NO20016319L - VLA-4 inhibitor-forbindelser - Google Patents
VLA-4 inhibitor-forbindelserInfo
- Publication number
- NO20016319L NO20016319L NO20016319A NO20016319A NO20016319L NO 20016319 L NO20016319 L NO 20016319L NO 20016319 A NO20016319 A NO 20016319A NO 20016319 A NO20016319 A NO 20016319A NO 20016319 L NO20016319 L NO 20016319L
- Authority
- NO
- Norway
- Prior art keywords
- vla
- inhibitor compounds
- inhibitor
- compounds
- Prior art date
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14169299P | 1999-06-30 | 1999-06-30 | |
US14160299P | 1999-06-30 | 1999-06-30 | |
US14160199P | 1999-06-30 | 1999-06-30 | |
PCT/US2000/018079 WO2001000206A1 (en) | 1999-06-30 | 2000-06-30 | Vla-4 inhibitor compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20016319D0 NO20016319D0 (no) | 2001-12-21 |
NO20016319L true NO20016319L (no) | 2002-02-28 |
NO324892B1 NO324892B1 (no) | 2007-12-27 |
Family
ID=27385682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20016319A NO324892B1 (no) | 1999-06-30 | 2001-12-21 | VLA-4 inhibitor-forbindelser, deres anvendelse samt farmasoytisk preparat |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1189612A4 (no) |
JP (1) | JP2003503350A (no) |
CN (1) | CN1391473A (no) |
AR (1) | AR035011A1 (no) |
AU (1) | AU781438B2 (no) |
BR (1) | BR0012068A (no) |
CA (1) | CA2369308A1 (no) |
HK (1) | HK1043318A1 (no) |
IL (1) | IL146288A0 (no) |
MX (1) | MXPA01013406A (no) |
NO (1) | NO324892B1 (no) |
TW (1) | TWI283240B (no) |
WO (1) | WO2001000206A1 (no) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1324996A2 (de) * | 2000-01-17 | 2003-07-09 | Bayer CropScience AG | Substituierte arylketone |
DE10006453A1 (de) * | 2000-02-14 | 2001-08-16 | Bayer Ag | Piperidylcarbonsäuren als Integrinantagonisten |
AU2001268607A1 (en) | 2000-06-21 | 2002-01-02 | Bristol-Myers Squibb Company | Piperidine amides as modulators of chemokine receptor activity |
ATE524441T1 (de) | 2000-12-28 | 2011-09-15 | Daiichi Seiyaku Co | Vla-4-inhibitoren |
DE60235212D1 (de) | 2001-06-27 | 2010-03-11 | Smithkline Beecham Corp | Fluoropyrrolidine als Dipeptidylpeptidasehemmer |
GB0123765D0 (en) * | 2001-10-03 | 2001-11-21 | Bayer Ag | Para-amino benzoic acids |
US7956219B2 (en) * | 2002-05-09 | 2011-06-07 | Baker IDI Heart and Diabetes | Amino acid analogues |
PL215132B1 (pl) | 2002-06-27 | 2013-10-31 | Novo Nordisk As | Pochodna arylokarbonylowa jako srodek terapeutyczny, jej zastosowanie i kompozycja farmaceutyczna ja zawierajaca |
RU2340605C2 (ru) | 2002-06-27 | 2008-12-10 | Ново Нордиск А/С | Арилкарбонильные производные в качестве терапевтических средств |
JP4691988B2 (ja) * | 2002-10-03 | 2011-06-01 | 小野薬品工業株式会社 | Lpa受容体拮抗剤 |
GB0225944D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
WO2004099136A1 (ja) | 2003-05-09 | 2004-11-18 | Daiichi Pharmaceutical Co., Ltd. | ピロリジン誘導体の製造方法 |
US7691894B2 (en) | 2003-07-24 | 2010-04-06 | Daiichi Pharmaceutical Co., Ltd. | Cyclohexanecarboxylic acid compound |
JP4667384B2 (ja) * | 2003-10-07 | 2011-04-13 | レノビス, インコーポレイテッド | イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法 |
KR101126225B1 (ko) | 2004-01-06 | 2012-04-12 | 노보 노르디스크 에이/에스 | 헤테로아릴-유리아 및 글루코키나아제 활성제로서의 그들의 사용 |
JP2005350417A (ja) * | 2004-06-11 | 2005-12-22 | Dai Ichi Seiyaku Co Ltd | 還元的エーテル化法を用いたピロリジン誘導体の製造法 |
JP4649476B2 (ja) * | 2004-08-16 | 2011-03-09 | メルク・シャープ・エンド・ドーム・コーポレイション | Vla−4拮抗薬 |
JP5107724B2 (ja) | 2005-12-13 | 2012-12-26 | 第一三共株式会社 | Vla−4阻害薬 |
