CN1353706A - 整合素受体配体 - Google Patents

整合素受体配体 Download PDF

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CN1353706A
CN1353706A CN00807554A CN00807554A CN1353706A CN 1353706 A CN1353706 A CN 1353706A CN 00807554 A CN00807554 A CN 00807554A CN 00807554 A CN00807554 A CN 00807554A CN 1353706 A CN1353706 A CN 1353706A
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J-C·捷奇尔
A·克林
H·杰内斯特
U·兰奇
A·劳特巴赫
C·I·格雷夫
T·萨布考斯基
J·萨德斯基
W·霍恩伯格
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Priority claimed from DE1999162998 external-priority patent/DE19962998A1/de
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Abstract

本发明涉及一种能够与整合素受体结合的新化合物、它的制备、它们作为整合素受体配体的用途以及用于治疗疾病、含有这些化合物的药物制剂、以及含有至少一种其他活性化合物的药物制剂。

Description

整合素受体配体
本发明涉及一种能够与整合素受体结合的新化合物,以及它们的制备和用途。
整合素是一种细胞表面的糖蛋白受体,它能够调节相同或不同类型细胞之间以及细胞和细胞外基质蛋白之间的相互作用。在生理学过程,例如胚胎发生、止血、伤口愈合、免疫应答和组织构造的形成/维护中都会涉及到它们。
细胞粘附分子基因的表达紊乱和受体功能的失调可能会成为大量疾病发病机理的原因之一,这些疾病如肿瘤、血栓栓塞现象、心血管疾病、肺部疾病、ZNS、肾、胃肠道疾病或炎症。
整合素是分别由α和β跨膜亚单元组成的异源二聚体,所述亚单元可以是非共价性连接的。迄今为止,已经鉴别了16种不同的α和8种不同β亚单元和22种不同的组合。
整合素αvβ3,也被称为玻连蛋白受体,能够调节与大量配体—血浆蛋白、细胞外基质蛋白、细胞表面蛋白的粘合,配体中的大多数都含有氨基酸序列RGD(Cell,1986,44,517-518;Science 1987,238,491-497),例如玻连蛋白、纤维蛋白原、纤连蛋白、维勒布兰德氏因子、血小板反应蛋白、骨桥蛋白、层粘连蛋白、胶原、凝血酶、腱生蛋白、MMP-2、骨唾液蛋白II、各种病毒、真菌、寄生虫的和细菌蛋白、天然的整合素拮抗体例如解整合蛋白、神经毒素-Mambin-和水蛭蛋白-Decorsin,Ornatin-和一些非-RGD配体,例如Cyr-61和PECAM-1(L. Piali,J. Cell Biol. 1995,130,451-460;Buckley,J. CellScience 1996,109,437-445,J. Biol. Chem. 1998,273,3090-3096)。
好几种整合素受体显示出与含有RGD基序配体的交叉活性。这样,整合素αIIbβ3,也被称为血小板纤维蛋白原受体、识别纤连蛋白、玻连蛋白、血小板反应蛋白、维勒布兰德氏因子和纤维蛋白原。
尤其在内皮细胞、血小板、单核细胞/巨噬细胞、平滑肌细胞、一些B细胞、成纤维细胞、破骨细胞和各种肿瘤细胞例如黑瘤、成胶质细胞瘤、肺、乳腺、前列腺和膀胱癌、骨肉瘤或成神经细胞瘤上表达整合素αvβ3
在各种病理状态下例如前血栓形成状态,血管损伤情形、肿瘤生长或转移或再灌注,和在活性细胞上,特别在内皮细胞、平滑肌细胞或巨噬细胞上能够观察到表达的增加。
尤其在下列病理状态下已经测出整合素αvβ3的参与:
心血管疾病例如动脉粥样硬化、血管损伤后的再狭窄和血管成形术(新内膜形成,平滑肌细胞移植和增生)(J. Vasc. Surg. 1994,19,125-134;Circulation 1994,90,2203-2206),
急性肾衰(Kidney Int. 1994,46,1050-1058;Proc. Natl. Acad.Sci. 1993,90,5700-5704;Kidney Int. 1995,48,1375-1385),
与血管生成有关的微血管病,例如糖尿病性视网膜病或类风湿性关节炎(Ann. Rev. Physiol 1987,49,453-464;Int. Ophthalmol.1987,11,41-50;Cell 1994,79,1157-1164;J. Biol. Chem.1992,267,10931-10934),
动脉血栓形成,
中风(Phase II Studien mit ReoPro,Centocor Inc.,欧洲中风会议第8次年刊),
癌,例如肿瘤转移或肿瘤生长(肿瘤诱导的血管生成)(Cell 1991,64,327-336;Nature 1989,339,58-61;Science 1995,270,1500-1502),
骨质疏松症(破骨细胞的增生、趋化性和附着后对骨基质的骨吸收)(FASEB J. 1993,7,1475-1482;Exp. Cell Res. 1991,195,368-375,Cell 1991,64,327-336),
高血压(Am. J. Physiol. 1998,275,H1449-H1454),牛皮癣(Am.J. Pathol. 1995,147,1661-1667),
甲状旁腺机能亢进,
佩吉特疾病(J. Clin. Endocrinol. Metab. 1996,81,1810-1820),
恶性高钙血症(Cancer Res. 1998,58,1930-1935),
转移性的溶骨损害(Am. J. Pathol. 1997,150,1383-1393),
病原体蛋白(例如HIV-1毒素抗毒素(tat))诱导的过程(例如血管生成,卡波氏肉瘤)(Blood 1999,94,663-672),
炎症(J. Allergy Clin. Immunol. 1998,102,376-381),
心力衰竭、CHF和用于抗病毒、杀寄生虫、抗真菌或抗细菌治疗和预防(粘连和内化)(J. Infect. Dis. 1999,180,156-166;J.Virology 1995,69,2664-2666;Cell 1993,73,309-319)。
由于其关键的作用,含有低分子量的整合素αvβ3配体的药物制剂具有重大的治疗和诊断价值并且尤其是用于所提到的适应征。
有益的αvβ3整合素受体配体能够以增加了的亲合力与整合素αvβ3受体结合。
特别有益的αvβ3整合素受体配体另外也对整合素αvβ3具有增高的选择性,并且对整合素αIIbβ3的作用降低至少10倍,优选至少100倍。
大量的化合物例如抗αvβ3-单克隆抗体、含有RGD结合序列的肽、天然的含RGD的蛋白(例如解整合素)和低分子量化合物,已经显示了整合素αvβ3拮抗作用,并且已经证实了体内的有益作用(FEBS Letts1991,291,50-54;J. Biol. Chem. 1990,265,12267-12271;J. Biol.Chem. 1994,269,20233-20238;J. Cell Biol 1993,51,206-218;J.Biol. Chem. 1987,262,17703-17711;Bioorg. Med. Chem.1998,6,1185-1208)。
WO 99/30713公开了1,3-取代的四氢嘧啶-2(1H)-酮衍生物和哌啶-2-酮衍生物,WO 99/31099公开了1,3-取代的咪唑啉-2-酮衍生物,WO 98/35949公开了2,6-取代的2H-1,4-苯并噁嗪-3(4H)-酮衍生物,WO 9800395和WO 9723451公开了O-取代的酪氨酸衍生物,EP 710657和EP 741133公开了3,5-取代的1,3-噁唑烷-2-酮,以及WO 97/37655公开了作为αvβ3整合素受体的拮抗剂的异吲哚。
本发明的一个目的是提供一种新的具有有益性能的整合素受体配体。我们已经发现通过化学式I的化合物可以实现这种目的:
               B-G-L                I其中B、G和L具有下列含义:L是化学式IL的结构单元
              -U-T                  IL其中T是COOH基或者可水解成COOH的基团,并且-U-是-(CRL 1RL 2)a-(VL)b-(CRL 3RL 4)c-(WL)d-(CRL 5RL 6)e-(XL)f-(CRL 7RL 8)g-其中a,c,e,g分别是0,1,2,或3,b,d,f分别是0或1,RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7,RL 8分别是氢原子,卤素,羟基,支链或直链的、可以被取代或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基或者C1-C6-亚烷基-C3-C7-环烷基,-(CH2)w-(YL)y-RL 9基,可以被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基或者,在每种相互独立的情况中,两个基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8一起是3-至7-元、被取代的或不被取代的、饱和或不饱和的碳环或杂环,该杂环可含有选自O、N和S组中的至多三个杂原子,w是0、1、2、3或4,y是0或1YL是-CO-,-CO-N(RY 1)-,-N(RY 1)-CO-,-N(RY 1)-CO-N(RY 1*)-,-N(RY 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RY 1)-,-SO2-O-,-CO-O-,-O-CO-,-O-CO-N(Ry 1)-,-N(RY 1)-或-N(RY 1)-SO2-,
RY 1,RY 1*
分别是氢,支链或直链的、被取代或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,芳基,芳烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-或SO2-亚烷基-芳基,
RL 9是氢,或者羟基,CN,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基,被取代或不被取代的C3-C7-环烷基-,芳基-,杂芳基或芳烷基,不被取代或被C1-C4-烷基或芳基取代的C2-C6-炔基或C2-C6-烯基,被取代或不被取代C6-C12-二环烷基,C1-C6-亚烷基-C6-C12-双环烷基-,C7-C20-三环烷基-,或C1-C6-亚烷基-C7-C20-三环烷基,或3-至8-元、饱和或不饱和杂环并且该杂环由至多3个相同或不同基团取代并含有至多三个不同或相同的选自O、N、S的杂原子,其中两个基团可能一起形成稠合的,饱和的、不饱和的或芳香碳环或杂环,该杂环可含有至多3个不同或相同的选自O、N、S的杂原子,并且该环可能被取代或不被取代,或者另一被取代或不被取代的、饱和的、不饱和的或芳香环可稠合到该环上,或者RL 9基与RY 1或RY 1*形成饱和或不饱和的C3-C7-杂环,该杂环还可以含有至多两个另外的选自O、S或N的杂原子,
WL是被取代的或不被取代的4-至11-元单环或多环脂族烃或芳香烃,它含有至多6个双键和至多6个选自于N、O、S中的杂原子,
VL,XL
分别是                  -CO-,-CO-NRL 10-,-NRL 10-CO-,
-S-,-SO-,-SO2-,-SO2-NRL 10-,-NRL 10-SO2-,-CS-,
-CS-NRL 10-,-NRL 10-CS-,-CS-O-,-O-CS-,-CO-O-,
-O-CO-,-O-,亚乙炔基,-CHRL 11-O-CHRL 12-,
-C(=CRL 11RL 12)-,-CRL 11=CRL 12-,-CRL 11(ORL 13)-CHRL12-,
-CHRL 11-CRL 12(ORL 13)-,-CH(NRL 14-SO2-RL 15)-,
-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,
CH(NRL 14-CO-NRL 14′RL 15)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-
或CH(CO-NRL 14RL 15)-,
RL 10是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基-,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基,CO-O-亚烷基-芳基-,CO-亚烷基-芳基,芳烷基-,CO-芳基-,SO2-芳基-,杂芳基-,CO-杂芳基-,杂芳基烷基-或SO2-亚烷基-芳基,或者RL 10和选自于RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8中的一个基团一起可以是含有至多5个相同或不同的O、N或S杂原子的被取代的或不被取代的4-至8-元杂环,
RL 11,RL 12
分别是氢,羟基,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C4-烷氧基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或者被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 13是氢、支链或直链、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 14,RL 14’
分别是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧烷基-,C2-C6-烯基,C3-C12-炔基,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,C1-C6-亚烷基-C3-C7-环烷基,或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-,杂芳基烷基-,芳烷基或SO2-亚烷基芳基,
RL 15是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基-,C1-C6-亚烷基-C3-C7-环烷基,C6-C12-双环烷基-,C1-C6-亚烷基-C6-C12-双环烷基-,-C7-C20-三环烷基-或C1-C6-亚烷基-C7-C20-三环烷基,由至多3个相同或不同基团取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基烷基或3-至8-元、饱和、不饱和或芳香杂环基,该杂环可含有至多三个不同或相同的O、N、S的杂原子,其中两个基团一起可能是稠合的、饱和、不饱和或芳香碳环或杂环,该杂环可含有至多3个不同或相同的O、N、S杂原子,而且该环可能被取代或不被取代,或者另一个被取代的或不被取代的饱和、不饱和或芳香环可稠合到该环上,或者RL 15基与RL 14或RL 14*形成饱和或不饱和的任选含有至多两个另外的选自O、S或N中的杂原子的C3-C7-杂环,和
RL 16是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基,
G是具有化学式IG的结构单元
Figure A0080755400351
其中,结构单元G可在两个取向构建入,和
ZG是氧、硫或NRG 3
RG 1,RG 2
分别是氢,CN,NO2,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基或C2-C6-炔基,支链或直链、被取代的或不被取代的C1-C4-亚烷基-ORG 4,C1-C4-亚烷基-CO-ORG 4,C1-C4-亚烷基-CO-RG 4,C1-C4-亚烷基-SO2-NRG 5RG 6,C1-C4-亚烷基-CO-NRG 5RG 6,C1-C4-亚烷基-NRG 5RG 6或C1-C4-亚烷基-SRG 4,被取代的或不被取代的C3-C7-环烷基,C3-C7-杂环烷基,C3-C7-杂环烯基,C1-C4-亚烷基-C3-C7-环烷基,C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,被取代的或不被取代的芳基,芳烷基,杂芳基或杂芳烷基,-S-RG 4,-O-RG 4,-SO-RG 4,-SO2-RG 4,-CO-ORG 4,-O-CO-RG 4,-O-CO-NRG 5RG 6,-SO2-NRG 5RG 6,-CO-NRG 5RG 6,-NRG 5RG 6,CO-RG 4,或RG 1和RG 2一起是被取代的或不被取代的、饱和的、不饱和的或芳香的3-至9-元碳环、多碳环、含有至多4个选自O、N、S的杂原子的杂环或杂多环。
RG 3是氢,羟基,CN,支链或直链的、被取代的或不被取代的C1-C6-烷基或C1-C4-烷氧基或被取代的或不被取代的C3-C7-环烷基-,-O-C3-C7-环烷基,芳基-,-O-芳基,芳烷基或-O-亚烷基-芳基。
RG 4是氢,支链或直链被取代的或不被取代的C1-C8-烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基-,单-和双-烷基氨基亚烷基-或酰基氨基亚烷基或被取代的或不被取代的芳基,杂环烷基-,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基-,C1-C4-亚烷基-杂环烯基或杂芳基烷基,
RG 5,RG 6
分别是氢,支链或直链被取代的或不被取代的C1-C8烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基,单-和双烷基氨基亚烷基或酰基氨基亚烷基,被取代的或不被取代的芳基,杂环烷基,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基,C1-C4-亚烷基-杂环烯基-或杂芳烷基,或-SO2-RG 4,-CO-ORG 4,-CO-NRG 4RG 4*或-CO-RG 4,和
RG 4*是不同于RG 4的RG 4基,
B是含有至少一个原子的结构单元,这个原子在生理学条件下作为氢受体可形成氢键,其中至少一个氢受体原子沿结构单元骨架沿最短的可能途径与结构单元G之间具有4至13原子键的间隔,
和生理学上可接受的盐、前体药物和对映体纯的或非对映体纯的和互变异构的形式。
除非另外说明,对于本发明中的所有基团或取代基卤素基团是指如F、Cl、Br或I。
被取代的或不被取代的基团是指相应的未取代和取代过的基团。对于本发明内的所有被取代的基团来说,如果没有详细说明取代基,那么相互独立地有至多5个取代基,例如选自下列基团:
-NO2,-NH2,-OH,-CN,-COOH,-O-CH2-COOH,卤素,支链或直链被取代的或不被取代的C1-C4-烷基,例如甲基,CF3,C2F5或CH2F,支链或直链、被取代的或不被取代的-CO-O-C1-C4-烷基,C3-C7-环烷基,C1-C4-烷氧基,C1-C4-烷硫基,-NH-CO-O-C1-C4-烷基,-O-CH2-COO-C1-C4-烷基,-NH-CO-C1-C4-烷基,-CO-NH-C1-C4-烷基,-NH-SO2-C1-C4-烷基,-SO2-NH-C1-C4-烷基,-N(C1-C4-烷基)2,-NH-C1-C4-烷基,或-SO2-C1-C4-烷基,例如-SO2-CF3,被取代的或不被取代的-NH-CO-芳基,-CO-NH-芳基,-NH-CO-O-芳基,-NH-CO-O-亚烷基-芳基,-NH-SO2-芳基,-SO2-NH-芳基,-CO-NH-苄基,-NH-SO2-苄基或-SO2-NH-苄基,被取代的或不被取代的-SO2-NR4R5或-CO-NR4R5基,R4和R5可相互独立地具有如本文以后的RL 14的含义,或者R4和R5两个基团共同为3-至6-元的被取代的或不被取代的饱和、非饱和或芳香杂环,该杂环除了环氮原子之外,还可以含最多3个其它的不同的或相同的O、N、S杂原子,并且任选在该杂环上取代的两个基团一起是稠合的、饱和、不饱和或芳香碳环或杂环,该杂环可含有至多3个不同或相同的O、N、S杂原子,并且该环可能被取代或不被取代,或另一被取代的或不被取代的环可稠合到该环上。
对本发明的所有末端键合的、取代的杂芳基和杂芳烷基来说,除了前述列出的取代基外,杂芳基部分的两个取代基可形成稠合的5-至7-元、不饱和的或芳香碳环。
结构单元L中的T是指COOH基或能够水解成COOH的基团。能够水解成COOH的基团是指在水解后转化成COOH基的基团。
所提到的作为能够水解成COOH的基团T的例子是下式基团
其中R1具有以下含义:
a)OM,其中M是金属阳离子,例如碱金属阳离子如锂、钠、钾,当量的碱土金属阳离子如钙、镁和钡,或者环境上相容的有机铵离子如伯、仲、叔或季C1-C4-烷基铵或铵离子,例如ONa,OK或OLi,
b)支链或直链的、被卤素取代的或不被取代的C1-C8-烷氧基,例如甲氧基,乙氧基,丙氧基,1-甲基乙氧基,丁氧基,1-甲基-丙氧基,2-甲基丙氧基,1,1-二甲基乙氧基,尤其是甲氧基,乙氧基,1-甲基乙氧基,戊氧基,己氧基,庚氧基,辛氧基,二氟甲氧基,三氟甲氧基,氯代二氟甲氧基,1-氟乙氧基,2-氟乙氧基,2,2-二氟乙氧基,1,1,2,2-四氟乙氧基,2,2,2-三氟乙氧基,2-氯-1,1,2-三氟乙氧基或五氟乙氧基
c)支链或直链的、被卤素取代的或不被取代的C1-C4-烷基硫基例如甲硫基,乙硫基,丙硫基,1-甲基乙硫基,丁硫基,1-甲基丙硫基,2-甲基丙硫基或1,1-二甲基乙硫基
d)被取代的或不被取代的-O-亚烷基-芳基,例如-O-苄基
e)R1此处为-(O)ml-N(R2)(R3),其中ml是0或1,R2和R3可以相同或也可以不同,具有以下含义:
氢,
支链或直链的、被取代的或不被取代的
C1-C6-烷基,例如,甲基,乙基,丙基,1-甲基乙基,丁基,1-甲基丙基,2-甲基丙基,1,1-二甲基乙基,戊基,1-甲基丁基,2-甲基丁基,1,2-二甲基丙基,1,1-二甲基丙基,2,2-二甲基丙基,1-乙基丙基,己基,1-甲基戊基,1,2-二甲基丁基,1,3-二甲基丁基,2,3-二甲基丁基,1,1-二甲基丁基,2,2-二甲基丁基,3,3-二甲基丁基,1,1,2-三甲丙基,1,2,2-三甲基丙基,1-乙基丁基,2-乙基丁基或1-乙基-2-甲基丙基或相应的被取代的基团,优选甲基,乙基,丙基,丁基或异丁基,
C2-C6-烯基,例如乙烯基,2-丙烯基,2-丁烯基,3-丁烯基,1-甲基-2-丙烯基,2-甲基-2丙烯基,2-戊烯基,3-戊烯基,4-戊烯基,1-甲基-2-丁烯基,2-甲基-2-丁烯基,3-甲基-2-丁烯基,1-甲基-3-丁烯基,2-甲基-3-丁烯基,3-甲基-3-丁烯基,1,1-二甲基-2-丙烯基,1,2-二甲基-2-丙烯基,1-乙基-2-丙烯基,2-己烯基,3-己烯基,4-己烯基,5-己烯基,1-甲基-2-戊烯基,2-甲基-2-戊烯基,3-甲基-2-戊烯基,4-甲基-2-戊烯基,3-甲基-3-戊烯基,4-甲基3-戊烯基,1-甲基-4-戊烯基,2-甲基-4-戊烯基,3-甲基-4-戊烯基,4-甲基-4-戊烯基,1,1-二甲基-2-丁烯基,1,1-二甲基-3-丁烯基,1,2-二甲基-2-丁烯基,1,2-二甲基-3-丁烯基,1,3-二甲基-2-丁烯基,1,3-二甲基-3-丁烯基,2,2-二甲基-3-丁烯基,2,3-二甲基-2-丁烯基,2,3-二甲基-3-丁烯基,1-乙基-2-丁烯基,1-乙基-3-丁烯基,2-乙基-2-丁烯基,2-乙基-3-丁烯基,1,1,2-三甲基-2-丙烯基,1-乙基-1-甲基-2-丙烯基和1-乙基-2-甲基-2-丙烯基,尤其2-丙烯基,2-丁烯基,3-甲基-2-丁烯基或3-甲基-2-戊烯基或相应的被取代的基团,
C2-C6-炔基,例如乙炔基,2-丙炔基,2-丁炔基,3-丁炔基,1-甲基-2-丙炔基,2-戊炔基,3-戊炔基,4-戊炔基,1-甲基-3-丁炔基,2-甲基-3-丁炔基,1-甲基-2-丁炔基,1,1-二甲基-2-丙炔基,1-乙基-2-丙炔基,2-己炔基,3-己炔基,4-己炔基,5-己炔基,1-甲基-2-戊炔基,1-甲基-2-戊炔基,1-甲基-3-戊炔基,1-甲基-4-戊炔基,2-甲基-3-戊炔基,2-甲基-4-戊炔基,3-甲基-4-戊炔基,4-甲基-2-戊炔基,1,1-二甲基-2-丁炔基,1,1-二甲基-3-丁炔基,1,2-二甲基-3-丁炔基,2,2-二甲基-3-丁炔基,1-乙基-2-丁炔基,1-乙基-3-丁炔基,2-乙基-3-丁炔基和1-乙基-1-甲基-2-丙炔基,优选2-丙炔基,2-丁炔基,1-甲基-2-丙炔基或1-甲基-2-丁炔基,或相应的取代的基团,
C3-C8-环烷基,例如环丙基,环丁基,环戊基,环己基和环庚基,环辛基或相应的被取代的基团,
或苯基,可以由以下基团取代一或多次,例如取代一至三次:卤素,硝基,氰基,C1-C4-烷基,C1-C4-卤代烷基,C1-C4-烷氧基,C1-C4-卤代烷氧基或C1-C4-烷基硫基,例如2-氟苯基,3-氯苯基,4-溴苯基,2-甲基苯基,3-硝基苯基,4-氰基苯基,2-三氟甲基苯基,3-甲氧基苯基,4-三氟乙氧基苯基,2-甲硫基苯基,2,4-二氯苯基,2-甲氧基-3-甲基苯基,2,4-二甲氧基苯基,2-硝基-5-氰基苯基,2,6-二氟苯基,
或者R2和R3共同形成的C4-C7-亚烷基链,它是闭环的、可被例如C1-C4-烷基取代或不被取代并且可含有选自氧、硫或氮的杂原子,例如-(CH2)4-,-(CH2)5-,-(CH2)6-,-(CH2)7-,-(CH2)2-O-(CH2)2-,-CH2-S-(CH2)3-,-(CH2)2-O-(CH2)3-,-NH-(CH2)3-,-CH2-NH-(CH2)2-,-CH2-CH=CH-CH2-,-CH=CH-(CH2)3-,-CO-(CH2)2-CO-或-CO-(CH2)3-CO-。
优选的T基团是-COOH,-CO-O-C1-C8-烷基或-CO-O-苄基。
结构单元-U-中的系数a,c,e和g相互独立地是0,1,2或3,优选0,1或2。
而且,优选结构单元-U-的a,c,e和g的系数总和小于7。
尤其优选结构单元-U-中,a,c,e和g相互独立地是0或1。
对于RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,优选的卤原子是氟。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,支链或直链C1-C6-烷基分别是甲基,乙基,丙基,1-甲基乙基,丁基,1-甲基丙基,2-甲基丙基,1,1-二甲基乙基,戊基,1-甲基丁基,2-甲基丁基,1,2-二甲基丙基,1,1-二甲基-丙基,2,2-二甲基丙基,1-乙基丙基,己基,1-甲基戊基,1,2-二甲基丁基,1,3-二甲基丁基,2,3-二甲基丁基,1,1-二甲基丁基,2,2-二甲基丁基,3,3-二甲基丁基,1,1,2-三甲基丙基,1,2,2-三甲基丙基,1-乙基丁基,2-乙基丁基或1-乙基-2-甲基丙基,优选支链或直链C1-C4-烷基,例如甲基,乙基,丙基,1-甲基乙基,丁基,1-甲基丙基,2-甲基丙基或1,1-二甲基乙基,尤其优选甲基。
对于结构单元L中的RL 1,RL 2,RL 3  RL 4,RL 5,RL 6,RL 7或RL 8来说,支链或直链C2-C6-烯基分别是例如乙烯基,2-丙烯基,2-丁烯基,3-丁烯基,1-甲基-2-丙烯基,2-甲基-2-丙烯基,2-戊烯基,3-戊烯基,4-戊烯基,1-甲基-2-丁烯基,2-甲基-2-丁烯基,3-甲基-2-丁烯基,1-甲基-3-丁烯基,2-甲基-3-丁烯基,3-甲基-3-丁烯基,1,1-二甲基-2-丙烯基,1,2-二甲基-2-丙烯基,1-乙基-2-丙烯基,2-己烯基,3-己烯基,4-己烯基,5-己烯基,1-甲基-2-戊烯基,2-甲基-2-戊烯基,3-甲基-2-戊烯基,4-甲基-2-戊烯基,3-甲基-3-戊烯基,4-甲基-3-戊烯基,1-甲基-4-戊烯基,2-甲基-4-戊烯基,3-甲基-4-戊烯基,4-甲基-4-戊烯基,1,1-二甲基-2-丁烯基,1,1-二甲基-3-丁烯基,1,2-二甲基-2-丁烯基,1,2-二甲基-3-丁烯基,1,3-二甲基-2-丁烯基,1,3-二甲基-3-丁烯基,2,2-二甲基-3-丁烯基,2,3-二甲基-2-丁烯基,2,3-二甲基-3-丁烯基,1-乙基-2-丁烯基,1-乙基-3-丁烯基,2-乙基-2-丁烯基,2-乙基-3-丁烯基,1,1,2-三甲基-2-丙烯基,1-乙基-1-甲基-2-丙烯基或1-乙基-2-甲基-2-丙烯基。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,支链或直链C2-C6-炔基分别是指,例如乙炔基,2-丙炔基,2-丁炔基,3-丁炔基,1-甲基-2-丙炔基,2-戊炔基,3-戊炔基,4-戊炔基,1-甲基-3-丁炔基,2-甲基-3-丁炔基,1-甲基-2-丁炔基,1,1-二甲基-2-丙炔基,1-乙基-2-丙炔基,2-己炔基,3-己炔基,4-己炔基,5-己炔基,1-甲基-2-戊炔基,1-甲基-2-戊炔基,1-甲基-3-戊炔基,1-甲基-4-戊炔基,2-甲基-3-戊炔基,2-甲基-4-戊炔基,3-甲基-4-戊炔基,4-甲基-2-戊炔基,1,1-二甲基-2-丁炔基,1,1-二甲基-3-丁炔基,1,2-二甲基-3-丁炔基,2,2-二甲基-3-丁炔基,1-乙基-2-丁炔基,1-乙基-3-丁炔基,2-乙基-3-丁炔基和1-乙基-1-甲基-2-丙炔基,优选乙炔基,2-丙炔基,2-丁炔基,1-甲基-2-丙炔基或1-甲基-2-丁炔基,尤其优选乙炔基。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,C3-C7-环烷基分别是指,例如环丙基,环丁基,环戊基,环己基或环庚基。
支链或直链C1-C6-亚烷基-C3-C7-环烷基,例如由支链或直链C1-C6-亚烷基和前述的C3-C7-环烷基组成。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,优选的被取代的或不被取代的芳基分别是被取代的或不被取代的苯基,1-萘基,或2-萘基。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,优选的被取代的或不被取代的芳烷基分别是被取代的或不被取代的苄基或苯乙基。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,杂芳基分别是指,例如2-吡啶基,3-吡啶基,4-吡啶基,2-呋喃基,3-呋喃基,2-吡咯基,3-吡咯基,2-噻吩基,3-噻吩基,2-噻唑基,4-噻唑基,5-噻唑基,2-噁唑基,4-噁唑基,5-噁唑基,2-嘧啶基,4-嘧啶基,5-嘧啶基,6-嘧啶基,3-吡唑基,4-吡唑基,5-吡唑基,3-异噻唑基,4-异噻唑基,5-异噻唑基,2-咪唑基,4-咪唑基,5-咪唑基,3-哒嗪基,4-哒嗪基,5-哒嗪基,6-哒嗪基,3-异噁唑基,4-异噁唑基,5-异噁唑基,噻二唑基,噁二唑基或三嗪基。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,取代的杂芳基,如上一般性对末端取代的杂芳基所述的那样,还指上述杂芳基的稠合衍生物,例如吲唑,吲哚,苯并噻吩,苯并呋喃,二氢吲哚,苯并咪唑,苯并噻唑,苯并噁唑,喹啉,2,3-二氢-1-苯并呋喃,喃喃并[2,3]吡啶,呋喃并[3,2]吡啶或异喹啉。
对于结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说,杂芳基烷基是指,例如由C1-C6-亚烷基和如上所述的杂芳基组成的基团,例如-CH2-2-吡啶基,-CH2-3-吡啶基,-CH2-4-吡啶基,-CH2-2-噻吩基,-CH2-3-噻吩基,-CH2-2-噻唑基,-CH2-4-噻唑基,CH2-5-噻唑基,-CH2-CH2-2-吡啶基,-CH2-CH2-3-吡啶基,-CH2-CH2-4-吡啶基,-CH2-CH2-2-噻吩基,-CH2-CH2-3-噻吩基,-CH2-CH2-2-噻唑基,-CH2-CH2-4-噻唑基,或-CH2-CH2-5-噻唑基。
对于两个基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8来说,可在各种情况下彼此独立地共同形成3-至7-元、被取代的或不被取代的、饱和或非饱和的碳环或杂环,该杂环可含有选自O、N或S组的至多三个杂原子。
-(CH2)w-(YL)y-RL 9由C0-C4-亚烷基、任选连接单元YL和RL 9组成,YL选自-CO-,-CO-N(RY 1)-,-N(RY 1)-CO-,-N(RY 1)-CO-N(Ry 1*)-,-N(RY 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RY 1)-,-SO2-O-,-CO-O-,-O-CO-,-O-CO-N(Ry 1)-,-N(RY 1)-或-N(RY 1)-SO2-,其中
RY 1,RY 1*
分别是氢,支链或直链的、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,芳基,芳烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-或SO2-亚烷基-芳基,优选氢原子,甲基,环丙基,烯丙基或炔丙基,特别优选氢原子或甲基,和
RL 9是氢,羟基,CN,卤素,支链或直链、被取代的或不被取代的C1-C6-烷基,被取代的或不被取代的C3-C7-环烷基,芳基,杂芳基或芳烷基,被C1-C4-烷基或芳基取代或不被取代的C2-C6-炔基成C2-C6-烯基,被取代的或不被取代的C6-C12-双环烷基,C1-C6-亚烷基-C6-C12-双环烷基-,C7-C20-三环烷基或C1-C6-亚烷基-C7-C20-三环烷基,或3-至8-元、饱和或不饱和杂环,该杂环由至多3个相同或不同的基团取代并含有至多三个不同或相同的O、N、S杂原子,在此两个基团可能形成稠合的、饱和的、不饱和的或芳香的碳环或可以含有至多3个不同或相同的O,N,S杂原子的杂环,该环被取代的或不被取代都是可能的,或另一被取代的或不被取代的,饱和、不饱和或芳香环可稠合到该环上,例如,被取代的或不被取代的2-吡啶基,3-吡啶基,4-吡啶基,2-呋喃基,3-呋喃基,2-吡咯基,3-吡咯基,2-噻吩基,3-噻吩基,2-噻唑基,4-噻唑基,5-噻唑基,2-噁唑基,4-噁唑基,5-噁唑基,2-嘧啶基,4-嘧啶基,5-嘧啶基,6-嘧啶基,3-吡唑基,4-吡唑基,5-吡唑基,3-异噻唑基,4-异噻唑基,5-异噻唑基,2-咪唑基,4-咪唑基,5-咪唑基,3-哒嗪基,4-哒嗪基,5-哒嗪基,6-哒嗪基,2-(1,3,4-噻二唑基),2-(1,3,4)-噁二唑基,3-异噁唑基,4-异噁唑基,5-异噁唑基或三嗪基。
RL 9和Ry 1或Ry 1*也可能共同形成饱和或不饱和C3-C7-杂环,该杂环可以不含或含有至多两个另外的选自O、S或N的不同杂原子。
RL 9和Ry 1或Ry 1*优选共同形成环胺作为C3-C7-杂环,这时,基团与同一氮原子连接,例如N-吡咯烷基,N-哌啶基,N-六氢氮杂基,N-吗啉基或N-哌嗪基,对于具有游离胺质子的杂环,例如N-哌嗪基,游离胺质子可以通过常规的胺保护基替换,这些保护基例如是甲基,苄基,Boc(叔-丁氧基-羰基),Z(苄氧基羰基),甲苯磺酰基,-SO2-C1-C4-烷基,-SO2-苯基或-SO2-苄基。
对于结构单元L的RL 1,RL 3,RL 5或RL 7来说,优选的-(CH2)w-(YL)y-RL 9基是被取代的或不被取代的天然氨基酸侧链,优选被取代的或不被取代的Ser,Thr,Tyr,Asp,Asn,Glu,Gln,Cys,Met,Lys或Orn氨基酸侧链,如Bachem公司1999,Novabiochem 1999,Neosystem1997/98和Advanced ChemTech 1999的商品目录介绍的非天然氨基酸侧链,它是被取代或不被取代的。
天然α-氨基酸的侧链是指含有β碳原子的侧链。非天然氨基酸的例子是β-氨基酸。在这种情形下,侧链是指含有γ碳原子的侧链。取代的侧链也是指,例如,在侧链的例如-NH2,-SH,-OH或-COOH的官能团上具有保护基团的侧链。
对结构单元L中的RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8来说特别优选的基团,每种情况下相互独立地,基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8之一是氢或甲基。
在结构单元-U-另一优选的实施方案中,基团RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8相互独立地是氢或甲基,条件是VL或XL相互独立地是基团-CH(NRL 14-SO2-RL 15)-,-CH(NRL 14-CO-RL 16)-,-CH(NRL 14-CO-ORL 16)-,-CH(NRL 14-CO-NRL 14’RL 15)-,-CH(CO-ORL 16)-或-CH(CO-NRL 14RL 15)-。
对于WL来说,含有至多6个双键和至多6个选自N、O、S杂原子的被取代的或不被取代的4-至11-元单-或多环脂肪或芳香烃优选为被取代的或不被取代的亚芳基,例如被取代的或不被取代的亚苯基或亚萘基,被取代的或不被取代的亚杂芳基,例如基团
Figure A0080755400441
和它们的取代或稠合衍生物,或者结构式IWL至IIIWL的基团,
其中的基团可以在两个取向构建入,系数r是0,1,2或3,并且Z10和Z11相互独立地是CH或氮,Z8和Z8*相互独立地是氧、硫或NH。
WL优选是被取代的或不被取代的亚苯基,基团
Figure A0080755400452
或者它们的取代或稠合衍生物,或者化学式IWL至IIIWL基团,
Figure A0080755400453
其中的基团可以在两个取向构建入,系数r是0,1,2或3,并且Z10和Z11相互独立地是CH或氮,Z8和Z8*相互独立地是氧、硫或NH。
对WL来说,结构式IIWL或IIIWL中的Z8优选是氧。
对于VL和XL优选的基团分别是-CO-NRL 10-,-NRL 10-CO-,-SO2-NRL 10-,-NRL 10-SO2-,-O-,-CH(NRL 14-SO2-RL 15)-,-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,CH(NRL 14-CO-NRL 14’RL 16)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-和CH(CO-NRL 14RL 15)-。
对于VL和XL特别优选的基团分别是-CH(NRL 14-SO2-RL 15)-,-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,CH(NRL 14-CO-NRL 14’RL 15)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-和CH(CO-NRL 14RL 15)-。
结构单元L的RL 10基团是氢原子,
支链或直链,被取代的或不被取代的C1-C6-烷基,例如如以上对RL 1所述的,优选甲基,
C1-C6-烷氧基烷基,例如甲氧基甲基,乙氧基甲基,叔丁氧基甲基,甲氧基乙基或乙氧基乙基,
C2-C6-烯基,例如如以上对RL 1所述的,优选烯丙基,
C3-C12-炔基,例如2-丙炔基,2-丁炔基,3-丁炔基,1-甲基-2-丙炔基,2-戊炔基,3-戊炔基,4-戊炔基,1-甲基-3-丁炔基,2-甲基-3-丁炔基,1-甲基-2-丁炔基,1,1-二甲基-2-丙炔基,1-乙基-2-丙炔基,2-己炔基,3-己炔基,4-己炔基,5-己炔基,1-甲基-2-戊炔基,1-甲基-2-戊炔基,1-甲基-3-戊炔基,1-甲基-4-戊炔基,2-甲基-3-戊炔基,2-甲基-4-戊炔基,3-甲基-4-戊炔基,4-甲基-2-戊炔基,1,1-二甲基-2-丁炔基,1,1-二甲基-3-丁炔基,1,2-二甲基-3-丁炔基,2,2-二甲基-3-丁炔基,1-乙基-2-丁炔基,1-乙基-3-丁炔基,2-乙基-3-丁炔基和1-乙基-1-甲基-2-丙炔基,优选炔丙基,
或CO-C1-C6-烷基,CO-O-C1-C6-烷基-或SO2-C1-C6-烷基,它们在各种情形下是由相应的CO-,CO-O-或SO2-基团和例如由以上所述的C1-C6-烷基组成,
被取代的或不被取代的C3-C7-环烷基,芳烷基,杂芳基或杂芳基烷基例如,在每种情况下以上对RL 1所述的,
被取代的或不被取代的CO-O-亚烷基-芳基,CO-亚烷基-芳基,CO-芳基,SO2-芳基,CO-杂芳基,或SO2-亚烷基-芳基,在各种情形下它们由相应的CO-,CO-O-或SO2基团和例如由如对RL 1所述的相应的芳烷基-,芳基-,杂芳基烷基和杂芳基组成。
此外RL 10可以和选自RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8的一个基团共同形成被取代的或不被取代的4-至8-元含有至多5个相同或不同的O、N或S杂原子的杂环。
对于RL 10特别优选的基团是氢,甲基,环丙基,烯丙基和炔丙基。
对于RL 11或RL 12,支链或直链C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基-或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基分别例如是指以上对RL 1解释的相应的基团。
对于RL 11或RL 12,支链或直链的C1-C4-烷氧基分别是指,例如甲氧基,乙氧基,丙氧基,1-甲基乙氧基,丁氧基,1-甲基丙氧基,2-甲基丙氧基或1,1-二甲基乙氧基。
对于RL 13,支链或直链的C1-C6-烷基,C2-C6-烯基,C2-C6-炔基或C1-C6-亚烷基-C3-C7环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳基烷基,杂芳基或杂芳烷基例如是指对RL 1的上述相应基团。
对RL 14和RL 14’来说,优选的基团分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基或C3-C12-炔基或者被取代的或不被取代的C3-C7-环烷基、芳基、杂芳基或芳烷基。
对RL 14和RL 14’来说,特别优选的基团分别是氢、甲基、环丙基、烯丙基或炔丙基。
RL 15是如上对RL 1所述的支链或直链的、被取代的或不被取代的C1-C6-烷基,优选支链或直链的、被取代的或不被取代的C1-C4-烷基,特别优选正丁基、2-甲基丙基、1-甲基乙基、
如上对RL 10所述的烷氧基烷基、
如上对RL 1所述的C1-C6-亚烷基-C3-C7-环烷基,优选-CH2-C3-C7-环烷基或-CH2-CH2-C3-C7-环烷基,
C6-C12-双环烷基或C7-C20-三环烷基如双环[4.4.0]癸烷基、双环-[2.2.2]-辛烷基、双环[3.2.1]-辛烷基、2,3-二氢化茚基、金刚烷基、降冰片基、降金刚烷基或樟脑-10-基,
C1-C6-亚烷基-C6-C12-双环烷基或C1-C6-亚烷基-C7-C20-三环烷基如-CH2-双环[4.4.0]癸烷基、-CH2-双环-[2.2.2]-辛烷基、-CH2-双环-[3.2.1]-辛烷基、-CH2-2,3-二氢化茚基、-CH2-金刚烷基、-CH2-降冰片基、-CH2-降金刚烷基或-CH2-樟脑-10-基,
如上对RL 1所述的C3-C7-环烷基、芳基、芳基烷基或杂芳基烷基,它们可以被至多三个相同或不同的基团所取代,
或者被至多三个相同或不同的基团所取代的并且含有至多三个相同或不同的O、N、S杂原子的3-到8-元、饱和的、不饱和的或芳香的杂环,其中两个基团可能一起形成稠合的、饱和的、不饱和的或芳香的碳环或含有至多三个相同或不同的O、N、S杂原子的杂环,并且该环可能被取代或不被取代,或者另一被取代的或不被取代的、饱和的、不饱和的或芳香的环可稠合在该环上。
此外RL 15和RL 14或RL 14*还可能一起形成任选含有至多两个另外的选自O、S或N中的杂原子的饱和的或不饱和的杂环。
RL 15和RL 14或RL 14*优选一起形成环状胺基作为C3-C7-杂环,这时基团与相同的氮原子相连,例如N-吡咯烷基、N-哌啶烷基、N-六氢化氮杂基、N-吗啉基或N-哌嗪基,对于含有游离胺质子的杂环如N-哌嗪基,游离胺质子可用常规胺保护基如甲基、苄基、Boc(叔丁氧基-羰基)、Z(苯甲氧基羰基)、甲苯磺酰基、-SO2-C1-C4-烷基、-SO2-苯基或-SO2-苄基置换。根据结构单元VL或XL,环状胺基NRL 15RL 14或NRL 15RL 14*也可以是酰胺、氨磺酰、尿烷或其他可能的结构单元的组成部分。
对RL 15来说,优选的基团是支链的或直链的、被取代的或不被取代的C1-C4-烷基或-CH2-C5-C7-环烷基、被取代的或不被取代的C5-C7-环烷基、苯基、1-萘基、2-萘基、-CH2-萘基、吡啶基、-CH2-吡啶基,亚乙基苯基,噻吩基,-CH2-噻吩基,噁唑基、-CH2-噁唑基,异噁唑基、-CH2-异噁唑基、喹啉基、异喹啉基、-CH2-喹啉基、-CH2-异喹啉基、金刚烷基、-CH2-金刚烷基、降冰片基、-CH2-降冰片基、樟脑-10-基或-CH2-樟脑-10-基。
对RL 16来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基、烷氧基烷基或C1-C6-亚烷基-C3-C7-环烷基、或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳烷基是指例如上述RL 15中提到的相应基团,优选氢、支链的或直链的、被取代的或不被取代的C1-C4-烷基或-CH2-C5-C7-环烷基、被取代的或不被取代的C5-C7-环烷基、苯基、1-萘基、2-萘基、-CH2-萘基、苄基、吡啶基、-CH2-吡啶基、亚乙基苯基、噻吩基、-CH2-噻吩基、噁唑基、-CH2-噁唑基、异噁唑基、-CH2-异噁唑基、金刚烷基、-CH2-金刚烷基。
对RL 16来说,特别优选的基团是支链的或直链的、被取代的或不被取代的C1-C4-烷基和被取代的或不被取代的苄基。
优选的结构单元L是由至少一个属于结构单元L基团的优选基团组成,而其他基团可以广泛变化。
特别优选的结构单元L是由结构单元L的优选基团组成。
G是下列结构式IG的结构单元:
Figure A0080755400491
其中结构单元G能够在两个取向构建入。
ZG是氧、硫或NRG 3,优选氧。
在结构单元G的优选实施方案中,取代模式被固定为通式IGB
Figure A0080755400492
其中结构单元G在这种情况也能够在两个取向构建入。
在结构单元G的特别优选的实施方案中,取代模式被固定为通式IGB,构建入结构单元G以使结构单元E连接在4位碳原子上并且结构单元L连接在1位氮原子上。
结构单元G中的RG 1和RG 2分别是氢、CN、NO2、卤素、支链的或直链的、被取代的或不被取代的
C1-C6-烷基如被取代的或不被取代的甲基、乙基、丙基、1-甲基乙基、丁基、1-甲基丙基、2-甲基丙基、1,1-二甲基乙基、戊基、1-甲基丁基、2-甲基丁基、1,2-二甲基丙基、1,1-二甲基丙基、2,2-二甲基丙基、1-乙基丙基、己基、1-甲基戊基、1,2-二甲基丁基、1,3-二甲基丁基、2,3-二甲基丁基、1,1-二甲基丁基、2,2-二甲基丁基、3,3-二甲基丁基、1,1,2-三甲基丙基、1,2,2-三甲基丙基、1-乙基丁基、2-乙基丁基或1-乙基-2-甲基丙基,
C2-C6-烯基,如被取代的或不被取代的乙烯基、2-丙烯基、2-丁烯基、3-丁烯基、1-甲基-2-丙烯基、2-甲基-2-丙烯基、2-戊烯基、3-戊烯基、4-戊烯基、1-甲基-2-丁烯基、2-甲基-2-丁烯基、3-甲基-2-丁烯基、1-甲基-3-丁烯基、2-甲基-3-丁烯基、3-甲基-3-丁烯基、1,1-二甲基-2-丙烯基、1,2-二甲基-2-丙烯基、1-乙基-2-丙烯基、2-己烯基、3-己烯基、4-己烯基、5-己烯基、1-甲基-2-戊烯基、2-甲基-2-戊烯基、3-甲基-2-戊烯基、4-甲基-2-戊烯基、3-甲基-3-戊烯基、4-甲基-3-戊烯基、1-甲基-4-戊烯基、2-甲基-4-戊烯基、3-甲基-4-戊烯基、4-甲基-4-戊烯基、1,1-二甲基-2-丁烯基、1,1-二甲基-3-丁烯基、1,2-二甲基-2-丁烯基、1,2-二甲基-3-丁烯基、1,3-二甲基-2-丁烯基、1,3-二甲基-3-丁烯基、2,2-二甲基-3-丁烯基、2,3-二甲基-2-丁烯基、2,3-二甲基-3-丁烯基、1-乙基-2-丁烯基、1-乙基-3-丁烯基、2-乙基-2-丁烯基、2-乙基-3-丁烯基、1,1,2-三甲基-2-丙烯基、1-乙基-1-甲基-2-丙烯基或1-乙基-2-甲基-2-丙烯基,
C2-C6-炔基,如被取代的或不被取代的乙炔基、2-丙炔基、2-丁炔基、3-丁炔基、1-甲基-2-丙炔基、2-戊炔基、3-戊炔基、4-戊炔基、1-甲基-3-丁炔基、2-甲基-3-丁炔基、1-甲基-2-丁炔基、1,1-二甲基-2-丙炔基、1-乙基-2-丙炔基、2-己炔基、3-己炔基、4-己炔基、5-己炔基、1-甲基-2-戊炔基、1-甲基-2-戊炔基、1-甲基-3-戊炔基、1-甲基-4-戊炔基、2-甲基-3-戊炔基、2-甲基-4-戊炔基、3-甲基-4-戊炔基、4-甲基-2-戊炔基、1,1-二甲基-2-丁炔基、1,1-二甲基-3-丁炔基、1,2-二甲基-3-丁炔基、2,2-二甲基-3-丁炔基、1-乙基-2-丁炔基、1-乙基-3-丁炔基、2-乙基-3-丁炔基或1-乙基-1-甲基-2-丙炔基,
支链的或直链的、被取代的或不被取代的C1-C4-亚烷基-O-RG 4、C1-C4-亚烷基-CO-ORG 4、C1-C4-亚烷基-CO-RG 4、C1-C4-亚烷基-SO2-NRG 5RG 6、C1-C4-亚烷基-CO-NRG 5RG 6、C1-C4-亚烷基-NRG 5RG 6或C1-C4-亚烷基-SRG 4,它们是由支链的或直链的、被取代的或不被取代C1-C4-亚烷基例如亚甲基、亚乙基、亚丙基、亚正丁基、亚异丁基或亚叔丁基、相应的-O-、-CO-、-S-、-N基和以下所述的末端基RG 4、RG 5和RG 6组成,
被取代的或不被取代的
C3-C7-环烷基,如被取代的或不被取代的环丙基、环丁基、环戊基、环己基或环庚基,
C3-C7-杂环烷基,如被取代的或不被取代的氮杂环丙烷基、二氮杂环丙烷基、环氧乙基、氧杂氮杂环丙烷基、氧杂环丁烷基、硫杂丙环基、thietanyl、吡咯烷基、哌嗪基、吗啉基、哌啶基、四氢呋喃基、四氢吡喃基、1,4-二噁烷基、六氢氮杂基、氧杂环庚三烯基(oxepanyl)、1,2-氧硫杂戊环基(1,2-oxathiolanyl)或噁唑烷基,
C3-C7-杂环烯基,如被取代的或不被取代的氮杂环丙烯基、二氮杂环丙烯基、硫杂环丙烯基、thietyl、吡咯啉基、噁唑啉基、氮杂基、氧杂环庚三烯基(oxepinyl)、α-吡喃基、β-吡喃基、γ-吡喃基、二羟基吡喃基、2,5-二氢吡咯啉基或4,5-二氢噁唑基,
支链的或直链的、被取代的或不被取代的C1-C4-亚烷基-C3-C7-环烷基,它们例如由支链的或直链的C1-C4-亚烷基如亚甲基,亚乙基、亚丙基、亚正丁基、亚异丁基、或亚叔丁基和例如上述C3-C7-环烷基组成。
支链的或直链的、被取代的或不被取代的C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,它们是由被取代的或不被取代的C1-C4-亚烷基例如亚甲基、亚乙基、亚丙基、亚正丁基、亚异丁基或亚叔丁基、以及例如前面所述的C3-C7-杂环烷基或C3-C7-杂环烯基组成,优选的基团是在环部分含有一个或两个选自N、O或S的杂原子并且至多两个双键的那些基团,
被取代的或不被取代的
芳基,优选被取代的或不被取代的苯基、1-萘基或2-萘基,
芳烷基,优选被取代的或不被取代的苄基或苯乙基,
杂芳基,优选被取代的或不被取代的2-吡啶基、3-吡啶基、4-吡啶基、2-呋喃基、3-呋喃基、2-吡咯基、3-吡咯基、2-噻吩基、3-噻吩基、2-噻唑基、4-噻唑基、5-噻唑基、2-噁唑基、4-噁唑基、5-噁唑基、2-嘧啶基、4-嘧啶基、5-嘧啶基、6-嘧啶基、3-吡唑基、4-吡唑基、5-吡唑基、3-异噻唑基、4-异噻唑基、5-异噻唑基、2-咪唑基、4-咪唑基、5-咪唑基、3-哒嗪基、4-哒嗪基、5-哒嗪基、6-哒嗪基、3-异噁唑基、4-异噁唑基、5-异噁唑基、噻二唑基、噁二唑基或三嗪基或其稠合的衍生物,例如吲唑基、吲哚基、苯并噻吩基、苯并呋喃基、二氢吲哚基、苯并咪唑基、苯并噻唑基、苯并噁唑基、喹啉基或异喹啉基,
杂芳基烷基,优选被取代的或不被取代的-CH2-2-吡啶基、-CH2-3-吡啶基、-CH2-4-吡啶基、-CH2-2-噻吩基、-CH2-3-噻吩基、-CH2-2-噻唑基、-CH2-4-噻唑基、-CH2-5-噻唑基、-CH2-CH2-2-吡啶基、-CH2-CH2-3-吡啶基、-CH2-CH2-4-吡啶基、-CH2-CH2-2-噻吩基、-CH2-CH2-3-噻吩基、-CH2-CH2-2-噻唑基、-CH2-CH2-4-噻唑基或-CH2-CH2-5-噻唑基,
或者
基团-S-RG 4、-O-RG 4、-SO-RG 4、-SO2-RG 4、-CO-ORG 4、-O-CO-RG 4、-O-CO-NRG 5RG 6、-SO2-NRG 5RG 6、-CO-NRG 5RG 6、-NRG 5RG 6、CO-RG 4
RG 1和RG 2也可能一起形成被取代的或不被取代的、饱和的或不饱和的或芳香的3-到9-元碳环、多碳环、含有至多4个选自O、N、S的杂原子的杂环或杂多环。
对结构单元G中的RG 1来说,优选的基团是氢、支链的或直链的、被取代的或不被取代C1-C6-烷基,优选CF3、C2-C6-烯基、C2-C6-炔基、C1-C4-亚烷基-ORG 4、被取代的或不被取代的芳基、芳烷基、杂芳基或杂芳烷基或-O-RG 4
对结构单元G中的RG 2来说,优选的基团是氢、CN、卤素、支链的或直链的、被取代的或不被取代C1-C6-烷基,优选CF3、被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基、-SO-RG 4、-SO2-RG 4、-CO-ORG 4、-SO2-NRG 5RG 6、-CO-NRG 5RG 6、-NRG 5RG 6、CO-RG 4、C1-C4-亚烷基-CO-ORG 4、C1-C4-亚烷基-SO2-NRG 5RG 6、C1-C4-亚烷基-CO-NRG 5RG 6或C1-C4-亚烷基-NRG 5RG 6或者被取代的或不被取代的C1-C4-亚烷基-C3-C7-环烷基、C3-C7-杂环烷基、C3-C7-杂环烯基、C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,最后四个基团优选在环部分含有一个或两个选自N、O或S杂原子和至多两个双键。
结构单元G中的RG 2特别优选支链的或直链的、被取代的或不被取代C1-C6-烷基,被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基、-CO-ORG 4、-CO-NRG 5RG 6、-NRG 5RG 6、C1-C4-亚烷基-CO-NRG 5RG 6或C1-C4-亚烷基-NRG 5RG 6或者被取代的或不被取代的C3-C7-杂环烷基、C3-C7-杂环烯基、C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,其中最后四个基团优选在环部分含有一个或两个选自N、O或S杂原子和至多两个双键。
RG 3是氢、羟基、CN、支链或直链的、被取代的或不被取代的
C1-C6-烷基,如上述RG 1中所描述的,
C1-C4-烷氧基,如上述RL 11中所描述的,
被取代的或不被取代的C3-C7-环烷基、芳基或芳烷基,如上述RG 1中所描述的各种情况,
被取代的或不被取代的-O-C3-C7-环烷基、-O-芳基或-O-亚烷基-芳基,它是例如在每种情况下由-O-基团和上述RG 1中所描述的相应基团所组成,
对于RG 4、RG 4*、RG 5和RG 6来说,支链的或直链的、被取代的或不被取代的C1-C8-烷基分别是例如上面对RG 1所提及的C1-C6-烷基以及庚基和辛基。
对RG 4、RG 4*、RG 5和RG 6来说,支链或直链的、被取代的或不被取代的C1-C8-烷基的优选取代基分别是卤素、羟基、C1-C4-烷氧基、-CN、-COOH和-CO-O-C1-C4-烷基。
对RG 4、RG 4*、RG 5和RG 6来说,支链或直链的、被取代的或不被取代的C2-C6-烯基、C2-C6-炔基或C1-C4-亚烷基-C3-C7-环烷基、被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基分别例如是上述RG 1中所述的相应基团。
对RG 4、RG 4*、RG 5和RG 6来说,优选的支链或直链的、被取代的或不被取代的-C1-C5-亚烷基-C1-C4-烷氧基分别是甲氧基亚甲基、乙氧基亚甲基、正丁氧基亚甲基、甲氧基亚乙基或乙氧基亚乙基。
对RG 4、RG 4*、RG 5和RG 6来说,优选的支链或直链的、被取代的或不被取代的单和双烷基氨基亚烷基或酰基氨基亚烷基分别是支链或直链的、被取代的或不被取代的-C1-C4-亚烷基-NH(C1-C4-烷基)、-C1-C4-亚烷基-N(C1-C4-烷基)2和-C1-C4-亚烷基-NH-CO-C1-C4-烷基。
对RG 4、RG 4*、RG 5和RG 6来说,优选的被取代的或不被取代的杂环烷基、杂环烯基、C1-C4-亚烷基-杂环烷基或C1-C4-亚烷基-杂环烯基分别是上述RG 1中所述的C3-C7-杂环烷基、C3-C7-杂环烯基、C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基。
对RG 4、RG 4*、RG 5和RG 6来说,特别优选的被取代的或不被取代的杂环烷基、杂环烯基、C1-C4-亚烷基-杂环烷基或C1-C4-亚烷基-杂环烯基分别是上述RG 1中所述的C3-C7-杂环烷基、C3-C7-杂环烯基、C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,其中在环部分含有一个或两个选自N、O或S的杂原子至多含有两个双键。
RG 5和RG 6也可能分别是-SO2-RG 4、-CO-O-RG 4、-CO-NRG 4RG 4*或-CO-RG 4,其中RG 4*是不同于RG 4的RG 4基团。
优选的结构单元G是由至少一个属于结构单元G的优选基团、或者结构单元G的优选取代模式组成,其他基团可以广泛变化。
结构单元G特别优选的是由结构单元G的特别优选的基团组成。
最佳的结构单元G是由结构单元G的优选基团和结构单元G的优选取代模式组成。
结构单元B是指这样的结构单元,它含有至少一个在生理条件下作为氢受体能够形成氢键的原子,其中至少一个氢受体原子沿结构单元骨架沿最短的可能途径与结构单元G之间具有4到13个原子键。结构单元B的结构骨架的排列可以广泛变化。
在生理条件下,作为氢受体能够形成氢键的适当原子的例子是具有路易斯碱特性的原子例如杂原子氮、氧或硫。
生理条件是指在有机体部位存在的pH值,在此配体与受体相互作用。在本发明的情况中,生理条件具有的pH值例如是5到9。
在优选的实施方案中,结构单元B是具有通式IB的结构单元:
                     A-E-           IB其中A和E具有下列含义:A是选自于下列组的结构单元:
含有至多4个选自O、N或S杂原子的4-至8-元单环饱和的、不饱和的或芳香烃,其中在各种情况下,可能存在的环氮或碳可能分别被取代,条件是结构单元A中存在至少一个选自O、N或S的杂原子,或者
含有至多6个选自O、N或S杂原子的9-至14-元多环饱和的、不饱和的或芳香烃,其中在各种情况下,可能存在的环氮或碳可能分别被取代,条件是结构单元A中存在至少一个选自O、N或S的杂原子,
基团:其中
ZA 1是氧、硫或被取代的或不被取代的氮,优选氧或氮,并且
ZA 2是被取代的或不被取代的氮、氧或硫,优选氮,或者基团:
Figure A0080755400552
其中
RA 18、RA 19分别是氢、支链或直链的、被取代的或不被取代的C1-C8-烷基、C2-C6-烯基、C2-C6-炔基或C1-C5-亚烷基-C1-C4-烷氧基、单或双烷基氨基亚烷基或酰基氨基亚烷基或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳烷基、C1-C4-亚烷基-杂环烷基、C1-C4-亚烷基-杂环烯基或杂芳烷基或者-SO2-RG 4、-CO-O-RG 4、-CO-NRG 4RG 4*或-CO-RG 4,并且E是将结构单元A与结构单元G共价连接的间隔结构单元,其中沿结构单元骨架E上最短的可能途径的原子键数是3到12。
在特别优选的实施方案中,结构单元A是选自通式IA 1到IA 19的结构单元的组:
其中:
m,p,q相互独立地是1,2或3,
RA 1、RA 2分别是氢、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或CO-C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、杂芳基烷基或C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、CO-NRA 15RA 16或SO2NRA 15RA 16或者RA 1和RA 2一起是稠合的、被取代的或不被取代的、5-或6-元、不饱和的或芳香的碳环或杂环,其中该杂环可以含有至多3个选自O、N或S的杂原子,
RA 13、RA 13*分别是氢、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基-C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16或SO2-NRA 15RA 16或CO-NRA 15RA 16
其中RA 14是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、亚烷基-C1-C4-烷氧基、C2-C6-烯基、C2-C6-炔基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基,
RA 15、RA 16分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、CO-C1-C6-烷基、SO2-C1-C6-烷基、COO-C1-C6-烷基、CO-NH-C1-C6-烷基、芳烷基、COO-亚烷基-芳基、SO2-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-NH-亚烷基-杂芳基或杂芳烷基或者被取代的或不被取代的C3-C7-环烷基、芳基、CO-芳基、CO-NH-芳基、SO2-芳基、杂芳基、CO-NH-杂芳基或CO-杂芳基,
RA 3、RA 4分别是氢、-(CH2)n-(XA)j-RA 12或者两个基团一起是3-到8-元、饱和的或不饱和的或芳香的N杂环,该杂环还可含有两个其他相同或不同的杂原子O、N或S,该环可能被取代或不被取代,或者另外一个被取代的或不被取代的饱和的或不饱和的或芳香环可能与该环稠合,
其中
n是0,1,2或3,
j是0或1,
XA
-CO-,-CO-N(RX 1)-,-N(RX 1)-CO-,-N(RX 1)-CO-N(RX 1*)-,
-N(RX 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RX 1)-,-SO2-O-,
-CO-O-,-O-CO-,-O-CO-N(RX 1)-,-N(RX 1)-或
-N(RX 1)-SO2-,
RA 12是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、被C1-C4-烷基或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基或者被至多3个相同或不同的基团取代的、3-到6-元、饱和的或不饱和的杂环,该杂环可含有至多3个相同或不同的杂原子O、N、S,C3-C7-环烷基、芳基、杂芳基,其中两个基团可能一起形成稠合的、饱和的或不饱和的或芳香的碳环或杂环,其中杂环可以含有至多3个选自O、N或S的杂原子,并且该环可能被取代或不被取代,或者另外一个被取代的或不被取代的饱和的或不饱和的或芳香环可能与该环稠合,或者RA 12能够与RX 1或RX 1*一起形成饱和的或不饱和的C3-C7-杂环,它任选含有至多2个另外的选自O、S或N的杂原子,
RX 1、RX 1*分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、杂芳基、CO-杂芳基或SO2-亚烷基-芳基,
RA 5是支链或直链的、被取代的或不被取代的C1-C6-烷基、芳烷基、C3-C7-环烷基或C1-C4-亚烷基-C3-C7-环烷基或者被取代的或不被取代的芳基、杂芳基、杂环烷基或杂环烯基,
RA 6、RA 6*是氢、支链或直链的、被取代的或不被取代的C1-C4-烷基、-CO-O-C1-C4-烷基、芳烷基、-CO-O-亚烷基-芳基、-CO-O-烯丙基、-CO-C1-C4-烷基、-CO-亚烷基-芳基、C3-C7-环烷基或-CO-烯丙基或者在结构单元IA 7中的两个基团RA 6和RA 6*一起形成被取代的或不被取代的、饱和的或不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多两个另外的不同或相同的杂原子O、N、S,
RA 7是氢、-OH、-CN、-CONH2、支链或直链的、被取代的或不被取代的C1-C4-烷基、C1-C4-烷氧基、C3-C7-环烷基或-O-CO-C1-C4-烷基或被取代的或不被取代的芳烷基、-O-亚烷基-芳基、-O-CO-芳基、-O-CO-亚烷基-芳基或-O-CO-烯丙基,或RA 6和RA 7两个基团一起形成被取代的或不被取代的、不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多两个另外的不同或相同的杂原子O、N、S,
RA 8是氢、支链或直链的、被取代的或不被取代的C1-C4-烷基、CO-C1-C4-烷基、SO2-C1-C4-烷基或CO-O-C1-C4-烷基或被取代的或不被取代的芳基、CO-芳基、SO2-芳基、CO-O-芳基、CO-亚烷基-芳基、SO2-亚烷基-芳基、CO-O-亚烷基-芳基或亚烷基-芳基,
RA 9、RA 10分别是氢、-CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16,或者在结构单元IA 14中的两个基团RA 9和RA 10一起形成5-到7-元、饱和的或不饱和的或芳香碳环或杂环,它可以含有至多三个不同或相同的杂原子O、N、S并且被至多三个相同或不同的基团取代或不被取代,
RA 11是氢、-CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16
RA 17是氢或者在结构单元IA 16中的两个基团RA 9和RA 17一起形成5-到7-元、饱和的或不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多三个不同或相同的杂原子O、N、S并且被至多三个相同或不同的基团取代或不被取代,
RA 18、RA 19分别是氢、支链或直链的、被取代的或不被取代的C1-C8-烷基、C2-C6-烯基、C2-C6-炔基、C1-C5-亚烷基-C1-C4-烷氧基、单-和双烷基氨基亚烷基或酰基氨基亚烷基、或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳烷基、C1-C4-亚烷基-杂环烷基、C1-C4-亚烷基-杂环烯基或杂芳烷基、或者-SO2-RG 4、-CO-O-RG 4、-CO-NRG 4RG 4*或-CO-RG 4
Z1、Z2、Z3、Z4分别是氮、C-H、C-卤素或支链的或直链的、被取代的或不被取代的C-C1-C4-烷基或C-C1-C4-烷氧基,
Z5是NRA 8、氧或硫。
在更优选的实施方案中,结构单元A是通式IA 1、IA 4、IA 7、IA 8、IA 9、IA 14或IA 15的结构单元。
对RA 1或RA 2来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基分别是指例如上述对RG 1所述的相应基团,优选甲基或三氟甲基。
对结构单元IA 1、IA 2、IA 3或IA 17的RA 1或RA 2来说,支链的或直链的、被取代的或不被取代的CO-C1-C6-烷基是由例如CO基团和上述对RA 1或RA 2所述的支链的或直链的、被取代的或不被取代的C1-C6-烷基组成。
对RA 1或RA 2来说,被取代的或不被取代的杂芳基、杂芳烷基、芳基、芳烷基或C3-C7-环烷基分别是指例如上述对RG 1所述的相应基团。
对RA 1或RA 2来说,被取代的或不被取代的CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、CO-NRA 15RA 16或SO2-NRA 15RA 16是由例如基团CO-O、O、S、N、CO-N或SO2-N和以下详细描述的基团RA 14、RA 15和RA 16组成。
RA 1和RA 2也可能两个一起形成稠合的、被取代的或不被取代的、5-或6-元不饱和的或芳香碳环或杂环,该杂环可以含有至多三个选自O、N或S的杂环原子。
RA 13和RA 13*分别是氢、CN、卤素如氟、氯、溴或碘。
支链的或直链的、被取代的或不被取代的C1-C6-烷基,例如如上述RG 1中所述,优选甲基或三氟甲基或者
被取代的或不被取代的芳基、芳烷基、杂芳基或C3-C7-环烷基或CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2NRA 15RA 16或CO-NRA 15RA 16,正如上述RA 1中所述的各种情况。
对RA 13和RA 13*来说,优选的基团是氢、F、Cl或支链的或直链的、被取代的或不被取代的C1-C6-烷基、被取代的或不被取代的芳基或芳烷基或CO-O-RA 14、O-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16
对结构单元A中的RA 14来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基、C3-C7-环烷基、亚烷基-环烷基、亚烷基-C1-C4-烷氧基、C2-C6-烯基或C2-C6-炔基是指例如上述RG 1中所述的相应基团。
对结构单元A中的RA 14来说,被取代的或不被取代的芳基、芳烷基、杂芳基或烷基杂芳基是指例如上述RG 1中所述的相应基团。
