CN1409720A - 氨基烷基氨基葡糖苷磷酸酯化合物及其作为佐剂和免疫效应物的用途 - Google Patents

氨基烷基氨基葡糖苷磷酸酯化合物及其作为佐剂和免疫效应物的用途 Download PDF

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Publication number
CN1409720A
CN1409720A CN00816859A CN00816859A CN1409720A CN 1409720 A CN1409720 A CN 1409720A CN 00816859 A CN00816859 A CN 00816859A CN 00816859 A CN00816859 A CN 00816859A CN 1409720 A CN1409720 A CN 1409720A
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China
Prior art keywords
compound
mmol
phosphono
deoxy
attached
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Pending
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CN00816859A
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English (en)
Chinese (zh)
Inventor
D·A·约翰逊
C·G·索厄尔
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Corixa Corp
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Corixa Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN00816859A 1999-11-12 2000-11-13 氨基烷基氨基葡糖苷磷酸酯化合物及其作为佐剂和免疫效应物的用途 Pending CN1409720A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/439,839 1999-11-12
US09/439,839 US6303347B1 (en) 1997-05-08 1999-11-12 Aminoalkyl glucosaminide phosphate compounds and their use as adjuvants and immunoeffectors

Publications (1)

Publication Number Publication Date
CN1409720A true CN1409720A (zh) 2003-04-09

Family

ID=23746342

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00816859A Pending CN1409720A (zh) 1999-11-12 2000-11-13 氨基烷基氨基葡糖苷磷酸酯化合物及其作为佐剂和免疫效应物的用途

Country Status (12)

Country Link
US (1) US6303347B1 (enExample)
EP (1) EP1230250A2 (enExample)
JP (1) JP2003514783A (enExample)
CN (1) CN1409720A (enExample)
AR (1) AR026443A1 (enExample)
BR (1) BR0015501A (enExample)
CA (1) CA2391299A1 (enExample)
CO (1) CO5261562A1 (enExample)
MX (1) MXPA02004774A (enExample)
NO (1) NO20022207L (enExample)
NZ (1) NZ518860A (enExample)
WO (1) WO2001034617A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106456546A (zh) * 2014-03-12 2017-02-22 葛兰素史密丝克莱恩生物有限公司 用于黏膜递送的脂质体组合物

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