AR068875A1 (es) | 2007-10-16 | 2009-12-09 | Novartis Ag | Derivados de 4-5-dihidro-5-oxo-imidazol,composiciones farmaceuticas que los contienen, proceso de preparacion y uso de los mismos como inhibidores de receptores de npy y2 no peptidicos, para el tratamiento de trastornos de ansiedad , depresion, trastornos metabolicos y endocrinos. |
EP2628726A1 (en) * | 2008-03-26 | 2013-08-21 | Novartis AG | Hydroxamate-based inhibitors of deacetylases b |
US8735423B2 (en) * | 2009-11-18 | 2014-05-27 | Suven Life Sciences Limited | Bicyclic compounds as α4β2 nicotinic acetylcholine receptor ligands |
EP2694472B1 (en) * | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
CA3093025A1 (en) | 2018-06-12 | 2019-12-19 | Vtv Therapeutics Llc | Therapeutic uses of glucokinase activators in combination with insulin or insulin analogs |
CA3114240C (en) | 2018-10-30 | 2023-09-05 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
SG11202103484RA (en) | 2018-10-30 | 2021-05-28 | Gilead Sciences Inc | Quinoline derivatives as alpha4beta7 integrin inhibitors |
CN112969504B (zh) | 2018-10-30 | 2024-04-09 | 吉利德科学公司 | 用于抑制α4β7整合素的化合物 |
JP7189368B2 (ja) | 2018-10-30 | 2022-12-13 | ギリアード サイエンシーズ, インコーポレイテッド | アルファ4ベータ7インテグリンの阻害のための化合物 |
KR20210133984A (ko) | 2019-02-26 | 2021-11-08 | 바이엘 악티엔게젤샤프트 | 해충 방제제로서의 축합된 비시클릭 헤테로시클릭 유도체 |
CA3148613A1 (en) | 2019-08-14 | 2021-02-18 | Gilead Sciences, Inc. | Phenylalanine derived compounds and their use as inhinitors of alpha 4 beta 7 integrin |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
US6248713B1 (en) * | 1995-07-11 | 2001-06-19 | Biogen, Inc. | Cell adhesion inhibitors |
JP2002512625A (ja) * | 1997-05-29 | 2002-04-23 | メルク エンド カンパニー インコーポレーテッド | 細胞接着阻害薬としての複素環アミド化合物 |
WO1999020272A1 (en) * | 1997-10-21 | 1999-04-29 | Merck & Co., Inc. | Azapeptide acids as cell adhesion inhibitors |
IL135836A0 (en) * | 1997-10-31 | 2001-05-20 | Aventis Pharma Ltd | Substituted anilides |
AU3716499A (en) * | 1998-04-21 | 1999-11-08 | Aventis Pharma Limited | Substituted diamines and their use as cell adhesion inhibitors |
CN1308616A (zh) * | 1998-06-30 | 2001-08-15 | 辉瑞产品公司 | 用于治疗炎性、自身免疫和呼吸疾病的依赖于vla-4的细胞结合的非肽基抑制剂 |
-
2000
- 2000-06-30 IL IL14628800A patent/IL146288A0/xx not_active IP Right Cessation
- 2000-06-30 JP JP2001505915A patent/JP2003503350A/ja active Pending
- 2000-06-30 WO PCT/US2000/018079 patent/WO2001000206A1/en active IP Right Grant
- 2000-06-30 AU AU59031/00A patent/AU781438B2/en not_active Ceased
- 2000-06-30 BR BR0012068-5A patent/BR0012068A/pt not_active Application Discontinuation
- 2000-06-30 AR ARP000103363A patent/AR035011A1/es unknown
- 2000-06-30 CA CA002369308A patent/CA2369308A1/en not_active Abandoned
- 2000-06-30 TW TW089112968A patent/TWI283240B/zh not_active IP Right Cessation
- 2000-06-30 CN CN00809510A patent/CN1391473A/zh active Pending
- 2000-06-30 MX MXPA01013406A patent/MXPA01013406A/es active IP Right Grant
- 2000-06-30 EP EP00945035A patent/EP1189612A4/en not_active Withdrawn
-
2001
- 2001-12-21 NO NO20016319A patent/NO324892B1/no unknown
-
2002
- 2002-07-09 HK HK02105102.2A patent/HK1043318A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
AR035011A1 (es) | 2004-04-14 |
MXPA01013406A (es) | 2003-09-04 |
CN1391473A (zh) | 2003-01-15 |
AU781438B2 (en) | 2005-05-26 |
WO2001000206A1 (en) | 2001-01-04 |
AU5903100A (en) | 2001-01-31 |
EP1189612A4 (en) | 2005-02-16 |
NO324892B1 (no) | 2007-12-27 |
IL146288A0 (en) | 2002-07-25 |
EP1189612A1 (en) | 2002-03-27 |
NO20016319D0 (no) | 2001-12-21 |
TWI283240B (en) | 2007-07-01 |
HK1043318A1 (zh) | 2002-09-13 |
JP2003503350A (ja) | 2003-01-28 |
CA2369308A1 (en) | 2001-01-04 |
BR0012068A (pt) | 2002-05-14 |
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