对RA 14来说,优选的基团是氢、支链的或直链的、被取代的或不被取代的C1-C6-烷基和被取代的或不被取代的苄基。
对RA 15或RA 16来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基或芳烷基或者被取代的或不被取代的C3-C7-环烷基、芳基、杂芳基或杂芳烷基是分别指例如上述RA 14中所述的相应基团。
对RA 15或RA 16来说,支链的或直链的、被取代的或不被取代的CO-C1-C6-烷基、SO2-C1-C6-烷基、COO-C1-C6-烷基、CO-NH-C1-C6-烷基、COO-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-NH-亚烷基-杂芳基或SO2-亚烷基-芳基或者被取代的或不被取代的CO-芳基、SO2-芳基、CO-NH-芳基、CO-NH-杂芳基或CO-杂芳基是例如由相应的基团-CO-、-SO2-、-CO-O-、-CO-NH-和相应的上述支链的或直链的、被取代的或不被取代的C1-C6-烷基、杂芳烷基或芳烷基或者相应的被取代的或不被取代的芳基或杂芳基组成
对RA 3或RA 4来说,基团-(CH2)n-(XA)j-RA 12分别是指由相应的-(CH2)n-、(XA)j和RA 12基团组成的基团。其中,n是0、1、2或3而j是0或1。
XA是选自于下组双重键合的基团:-CO-、-CO-N(RX 1)-、-N(RX 1)-CO-、-N(RX 1)-CO-N(RX 1*)-、-N(RX 1)-CO-O-、-O-、-S-、-SO2-、-SO2-N(RX 1)-、-SO2-O-、-CO-O-、-O-CO-、-O-CO-N(RX 1)-、-N(RX 1)-或-N(RX 1)-SO2-。
RA 12是氢、
如RG 1中所述的支链的或直链的、被取代的或不被取代的C1-C6-烷基、
被C1-C4-烷基或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基,例如在上述RL 9中所述的、
或者3-到6-元饱和的或不饱和的杂环,该杂环可以被至多三个相同或不同的基团取代并且可以含有至多3个不同的或相同的杂原子O、N、S,例如被取代的或不被取代的2-吡啶基、3-吡啶基、4-吡啶基、2-呋喃基、3-呋喃基、2-吡咯基、3-吡咯基、2-噻吩基、3-噻吩基、2-噻唑基、4-噻唑基、5-噻唑基、2-噁唑基、4-噁唑基、5-噁唑基、2-嘧啶基、4-嘧啶基、5-嘧啶基、6-嘧啶基、3-吡唑基、4-吡唑基、5-吡唑基、3-异噻唑基、4-异噻唑基、5-异噻唑基、2-咪唑基、4-咪唑基、5-咪唑基、3-哒嗪基、4-哒嗪基、5-哒嗪基、6-哒嗪基、2-(1,3,4-噻二唑基)、2-(1,3,4)-噁二唑基、3-异噁唑基、4-异噁唑基、5-异噁唑基或三嗪基。
RA 12也可能和RX 1或RX 1*一起形成饱和的或不饱和的C3-C7-杂环,该杂环可以含有至多2个其他选自O、S或N中的杂原子。
优选RA 12和RX 1或RX 1*一起形成环状胺基作为C3-C7-杂环,这时基团与相同的氮原子相连,例如N-吡咯烷基、N-哌啶基、N-六氢化氮杂基、N-吗啉基或N-哌嗪基,对于含有游离胺质子的杂环如N-哌嗪基,游离胺质子可用常规胺保护基如甲基、苄基、Boc(叔丁氧基羰基)、Z(苯甲氧基羰基)、甲苯磺酰基、-SO2-C1-C4-烷基、-SO2-苯基或-SO2-苄基置换。
对RX 1和RX 1*来说,支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或者被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、杂芳基、CO-杂芳基或SO2-亚烷基-芳基分别是指例如上述对RL 14和RL 14*中所述的基团。
对RX 1和RX 1*来说,优选的基团分别是氢、甲基、环丙基、烯丙基和炔丙基。
RA 3和RA 4也可能两个一起形成3-到8-元、饱和的、不饱和的或芳香N杂环,该杂环还可以含有两个其他相同或不同的选自O、N或S的杂原子,该环也可能被取代或不被取代或者可能另外一个被取代的或不被取代的、饱和的或不饱和的或芳香环稠合到该环上。
RA 5是支链的或直链的、被取代的或不被取代的C1-C6-烷基、芳烷基、C1-C4-烷基-C3-C7-环烷基或C3-C7-环烷基或者被取代的或不被取代的芳基、杂芳基、杂环烷基或杂环烯基,例如上述RG 4、RG 5和RG 6中所述的基团。
RA 6和RA 6*分别是氢、支链的或直链的、被取代的或不被取代的
C1-C4-烷基、例如被取代的或不被取代的甲基、乙基、丙基、1-甲基乙基、丁基、1-甲基丙基、2-甲基丙基或1,1-二甲基乙基,
-CO-O-C1-C4-烷基或-CO-C1-C4-烷基,例如由-CO-O-或-CO-和上述的C1-C4-烷基组成。
如上述RG 1中所述的芳烷基,
-CO-O-亚烷基-芳基或-CO-亚烷基-芳基,例如由-CO-O-或-CO-和上述的芳烷基组成,
-CO-O-烯丙基或-CO-烯丙基
或者例如上述RG 1中所述的C3-C7-环烷基。
此外结构单元IA 7中的RA 6和RA 6*也可能一起形成被取代的或不被取代的、饱和的或不饱和的或芳香杂环,该杂环中除了环氮外还可以含有至多2个其他的不同或相同的杂原子O、N、S。
RA 7是氢、-OH、-CN、-CONH2、支链的或直链的、被取代的或不被取代的C1-C4-烷基,例如如上述RA 6中所述的,C1-C4-烷氧基、芳烷基或C3-C7-环烷基,例如如上述RL 14中所述的,由-O-CO-和例如上述C1-C4-烷基组成的支链的或直链的、被取代的或不被取代的-O-CO-C1-C4-烷基,或者由-O-或-O-CO-和上述RG 1中所述的相应基团组成的被取代的或不被取代的-O-亚烷基-芳基、-O-CO-芳基、-O-CO-亚烷基-芳基或-O-CO-烯丙基。
此外RA 6和RA 7两个基团可能一起形成被取代的或不被取代的、不饱和的或芳香杂环,该杂环除了环氮外还可以含有至多两个另外的不同或相同的杂原子O、N、S。
对结构单元A中的RA 8来说,支链的或直链的、被取代的或不被取代的C1-C4-烷基或被取代的或不被取代的芳基或芳烷基是指例如上述RA 15中所述的相应基团,其中CO-C1-C4-烷基、SO2-C1-C4-烷基、CO-O-C1-C4-烷基、CO-芳基、SO2-芳基、CO-O-芳基、CO-亚烷基-芳基、SO2-亚烷基-芳基或CO-O-亚烷基-芳基类似于其他组合基团是由CO、SO2或COO和例如上述对RA 15所述的相应的C1-C4-烷基、芳基或芳烷基组成,这些基团可以被取代或不被取代。
对RA 9或RA 10来说,在各种情况下的支链的或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基或C3-C7-环烷基分别是指上述对RA 14所述的相应的基团,优选甲基或三氟甲基。
对RA 9或RA 10来说,在各种情况下的CO-O-RA 14、O-RA 14、S-RA 14、SO2-NRA 15RA 16、NRA 15RA 16或CO-NRA 15RA 16分别是指例如上述对RA 13所述的相应的基团。
结构单元IA 14中的RA 9和RA 10两个基团也可能一起形成5-到7-元、饱和的或不饱和的或芳香碳环或杂环,它可以含有至多三个不同或相同的杂原子O、N、S并且可以被至多三个相同或不同的基团取代或不被取代。
在这种情况中,取代基尤其是指卤素、CN、支链的或直链的、被取代的或不被取代的C1-C4-烷基,例如甲基或三氟甲基或者基团O-RA 14、S-RA 14、NRA 15RA 16、CO-NRA 15RA 16或-((RA 8)HN)C=N-RA 7
对RA 11来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16是指例如上述对RA 9所述的相应的基团。
结构单元IA 15中的RA 9和RA 17两个基团也可能一起形成5-到7-元、饱和的或不饱和的或芳香杂环,该杂环除了环氮外还可以含有至多三个不同或相同的杂原子O、N、S并且可以被至多三个相同或不同的基团取代或不被取代。
对RA 18和RA 19来说,支链或直链的、被取代的或不被取代的C1-C8-烷基、C2-C6-烯基、C2-C6-炔基、C1-C5-亚烷基-C1-C4-烷氧基、单-和双烷基氨基亚烷基或酰基氨基亚烷基或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳烷基、C1-C4-亚烷基-杂环烷基、C1-C4-亚烷基-杂环烯基或杂芳烷基或-SO2-RG 4、-CO-ORG 4、-CO-NRG 4RG 4*或-CO-RG 4分别是指例如上述对RG 5所述的基团,优选氢或支链或直链的、被取代的或不被取代的C1-C8-烷基。
Z1、Z2、Z3、Z4分别是氮、C-H、C-卤素如,例如C-F、C-Cl、C-Br或C-I或支链或直链的、被取代的或不被取代的C-C1-C4-烷基,它是由碳基和例如上述对RA 6所述C1-C4-烷基组成,或者支链或直链的、被取代的或不被取代的C-C1-C4-烷氧基,它是由碳基和例如上述对RA 7所述C1-C4-烷氧基组成。
Z5是氧、硫或NRA 8
优选的结构单元A是由至少一个属于结构单元A的基团中的优选基团组成,而其余的基团可以广泛变化。
特别优选的结构单元A是由结构单元A的优选基团组成。
在优选的实施方案中,分隔结构单元E是指由支链的或直链的、被取代的或不被取代的并且含有杂原子的脂肪族C2-C30-烃基和/或由4-到20-元、被取代的或不被取代的和含有杂原子的脂肪族或芳香族单-或多环烃基组成的结构单元。
在特别优选的实施方案中,间隔结构单元E是具有通式IE的结构单元:
                     -(NRE 1)i-E1-(UE)h-         IE
其中:
UE是氧、硫或NRE 2
h是0或1,
i是0或1,
RE 1,RE 2分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基、CO-NH-C1-C6-烷氧基烷基、CO-NH-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的杂芳基、芳基烷基、C3-C7-环烷基、CO-O-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、CO-NH-芳基、SO2-芳基、CO-杂芳基、SO2-亚烷基-芳基、SO2-杂芳基或SO2-亚烷基-杂芳基,
E1是具有结构式IE1的结构单元:-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4-(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-IE1其中k2、k4、k6是0或1,k1、k3、k5、k7是0,1或2,RE 3、RE 4、RE 5、RE 6、RE 7、RE 8、RE 9、RE 10分别是氢、卤素、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基、-(CH2)X-(YE)ZRE 11、被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,或在每种情况下相互独立地,两个基团RE 3和RE 4或RE 5和RE 6或RE 7和RE 8或RE 9和RE 10一起是3-7元被取代的或不被取代的饱和的或不饱和的碳环或杂环,其中杂环可以含有至多3个选自O、N、S中的杂原子,x是0、1、2、3或4,z是0或1,YE是-CO-,-CO-N(Ry 2)-,-N(Ry 2)-CO-,-N(Ry 2)-CO-N(Ry 2*)-,-N(Ry 2)-CO-O-,-O-,-S-,-SO2-,-SO2-N(Ry 2)-,-SO2-O-,-CO-O-,-O-CO-,-O-CO-N(Ry 2)-,-N(Ry 2)-或-N(Ry 2)-SO2-,Ry 2、Ry 2*分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C8-炔基、C2-C6-烯基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的杂芳基、杂芳基烷基、芳烷基、C3-C7-环烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、CO-杂芳基或SO2-亚烷基-芳基,RE 11是氢、羟基、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基、被取代的或不被取代的C3-C7-环烷基、芳基、杂芳基或芳基烷基、被C1-C4-烷基或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基、被取代的或不被取代的C6-C12-双环烷基、C1-C6-亚烷基-C6-C12-双环烷基、C7-C20-三环烷基或C1-C6-亚烷基-C7-C20-三环烷基,或3-到8-元饱和的或不饱和的杂环,该杂环被至多三个相同的或不同的基团取代并且可以含有至多三个不同的或相同的O、N、S杂原子,其中两个基团一起可能会形成稠合的、饱和的、不饱和的或芳香的碳环或杂环,该杂环可含有至多三个相同的或不同的O、N、S杂原子,并且该环可能被取代或不被取代,或者另一被取代的或不被取代的、饱和的、或不饱和的或芳香环可与该环稠合,或者RE 11与RY 2或RY 2*一起形成饱和的或不饱和的C3-C7-杂环,该杂环可以含有至多两个另外的选自O、S、N的杂原子,LE、TE分别是CO、CO-NRE 12、NRE 12-CO、硫、SO、SO2、SO2-NRE 12、NRE 12-SO2、CS、CS-NRE 12、NRE 12-CS、CS-O、O-CS、CO-O、O-CO、氧、亚乙炔基、CRE 13-O-CRE 14、C(=CRE 13RE 14)、CRE 13=CRE 14、-CRE 13(O RE 15)-CHRE 14-、-CHRE 13-CRE 14(ORE 15)-,RE 12是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C8-炔基、被取代的或不被取代的C3-C7-环烷基、杂芳基、芳基烷基或杂芳基烷基或CO-RE 16、COORE 16或SO2-RE 16,RE 13、RE 14分别是氢、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C4-烷氧基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,RE 15是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,RE 16是氢、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或C1-C5-亚烷基-C1-C4-烷氧基或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳基烷基、C1-C4-亚烷基-C3-C7-杂环烷基、C1-C4-亚烷基-C3-C7-杂环烯基或杂芳基烷基并且QE是被取代的或不被取代的4-到11-元单-或多环脂族或芳香烃,它可以含有至多6个双键和至多6个相同或不同的选自于N、O、S杂原子,其中环碳或环氮可能被取代。
在结构单元E中的UE是氧、硫或NRE 2,优选硫或NRE 2并且特别优选NRE 2
系数h和i分别是0或1。
在优选的实施方案中,系数i是1。
对结构单元E中的RE 1和RE 2来说,支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基或芳基烷基或被取代的或不被取代的芳基、杂芳基或C3-C7-环烷基分别是指例如上述RL 14中所述的相应基团。
对RE 1和RE 2来说,支链或直链的、被取代的或不被取代的CO-C1-C6-烷基、CO-O-C1-C6-烷基、CO-NH-C1-C6-烷氧基烷基、CO-NH-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的CO-O-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、CO-NH-芳基、SO2-芳基、CO-杂芳基、SO2-亚烷基-芳基、SO2-杂芳基或SO2-亚烷基-杂芳基分别是由例如相应的基团CO、COO、CONH或SO2和相应的上述基团组成。
对RE 1或RE 2来说,优选的基团分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基、C2-C6-烯基、C2-C12-炔基或芳基烷基或被取代的或不被取代的杂芳基或C3-C7-环烷基。
对RE 1或RE 2来说,特别优选的基团是氢、甲基、环丙基、烯丙基或炔丙基。
E1是指具有结构式IE1的结构单元:-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4-(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-IE1其中k2、k4、k6是0或1,并且k1、k3、k5、k7是0,1或2。
对RE 3、RE 4、RE 5、RE 6、RE 7、RE 8、RE 9、RE 10来说,支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基分别是指例如上述RL 1中所述的相应基团。
此外,在各种情况下,分别对两个基团RE 3和RE 4或RE 5和RE 6或RE 7和RE 8或RE 9和RE 10来说,可以一起形成3-到7-元的、被取代的或不被取代的饱和的或不饱和的碳环或杂环,其中杂环可以含有至多3个O、N、S中的杂原子。
-(CH2)X-(YE)Z-RE 11是由C0-C4-亚烷基、任选的连接单元YE和RE 11基团组成,其中YE选自于-CO-、-CO-N(Ry 2)-、-N(Ry 2)-CO-、-N(Ry 2)-CO-N(Ry 2*)-、-N(Ry 2)-CO-O-、-O-、-S-、-SO2-、-SO2-N(Ry 2)-、-SO2-O-、-CO-O-、-O-CO-、-O-CO-N(Ry 2)-、-N(Ry 2)-或-N(Ry 2)-SO2-,优选选自于-CO-N(Ry 2)-、-N(Ry 2)-CO-、-O-、-SO2-N(Ry 2)-、-N(Ry 2)-或-N(Ry 2)-SO2-,其中
Ry 2和Ry 2*分别是氢、支链的或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C8-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的杂芳基、杂芳基烷基、芳烷基、C3-C7-环烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、CO-杂芳基或SO2-亚烷基-芳基,优选分别是氢、甲基、环丙基、烯丙基、炔丙基,并且
RE 11是氢、羟基、CN、卤素、支链的或直链的、被取代的或不被取代的C1-C6-烷基、被取代的或不被取代的C3-C7-环烷基、芳基、杂芳基或芳基烷基、被C1-C4-烷基或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基,被取代的或不被取代的C6-C12-双环烷基、C1-C6-亚烷基-C6-C12-双环烷基、C7-C20-三环烷基或C1-C6-亚烷基-C7-C20-三环烷基、或者3-到8-元饱和的或不饱和杂环,它至多被三个相同的或不同的基团取代并且可含有至多三个O、N、S杂原子,其中两个基团可能一起形成稠合的、饱和的或不饱和的或芳香碳环或杂环,该杂环可含有至多3个相同或不同O、N、S杂原子,该环可能会被取代或不被取代,或者另一被取代的或不被取代、饱和的、不饱和的或芳香环可能会稠合到该环上,例如被取代的或不被取代的2-吡啶基、3-吡啶基、4-吡啶基、2-呋喃基、3-呋喃基、2-吡咯基、3-吡咯基、2-噻吩基、3-噻吩基、2-噻唑基、4-噻唑基、5-噻唑基、2-噁唑基、4-噁唑基、5-噁唑基、2-嘧啶基、4-嘧啶基、5-嘧啶基、6-嘧啶基、3-吡唑基、4-吡唑基、5-吡唑基、3-异噻唑基、4-异噻唑基、5-异噻唑基、2-咪唑基、4-咪唑基、5-咪唑基、3-哒嗪基、4-哒嗪基、5-哒嗪基、6-哒嗪基、2-(1,3,4-噻二唑基)、2-(1,3,4)-噁二唑基、3-异噁唑基、4-异噁唑基、5-异噁唑基或三嗪基。
此外RE 11和Ry 2或Ry 2*也可能会一起形成饱和的或不饱和的C3-C7-杂环,该杂环可以含有至多2个其他选自O、S、N中的杂原子。
优选RE 11和Ry 2或Ry 2*一起形成环状胺作为C3-C7-杂环,在这种情况中,基团连接到相同的氮原子上,如N-吡咯烷基、N-哌啶基、N-六氢氮杂基、N-吗啉基或N-哌嗪基,对于含有游离胺质子的杂环例如N-哌嗪基,游离胺质子可能用常规胺保护基团例如甲基、苄基、Boc(叔丁氧羰基)、Z(苯甲氧基羰基)、甲苯磺酰基、-SO2-C1-C4-烷基、-SO2-苯基或-SO2-苄基替换。
对RE 3、RE 4、RE 5、RE 6、RE 7、RE 8、RE 9或RE 10来说,优选的基团分别是氢、支链或直链、被取代的或不被取代的C1-C6-烷基、被取代的或不被取代的芳基或-(CH2)x-(YE)z-RE 11基团。
在结构单元E1的优选实施方案中,相互独立地,RE 3和RE 4或RE 5和RE 6或RE 7和RE 8或RE 9和RE 10中的一个基团是氢或甲基。
在结构单元E1的特别优选的实施方案中,RE 3、RE 4、RE 5、RE 6、RE 7、RE 8、RE 9或RE 10分别是氢或甲基。
LE和TE分别是CO、CO-NRE 12、NRE 12-CO、硫、SO、SO2、SO2-NRE 12、NRE 12-SO2、CS、CS-NRE 12、NRE 12-CS、CS-O、O-CS、CO-O、O-CO、氧、亚乙炔基、CRE 13-O-CRE 14、C(=CRE 13RE 14)、CRE 13=CRE 14、-CRE 13(ORE 15)-CHRE 14-或-CHRE 13-CRE 14(ORE 15)-,优选CO-NRE 12、NRE 12-CO、SO2-NRE12、NRE 12-SO2和氧。
RE 12是氢、支链的或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基或C2-C8-炔基或被取代的或不被取代的C3-C7-环烷基、杂芳基、芳烷基或杂芳烷基,例如在上述RL 1各种情况中所描述的,或者CO-RE 16、COORE 16或SO2-RE 16,优选氢、甲基、烯丙基、炔丙基和环丙基。
对RE 13、RE 14或RE 15来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基或C2-C6-炔基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基分别指例如在上述RL 1中所述的相应基团。
对RE 13或RE 14来说,支链的或直链的、被取代的或不被取代的C1-C4-烷氧基分别指例如上述RA 14中所述的C1-C4-烷氧基。
对RE 13、RE 14或RE 15来说,优选的亚烷基-环烷基分别是例如上述RL 1中所述的C1-C4-亚烷基-C3-C7-环烷基。
对RE 16来说,支链的或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基或C2-C6-炔基或C1-C5-亚烷基-C1-C4-烷氧基,或者被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳基烷基、C1-C4-亚烷基-C3-C7-杂环烷基、C1-C4-亚烷基-C3-C7-杂环烯基或杂芳烷基是指例如在上述RG 4中所述的相应基团。
对QE来说,被取代的或不被取代的4-到11-元单-或多环脂肪烃或芳香烃,它可以含有至多6个双键和至多6个选自N、O、S中的相同或不同杂原子,其中环碳或环氮可能会被取代或不被取代,最好是指被取代的或不被取代的亚芳基,例如被取代的或不被取代的亚苯基或亚萘基、被取代的或不被取代的亚杂芳基例如下列基团:
Figure A0080755400711
以及它们被取代的或稠合的衍生物,或者通式IE 1到IE 11的基团:
Figure A0080755400712
Figure A0080755400721
其中基团可在两个取向构建入。Z6和Z7相互独立地是CH或氮。Z8是氧、硫或NH。Z9是氧、硫或NRE 19。r1,r2,r3和t相互独立地是0,1,2或3。s和u相互独立地是0、1或2。
QE特别优选被取代的或不被取代的亚苯基,基团:
Figure A0080755400722
及其被取代的或稠合的衍生物,或者通式IE 1、IE 2、IE 3、IE 4和IE 7的基团,其中基团可在两取向构建入。
RE 17和RE 18分别是氢、-NO2、-NH2、-CN、-COOH、羟基、卤素、支链的或直链的、被取代的或不被取代的C1-C6-烷基、C1-C4-烷氧基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或者被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳基烷基,每种情况下如上文所述。
RE 19分别是氢、支链的或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C3-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、杂芳基、CO-杂芳基或SO2-亚烷基-芳基,优选是氢或支链的或直链的、被取代的或不被取代的C1-C6-烷基。
优选的结构单元E是由至少一个属于结构单元E的基团的优选基团组成,而其余基团可以广泛变化。
特别优选的结构单元E是由结构单元E的优选基团组成。
优选的结构单元B或者是由优选的结构单元A组成,而E可以广泛变化,或者由优选的结构单元E组成,而A可以广泛变化。
通式I的化合物和用来制备它们的中间体可以有一个或多个不对称被取代的碳原子。该化合物可以是纯对映体或纯的非对映体或其混合物。优选使用对映体纯化合物作为活性物质。
通式I的化合物也可以其他互变体形式存在。
通式I的化合物也可以为生理上可耐受的盐的形式。
通式I的化合物也可以作为前药以这样一种形式存在,以这种形式通式I的化合物可以在生理条件下被释放出来。这里可以以结构单元L中的T基团为例进行说明,在一些情况中它含有能够在生理条件下被水解成游离羧基的基团。这也适用于在生理条件下能够释放结构单元B或A的衍生结构单元B或A。
在通式I的优选化合物中,在各种情况下,三个结构单元B、G或L之一有优选范围,同时其他结构单元可以广泛变化。
在通式I的特别优选的化合物中,在各种情况下,三个结构单元B、G或L中的两个有优选范围,同时其他结构单元可以广泛变化。
在通式I的非常特别优选的化合物中,在各种情况下,所有三个结构单元B、G或L都有优选范围,同时其他结构单元可以广泛变化。
例如通式I优选的化合物含有优选的结构单元G,同时结构单元B和L可以广泛变化。
在通式I特别优选的化合物中,例如B被结构单元A-E-所替代,并且例如化合物含有优选的结构单元G和优选的结构单元A,同时结构单元E和L可以广泛变化。
例如,其它特别优选的化合物含有优选的结构单元G和优选的结构单元A,同时结构单元E和L可以广泛变化。
其中A-E-代表B-的非常特别优选的通式I化合物如下所列,其中在字母块前的数字是通式I的单个化合物的编号,并且在各种情况下用横线分开的A-E-G-L字母块中的缩写分别表示单个结构单元A、E、G或L,并且在表后解释了结构单元缩写。
                                       50  pippy-pyma2-imo-bphabsNo. A-E-G-L                                51  me2py-pymea-oem-zlys
                                       52  imhs-edian2-ocho-psdap1   imhs-m24thizman2-mes-oxal              53  piraz-dis-ocho-osdap2   dmam-ams2-5pho-zlys                    54  me2py-dis-napo-betaet3   pyr-dimephmep-eoco-psdab               55  thpym-diphmep-emo-betapy4   imhs-diphmem-baeo-betadcph             56  thpym-25thiman2-aco-zorn5   imhs-24thizman2-men-zdabs              57  bzl-m24thizman2-ocho-psdap6   piraz-dis-5pho-aspbzla                 58  bzl-pipa-meo-zdab7   pippy-m24thizman2-eoco-betadcph        59  tolhs-edian2-chexo-zdapee8   2py-eta-nol-psdap                      60  piraz-25oxman2-imo-ibsdap9   bim-pazin-oem-zdapee                   61  bim-amn2-5pho-betapy10  chmhs-dimephmep-5pho-psdap             62  bimhs-mepazin-meo-aspibua11  2py-mepipen2-imo-zdabs                 63  2py-pazin-5pho-bsdap12  bimhs-m24thiman2-hso-zdap              64  amim-ams2-meto-aspibua13  pippy-din-meo-bsdap                    65  bhs-diphmem-emo-bsdap14  2py-mepipe-meo-psdab                   66  morhs-pazin-eoco-bhsdab15  2py-m25thiz-meo-betapy                 67  phhs-dis-fo-mezphe16  amim-dis-ocho-osdap                    68  am2py-mepipen2-oeto-aspaba17  imhs-dimephmep-5amo-aspbzla            69  me2py-2pazin-fo-zdab18  me2py-eta-meo-mezphe                   70  chmhs-pipmea-napo-asppha19  bzl-pazin-men-mezphe                   71  piraz-eta2s-5pho-bhsdap20  dpam-mepipe2-sem-nbetabnaphth          72  pippy-pazi2n-hso-csdap21  2py-25oxman2-emo-aspibua               73  pippy-tetradi-meo-betadcph22  2pmhs-din-paco-psdab                   74  am2py-pyma2-5amo-aspbzla23  mam2py-dimephmep-pyo-dfzdap            75  2py-edia2-sem-nbetabnaphth24  mam2py-m24thiz-no2-aspibua             76  amim-mepipe2-sem-nzdap25  imhs-thizn-men-betadcph                77  bim-amn3-fo-zlys26  phpip-din-no2-betapy                   78  mam2py-amn2-5amo-bphabs27  tolhs-mepipe-mmen-betadcph             79  dmam-ams2-cnmo-zdabs28  mam2py-dis-no2-psdab                   80  thpym-mepipe-4amo-zlys29  amim-pazin-meteto-oxal                 81  impy-24thiz-mmen-thizzdap30  bim-pazin-no1-zdap                     82  bhs-edian2-oem-bnsdap31  impy-pyma2-chexo-betainyl              83  4pmhs-edia2-oem-nbetameph32  mam2py-trias-eoco-aspibua              84  hythpym-24thiz-meo-zlys33  imhs-diphmem-imo-csdap                 85  bhs-pazin-oem-bhsdap34  imhs-props-chexo-bhsdab                86  piraz-25oxman2-no1-oxal35  ec-diaz-emo-bsdap                      87  im-pipa-ocho-betapy36  mam2py-tetradi-oem-bsdap               88  im-mea2s-napo-csdap37  imhs-diphmem-5pho-csdap                89  imhs-amn2-meo-bnsdap38  thpym-mepazin-eoco-asppha              90  2py-tridi-5amo-bsdap39  bimhs-m25thiman2-men-dfzdap            91  pippy-m24thizman2-oem-bhsdap40  me2py-diphmep-fo-bphabs                92  im-pnymea-5pho-asppha41  ibhs-pazin-ocho-bphabs                 93  mam2py-m24thizman2-no2-ppsdap42  bhs-pipmea-ocho-tsdap                  94  chmhs-thizn-napo-psdapee43  morhs-diphmem-cnmo-betadcph            95  amim-diphmep-5amo-bhsdap44  ppy-dimen-oem-betainyl                 96  amim-amn3-napo-betainyl45  impy-din-no1-aspibua                   97  morhs-amn3-ocho-zlys46  menim-ams2-eoco-zdab                   98  am2py-tetradi-eoco-zdabs47  mam2py-amo3-baeo-glupha                99  amim-25thizman2-napo-aspbzla48  bhs-edian2-no2-psdab                   100 bim-m24oxman2-mmen-zdabs49  am4py-am2-sem-nbeta34dimeoph           101 imhs-24thizman2-emo-asppha102  bim-25oxman2-mecpo-glyzdap         154  imhs-pazin-ocho-bsdap103  thpym-mepipe-meo-zdap              155  dmam-pipa-mecpo-betainyl104  mam2py-pyma2-meto-bhsdab           156  me2py-24thiz-oem-betapy105  am-25thizman2-napo-zdab            157  bim-pyma2-mes-dfzdap106  piraz-24thiz-baeo-psdab            158  mam2py-pipmeo-5amo-bhsdab107  ibhs-propa2s-5amo-glubzla          159  amim-am3diaz-cnmo-aspbzla108  cl3pyme-diphmem-chexo-betaet       160  am2py-amn3-oem-ppsdap109  2py-edian2-eoco-bnsdap             161  edothpym-dis-meto-bphabs110  prhs-dimephmep-no2-zdap            162  amthiaz-dimephmem-eoco-111  amthiaz-pipmea-emo-glyzdap              betainyl112  me2py-mepipe-eoco-bnsdap           163  2py-m25thiz-mes-aspbzla113  amim-diphmem-meo-bhsdab            164  piraz-trias-napo-zdab114  dmam-amn3-mes-betainyl             165  mepip-pymea-no1-psdab115  piraz-dimephmep-ocho-zlys          166  pippy-tridi-no2-betadcph116  im-2pazin-mes-bphabs               167  bhs-edian2-no2-bhsdap117  impy-ams2-napo-tsdap               168  pyraz-din-meo-betapy118  piraz-pipa-5amo-betaet             169  pyraz-dimen-paco-bsdap119  bzl-edia2-oem-npsdap               170  chhs-mepipe-fo-mezphe120  bhs-mepipe-no2-psdap               171  hythpym-tetradi-ocho-betainyl121  hythpym-24thiman-napo-aspibua      172  dhim-24thizman2-pro-bnsdap122  hythpym-dich-mes-psdab             173  me2py-amn3-napo-aspbzla123  gua-24thizman2-imo-aspibua         174  am2py-mepipe-5pho-bnsdap124  imhs-din-pro-csdap                 175  amim-ams2-no2-betapy125  bhs-pymea-meo-aspibua              176  mam2py-dich-oem-betapy126  me2py-24thiz-fo-bhsdap             177  imhs-25thiz-pheo-glyzdap127  dhim-eta-emo-betapy                178  thpym-amn2-mes-zdab128  hythpym-am3-sem-nzdab              179  nmhs-amn2-mmen-asppha129  phhs-dimephmep-oem-tsdap           180  dmam-tetradi-imo-glubzla130  bim-tetradi-chexo-zlys             181  me2py-24thizman2-ocho-bhsdap131  bimhs-pnymea-ocho-zdap             182  bhs-pazin-ocho-zdab132  thpym-dimephmem-men-betaet         183  dmbim-pnymea-no2-mezphe133  bhs-dimen-chexo-betadcph           184  hythpym-pnymea-5pho-csdap134  imhs-n2nme2n-hso-zlys              185  dhim-pnymea-meto-zlys135  2pmhs-am2-oem-nbeta34dimeoph       186  bim-tetradi-cpro-osdap136  deam-dis-5amo-aspibua              187  cl3pyme-mepipen2-meo-aspbzla137  bhs-edian2-no2-bphabs              188  am4py-pentadi-mes-zdapee138  2py-mepipe-eoco-zdap               189  impy-m25thiz-mes-zdab139  me2py-m24oxman2-5amo-bphabs        190  prhs-thizo-aco-betadcph140  impy-mepazin-emo-betaet            191  piraz-m25thiz-oem-bsdap141  tolhs-edia2-sem-nbeta34dimeoph     192  pippy-n2o2n-mmen-psdap142  bim-eta-no2-psdap                  193  tolhs-amo2-meo-glupha143  im-pipmes-cpeo-zdap                194  impy-butn-pheo-csdap144  pyraz-n2o2n-ocho-aspibua           195  thpym-25oxman2-men-aspibua145  amim-pipa-mecpo-zdap               196  bim-edian2-mes-bnsdap146  bhs-am2-oem-npsdap                 197  amim-tetradi-eoco-aspbzla147  deam-edian2-mes-psdap              198  tolhs-m25oxman2-4amo-aspbzla148  me2py-eta2s-meo-bhsdab             199  im-m24thiman2-chexo-zdap149  bimhs-25thiz-cpro-aspibua          200  me2py-amo2-mes-bhsdap150  hythpym-amn3-eoco-asppha           201  am2py-mepipen2-5pho-psdab151  bhs-tetradi-4amo-zdabs             202  piraz-edian2-eoco-zdap152  2py-dimephmem-chexo-glyzdap        203  dhim-pipa-meo-aspibua153  bimhs-ams2-imo-ibsdap              204  ec-eta2s-ocho-glyzdap205  hythpym-am3-sem-nzdab                257  bhs-thizn-cno-bsdap206  pippy-24oxman2-imo-bhsdap            258  amim-tetradi-napo-aspaba207  pippy-24thizman2-emo-betadcph        259  am4py-din-oem-zdap208  bzl-din-fo-betapy                    260  deam-24thiz-cpro-mezphe209  imhs-diphmep-men-asppha              261  thpym-pazin-eoco-bsdap210  thpym-edian2-no1-psdab               262  piraz-pyma2-no2-bhsdap211  impy-mepipen2-napo-glupha            263  me2py-24thiman2-meo-bhsdab212  moegua-mepipe-pro-bhsdab             264  2py-mepazin-mes-psdab213  hythpym-amn3-chexo-bhsdab            265  mam2py-mepipe2-oem-nbetapy214  piraz-eta-no1-betapy                 266  imhs-24thiman-fo-betapy215  imhs-ams2-eoco-csdap                 267  bim-eta-mes-betapy216  hythpym-mepipe-aco-aval              268  bim-24thiz-meto-bhsdap217  bim-amn2-no1-zdap                    269  thpym-pazin-no2-zdab218  bzl-pnymea-imo-bhsdap                270  mam2py-dimephmep-mes-betadcph219  thpym-edian2-ocho-psdab              271  2py-amn3-men-glyzdap220  bhs-m24thizman2-5amo-csdap           272  bimhs-diaz-no2-zdapee221  bz-dimephmem-4pho-aval               273  pippy-amn3-men-psdab222  dhim-25thiz-hso-aspibua              274  impy-pyma2-imo-aspibua223  2py-edian2-eoco-bsdap                275  bimhs-pipmeo-fo-bhsdap224  thpym-pazin-no1-betapy               276  am4py-tridi-daco-ibsdap225  bhs-m24thiz-daco-mezphe              277  thpym-mepipe-ocho-zdab226  bim-edian2-meo-zdab                  278  hythpym-eta2s-5pho-dfzdap227  emnim-pymea-mes-bphabs               279  chmhs-amn2-men-mezphe228  impy-mea-meo-ibsdap                  280  thpym-pipa-4pho-zdap229  impy-dimen-mes-mezphe                281  pippy-pymea-4pho-betapy230  imhs-amn2-mes-zdab                   282  thpym-mepipe-ocho-glupha231  piraz-diaz-cno-betainyl              283  impy-24thizman2-mes-mezphe232  impy-m24thizman2-emo-bsdap           284  bimhs-tridi-eoco-aspibua233  amim-24thiz-meo-bhsdap               285  bimhs-dis-mes-bphabs234  am2py-mepipe-5amo-bnsdap             286  bhs-am3diaz-5amo-mezphe235  amim-trias-paco-psdap                287  cl3pyme-amn3-daco-psdapee236  imhs-edian2-mes-bsdap                288  bhs-pipmea-cpro-asppha237  bim-dis-emo-asppha                   289  amim-pnymea-oem-bhsdap238  bim-24thiman2-5pho-aspibua           290  bhs-edian2-no2-zdab239  bhs-edian2-oem-psdab                 291  bz-eta-emo-aspbzla240  2py-pyma2-chexo-psdapee              292  dpam-dio-eoco-bhsdab241  emnim-am2-oem-nbeta34dimeoph         293  imhs-24thizman2-cno-aspibua242  pippy-m25thiz-meo-dfzdap             294  piraz-trias-meo-zlys243  am2py-amo2-napo-bhsdap               295  ibhs-pipa-meto-csdap244  deam-am3-oem-npsdap                  296  ec-am3diaz-ocho-dfzdap245  2pmhs-pymea-ocho-bhsdap              297  bhs-mepazin-meo-betadcph246  thpym-dipch-chexo-glyzdap            298  pyraz-pipmea-mes-psdap247  bim-mepipe-ocho-betapy               299  me2py-amo2-mes-asppha248  dhim-pipa-aco-zdabs                  300  tolhs-am2-sem-nbeta34dimeoph249  am2py-ams2-5pho-zdap                 301  bhs-amn3-imo-osdap250  bim-propn-eoco-aspibua               302  n2py-dimephmem-pro-betainyl251  imhs-ams2-men-aspbzla                303  bhs-trias-napo-dfzdap252  piraz-pymea-chexo-csdap              304  thpym-dimen-men-dfzdap253  tolhs-mepazin-oeto-zdab              305  thpym-thizn-cpeo-ibsdap254  bim-diphmep-5amo-bsdap               306  imhs-eta-chexo-tsdap255  bimhs-propa2s-cpeo-csdap             307  piraz-thizn-paco-glyzdap256  thpym-pazin-no2-bhsdap               308  pyraz-diphmep-5amo-aval309  piraz-pyma2-napo-betadcph            361  dmbim-eta-fo-asppha310  2py-pipmea-eoco-zdap                 362  amim-amn2-mes-thizzdap311  bhs-mepipe-meo-psdab                 363  mepip-pazi2n-5pho-betapy312  piraz-trias-emo-bhsdap               364  bim-mepipe-oem-bnsdap313  amim-edia2-oem-nbeta34dimeoph        365  imhs-eta-5pho-zdab314  nmor-mepazin-no1-bhsdab              366  me2py-am3-oem-npsdap315  impy-mepipe-chexo-bphabs             367  pippy-tetradi-imo-glyzdap316  dmam-am3diaz-no1-glyzdap             368  thpym-m24thizman2-oem-dfzdap317  bim-mepipe-meo-bsdap                 369  piraz-pipmea-cpro-betapy318  piraz-mepazin-chexo-psdap            370  deam-mepipe-cpeo-bnsdap319  moegua-mepazin-fo-csdap              371  dhim-25oxman2-napo-psdab320  imhs-25thiman2-eoco-bphabs           372  amim-n2nme2n-5amo-bsdap321  me2py-m25thiz-chexo-zorn             373  prhs-24thizman2-mommo-csdap322  mam2py-tridi-men-mezphe              374  2py-edia2-oem-nbetapy323  morhs-am3-oem-nbetameph              375  bimhs-din-meo-bhsdab324  pyrhs-m25thiz-oem-glupha             376  chhs-pyma2-ocho-betapy325  me2py-pnymea-mes-betainyl            377  2py-amn3-5pho-psdab326  mam2py-amo2-no1-zdab                 378  thpym-eta-5pho-bhsdap327  2py-mepipe-mes-bsdap                 379  piraz-pyma2-meo-psdab328  impy-diphmep-ocho-asppha             380  chhs-thizn-fo-betainyl329  nmor-hexas-chexo-psdap               381  pippy-m25thiz-chexo-zorn330  me2py-pipmea-ocho-asppha             382  fthpym-pnymea-oem-bnsdap331  imhs-pazin-no1-psdap                 383  bhs-24thizman2-no2-bphabs332  2py-mepipe-5pho-zdab                 384  pippy-edian2-chexo-psdab333  fthpym-am3-sem-nbetabnaphth          385  imhs-amn2-no2-betapy334  bhs-amn2-oem-psdap                   386  2py-25thiz-no1-aval335  piraz-pazi2n-ocho-aspibua            387  impy-pymea-peo-aspbzla336  emnim-24thizman2-imo-bhsdab          388  pyraz-tridi-cpro-bphabs337  nim-diphmem-oem-zdab                 389  me2py-din-imo-bhsdab338  2py-ms-mes-zdap                      390  phhs-hexadi-5amo-psdap339  2py-edian2-ocho-bsdap                391  mepip-m25thiz-ocho-zdabs340  nmor-diphmep-no1-bsdap               392  imhs-amn2-5pho-bhsdap341  amim-25oxman2-nmo-betadcph           393  bhs-m25thiz-fo-ppsdap342  mam2py-edian2-5pho-osdap             394  dhim-edian2-imo-bsdap343  pyr-n2o2n-cno-betapy                 395  me2py-dimen-aco-zorn344  phpip-pipmes-fo-mezphe               396  2py-eta-oem-zdapee345  bhs-24thiz-mes-psdab                 397  cl3pyme-25oxman2-5amo-bphabs346  fthpym-eta-mes-dfzdap                398  phpip-edian2-fo-psdap347  bhs-edian2-ocho-psdap                399  am2py-trias-oem-psdapee348  ibhs-mepipe-emo-bhsdap               400  nmhs-3pazin-imo-dfzdap349  edothpym-pipa-pro-zdap               401  thpym-dimen-napo-bhsdab350  bzl-am2-sem-npsdap                   402  amim-24thizman2-meo-psdab351  pippy-dimephmep-emo-bphabs           403  bim-dipch-eoco-zdabs352  mam2py-pipmea-napo-bnsdap            404  ppy-m25thiz-no1-aspbzla353  me2py-dimephmem-mes-betapy           405  ec-eta-meo-aspibua354  imhs-24thizman2-no2-asppha           406  thpym-pipa-oeto-mezphe355  am4py-n2nme2n-no2-bhsdap             407  2py-tetras-no2-csdap356  mam2py-tetradi-no2-dfzdap            408  2py-25oxman2-cno-psdap357  imhs-dis-meo-zdabs                   409  chhs-pipmeo-oem-betadcph358  bimhs-propa2s-oem-asppha             410  bzl-eta-fo-mezphe359  chmhs-24thiz-napo-glyzdap            411  bim-pazin-no1-bnsdap360  me2py-edian2-5amo-aspbzla            412  nim-am3-oem-nzdab413  bim-dimen-eoco-zdabs                 464  bhs-pazin-no1-bhsdap414  bhs-amn2-5pho-zdab                   465  thpym-mepipe-5pho-bsdap415  mepip-pymea-emo-zdap                 466  2py-pnymea-ocho-aspbzla416  am2py-pipmea-fo-zdab                 467  pyraz-pazin-fo-aspbzla417  hythpym-diphmem-pheo-zdap            468  nmor-pymea-men-zdabs418  piraz-ams2-5pho-zdabs                469  gua-amo3-oeto-mezphe419  impy-edia2-sem-nbetabnaphth          470  bzl-mepazin-hso-aspibua420  thpym-eta-meo-mezphe                 471  amim-mepazin-baeo-zdab421  prhs-m25thiz-meo-dfzdap              472  mam2py-24thizman2-cno-glubzla422  bhs-pazin-mes-zdab                   473  bimhs-amn3-ocho-aspbzla423  am2py-thizn-4amo-bphabs              474  hythpym-dimephmep-no2-csdap424  am2py-dio-no1-psdap                  475  pippy-pipa-cno-mezphe425  gua-mepipen2-no2-thizzdap            476  dhim-pymea-mecpo-aval426  am-dimen-5pho-glubzla                477  piraz-pnymea-oem-glyzdap427  nim-amn3-paco-zdabs                  478  2py-amn2-ocho-bhsdap428  moegua-eta-chexo-bhsdab              479  ibhs-24thiz-meteto-bsdap429  dhim-pymea-chexo-zdabs               480  cl3pyme-am2-sem-nbeta34dimeoph430  amim-edia2-sem-nbetameph             481  phhs-edian2-fo-zdap431  piraz-pazin-baeo-aspbzla             482  nim-m24thizman2-men-osdap432  nmhs-24thizman2-5amo-bhsdap          483  dhim-dimen-imo-csdap433  bim-dis-imo-betainyl                 484  bim-din-emo-zdap434  amim-mepipen2-fo-csdap               485  phpip-dimephmep-pyo-zdabs435  piraz-pyma2-fo-dfzdap                486  impy-amn3-meo-zdab436  pippy-thizo-no2-betapy               487  imhs-amn2-oem-psdap437  2py-pipmea-chexo-osdap               488  2py-dimephmep-men-glyzdap438  impy-dipch-no1-zdabs                 489  phpip-pymea-oeto-mezphe439  chmhs-trias-paco-asppha              490  tolhs-eta-eoco-aspibua440  mepip-diphmem-fo-betainyl            491  me2py-mepipe-imo-psdap441  me2py-dich-eoco-dfzdap               492  emnim-mepazin-napo-zdab442  bhs-dimen-ocho-aspibua               493  2pmhs-amn3-oem-psdab443  bzl-edian2-aco-betainyl              494  edothpym-24thiman-meteto-psdap444  im-eta-aco-bhsdap                    495  thpym-dimen-mes-dfzdap445  dmthpym-mepipen2-pro-aspbzla         496  thpym-tetradi-chexo-aspibua446  bim-props-no1-asppha                 497  bhs-thizn-no2-bhsdab447  impy-24thizman2-5pho-zdabs           498  mam2py-tridi-fo-betadcph448  bz-am2-oem-nbetapy                   499  thpym-dimen-mes-csdap449  npip-m24thiman2-chexo-bhsdab         500  am2py-24thizman2-oem-ppsdap450  2py-diphmem-chexo-psdab              501  am2py-dimen-oem-bsdap451  prhs-25thizman2-no2-betadcph         502  bimhs-pymea-pheo-bhsdab452  piraz-pymea-napo-psdap               503  imhs-amn2-imo-psdab453  amim-edian2-5pho-betapy              504  me2py-mepipe-4amo-betainyl454  hythpym-m25thiman2-chexo-            505  mam2py-m25thiz-imo-psdap
