CN1390143A - 两亲型前药 - Google Patents
两亲型前药 Download PDFInfo
- Publication number
- CN1390143A CN1390143A CN00815508A CN00815508A CN1390143A CN 1390143 A CN1390143 A CN 1390143A CN 00815508 A CN00815508 A CN 00815508A CN 00815508 A CN00815508 A CN 00815508A CN 1390143 A CN1390143 A CN 1390143A
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- Prior art keywords
- prodrug
- etoposide
- oligomer
- chemical compound
- peg
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Images
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
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- 2000-09-07 EP EP00964949A patent/EP1212099A2/en not_active Withdrawn
- 2000-09-07 CA CA002384645A patent/CA2384645A1/en not_active Abandoned
- 2000-09-07 PL PL00354261A patent/PL354261A1/xx not_active Application Discontinuation
- 2000-09-07 JP JP2001523037A patent/JP2003509385A/ja active Pending
- 2000-09-07 BR BR0013948-3A patent/BR0013948A/pt not_active IP Right Cessation
-
2002
- 2002-03-12 NO NO20021213A patent/NO20021213L/no not_active Application Discontinuation
-
2004
- 2004-03-24 US US10/808,044 patent/US7119074B2/en not_active Expired - Fee Related
- 2004-03-29 US US10/811,760 patent/US20040253206A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PL354261A1 (en) | 2003-12-29 |
KR20020059398A (ko) | 2002-07-12 |
US7119074B2 (en) | 2006-10-10 |
CZ2002928A3 (cs) | 2002-09-11 |
NO20021213L (no) | 2002-05-13 |
US20040180840A1 (en) | 2004-09-16 |
RU2002109595A (ru) | 2003-11-27 |
BR0013948A (pt) | 2002-05-14 |
AU7575600A (en) | 2001-04-17 |
HUP0204110A2 (hu) | 2003-04-28 |
CA2384645A1 (en) | 2001-03-22 |
WO2001019406A3 (en) | 2002-01-17 |
JP2003509385A (ja) | 2003-03-11 |
HUP0204110A3 (en) | 2003-08-28 |
MXPA02002712A (es) | 2003-10-14 |
NO20021213D0 (no) | 2002-03-12 |
US6713454B1 (en) | 2004-03-30 |
WO2001019406A2 (en) | 2001-03-22 |
EP1212099A2 (en) | 2002-06-12 |
IL148558A0 (en) | 2002-09-12 |
US20040253206A1 (en) | 2004-12-16 |
NZ517681A (en) | 2004-01-30 |
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