CN1391473A - Vla－4抑制剂化合物 - Google Patents

Vla－4抑制剂化合物 Download PDF

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Publication number
CN1391473A
CN1391473A CN00809510A CN00809510A CN1391473A CN 1391473 A CN1391473 A CN 1391473A CN 00809510 A CN00809510 A CN 00809510A CN 00809510 A CN00809510 A CN 00809510A CN 1391473 A CN1391473 A CN 1391473A
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China
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group
mixture
replacement
methoxyl group
pyrrolidinyl
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CN00809510A
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Chinese (zh)
Inventor
J·J·巴德温
E·麦当娜德
K·J·莫里尔蒂
C·R·撒尔科
町永信雄
中山敦
千叶淳
饭村信
米田贺行
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Daiichi Pharmaceutical Co Ltd
Pharmacopeia Drug Discovery Inc
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Daiichi Pharmaceutical Co Ltd
Pharmacopeia Inc
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Publication of CN1391473A publication Critical patent/CN1391473A/zh
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    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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CN00809510A 1999-06-30 2000-06-30 Vla－4抑制剂化合物 Pending CN1391473A (zh)

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JP7189369B2 (ja) 2018-10-30 2022-12-13 ギリアード サイエンシーズ， インコーポレイテッド アルファ４β７インテグリンの阻害のための化合物
CN112969687A (zh) 2018-10-30 2021-06-15 吉利德科学公司 作为α4β7整合素抑制剂的喹啉衍生物
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AU781438B2 (en) 2005-05-26

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