 glubzla                              506  mam2py-m24thizman2-oem-bhsdab455  ec-amn2-mmen-bsdap                   507  hythpym-pyma2-fo-psdap456  impy-pazin-5pho-betapy               508  impy-trias-fo-bsdap457  am2py-amo2-fo-bhsdap                 509  nim-diphmep-cnmo-betainyl458  dhim-edian2-aco-dfzdap               510  mam2py-diphmem-no1-bhsdap459  mam2py-dis-no2-bnsdap                511  phhs-pazin-oem-betaet460  2py-eta-ocho-bhsdap                  512  edothpym-butn-5pho-zdab461  imhs-amn3-5pho-psdap                 513  thpym-eta-mes-zdab462  emnim-m25thiz-mes-bsdap              514  impy-tridi-no2-dfzdap463  ibhs-edia2-oem-npsdap                515  piraz-dimephmem-nmo-aspibua516  dhim-dimephmep-oem-bhsdap             568  me-mepazin-oeto-bphabs517  bhs-pazin-baeo-zdabs                  569  am2py-dimephmep-eoco-betainyl518  imhs-amn2-ocho-psdab                  570  nim-props-meto-aspbzla519  bhs-dimen-no2-betadcph                571  me2py-pipmea-5pho-mezphe520  bim-thizn-paco-bhsdab                 572  piraz-mepipe-5pho-mezphe521  gua-am3-sem-nzdab                     573  hythpym-trias-cpro-psdap522  pippy-pymea-meto-betainyl             574  bhs-dio-imo-mezphe523  prhs-thizn-napo-betapy                575  pyr-trias-5pho-aspibua524  2py-dis-imo-zdap                      576  dpam-25thizman2-meo-aval525  fthpym-3pazin-meto-aspbzla            577  bim-pazin-ocho-bnsdap526  piraz-24thiman-5amo-betainyl          578  pippy-eta-fo-asppha527  pippy-tetradi-men-csdap               579  dhim-24oxman2-men-aspibua528  morhs-dimephmem-oem-betainyl          580  dmam-dis-baeo-zdap529  dhim-am3-sem-nbetameph                581  n2py-din-mes-bphabs530  thpym-mepipe-eoco-zdap                582  am2py-24thizman2-chexo-zdab531  bim-24thiman-oem-mezphe               583  bim-eta-meo-zdab532  fthpym-thizn-pheo-betainyl            584  phpip-mea2s-meto-bhsdap533  bhs-ams2-ocho-bhsdab                  585  bzl-m24thizman2-5amo-glubzla534  bhs-din-emo-aspbzla                   586  ibhs-25thizman2-baeo-betainyl535  bimhs-24thiman-eoco-bnsdap            587  me2py-m24thizman2-eoco-zdab536  chhs-din-men-glupha                   588  chmhs-pazin-pheo-aspibua537  phpip-24thizman2-mecpo-bhsdab         589  impy-diphmem-4pho-bnsdap538  piraz-edian2-5amo-bsdap               590  piraz-m25thiz-peo-bnsdap539  bim-dimen-mes-betaet                  591  hythpym-25thiman2-no2-ppsdap540  thpym-edian2-no2-bnsdap               592  im-pnymea-paco-dfzdap541  deam-diphmem-chexo-bhsdab             593  impy-eta-mommo-bnsdap542  bimhs-mepipen2-hso-betapy             594  bim-edia2-oem-nbetabnaphth543  thpym-am3-sem-nzdap                   595  thpym-m24thizman2-chexo-mezphe544  dhim-tetradi-imo-zdabs                596  mam2py-thizn-imo-glubzla545  piraz-ams2-5pho-psdap                 597  pippy-dimen-mes-betapy546  bhs-amn2-oem-zdap                     598  bim-amn2-ocho-bnsdap547  hythpym-tridi-mmen-psdab              599  z-edia2-oem-nbetapy548  pyraz-amn2-fo-mezphe                  600  ec-m25thiz-5pho-betainyl549  2py-am2-oem-nbetameph                 601  thpym-edian2-no2-betapy550  dmbim-mepipe-chexo-betaet             602  me-diphmem-5pho-betadcph551  hythpym-eta-fo-bsdap                  603  thpym-trias-imo-dfzdap552  dhim-mepipe2-sem-nbetameph            604  me2py-n2nme2n-fo-bphabs553  2py-amn2-5pho-zdab                    605  bimhs-amn2-5pho-mezphe554  hythpym-trias-ocho-osdap              606  imhs-eta-meo-asppha555  bimhs-pyma2-napo-glyzdap              607  impy-m24thizman2-meo-bnsdap556  dpam-mepipen2-meo-aspbzla             608  z-amn3-no1-bphabs557  am4py-24thizman2-eoco-osdap           609  am-24thiz-5amo-glyzdap558  bim-edian2-eoco-bhsdap                610  dhim-tridi-oem-zdab559  thpym-eta-ocho-zdab                   611  dhim-dis-aco-ibsdap560  2py-pnymea-no2-aspibua                612  npip-pyma2-imo-zorn561  hythpym-pyma2-emo-betadcph            613  chhs-pnymea-5amo-zdabs562  imhs-amn3-cno-aspbzla                 614  nim-pnymea-4pho-psdab563  imhs-mepipe-eoco-bsdap                615  bim-pazi2n-cnmo-betadcph564  imhs-pyma2-no1-psdap                  616  hythpym-pipmea-emo-bhsdab565  moegua-m24thizman2-ocho-zdab          617  pyr-pipa-paco-betainyl566  bz-pymea-napo-betadcph                618  bim-pipa-no1-ppsdap567  npip-pyma2-eoco-zorn                  619  n2py-dimephmem-ocho-zdapee620  2py-am3-oem-npsdap                    671  bhs-25thiz-men-glyzdap621  thpym-edian2-eoco-bphabs              672  thpym-ams2-pyo-aspbzla622  ppy-m25thiz-5amo-bhsdab               673  2py-m24thizman2-4pho-psdap623  dhim-pipmea-mecpo-bnsdap              674  thpym-pazin-meo-psdap624  tolhs-am3diaz-imo-zdabs               675  me2py-amo3-meo-glyzdap625  n2py-pnymea-men-glyzdap               676  me2py-mepazin-4pho-bsdap626  imhs-25oxman2-imo-aspbzla             677  am2py-dimephmep-men-zdab627  me2py-amn2-baeo-aspibua               678  cl3pyme-mepipe-4amo-bhsdap628  hythpym-mepipe2-sem-nbeta34-          679  me2py-pentas-5pho-psdab
 dimeoph                               680  imhs-eta-imo-mezphe629  moegua-m25thiz-cpro-zdap              681  ibhs-m24thiman2-4pho-glubzla630  thpym-edian2-meo-psdab                682  amim-pipmea-ocho-glupha631  impy-pymea-meto-bphabs                683  emnim-diphmem-peo-psdap632  imhs-edian2-oem-betapy                684  pippy-eta-aco-bnsdap633  2py-pyma2-5amo-zdabs                  685  imhs-mepipe-5pho-aspibua634  thpym-tridi-meo-aspibua               686  bim-pipa-oem-bhsdab635  bhs-pnymea-no2-betainyl               687  bhs-amn2-meo-zdap636  dhim-mepipe-chexo-aspibua             688  pippy-mepipe2-sem-nbetabnaphth637  hythpym-mepipen2-men-betainyl         689  dmbim-dimen-cnmo-betadcph638  2py-ms-pro-betadcph                   690  z-m24thizman2-napo-bphabs639  bhs-m25thiz-daco-zdap                 691  bim-m24thizman2-baeo-betapy640  mam2py-amo3-fo-aspibua                692  thpym-am2-sem-nbetabnaphth641  dmam-25oxman2-fo-zdap                 693  ec-indan2-napo-bhsdab642  hythpym-ams2-napo-bhsdab              694  bhs-pymea-meo-dfzdap643  bhs-amn3-hso-psdab                    695  hythpym-tetradi-no2-zdap644  me2py-indan2-eoco-bphabs              696  piraz-ams2-5pho-glubzla645  bim-amn2-eoco-psdab                   697  pyrhs-24thiz-eoco-aspibua646  thpym-m24thizman2-ocho-psdap          698  bim-m24thizman2-5pho-betainyl647  me2py-m25thiman2-no1-zlys             699  cl3pyme-pentas-daco-asppha648  2py-m24thizman2-no1-bphabs            700  dhim-25oxman2-no2-bphabs649  dhim-tridi-chexo-bnsdap               701  thpym-pazin-emo-zdab650  amim-pipmeo-5pho-aspibua              702  phpip-24thiz-napo-psdap651  pippy-24thizman2-nmo-betadcph         703  4pmhs-m25thiman2-4amo-bsdap652  pippy-propn-5pho-betadcph             704  am2py-props-mes-bhsdab653  nmor-m25thiman2-mes-zdabs             705  morhs-trias-mecpo-zdap654  ppy-propa2s-baeo-psdap                706  dhim-n24thiman-cpeo-betainyl655  bhs-mepipen2-meo-dfzdap               707  z-edia2-sem-nbetabnaphth656  bhs-edian2-eoco-zdap                  708  dhim-dimephmem-eoco-aspibua657  2py-amn2-oem-bsdap                    709  deam-diphmep-5amo-bphabs658  morhs-amo2-ocho-psdap                 710  mam2py-amn2-imo-ibsdap659  nmhs-dis-no2-bhsdap                   711  2py-2pazin-peo-betapy660  am2py-am3-sem-nbetameph               712  thpym-m24thiz-cpeo-glupha661  hythpym-n2nme2n-men-psdab             713  bimhs-mepipe-5pho-zdabs662  bim-pyma2-no2-bphabs                  714  piraz-dimen-imo-asppha663  imhs-eta-mes-bsdap                    715  bim-dich-meo-bnsdap664  me2py-mepipen2-5amo-mezphe            716  tolhs-am3-oem-nbetapy665  amim-am2-sem-npsdap                   717  bimhs-25oxman2-eoco-thizzdap666  ibhs-thizn-ocho-psdab                 718  pyraz-pentadi-no1-zlys667  phpip-pazin-men-csdap                 719  bim-3diaz-oem-betainyl668  dmam-25oxman2-oem-glyzdap             720  piraz-amn2-no2-aval669  thpym-eta-5pho-zdab                   721  bimhs-amo3-cpro-mezphe670  2pmhs-pyma2-5amo-betadcph             722  pyrhs-amn3-4pho-bhsdab723  imhs-pazin-oem-zdap                   775  ibhs-dich-eoco-zdab724  dpam-edian2-imo-zdabs                 776  amim-am3-oem-nbetameph725  bim-25oxman2-chexo-zorn               777  fthpym-pipa-men-zdap726  am2py-ams2-chexo-bphabs               778  edothpym-pyma2-ocho-mezphe727  2py-mepipe-hso-asppha                 779  imhs-pipmea-imo-psdap728  imhs-dis-meteto-bnsdap                780  amthiaz-pyma2-imo-betapy729  imhs-pazin-5pho-psdap                 781  thpym-mepipe-mes-psdap730  piraz-dimephmep-no2-zorn              782  amthiaz-am2-sem-nbeta34dimeoph731  thpym-butn-mes-aspibua                783  bhs-diphmem-chexo-mezphe732  phpip-tetradi-4pho-psdap              784  am2py-pipmea-pro-bsdap733  me2py-pnymea-napo-mezphe              785  ibhs-amn3-fo-asppha734  bz-pymea-mes-dfzdap                   786  dmam-amn3-5amo-psdab735  pippy-amn3-napo-betadcph              787  nmhs-24thiz-oem-aspibua736  am4py-diphmem-mommo-bsdap             788  nmor-dis-napo-psdap737  hythpym-edian2-no2-betapy             789  nmor-mepazin-4pho-glubzla738  imhs-edian2-5pho-psdab                790  morhs-tetradi-emo-betapy739  mam2py-m24thizman2-fo-betainyl        791  hythpym-dimephmep-mommo-bnsdap740  bhs-tridi-5pho-psdap                  792  me2py-pymea-men-ibsdap741  bimhs-n2nme2n-emo-bhsdap              793  thpym-mepipe-no1-bnsdap742  bim-dimen-oem-betaet                  794  am2py-pymea-fo-csdap743  mam2py-amo2-oem-asppha                795  2py-diphmem-imo-aspibua744  pippy-eta-4pho-aval                   796  ibhs-trias-men-bhsdap745  pyrhs-m25thiman2-oem-glyzdap          797  mam2py-dimephmep-pro-aspibua746  hythpym-mepipe-chexo-mezphe           798  bim-pazin-mes-psdab747  am4py-pyma2-imo-bnsdap                799  dpam-tridi-ocho-bsdap748  pippy-edian2-eoco-bhsdap              800  dhim-24thiz-5amo-bhsdap749  piraz-am2-oem-nbeta34dimeoph          801  2py-edian2-mes-zdap750  dpam-am3-oem-nzdap                    802  2pmhs-dimephmem-napo-aspbzla751  amim-24thiz-no1-bphabs                803  piraz-tridi-fo-betainyl752  bhs-m25thiz-pheo-zdap                 804  bim-24thizman2-5pho-zdab753  bhs-eta-fo-betadcph                   805  bhs-diaz-oem-betainyl754  hythpym-dipch-5amo-aspbzla            806  thpym-pyma2-oem-bsdap755  4pmhs-tetras-no2-ppsdap               807  imhs-eta-mes-zdap756  am2py-hexas-meto-dfzdap               808  2py-mepipe-mes-betapy757  amim-24thizman2-pyo-bsdap             809  bim-pymea-chexo-zdap758  tolhs-mepipen2-fo-zdapee              810  ibhs-dis-oem-betadcph759  thpym-m24thizman2-imo-bhsdab          811  pyrhs-pipa-5amo-aspbzla760  npip-m25thiz-hso-betadcph             812  dhim-dimen-meo-betapy761  chhs-mepipe-mes-glyzdap               813  nmor-pipa-chexo-aspibua762  gua-edian2-eoco-aspibua               814  bhs-m24oxman2-fo-betapy763  z-amn3-no2-aspibua                    815  piraz-m24thizman2-5amo-764  pippy-dimephmep-fo-bsdap                   betadcph765  dhim-m25thiman2-meo-tsdap             816  ec-25oxman2-cno-glubzla766  hythpym-trias-eoco-zorn               817  bhs-diphmep-men-betadcph767  im-25oxman2-emo-oxal                  818  impy-diphmep-mes-betainyl768  imhs-dipch-oem-aspbzla                819  pippy-pazin-napo-asppha769  hythpym-tridi-chexo-zdabs             820  bim-eta-5pho-oxal770  bhs-amn2-chexo-zdabs                  821  pippy-amo2-aco-ppsdap771  bimhs-mepipe-napo-tsdap               822  bzl-eta-mes-aval772  imhs-mepipe-meo-psdab                 823  am2py-amo2-men-bsdap773  bim-mepipe-napo-betadcph              824  dhim-25oxman2-napo-zdap774  piraz-m25thizman2-mes-betapy          825  dmthpym-hexadi-mes-bsdap826  nmor-amn3-oem-bhsdap                 878  impy-butn-ocho-psdap827  thpym-pazin-meo-bhsdap               879  bhs-pazin-no1-betapy828  pippy-24thiz-oem-zorn                880  bhs-amn3-men-betainyl829  2py-24thizman2-chexo-mezphe          881  impy-dimen-imo-zdabs830  imhs-mepipe-eoco-psdab               882  piraz-amn3-mmen-psdap831  ec-25oxman2-men-zorn                 883  2py-amn2-mommo-betadcph832  thpym-m24thiz-chexo-bhsdab           884  me2py-din-meo-glyzdap833  2py-mepipe-oem-bsdap                 885  2py-mepazin-fo-ibsdap834  impy-amn2-no2-psdapee                886  imhs-pentadi-5pho-aspibua835  gua-pnymea-fo-mezphe                 887  dmam-m25thiz-meo-betapy836  dmam-24thizman2-daco-csdap           888  bim-edia2-oem-nbetameph837  bhs-amn2-ocho-bsdap                  889  bim-amo2-eoco-aspbzla838  thpym-diphmem-5pho-bnsdap            890  bhs-m24thizman2-mommo-csdap839  me2py-trias-no2-aspibua              891  bim-pipmea-nmo-bhsdap840  z-pyma2-mmen-csdap                   892  impy-pipa-mes-betainyl841  npip-indan2-napo-zdabs               893  impy-24thiz-men-zdap842  am2py-pyma2-daco-betapy              894  im-dich-imo-aspbzla843  chhs-24thizman2-fo-glyzdap           895  bhs-eta-ocho-zdab844  pippy-tetradi-no2-bsdap              896  2py-amn3-cpeo-betapy845  am2py-m24thiman2-nmo-bsdap           897  amim-tetradi-peo-asppha846  bzl-m24thizman2-oem-glyzdap          898  imhs-mepipen2-no2-zdab847  hythpym-dimen-meo-csdap              899  thpym-24thizman2-eoco-betadcph848  dmbim-eta-pyo-thizzdap               900  thpym-pazin-mes-betapy849  pyraz-pnymea-imo-psdap               901  tolhs-amo2-eoco-aspbzla850  2py-tetradi-4pho-bphabs              902  2py-mepipe-no2-zdab851  impy-props-meo-psdap                 903  thpym-trias-men-zdapee852  edothpym-thizn-cpeo-dfzdap           904  bhs-edian2-eoco-betapy853  dhim-eta-emo-dfzdap                  905  bhs-eta-no2-bnsdap854  bim-pnymea-5amo-zdab                 906  impy-amo2-hso-asppha855  piraz-dimephmep-chexo-betainyl       907  imhs-edian2-oeto-aspibua856  bhs-m24oxman2-imo-aspbzla            908  chmhs-24thizman2-5amo-dfzdap857  bzl-m24oxman2-meo-zdap               909  2py-eta-5pho-psdab858  imhs-am3-oem-nbeta34dimeoph          910  bhs-mepipen2-eoco-bhsdap859  me2py-eta-emo-aspbzla                911  bimhs-pnymea-meo-bnsdap860  cl3pyme-eta-napo-zdap                912  bhs-pyma2-napo-aspibua861  mam2py-thizn-imo-betadcph            913  pippy-mepazin-5amo-zlys862  npip-25oxman2-napo-betapy            914  2py-m25thiz-imo-bphabs863  thpym-mepipe-no1-betapy              915  piraz-24thiz-fo-dfzdap864  amim-pazin-napo-bphabs               916  edothpym-edia2-sem-nbetameph865  hythpym-eta-mes-glupha               917  impy-diphmem-meo-betapy866  bim-mepipe-no2-bhsdap                918  tolhs-amo2-no2-zdabs867  thpym-pazin-meo-zdab                 919  me-thizn-fo-asppha868  me-diphmep-no2-zdap                  920  dpam-25thizman2-chexo-csdap869  2py-thizo-men-zdab                   921  bhs-edian2-5pho-psdap870  z-25thiman2-napo-betadcph            922  phpip-m25oxman2-no1-osdap871  bzl-pazin-eoco-glyzdap               923  pippy-diphmem-5amo-psdap872  pippy-diphmep-oem-mezphe             924  hythpym-dimephmem-5amo-asppha873  imhs-25oxman2-fo-aval                925  chmhs-edian2-pro-betainyl874  ibhs-m24thizman2-baeo-betaet         926  bhs-pymea-no2-zdab875  bz-mepipen2-no2-csdap                927  im-amn2-no2-betainyl876  imhs-diphmep-pyo-bsdap               928  edothpym-am2-sem-nbetabnaphth877  am2py-thizn-meo-asppha               929  mam2py-pymea-men-zdab930  dmthpym-mepipe-no2-bphabs           982   thpym-edian2-eoco-betapy931  phhs-pipa-imo-betadcph              983   prhs-tetradi-ocho-bhsdap932  me2py-edian2-5amo-ibsdap            984   hythpym-pyma2-5amo-bhsdab933  thpym-dimen-fo-psdap                985   2py-eta-oem-zdap934  mam2py-pymea-oem-dfzdap             986   bim-24thiz-men-psdab935  amim-tridi-fo-bnsdap                987   amim-mea2s-hso-psdab936  ibhs-trias-no1-zlys                 988   piraz-edia2-oem-npsdap937  2py-pyma2-napo-thizzdap             989   dpam-dimephmep-imo-mezphe938  pyraz-am2-oem-nzdap                 990   pippy-ams2-meo-bnsdap939  me2py-dimen-peo-bhsdap              991   amim-dis-napo-asppha940  bhs-am2-oem-nbetabnaphth            992   amim-mepipe-imo-bphabs941  imhs-24thiz-no1-bnsdap              993   bhs-edian2-eoco-zdab942  2py-pazin-meo-psdab                 994   me2py-edian2-oem-aspbzla943  nmor-tetradi-meo-zdap               995   4pmhs-dimephmep-napo-zdap944  thpym-edian2-chexo-betapy           996   bzl-dimen-no1-betadcph945  am2py-24thizman2-imo-bphabs         997   2py-amn3-chexo-csdap946  4pmhs-m24thizman2-emo-aspbzla       998   gua-pymea-meteto-bhsdap947  imhs-pazin-eoco-betapy              999   chmhs-tridi-meo-zdab948  bimhs-25oxman2-imo-zdapee           1000  bimhs-amn2-no1-zlys949  me2py-thizo-meo-csdap               1001  me2py-am3-sem-nbetapy950  bimhs-amn2-fo-psdap                 1002  pippy-amo2-men-bhsdap951  piraz-pentas-4amo-aspibua           1003  pippy-trias-meo-mezphe952  piraz-eta-no1-psdap                 1004  mam2py-pyma2-imo-aspbzla953  imhs-mepipe-oem-psdap               1005  bz-eta2s-5amo-betapy954  bimhs-edian2-eoco-tsdap             1006  amim-pymea-men-zdab955  im-thizs-men-zdab                   1007  cl3pyme-amn2-mecpo-bhsdap956  mam2py-pazin-oem-ibsdap             1008  imhs-ams2-ocho-bhsdab957  tolhs-diphmep-5amo-psdap            1009  hythpym-m24thizman2-emo-958  thpym-pazin-ocho-bhsdap                   betadcph959  2py-pnymea-emo-bhsdap               1010  imhs-mepipe-meo-zdab960  2py-dimephmep-meo-glyzdap           1011  4pmhs-25oxman2-mes-dfzdap961  2py-butn-ocho-zdabs                 1012  bhs-mepipen2-pheo-bphabs962  imhs-amn3-no1-aspbzla               1013  tolhs-edian2-5amo-aspibua963  bim-eta-meo-betapy                  1014  npip-thizn-eoco-psdab964  2py-mepipen2-fo-mezphe              1015  bhs-dimephmep-chexo-bphabs965  bzl-ams2-5pho-dfzdap                1016  bhs-pazin-ocho-zdap966  4pmhs-pipmea-fo-betapy              1017  bim-mepipe-oem-bhsdap967  me2py-pentadi-mes-bhsdab            1018  bhs-m25thiz-aco-zdap968  pyrhs-tridi-meo-zdabs               1019  amim-mepipen2-ocho-bphabs969  amim-3diaz-mes-psdab                1020  dhim-din-nmo-zdabs970  pippy-tridi-5pho-bsdap              1021  bim-dimephmep-chexo-betainyl971  amim-pentas-mes-dfzdap              1022  2py-eta-meo-zdab972  am2py-mea-pheo-aval                 1023  pyrhs-edia2-sem-nbetabnaphth973  im-dis-imo-dfzdap                   1024  2py-pipmea-5amo-bphabs974  mepip-thizn-no2-dfzdap              1025  me2py-25oxman2-no1-betainyl975  deam-3pazin-oem-psdapee             1026  bim-m25thiz-oem-csdap976  bim-thizs-cnmo-bnsdap               1027  deam-am2-sem-nbetapy977  am2py-dimephmem-fo-bnsdap           1028  impy-dio-cno-betapy978  bhs-pyma2-men-zdabs                 1029  pippy-am3-oem-nzdap979  bhs-dimen-meo-glyzdap               1030  bimhs-dis-5amo-thizzdap980  am2py-eta-5pho-asppha               1031  am-propa2s-5pho-glyzdap981  am2py-diphmem-emo-asppha            1032  imhs-edian2-ocho-bsdap1033  phpip-tetradi-fo-asppha             1084  impy-edia2-oem-npsdap1034  npip-amo2-napo-betainyl             1085  me2py-dimen-cpeo-betapy1035  pippy-thizn-no1-psdap               1086  pyrhs-mepazin-men-bsdap1036  bimhs-din-aco-bsdap                 1087  me2py-dipch-ocho-csdap1037  npip-dipch-cnmo-aspibua             1088  pippy-mepipe-pheo-mezphe1038  am2py-3diaz-meo-psdapee             1089  bim-tetradi-men-betapy1039  ec-dipch-pyo-asppha                 1090  dhim-m24thiz-5pho-zdab1040  n2py-m25oxman2-4amo-glupha          1091  bim-am3diaz-no2-zdabs1041  nmor-amn2-5amo-mezphe               1092  impy-propa2s-men-bnsdap1042  hythpym-ams2-ocho-bphabs            1093  imhs-amn2-eoco-bsdap1043  emnim-eta-ocho-psdap                1094  bim-mepazin-ocho-bsdap1044  bzl-mepazin-pyo-bhsdab              1095  piraz-amo2-meo-aspibua1045  bhs-tridi-oeto-zdab                 1096  bhs-pazin-meo-zdab1046  emnim-tetradi-eoco-bsdap            1097  amim-pnymea-men-psdab1047  thpym-amn2-eoco-betapy              1098  pippy-3diaz-fo-psdab1048  amthiaz-pipa-men-oxal               1099  phpip-mea-emo-asppha1049  amim-pipmea-5amo-oxal               1100  4pmhs-25oxman2-5amo-glubzla1050  hythpym-24thiman2-pro-bsdap         1101  bim-pnymea-fo-csdap1051  imhs-mepipe-5amo-bnsdap             1102  bim-edian2-ocho-psdap1052  bhs-amn2-meo-psdab                  1103  2py-edian2-mes-bsdap1053  dhim-m24thizman2-no1-dfzdap         1104  bim-dimen-ocho-zdapee1054  thpym-mepipe-no2-zdap               1105  am-m24thizman2-ocho-psdap1055  am-dimen-no1-psdap                  1106  dmbim-eta2s-fo-asppha1056  amthiaz-edian2-4pho-bphabs          1107  bim-pazin-no2-zdap1057  4pmhs-24thizman2-ocho-aspibua       1108  morhs-m25thiz-emo-bnsdap1058  phpip-tetradi-emo-aspbzla           1109  n2py-amn3-eoco-zdap1059  mam2py-propn-fo-mezphe              1110  2pmhs-pipmea-napo-bhsdab1060  dhim-m25thiz-5amo-psdapee           1111  mam2py-25oxman2-napo-aspibua1061  mam2py-din-5amo-psdap               1112  nmhs-dimephmem-oem-bhsdap1062  n2py-pipmea-5pho-aspbzla            1113  ppy-mepipe2-oem-npsdap1063  gua-tridi-napo-ibsdap               1114  me2py-mepipe2-oem-nzdap1064  amim-mepipe2-oem-nbeta34-           1115  impy-25thiman2-men-csdap
  dimeoph                             1116  impy-24thizman2-5amo-bphabs1065  2py-mepipe-eoco-bsdap               1117  chmhs-amn2-eoco-psdab1066  mam2py-eta-meteto-csdap             1118  emnim-m25thiz-5pho-betapy1067  hythpym-mea-paco-bphabs             1119  amim-mepazin-pro-zlys1068  mam2py-dipch-oem-zdap               1120  mam2py-pazin-meto-bhsdap1069  thpym-pazin-mes-psdap               1121  bhs-edian2-ocho-bnsdap1070  dpam-pipa-men-aspbzla               1122  bhs-pazin-meo-bnsdap1071  piraz-amn3-cpeo-mezphe              1123  imhs-pyma2-ocho-zlys1072  2py-pymea-cno-bhsdap                1124  imhs-diphmem-mes-psdap1073  2py-24thiman-oem-bhsdab             1125  thpym-thizn-fo-asppha1074  thpym-trias-oem-mezphe              1126  npip-24thizman2-mes-psdab1075  nmor-eta-ocho-glyzdap               1127  bimhs-m24thiman2-4amo-aspibua1076  thpym-pazin-meo-betapy              1128  bimhs-mepazin-mmen-glyzdap1077  pyr-edia2-oem-nzdap                 1129  dmthpym-pnymea-peo-betapy1078  mam2py-tetradi-ocho-aspibua         1130  dhim-mepipe-men-dfzdap1079  2py-m25thiman2-napo-mezphe          1131  dhim-25oxman2-nmo-bnsdap1080  imhs-diphmem-mes-asppha             1132  mam2py-amo2-mes-psdap1081  thpym-eta-ocho-betapy               1133  piraz-pnymea-napo-zdab1082  bimhs-edian2-men-bphabs             1134  pyrhs-pyma2-oem-oxal1083  imhs-pazin-oem-bhsdap               1135  npip-pnymea-meo-psdap1136  pyr-m24thizman2-ocho-betapy          1187  me2py-diphmem-mes-csdap1137  am2py-dimephmep-no2-tsdap            1188  me-pymea-men-zdap1138  me2py-pentadi-no1-csdap              1189  nim-24thiz-5pho-glyzdap1139  bimhs-am2-sem-nzdab                  1190  hythpym-m24thiz-daco-ppsdap1140  bim-pipmea-5pho-psdap                1191  2py-mepipe-oem-zdap1141  mam2py-dich-eoco-zdap                1192  2py-tridi-mes-zdabs1142  cl3pyme-propa2s-fo-osdap             1193  thpym-pazin-eoco-betapy1143  imhs-mepipe-ocho-psdap               1194  am-tetras-men-aspibua1144  dhim-am3-oem-nzdab                   1195  piraz-din-mes-mezphe1145  emnim-edia2-oem-nbetapy              1196  hythpym-diphmem-5pho-psdapee1146  pyr-am2-oem-nbetameph                1197  bim-24oxman2-baeo-aspbzla1147  dhim-amo2-napo-psdap                 1198  moegua-dich-no1-betainyl1148  bim-edian2-meo-psdab                 1199  bhs-pipa-chexo-betainyl1149  bim-edian2-mes-psdab                 1200  thpym-pazi2n-chexo-betapy1150  bhs-amn2-oem-zdab                    1201  bhs-eta-eoco-psdab1151  imhs-propn-mes-bsdap                 1202  hythpym-dis-meo-aspaba1152  z-dimephmem-mes-asppha               1203  am2py-pentas-mes-mezphe1153  dmthpym-thizn-men-aspibua            1204  hythpym-tridi-mes-bphabs1154  amim-thizo-men-psdap                 1205  amim-tetradi-cpro-zdab1155  dmthpym-amo3-baeo-csdap              1206  bhs-pazin-eoco-psdap1156  imhs-hexadi-nmo-zdabs                1207  pippy-amo2-fo-psdab1157  4pmhs-pipmea-imo-bphabs              1208  im-diphmep-mes-zdap1158  bim-pazin-no1-betapy                 1209  impy-pazin-peo-glupha1159  thpym-25thiz-imo-ppsdap              1210  hythpym-m24thizman2-5pho-1160  piraz-thizn-oem-bphabs                     betapy1161  impy-pymea-chexo-mezphe              1211  am2py-25oxman2-5amo-zdab1162  me2py-diphmem-chexo-dfzdap           1212  mam2py-pyma2-paco-bnsdap1163  pippy-24thizman2-peo-bnsdap          1213  fthpym-am3diaz-5amo-bnsdap1164  2py-pipmeo-emo-dfzdap                1214  emnim-tridi-peo-betainyl1165  phpip-25oxman2-men-betainyl          1215  am4py-eta-cpro-betadcph1166  bim-amn2-oem-zdap                    1216  me2py-eta-chexo-ibsdap1167  mepip-pnymea-oem-betadcph            1217  bhs-thizo-ocho-glyzdap1168  thpym-pazin-ocho-bnsdap              1218  me2py-25oxman2-meo-zdabs1169  n2py-edian2-daco-bhsdap              1219  chmhs-amo2-no2-glyzdap1170  hythpym-trias-meteto-betadcph        1220  bhs-thizn-eoco-betapy1171  amim-pnymea-oem-glyzdap              1221  chhs-mea2s-chexo-zdap1172  prhs-am3-sem-nzdap                   1222  hythpym-n2nme2n-oem-zdab1173  amim-24thiman-5amo-psdap             1223  am2py-tetradi-no2-psdap1174  bim-eta-5pho-psdap                   1224  mepip-ms-daco-betapy1175  hythpym-amn3-paco-bhsdap             1225  piraz-dimen-emo-aspbzla1176  bimhs-m25thiman2-meo-betapy          1226  am2py-hexas-oem-dfzdap1177  pyraz-trias-emo-bhsdap               1227  bhs-edian2-oem-bhsdap1178  imhs-mepipe-no2-zdap                 1228  4pmhs-dis-oem-zdabs1179  dhim-mepipen2-5amo-aspibua           1229  dmthpym-am3diaz-5amo-aspibua1180  imhs-am3diaz-emo-aspibua             1230  thpym-tetradi-eoco-aspibua1181  am2py-m25thiz-paco-zorn              1231  impy-am2-oem-nbetabnaphth1182  hythpym-din-ocho-psdap               1232  impy-hexas-imo-psdab1183  edothpym-dimephmem-                  1233  2py-dimephmem-cpro-betapy
  mommo-bphabs                         1234  2py-24thiz-mes-aspbzla1184  me-mepipen2-no2-bphabs               1235  bimhs-dimephmem-no1-betapy1185  n2py-thizn-5amo-oxal                 1236  phhs-tetradi-meteto-asppha1186  bim-pazin-ocho-psdap                 1237  piraz-pyma2-fo-betapy1238  am2py-dimephmem-5pho-csdap         1290  phhs-25thizman2-men-aspibua1239  phhs-hexadi-meo-bphabs             1291  thpym-ams2-no1-zdap1240  moegua-am2-sem-npsdap              1292  pippy-pipa-eoco-bhsdab1241  amthiaz-m24thiman2-chexo-zorn      1293  edothpym-mepazin-pheo-zdab1242  piraz-eta-cno-bhsdap               1294  me2py-tetradi-oem-zdap1243  2py-amo2-meo-betapy                1295  am-ams2-fo-aval1244  mam2py-m25thiz-chexo-zdap          1296  bim-eta-5pho-betapy1245  2py-hexas-peo-aspibua              1297  impy-pyma2-men-bnsdap1246  2py-pazin-mes-zdap                 1298  edothpym-pazin-emo-aspibua1247  menim-25thiz-pheo-psdap            1299  impy-24thiz-cnmo-bnsdap1248  chmhs-diphmem-oem-bnsdap           1300  nim-pazin-emo-bhsdap1249  ec-24thiz-mes-bsdap                1301  me2py-diphmep-5pho-dfzdap1250  2py-eta-mmen-zlys                  1302  thpym-eta-ocho-psdab1251  dmam-trias-chexo-bhsdab            1303  gua-am2-sem-npsdap1252  impy-din-meo-aspibua               1304  me2py-25oxman2-emo-bphabs1253  me2py-propa2s-5pho-aspibua         1305  imhs-thizo-meto-asppha1254  bhs-pyma2-chexo-bhsdap             1306  thpym-eta-emo-glyzdap1255  ibhs-amn2-emo-bnsdap               1307  pippy-diphmem-peo-betainyl1256  imhs-diphmem-napo-bphabs           1308  2py-edian2-meo-zdap1257  thpym-pipmea-peo-glyzdap           1309  bim-amn2-eoco-psdap1258  mam2py-din-emo-zdab                1310  mam2py-24thizman2-pheo-1259  mepip-pentadi-napo-betapy                glyzdap1260  bimhs-tridi-meto-dfzdap            1311  pippy-trias-4pho-aspbzla1261  bhs-mepipe-no1-bnsdap              1312  imhs-dimen-no1-aspbzla1262  imhs-eta-meo-zdab                  1313  phpip-tetradi-eoco-bhsdap1263  mam2py-n2o2n-chexo-aspibua         1314  2py-tetradi-fo-zdap1264  nmhs-pnymea-eoco-zdapee            1315  nmor-amn2-5amo-bsdap1265  dpam-pipmea-5amo-bhsdap            1316  pyr-diphmep-aco-psdab1266  4pmhs-pazin-mommo-glyzdap          1317  me2py-25thiz-cpro-oxal1267  imhs-tetradi-4pho-ibsdap           1318  imhs-mepipe-meo-psdap1268  bhs-25thiman2-fo-glyzdap           1319  ec-thizn-imo-zdab1269  imhs-dimephmem-oem-bhsdab          1320  bzl-pipa-imo-bhsdab1270  impy-24thiman2-eoco-bhsdab         1321  menim-amo3-mes-zdabs1271  am2py-pyma2-pyo-ppsdap             1322  thpym-24thizman2-men-zdapee1272  bimhs-tridi-aco-tsdap              1323  dmam-ams2-men-bnsdap1273  nmhs-eta-no2-aspibua               1324  2py-amn2-ocho-betapy1274  bim-pazin-no2-bsdap                1325  bhs-diaz-meo-ibsdap1275  mam2py-trias-imo-bnsdap            1326  impy-n2o2n-napo-glyzdap1276  me2py-m25thiz-4pho-zdabs           1327  amim-pipa-napo-bnsdap1277  imhs-pnymea-mes-aspibua            1328  2py-edian2-mes-bhsdap1278  thpym-amn2-5pho-psdap              1329  bim-amn2-mes-betapy1279  morhs-diphmep-5amo-osdap           1330  piraz-diphmem-fo-glyzdap1280  thpym-edian2-no1-bhsdap            1331  gua-tetradi-no1-aspibua1281  tolhs-pnymea-5amo-zdab             1332  bhs-ams2-aco-zdab1282  cl3pyme-25oxman2-5pho-bhsdap       1333  deam-amo2-emo-psdab1283  me2py-24thiman2-meo-mezphe         1334  pyrhs-m25oxman2-no2-zdabs1284  pyrhs-25oxman2-ocho-zdab           1335  4pmhs-tridi-mes-zdap1285  2py-dimen-mmen-csdap               1336  hythpym-eta-mes-csdap1286  pyraz-24thiman2-peo-bphabs         1337  bhs-pazin-ocho-bhsdap1287  npip-dio-fo-csdap                  1338  thpym-eta-oem-zdab1288  impy-pnymea-men-betapy             1339  pyrhs-amo2-daco-dfzdap1289  piraz-24thiz-no2-bphabs            1340  menim-propa2s-chexo-zdab1341  im-din-mes-betainyl                1393  dmthpym-dimen-5pho-bhsdab1342  2py-eta-ocho-psdab                 1394  bim-pazin-hso-mezphe1343  bhs-tetradi-fo-aspbzla             1395  2py-pipa-nmo-zdab1344  pippy-ams2-napo-betadcph           1396  pippy-pipmea-5pho-bhsdap1345  me2py-25thiz-fo-bphabs             1397  chmhs-tetras-no1-mezphe1346  me2py-25oxman2-meo-psdapee         1398  fthpym-m25thiman2-eoco-bphabs1347  imhs-pazin-mes-zdap                1399  amim-m25thiz-napo-csdap1348  me2py-pipmea-5pho-zdapee           1400  piraz-din-eoco-mezphe1349  nmor-m25oxman2-no2-mezphe          1401  2py-pipmea-mes-aspaba1350  cl3pyme-dimephmem-mes-bhsdab       1402  2py-amn3-napo-zdab1351  imhs-pipmea-emo-csdap              1403  mam2py-24thizman2-meo-dfzdap1352  bzl-tridi-5amo-glubzla             1404  piraz-amo2-eoco-dfzdap1353  pyrhs-dis-mes-zdab                 1405  moegua-mea2s-no2-psdap1354  emnim-amn2-chexo-bphabs            1406  thpym-pazin-5pho-bsdap1355  chhs-mepipe2-oem-npsdap            1407  bhs-amn2-eoco-bhsdap1356  imhs-dis-no2-betainyl              1408  am2py-pyma2-napo-zdabs1357  dmthpym-pymea-peo-bsdap            1409  amim-dich-eoco-tsdap1358  bhs-diphmem-emo-bhsdap             1410  bhs-edian2-ocho-bsdap1359  imhs-hexadi-5pho-zdab              1411  2py-m25thiz-imo-aspbzla1360  impy-m24oxman2-fo-betainyl         1412  am2py-pazin-5pho-csdap1361  bimhs-dimen-fo-betainyl            1413  pippy-am2-sem-nbetameph1362  thpym-pazin-ocho-zdap              1414  thpym-diphmep-no1-aspibua1363  bim-pazin-eoco-psdap               1415  nmhs-dich-eoco-zdab1364  am2py-dis-meo-csdap                1416  bim-pipmea-men-bhsdap1365  imhs-amn2-eoco-bhsdap              1417  thpym-mepipen2-mes-betaet1366  deam-pyma2-eoco-tsdap              1418  edothpym-indan2-eoco-zdabs1367  me2py-tetradi-no1-aval             1419  hythpym-m24thiz-cnmo-csdap1368  n2py-pymea-meo-psdab               1420  me2py-25oxman2-emo-glupha1369  bim-amn2-mes-zdab                  1421  edothpym-dimephmep-4amo-csdap1370  dhim-amn3-napo-aspbzla             1422  ec-am3-oem-nbeta34dimeoph1371  ec-m24thizman2-emo-ppsdap          1423  thpym-eta-eoco-bhsdap1372  imhs-m25thiz-oem-ppsdap            1424  dmam-tetradi-no2-psdap1373  impy-dis-meo-zlys                  1425  mam2py-pymea-no1-mezphe1374  dhim-dimephmem-pyo-bsdap           1426  dhim-m25thiz-5pho-osdap1375  nim-amo2-mes-bhsdap                1427  amim-thizn-chexo-bnsdap1376  tolhs-m24thiman2-ocho-zdab         1428  am2py-amn3-no1-psdap1377  impy-25oxman2-pyo-zdabs            1429  bhs-m24thizman2-men-betadcph1378  bim-edian2-ocho-zdab               1430  