T patent/DK1618889T3/da active
- 2000-09-27 PT PT05077465T patent/PT1618889E/pt unknown
- 2000-09-27 DE DE60024112T patent/DE60024112T2/de not_active Expired - Lifetime
- 2000-09-27 BR BR0014386-3A patent/BR0014386A/pt not_active Application Discontinuation
- 2000-09-27 EP EP05077465A patent/EP1618889B8/en not_active Expired - Lifetime
- 2000-09-27 EP EP00966084A patent/EP1216053B1/en not_active Revoked
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