phpip-dimephmem-chexo-zdabs1379  cl3pyme-dimen-men-psdab            1431  chmhs-m24thiman2-oem-bphabs1380  imhs-diphmep-oem-betapy            1432  bim-dimephmem-men-zdap1381  imhs-tetradi-5amo-bsdap            1433  am2py-pentas-meo-bnsdap1382  morhs-pipmea-pyo-betainyl          1434  morhs-pipmea-5pho-aspibua1383  4pmhs-n24thiman-napo-aspibua       1435  mam2py-mepazin-pheo-mezphe1384  hythpym-pipa-mmen-aspbzla          1436  mam2py-am3-sem-nzdab1385  bimhs-amn3-eoco-mezphe             1437  impy-pipa-men-zdab1386  am4py-amn2-ocho-zdabs              1438  amim-24oxman2-emo-betadcph1387  bhs-pazin-no1-bsdap                1439  imhs-props-imo-bsdap1388  bzl-mepipen2-peo-dfzdap            1440  imhs-mepipe-5pho-psdap1389  2pmhs-dis-imo-zdabs                1441  me2py-pazin-napo-bsdap1390  fthpym-25oxman2-chexo-mezphe       1442  mam2py-mepipen2-pyo-zdap1391  mepip-m25thiman2-mommo-bhsdap      1443  2py-eta-mes-bnsdap1392  bimhs-edian2-oem-aspbzla           1444  amim-tetradi-meto-betapy1445  am-pymea-5pho-betadcph                1497  pippy-m24oxman2-mes-bhsdab1446  amim-pipa-eoco-aspibua                1498  thpym-mepipe-ocho-bsdap1447  am2py-mepipe2-oem-nbetapy             1499  impy-amn3-5pho-bhsdab1448  pippy-am3-sem-nzdap                   1500  bim-propn-nmo-bhsdab1449  mam2py-dimephmem-fo-betainyl          1501  bhs-mepipe-napo-ibsdap1450  2py-dimephmem-oem-zdab                1502  thpym-mepipe2-oem-nzdap1451  me2py-tetradi-pyo-psdapee             1503  2py-3pazin-4amo-psdab1452  bhs-mepazin-mes-bnsdap                1504  imhs-pipa-meo-betapy1453  imhs-ms-fo-csdap                      1505  chhs-pipa-no2-zdap1454  imhs-pazi2n-chexo-tsdap               1506  hythpym-thizn-meo-psdab1455  pippy-diphmep-emo-bnsdap              1507  me-pnymea-emo-bnsdap1456  bhs-pnymea-oem-bhsdab                 1508  menim-dimephmem-meto-zdabs1457  deam-m25thiz-chexo-asppha             1509  bimhs-mepipen2-cpeo-zorn1458  hythpym-3pazin-imo-zdab               1510  bhs-pazin-pyo-asppha1459  thpym-diphmem-napo-csdap              1511  chhs-pazin-oem-betapy1460  pippy-diphmem-chexo-zdab              1512  bim-pazin-ocho-bhsdap1461  ppy-thizn-ocho-glyzdap                1513  imhs-m24thizman2-cnmo-asppha1462  dhim-pipa-oem-psdap                   1514  2py-edian2-oem-psdab1463  imhs-ams2-no1-zdab                    1515  imhs-tetradi-mmen-zdabs1464  bim-mepipe-no2-psdap                  1516  2py-edian2-no2-psdap1465  chmhs-dis-imo-aspbzla                 1517  dmam-dimephmem-men-bhsdap1466  bim-mea2s-meo-oxal                    1518  am2py-24thiz-mes-bphabs1467  bz-25thizman2-mmen-asppha             1519  imhs-amn2-no2-bhsdap1468  dhim-mepipe-5amo-bphabs               1520  pyr-dis-aco-bhsdap1469  bhs-pazin-ocho-psdab                  1521  chmhs-pymea-daco-aspibua1470  amim-dimephmep-5amo-bhsdap            1522  impy-ams2-men-aspbzla1471  tolhs-diphmem-no1-zlys                1523  morhs-pyma2-no2-zdabs1472  imhs-pipmeo-fo-aspbzla                1524  im-24thiz-fo-zdabs1473  phhs-dimephmem-baeo-dfzdap            1525  hythpym-tetradi-cpro-betadcph1474  hythpym-3diaz-paco-aval               1526  2py-eta-oem-betapy1475  2py-pentas-ocho-bhsdab                1527  piraz-thizn-baeo-bphabs1476  me-n24thiman-fo-dfzdap                1528  bim-amo3-oem-aval1477  pyr-25oxman2-5amo-bnsdap              1529  npip-mea2s-chexo-betapy1478  thpym-trias-5pho-ibsdap               1530  bim-diphmep-meo-bphabs1479  bim-amn3-no2-psdab                    1531  bz-mepipe2-oem-nzdap1480  dmthpym-dipch-imo-aspibua             1532  2py-pyma2-eoco-asppha1481  chhs-24thiz-fo-aspibua                1533  bim-dimephmep-emo-asppha1482  dhim-diphmem-no2-zdap                 1534  am2py-amn2-5pho-csdap1483  me2py-n24thiman-5amo-psdap            1535  mam2py-24thiman-napo-zdap1484  am-dimephmep-chexo-asppha             1536  pippy-diphmem-oem-betadcph1485  imhs-thizo-emo-glubzla                1537  impy-amo2-5pho-betadcph1486  prhs-tridi-napo-zdabs                 1538  bimhs-am2-sem-nbetapy1487  2py-edian2-5pho-psdap                 1539  imhs-2pazin-aco-mezphe1488  n2py-am3-oem-nzdab                    1540  dhim-amo2-ocho-aspbzla1489  cl3pyme-eta-no1-bphabs                1541  bim-m24thizman2-eoco-betapy1490  ibhs-pymea-oem-zdab                   1542  ec-eta-imo-psdab1491  thpym-amn2-mes-bhsdap                 1543  dmbim-am3-oem-nzdab1492  thpym-24thiz-no2-tsdap                1544  cl3pyme-amn2-mes-zdab1493  pyr-24thizman2-eoco-betainyl          1545  dpam-amn2-emo-dfzdap1494  bim-edian2-meo-betapy                 1546  bhs-edian2-napo-bhsdab1495  piraz-propn-chexo-aspbzla             1547  pyrhs-ms-oem-zdab1496  dmthpym-am3-sem-nzdap                 1548  im-mepazin-baeo-ppsdap1549  pippy-ams2-emo-psdap               1601  pyr-dimephmep-no1-bsdap1550  imhs-pazin-mes-bsdap               1602  amim-butn-4amo-glyzdap1551  hythpym-m25thiz-emo-bsdap          1603  bim-dimen-emo-glubzla1552  phpip-pipa-eoco-csdap              1604  impy-propa2s-ocho-dfzdap1553  mam2py-pazi2n-no1-asppha           1605  dhim-amn3-men-bphabs1554  bimhs-dich-meo-zdab                1606  mam2py-dis-emo-glyzdap1555  z-tridi-eoco-betapy                1607  impy-dimephmem-ocho-zdabs1556  z-am3-oem-nzdab                    1608  am2py-m24thizman2-emo-bhsdap1557  2py-pnymea-oem-zdab                1609  bhs-pyma2-no2-bnsdap1558  thpym-eta-mes-psdab                1610  me2py-diphmep-ocho-mezphe1559  hythpym-mepipe-oem-betainyl        1611  bimhs-propa2s-mecpo-bhsdap1560  am2py-propn-mes-bsdap              1612  hythpym-mepipe2-sem-nbeta-1561  am2py-ams2-paco-bhsdab                   34dimeoph1562  imhs-amn2-meo-bsdap                1613  bimhs-pentadi-napo-aspibua1563  bhs-edia2-sem-nbetapy              1614  thpym-mepipe-eoco-psdap1564  moegua-dis-meo-csdap               1615  gua-tetras-emo-bphabs1565  pyr-tetradi-mommo-dfzdap           1616  thpym-am2-oem-nbetapy1566  2py-pnymea-no1-glyzdap             1617  emnim-mepipen2-eoco-zdabs1567  n2py-edian2-men-bphabs             1618  pippy-m25thiman2-eoco-bphabs1568  me2py-pentadi-meo-zdap             1619  tolhs-dich-imo-oxal1569  cl3pyme-pipmea-no2-dfzdap          1620  dmbim-edian2-men-bhsdap1570  2py-dis-meo-bhsdab                 1621  bimhs-dimephmem-no1-zdab1571  me2py-m24thizman2-oeto-psdab       1622  bhs-hexadi-fo-glyzdap1572  bim-diphmem-chexo-asppha           1623  hythpym-pymea-napo-bsdap1573  pippy-pymea-5pho-glyzdap           1624  pippy-mepipe2-oem-nbetapy1574  pippy-trias-no2-betainyl           1625  npip-edia2-oem-nbetabnaphth1575  edothpym-eta-napo-aspbzla          1626  bimhs-edian2-cpeo-bhsdap1576  dmbim-pipmeo-emo-zdab              1627  dmbim-tetradi-men-bhsdab1577  bim-pazin-ocho-bsdap               1628  pippy-24thiman2-eoco-bhsdap1578  2py-n2nme2n-napo-aspibua           1629  bzl-m25oxman2-cnmo-dfzdap1579  impy-mepazin-napo-bhsdab           1630  pippy-pipmes-cnmo-psdap1580  thpym-diaz-meo-bnsdap              1631  im-n2nme2n-no2-bsdap1581  bim-edia2-oem-npsdap               1632  bim-thizn-no1-bsdap1582  dhim-dimephmem-hso-asppha          1633  thpym-2pazin-meo-mezphe1583  npip-mepazin-pro-bphabs            1634  tolhs-pipa-eoco-bnsdap1584  thpym-eta-eoco-aspbzla             1635  impy-dich-ocho-betaet1585  imhs-24thizman2-mommo-aval         1636  imhs-emn2-meo-betapy1586  am2py-edian2-aco-psdab             1637  ibhs-mepipe-5pho-betadcph1587  bimhs-amn3-mecpo-glyzdap           1638  me-eta2s-no1-aspbzla1588  mam2py-dimephmem-cpro-bphabs       1639  2py-mepipe-meo-zdab1589  bim-diphmep-ocho-psdap             1640  am2py-amo2-fo-psdapee1590  ppy-diphmem-eoco-bnsdap            1641  ibhs-edian2-eoco-csdap1591  2py-mepipen2-daco-bphabs           1642  me-amo2-eoco-zdap1592  dmam-amo3-cnmo-bhsdab              1643  bhs-mepipe-ocho-zdap1593  imhs-eta-cnmo-betainyl             1644  bim-tetras-meteto-tsdap1594  pyraz-hexadi-eoco-bnsdap           1645  nmhs-dimephmep-napo-psdap1595  pippy-24thiz-oeto-glyzdap          1646  amim-mepipen2-meo-psdab1596  2pmhs-mepipe-fo-psdab              1647  bim-amn2-oem-betapy1597  nim-pipmea-mes-betapy              1648  mepip-dis-napo-zdabs1598  phhs-n2nme2n-ocho-zdap             1649  bim-mepazin-meo-aspibua1599  dmthpym-edian2-mes-bphabs          1650  npip-pymea-men-bphabs1600  pippy-3diaz-emo-betadcph           1651  mam2py-tridi-ocho-betainyl1652  ec-m25thizman2-meto-glyzdap         1702  bim-diphmep-mecpo-bhsdab1653  am2py-pazin-fo-zlys                 1703  amim-tetradi-fo-zorn1654  hythpym-24thiz-no2-asppha           1704  thpym-tetradi-eoco-bhsdap1655  imhs-eta-eoco-bsdap                 1705  morhs-diphmem-imo-zdab1656  dhim-mea2s-men-tsdap                1706  ppy-m25thiman2-pyo-betadcph1657  am2py-tetradi-5amo-psdap            1707  imhs-pazin-fo-csdap1658  bhs-amn3-napo-glyzdap               1708  morhs-pipmea-5amo-asppha1659  thpym-din-fo-bhsdap                 1709  am2py-diphmep-cno-zdabs1660  am2py-mepipe2-oem-nbetameph         1710  thpym-m25thiz-4pho-ppsdap1661  hythpym-24thiman2-napo-             1711  imhs-amn2-no2-zdab
  aspbzla                             1712  bhs-amn2-ocho-bhsdap1662  me2py-m25thiz-eoco-bphabs           1713  bimhs-propa2s-peo-mezphe1663  dpam-m25thiz-oeto-zdap              1714  thpym-pipmea-5pho-aspibua1664  edothpym-pentas-fo-aspbzla          1715  dhim-25thizman2-no1-zdab1665  tolhs-tetradi-no1-bhsdab            1716  amthiaz-24oxman2-imo-bhsdab1666  mam2py-am3diaz-men-bhsdab           1717  2py-pymea-aco-psdab1667  bimhs-pyma2-chexo-zorn              1718  imhs-mepipe-no2-glyzdap1668  2py-ams2-ocho-csdap                 1719  4pmhs-n2nme2n-imo-glubzla1669  ppy-diphmem-5pho-glupha             1720  bimhs-dimephmem-napo-betadcph1670  2py-dimephmem-ocho-asppha           1721  z-edia2-oem-nbetapy1671  dhim-pipmes-chexo-asppha            1722  thpym-edian2-mes-bhsdap1672  thpym-pentadi-men-tsdap             1723  tolhs-dimephmem-ocho-betapy1673  mam2py-thizn-men-bhsdap             1724  pyrhs-trias-men-asppha1674  impy-eta2s-chexo-thizzdap           1725  mam2py-n2o2n-napo-glyzdap1675  impy-eta-emo-zdabs                  1726  thpym-thizo-meo-betainyl1676  bim-hexas-4amo-betaet               1727  chhs-ams2-mes-betainyl1677  pippy-m25thizman2-chexo-            1728  me2py-am3-sem-npsdap
  bphabs                              1729  2py-dio-imo-bphabs1678  nmhs-thizn-chexo-psdab              1730  mam2py-indan2-oem-betainyl1679  impy-3pazin-5pho-psdap              1731  dhim-dimen-emo-betadcph1680  2py-tridi-chexo-glubzla             1732  pippy-24thiman-men-zdap1681  2py-dis-cnmo-betapy                 1733  impy-dis-emo-aspibua1682  pippy-mepipen2-meo-psdap            1734  imhs-amn2-5pho-zdab1683  mam2py-dimen-emo-aspbzla            1735  impy-m25thiz-ocho-csdap1684  mam2py-dis-napo-zdap                1736  bz-pentadi-meo-bsdap1685  2py-pazin-ocho-psdab                1737  thpym-mepipe-no1-zdab1686  me2py-amo2-napo-asppha              1738  2py-eta-peo-aspibua1687  impy-m25thiz-emo-ppsdap             1739  mam2py-din-fo-tsdap1688  me2py-thizs-mmen-mezphe             1740  thpym-edian2-5pho-psdab1689  bim-eta-ocho-bsdap                  1741  thpym-tetradi-oem-ibsdap1690  moegua-mepipen2-oem-glyzdap         1742  amim-amn3-imo-bsdap1691  dmthpym-m25thiz-eoco-betadcph       1743  hythpym-eta-fo-aspibua1692  prhs-trias-meteto-zdabs             1744  ppy-24oxman2-imo-zdab1693  thpym-m24thizman2-fo-mezphe         1745  edothpym-dimephmem-5amo-osdap1694  impy-edian2-no2-psdap               1746  pyrhs-dimephmem-meo-betapy1695  phhs-eta-napo-dfzdap                1747  bhs-mepipe-ocho-bhsdap1696  impy-hexadi-oem-zlys                1748  2py-mepipe-no1-bsdap1697  pyraz-dich-5amo-psdap               1749  piraz-dimephmep-emo-aspibua1698  npip-pnymea-mes-zdap                1750  bhs-eta-meo-zdap1699  chmhs-2pazin-men-aspbzla            1751  piraz-dimephmep-emo-dfzdap1700  edothpym-dis-nmo-mezphe             1752  me2py-dimephmem-imo-bhsdap1701  dhim-diphmem-no1-ibsdap             1753  npip-amo2-no2-betapy1754  bhs-dimephmep-4pho-osdap            1805  dhim-3pazin-cnmo-bhsdap1755  2py-edian2-oem-zdap                 1806  z-pipmea-eoco-bphabs1756  dhim-pipmea-emo-zdab                1807  mam2py-am3diaz-5amo-bsdap1757  nim-24thiz-pro-aspibua              1808  imhs-24thiz-imo-asppha1758  dhim-edian2-daco-glyzdap            1809  morhs-m24thizman2-chexo-1759  4pmhs-trias-no1-betadcph                  bhsdab1760  edothpym-dis-no1-bphabs             1810  phpip-diphmep-oem-dfzdap1761  impy-m24thizman2-cpeo-bhsdab        1811  me2py-ams2-napo-mezphe1762  bim-eta-mes-zdab                    1812  phpip-24thiz-no1-psdap1763  nmor-eta2s-emo-psdap                1813  bhs-edian2-no2-bsdap1764  dhim-tridi-mes-zdap                 1814  dhim-edian2-cnmo-dfzdap1765  impy-mepipe2-oem-nbetameph          1815  bimhs-pipmea-meto-ibsdap1766  bim-m24thiman2-5amo-bsdap           1816  piraz-dimephmep-meo-glyzdap1767  impy-amn3-imo-bhsdap                1817  mepip-mepipen2-napo-psdab1768  amim-25thizman2-emo-aspibua         1818  imhs-edian2-oem-psdap1769  ibhs-n2nme2n-imo-aspbzla            1819  mam2py-dimephmem-pheo-mezphe1770  4pmhs-mepipe2-oem-nbetab            1820  thpym-mepipen2-cno-zdabs
  naphth                              1821  bim-mepipen2-no2-bnsdap1771  thpym-24thizman2-fo-zdabs           1822  hythpym-ams2-5pho-psdab1772  chmhs-dimephmem-napo-dfzdap         1823  hythpym-pyma2-daco-mezphe1773  me2py-pyma2-daco-ibsdap             1824  impy-dis-oeto-aspbzla1774  bim-mepazin-cnmo-zorn               1825  chmhs-tridi-imo-psdap1775  me2py-tetradi-ocho-zdapee           1826  imhs-m24thizman2-oem-bhsdap1776  amim-pyma2-no1-csdap                1827  npip-dimephmem-men-bphabs1777  am2py-mepazin-oem-bhsdap            1828  pippy-trias-imo-bhsdab1778  bhs-amn2-5pho-bhsdap                1829  tolhs-pymea-no1-dfzdap1779  edothpym-pazin-napo-csdap           1830  amim-m24thizman2-imo-thizzdap1780  thpym-amo3-no2-csdap                1831  me2py-eta-emo-psdab1781  am4py-dimephmem-mes-dfzdap          1832  bim-pazin-5pho-betapy1782  amim-edia2-sem-nbetabnaphth         1833  amim-thizn-fo-zdapee1783  2py-propn-chexo-betapy              1834  am2py-mepipe-pyo-bhsdap1784  bimhs-din-mecpo-psdap               1835  mam2py-thizn-5pho-dfzdap1785  bimhs-mepipe-imo-bhsdap             1836  dhim-24thizman2-napo-psdab1786  mepip-eta-nmo-asppha                1837  me2py-25oxman2-napo-dfzdap1787  tolhs-2pazin-napo-bhsdap            1838  amim-am2-oem-nbetapy1788  me2py-dipch-chexo-zdabs             1839  bim-24thiz-cno-glyzdap1789  2py-amn2-no2-zdap                   1840  piraz-2pazin-chexo-betaet1790  bim-mepazin-oem-betainyl            1841  cl3pyme-mepazin-chexo-glyzdap1791  thpym-eta-meo-betapy                1842  2py-ams2-eoco-betapy1792  impy-dimephmep-5amo-bnsdap          1843  mam2py-am2-oem-nzdap1793  piraz-2pazin-no2-aspibua            1844  imhs-pazin-5pho-betapy1794  imhs-pnymea-cnmo-zdap               1845  thpym-edian2-eoco-zdab1795  thpym-m25thiman2-fo-zdap            1846  impy-m24thizman2-ocho-betapy1796  amim-dimen-no2-aspibua              1847  cl3pyme-diphmem-5pho-bnsdap1797  thpym-amn2-eoco-psdab               1848  4pmhs-ams2-pheo-oxal1798  amim-tetradi-ocho-aspbzla           1849  2py-pymea-no1-betadcph1799  pippy-dis-fo-betadcph               1850  pippy-am3-oem-nbetapy1800  bhs-m24oxman2-meto-glubzla          1851  piraz-tridi-pro-betainyl1801  im-m24oxman2-eoco-psdap             1852  2py-eta-men-bnsdap1802  hythpym-amo2-emo-glubzla            1853  phpip-mepipe-eoco-betainyl1803  am2py-pipa-mommo-ibsdap             1854  edothpym-amn3-pyo-zdabs1804  bhs-amn2-ocho-bhsdap                1855  im-pentas-ocho-betadcph1856  cl3pyme-ams2-mes-betadcph             1906  imhs-am2-sem-nbetameph1857  bim-pyma2-ocho-betadcph               1907  dmthpym-pymea-imo-aspibua1858  bim-amn2-no1-bsdap                    1908  bhs-mea-imo-betapy1859  imhs-pazin-no1-bsdap                  1909  hythpym-mepipe2-sem-nzdap1860  dhim-dimephmep-oeto-betainyl          1910  menim-24thiman2-napo-bhsdab1861  bim-thizn-no2-zdab                    1911  amim-pazin-fo-zdap1862  prhs-pazin-5pho-csdap                 1912  amim-props-no1-zdab1863  chmhs-m24oxman2-mommo-bphabs          1913  bim-eta-5pho-psdab1864  2py-mepipen2-men-dfzdap               1914  am2py-thizs-eoco-zdap1865  npip-edia2-sem-nbetameph              1915  phpip-dimen-5pho-betainyl1866  bhs-tridi-ocho-bnsdap                 1916  bhs-edian2-eoco-bnsdap1867  bhs-pazin-no2-betadcph                1917  am2py-dimephmem-emo-bsdap1868  moegua-amo2-chexo-zdap                1918  bz-mepipe-meo-glubzla1869  mepip-amn3-emo-aspibua                1919  me2py-m25thiz-no2-aspbzla1870  dmthpym-am3-sem-nbeta34-              1920  ppy-pyma2-men-csdap
  dimeoph                               1921  me2py-ams2-mes-bphabs1871  emnim-diphmem-oeto-zlys               1922  bhs-dimen-emo-bphabs1872  ibhs-m25thiz-chexo-bphabs             1923  emnim-24oxman2-fo-betapy1873  thpym-pyma2-imo-glyzdap               1924  imhs-diphmem-emo-aspibua1874  gua-24thiz-oeto-psdap                 1925  hythpym-mepipe-cnmo-betadcph1875  am2py-thizn-mes-csdap                 1926  dhim-n24thiman-cno-csdap1876  amthiaz-24thizman2-pheo-csdap         1927  mam2py-pipmea-nmo-csdap1877  am4py-mepipe2-oem-nbetameph           1928  z-ms-meo-zdab1878  ec-m25thiman2-meo-aspibua             1929  am4py-pyma2-cno-psdap1879  dhim-amn3-cpro-bhsdab                 1930  am4py-mepazin-no2-betainyl1880  dmthpym-m24thizman2-5amo-             1931  thpym-eta-meo-psdab
  bhsdap                                1932  chhs-pymea-napo-bhsdap1881  imhs-mepipe-oem-zdap                  1933  pyraz-m24thizman2-meo-tsdap1882  bim-pazin-oem-betapy                  1934  pippy-24thizman2-4amo-mezphe1883  bhs-eta-oem-betapy                    1935  imhs-edian2-eoco-zdap1884  dhim-props-imo-zlys                   1936  amim-thizo-5amo-bnsdap1885  thpym-pipa-eoco-mezphe                1937  me2py-24thizman2-cnmo-zdabs1886  2py-ams2-5pho-zdabs                   1938  thpym-pazin-ocho-betapy1887  hythpym-amo2-eoco-mezphe              1939  impy-m24thizman2-5amo-aspbzla1888  bim-eta-meo-zdap                      1940  amim-tridi-5amo-asppha1889  dhim-pipmes-5pho-zdap                 1941  thpym-dimephmep-emo-glyzdap1890  hythpym-thizn-mes-zdabs               1942  thpym-am3diaz-napo-csdap1891  gua-pipa-fo-bphabs                    1943  prhs-pentas-eoco-bsdap1892  nmhs-pipmea-mes-zdabs                 1944  phhs-pipmea-5amo-dfzdap1893  dhim-trias-imo-zdab                   1945  prhs-dich-mes-zdapee1894  mam2py-pymea-eoco-csdap               1946  thpym-edian2-5pho-bnsdap1895  imhs-eta-eoco-betapy                  1947  piraz-m24thizman2-napo-bhsdap1896  dpam-mepazin-4amo-glyzdap             1948  dmam-amn3-cnmo-zdabs1897  bimhs-diphmep-no2-thizzdap            1949  phpip-pymea-cno-aspibua1898  am2py-m24thizman2-mes-psdap           1950  bhs-pipa-mes-ppsdap1899  nmhs-am2-oem-nbetapy                  1951  am4py-trias-mes-bphabs1900  bhs-mepipen2-napo-bhsdap              1952  am2py-dimephmem-chexo-psdab1901  dhim-diphmem-mes-zlys                 1953  dmthpym-dimephmem-mmen-1902  me2py-25thiz-eoco-zdabs                     betadcph1903  2py-dis-imo-psdap                     1954  pippy-mepipen2-emo-betadcph1904  bim-mepipe-5pho-bnsdap                1955  bim-mepipe-meo-betapy1905  edothpym-pazin-mes-betainyl           1956  moegua-mepipe-5amo-zdabs1957  dhim-mepipen2-emo-bphabs           2008  dmam-amo3-ocho-bhsdap1958  z-eta-no2-betadcph                 2009  impy-am3-sem-nzdab1959  dpam-pnymea-men-bhsdab             2010  dpam-2pazin-daco-asppha1960  bimhs-diphmem-chexo-bphabs         2011  bhs-m25thiz-chexo-psdap1961  2pmhs-thizn-mes-mezphe             2012  impy-diaz-peo-aspibua1962  piraz-25oxman2-5pho-zdap           2013  dhim-pymea-meo-aspibua1963  imhs-amn2-5pho-bsdap               2014  bhs-pipmea-no1-betainyl1964  phhs-24oxman2-eoco-zdapee          2015  bimhs-n24thiman-mes-betapy1965  2py-pazin-ocho-aspibua             2016  dhim-pipmes-fo-psdap1966  ibhs-dipch-emo-betapy              2017  phhs-dimen-ocho-zdab1967  bhs-amn2-eoco-psdap                2018  thpym-dipch-no2-bphabs1968  thpym-tridi-4amo-asppha            2019  bhs-mea-meteto-asppha1969  ec-ams2-meo-aspibua                2020  morhs-tetradi-4pho-psdab1970  2py-pazin-meo-psdap                2021  amthiaz-n2nme2n-baeo-bnsdap1971  2py-pazin-fo-csdap                 2022  pippy-mepipe-eoco-bhsdab1972  thpym-pazin-ocho-bsdap             2023  2py-amn2-no1-bnsdap1973  moegua-diphmep-meo-betadcph        2024  me2py-25oxman2-imo-psdab1974  am4py-diphmep-5pho-asppha          2025  bhs-edian2-no2-bnsdap1975  2py-edian2-no1-psdab               2026  bhs-mepipe-emo-glyzdap1976  menim-mepipe-ocho-zdab             2027  cl3pyme-m25thiz-fo-asppha1977  chmhs-2pazin-fo-betainyl           2028  impy-amo2-napo-ibsdap1978  amthiaz-25thizman2-eoco-           2029  ppy-dimephmep-5amo-csdap
  betapy                             2030  chhs-dimen-mes-betapy1979  imhs-amo2-mes-mezphe               2031  hythpym-ams2-ocho-bhsdap1980  amim-ams2-fo-oxal                  2032  bim-thizn-emo-psdap1981  dhim-pymea-men-bphabs              2033  2py-eta-ocho-bsdap1982  2pmhs-din-no2-bhsdap               2034  bz-am3-oem-nbetapy1983  am4py-25thiman2-no1-betadcph       2035  ibhs-mepipen2-pro-zdabs1984  edothpym-ams2-baeo-bnsdap          2036  pippy-dimephmep-no1-mezphe1985  nim-dis-eoco-aspibua               2037  piraz-m25thiz-oem-zdap1986  mepip-edia2-sem-npsdap             2038  cl3pyme-dimephmem-men-aspibua1987  hythpym-pymea-mecpo-glubzla        2039  2py-25thiman2-5pho-betainyl1988  ppy-am3-oem-npsdap                 2040  2py-tridi-napo-dfzdap1989  hythpym-edian2-4pho-glyzdap        2041  dhim-dimephmem-pro-bhsdap1990  amim-24thiman-ocho-betadcph        2042  dmthpym-am3-sem-nzdab1991  imhs-eta-oem-bnsdap                2043  morhs-m25thiz-meo-zdab1992  am2py-mepipe-napo-zorn             2044  pippy-dimen-pyo-mezphe1993  morhs-mepazin-oeto-ibsdap          2045  amim-tetradi-no2-aspibua1994  bim-dimephmem-ocho-betainyl        2046  piraz-m25oxman2-ocho-psdap1995  am2py-pipmea-oem-zdap              2047  me2py-mepipe-mes-bhsdab1996  dhim-pyma2-no2-bhsdab              2048  pippy-diphmem-men-betadcph1997  moegua-ams2-ocho-zdab              2049  phhs-pazi2n-chexo-glyzdap1998  bim-eta-ocho-psdab                 2050  piraz-trias-oem-bphabs1999  impy-edian2-eoco-glubzla           2051  2py-am3-oem-nzdab2000  bimhs-n24thiman-emo-betadcph       2052  n2py-pipa-fo-csdap2001  pyr-eta-5amo-bnsdap                2053  mam2py-24thiz-paco-bhsdab2002  pyrhs-thizn-baeo-psdab             2054  phhs-amn2-mes-betadcph2003  2py-ms-meo-psdap                   2055  mam2py-pazin-napo-bphabs2004  chmhs-ams3-mes-bphabs              2056  bhs-pnymea-mommo-aval2005  cl3pyme-3pazin-emo-psdap           2057  bim-pazin-eoco-bnsdap2006  imhs-amo2-chexo-aspbzla            2058  bimhs-amn3-eoco-glyzdap2007  piraz-pentadi-4amo-ppsdap          2059  me2py-eta2s-5amo-dfzdap2060  hythpym-eta-ocho-bhsdab             2110  dhim-amo2-peo-psdab2061  menim-mepipe-men-zdabs              2111  2pmhs-tetradi-no1-ppsdap2062  am2py-pipmea-oem-bnsdap             2112  2py-dich-5amo-betadcph2063  tolhs-diphmep-fo-glyzdap            2113  hythpym-24thiz-ocho-bsdap2064  bim-24thizman2-men-aspibua          2114  menim-mepipen2-oem-csdap2065  am-pazin-no1-zdabs                  2115  4pmhs-pipa-no1-glyzdap2066  moegua-2pazin-meteto-zdabs          2116  dhim-butn-cpro-zdap2067  impy-24thiz-eoco-betapy             2117  hythpym-am3-sem-nbetameph2068  me-edian2-imo-asppha                2118  bhs-edia2-sem-nzdap2069  mam2py-dimen-imo-glyzdap            2119  edothpym-dis-no2-bphabs2070  mam2py-thizn-imo-betadcph           2120  bimhs-din-meteto-mezphe2071  thpym-dimen-4pho-aspibua            2121  thpym-ams2-ocho-betadcph2072  bim-ams2-5amo-bsdap                 2122  menim-mepazin-eoco-psdab2073  bhs-25oxman2-fo-aspbzla             2123  dhim-tridi-oem-bsdap2074  morhs-props-oem-psdab               2124  pippy-amn2-5amo-asppha2075  phpip-amn2-5amo-bsdap               2125  amim-dis-eoco-bsdap2076  edothpym-2pazin-pro-asppha          2126  thpym-edia2-sem-nbetameph2077  imhs-pnymea-men-betainyl            2127  bim-eta-no1-zdab2078  amim-props-pyo-psdapee              2128  dhim-24thizman2-4amo-asppha2079  2py-mepipe2-sem-nbeta34-            2129  2py-pazin-eoco-bnsdap
  dimeoph                             2130  bim-amn3-paco-bphabs2080  piraz-dio-imo-betainyl              2131  imhs-dimen-no2-psdab2081  bz-amn2-napo-csdap                  2132  cl3pyme-25thiz-eoco-zlys2082  thpym-dimen-no2-bnsdap              2133  npip-diphmep-chexo-csdap2083  amim-butn-ocho-zdabs                2134  dhim-mepipen2-aco-zdab2084  prhs-pipa-nmo-ibsdap                2135  bhs-mepipe-ocho-betapy2085  ec-tridi-napo-bphabs                2136  mam2py-pnymea-oem-mezphe2086  piraz-pipa-oeto-zdabs               2137  dpam-am2-oem-nbetabnaphth2087  menim-thizn-no1-zdab                2138  edothpym-trias-chexo-betainyl2088  thpym-amn2-no1-zdap                 2139  imhs-n24thiman-no2-aspaba2089  me2py-24thiman2-daco-bsdap          2140  nim-pipmes-baeo-mezphe2090  thpym-mepipe-mes-betapy             2141  bhs-amn2-eoco-bnsdap2091  am2py-pyma2-no2-osdap               2142  me-dis-5pho-zdab2092  2py-pazin-mes-dfzdap                2143  bimhs-m25thiz-emo-psdab2093  dmam-diphmem-chexo-zdabs            2144  impy-dimephmem-oeto-csdap2094  pyr-pipa-men-bhsdap                 2145  me2py-din-5pho-zdabs2095  imhs-m25thiz-fo-bnsdap              2146  impy-24thiz-imo-mezphe2096  im-dis-5pho-dfzdap                  2147  am-amo3-no1-glyzdap2097  piraz-24thiman2-imo-betainyl        2148  dhim-am3-sem-npsdap2098  hythpym-diphmem-paco-betainyl       2149  dhim-dis-5amo-psdap2099  phhs-25oxman2-5pho-glupha           2150  2py-mepazin-peo-bhsdap2100  bim-eta-mes-bsdap                   2151  thpym-dis-5amo-aspbzla2101  impy-am3-sem-nbetapy                2152  pippy-dimephmem-5pho-glyzdap2102  bim-24thizman2-no2-aspaba           2153  mepip-mepipe-chexo-psdap2103  me2py-thizn-5pho-glyzdap            2154  dhim-amn2-meto-betainyl2104  amim-dimephmep-5pho-glubzla         2155  bhs-dimephmem-mes-aspbzla2105  bimhs-m25thiz-eoco-betainyl         2156  impy-m25thiz-daco-bsdap2106  piraz-24thizman2-meteto-            2157  bim-thizo-oem-bnsdap
  betapy                              2158  amim-mepipe-nol-betadcph2107  bhs-edian2-meteto-bsdap             2159  bim-25oxman2-napo-bhsdap2108  chmhs-3pazin-no2-zdabs              2160  piraz-dipch-napo-zdap2109  bhs-amn3-emo-dfzdap                 2161  bhs-tridi-paco-betapy2162  mam2py-m25thiman2-chexo-             2213  piraz-pyma2-men-csdap
  betainyl                             2214  imhs-dis-oeto-psdapee2163  chmhs-am3-sem-nbetameph              2215  menim-trias-men-betainyl2164  me2py-pipmeo-no1-zdap                2216  ibhs-diphmem-no2-psdap2165  pippy-m24thiz-daco-betainyl          2217  z-24thiman-no2-betainyl2166  piraz-dimephmep-paco-dfzdap          2218  bhs-eta-emo-asppha2167  mam2py-25oxman2-5pho-aspibua         2219  bhs-propn-cpro-dfzdap2168  bhs-eta-5pho-bhsdap                  2220  bimhs-dimen-chexo-zdabs2169  bim-thizn-eoco-aspbzla               2221  bim-din-mes-tsdap2170  me2py-n2o2n-5amo-bnsdap              2222  dhim-25thiz-napo-bnsdap2171  bim-edia2-sem-nbetapy                2223  dpam-m24thizman2-chexo-bhsdab2172  am2py-din-no1-mezphe                 2224  bimhs-ms-oeto-aspbzla2173  2py-tetras-eoco-bphabs               2225  2py-n2o2n-5pho-aspbzla2174  bimhs-am3diaz-fo-dfzdap              2226  4pmhs-mepipen2-mommo-zdapee2175  dpam-24thizman2-5pho-zdabs           2227  am2py-dimephmep-oem-psdap2176  bimhs-mepipen2-ocho-betapy           2228  bimhs-24thizman2-imo-mezphe2177  bim-edian2-no2-bhsdap                2229  am2py-edia2-sem-nbetameph2178  edothpym-dimephmep-5amo-bsdap        2230  amim-ams2-cpro-aspbzla2179  bzl-ams2-oeto-csdap                  2231  chhs-24thiz-5amo-tsdap2180  tolhs-n2nme2n-chexo-glubzla          2232  ppy-dis-oem-glyzdap2181  impy-pymea-5amo-betadcph             2233  am-dimephmem-napo-tsdap2182  2py-m24thizman2-fo-bhsdap            2234  am2py-diphmem-chexo-psdap2183  amim-pipa-meteto-bsdap               2235  thpym-mepipe-ocho-betapy2184  bhs-25oxman2-no2-aspbzla             2236  npip-butn-ocho-bsdap2185  thpym-pentadi-oeto-bsdap             2237  me2py-diphmem-cno-tsdap2186  me2py-diphmep-daco-psdap             2238  thpym-mepipe-no2-glyzdap2187  bim-edian2-hso-bnsdap                2239  tolhs-mepipen2-imo-psdapee2188  dhim-dimephmem-hso-asppha            2240  amim-diphmep-peo-bsdap2189  pippy-thizn-eoco-oxal                2241  piraz-amn2-5amo-bphabs2190  impy-ms-mes-betapy                   2242  dhim-hexadi-ocho-csdap2191  piraz-edia2-sem-npsdap               2243  hythpym-3diaz-4pho-bhsdab2192  am2py-m25thiz-eoco-aspibua           2244  me2py-diphmem-oem-aval2193  chhs-24thiz-meo-bhsdap               2245  am-mepipen2-eoco-mezphe2194  phhs-mepipen2-peo-oxal               2246  am2py-m25thiz-oem-glyzdap2195  pyrhs-eta-peo-oxal                   2247  imhs-pipa-emo-bsdap2196  piraz-pipa-imo-bnsdap                2248  piraz-trias-aco-bhsdap2197  morhs-din-men-asppha                 2249  bim-trias-chexo-psdab2198  pippy-pentadi-eoco-zdap              2250  deam-mepipen2-no2-aspbzla2199  gua-ams3-daco-zdap                   2251  bim-pnymea-meto-aspbzla2200  bimhs-m25oxman2-emo-zdap             2252  bhs-diaz-aco-zdab2201  nmhs-m24thiz-pro-bphabs              2253  bhs-mepipe-oem-zorn2202  4pmhs-edia2-sem-nbetameph            2254  impy-24thiz-fo-zdabs2203  phpip-diphmem-fo-bphabs              2255  imhs-tetradi-imo-zdap2204  4pmhs-dimen-no2-bhsdap               2256  thpym-edian2-meo-bhsdap2205  bim-eta-oem-zdab                     2257  mam2py-am2-oem-npsdap2206  me2py-eta-chexo-thizzdap             2258  am2py-pymea-no1-aspibua2207  deam-pymea-mes-csdap                 2259  chhs-pipmea-mes-psdap2208  4pmhs-dimephmem-napo-dfzdap          2260  mam2py-tridi-4amo-csdap2209  amim-tridi-napo-aspbzla              2261  imhs-24thizman2-emo-betadcph2210  thpym-n2nme2n-cpro-zdabs             2262  gua-pyma2-chexo-bhsdab2211  thpym-pipa-5amo-csdap                2263  hythpym-amn3-mecpo-tsdap2212  n2py-din-napo-zdab                   2264  bimhs-diphmep-fo-bhsdap2265  bim-eta-5pho-bhsdap                2317  am2py-pymea-eoco-zorn2266  2py-m24thizman2-oem-betapy         2318  am2py-pymea-napo-psdap2267  dhim-thizo-imo-bphabs              2319  pippy-mepazin-emo-psdab2268  menim-dimen-5amo-psdap             2320  bim-diphmem-eoco-betainyl2269  pippy-diphmem-eoco-bhsdap          2321  impy-25oxman2-pyo-betadcph2270  morhs-propn-eoco-aspaba            2322  bim-25oxman2-5pho-psdap2271  2py-pazin-ocho-zdap                2323  bim-diphmep-mes-ppsdap2272  fthpym-thizn-4amo-bsdap            2324  bhs-pazin-eoco-psdab2273  menim-tridi-baeo-bnsdap            2325  me2py-mepipe-nmo-dfzdap2274  hythpym-pymea-oeto-bsdap           2326  prhs-pipa-mecpo-zdab2275  piraz-pipa-oem-psdap               2327  dhim-m25oxman2-ocho-bsdap2276  deam-dimephmem-napo-psdab          2328  hythpym-24thizman2-pro-bnsdap2277  dhim-tetras-cnmo-bnsdap            2329  bhs-24thiz-cpeo-bsdap2278  amim-diaz-chexo-bsdap              2330  imhs-mepipe2-sem-nbetameph2279  imhs-mepipe-ocho-bsdap             2331  z-25thizman2-ocho-aspibua2280  ibhs-24thiz-chexo-psdab            2332  imhs-trias-5amo-bsdap2281  chmhs-din-eoco-bhsdab              2333  thpym-ams2-ocho-glyzdap2282  imhs-eta-oem-zdab                  2334  imhs-pazin-eoco-zdap2283  bhs-n2nme2n-no2-tsdap              2335  ibhs-24thizman2-oem-bsdap2284  amim-pipa-meo-oxal                 2336  bhs-hexadi-men-bphabs2285  2py-m24thiz-mommo-bhsdab           2337  thpym-pipmea-5amo-aspibua2286  2py-pazin-meo-bnsdap               2338  bim-pyma2-men-aspbzla2287  me2py-edian2-meo-zdab              2339  tolhs-amn2-peo-psdap2288  bhs-eta-no2-zdab                   2340  chmhs-m24thiz-imo-zdabs2289  am2py-pipa-mes-aspaba              2341  bim-amn2-no2-zdap2290  amthiaz-edian2-cnmo-bsdap          2342  dhim-diphmep-eoco-betainyl2291  impy-tridi-emo-bhsdab              2343  piraz-edian2-oem-asppha2292  impy-dimephmep-chexo-zdap          2344  bz-pnymea-meto-betapy2293  pippy-propn-mecpo-bnsdap           2345  dhim-dimen-oem-bhsdab2294  dhim-mepipe-emo-zorn               2346  bimhs-trias-meteto-bhsdap2295  hythpym-mepipe-fo-betadcph         2347  me2py-ams2-fo-betainyl2296  2py-24thiz-ocho-betaet             2348  imhs-pentas-cnmo-asppha2297  bimhs-edian2-meo-csdap             2349  ec-pazin-eoco-aspibua2298  2py-25oxman2-no1-mezphe            2350  amim-24thizman2-napo-betapy2299  deam-m24thizman2-eoco-glyzdap      2351  hythpym-dimephmep-no2-zdap2300  imhs-propa2s-no1-aspbzla           2352  am4py-eta-5amo-aspibua2301  pippy-pazin-no1-csdap              2353  bhs-eta-no2-bhsdap2302  bimhs-mepazin-chexo-csdap          2354  imhs-eta-eoco-bhsdap2303  bimhs-dimen-eoco-bhsdap            2355  amim-tetradi-napo-bhsdab2304  me2py-mepipe-men-dfzdap            2356  thpym-edian2-meo-zdap2305  am-amo2-fo-bhsdab                  2357  bim-thizs-hso-zdab2306  impy-24thiz-imo-csdap              2358  thpym-mepipen2-imo-aspbzla2307  piraz-25thiz-oem-csdap             2359  tolhs-pazin-napo-zdab2308  ibhs-indan2-mommo-betapy           2360  tolhs-dimephmem-paco-betadcph2309  morhs-mepipen2-mes-bnsdap          2361  amthiaz-pipmea-5amo-aspibua2310  thpym-mepipe-5pho-zdap             2362  me2py-24thiz-fo-glyzdap2311  bimhs-m24thizman2-oeto-betapy      2363  ppy-din-fo-zdab2312  piraz-dimephmem-imo-bphabs         2364  mam2py-amn2-eoco-csdap2313  imhs-pyma2-imo-aspibua             2365  prhs-thizs-men-zdap2314  imhs-amo2-oem-bnsdap               2366  impy-n24thiman-meo-bhsdap2315  am4py-dis-meo-asppha               2367  amim-trias-pheo-asppha2316  am2py-tridi-pheo-aspibua           2368  me2py-indan2-pyo-psdap2369  bim-mepipe2-sem-npsdap              2420  imhs-mepipe-5pho-psdab2370  bhs-mepipe-oem-betapy               2421  dmam-amo2-meo-zlys2371  nmor-pymea-peo-zdab                 2422  thpym-m24thizman2-chexo-2372  mam2py-pipa-no1-zdab                      betapy2373  2py-pazin-ocho-zdab                 2423  edothpym-trias-fo-bhsdap2374  bim-diaz-napo-osdap                 2424  am2py-pyma2-chexo-dfzdap2375  ibhs-mepipen2-napo-dfzdap           2425  edothpym-edia2-sem-nzdap2376  hythpym-mepipen2-eoco-aspibua       2426  edothpym-tetradi-men-betapy2377  thpym-mepipe-no2-psdab              2427  amim-dimen-mes-psdab2378  impy-mea-no2-bsdap                  2428  nim-pyma2-cnmo-bhsdab2379  amim-dimephmep-no2-psdab            2429  mam2py-2pazin-ocho-betadcph2380  bim-din-pyo-bhsdab                  2430  imhs-pyma2-eoco-glyzdap2381  2py-m25oxman2-no1-psdab             2431  nmor-thizn-hso-bsdap2382  bimhs-25oxman2-5amo-zdabs           2432  me2py-m24oxman2-pheo-zdabs2383  imhs-24thizman2-ocho-bhsdap         2433  impy-mepipen2-eoco-psdapee2384  dmbim-mepazin-cno-oxal              2434  bim-mepipe-no2-zdab2385  impy-25oxman2-emo-ibsdap            2435  am2py-tetradi-ocho-psdap2386  bhs-3pazin-5amo-zdab                2436  dmthpym-25thiz-meo-betainyl2387  amim-m24thizman2-no1-aspibua        2437  imhs-25oxman2-imo-bsdap2388  fthpym-ams2-men-zdabs               2438  piraz-edian2-4pho-bphabs2389  n2py-dich-meo-oxal                  2439  thpym-amn2-meo-zdab2390  amim-24thizman2-oeto-zdabs          2440  thpym-indan2-no2-dfzdap2391  pippy-mepazin-ocho-zdap             2441  am2py-24thiman2-hso-bhsdab2392  thpym-amn2-oem-zdab                 2442  dhim-pymea-meo-betadcph2393  me2py-amo2-pro-bhsdab               2443  bz-pipa-cpeo-bhsdab2394  2py-edian2-5pho-zdap                2444  nim-propn-no2-glyzdap2395  hythpym-pentas-chexo-aspibua        2445  bimhs-pazin-no1-zdab2396  2py-amn2-5pho-bsdap                 2446  impy-thizo-fo-mezphe2397  bim-eta-eoco-bnsdap                 2447  fthpym-pazin-no2-mezphe2398  pippy-thizn-pyo-oxal                2448  pyrhs-pazin-oem-betainyl2399  bim-edian2-no1-zdab                 2449  thpym-2pazin-men-aspbzla2400  bz-m24thizman2-oeto-aspbzla         2450  2py-diphmep-oem-bhsdab2401  amthiaz-24thizman2-baeo-            2451  impy-ams2-5pho-betainyl
   asppha                             2452  piraz-diphmem-napo-psdab2402  chmhs-m25thiman2-imo-aspbzla        2453  imhs-edian2-ocho-bhsdap2403  mam2py-24thizman2-chexo-psdap       2454  bimhs-dich-pro-psdab2404  bim-din-emo-bhsdab                  2455  bim-edian2-ocho-zdap2405  thpym-pazin-eoco-zdap               2456  bim-edia2-sem-nbetameph2406  me2py-eta2s-emo-betapy              2457  mam2py-eta-imo-zdabs2407  am2py-pipa-mes-zorn                 2458  pippy-indan2-chexo-zdabs2408  dhim-thizs-napo-bphabs              2459  piraz-tridi-eoco-glyzdap2409  bimhs-am2-oem-npsdap                2460  pippy-pipa-meo-psdab2410  am2py-m25thiz-daco-bnsdap           2461  bimhs-amo2-emo-aspibua2411  pyr-eta-ocho-betainyl               2462  impy-diphmem-fo-asppha2412  pippy-diphmep-5amo-csdap            2463  am-25thiman2-meto-betainyl2413  am4py-mepazin-fo-psdab              2464  pyraz-m24thiman2-baeo-zdabs2414  4pmhs-diphmem-meto-psdap            2465  imhs-amn2-no1-bhsdap2415  pyr-amn3-hso-zdabs                  2466  hythpym-m25thiz-oem-zdabs2416  prhs-thizn-no2-bsdap                2467  deam-amn3-imo-bsdap2417  mam2py-mea-4amo-psdap               2468  mam2py-mepazin-hso-psdab2418  bimhs-dich-meo-bhsdap               2469  pippy-tridi-napo-dfzdap2419  piraz-dimephmem-cno-bnsdap          2470  hythpym-amn3-ocho-zdabs2471  thpym-pipa-imo-zdap                2523  thpym-diphmep-5pho-zdabs2472  4pmhs-mepipe2-sem-nzdap            2524  imhs-amn2-no1-psdap2473  2py-mepipe-no2-psdab               2525  chmhs-m24thiz-emo-mezphe2474  amim-pipmea-eoco-betadcph          2526  2py-pyma2-no1-zdabs2475  fthpym-amn2-cpro-glyzdap           2527  piraz-pipmes-no2-tsdap2476  nmhs-m24thizman2-men-asppha        2528  hythpym-24thizman2-pheo-2477  hythpym-24thiz-emo-glyzdap               aspibua2478  2py-propa2s-napo-betapy            2529  bimhs-dimephmem-emo-zdabs2479  pyr-din-hso-bsdap                  2530  phhs-dich-5pho-asppha2480  imhs-mepipe-no1-bhsdap             2531  imhs-pazin-ocho-zdab2481  hythpym-thizn-chexo-betainyl       2532  moegua-n2nme2n-oem-zdabs2482  deam-mepazin-imo-bnsdap            2533  bimhs-m24thizman2-5amo-mezphe2483  ibhs-mepipe-4pho-glyzdap           2534  amthiaz-25oxman2-fo-zdap2484  n2py-edian2-no2-tsdap              2535  thpym-24thiman2-no1-aspbzla2485  bhs-m24thizman2-ocho-thizzdap      2536  me2py-pipa-aco-thizzdap2486  pippy-pazin-oem-csdap              2537  bhs-am3diaz-baeo-psdap2487  deam-diphmem-ocho-bhsdap           2538  bhs-eta-no1-aspibua2488  impy-diaz-fo-mezphe                2539  impy-amo2-emo-psdap2489  n2py-mepipe2-sem-npsdap            2540  piraz-diphmep-meo-aspbzla2490  impy-pipmea-no1-psdap              2541  bz-m24thizman2-5pho-psdap2491  thpym-pnymea-men-bsdap             2542  gua-tetradi-no2-glyzdap2492  ibhs-thizs-chexo-csdap             2543  2py-mepipe-no1-betapy2493  bim-pazin-4pho-aspbzla             2544  nmhs-m25thizman2-napo-ppsdap2494  cl3pyme-thizo-5pho-zdap            2545  pyraz-25oxman2-fo-betainyl2495  thpym-m25thizman2-eoco-aval        2546  nmor-pnymea-baeo-csdap2496  bimhs-pazin-meo-aspbzla            2547  me-pnymea-no1-bnsdap2497  bhs-pipmea-oem-zdab                2548  pippy-amo2-men-zdab2498  bim-tetradi-men-zdab               2549  bhs-props-4amo-betaet2499  dpam-24thizman2-peo-csdap          2550  am2py-trias-pyo-bphabs2500  bimhs-pentadi-no1-aval             2551  impy-eta-emo-zlys2501  am2py-pymea-meo-asppha             2552  bim-eta-hso-betapy2502  bhs-edian2-mes-betapy              2553  me2py-mepipen2-emo-zorn2503  amim-amo2-mmen-tsdap               2554  2py-mepipe-meo-bsdap2504  moegua-24thiman-napo-bphabs        2555  imhs-eta-mes-psdab2505  am2py-3pazin-mes-asppha            2556  gua-pazin-fo-psdab2506  mam2py-m24thizman2-no2-zorn        2557  chhs-amn2-meo-osdap2507  nmor-pipa-no1-betapy               2558  2py-mepipe-no2-betapy2508  amim-thizn-ocho-asppha             2559  thpym-eta-oem-betapy2509  bim-mepipe-mes-aspbzla             2560  dhim-thizs-ocho-betainyl2510  2py-amn3-napo-dfzdap               2561  2py-eta-meo-psdap2511  bhs-m25thiman2-no2-csdap           2562  am2py-pazin-no2-zdap2512  impy-propa2s-baeo-zdap             2563  mam2py-mepipen2-chexo-psdab2513  imhs-amn2-oem-bsdap                2564  4pmhs-m24thizman2-aco-2514  nmor-ams2-ocho-betapy                    betainyl2515  am2py-diphmep-chexo-betainyl       2565  hythpym-25oxman2-4pho-ibsdap2516  bhs-amn2-oem-betapy                2566  moegua-dimephmep-emo-zdap2517  hythpym-dimen-paco-psdab           2567  fthpym-tetradi-paco-bsdap2518  bimhs-pipa-5pho-psdap              2568  bimhs-amn2-eoco-aspibua2519  piraz-25thiman2-emo-glyzdap        2569  n2py-amn2-meo-bsdap2520  imhs-amn3-daco-bhsdab              2570  imhs-amo3-men-asppha2521  pyr-thizs-mmen-psdapee             2571  fthpym-25thiz-mes-dfzdap2522  bim-eta-meo-aspibua                2572  chmhs-dimen-paco-bphabs2573  dhim-24thizman2-emo-bsdap           2624  bhs-amn2-mes-bnsdap2574  2py-pipa-pheo-bhsdab                2625  imhs-edian2-ocho-zdap2575  amim-dio-oem-glubzla                2626  pippy-props-mmen-asppha2576  pippy-25oxman2-mes-psdab            2627  amim-pazin-no2-glyzdap2577  am-pipmeo-mecpo-psdab               2628  chhs-ams2-napo-zdap2578  moegua-pipa-fo-psdap                2629  amthiaz-mepipe-5pho-bhsdap2579  amim-amo2-5amo-zdap                 2630  imhs-pazi2n-no2-betapy2580  im-m25thiman2-ocho-betapy           2631  hythpym-thizn-fo-aspibua2581  piraz-pnymea-ocho-psdap             2632  hythpym-mepazin-pro-zdap2582  imhs-eta-ocho-psdap                 2633  thpym-amo2-emo-zlys2583  bimhs-mepipe-oem-bphabs             2634  z-eta-imo-bsdap2584  dmbim-dimen-no1-zdapee              2635  prhs-25thiz-4pho-dfzdap2585  me2py-m24oxman2-no2-bnsdap          2636  amim-dimen-no2-aspbzla2586  mam2py-dimephmem-fo-betainyl        2637  2py-dimephmem-fo-csdap2587  hythpym-25oxman2-emo-zdab           2638  pippy-ams3-5pho-aspbzla2588  bhs-diphmep-5amo-betapy             2639  im-dimephmem-napo-psdap2589  ec-tetradi-chexo-zdab               2640  4pmhs-24oxman2-5amo-dfzdap2590  hythpym-dio-cpro-betapy             2641  piraz-mea2s-no1-zdab2591  tolhs-mepipen2-ocho-mezphe          2642  am2py-pipa-fo-bhsdap2592  bzl-pentadi-mmen-ppsdap             2643  pyr-mepipen2-ocho-zdab2593  am2py-25thizman2-pheo-glyzdap       2644  bhs-24thiman-meo-glyzdap2594  bimhs-m24thizman2-peo-glyzdap       2645  amim-mepipe2-oem-npsdap2595  dmbim-dis-no1-aspbzla               2646  phhs-eta-chexo-betadcph2596  amim-m25thiz-fo-betainyl            2647  bimhs-24thiz-imo-bnsdap2597  bimhs-eta-no2-glyzdap               2648  dmbim-25oxman2-pheo-betapy2598  2py-edian2-mes-zdab                 2649  bimhs-amn3-napo-zdab2599  amim-amn3-chexo-zdabs               2650  dhim-24thizman2-chexo-psdab2600  hythpym-pyma2-ocho-bnsdap           2651  pyrhs-tridi-eoco-betadcph2601  thpym-m24oxman2-no2-asppha          2652  am2py-amn3-imo-zdabs2602  thpym-pnymea-men-betaet             2653  bzl-pazin-emo-zdap2603  pippy-trias-imo-zdab                2654  deam-pyma2-meo-tsdap2604  thpym-amn2-no1-bhsdap               2655  bz-m25thiz-mes-dfzdap2605  dpam-25oxman2-oem-bphabs            2656  4pmhs-3diaz-daco-betadcph2606  ibhs-mepazin-5amo-bhsdab            2657  nmor-edia2-sem-nbetameph2607  tolhs-pentadi-5pho-ibsdap           2658  pippy-propa2s-napo-bhsdap2608  pyrhs-pipa-pro-betainyl             2659  morhs-pipa-5amo-zdap2609  piraz-24thiz-imo-bsdap              2660  pippy-mepipe2-oem-nbetapy2610  impy-pipa-5amo-bnsdap               2661  dpam-pentadi-no2-psdab2611  me2py-props-imo-betadcph            2662  amim-din-ocho-betadcph2612  cl3pyme-diphmep-meo-aspbzla         2663  hythpym-m24thizman2-2613  n2py-diphmep-baeo-zdabs                   ocho-aspbzla2614  ibhs-24oxman2-meo-dfzdap            2664  phpip-dimephmep-fo-ibsdap2615  amim-mepazin-mes-betadcph           2665  imhs-dio-meo-csdap2616  bzl-diphmep-chexo-glyzdap           2666  bhs-pazin-eoco-bsdap2617  pippy-pipa-emo-zdap                 2667  mam2py-dimen-4pho-bphabs2618  imhs-pipa-oem-psdap                 2668  pyrhs-amo2-emo-thizzdap2619  chhs-amo3-mommo-bhsdab              2669  chmhs-dimephmem-oem-bhsdab2620  n2py-din-5amo-betadcph              2670  prhs-thizn-meo-bnsdap2621  hythpym-trias-meto-betadcph         2671  prhs-pipa-eoco-betadcph2622  me2py-mepipe2-sem-nbeta34-          2672  impy-am2-oem-nbetameph
  dimeoph                             2673  thpym-24thizman2-no2-betapy2623  deam-24thiz-4amo-mezphe             2674  impy-din-peo-betadcph2675  nmhs-amo2-napo-thizzdap             2723  amim-m24thizman2-meo-csdap2676  pyraz-dimephmem-5amo-psdab          2724  am-eta-pheo-betapy2677  bimhs-diphmem-men-bhsdap            2725  thpym-mepipe2-oem-nbetab2678  nim-tetradi-5pho-mezphe                   naphth2679  me2py-m24thizman2-cnmo-             2726  piraz-pnymea-eoco-bhsdap
  betadcph                            2727  impy-pipa-napo-aspibua2680  nim-trias-paco-glubzla              2728  bz-diphmep-meo-thizzdap2681  amim-n2nme2n-ocho-betainyl          2729  bim-indan2-meto-psdap2682  bhs-pyma2-mes-bnsdap                2730  me2py-pipa-mmen-aspibua2683  thpym-amn3-imo-aspbzla              2731  impy-pyma2-cnmo-betapy2684  amthiaz-25thizman2-5pho-            2732  me2py-dimephmem-oem-aspibua
  glyzdap                             2733  bhs-edian2-men-zdab2685  thpym-ams2-meteto-aspibua           2734  imhs-edian2-5pho-psdap2686  ibhs-dimen-chexo-osdap              2735  thpym-edian2-ocho-zdab2687  morhs-24oxman2-5amo-psdap           2736  piraz-dis-5pho-betapy2688  hythpym-dio-aco-zdapee              2737  gua-diphmem-emo-bphabs2689  tolhs-tetradi-mmen-aspbzla          2738  hythpym-pazin-5amo-bhsdap2690  phhs-dimephmem-mommo-bphabs         2739  pyrhs-dimephmem-pyo-psdap2691  chhs-pyma2-men-aspbzla              2740  amim-edian2-no2-osdap2692  ec-mepipen2-aco-osdap               2741  me2py-amn2-daco-mezphe2693  n2py-m24thiz-no1-glyzdap            2742  bimhs-m25thiz-chexo-bnsdap2694  z-diphmep-oem-zdabs                 2743  nmhs-butn-chexo-csdap2695  bz-dimen-no1-betainyl               2744  me2py-ams2-5pho-dfzdap2696  thpym-eta-oem-bsdap                 2745  fthpym-dis-meto-bhsdab2697  impy-diphmep-ocho-zdap              2746  pippy-mepipen2-cnmo-psdap2698  dhim-eta-eoco-zdabs                 2747  am4py-m24thizman2-5pho-csdap2699  me2py-amn3-aco-betadcph             2748  bim-24thiman-eoco-betaet2700  bim-ams2-no2-dfzdap                 2749  thpym-amn2-no1-betapy2701  bim-edian2-no1-betainyl             2750  2py-25oxman2-imo-betainyl2702  bimhs-24thizman2-meteto-            2751  pippy-din-emo-bhsdab
  asppha                              2752  dmbim-m24thiz-hso-psdab2703  am2py-am2-sem-nbetabnaphth          2753  amim-dimen-emo-osdap2704  ec-ams2-imo-aspibua                 2754  pippy-m25thizman2-meo-bsdap2705  im-edia2-oem-nbetameph              2755  pippy-25thiman2-paco-zorn2706  impy-hexadi-men-bsdap               2756  dpam-tetradi-eoco-zdap2707  impy-m25oxman2-ocho-psdab           2757  bhs-dis-men-psdap2708  bimhs-pymea-chexo-osdap             2758  edothpym-propn-imo-mezphe2709  me2py-pymea-meo-ppsdap              2759  bim-diphmep-napo-bphabs2710  chmhs-25oxman2-mes-betaet           2760  imhs-am3-oem-nzdab2711  nim-dimephmem-imo-psdab             2761  imhs-24thizman2-mes-zdap2712  hythpym-pazin-no1-betadcph          2762  bhs-24thizman2-chexo-glyzdap2713  am2py-m24thizman2-mes-              2763  amim-trias-meo-bhsdab
  betainyl                            2764  amthiaz-dich-oem-bhsdab2714  am2py-pymea-no1-zdap                2765  pyraz-thizn-oem-betaet2715  dpam-dimen-napo-bsdap               2766  amim-m24thizman2-4pho-aspbzla2716  imhs-dich-imo-mezphe                2767  dpam-pazin-eoco-aspibua2717  ibhs-mepipe-men-bphabs              2768  impy-24thiz-napo-bphabs2718  bimhs-24thizman2-no1-zdabs          2769  2pmhs-dis-no1-betainyl2719  phpip-pipa-cpro-aspibua             2770  dmam-thizn-baeo-bsdap2720  mam2py-pnymea-paco-glubzla          2771  pippy-am2-sem-nzdab2721  dmbim-hexadi-mecpo-psdapee          2772  bimhs-pnymea-baeo-mezphe2722  dmbim-dis-pyo-psdap                 2773  morhs-edian2-cnmo-psdap2774  mam2py-pazin-ocho-betadcph          2825  am-tetradi-baeo-aspbzla2775  nmor-hexadi-no2-psdap               2826  hythpym-pymea-mes-glyzdap2776  chmhs-25oxman2-men-betainyl         2827  bhs-pazin-no2-aval2777  dmam-m24thizman2-ocho-glyzdap       2828  impy-dimephmem-no2-bsdap2778  pippy-dimen-chexo-bhsdab            2829  dhim-mepazin-5pho-zdap2779  thpym-pazin-oem-zdab                2830  piraz-pyma2-5pho-glyzdap2780  bim-24thizman2-paco-zdabs           2831  impy-am2-oem-npsdap2781  morhs-pnymea-pro-betadcph           2832  2py-m25thiz-oem-betadcph2782  me2py-dis-5amo-betapy               2833  pippy-edian2-chexo-betainyl2783  dhim-pipa-men-ppsdap                2834  amim-ams2-mes-asppha2784  nim-din-pro-betapy                  2835  pyraz-dimen-fo-bsdap2785  dmthpym-3pazin-eoco-betapy          2836  fthpym-mepazin-ocho-asppha2786  2py-pazin-eoco-dfzdap               2837  menim-m24thiman2-eoco-zdap2787  dhim-mepazin-meo-bhsdab             2838  piraz-propn-oem-aspaba2788  thpym-din-no2-betainyl              2839  imhs-eta-meo-betapy2789  dmthpym-amn3-aco-zdab               2840  thpym-edian2-no1-zdab2790  deam-m24thizman2-men-dfzdap         2841  piraz-am3-oem-nbetameph2791  bhs-mepipe-4amo-betadcph            2842  hythpym-tetras-pro-bnsdap2792  impy-props-hso-betainyl             2843  am2py-dimen-chexo-glyzdap2793  bhs-amn2-imo-bhsdap                 2844  2py-propa2s-oem-glyzdap2794  pyr-25oxman2-no2-bhsdap             2845  bhs-mepipe-no2-bsdap2795  mam2py-dimen-mommo-psdab            2846  imhs-pazin-oem-zdab2796  npip-eta-aco-bphabs                 2847  dpam-pnymea-no2-psdap2797  bhs-m25thiz-mmen-betainyl           2848  am2py-mepipe2-sem-nbetapy2798  chmhs-mepipe2-oem-nbeta34-          2849  dmam-25oxman2-no2-bhsdap
  dimeoph                             2850  2py-mepipen2-chexo-zdabs2799  bim-ms-no2-betapy                   2851  dpam-25thiman2-peo-mezphe2800  bim-pipa-imo-betadcph               2852  pyraz-24thizman2-emo-bhsdab2801  2py-amo3-cpro-glyzdap               2853  bz-24thiz-chexo-zdab2802  thpym-edian2-no1-zdap               2854  bimhs-24thiz-eoco-tsdap2803  bz-edia2-oem-nzdab                  2855  2pmhs-dis-cpro-thizzdap2804  impy-dimen-men-betadcph             2856  hythpym-din-cpeo-zdab2805  amthiaz-tetradi-ocho-bphabs         2857  2py-pipmeo-5pho-aspibua2806  menim-pipa-oem-psdab                2858  bimhs-m24oxman2-imo-bhsdap2807  thpym-dimen-chexo-bhsdab            2859  bimhs-pymea-chexo-mezphe2808  pippy-24oxman2-emo-oxal             2860  phpip-diphmem-ocho-csdap2809  hythpym-diphmem-meo-mezphe          2861  me2py-25oxman2-oeto-zdap2810  thpym-amn2-mmen-bnsdap              2862  pippy-amo2-imo-bhsdab2811  piraz-ams3-paco-zorn                2863  amim-trias-oem-zdabs2812  pyraz-din-baeo-zdabs                2864  dhim-butn-chexo-bsdap2813  mam2py-dimephmem-oem-zdap           2865  impy-n24thiman-chexo-asppha2814  piraz-25thizman2-no1-tsdap          2866  bhs-pipmes-emo-betainyl2815  nim-25thizman2-imo-aspbzla          2867  imhs-edian2-oem-psdab2816  pippy-mepipe-eoco-aspibua           2868  emnim-pymea-no1-betapy2817  imhs-pyma2-meo-zdap                 2869  thpym-mepipe-mes-bhsdap2818  hythpym-mepazin-imo-psdab           2870  me2py-dimephmep-emo-mezphe2819  hythpym-24thiz-daco-psdab           2871  amim-25thizman2-chexo-oxal2820  2py-m24thiz-5pho-oxal               2872  pippy-24thizman2-5amo-psdab2821  bimhs-eta-hso-mezphe                2873  impy-amn2-4amo-aval2822  2py-eta-5pho-betapy                 2874  imhs-pipmeo-men-dfzdap2823  nmhs-pymea-fo-zdab                  2875  imhs-pymea-ocho-bhsdap2824  mam2py-amn3-oem-mezphe              2876  am4py-tetradi-meo-bhsdab2877  2py-pazin-no2-bnsdap                2928  pippy-amo3-emo-aspibua2878  imhs-dimephmem-oem-zdap             2929  pippy-m25thiz-ocho-zdab2879  ppy-pymea-fo-bsdap                  2930  2py-pazin-no2-zdapee2880  pippy-25oxman2-mommo-zdap           2931  pyraz-pipmeo-cpeo-psdap2881  amim-tetradi-emo-zlys               2932  bimhs-pyma2-5pho-zdab2882  chhs-tridi-no2-zdabs                2933  dhim-m25thiman2-meo-betapy2883  hythpym-amn3-emo-psdap              2934  gua-m25thiz-imo-aspbzla2884  bhs-pazin-oem-betapy                2935  me2py-dimephmem-cnmo-bhsdap2885  hythpym-pipa-imo-bhsdap             2936  me-trias-no2-bsdap2886  piraz-mepipe-men-glyzdap            2937  am-dis-ocho-bphabs2887  piraz-edian2-imo-betapy             2938  bim-tridi-mes-betainyl2888  imhs-dis-pro-betapy                 2939  mepip-trias-fo-bhsdap2889  bzl-edian2-imo-betainyl             2940  am-ams3-cno-csdap2890  chmhs-amn3-cno-bnsdap               2941  piraz-am2-sem-nzdap2891  thpym-trias-cnmo-zorn               2942  z-dimephmem-imo-glyzdap2892  hythpym-ams2-mes-glyzdap            2943  bimhs-diphmem-5amo-betaet2893  dhim-diphmem-emo-betainyl           2944  thpym-pipmeo-5amo-glyzdap2894  imhs-edia2-oem-nbeta34dimeoph       2945  gua-m24thizman2-daco-aspbzla2895  bimhs-m24thiman2-meto-              2946  me2py-dimephmep-4amo-glyzdap
  betainyl                            2947  imhs-mea2s-meo-bhsdab2896  2py-eta-no1-psdab                   2948  imhs-eta-no2-bsdap2897  imhs-edian2-eoco-psdap              2949  mepip-dis-eoco-psdab2898  impy-edia2-oem-nbetapy              2950  amim-mea2s-no2-psdap2899  piraz-hexas-chexo-bsdap             2951  chhs-tetradi-ocho-bnsdap2900  thpym-dis-5amo-zdabs                2952  amim-3diaz-emo-glyzdap2901  impy-din-meto-mezphe                2953  hythpym-mepipen2-aco-zdap2902  piraz-eta-imo-zdabs                 2954  gua-thizn-oem-bhsdab2903  thpym-amn2-meo-bhsdap               2955  mam2py-tetradi-emo-dfzdap2904  dmthpym-amo2-meo-zorn               2956  impy-dimen-meo-dfzdap2905  mam2py-mepazin-chexo-betadcph       2957  impy-n24thiman-oem-psdab2906  hythpym-eta-paco-bnsdap             2958  impy-24thiman2-mes-aspaba2907  pippy-diphmep-mes-bhsdap            2959  dhim-dimen-meo-aspibua2908  pippy-24thiz-hso-glubzla            2960  bim-dimephmem-imo-psdab2909  ec-din-mes-csdap                    2961  pippy-pipmeo-oem-bphabs2910  me2py-dich-chexo-betaet             2962  am2py-tetras-cpro-zorn2911  piraz-pipmea-eoco-zdap              2963  am2py-thizn-cno-bhsdab2912  2py-eta-eoco-bhsdap                 2964  mam2py-24thizman2-cpro-csdap2913  z-diphmep-oem-glyzdap               2965  bim-mepipe-oem-zdap2914  ec-m24thizman2-imo-betapy           2966  pippy-pazin-oem-aspbzla2915  bimhs-amn2-5amo-bnsdap              2967  thpym-pazin-no1-psdab2916  mam2py-trias-mes-csdap              2968  thpym-eta-chexo-betadcph2917  imhs-edian2-ocho-zdab               2969  bzl-amo2-4amo-asppha2918  bhs-mepipe-ocho-zdab                2970  amthiaz-mepipe-no2-csdap2919  piraz-din-5pho-zdap                 2971  bimhs-m24thizman2-2920  me2py-ams2-men-psdapee                    meteto-aspbzla2921  pyrhs-diphmem-imo-bphabs            2972  thpym-diphmem-pyo-mezphe2922  bim-butn-napo-zdapee                2973  ppy-24thiz-eoco-dfzdap2923  bim-edian2-no2-bsdap                2974  hythpym-tridi-chexo-glyzdap2924  bz-pymea-emo-bnsdap                 2975  amim-dimen-5pho-zorn2925  pippy-24thizman2-oem-aspbzla        2976  pippy-pyma2-mmen-thizzdap2926  4pmhs-pyma2-oem-dfzdap              2977  am4py-pyma2-hso-aspbzla2927  bim-diphmep-cpro-glupha             2978  imhs-pazin-5pho-zdab2979  hythpym-diphmep-peo-zdap           3030  piraz-butn-oem-aspbzla2980  bim-mepipe-meo-psdap               3031  thpym-diphmep-oem-bhsdab2981  menim-ams3-baeo-aspibua            3032  dhim-25thizman2-meto-betadcph2982  thpym-edian2-eoco-bnsdap           3033  pippy-tetradi-meto-bhsdap2983  menim-mepipe2-oem-nzdap            3034  am4py-amn3-ocho-asppha2984  phhs-mepazin-chexo-mezphe          3035  morhs-pazin-5amo-glyzdap2985  phhs-25oxman2-meo-betadcph         3036  pippy-24thizman2-mes-zdabs2986  thpym-pazin-meo-bnsdap             3037  dhim-3diaz-5amo-bnsdap2987  chmhs-m25thiz-eoco-betapy          3038  mam2py-25oxman2-cpeo-psdapee2988  mam2py-props-no2-betadcph          3039  bhs-amn2-oem-psdab2989  me-pipmea-meo-aspbzla              3040  hythpym-mepipe-oem-glyzdap2990  bim-ams2-daco-bhsdab               3041  npip-m24thizman2-men-aspbzla2991  dmbim-pipmea-no2-betadcph          3042  dhim-dimephmem-ocho-aspbzla2992  thpym-amn2-ocho-zdap               3043  piraz-thizs-fo-glyzdap2993  dmam-butn-5pho-csdap               3044  pyrhs-thizn-men-zdabs2994  npip-m24thiman2-oem-dfzdap         3045  bim-amo2-mes-thizzdap2995  mam2py-dimephmep-imo-mezphe        3046  deam-edia2-sem-nzdab2996  me-ams2-meo-bhsdab                 3047  mam2py-pipmea-emo-csdap2997  nim-pipa-napo-asppha               3048  prhs-dimephmem-fo-bhsdab2998  bimhs-amo3-napo-bsdap              3049  piraz-m24thizman2-aco-psdab2999  2py-diphmep-4pho-tsdap             3050  imhs-pymea-no2-betainyl3000  me2py-pymea-meo-bhsdab             3051  pippy-am3-sem-nbetabnaphth3001  mam2py-m25thizman2-5pho-           3052  bimhs-pipa-chexo-glubzla
  betapy                             3053  imhs-pazin-oem-betapy3002  bim-tetradi-oem-glubzla            3054  bhs-24thizman2-aco-bhsdap3003  piraz-m24oxman2-ocho-betainyl      3055  am2py-m24thizman2-cpro-aval3004  bim-pazin-oem-zdap                 3056  pyr-25oxman2-napo-glyzdap3005  am2py-25oxman2-oem-ibsdap          3057  imhs-pyma2-oem-mezphe3006  dhim-pymea-imo-bphabs              3058  bhs-24thizman2-emo-bhsdab3007  piraz-pyma2-oem-bhsdap             3059  amim-24thizman2-emo-betainyl3008  dmam-mepipe-5amo-dfzdap            3060  am2py-pymea-emo-zdab3009  bim-amn2-meo-zdap                  3061  amthiaz-tetradi-mes-zdab3010  pyr-din-oem-zdab                   3062  piraz-dimephmem-5amo-csdap3011  bim-edian2-no1-bsdap               3063  ppy-n2o2n-fo-asppha3012  bzl-pazin-meo-bphabs               3064  prhs-25oxman2-chexo-aspibua3013  tolhs-thizn-peo-zdap               3065  am2py-amn2-mecpo-psdab3014  amim-pipmea-mes-bhsdab             3066  bimhs-tridi-5pho-bhsdap3015  dmbim-eta-pheo-oxal                3067  mam2py-m25thiz-ocho-zdabs3016  amim-mepipe-imo-asppha             3068  edothpym-pipa-emo-betapy3017  pyrhs-diphmem-ocho-csdap           3069  imhs-mepipe-no2-betapy3018  imhs-eta-no1-psdap                 3070  pyrhs-edia2-oem-nbetameph3019  z-diphmem-pyo-betadcph             3071  impy-pnymea-no2-betadcph3020  cl3pyme-hexadi-eoco-asppha         3072  amim-diphmem-imo-psdab3021  thpym-ms-eoco-betainyl             3073  dmam-am2-sem-nzdab3022  amim-edia2-oem-nbeta34dimeoph      3074  dmbim-24thiz-fo-aspibua3023  thpym-amo2-eoco-bsdap              3075  am2py-amn2-meo-aspibua3024  am2py-dipch-chexo-csdap            3076  thpym-amm2-no2-bhsdap3025  pippy-m25thiman2-peo-psdap         3077  am4py-pipmea-fo-psdapee3026  mam2py-trias-fo-psdab              3078  am-din-peo-asppha3027  pippy-3pazin-meo-zdab              3079  dhim-edian2-cpeo-betapy3028  gua-din-fo-ibsdap                  3080  piraz-eta-fo-bsdap3029  nmor-dimephmem-oem-dfzdap          3081  ibhs-m25thiz-meo-csdap3082  phhs-edian2-eoco-aspibua             3134  bim-mepazin-fo-osdap3083  imhs-amn2-fo-bhsdap                  3135  pippy-pipa-fo-dfzdap3084  impy-25thiman2-fo-bnsdap             3136  nmhs-diphmem-4pho-mezphe3085  bz-diphmem-mes-zdab                  3137  bhs-amn2-eoco-betapy3086  bim-dimephmep-hso-mezphe             3138  am2py-mepipe2-oem-nbetameph3087  phhs-m24oxman2-5pho-glyzdap          3139  bzl-thizn-5amo-dfzdap3088  2py-pazin-5pho-betapy                3140  pyrhs-mepipe2-oem-nbetapy3089  mam2py-mepazin-oem-zdabs             3141  pippy-amo3-no2-psdap3090  me2py-din-meo-betapy                 3142  me2py-mepipen2-no1-asppha3091  gua-pazin-cnmo-bhsdab                3143  am2py-mepipen2-paco-betainyl3092  imhs-edian2-5pho-bhsdap              3144  me2py-pymea-oem-csdap3093  prhs-am2-oem-nbetabnaphth            3145  tolhs-25oxman2-5amo-zdabs3094  impy-edia2-sem-nbetabnaphth          3146  chhs-dimen-emo-osdap3095  me2py-pipmea-napo-glupha             3147  me2py-diphmem-5amo-dfzdap3096  bimhs-props-emo-psdab                3148  pyrhs-mepipe2-oem-nbetapy3097  bim-mea2s-mes-betapy                 3149  mam2py-pnymea-meto-zdapee3098  dhim-pipmes-meteto-dfzdap            3150  z-m25thiz-meo-psdab3099  me2py-diaz-men-betadcph              3151  me2py-mepazin-oem-psdap3100  dhim-tetradi-emo-zdabs               3152  am4py-pymea-mes-glyzdap3101  bhs-mepipen2-mes-thizzdap            3153  bhs-mepipe-oem-zdap3102  4pmhs-m25thiman2-imo-bhsdab          3154  bhs-eta-meo-zdab3103  z-m24thizman2-mes-aspibua            3155  dmam-tridi-5pho-glupha3104  mam2py-mea2s-pyo-bhsdap              3156  piraz-diphmem-aco-zlys3105  imhs-pyma2-5pho-betapy               3157  bim-pymea-mes-mezphe3106  n2py-m25thizman2-no1-betapy          3158  imhs-mepipe-mes-bhsdap3107  piraz-dimephmem-eoco-betainyl        3159  hythpym-diphmep-meteto-zdap3108  piraz-diphmem-no1-betapy             3160  menim-pipa-daco-psdab3109  prhs-ms-4amo-betadcph                3161  amim-3pazin-eoco-bphabs3110  2py-pipmes-no1-ibsdap                3162  thpym-thizs-emo-bhsdap3111  bim-dimephmep-5pho-bhsdab            3163  npip-24thiz-ocho-dfzdap3112  impy-diphmep-5amo-psdab              3164  am2py-25oxman2-meo-aspbzla3113  bimhs-eta2s-emo-dfzdap               3165  4pmhs-amo2-chexo-aspibua3114  me2py-pymea-men-mezphe               3166  bhs-mepipe-no2-zdab3115  deam-eta-mes-aspibua                 3167  me2py-mepipen2-meo-bhsdab3116  bz-pazin-nmo-zdabs                   3168  imhs-edian2-no2-psdab3117  bhs-pazin-5pho-bnsdap                3169  edothpym-dimephmep-5pho-zdap3118  tolhs-dis-pyo-aspbzla                3170  imhs-pazin-imo-bhsdap3119  bim-pazin-oem-psdab                  3171  bhs-pazin-meo-zdap3120  nmor-pymea-mecpo-bphabs              3172  bhs-n24thiman-ocho-mezphe3121  impy-mepazin-ocho-zdabs              3173  am4py-24thiz-5amo-betainyl3122  am-pipmes-fo-psdab                   3174  bim-eta-5pho-bnsdap3123  fthpym-24thizman2-fo-betapy          3175  bim-mepipe-no1-psdap3124  dhim-pipmes-pro-mezphe               3176  im-m25thiz-meto-ibsdap3125  pippy-mepazin-mmen-betainyl          3177  am2py-25oxman2-4pho-psdab3126  hythpym-pazin-fo-bhsdap              3178  imhs-amn2-5pho-bnsdap3127  2py-m24oxman2-no1-betapy             3179  bimhs-25oxman2-meo-bphabs3128  amim-mepipen2-meto-ppsdap            3180  am-thizn-5pho-bnsdap3129  bhs-mepipe-eoco-psdab                3181  thpym-m24thizman2-mes-zdab3130  am-hexadi-5pho-betainyl              3182  nim-pipmea-men-betadcph3131  z-propa2s-meo-glyzdap                3183  bzl-tridi-meo-aspibua3132  2py-diphmep-emo-bhsdab               3184  amim-ms-chexo-zorn3133  mepip-trias-mes-zdabs                3185  nim-eta2s-napo-bhsdab3186  dhim-amn2-eoco-psdab                3237  me2py-dis-mmen-zlys3187  phpip-m24thizman2-5amo-bphabs       3238  imhs-25oxman2-emo-bhsdab3188  bhs-propa2s-no2-betadcph            3239  dhim-amo2-emo-mezphe3189  thpym-amn2-no1-zdab                 3240  bhs-24thiman-oem-oxal3190  hythpym-ams3-meo-zdabs              3241  mam2py-diphmep-imo-betainyl3191  imhs-edian2-5pho-zdap               3242  dhim-diphmem-oeto-bnsdap3192  hythpym-diphmep-emo-betainyl        3243  bim-3diaz-daco-bhsdap3193  me-pymea-no2-bnsdap                 3244  me2py-mepipen2-eoco-betapy3194  bimhs-am2-sem-nzdap                 3245  ec-24thiz-ocho-ppsdap3195  bim-hexadi-5amo-bhsdap              3246  am2py-mepazin-cpro-psdab3196  imhs-mepipe-mes-bnsdap              3247  nmor-mepipe-4pho-zdap3197  bimhs-amo3-men-bsdap                3248  2py-m24thizman2-aco-zdab3198  hythpym-mepipen2-chexo-             3249  bim-25thiman2-no1-psdab
  betainyl                            3250  pippy-edia2-sem-nzdab3199  mam2py-mepazin-imo-asppha           3251  2py-mepipe-oem-bhsdap3200  bhs-pyma2-meteto-bhsdab             3252  thpym-mepipe-no2-bsdap3201  cl3pyme-am3diaz-no1-betadcph        3253  imhs-25thiz-chexo-glubzla3202  dmthpym-diphmem-emo-betainyl        3254  amim-pnymea-no1-psdap3203  imhs-thizn-no1-bhsdap               3255  pyrhs-eta-mes-zlys3204  imhs-eta-5pho-zdap                  3256  moegua-diphmep-cpeo-betadcph3205  bimhs-dimen-baeo-bnsdap             3257  pyrhs-din-napo-zdap3206  piraz-mepipen2-ocho-zdab            3258  thpym-amo2-men-tsdap3207  thpym-eta-oem-bnsdap                3259  me2py-m25oxman2-meo-zdapee3208  imhs-mepipe-meo-psdab               3260  hythpym-trias-no1-betainyl3209  bimhs-mepazin-cpro-zdabs            3261  bimhs-dimephmem-emo-betainyl3210  dmthpym-mepipe-ocho-zorn            3262  dhim-tetras-5pho-bhsdap3211  thpym-tridi-oeto-aspbzla            3263  am-mepazin-emo-aspaba3212  piraz-24thiz-5pho-zdabs             3264  am2py-amn2-men-betapy3213  npip-m25thiz-mes-zdap               3265  bim-din-meo-aspbzla3214  ec-25thiman2-meo-aspibua            3266  pippy-butn-emo-betadcph3215  amim-tetras-5pho-mezphe             3267  im-pyma2-mommo-psdab3216  pippy-diphmem-men-bphabs            3268  thpym-amn3-men-psdab3217  nim-pipmea-peo-zdab                 3269  am2py-am2-sem-nzdab3218  nim-amo2-imo-dfzdap                 3270  pippy-trias-5pho-glyzdap3219  hythpym-amo2-eoco-aspbzla           3271  hythpym-mepipe-no1-zdab3220  bim-pazin-ocho-betapy               3272  am2py-m25thiz-mes-csdap3221  thpym-pyma2-chexo-zdabs             3273  thpym-pazin-5pho-betapy3222  imhs-mepipe2-oem-nbetapy            3274  ibhs-dio-napo-zdabs3223  imhs-edian2-4pho-zlys               3275  pyrhs-m24oxman2-napo-aspibua3224  prhs-am3diaz-napo-bsdap             3276  bim-eta-5pho-zdab3225  cl3pyme-amo2-pheo-mezphe            3277  bhs-amn2-pro-thizzdap3226  hythpym-hexas-pro-bhsdab            3278  bim-mepipe2-sem-nbetameph3227  thpym-diaz-chexo-dfzdap             3279  me2py-diphmep-imo-zdap3228  edothpym-am2-sem-npsdap             3280  nmhs-m24thizman2-no2-betainyl3229  bimhs-m24thizman2-emo-mezphe        3281  amim-amn3-aco-glyzdap3230  bhs-am2-sem-nbetabnaphth            3282  impy-pnymea-5pho-aspibua3231  emnim-pymea-ocho-dfzdap             3283  2py-props-cpeo-ppsdap3232  bim-24thizman2-napo-betapy          3284  pippy-din-no2-glyzdap3233  bzl-diphmem-no2-bsdap               3285  dhim-25thiz-oeto-aspbzla3234  mam2py-diphmem-meo-mezphe           3286  impy-thizo-4pho-dfzdap3235  4pmhs-amn2-mes-mezphe               3287  mam2py-trias-mecpo-dfzdap3236  thpym-pazin-oem-bnsdap              3288  impy-eta2s-nmo-dfzdap3289  bz-24thizman2-pro-bphabs             3340  imhs-dimephmem-mes-psdap3290  dpam-din-imo-psdab                   3341  piraz-din-chexo-mezphe3291  phhs-24thiz-meo-psdap                3342  impy-butn-5pho-betainyl3292  imhs-25thiz-emo-zdap                 3343  dmthpym-3diaz-pro-mezphe3293  hythpym-diphmem-no1-psdab            3344  piraz-pazin-5pho-dfzdap3294  chhs-mepazin-no1-psdap               3345  bim-trias-no1-ppsdap3295  prhs-edian2-cno-bphabs               3346  mam2py-pipmea-no2-psdap3296  bz-pyma2-5amo-zdap                   3347  imhs-amn2-mes-bhsdap3297  am2py-dich-emo-bsdap                 3348  dpam-25oxman2-chexo-thizzdap3298  pyrhs-pymea-4pho-mezphe              3349  pyrhs-amn2-emo-zdap3299  impy-trias-imo-thizzdap              3350  mam2py-dich-no2-bhsdab3300  dhim-thizn-emo-glyzdap               3351  mam2py-mepipen2-ocho-zdabs3301  thpym-m25thiman2-pheo-bhsdab         3352  n2py-trias-ocho-betapy3302  moegua-amo2-ocho-psdab               3353  me2py-diphmem-baeo-aspbzla3303  chmhs-dimephmem-oem-aspibua          3354  bim-m25thiz-men-betainyl3304  z-n24thiman-men-bnsdap               3355  bz-m24thizman2-emo-betainyl3305  bim-amn2-5pho-bhsdap                 3356  thpym-dimephmem-5pho-psdap3306  ec-m25oxman2-no2-aspbzla             3357  bim-pazin-5pho-bnsdap3307  ec-24thiz-no1-zdabs                  3358  thpym-amn2-5amo-aspaba3308  bim-edian2-no2-glyzdap               3359  deam-ams2-emo-bsdap3309  hythpym-dimephmep-men-betapy         3360  bhs-24thiz-oem-betaet3310  n2py-mepipen2-napo-betapy            3361  2py-eta-oem-bnsdap3311  bhs-mepipe-no1-mezphe                3362  bzl-mepipe-imo-ppsdap3312  bz-dis-eoco-aspaba                   3363  am4py-25thizman2-fo-csdap3313  bimhs-edia2-oem-nbetabnaphth         3364  bzl-24thizman2-cpeo-csdap3314  pippy-diphmep-meo-csdap              3365  mam2py-tetradi-imo-dfzdap3315  chmhs-dimen-fo-zdab                  3366  mam2py-25oxman2-ocho-tsdap3316  piraz-trias-eoco-aspaba              3367  hythpym-dio-oem-dfzdap3317  hythpym-24thizman2-imo-bnsdap        3368  2py-dipch-aco-bhsdab3318  amim-pymea-cpeo-bnsdap               3369  cl3pyme-diphmep-mes-bsdap3319  piraz-din-fo-psdap                   3370  nim-dimephmep-oem-betadcph3320  nim-25thiz-no2-psdab                 3371  emnim-pyma2-oem-betapy3321  bimhs-m24thizman2-imo-zlys           3372  2py-am2-sem-nzdap3322  am2py-mepipe2-oem-nbetab             3373  bhs-amn2-mes-zdap
  naphth                               3374  impy-ms-4amo-betadcph3323  bzl-mepipen2-imo-bnsdap              3375  hythpym-24thiz-no2-zdabs3324  me2py-dis-meo-psdap                  3376  cl3pyme-amn2-ocho-zdab3325  amim-trias-5pho-psdab                3377  z-pazin-5amo-glupha3326  menim-amo2-men-dfzdap                3378  me2py-pyma2-ocho-betadcph3327  hythpym-tridi-mes-bsdap              3379  bimhs-dimephmep-cnmo-bhsdab3328  2py-25oxman2-no1-asppha              3380  mam2py-eta-meo-betaet3329  ec-amn2-chexo-aspbzla                3381  bimhs-diphmem-fo-bphabs3330  prhs-edia2-sem-nbetabnaphth          3382  mam2py-ams3-imo-glyzdap3331  2pmhs-trias-chexo-csdap              3383  mam2py-am3-oem-nbetameph3332  am2py-dis-mommo-bsdap                3384  npip-dis-imo-bhsdap3333  dmbim-din-5amo-csdap                 3385  bhs-24thizman2-imo-betainyl3334  imhs-mepipe-no2-zdab                 3386  2py-diphmem-mes-betainyl3335  4pmhs-edian2-chexo-asppha            3387  bim-diphmem-no1-mezphe3336  hythpym-2pazin-eoco-bhsdap           3388  thpym-pnymea-no2-bhsdap3337  piraz-24thizman2-meo-dfzdap          3389  dhim-thizs-napo-glubzla3338  bhs-mepipe-no1-psdab                 3390  menim-diphmep-meo-tsdap3339  thpym-am3diaz-emo-bnsdap             3391  piraz-pipmes-mes-bhsdab3392  bim-pazin-meo-bnsdap                3444  amim-eta-cno-glyzdap3393  pippy-diphmep-fo-zorn               3445  mam2py-mepipen2-imo-psdap3394  bzl-m25thiman2-napo-glyzdap         3446  dhim-pazin-ocho-dfzdap3395  bim-amn3-emo-glyzdap                3447  imhs-pazin-cno-zdab3396  bhs-24thiz-no1-psdab                3448  gua-propn-eoco-bphabs3397  bim-pazin-no1-betaet                3449  bhs-mepipe-mes-zdap3398  bhs-tetradi-men-aspibua             3450  2py-diphmep-fo-betadcph3399  mam2py-amn3-oem-psdap               3451  im-props-men-betadcph3400  chhs-pipmea-no1-betadcph            3452  impy-ams3-cnmo-zlys3401  piraz-din-chexo-bsdap               3453  n2py-dimephmep-napo-bnsdap3402  menim-din-meto-bhsdap               3454  fthpym-diphmem-pro-psdap3403  emnim-pipmea-napo-bhsdap            3455  me2py-dio-5amo-betainyl3404  impy-pnymea-meo-bnsdap              3456  bim-pipmea-chexo-betadcph3405  imhs-edian2-5pho-zdab               3457  amim-n2o2n-imo-zdab3406  mam2py-am2-sem-nbeta34dimeoph       3458  am2py-thizo-chexo-betainyl3407  me2py-hexas-mes-bphabs              3459  hythpym-pymea-5pho-betaet3408  am2py-amn3-no1-zlys                 3460  bhs-tetradi-eoco-betainyl3409  bimhs-ams2-paco-zdapee              3461  bim-am3-sem-npsdap3410  bimhs-pazin-emo-ibsdap              3462  morhs-tridi-napo-ppsdap3411  imhs-amn2-5pho-psdap                3463  imhs-pentadi-5amo-bhsdap3412  chmhs-pyma2-fo-aspaba               3464  bz-mepipen2-paco-zdabs3413  dhim-dimephmem-5pho-psdap           3465  piraz-tridi-5pho-aspbzla3414  deam-24thiz-ocho-zdap               3466  thpym-edian2-ocho-bsdap3415  bz-pnymea-chexo-bphabs              3467  mam2py-thizn-no2-betapy3416  impy-mepazin-5amo-zdap              3468  hythpym-tetradi-meo-bsdap3417  am2py-pipmea-napo-bnsdap            3469  z-mepipe2-sem-nbetabnaphth3418  me2py-3diaz-pheo-glubzla            3470  thpym-pazin-ocho-psdab3419  piraz-butn-oem-csdap                3471  thpym-25oxman2-fo-glubzla3420  2pmhs-props-no1-betainyl            3472  ppy-diphmep-napo-aspibua3421  2py-dis-oem-betadcph                3473  imhs-mepazin-eoco-aspbzla3422  chhs-thizo-chexo-zorn               3474  imhs-diaz-eoco-betadcph3423  2py-pentas-cpeo-betapy              3475  4pmhs-pyma2-chexo-aspibua3424  am-m25thiz-chexo-glupha             3476  me-3pazin-emo-asppha3425  piraz-25thiman2-hso-bhsdab          3477  bim-amn2-eoco-bsdap3426  hythpym-pipmea-chexo-tsdap          3478  amim-dimephmem-mes-betainyl3427  piraz-dio-emo-csdap                 3479  bimhs-tetradi-imo-glyzdap3428  im-pipmeo-4amo-bphabs               3480  imhs-pipmea-baeo-zdab3429  bim-m25thiz-emo-mezphe              3481  me2py-dimephmem-emo-bsdap3430  amim-pymea-ocho-psdab               3482  impy-pymea-imo-betadcph3431  impy-dimephmep-eoco-csdap           3483  me2py-3pazin-no2-glyzdap3432  ibhs-dis-5pho-betainyl              3484  me-dimen-emo-zdapee3433  dhim-m24thizman2-meo-bhsdab         3485  hythpym-din-napo-aspbzla3434  dmbim-pipmea-imo-glyzdap            3486  thpym-edian2-ocho-bhsdap3435  cl3pyme-eta-napo-bphabs             3487  2py-dimephmem-men-bphabs3436  bhs-eta-ocho-zdap                   3488  piraz-pymea-no1-bphabs3437  bim-pazin-5pho-psdab                3489  bhs-pipmea-pyo-betadcph3438  bhs-pnymea-imo-bsdap                3490  dhim-pyma2-emo-bhsdap3439  chmhs-pymea-meo-zdab                3491  nmhs-thizn-eoco-betadcph3440  piraz-pnymea-oem-zdabs              3492  2py-din-5amo-betainyl3441  chhs-mepipen2-meo-psdab             3493  mam2py-dis-ocho-dfzdap3442  amim-dimen-meto-betainyl            3494  bhs-trias-meo-bphabs3443  hythpym-thizn-mes-psdap             3495  imhs-dimephmep-cpeo-aspibua3496  hythpym-mepipen2-imo-mezphe         3548  hythpym-mepipe-paco-psdab3497  amim-dimen-no2-zdap                 3549  me-trias-5pho-zdabs3498  piraz-dimephmem-pro-dfzdap          3550  amim-tridi-oem-betainyl3499  me2py-trias-ocho-bsdap              3551  prhs-24thiz-ocho-psdap3500  piraz-pymea-4amo-betadcph           3552  am2py-dimephmep-ocho-bnsdap3501  mam2py-n24thiman-5amo-psdab         3553  chmhs-pazin-mes-betaet3502  bim-24thiz-men-glupha               3554  imhs-thizn-5pho-glubzla3503  phpip-dich-imo-bhsdab               3555  bhs-tetras-mes-dfzdap3504  mam2py-m25thizman2-fo-zdap          3556  am2py-mepazin-eoco-mezphe3505  2py-thizn-5pho-zdab                 3557  n2py-dimen-meteto-zlys3506  thpym-pipa-mes-mezphe               3558  dhim-pazin-pro-csdap3507  mam2py-25oxman2-cpeo-bhsdab         3559  am4py-m25oxman2-eoco-dfzdap3508  z-dimephmem-meo-bphabs              3560  am-am2-oem-npsdap3509  amim-24thiz-cno-aspbzla             3561  impy-mea2s-meo-zorn3510  nim-thizn-napo-betapy               3562  am2py-trias-no1-thizzdap3511  dmbim-dimen-meo-zdap                3563  dmthpym-amn2-napo-betapy3512  pyrhs-pymea-baeo-aval               3564  me-dis-pheo-betadcph3513  imhs-edian2-emo-dfzdap              3565  pippy-thizs-peo-bhsdap3514  thpym-mepipe-eoco-bsdap             3566  2py-amn2-no1-zdap3515  2py-dis-no2-betapy                  3567  mam2py-pipmes-napo-aspbzla3516  amim-pipa-nmo-psdapee               3568  piraz-24thiz-napo-psdab3517  bhs-tetras-5amo-betadcph            3569  bim-mepipe-napo-bnsdap3518  am-m25oxman2-ocho-glubzla           3570  bhs-edian2-men-psdap3519  bim-pazin-eoco-psdab                3571  me2py-mepazin-chexo-bhsdab3520  bhs-amn2-no1-bhsdap                 3572  hythpym-eta-emo-bsdap3521  me2py-din-5pho-zdabs                3573  imhs-tetradi-eoco-betapy3522  thpym-mepipen2-oem-glyzdap          3574  nim-24thiman-no1-csdap3523  2py-n2o2n-imo-glyzdap               3575  thpym-eta-meo-psdap3524  hythpym-tetradi-emo-bhsdap          3576  nmor-tridi-men-bsdap3525  dhim-24thizman2-5amo-aspbzla        3577  z-25oxman2-chexo-bhsdap3526  hythpym-pnymea-mes-aspbzla          3578  deam-amo2-no1-zorn3527  bimhs-amn3-napo-glubzla             3579  me-pyma2-meto-asppha3528  bim-pazin-oem-bnsdap                3580  4pmhs-mepazin-oem-aspbzla3529  n2py-m25oxman2-men-bsdap            3581  imhs-diphmep-men-mezphe3530  thpym-mepipe-eoco-zdab              3582  nmor-diphmep-fo-bhsdab3531  me2py-edia2-sem-nbetabnaphth        3583  dhim-dimephmem-men-zdapee3532  mepip-pnymea-mes-psdap              3584  z-ams2-daco-aspibua3533  dpam-25oxman2-5amo-psdab            3585  mepip-eta2s-oem-bphabs3534  thpym-n2nme2n-no2-bhsdab            3586  piraz-edian2-ocho-betaet3535  nmor-amn3-emo-glyzdap               3587  hythpym-pipa-4pho-glyzdap3536  hythpym-25oxman2-fo-betainyl        3588  am2py-tetradi-5amo-zdap3537  hythpym-pyma2-hso-aspibua           3589  pippy-mea2s-imo-glyzdap3538  hythpym-dimephmem-men-tsdap         3590  am2py-mepipen2-no2-zdapee3539  4pmhs-mepazin-imo-bhsdap            3591  2py-eta2s-chexo-zdab3540  impy-tetradi-no1-betaet             3592  2py-edia2-sem-npsdap3541  n2py-diphmep-meo-betaet             3593  bim-eta-no2-bnsdap3542  piraz-pnymea-napo-glyzdap           3594  2py-dimen-5pho-bnsdap3543  imhs-mepipe-eoco-bsdap              3595  am2py-pnymea-pro-bhsdap3544  bhs-dimen-fo-bsdap                  3596  bhs-amn2-oem-bsdap3545  bim-thizo-napo-zlys                 3597  thpym-mepipe-eoco-psdab3546  tolhs-pyma2-5amo-csdap              3598  impy-24thiman2-no1-betainyl3547  am2py-amn2-no2-glubzla              3599  pyr-din-no2-betapy3600  2pmhs-edian2-hso-aspibua            3652  thpym-butn-chexo-bhsdap3601  impy-trias-men-zdab                 3653  im-mepipen2-emo-asppha3602  bim-din-eoco-mezphe                 3654  am4py-24thiz-mmen-zdabs3603  am2py-dimephmem-no1-psdab           3655  dmthpym-dich-ocho-zdab3604  imhs-amn2-ocho-betapy               3656  thpym-amn2-mes-bnsdap3605  piraz-m25thiz-paco-asppha           3657  thpym-24thizman2-no1-betadcph3606  chhs-pipa-nmo-psdab                 3658  2py-pazin-oem-betapy3607  me2py-pipa-aco-zdab                 3659  bim-edian2-no2-psdab3608  impy-dipch-meo-zdab                 3660  bz-mepazin-no1-betainyl3609  bz-edian2-chexo-zdapee              3661  phpip-pnymea-no2-asppha3610  bzl-diphmep-eoco-psdapee            3662  2py-diphmep-mes-zdab3611  amim-ams2-napo-betadcph             3663  amthiaz-dimephmep-paco-bnsdap3612  bimhs-tridi-4amo-mezphe             3664  pippy-edia2-oem-nbeta34-3613  am4py-amo2-emo-betainyl                   dimeoph3614  dhim-pentas-ocho-psdap              3665  me-dimephmem-chexo-bphabs3615  ibhs-m24thiz-oem-aspibua            3666  imhs-dimephmep-emo-bphabs3616  dhim-m24thiz-imo-betainyl           3667  me2py-pipmeo-napo-bnsdap3617  ppy-eta-mes-betainyl                3668  phpip-tridi-imo-bsdap3618  z-dimephmem-no2-bhsdap              3669  bimhs-dich-pro-aspbzla3619  imhs-pazin-no2-bsdap                3670  chhs-eta-oem-zdap3620  thpym-eta2s-fo-bhsdap               3671  amthiaz-trias-oem-csdap3621  piraz-pazin-peo-bnsdap              3672  bimhs-pymea-5pho-glyzdap3622  imhs-eta-no1-bhsdap                 3673  dhim-n24thiman-4amo-csdap3623  me2py-ms-meo-dfzdap                 3674  bhs-tridi-mmen-dfzdap3624  thpym-edian2-oem-bnsdap             3675  imhs-dimephmem-men-psdap3625  mepip-diphmep-hso-bhsdap            3676  bim-pymea-chexo-bnsdap3626  thpym-dimephmep-mes-psdab           3677  pippy-amo2-cnmo-bhsdab3627  bz-24thiz-chexo-glyzdap             3678  mam2py-pymea-imo-psdab3628  ibhs-pyma2-meteto-zdap              3679  dhim-pyma2-meo-aspibua3629  bim-eta-meo-bhsdap                  3680  piraz-ams3-meo-psdapee3630  pippy-din-napo-glyzdap              3681  bz-pyma2-no2-aspbzla3631  bim-24thizman2-hso-zdap             3682  hythpym-amo2-no1-aspaba3632  bim-mepipe-no2-zdap                 3683  am4py-am2-oem-nbetameph3633  bimhs-pipa-chexo-zdab               3684  me2py-m25thiz-fo-mezphe3634  thpym-m25thiz-meo-psdap             3685  bz-24thiz-4pho-bhsdab3635  am-tridi-ocho-glyzdap               3686  imhs-amo2-no1-psdap3636  am-dis-men-zdap                     3687  nmhs-diphmep-chexo-betapy3637  bhs-ams3-oem-psdab                  3688  thpym-eta-imo-betainyl3638  hythpym-pipa-men-psdap              3689  bzl-ms-oem-bhsdap3639  amim-25thiz-men-zdapee              3690  impy-mepipe-cno-glubzla3640  imhs-24thiz-ocho-glyzdap            3691  thpym-tridi-eoco-zdap3641  hythpym-ms-meo-bphabs               3692  impy-butn-eoco-bnsdap3642  me-amn2-emo-dfzdap                  3693  amim-pnymea-5amo-psdab3643  bim-amo2-eoco-bphabs                3694  bim-m25thiz-napo-asppha3644  bim-mepipe-no1-zdab                 3695  ppy-dimephmem-ocho-dfzdap3645  dhim-dimephmem-nmo-bphabs           3696  me2py-amo2-5amo-thizzdap3646  amim-mepipe-oem-csdap               3697  pippy-m25thiman2-meteto-3647  dhim-hexas-peo-betapy                     betadcph3648  chmhs-dimephmem-imo-zorn            3698  thpym-amn2-mes-zdap3649  dhim-mea-eoco-zlys                  3699  amim-amn3-cpeo-asppha3650  me2py-propa2s-eoco-aspibua          3700  imhs-tetradi-no1-bhsdap3651  mam2py-pipmes-cpeo-dfzdap           3701  bimhs-edia2-oem-npsdap3702  thpym-props-emo-csdap                 3754  dmthpym-ams2-cpeo-psdap3703  piraz-tridi-oem-psdap                 3755  imhs-dimephmem-eoco-psdap3704  z-diaz-emo-betadcph                   3756  pyrhs-mepazin-oem-csdap3705  bhs-eta-no2-bsdap                     3757  dhim-din-ocho-asppha3706  n2py-m25thizman2-mes-bsdap            3758  me2py-mea-chexo-zdab3707  bim-eta-imo-bsdap                     3759  bzl-am2-sem-nbetameph3708  2py-amn2-oem-bhsdap                   3760  amthiaz-amo2-meo-bsdap3709  me2py-dimephmem-imo-dfzdap            3761  bim-tetradi-eoco-aspbzla3710  imhs-diphmep-imo-asppha               3762  am2py-thizn-cpro-csdap3711  bimhs-edia2-oem-nzdab                 3763  pippy-diphmep-fo-aspaba3712  deam-pyma2-imo-mezphe                 3764  chhs-m25thiz-ocho-bphabs3713  cl3pyme-thizn-men-bnsdap              3765  imhs-m24thizman2-no1-glyzdap3714  imhs-edian2-ocho-betapy               3766  bhs-2pazin-no2-psdap3715  edothpym-amo3-imo-zorn                3767  4pmhs-diphmep-cnmo-betainyl3716  bim-pipmea-mecpo-glyzdap              3768  piraz-mepipe-5pho-betapy3717  imhs-m24thizman2-5amo-bsdap           3769  amim-tetras-emo-psdab3718  bim-pazin-oem-zdab                    3770  am2py-thizn-mes-zdab3719  hythpym-tetradi-oeto-betainyl         3771  thpym-am2-oem-nzdap3720  morhs-amo2-ocho-tsdap                 3772  thpym-amn2-ocho-bsdap3721  ppy-pyma2-5amo-aspibua                3773  impy-m24thizman2-men-bphabs3722  imhs-amn2-eoco-psdab                  3774  am-propa2s-imo-csdap3723  im-25oxman2-5pho-asppha               3775  hythpym-diphmem-mecpo-zdap3724  pippy-25oxman2-fo-aspibua             3776  dpam-mepipe-4pho-bhsdap3725  piraz-diphmem-no2-aspibua             3777  amim-ams2-nmo-betapy3726  bz-24thizman2-pyo-betadcph            3778  2pmhs-edian2-5pho-bhsdab3727  amim-dimen-mes-csdap                  3779  imhs-pazin-no2-bnsdap3728  dhim-pipa-chexo-zdap                  3780  am-m25oxman2-mes-glyzdap3729  menim-n2o2n-pyo-csdap                 3781  amthiaz-diphmem-oem-aspibua3730  thpym-hexadi-mommo-oxal               3782  nmhs-diphmep-eoco-psdap3731  am2py-dich-fo-bhsdap                  3783  piraz-24thizman2-men-psdap3732  imhs-eta-no1-zdab                     3784  2py-edian2-mes-bnsdap3733  bhs-24thiman-mes-betapy               3785  nim-24thiz-fo-betapy3734  gua-amn3-pyo-aspbzla                  3786  bimhs-ams2-pyo-psdap3735  me2py-m24thizman2-5pho-bsdap          3787  fthpym-hexas-cnmo-betainyl3736  nmor-am3-oem-nbetameph                3788  pyrhs-amo3-mes-betadcph3737  2py-am3-oem-nzdap                     3789  bhs-tridi-oem-mezphe3738  imhs-din-mmen-zdab                    3790  mepip-butn-hso-asppha3739  bimhs-edian2-mmen-bsdap               3791  impy-ams2-meo-mezphe3740  cl3pyme-edian2-napo-asppha            3792  im-24thizman2-emo-bnsdap3741  am4py-dis-fo-aspaba                   3793  pyraz-tetras-5pho-csdap3742  pyraz-tridi-no1-psdap                 3794  nmor-mepipe-emo-glubzla3743  thpym-m25thiman2-chexo-zdab           3795  pyraz-ms-emo-betainyl3744  am2py-amo2-5amo-asppha                3796  moegua-m24thizman2-3745  am2py-amn2-nmo-aval                         eoco-bhsdab3746  dmthpym-thizs-napo-bphabs             3797  menim-eta-oeto-aspibua3747  am2py-dimephmep-aco-dfzdap            3798  imhs-edian2-eoco-psdab3748  bim-pazin-no1-bsdap                   3799  thpym-propa2s-cpro-zdap3749  edothpym-amn3-oem-ppsdap              3800  bzl-pymea-men-bnsdap3750  z-amo2-pro-bphabs                     3801  piraz-din-no2-bhsdap3751  impy-mepipe-nmo-asppha                3802  fthpym-tetradi-eoco-betapy3752  dmam-mepipe-ocho-bnsdap               3803  amim-pnymea-meo-psdapee3753  2py-mepipe-no1-psdap                  3804  thpym-m24thiman2-men-aspaba3805  imhs-24thiman2-pheo-aspibua         3857  npip-pentadi-5amo-csdap3806  am2py-pymea-no2-dfzdap              3858  2py-eta-eoco-zdab3807  amim-eta-meo-asppha                 3859  bhs-mepazin-oem-betadcph3808  bimhs-pentadi-mes-aspibua           3860  hythpym-pazin-fo-bphabs3809  bim-pazin-oem-bhsdap                3861  thpym-dimephmem-emo-zdap3810  fthpym-3pazin-imo-zorn              3862  bim-mepipe-oeto-csdap3811  me2py-propa2s-eoco-psdap            3863  am2py-pazi2n-ocho-betapy3812  bzl-pymea-oeto-zdapee               3864  bzl-mepipen2-eoco-bphabs3813  phhs-mepipe2-oem-nbetabnaphth       3865  2py-amn2-eoco-mezphe3814  am2py-edian2-5pho-bhsdap            3866  impy-mepipe-no1-bsdap3815  bhs-amn2-no1-zdap                   3867  bim-edian2-no1-bsdap3816  hythpym-tridi-5amo-aspibua          3868  hythpym-m24thizman2-ocho-3817  ec-pipmea-ocho-glyzdap                    aspibua3818  bim-edian2-5pho-aspibua             3869  2py-dimephmep-chexo-zdabs3819  impy-pymea-4amo-betapy              3870  2py-amn3-eoco-bhsdab3820  am2py-m25thiman2-meo-tsdap          3871  mam2py-25thiman2-mes-betainyl3821  hythpym-ms-napo-psdap               3872  bimhs-dimephmep-mecpo-betaet3822  imhs-pnymea-emo-glyzdap             3873  hythpym-24oxman2-meo-glyzdap3823  amim-amn2-chexo-bhsdab              3874  mam2py-tridi-napo-asppha3824  imhs-edian2-mes-bhsdap              3875  im-24thiz-meo-zlys3825  2py-hexadi-meo-dfzdap               3876  am2py-pipa-no1-mezphe3826  ibhs-ams3-nmo-asppha                3877  amim-m25thizman2-imo-bnsdap3827  piraz-amn2-chexo-psdapee            3878  am2py-pymea-men-asppha3828  am2py-24thizman2-nmo-aspbzla        3879  bhs-amn2-eoco-bsdap3829  bim-am3-oem-nbetapy                 3880  piraz-mepipen2-ocho-bhsdab3830  thpym-mepipe-meo-aspbzla            3881  bimhs-24thizman2-pyo-betainyl3831  bhs-eta-ocho-psdab                  3882  am4py-tridi-emo-aval3832  imhs-amn2-ocho-psdap                3883  morhs-pazin-napo-aspibua3833  bhs-m24thizman2-pro-glyzdap         3884  bimhs-24thiz-emo-bhsdap3834  moegua-pymea-mes-ibsdap             3885  piraz-dimen-napo-psdap3835  bhs-mepipe2-oem-nbetabnaphth        3886  nmor-mepipe-cno-aspaba3836  nmor-ams2-5pho-aspaba               3887  edothpym-am3-sem-nbeta34-3837  hythpym-mepipe2-oem-nbetameph             dimeoph3838  bhs-edian2-mes-psdap                3888  2py-n2o2n-no2-zdabs3839  pippy-pazin-chexo-asppha            3889  deam-dis-no1-bphabs3840  imhs-25thizman2-mes-betadcph        3890  bim-mepipe-5pho-zdap3841  chhs-diphmem-napo-thizzdap          3891  bimhs-din-5amo-bsdap3842  impy-amn3-meo-bphabs                3892  2py-mepipe-eoco-psdap3843  chhs-mepipe-men-glyzdap             3893  2py-pazin-no2-zdab3844  am2py-pazin-mes-bphabs              3894  amim-mepipe-mes-psdap3845  thpym-amn2-mes-psdab                3895  phpip-pymea-oem-bhsdap3846  2py-edian2-chexo-bsdap              3896  bim-hexadi-5pho-betainyl3847  2py-amo2-5pho-bnsdap                3897  dhim-pyma2-ocho-bsdap3848  n2py-m24thiz-meto-glyzdap           3898  thpym-ams2-ocho-psdap3849  bim-amn2-ocho-bhsdap                3899  am-pentas-eoco-csdap3850  piraz-din-eoco-tsdap                3900  bhs-24thiz-meo-glupha3851  bim-24thiman-cpeo-zorn              3901  n2py-amn3-meo-osdap3852  am2py-diphmep-cnmo-glyzdap          3902  mepip-m24oxman2-men-aspibua3853  pyraz-tetradi-mommo-asppha          3903  emnim-dimephmem-5pho-psdab3854  pippy-ams2-baeo-betapy              3904  gua-m24thizman2-no1-psdap3855  chmhs-am2-oem-nbetabnaphth          3905  imhs-edian2-mes-betapy3856  impy-dimephmep-napo-bnsdap          3906  hythpym-mepazin-ocho-bhsdab3907  imhs-pazin-meo-bhsdap              3959  dhim-3diaz-fo-zdap3908  bim-edian2-eoco-glupha             3960  imhs-mepipe-no1-bsdap3909  dmthpym-pipa-imo-asppha            3961  piraz-pipmea-chexo-glyzdap3910  pippy-pipmea-no2-aspbzla           3962  bim-eta-no1-betapy3911  am2py-pnymea-napo-bhsdap           3963  bhs-amn2-no1-zdab3912  dhim-mepipe2-sem-nbetapy           3964  bim-pipmea-pro-bnsdap3913  nmor-pazin-chexo-dfzdap            3965  2pmhs-mepipe2-oem-nbetapy3914  morhs-din-ocho-betainyl            3966  2py-eta-no1-zdab3915  dmbim-propn-5amo-zdapee            3967  hythpym-24thizman2-emo-zdabs3916  imhs-amn3-cno-betadcph             3968  bhs-edian2-oem-zdap3917  morhs-pnymea-cpeo-bhsdap           3969  dhim-mepipe2-oem-nbetapy3918  nmhs-ams2-men-glyzdap              3970  pippy-m25oxman2-men-dfzdap3919  hythpym-amn3-imo-asppha            3971  moegua-pipa-ocho-ibsdap3920  tolhs-pymea-5pho-dfzdap            3972  deam-trias-eoco-csdap3921  mam2py-diphmep-eoco-glyzdap        3973  am2py-2pazin-napo-aspbzla3922  impy-indan2-no2-aspbzla            3974  thpym-edian2-eoco-bhsdap3923  dpam-25thiman2-daco-zlys           3975  dhim-dimephmem-no2-bhsdab3924  2py-pipa-cnmo-betainyl             3976  me2py-25oxman2-emo-ibsdap3925  bhs-eta-no2-zdap                   3977  dpam-m25thiz-4amo-zdab3926  thpym-pnymea-men-zdab              3978  dhim-pymea-imo-glyzdap3927  dhim-pyma2-4amo-bsdap              3979  mam2py-pentas-fo-asppha3928  2py-pymea-meo-bsdap                3980  2pmhs-25thiz-mes-bhsdap3929  emnim-dimephmem-men-psdab          3981  bhs-mepazin-men-mezphe3930  amim-edia2-oem-nbetabnaphth        3982  dhim-pazin-mes-asppha3931  me2py-amn2-eoco-thizzdap           3983  tolhs-pipmes-napo-dfzdap3932  thpym-pyma2-cpeo-betadcph          3984  bhs-thizo-mes-psdap3933  me2py-25oxman2-no2-oxal            3985  pippy-edian2-eoco-bhsdab3934  2py-m24thizman2-cnmo-bphabs        3986  piraz-dis-oem-bphabs3935  imhs-props-fo-betainyl             3987  thpym-pazin-mes-bhsdap3936  me-dipch-no1-bphabs                3988  imhs-edian2-ocho-psdab3937  z-dimen-no1-bnsdap                 3989  ibhs-mepipe-mes-psdab3938  pippy-mepipen2-mmen-asppha         3990  hythpym-indan2-chexo-dfzdap3939  bhs-m24thiz-chexo-zdap             3991  phpip-tetras-eoco-zdabs3940  ec-pipmea-men-zdab                 3992  piraz-mepipe-meo-betadcph3941  chmhs-pipmeo-5pho-bhsdap           3993  hythpym-m25thiz-aco-oxal3942  thpym-eta-mes-bsdap                3994  mam2py-tridi-no2-bphabs3943  bhs-dimen-men-zdap                 3995  ppy-diphmem-4amo-asppha3944  impy-m24thizman2-meo-zdab          3996  am-amo2-emo-psdap3945  pyr-edia2-oem-npsdap               3997  imhs-m24thiz-meo-zdabs3946  prhs-mea-emo-zdab                  3998  me2py-amo2-no1-csdap3947  2py-mepipe-ocho-zdap               3999  am2py-pnymea-5pho-aspbzla3948  me2py-eta-aco-betadcph             4000  menim-pnymea-eoco-bnsdap3949  dmbim-mepazin-mecpo-bhsdap         4001  menim-edian2-napo-mezphe3950  amim-pymea-no2-zdap                4002  hythpym-25oxman2-mecpo-csdap3951  imhs-24thizman2-emo-betainyl       4003  imhs-pymea-napo-betadcph3952  pyr-hexadi-imo-glyzdap             4004  impy-24thiz-4amo-oxal3953  am2py-mepipen2-no2-ibsdap          4005  dhim-dis-no2-betapy3954  edothpym-trias-ocho-zdap           4006  bim-pazin-mes-bsdap3955  chmhs-2pazin-napo-psdab            4007  prhs-pnymea-ocho-psdap3956  bim-pazin-ocho-zdab                4008  hythpym-trias-eoco-betainyl3957  pippy-m24oxman2-eoco-psdab         4009  bim-mepipe-meo-psdab3958  thpym-pazin-no2-psdap              4010  me2py-n2o2n-chexo-betainyl4011  emnim-pipmea-5amo-betainyl          4063  imhs-mepipe-meo-betapy4012  menim-thizn-oem-psdap               4064  imhs-edian2-5pho-bsdap4013  dhim-3pazin-ocho-psdap              4065  am2py-propn-fo-bsdap4014  gua-edian2-mes-osdap                4066  mam2py-24thizman2-4015  bim-mepipe-5pho-betapy                    chexo-bnsdap4016  am2py-dimephmep-fo-bsdap            4067  2py-pazin-5pho-bnsdap4017  thpym-pipmes-mes-csdap              4068  bhs-eta-no1-psdap4018  pyrhs-24thiz-ocho-glyzdap           4069  nmhs-pipmea-meo-asppha4019  thpym-edian2-5pho-zdab              4070  impy-dis-napo-betadcph4020  imhs-dimephmem-ocho-betainyl        4071  imhs-edian2-oem-zdap4021  nim-trias-napo-glyzdap              4072  dmthpym-tetradi-fo-bhsdab4022  dhim-am3diaz-5pho-glupha            4073  imhs-mepipen2-chexo-dfzdap4023  menim-tridi-5amo-bhsdap             4074  cl3pyme-din-emo-aspibua4024  ec-diphmep-no1-bhsdab               4075  2py-pazin-5pho-psdab4025  moegua-amo2-oem-ibsdap              4076  am4py-m24oxman2-chexo-mezphe4026  mam2py-m24thizman2-men-csdap        4077  emnim-tetradi-oem-betapy4027  amthiaz-pazin-ocho-aspaba           4078  bim-m25thiz-pyo-glyzdap4028  dmthpym-mepipe2-oem-nzdab           4079  imhs-n2nme2n-eoco-thizzdap4029  pyr-tetradi-no2-glubzla             4080  cl3pyme-diphmem-emo-bsdap4030  impy-pymea-chexo-csdap              4081  mam2py-m25thiman2-men-glyzdap4031  am4py-din-5amo-zdap                 4082  prhs-pipmes-cpeo-bhsdap4032  amim-amn3-emo-zdab                  4083  bhs-mepipe-mes-bsdap4033  dhim-pipmea-chexo-asppha            4084  amim-mepipe-napo-zdap4034  bim-pipmea-meo-zdab                 4085  pippy-ams2-hso-zdap4035  bhs-mea2s-paco-zdabs                4086  dmam-edian2-ocho-mezphe4036  me2py-mepipen2-mes-betapy           4087  imhs-mepipe-no1-betapy4037  piraz-amn2-mes-dfzdap               4088  hythpym-2pazin-men-betapy4038  imhs-amn2-ocho-zdab                 4089  imhs-eta-meo-asppha4039  imhs-pazin-no2-zdap                 4090  mam2py-pymea-mes-betadcph4040  bim-25oxman2-ocho-aspbzla           4091  impy-pipmea-no2-mezphe4041  impy-tetradi-peo-bhsdab             4092  am2py-dimephmep-chexo-aspbzla4042  bhs-24thizman2-imo-betadcph         4093  thpym-pazin-fo-zdap4043  pyrhs-pnymea-4pho-bhsdap            4094  am2py-24thizman2-pyo-zlys4044  thpym-m25thiz-oem-aspibua           4095  bimhs-tridi-cpro-bnsdap4045  deam-dis-no2-aspaba                 4096  amim-m24thizman2-ocho-4046  amim-hexadi-peo-bsdap                     betainyl4047  thpym-m24thiz-ocho-csdap            4097  amthiaz-tridi-mmen-psdap4048  pyraz-m24thiz-cpro-psdab            4098  phhs-mepipe2-oem-nzdap4049  bim-amn2-oem-dfzdap                 4099  npip-pipmeo-meo-zdab4050  imhs-am3diaz-ocho-betadcph          4100  thpym-amn2-meo-betapy4051  2py-mepipen2-mes-ibsdap             4101  bhs-pazin-eoco-zdap4052  bimhs-amo2-eoco-csdap               4102  bimhs-dimephmem-aco-glyzdap4053  n2py-diphmem-5pho-bhsdap            4103  nmor-trias-5pho-psdab4054  bimhs-pazin-baeo-psdap              4104  bim-mepipe2-sem-nbeta34-4055  2py-trias-mecpo-psdab                     dimeoph4056  pyr-dimephmem-fo-asppha             4105  am2py-thizn-5amo-ppsdap4057  hythpym-dimen-pyo-betadcph          4106  phhs-ams2-chexo-bnsdap4058  mam2py-pyma2-ocho-zdabs             4107  mam2py-24thiman-5pho-psdab4059  me2py-dipch-ocho-zdab               4108  imhs-thizn-mes-aspibua4060  bhs-diphmem-5pho-psdapee            4109  dmthpym-24thiz-eoco-glyzdap4061  dhim-diphmep-mes-zdap               4110  bzl-indan2-oem-mezphe4062  pyraz-m25thiz-pheo-aspibua          4111  ppy-amo2-men-glupha4112  hythpym-trias-oem-zdapee            4164  bhs-eta-no1-bhsdap4113  n2py-ann2-imo-betapy                4165  amim-m25thiz-men-zdabs4114  bimhs-m24thiman2-men-zdabs          4166  bhs-amn2-5pho-psdab4115  2py-mepipe-ocho-zdab                4167  dhim-diphmep-napo-asppha4116  amim-eta-napo-zdap                  4168  z-amn3-napo-asppha4117  pippy-pazin-chexo-asppha            4169  amim-m25thiman2-napo-dfzdap4118  bimhs-amn2-men-zdab                 4170  deam-3pazin-5amo-asppha4119  am2py-pentas-emo-aval               4171  menim-eta2s-meo-asppha4120  impy-tetradi-pyo-aval               4172  im-eta-emo-psdab4121  pyrhs-dich-emo-psdapee              4173  bhs-amn2-meo-betapy4122  amim-dipch-ocho-csdap               4174  ppy-ams2-cnmo-glubzla4123  hythpym-din-fo-bsdap                4175  bhs-m25thiz-pheo-zdap4124  hythpym-thizn-emo-aspaba            4176  dhim-mepipe-men-bnsdap4125  amim-thizn-no1-betapy               4177  deam-2pazin-peo-asppha4126  amim-mepipe-mes-psdab               4178  am2py-amo2-pyo-aspibua4127  dhim-tetradi-5amo-bhsdab            4179  dmthpym-am3-oem-npsdap4128  dhim-pipa-emo-betainyl              4180  piraz-din-pheo-bhsdap4129  2pmhs-pipa-fo-psdap                 4181  dmam-diphmep-eoco-glyzdap4130  bim-pazin-no1-psdab                 4182  amim-din-nmo-betapy4131  mam2py-diphmep-meo-betapy           4183  moegua-24thiz-emo-betainyl4132  dmam-amn3-oem-zdabs                 4184  impy-diphmem-imo-bphabs4133  me2py-24thizman2-emo-zdab           4185  hythpym-pentadi-no2-dfzdap4134  impy-m24thizman2-aco-betapy         4186  4pmhs-tridi-imo-betaet4135  dmam-24thizman2-5pho-zdabs          4187  2py-amn3-men-bhsdab4136  bhs-mepipe-meo-zdab                 4188  chmhs-pazin-5pho-zorn4137  piraz-trias-oem-aval                4189  piraz-pazin-eoco-glyzdap4138  2py-edia2-sem-nbetapy               4190  emnim-pnymea-no2-bsdap4139  piraz-m24thizman2-meo-bhsdab        4191  thpym-eta-oem-zdap4140  am2py-eta-fo-thizzdap               4192  dmam-mepazin-no1-bnsdap4141  pippy-24thizman2-5amo-zdabs         4193  me2py-amn2-ocho-betainyl4142  pippy-mepazin-imo-betapy            4194  imhs-amn2-oem-betadcph4143  hythpym-edian2-eoco-zdapee          4195  am2py-m25thiz-5pho-zdab4144  moegua-tridi-5amo-aspbzla           4196  2py-pymea-imo-zdap4145  deam-n2o2n-eoco-bsdap               4197  bz-din-cno-zdab4146  thpym-din-no1-bhsdap                4198  bimhs-edian2-oem-zorn4147  2py-edian2-mes-psdap                4199  mam2py-25thizman2-eoco-mezphe4148  hythpym-dipch-5pho-csdap            4200  me2py-thizn-4pho-glupha4149  imhs-mepipe-eoco-zdap               4201  hythpym-pazin-emo-ppsdap4150  ppy-25thiz-napo-aspaba              4202  imhs-thizn-meto-betadcph4151  me2py-pipmea-emo-glyzdap            4203  me2py-mepipe-ocho-psdap4152  hythpym-m25thiz-cnmo-mezphe         4204  impy-amn2-meo-dfzdap4153  bimhs-m24thizman2-emo-psdap         4205  dmbim-mepipe2-sem-nbetab4154  2py-dipch-5pho-csdap                      naphth4155  fthpym-dimen-pyo-glyzdap            4206  bhs-dis-men-betadcph4156  phpip-dimephmem-pro-mezphe          4207  am2py-pipa-5pho-bnsdap4157  amim-pnymea-eoco-bphabs             4208  me2py-n2o2n-4amo-betadcph4158  pippy-24thiz-chexo-zdab             4209  bim-pazi2n-eoco-glyzdap4159  mam2py-amn2-napo-bnsdap             4210  dhim-pyma2-eoco-psdab4160  piraz-edian2-meo-bhsdab             4211  imhs-amo2-5pho-zlys4161  hythpym-ams2-ocho-zorn              4212  dhim-edian2-oeto-betainyl4162  thpym-thizo-meo-psdap               4213  2pmhs-mepipe-meto-bnsdap4163  chmhs-dis-5amo-bsdap                4214  me2py-pipmea-daco-aspbzla4215  pyr-am2-oem-nbeta34dimeoph          4266  bimhs-amn3-oem-betadcph4216  moegua-mepipe-no1-bphabs            4267  mam2py-edian2-meo-psdab4217  hythpym-pyma2-fo-betainyl           4268  imhs-mepipen2-5pho-psdap4218  me2py-ams2-5pho-betapy              4269  mam2py-amn3-meo-csdap4219  im-dis-imo-aspibua                  4270  2py-eta2s-no1-bhsdab4220  2py-24thizman2-men-zdapee           4271  impy-mepazin-imo-mezphe4221  ibhs-24thiz-oem-dfzdap              4272  ibhs-thizo-ocho-betapy4222  nmhs-ams3-emo-bhsdap                4273  bim-din-no2-zdap4223  npip-pipmeo-imo-dfzdap              4274  piraz-trias-mes-zdap4224  mam2py-amo2-meteto-betainyl         4275  imhs-mepazin-eoco-zorn4225  am2py-pentas-emo-bsdap              4276  bim-pipmeo-men-zdap4226  bhs-m25thiz-fo-glupha               4277  bim-dimephmem-pyo-betainyl4227  phpip-pnymea-eoco-betainyl          4278  dmam-eta-men-zdabs4228  piraz-amn3-oem-bhsdab               4279  amthiaz-eta-5pho-betainyl4229  bim-tetradi-daco-psdab              4280  chmhs-dis-fo-dfzdap4230  2py-diaz-5pho-psdap                 4281  mam2py-thizo-5amo-zdab4231  piraz-tridi-meto-zdabs              4282  bim-pipmea-imo-bnsdap4232  thpym-mepipe-ocho-bnsdap            4283  hythpym-n2o2n-no1-aspibua4233  hythpym-25oxman2-chexo-psdab        4284  hythpym-mepazin-men-betainyl4234  bim-m25thiz-oem-asppha              4285  nim-diphmem-eoco-zdap4235  emnim-amn2-no2-asppha               4286  mam2py-pyma2-4amo-bnsdap4236  pippy-am3-oem-nbetapy               4287  moegua-dis-mmen-bhsdab4237  amim-dimephmem-emo-psdap            4288  me2py-mepipen2-napo-csdap4238  2py-3diaz-fo-zdap                   4289  2py-tetradi-no2-zdap4239  bimhs-dimen-men-zdapee              4290  cl3pyme-n2nme2n-emo-aspbzla4240  impy-m25oxman2-cnmo-betadcph        4291  ppy-tridi-mecpo-bhsdap4241  am2py-ams2-5pho-bsdap               4292  dhim-tetradi-imo-glyzdap4242  2py-edian2-oem-bnsdap               4293  bim-tridi-no1-bhsdab4243  am2py-tridi-ocho-psdap              4294  chhs-pymea-emo-bhsdab4244  pyraz-24thiz-no2-asppha             4295  2py-amn2-oem-psdab4245  thpym-trias-imo-bnsdap              4296  imhs-edian2-eoco-zdab4246  mepip-pipmeo-fo-bnsdap              4297  2py-m24thizman2-fo-zdab4247  dmbim-amn2-nmo-csdap                4298  ec-mepipen2-no1-dfzdap4248  gua-pazin-no2-betadcph              4299  bim-edian2-fo-aspbzla4249  2py-amn2-baeo-aspibua               4300  pyr-trias-ocho-bhsdab4250  am2py-hexadi-men-csdap              4301  npip-am3diaz-oem-psdab4251  phhs-dipch-imo-bnsdap               4302  thpym-mepipe-5pho-bnsdap4252  imhs-pyma2-pheo-bnsdap              4303  bim-m24thizman2-oem-aval4253  npip-amn3-oem-bnsdap                4304  bzl-dich-emo-psdab4254  2py-edian2-oem-betapy               4305  mam2py-thizo-chexo-aspibua4255  nmor-24thiz-meto-psdap              4306  2py-thizn-oeto-psdap4256  ec-props-oem-zdab                   4307  thpym-24thizman2-mes-csdap4257  2pmhs-mepipe-oem-betainyl           4308  piraz-eta-oem-mezphe4258  phpip-trias-no2-zlys                4309  bhs-mepipe-mes-psdab4259  thpym-thizn-no2-bphabs              4310  bhs-eta-eoco-psdap4260  pippy-pipmea-emo-betapy             4311  thpym-pnymea-5amo-psdap4261  hythpym-dimephmep-emo-              4312  edothpym-n2nme2n-napo-psdab
  betainyl                            4313  me-pymea-chexo-asppha4262  me2py-dimephmep-napo-betadcph       4314  mam2py-dimephmem-no1-bhsdab4263  thpym-pnymea-5pho-ppsdap            4315  me-diphmep-oem-zdapee4264  deam-25thiman2-napo-bhsdap          4316  imhs-eta-mes-psdap4265  imhs-pazin-meo-bsdap                4317  am2py-amo2-meo-osdap4318  fthpym-m24thizman2-napo-osdap        4370  edothpym-amn2-ocho-bphabs4319  pyrhs-mea2s-fo-psdap                 4371  2py-diphmep-oem-psdap4320  me-25oxman2-5amo-aval                4372  bhs-eta-meo-bnsdap4321  am2py-pyma2-mes-csdap                4373  bimhs-pnymea-meo-bhsdab4322  bim-amn2-5pho-bsdap                  4374  impy-pazin-eoco-psdap4323  thpym-ams3-eoco-zdap                 4375  pyr-24oxman2-ocho-csdap4324  imhs-am2-sem-nbetameph               4376  2py-diphmep-men-betainyl4325  bhs-25oxman2-men-psdapee             4377  bimhs-dimephmep-emo-bhsdab4326  mam2py-25thizman2-eoco-asppha        4378  tolhs-tetradi-meo-zdap4327  imhs-pipmea-5pho-aspbzla             4379  bim-mepipe2-sem-nbetameph4328  dmam-pyma2-no2-glubzla               4380  imhs-amn2-no1-zdap4329  gua-ams3-no1-zlys                    4381  2py-pnymea-men-mezphe4330  im-pazin-emo-bnsdap                  4382  nmhs-24thiman-emo-aspaba4331  bim-pazin-mes-bnsdap                 4383  z-pnymea-fo-csdap4332  me2py-pazin-5amo-glyzdap             4384  thpym-edian2-oem-bsdap4333  bimhs-mepipe2-oem-nbetameph          4385  imhs-mepazin-ocho-bhsdab4334  piraz-trias-cpro-betainyl            4386  dhim-mepazin-mommo-glyzdap4335  bim-tetras-5amo-glyzdap              4387  thpym-amn2-no1-bsdap4336  me2py-m25thiman2-chexo-tsdap         4388  am4py-props-nmo-zdabs4337  imhs-eta-eoco-psdap                  4389  imhs-2pazin-eoco-zdab4338  prhs-ams2-pheo-zdap                  4390  phpip-24thizman2-eoco-aspibua4339  amim-tetradi-fo-zdab                 4391  me2py-m24thizman2-aco-ibsdap4340  bim-amn2-peo-bnsdap                  4392  2py-edian2-eoco-psdab4341  dhim-dimen-no1-zlys                  4393  impy-pymea-ocho-zdabs4342  dhim-thizn-5pho-asppha               4394  2pmhs-dimen-mes-bphabs4343  dhim-amo2-pheo-dfzdap                4395  piraz-amn3-eoco-zdabs4344  me2py-din-no1-aspbzla                4396  pyrhs-m25oxman2-chexo-oxal4345  bim-pyma2-5amo-aspibua               4397  pyrhs-pazin-meo-betadcph4346  dhim-pipa-chexo-mezphe               4398  mam2py-dipch-ocho-bhsdap4347  4pmhs-mepipen2-4amo-psdap            4399  piraz-ams2-men-dfzdap4348  mam2py-mepazin-mommo-aspibua         4400  pyr-diaz-fo-osdap4349  pyr-dis-fo-mezphe                    4401  z-tridi-5pho-bphabs4350  dhim-ams2-oem-dfzdap                 4402  thpym-edian2-ocho-bnsdap4351  mam2py-n24thiman-fo-csdap            4403  piraz-pnymea-ocho-glupha4352  piraz-tridi-hso-zdabs                4404  imhs-diphmep-5amo-bhsdap4353  edothpym-eta2s-emo-dfzdap            4405  me2py-dimephmem-chexo-aspibua4354  bim-m24thizman2-mes-bphabs           4406  hythpym-amn3-men-zdab4355  dpam-dimen-imo-bphabs                4407  thpym-mea2s-no2-bsdap4356  pippy-din-pro-betainyl               4408  bhs-am3diaz-eoco-bphabs4357  2pmhs-dis-fo-bhsdab                  4409  bim-mepazin-meo-zdap4358  edothpym-pazin-fo-betadcph           4410  npip-pipmea-no2-dfzdap4359  impy-2pazin-mmen-betadcph            4411  amim-pazin-cpeo-mezphe4360  am2py-hexas-pro-dfzdap               4412  bimhs-amo2-no1-psdap4361  2py-am3-sem-npsdap                   4413  pyr-am2-sem-nzdap4362  morhs-dio-no2-aspbzla                4414  emnim-amo2-5amo-zdap4363  2py-thizn-5amo-glyzdap               4415  imhs-24thizman2-meo-betadcph4364  mam2py-pyma2-meto-betapy             4416  bimhs-dimephmep-peo-betadcph4365  ibhs-amo2-meo-bphabs                 4417  amim-din-5pho-zdab4366  pyraz-tetradi-imo-bhsdap             4418  me-thizn-chexo-bhsdab4367  thpym-din-oem-zdap                   4419  bhs-pipa-oem-betadcph4368  nmhs-din-meto-betadcph               4420  piraz-pipa-pyo-aspaba4369  me2py-hexas-peo-oxal                 4421  bhs-ata-5pho-zdap4422  2pmhs-tetras-meteto-tsdap           4474  me2py-m25oxman2-meo-bhsdab4423  bim-pazin-ocho-zdap                 4475  hythpym-m25thiz-ocho-betadcph4424  am2py-trias-oem-psdab               4476  dmbim-dimephmem-chexo-psdab4425  bimhs-pipa-men-dfzdap               4477  mam2py-pyma2-chexo-csdap4426  piraz-pazin-mes-aspbzla             4478  prhs-pnymea-chexo-zdap4427  pippy-pipmea-5pho-bsdap             4479  bim-amn2-5pho-psdab4428  bhs-edian2-fo-bsdap                 4480  bimhs-dimen-ocho-betapy4429  ibhs-am3-oem-nzdap                  4481  emnim-am3-oem-npsdap4430  nim-eta-eoco-mezphe                 4482  imhs-amn2-ocho-bsdap4431  am2py-pymea-oem-betadcph            4483  imhs-diphmep-meo-psdap4432  impy-trias-imo-betainyl             4484  am2py-am3-oem-nzdab4433  phpip-m24thizman2-men-asppha        4485  phhs-24thiman-5amo-bphabs4434  impy-amn2-no1-bhsdab                4486  piraz-mepipen2-eoco-bhsdap4435  gua-mepipen2-mes-aspaba             4487  impy-24thiz-no2-aspaba4436  nmor-eta-no2-bhsdap                 4488  bzl-propa2s-emo-csdap4437  me2py-tridi-pro-thizzdap            4489  bim-amn2-meo-zlys4438  bzl-mepipe2-oem-nbetabnaphth        4490  bimhs-trias-baeo-bphabs4439  2pmhs-mepipen2-no1-betapy           4491  piraz-dimephmep-5amo-bsdap4440  amim-diphmem-eoco-zdabs             4492  am4py-mepazin-no1-aspibua4441  impy-amn3-mecpo-zdapee              4493  thpym-diphmep-emo-betapy4442  amim-mepipe-men-betapy              4494  2py-pipa-napo-zdap4443  dhim-pymea-emo-psdab                4495  am2py-dimephmep-ocho-bphabs4444  2py-25oxman2-pro-betapy             4496  amim-mepazin-no1-psdap4445  bimhs-m25thiman2-no2-mezphe         4497  menim-dimen-meo-asppha4446  amim-24thiz-aco-zdab                4498  me-pnymea-eoco-zdab4447  fthpym-trias-5pho-zdab              4499  mam2py-ams2-chexo-betapy4448  dmthpym-mea-oem-dfzdap              4500  bim-edian2-oem-zdap4449  2pmhs-pymea-ocho-zdabs              4501  am2py-pazin-nmo-bphabs4450  imhs-amn2-5pho-psdab                4502  me2py-pazi2n-mes-asppha4451  thpym-pipmea-no2-bhsdab             4503  dmthpym-pipa-5amo-zdap4452  bim-eta-oem-mezphe                  4504  mam2py-edian2-imo-bhsdab4453  thpym-dimen-meo-psdap               4505  thpym-mepipe2-sem-nzdap4454  dhim-m24thizman2-5amo-csdap         4506  im-dimephmem-cno-betaet4455  am4py-pazin-chexo-zdabs             4507  mam2py-pipmeo-no2-bphabs4456  mam2py-3diaz-oem-aspibua            4508  thpym-24thizman2-daco-zdap4457  moegua-mepazin-eoco-bsdap           4509  amim-diphmep-chexo-bhsdab4458  piraz-24thiz-napo-dfzdap            4510  pippy-m25thiman2-5pho-csdap4459  edothpym-pazi2n-ocho-betainyl       4511  impy-pipmea-imo-aspibua4460  me-diphmep-chexo-bhsdab             4512  bim-amn2-ocho-psdap4461  me2py-24thizman2-eoco-mezphe        4513  hythpym-eta-mecpo-zdabs4462  imhs-amn2-no1-bsdap                 4514  2py-eta-no2-zdab4463  bimhs-tridi-no2-psdab               4515  bimhs-dimephmep-5amo-bphabs4464  mam2py-trias-pyo-bnsdap             4516  amim-amn3-no1-bphabs4465  chhs-tetras-eoco-aspibua            4517  mam2py-pymea-oem-bphabs4466  thpym-pipmea-oeto-dfzdap            4518  me-amo2-pheo-aspbzla4467  impy-25oxman2-mmen-betadcph         4519  am2py-diphmem-ocho-bhsdap4468  imhs-edian2-mes-betapy              4520  am2py-ams2-oem-bhsdap4469  npip-tetras-4pho-bhsdap             4521  nmor-mepazin-imo-ppsdap4470  thpym-thizn-men-dfzdap              4522  2py-edian2-meo-psdap4471  im-diphmem-imo-betainyl             4523  thpym-pazin-5pho-zdap4472  emnim-pipmea-ocho-asppha            4524  npip-mepipe-paco-aspbzla4473  edothpym-ams2-men-zdap              4525  pippy-amn3-oeto-oxal4526  nmhs-m25oxman2-5pho-asppha          4578  n2py-mepipe2-sem-nzdap4527  am2py-mepazin-fo-betadcph           4579  bz-propa2s-no2-osdap4528  thpym-tetras-fo-betainyl            4580  2py-edian2-no1-psdap4529  piraz-tridi-ocho-betadcph           4581  bimhs-thizs-eoco-tsdap4530  pippy-trias-fo-bhsdap               4582  nim-mepazin-meo-dfzdap4531  chhs-edian2-peo-bphabs              4583  amim-m25thiz-emo-betadcph4532  phhs-pyma2-meo-bhsdab               4584  morhs-tridi-imo-bsdap4533  deam-25oxman2-ocho-psdab            4585  bimhs-amo3-men-psdab4534  amim-ams2-oem-aspbzla               4586  mam2py-din-nmo-bphabs4535  dhim-pyma2-oem-betainyl             4587  bimhs-24oxman2-no2-bphabs4536  imhs-mepipe-meo-zdap                4588  thpym-pazin-mes-zdab4537  piraz-din-fo-bsdap                  4589  bhs-eta-mes-bsdap4538  2py-eta-oem-psdab                   4590  pippy-amn2-emo-aspbzla4539  piraz-trias-5amo-psdab              4591  moegua-pnymea-men-betadcph4540  amim-pyma2-meo-betadcph             4592  2py-24thiman-cno-bhsdab4541  4pmhs-pentadi-mecpo-psdap           4593  dhim-diaz-meo-bsdap4542  2py-pazin-eoco-betapy               4594  bhs-pazin-no2-zdap4543  imhs-m24oxman2-imo-dfzdap           4595  bim-pnymea-imo-zdab4544  amim-25thiman2-oem-aspibua          4596  deam-hexadi-emo-aspibua4545  npip-m24thizman2-imo-dfzdap         4597  npip-24thizman2-men-betapy4546  hythpym-mepipe-eoco-bnsdap          4598  dhim-24thiman-no2-betapy4547  pyrhs-pipmeo-ocho-bhsdap            4599  ec-ams2-no2-betadcph4548  bim-24thiz-5amo-betainyl            4600  bim-mepipen2-no2-betainyl4549  me2py-pazin-napo-glyzdap            4601  bim-dich-emo-zorn4550  nmor-dimephmem-no1-asppha           4602  bz-24thizman2-fo-betadcph4551  ibhs-am3-oem-nzdab                  4603  imhs-mepipe-oem-bnsdap4552  dmthpym-mepipe-5amo-zdabs           4604  amthiaz-pazin-ocho-zdabs4553  impy-dis-pheo-betapy                4605  bhs-butn-oem-thizzdap4554  me2py-pipmea-mes-bnsdap             4606  2py-eta-ocho-zdap4555  pyraz-dimephmem-no1-aspbzla         4607  npip-dimephmep-mes-psdap4556  imhs-mepipe-oem-bhsdap              4608  2py-mepipe-5amo-bphabs4557  emnim-dimephmep-pro-mezphe          4609  ppy-propa2s-imo-glyzdap4558  am-diphmep-eoco-psdab               4610  mam2py-indan2-emo-zorn4559  am2py-pentadi-imo-bsdap             4611  me2py-m25thiz-ocho-psdab4560  2py-pazin-oem-zdap                  4612  2py-tridi-chexo-psdab4561  imhs-indan2-no1-aspbzla             4613  tolhs-25oxman2-imo-csdap4562  4pmhs-diphmem-hso-aspbzla           4614  imhs-din-cpro-psdab4563  impy-edian2-no1-betainyl            4615  z-dimen-4amo-glyzdap4564  menim-mepipe2-sem-nbetameph         4616  thpym-pnymea-chexo-dfzdap4565  emnim-amo3-no1-glyzdap              4617  am-tridi-5pho-betaet4566  hythpym-pipa-napo-bnsdap            4618  bim-25thiz-baeo-tsdap4567  phhs-tetras-5amo-glyzdap            4619  mam2py-dich-emo-bphabs4568  bim-mepipen2-ocho-bsdap             4620  nmor-edian2-men-bnsdap4569  phhs-25oxman2-men-ibsdap            4621  tolhs-diphmem-emo-csdap4570  dhim-tridi-mes-asppha               4622  2py-edian2-no2-zdab4571  am-pymea-baeo-dfzdap                4623  imhs-amn2-oem-bhsdap4572  2py-mepipe-eoco-bhsdap              4624  mam2py-indan2-meo-psdap4573  moegua-indan2-napo-bnsdap           4625  pyr-dimen-men-psdab4574  impy-n2o2n-emo-osdap                4626  imhs-mepipe-eoco-bhsdap4575  tolhs-dipch-oem-asppha              4627  bim-mepipe-mes-psdab4576  pyr-m25oxman2-cpro-betapy           4628  amim-pnymea-4pho-csdap4577  bz-n2nme2n-fo-oxal                  4629  me2py-amn2-emo-bhsdab4630  gua-dimephmem-daco-asppha           4682  me2py-25oxman2-5amo-psdapee4631  deam-24thizman2-fo-ibsdap           4683  chhs-trias-eoco-betainyl4632  ppy-25oxman2-ocho-bhsdab            4684  nim-mepipe-cno-bhsdap4633  bhs-m25thiz-chexo-psdab             4685  thpym-din-5pho-betaet4634  4pmhs-25oxman2-imo-aspibua          4686  2py-tetradi-imo-bphabs4635  bhs-mepipe-oem-psdab                4687  dhim-dis-ocho-aspibua4636  2py-dimephmem-5amo-dfzdap           4688  impy-mepazin-men-dfzdap4637  bim-eta-emo-bhsdab                  4689  2py-dipch-no2-tsdap4638  tolhs-3diaz-cno-zdab                4690  bim-pyma2-5amo-betadcph4639  am2py-24thiz-mecpo-zdab             4691  im-pymea-fo-bhsdap4640  bhs-diphmep-mes-betadcph            4692  bhs-24thiz-napo-zdabs4641  am2py-am3-sem-nzdap                 4693  pyr-dimephmem-eoco-asppha4642  n2py-thizo-men-aspibua              4694  morhs-24thiman-daco-bhsdap4643  mam2py-tridi-fo-psdab               4695  2py-amn2-men-oxal4644  2pmhs-24thiman-napo-thizzdap        4696  im-dimephmep-5pho-aspbzla4645  mam2py-ams2-no2-aspbzla             4697  mam2py-am2-oem-nbeta34dimeoph4646  bim-tridi-eoco-betapy               4698  cl3pyme-24thizman2-mecpo-4647  morhs-pipmea-imo-mezphe                   betapy4648  piraz-m25thizman2-pyo-bphabs        4699  nim-amo3-men-aspbzla4649  piraz-edia2-sem-nzdap               4700  bim-edian2-5pho-bhsdap4650  imhs-pazin-eoco-bnsdap              4701  mam2py-pipa-4amo-ppsdap4651  z-dimephmem-5pho-betadcph           4702  2py-amn2-mes-betapy4652  dhim-pnymea-oem-psdap               4703  2py-ams2-meo-bhsdab4653  bhs-amn2-no1-psdap                  4704  me-diphmep-imo-bhsdap4654  thpym-mepipe-meo-bhsdap             4705  4pmhs-m25thiman2-5amo-bphabs4655  mam2py-ms-oeto-betadcph             4706  2py-edian2-meo-bnsdap4656  moegua-mepazin-pro-bhsdab           4707  dhim-n2nme2n-baeo-betaet4657  imhs-diphmem-oem-betadcph           4708  thpym-amn2-oem-zdap4658  2py-pazin-ocho-bsdap                4709  pippy-thizo-fo-dfzdap4659  bhs-24thiz-pro-psdapee              4710  dhim-24thizman2-emo-psdab4660  am2py-m24thizman2-ocho-ibsdap       4711  tolhs-din-pheo-aspbzla4661  thpym-dimephmep-no1-zdap            4712  piraz-amo2-5pho-aspbzla4662  hythpym-pazin-meo-betainyl          4713  bhs-diaz-mommo-glyzdap4663  thpym-eta-5pho-betapy               4714  pyr-m25thiz-pyo-aspbzla4664  imhs-24thizman2-5pho-csdap          4715  morhs-dimephmem-emo-psdapee4665  amim-pipmea-cno-bnsdap              4716  hythpym-pymea-meo-zdabs4666  am4py-pnymea-5pho-bhsdab            4717  pyrhs-pipmea-daco-bphabs4667  bim-ams2-no1-psdap                  4718  me2py-am3-sem-npsdap4668  mam2py-24thiz-no1-aspibua           4719  me2py-mepipen2-no1-betapy4669  pippy-3pazin-chexo-bsdap            4720  2pmhs-ams2-fo-oxal4670  amim-dimen-daco-betainyl            4721  thpym-24thiz-ocho-osdap4671  bim-thizn-meteto-zdabs              4722  bim-edian2-pheo-mezphe4672  bhs-pymea-meo-oxal                  4723  thpym-pentadi-meo-betapy4673  me2py-pentas-5amo-psdap             4724  bhs-25oxman2-meo-mezphe4674  bim-pazin-emo-bhsdab                4725  me2py-edia2-oem-nbetapy4675  bhs-pazin-ocho-bnsdap               4726  am-diphmep-no1-psdab4676  thpym-tridi-baeo-zdap               4727  hythpym-thizn-meo-aspibua4677  morhs-tridi-eoco-bnsdap             4728  amthiaz-dis-meto-csdap4678  impy-amn3-mecpo-bhsdab              4729  imhs-tridi-no1-betainyl4679  edothpym-mepipen2-eoco-aspaba       4730  gua-amn2-5amo-betainyl4680  am2py-trias-5pho-betaet             4731  bimhs-eta2s-oeto-dfzdap4681  pippy-dimephmep-oem-bsdap           4732  4pmhs-25thiman2-men-betapy4733  bimhs-25oxman2-oem-aspaba            4784  imhs-24thiz-meo-bnsdap4734  mam2py-tetradi-oeto-zdab             4785  me2py-pazin-no2-aspibua4735  bim-trias-fo-psdap                   4786  me2py-mepipe-no2-zdab4736  z-amo3-5amo-zdab                     4787  me2py-trias-meo-aspibua4737  n2py-dimephmep-napo-zdabs            4788  imhs-edian2-meo-zdab4738  bim-amn2-emo-betadcph                4789  me2py-24thiz-imo-bnsdap4739  fthpym-mepazin-emo-bnsdap            4790  bim-eta-meo-bnsdap4740  me2py-dich-no2-psdab                 4791  am4py-thizn-meo-aspbzla4741  pippy-amo2-meo-asppha                4792  2py-edian2-no2-zdap4742  bimhs-pnymea-mommo-glupha            4793  amthiaz-mepipen2-5pho-zdab4743  dhim-dimephmep-oem-zdap              4794  am2py-24thizman2-eoco-psdapee4744  piraz-24thiz-imo-betadcph            4795  am2py-tridi-fo-bsdap4745  2py-diphmep-no2-betadcph             4796  imhs-amn2-fo-ppsdap4746  dpam-thizo-imo-mezphe                4797  bimhs-dimen-5pho-bphabs4747  2pmhs-dipch-5amo-glyzdap             4798  amim-eta-napo-dfzdap4748  imhs-3diaz-fo-aspibua                4799  bim-eta-no2-psdab4749  bhs-24thizman2-4amo-aspbzla          4800  thpym-amn2-5pho-bsdap4750  impy-ams2-imo-bhsdab                 4801  thpym-dimen-pheo-psdap4751  dhim-diphmem-pro-bsdap               4802  amim-m24thiman2-eoco-bnsdap4752  mepip-m24thizman2-oem-psdap          4803  bhs-am3diaz-men-zdab4753  bimhs-24thizman2-mecpo-              4804  thpym-edian2-5pho-bsdap
  glyzdap                              4805  imhs-tetradi-imo-betainyl4754  chhs-dis-mes-betadcph                4806  4pmhs-edia2-oem-nbeta34-4755  impy-n2nme2n-daco-zdap                     dimeoph4756  dhim-mepipe2-oem-nzdab               4807  amthiaz-25oxman2-fo-psdab4757  menim-pymea-chexo-glyzdap            4808  imhs-dimen-mes-zdabs4758  cl3pyme-pyma2-no1-betainyl           4809  moegua-dimephmep-napo-zdabs4759  piraz-amn3-cpro-bnsdap               4810  2py-dimephmep-no2-psdap4760  imhs-mepipen2-no1-glupha             4811  amim-eta-no2-dfzdap4761  piraz-diphmem-no1-bphabs             4812  pyraz-25oxman2-chexo-asppha4762  deam-pentadi-eoco-aspibua            4813  bim-mepazin-4pho-psdapee4763  dmam-dimen-5pho-oxal                 4814  cl3pyme-pazi2n-napo-csdap4764  gua-24thiz-ocho-psdab                4815  fthpym-indan2-peo-psdapee4765  bhs-mepipe-oem-bsdap                 4816  am2py-n2o2n-oeto-csdap4766  nmor-pazin-5amo-bphabs               4817  mam2py-eta-meto-bhsdap4767  bzl-ams2-napo-mezphe                 4818  2pmhs-pazi2n-mmen-dfzdap4768  me2py-pentadi-mmen-zorn              4819  cl3pyme-dimephmem-oem-bsdap4769  nmhs-m24oxman2-4pho-bsdap            4820  prhs-tridi-no1-dfzdap4770  impy-24thiz-imo-asppha               4821  dmthpym-tridi-5amo-zdab4771  hythpym-pymea-cno-bhsdap             4822  hythpym-eta-no1-dfzdap4772  bhs-25oxman2-mecpo-betadcph          4823  morhs-ams2-mes-bsdap4773  cl3pyme-dimen-oeto-aspbzla           4824  thpym-mepipe-no2-bnsdap4774  amim-dipch-no2-dfzdap                4825  bz-amn2-napo-zdab4775  2py-m25thizman2-cpro-psdab           4826  hythpym-pazi2n-meo-psdab4776  me2py-diphmep-meo-dfzdap             4827  dhim-mepazin-eoco-bphabs4777  thpym-amn2-ocho-bhsdap               4828  ec-mepipen2-imo-zdabs4778  bhs-mepipe-ocho-bsdap                4829  z-pipmes-napo-asppha4779  dpam-pnymea-ocho-bhsdab              4830  mam2py-m24thizman2-emo-zdabs4780  imhs-m24thizman2-ocho-zorn           4831  2py-amn2-5pho-zdap4781  thpym-n24thiman-oem-zdabs            4832  bz-amn2-5amo-csdap4782  thpym-pipmea-pheo-csdap              4833  thpym-mepipe-meo-zdab4783  prhs-m25thizman2-no2-oxal            4834  mam2py-m24thizman2-fo-asppha4835  bhs-mepipe-mes-psdap                4885  mepip-tridi-mommo-bhsdab4836  nim-edian2-men-bhsdab               4886  amim-dimephmep-men-glyzdap4837  piraz-n24thiman-men-betapy          4887  phhs-propa2s-meo-zdabs4838  piraz-mepazin-no2-zdab              4888  bim-amn2-meo-zdab4839  hythpym-m24thizman2-emo-zdap        4889  2py-3pazin-daco-tsdap4840  phhs-diphmem-5pho-betapy            4890  imhs-pentadi-fo-aspbzla4841  mam2py-3pazin-no1-psdap             4891  hythpym-din-mes-tsdap4842  bim-dis-napo-bphabs                 4892  piraz-diphmep-napo-zdab4843  me2py-diphmem-imo-aspbzla           4893  ec-amo2-oeto-zdap4844  emnim-ams2-napo-bhsdab              4894  imhs-eta-no1-bsdap4845  deam-pipa-ocho-asppha               4895  imhs-n24thiman-oem-bphabs4846  morhs-props-emo-aspbzla             4896  mam2py-eta2s-fo-asppha4847  pyr-diphmep-paco-psdapee            4897  dhim-diphmem-meo-betainyl4848  bim-pentadi-mes-tsdap               4898  mepip-dimen-men-psdab4849  bim-mepipe-mes-bnsdap               4899  amthiaz-tridi-emo-glyzdap4850  bimhs-trias-meo-bsdap               4900  pyrhs-mepazin-5amo-csdap4851  bhs-mepipe-no1-betapy               4901  bimhs-25thiman2-ocho-zdabs4852  ec-pipa-oem-aspbzla                 4902  bimhs-trias-pyo-aspibua4853  2py-dimephmep-peo-zdap              4903  hythpym-ams2-mommo-aval4854  bim-mepazin-5pho-aspbzla            4904  impy-pyma2-5amo-glubzla4855  hythpym-am3-sem-nbeta34-            4905  npip-25oxman2-no2-bphabs
  dimeoph                             4906  mam2py-dimephmem-emo-bsdap4856  thpym-pyma2-men-ppsdap              4907  2pmhs-din-5amo-betainyl4857  imhs-pazin-5pho-psdab               4908  bimhs-butn-chexo-psdab4858  2py-eta-no2-betapy                  4909  impy-indan2-mes-bhsdab4859  dhim-pazin-hso-psdab                4910  ppy-dimephmem-fo-csdap4860  piraz-dimen-men-psdab               4911  bz-pazin-oem-bhsdab4861  2pmhs-tetradi-napo-zdab             4912  2py-diphmep-napo-zdap4862  pippy-pipa-chexo-aspaba             4913  pyr-25thiz-emo-bphabs4863  bhs-am3diaz-chexo-aspaba            4914  bhs-pyma2-mmen-ppsdap4864  bhs-dis-baeo-mezphe                 4915  impy-pipmea-men-aval4865  pippy-25thiman2-oem-dfzdap          4916  dhim-m24thizman2-daco-bnsdap4866  menim-edian2-cnmo-betadcph          4917 tolhs-trias-4amo-bphabs4867  2pmhs-m25thiz-no1-psdab             4918  pippy-dis-no1-dfzdap4868  thpym-amn2-5pho-zdab                4919  dhim-mepipen2-mes-aspbzla4869  pippy-m24thizman2-eoco-             4920  pyrhs-25oxman2-5amo-zlys
  betadcph                            4921  nmhs-diphmem-fo-psdab4870  phpip-ams2-oem-psdap                4922  prhs-mepazin-4amo-bhsdab4871  amim-trias-no1-zdab                 4923  am2py-m24thizman2-no1-dfzdap4872  morhs-tetradi-no2-bphabs            4924  bhs-pazin-no2-bsdap4873  mepip-mepazin-chexo-betapy          4925  nmhs-24thiz-fo-aspibua4874  emnim-pymea-5pho-dfzdap             4926  pippy-25oxman2-5pho-ibsdap4875  me2py-24thiman2-5amo-dfzdap         4927  dhim-trias-imo-asppha4876  hythpym-amo2-5amo-zdab              4928  hythpym-m25thiz-aco-bhsdap4877  impy-mepipen2-no1-betapy            4929  piraz-pipmea-meto-bhsdab4878  dhim-pipmea-men-zlys                4930  bhs-amo2-chexo-oxal4879  phhs-m25thiz-no1-zdabs              4931  bhs-edian2-meo-betapy4880  nim-pipa-no1-aspbzla                4932  imhs-trias-napo-zdab4881  impy-pazin-emo-zorn                 4933  bhs-mepipe-emo-zorn4882  hythpym-dimephmep-meo-zdabs         4934  nmor-eta-no1-psdap4883  pippy-pipa-cpeo-bsdap               4935  impy-thizo-fo-bhsdab4884  nmor-pentas-napo-aspibua            4936  thpym-pipa-meo-glyzdap4937  2pmhs-dimen-fo-zdabs                 4988  am2py-thizn-5amo-csdap4938  am2py-pipa-5amo-betainyl             4989  bim-eta-ocho-betapy4939  imhs-pazin-mes-zdab                  4990  nim-amn2-meteto-betadcph4940  amim-25thiz-mmen-asppha              4991  bhs-eta-ocho-bsdap4941  bim-diphmem-cpeo-betadcph            4992  me2py-am2-sem-nbetapy4942  thpym-mepipe-5pho-betapy             4993  piraz-ams2-no2-asppha4943  chhs-mepipe2-oem-nzdab               4994  am-25oxman2-eoco-zdab4944  nmor-n2o2n-imo-glubzla               4995  nmhs-pazi2n-5amo-bsdap4945  bz-amn2-meo-dfzdap                   4996  bim-indan2-emo-csdap4946  pippy-din-5pho-bnsdap                4997  imhs-dimen-peo-psdab4947  amthiaz-m25thizman2-                 4998  4pmhs-25oxman2-paco-glyzdap
  peo-bnsdap                           4999  dmam-mea-imo-zorn4948  dhim-m25thiz-mmen-csdap              5000  emnim-m25thiz-pro-ppsdap4949  2py-thizn-5amo-bphabs                5001  hythpym-amn3-oem-glyzdap4950  bim-24thizman2-ocho-psdapee          5002  dpam-pymea-emo-zdabs4951  am4py-ams2-cpeo-asppha               5003  me2py-tetradi-peo-bhsdab4952  prhs-mepazin-eoco-aspbzla            5004  nmhs-am3-oem-nbetabnaphth4953  hythpym-tridi-oem-bphabs             5005  thpym-mepipe-no1-psdap4954  am4py-25oxman2-hso-osdap             5006  4pmhs-pyma2-oem-aspibua4955  me2py-propa2s-mes-aspbzla            5007  impy-pnymea-hso-dfzdap4956  2py-edian2-no1-asppha                5008  pippy-m25thiz-chexo-psdap4957  dpam-2pazin-5amo-zdabs               5009  imhs-eta-meo-zdap4958  piraz-edia2-sem-npsdap               5010  pyr-hexadi-men-bsdap4959  thpym-ams2-eoco-betadcph             5011  2py-ams2-meo-glyzdap4960  bhs-25thiman2-emo-zdapee             5012  deam-pymea-daco-bhsdab4961  mam2py-n24thiman-pyo-bnsdap          5013  mam2py-diphmep-mes-zorn4962  emnim-pipa-ocho-asppha               5014  pippy-mepipe-mommo-bsdap4963  dhim-amn2-cpro-ppsdap                5015  bim-tridi-5pho-aspbzla4964  imhs-pazin-no2-zdab                  5016  bimhs-25oxman2-oem-bhsdab4965  dhim-m24thiz-napo-aspbzla            5017  me2py-diphmep-no1-csdap4966  pippy-din-cpro-psdab                 5018  2py-tetradi-mes-betapy4967  bim-mepipe-mes-betapy                5019  pyraz-eta-5pho-zdap4968  thpym-pymea-no2-aspbzla              5020  bim-pymea-mes-zdabs4969  piraz-amo2-5amo-bnsdap               5021  2py-pazin-no1-betapy4970  prhs-m25thiz-daco-bnsdap             5022  bim-pazin-meo-psdab4971  me2py-amo2-fo-bhsdab                 5023  2py-amn3-mecpo-zdap4972  amthiaz-hexas-5pho-aspibua           5024  2py-pnymea-ocho-psdap4973  gua-pnymea-eoco-aspbzla              5025  dhim-24thiman-cpro-betainyl4974  hythpym-trias-no2-psdap              5026  bim-pipa-5pho-mezphe4975  impy-25oxman2-napo-betadcph          5027  pippy-dimephmem-5pho-asppha4976  piraz-mepipen2-mes-zorn              5028  bhs-edian2-eoco-bhsdap4977  dhim-mepipen2-5pho-bhsdap            5029  ec-edia2-sem-nbetabnaphth4978  amim-tetradi-fo-betadcph             5030  thpym-pazin-mes-psdab4979  am2py-pazin-oem-bphabs               5031  tolhs-dimen-5pho-betainyl4980  bhs-pipmea-no2-aspibua               5032  imhs-amn2-meo-zdap4981  thpym-tridi-meo-aspbzla              5033  piraz-3diaz-daco-mezphe4982  imhs-amn3-napo-zlys                  5034  bim-25thizman2-napo-bnsdap4983  me2py-dimephmep-no1-aspibua          5035  ec-ams2-cnmo-glyzdap4984  morhs-am2-oem-nzdap                  5036  bim-mepipe-no1-bsdap4985  phhs-trias-5amo-dfzdap               5037  2py-pazin-eoco-psdab4986  bhs-amo2-imo-bsdap                   5038  bimhs-mea2s-ocho-betadcph4987  pippy-pnymea-napo-mezphe5039  me2py-m24thizman2-eoco-               5090  moegua-24thiman-emo-mezphe
  glyzdap                               5091  am2py-edia2-sem-nzdab5040  nim-m25thiz-emo-bhsdap                5092  dpam-ams2-5amo-aspbzla5041  imhs-thizn-5pho-psdapee               5093  am2py-dimephmep-baeo-betapy5042  me2py-trias-5amo-asppha               5094  dhim-trias-meteto-bnsdap5043  2py-eta-hso-zdab                      5095  2py-amn2-mes-bhsdap5044  nim-dis-chexo-zdab                    5096  imhs-diphmem-ocho-thizzdap5045  am2py-din-imo-betainyl                5097  bhs-edian2-mes-bnsdap5046  me2py-mepipen2-eoco-psdab             5098  2py-pazin-no2-zdap5047  imhs-eta-oem-zdap                     5099  amim-eta-oeto-zdapee5048  2py-dimen-eoco-asppha                 5100  nmor-25oxman2-imo-asppha5049  mam2py-3diaz-emo-aspbzla              5101  imhs-eta-5pho-bnsdap5050  thpym-eta-meo-zdab                    5102  2py-pnymea-5pho-betadcph5051  mam2py-amo2-daco-bsdap                5103  bimhs-trias-peo-bhsdab5052  bim-thizn-meo-zdap                    5104  bhs-am2-oem-nzdap5053  am2py-hexadi-oem-bsdap                5105  amim-ams2-mes-bsdap5054  bim-pymea-cno-dfzdap                  5106  am4py-thizn-no1-betainyl5055  imhs-dis-no1-zdabs                    5107  hythpym-pymea-napo-tsdap5056  menim-din-meo-glyzdap                 5108  deam-propn-meo-csdap5057  2py-pnymea-men-asppha                 5109  am2py-mepipe-cpeo-bhsdab5058  bhs-amn2-ocho-psdap                   5110  2py-mepipe-5pho-bnsdap5059  dpam-amo2-eoco-zdap                   5111  bhs-pazin-5pho-psdab5060  impy-amn3-pro-asppha                  5112  morhs-butn-pro-betapy5061  pyr-amn3-5amo-osdap                   5113  mepip-24thiz-oeto-psdab5062  hythpym-amo2-ocho-bnsdap              5114  piraz-edian2-napo-bsdap5063  imhs-eta-meo-bhsdap                   5115  mam2py-trias-imo-zdabs5064  bimhs-mepipe-paco-bhsdap              5116  impy-hexas-napo-bnsdap5065  pippy-pyma2-oeto-betainyl             5117  imhs-dich-mes-glubzla5066  nmhs-mepipe-5amo-zdab                 5118  2py-propa2s-aco-csdap5067  chmbim-tetradi-pyo-aspbzla            5119  impy-dimephmem-5amo-bnsdap5068  im-pnymea-pyo-csdap                   5120  bim-am3diaz-men-betapy5069  emnim-ams2-emo-betapy                 5121  4pmhs-tridi-5pho-bsdap5070  bhs-dimephmem-mes-glupha              5122  mam2py-pazi2n-cpeo-glyzdap5071  hythpym-pipa-chexo-aval               5123  2py-m24oxman2-baeo-zdapee5072  piraz-mepazin-chexo-csdap             5124  dmam-ams2-imo-dfzdap5073  hythpym-eta2s-napo-glyzdap            5125  amim-mepipe-chexo-psdab5074  me2py-diphmep-fo-oxal                 5126  dmbim-pipmeo-mes-thizzdap5075  bim-25thiz-eoco-bphabs                5127  imhs-eta-imo-zdap5076  mam2py-dis-men-aspibua                5128  2py-eta-no2-bhsdap5077  am2py-eta2s-meo-dfzdap                5129  bimhs-pyma2-meo-zdabs5078  me2py-tridi-no2-aspibua               5130  2py-n2o2n-chexo-zdabs5079  bim-am3-oem-nzdab                     5131  morhs-pymea-hso-aspbzla5080  chhs-dimen-pheo-dfzdap                5132  2pmhs-indan2-5pho-zdabs5081  thpym-eta-ocho-psdap                  5133  hythpym-25oxman2-cno-psdab5082  nmhs-m24thiz-napo-psdab               5134  bim-pazin-5pho-bhsdap5083  mam2py-am3-oem-nbetapy                5135  dpam-thizn-imo-dfzdap5084  impy-pymea-mecpo-thizzdap             5136  thpym-mepipe-5pho-psdap5085  n2py-24thizman2-chexo-psdab           5137  imhs-ams2-mes-betainyl5086  bzl-pazin-mommo-oxal                  5138  gua-thizo-5pho-glyzdap5087  thpym-am3diaz-no2-bsdap               5139  prhs-dipch-men-zdap5088  prhs-24thizman2-oeto-bhsdab           5140  amim-m25thiman2-oem-betadcph5089  bhs-24thiz-pro-zdabs                  5141  me2py-m25thiman2-no1-betainyl5142  bhs-pyma2-5amo-tsdap                5192  ec-amn3-fo-betadcph5143  dhim-25oxman2-no1-betainyl          5193  2py-diphmem-baeo-csdap5144  bimhs-25oxman2-mes-glyzdap          5194  ec-eta-men-mezphe5145  dpam-24thizman2-oem-aspibua         5195  amim-24thizman2-5amo-bnsdap5146  imhs-dipch-5pho-psdap               5196  2py-edia2-sem-nzdab5147  dmthpym-pipmea-eoco-zdabs           5197  pyraz-25thiman2-mes-dfzdap5148  nmor-mea-imo-betaet                 5198  bhs-eta-eoco-bnsdap5149  z-ams2-oem-zdab                     5199  thpym-tridi-no2-aspibua5150  me2py-edian2-no1-zdab               5200  ec-dich-nmo-bnsdap5151  ppy-propn-pyo-zdabs                 5201  pyr-pipmea-4pho-tsdap5152  nmhs-tridi-5pho-aspibua             5202  dhim-24thiman-imo-psdab5153  dmam-edian2-emo-dfzdap              5203  amim-thizn-mes-dfzdap5154  pippy-m25thiz-chexo-bhsdab          5204  chhs-edian2-5pho-csdap5155  impy-diphmep-no1-bphabs             5205  thpym-amn2-oem-psdab5156  2py-n2nme2n-5amo-betainyl           5206   fthpym-pipmea-no1-dfzdap5157  imhs-mepazin-meo-asppha             5207  nim-mepipen2-no1-betadcph5158  pyr-mepipe-imo-glyzdap              5208  piraz-edian2-no2-ibsdap5159  hythpym-dimephmep-napo-             5209  am2py-amn2-men-betainyl
  glubzla                             5210  emnim-m25thiz-napo-dfzdap5160  phpip-eta-napo-mezphe               5211  amim-edia2-oem-nzdab5161  dmam-pazin-men-betainyl             5212  bhs-mepipe-eoco-betapy5162  bhs-eta-5amo-zdabs                  5213  dmthpym-pazin-no2-zdabs5163  2py-edian2-oem-bsdap                5214  piraz-edian2-napo-bsdap5164  chhs-amo2-4pho-bnsdap               5215  me2py-edia2-sem-nbetameph5165  2py-tridi-mecpo-asppha              5216  am2py-din-eoco-zdab5166  n2py-diphmep-no2-betainyl           5217  imhs-amn3-meteto-aspbzla5167  me2py-eta-paco-asppha               5218  ec-m24thizman2-oem-bhsdap5168  bhs-amo2-aco-psdap                  5219  bim-dipch-mecpo-betainyl5169  2py-mepipe-ocho-bnsdap              5220  pippy-dimephmem-fo-aspbzla5170  amim-pyma2-fo-ibsdap                5221   fthpym-amo2-chexo-asppha5171  gua-mepazin-napo-betainyl           5222  fthpym-pymea-meo-psdab5172  bhs-am2-sem-nbetapy                 5223  pyraz-ams2-emo-psdap5173  gua-m24thizman2-5pho-dfzdap         5224  bhs-eta-meo-psdab5174  edothpym-m25thizman2-mes-           5225  bhs-edian2-mes-zdap
  aspbzla                             5226  nim-diphmem-men-dfzdap5175  amthiaz-thizn-fo-psdab              5227  amim-pipmea-daco-thizzdap5176  mam2py-pazin-emo-ibsdap             5228  2py-25oxman2-meo-csdap5177  pippy-25thiz-oem-zdapee             5229  dpam-diphmep-napo-bhsdap5178  bimhs-pnymea-meo-zdap               5230  mam2py-dimen-men-aval5179  mam2py-props-meo-glubzla            5231  bimhs-m24thizman2-4pho-psdab5180  dhim-dimen-mecpo-aspibua            5232  dhim-am3-sem-nzdap5181  nmor-eta-5amo-glyzdap               5233  impy-mepipe-meo-betadcph5182  impy-pnymea-imo-bnsdap              5234  bz-mepazin-emo-bhsdap5183  pyrhs-24thiz-emo-zorn               5235  fthpym-tridi-5amo-bsdap5184  dmbim-din-chexo-psdab               5236  am2py-pipa-meto-glyzdap5185  amim-tetradi-napo-zdabs             5237  bhs-mepipe-meo-bsdap5186  am2py-amn3-ocho-mezphe              5238  me2py-propa2s-fo-bnsdap5187  dhim-pipmea-napo-betainyl           5239  cl3pyme-trias-mecpo-glyzdap5188  thpym-m24thiz-napo-bhsdap           5240  phhs-mea-no2-betainyl5189  tolhs-mepazin-5pho-betainyl         5241  hythpym-tetradi-no1-mezphe5190  mam2py-dimen-pro-ibsdap             5242  bhs-eta-eoco-betapy5191  mam2py-pazin-mes-dfzdap             5243  phpip-mepazin-ocho-psdap5244  piraz-trias-eoco-zdap                5295  ec-thizn-daco-betaet5245  bim-dimephmep-oem-zdabs              5296  bim-pnymea-5amo-asppha5246  am2py-m24thizman2-men-asppha         5297  z-tetradi-napo-betapy5247  bhs-pazin-mes-psdab                  5298  amim-diphmem-eoco-asppha5248  2py-trias-chexo-zdabs                5299  pippy-pnymea-fo-glyzdap5249  bimhs-mepipen2-mes-zdabs             5300  dhim-ams2-mes-dfzdap5250  pyrhs-25oxman2-meo-aspaba            5301  mam2py-pnymea-napo-osdap5251  gua-edia2-sem-nzdap                  5302  me2py-dis-imo-glupha5252  2py-mepipen2-cpro-psdap              5303  dhim-ams2-fo-bhsdap5153  me2py-mepazin-5amo-zdab              5304  piraz-ams2-men-bnsdap5254  am2py-pazin-5pho-betainyl            5305  chhs-pnymea-chexo-mezphe5255  amim-dich-imo-psdab                  5306  n2py-m24thizman2-5amo-aspbzla5156  piraz-dipch-cpeo-mezphe              5307  bimhs-thizo-emo-betainyl5257  hythpym-24thizman2-no2-zdab          5308  gua-24thizman2-meo-zdabs5258  deam-24thiman2-no2-asppha            5309  hythpym-24oxman2-oem-psdab5259  bhs-25oxman2-ocho-asppha             5310  bim-mepipe2-oem-nbeta34-5260  amim-amo2-5pho-thizzdap                    dimeoph5261  bhs-amo2-imo-betadcph                5311  bim-pazin-no2-bhsdap5262  dmthpym-mea-5amo-mezphe              5312  4pmhs-n24thiman-oem-csdap5263  dhim-m25thizman2-5amo-               5313  dhim-thizs-eoco-bphabs
  betainyl                             5314  phhs-pazin-meo-zdabs5264  dmthpym-propn-eoco-dfzdap            5315  mam2py-25oxman2-meo-bhsdap5265  pyr-24thiz-fo-aspbzla                5316  am2py-mepipe2-sem-npsdap5266  impy-diphmep-mes-psdap               5317  impy-m24thiz-ocho-asppha5267  pyrhs-pazi2n-imo-betadcph            5318  2py-24thiman-oeto-psdap5268  mam2py-trias-meo-bhsdap              5319  hythpym-pyma2-5amo-zlys5269  piraz-tetradi-ocho-psdab             5320  hythpym-thizn-napo-aspbzla5270  fthpym-pipmeo-meo-mezphe             5321  amim-n2nme2n-ocho-psdapee5271  tolhs-edia2-oem-npsdap               5312  mam2py-thizn-mommo-dfzdap5272  2py-mepipe-no1-betapy                5323  bim-dimephmem-5amo-bhsdap5273  pyraz-25oxman2-oem-aspbzla           5324  bim-pipmea-no2-dfzdap5274  bhs-pipa-hso-csdap                   5325  ppy-dimephmep-emo-dfzdap5275  mam2py-pnymea-oem-psdab              5326  am2py-amo2-oem-betadcph5276  im-eta-daco-zorn                     5327  dmthpym-24thiz-mes-zdap5277  cl3pyme-diphmem-ocho-bsdap           5328  2py-amn2-napo-betapy5278  fthpym-dimen-5amo-bsdap              5329  impy-diphmep-pro-bsdap5279  impy-pipmeo-daco-zdap                5330  ibhs-mepipen2-5pho-bhsdap5280  dhim-edian2-5pho-betadcph            5331  2py-m24oxman2-5amo-aspaba5281  bimhs-dimen-fo-bphabs                5332  bhs-amn2-meo-bhsdap5282  dhim-pnymea-emo-betainyl             5333  moegua-m25thiz-pro-glyzdap5283  thpym-m25thiz-mommo-csdap            5334  thpym-ams2-meto-betaet5284  hythpym-25oxman2-imo-zdab            5335  me2py-pipmea-imo-bphabs5285  pyr-am2-sem-nzdab                    5336  amim-pazin-5pho-osdap5286  phhs-m25thiz-5amo-bhsdab             5337  pyraz-pymea-pheo-betaet5287  thpym-pazin-mes-zdap                 5338  dmam-pyma2-cnmo-zorn5288  dhim-props-napo-betainyl             5339  bhs-edian2-eoco-psdap5289  cl3pyme-edia2-sem-nzdab              5340  phpip-pipa-ocho-asppha5290  2py-ams2-imo-bhsdap                  5341  am2py-propa2s-oem-zdap5291  bim-edian2-eoco-zdap                 5342  emnim-am2-oem-nzdap5292  piraz-mea2s-ocho-zdab                5343  gua-trias-peo-csdap5293  piraz-edian2-eoco-glyzdap            5344  imhs-m25thiman2-napo-betainyl5294  bimhs-diphmep-5pho-csdap             5345  bhs-am3-oem-nbeta34dimeoph5346  dmbim-25thiz-chexo-zdap           5398  mepip-m24thizman2-fo-mezphe5347  ppy-m24thizman2-5amo-zdap         5399  me2py-mepipe-5amo-glyzdap5348  moegua-m24thiz-5amo-psdap         5400  bzl-mepipen2-imo-zdabs5349  impy-dimephmem-napo-mezphe        5401  bim-eta-mes-bhsdap5350  me2py-24thiz-meo-oxal             5402  me2py-amo3-emo-betainyl5351  thpym-amn3-5amo-aspbzla           5403  gua-tetradi-pro-zdab5352  menim-mepipe-pro-aspibua          5404  n2py-pipa-chexo-betainyl5353  2py-tetradi-5amo-bnsdap           5405  edothpym-24thizman2-imo-zdabs5354  edothpym-am3-oem-nbetabnaphth     5406  dhim-pipa-no2-tsdap5355  bimhs-propn-napo-glyzdap          5407  nmor-ams2-ocho-bhsdab5356  imhs-am2-sem-nbetabnaphth         5408  amthiaz-amn2-no1-zdabs5357  piraz-mepipe-oem-betadcph         5409  2py-ams2-emo-zdabs5358  piraz-edian2-chexo-betainyl       5410  2pmhs-indan2-eoco-mezphe5359  bzl-24thiz-eoco-asppha            5411  pippy-am3diaz-oem-asppha5360  bim-trias-meteto-oxal             5412  amim-pazin-men-bhsdab5361  imhs-edian2-no1-betapy            5413  hythpym-mepipe-ocho-betapy5362  amthiaz-tridi-mes-glyzdap         5414  amim-diphmem-cpro-aspbzla5363  im-24thiman2-ocho-asppha          5415  pyraz-eta2s-ocho-glyzdap5364  piraz-24thiz-5amo-bsdap           5416  bim-pazin-5pho-aval5365  amim-pipmea-4pho-csdap            5417  amim-mepazin-mes-psdap5366  me2py-24oxman2-hso-ibsdap         5418  dhim-amn3-emo-zdab5367  bhs-pazin-ocho-bhsdap             5419  amthiaz-m24thizman2-5368  bhs-amn2-5pho-zdap                      5pho-psdab5369  2pmhs-tridi-cno-bphabs            5420  bz-3diaz-imo-zdab5370  bz-25thiman2-oeto-aspibua         5421  bimhs-amo2-emo-asppha5371  ppy-diphmep-cpeo-betainyl         5422  bim-tetradi-fo-betainyl5372  bimhs-pyma2-hso-psdap             5423  2py-amn2-no1-betapy5373  thpym-pazin-5pho-bnsdap           5424  amim-amo2-oem-psdap5374  me2py-edia2-oem-nbetapy           5425  2py-n2o2n-peo-betadcph5375  bimhs-diaz-oem-glyzdap            5426  bhs-pazin-oem-zdap5376  nmor-pymea-fo-psdap               5427  phhs-m24thizman2-5pho-zdab5377  piraz-m24thiz-eoco-betainyl       5428  nim-m24oxman2-5amo-bhsdap5378  moegua-pazin-eoco-dfzdap          5429  thpym-eta-ocho-bnsdap5379  imhs-edian2-mes-bnsdap            5430  imhs-tetradi-meo-csdap5380  am2py-din-emo-thizzdap            5431  2py-pazin-oem-bnsdap5381  me2py-pentas-oem-bnsdap           5432  hythpym-ams2-napo-betapy5382  dhim-dimephmem-cnmo-zdapee        5433  ec-din-imo-aspbzla5383  bhs-pymea-no2-glubzla             5434  thpym-din-nmo-bsdap5384  bhs-m25thiz-mes-psdab             5435  n2py-tetradi-emo-tsdap5385  2py-mepipe-ocho-betapy            5436  bimhs-n24thiman-4pho-thizzdap5386  bhs-edian2-napo-psdab             5437  dhim-diphmep-mes-dfzdap5387  thpym-edian2-oem-zdap             5438  bhs-mepipe-no1-zdap5388  bim-edian2-oem-psdap              5439  bhs-mepipe-no2-psdab5389  pippy-24thizman2-5pho-mezphe      5440  imhs-amn2-no1-bnsdap5390  am-dimen-mes-psdab                5441  impy-pnymea-ocho-psdab5391  am2py-props-men-psdab             5442  dhim-din-ocho-betainyl5392  mam2py-pipa-mes-betadcph          5443  chmhs-m24thizman2-mommo-osdap5393  am2py-pipmea-napo-glupha          5444  bimhs-pazin-mes-betaet5394  fthpym-mepipe-nmo-bnsdap          5445  2py-m25oxman2-eoco-betapy5395  me2py-pipmea-pro-dfzdap           5446  me2py-m24oxman2-oem-bsdap5396  mam2py-3diaz-4amo-ibsdap          5447  bhs-dimephmep-chexo-bphabs5397  piraz-3pazin-oem-bsdap            5448  emnim-pipa-ocho-csdap5449  dhim-thizn-no1-bhsdab               5500  moegua-tridi-5amo-psdapee5450  dhim-diaz-5pho-dfzdap               5501  hythpym-m24thiman2-cpro-csdap5451  bimhs-m24thiman2-emo-bhsdap         5502  am4py-24thiman2-nmo-csdap5452  2py-amo2-napo-dfzdap                5503  me2py-eta-cnmo-glyzdap5453  4pmhs-thizo-cno-csdap               5504  am4py-tetradi-eoco-betadcph5454  dhim-diphmem-oem-zdab               5505  piraz-eta-peo-tsdap5455  bim-ams2-5amo-psdap                 5506  bim-eta2s-men-mezphe5456  dhim-thizn-no1-aspbzla              5507  phhs-dimephmep-oem-mezphe5457  dhim-25thiz-fo-bhsdap               5508  emnim-pipmes-eoco-ibsdap5458  imhs-mepipe-5pho-bsdap              5509  bim-mepipe-no1-betapy5459  amim-trias-imo-dfzdap               5510  2pmhs-24thiz-napo-bnsdap5460  dmbim-dimephmep-napo-betapy         5511  pyrhs-amn3-mes-bhsdab5461  2py-24thiman2-imo-betainyl          5512  dhim-edia2-sem-nbetabnaphth5462  imhs-pyma2-oem-betapy               5513  piraz-diphmem-men-zdab5463  am2py-dio-eoco-bnsdap               5514  phpip-pyma2-napo-bnsdap5464  fthpym-25oxman2-oeto-bnsdap         5515  bim-mepipe-eoco-betapy5465  me-ams2-cno-glyzdap                 5516  im-pipa-5pho-aspbzla5466  impy-am3-sem-npsdap                 5517  me2py-eta-5amo-bsdap5467  me2py-eta-ocho-dfzdap               5518  bim-eta-eoco-zdap5468  bhs-thizn-pheo-mezphe               5519  ibhs-pipa-cpeo-glyzdap5469  mam2py-24thiz-imo-betainyl          5520  cl3pyme-eta-mes-zdab5470  dhim-amo2-fo-zdap                   5521  2py-eta-ocho-zdap5471  emnim-m25thiz-napo-zdap             5522  dhim-eta-peo-dfzdap5472  thpym-m24thizman2-mes-zdap          5523  dhim-24thiz-mes-betaet5473  dhim-pyma2-napo-bhsdap              5524  thpym-pnymea-meo-zdap5474  thpym-m24thizman2-napo-tsdap        5525  fthpym-dis-chexo-zorn5475  me2py-25thizman2-eoco-              5526  mam2py-dimephmem-cnmo-csdap
  betadcph                            5527  bimhs-24thizman2-pro-glubzla5476  thpym-edian2-5pho-ppsdap            5528  bim-amn2-oem-zdab5477  2py-dio-mommo-glyzdap               5529  morhs-ams2-5amo-csdap5478  bimhs-butn-meo-zdabs                5530  mam2py-amo2-fo-zdab5479  dhim-24thiz-cnmo-ibsdap             5531  thpym-mepipe-oem-psdap5480  pippy-amo2-pyo-bhsdap               5532  impy-ms-chexo-glyzdap5481  bim-dimen-ocho-betaet               5533  tolhs-pentas-mes-glyzdap5482  bim-m25oxman2-imo-zdabs             5534  bim-eta-no2-zdab5483  imhs-dimen-paco-zdapee              5535  imhs-mepipe-ocho-psdab5484  2py-eta-mes-bsdap                   5536  me2py-thizn-mes-aspibua5485  2py-pentas-men-dfzdap               5537  bhs-m25oxman2-5amo-betadcph5486  me2py-amn2-meteto-aspbzla           5538  mepip-din-4amo-glyzdap5487  me-mepazin-emo-aspibua              5539  am2py-mepipe-baeo-bhsdab5488  bim-dimephmep-emo-dfzdap            5540  moegua-m24thiz-mes-csdap5489  bim-diphmep-emo-zdabs               5541  bhs-mepipe-ocho-psdap5490  me2py-n2nme2n-fo-betapy             5542  bhs-eta-5pho-bsdap5491  phhs-pipmeo-men-bhsdab              5543  dpam-m24thizman2-cpeo-zdab5492  bimhs-am3diaz-no1-betainyl          5544  bhs-eta-chexo-bhsdap5493  bhs-edian2-oem-zdab                 5545  2py-propn-imo-bphabs5494  thpym-tetradi-no2-csdap             5546  dhim-amn2-4pho-betapy5495  thpym-m25thiz-emo-bnsdap            5547  me-tetradi-oem-dfzdap5496  am2py-amn3-eoco-bhsdap              5548  bim-dis-ocho-bhsdap5497  cl3pyme-amo2-daco-psdap             5549  bim-amn2-ocho-zdab5498  z-dipch-men-glyzdap                 5550  thpym-edian2-mes-bsdap5499  2py-mepipe-no2-bnsdap               5551  mam2py-edian2-fo-zdap5552  2py-pyma2-no2-bhsdab               5604  piraz-pipa-meo-mezphe5553  gua-diphmem-emo-osdap              5605  mepip-pipmea-chexo-glyzdap5554  piraz-25oxman2-no1-mezphe          5606  hythpym-m25thiz-paco-bnsdap5555  thpym-edian2-5pho-bhsdap           5607  piraz-m24thizman2-mes-betaet5556  bim-edian2-meo-bhsdap              5608  bz-edian2-men-aspbzla5557  thpym-amn2-5pho-bhsdap             5609  bim-edia2-oem-nbetabnaphth5558  me2py-mepipen2-imo-zdap            5610  bhs-m25thiz-napo-bhsdap5559  imhs-dimephmem-oem-bhsdap          5611  bimhs-25oxman2-mecpo-mezphe5560  phpip-m25oxman2-no1-bhsdab         5612  deam-24thiz-pheo-aspbzla5561  impy-edian2-no2-psdab              5613  bimhs-edian2-paco-ppsdap5562  bimhs-trias-ocho-aval              5614  mam2py-ams2-fo-bnsdap5563  imhs-edian2-mmen-mezphe            5615  me2py-pipa-no2-zorn5564  me2py-m24oxman2-5pho-mezphe        5616  bim-mepipe2-sem-nbeta34-5565  amim-dimen-napo-zdap                     dimeoph5566  piraz-pnymea-cpro-aspbzla          5617  bhs-amn2-ocho-zdab5567  am2py-m25thiz-5amo-betainyl        5618  4pmhs-trias-napo-zdab5568  deam-m25thiz-napo-asppha           5619  emnim-m25oxman2-men-bhsdap5569  piraz-diphmem-5pho-ibsdap          5620  bim-mepipe-ocho-bhsdap5570  impy-dimephmem-daco-thizzdap       5621  impy-25oxman2-oem-zdap5571  impy-m24thizman2-no2-bnsdap        5622  thpym-pnymea-no1-zdabs5572  bhs-eta-ocho-bnsdap                5623  am2py-mepazin-oem-bphabs5573  pyraz-am2-sem-nbetapy              5624  thpym-amn2-eoco-bnsdap5574  amim-24thizman2-no1-bsdap          5625  me2py-24thizman2-ocho-zdabs5575  2py-amn3-5pho-bnsdap               5626  emnim-m25thiz-ocho-asppha5576  dmthpym-butn-pyo-dfzdap            5627  gua-tetradi-aco-zdab5577  bim-amn2-no2-bnsdap                5628  nim-m25thizman2-peo-zdab5578  moegua-indan2-chexo-betapy         5629  bimhs-24thiz-no2-betapy5579  pippy-m24oxman2-meo-csdap          5630  phhs-pnymea-4pho-aspbzla5580  bimhs-tridi-no2-betainyl           5631  hythpym-ams3-5pho-bphabs5581  pippy-edian2-no1-psdap             5632  dmam-dis-oem-bsdap5582  dpam-n2o2n-eoco-oxal               5633  bhs-edian2-meo-psdap5583  fthpym-pipa-chexo-glyzdap          5634  pyr-eta-oeto-betapy5584  am-pazin-5pho-zdabs                5635  hythpym-mepipe-men-aspibua5585  hythpym-dis-chexo-psdab            5636  dhim-pentadi-ocho-bhsdab5586  pyrhs-propn-meto-zdap              5637  mam2py-m24thizman2-eoco-psdap5587  bhs-24thiz-no1-aspibua             5638  am2py-thizn-mes-asppha5588  thpym-amn2-ocho-psdap              5639  ec-pipmes-men-bsdap5589  amim-n2o2n-oem-zdab                5640  amim-ms-mecpo-aspbzla5590  amim-mepipe-5pho-oxal              5641  edothpym-trias-men-asppha5591  dmam-m24thiz-5pho-aspaba           5642  am2py-mepipen2-no2-bphabs5592  n2py-3pazin-chexo-bsdap            5643  bimhs-tridi-imo-glyzdap5593  impy-dio-chexo-betadcph            5644  imhs-propn-no1-bhsdap5594  bim-hexas-meo-bphabs               5645  hythpym-25oxman2-5pho-5595  npip-edian2-no2-glyzdap                  betadcph5596  amim-pipmea-ocho-bphabs            5646  imhs-pazin-ocho-psdab5597  ibhs-mepipe-emo-bphabs             5647  dhim-dimephmep-pheo-zdab5598  mepip-pnymea-meteto-aspibua        5648  amim-pyma2-pyo-zdap5599  piraz-am3-sem-nbeta34dimeoph       5649  imhs-pazin-ocho-zdap5600  me2py-dipch-5amo-csdap             5650  me2py-24thiz-cno-bsdap5601  morhs-3pazin-chexo-zlys            5651  bimhs-edian2-mes-csdap5602  imhs-dimen-fo-betapy               5652  impy-pnymea-ocho-zdap5603  ibhs-24thiz-chexo-bhsdab           5653  mam2py-pymea-oem-bsdap5654  n2py-dipch-aco-aspbzla                5705  4pmhs-pipa-napo-betadcph5655  mam2py-m24thizman2-eoco-              5706  mam2py-eta-fo-psdap
  mezphe                                5707  impy-mepipe-fo-asppha5656  npip-butn-oem-betaet                  5708  bimhs-m24thizman2-mes-psdab5657  amim-ms-eoco-zdabs                    5709  bim-pazin-chexo-mezphe5658  bim-mepipe-ocho-zdap                  5710  bimhs-pnymea-napo-bhsdap5659  am2py-mepipe-5pho-zdapee              5711  2py-eta-meo-bsdap5660  imhs-eta-ocho-betapy                  5712  amim-amn3-chexo-aspbzla5661  2py-eta-5pho-zdap                     5713  phhs-mepipe-mecpo-zlys5662  dhim-edia2-oem-nbetameph              5714  amim-mepipe2-sem-nbetabnaphth5663  pyraz-amo2-eoco-betaet                5715  bimhs-hexas-napo-zdap5664  pyrhs-24thiz-meteto-psdapee           5716  pifaz-dimephmep-5pho-bphabs5665  mam2py-am3diaz-fo-bhsdap              5717  am4py-dich-paco-aval5666  dhim-25oxman2-emo-zdab                5718  piraz-diaz-no1-bnsdap5667  fthpym-thizs-peo-glubzla              5719  morhs-pymea-5amo-betapy5668  bzl-amo2-imo-bsdap                    5720  ppy-pnymea-imo-psdab5669  dmthpym-pipa-chexo-betadcph           5721  thpym-edian2-men-glupha5670  bz-mepipe-napo-glyzdap                5722  nmhs-m25thiz-men-betainyl5671  thpym-amo2-chexo-zdab                 5723  edothpym-24thiman-oem-zdab5672  2py-pipmea-oem-zdapee                 5724  mam2py-25thiman2-5amo-zdapee5673  pippy-amn2-chexo-zdab                 5725  2py-hexas-mmen-tsdap5674  bim-amn2-5pho-psdap                   5726  bimhs-din-mes-betapy5675  bzl-mepipen2-5pho-csdap               5727  pippy-dio-emo-dfzdap5676  me-m24thiz-meo-aspbzla                5728  dhim-thizn-eoco-glyzdap5677  pippy-n2nme2n-daco-aspbzla            5729  npip-edian2-hso-bphabs5678  menim-24thiz-napo-mezphe              5730  nmhs-25oxman2-cno-asppha5679  mam2py-mepipe-fo-glupha               5731  bimhs-thizn-5pho-psdab5680  bim-24thizman2-cno-mezphe             5732  dmbim-edian2-oem-bnsdap5681  thpym-am3diaz-imo-csdap               5733  pippy-24thizman2-napo-betaet5682  hythpym-tridi-men-mezphe              5734  me2py-din-men-bsdap5683  thpym-mepazin-emo-psdab               5735  bhs-pazin-ocho-betapy5684  am2py-n24thiman-napo-glyzdap          5736  4pmhs-din-baeo-betainyl5685  bimhs-edian2-no2-mezphe               5737  amthiaz-mepazin-no2-bnsdap5686  amim-dimephmem-no1-betadcph           5738  npip-pipmes-no2-osdap5687  2py-thizn-ocho-osdap                  5739  2py-pipa-imo-aspibua5688  impy-dis-mes-zdapee                   5740  phpip-mepazin-no2-mezphe5689  2py-edian2-mes-psdab                  5741  piraz-pipa-5amo-betapy5690  piraz-mepipe-meo-asppha               5742  imhs-edian2-mes-psdab5691  mam2py-edian2-meo-zdap                5743  bim-pymea-ocho-glyzdap5692  phhs-dimen-no1-csdap                  5744  amim-thizn-ocho-bhsdap5693  dhim-mepipen2-chexo-bsdap             5745  bimhs-dimephmep-chexo-aspibua5694  dmbim-pipa-no2-tsdap                  5746  dmbim-hexadi-5pho-betadcph5695  2py-edian2-meo-betapy                 5747  bhs-mepazin-paco-bsdap5696  thpym-3diaz-5pho-zorn                 5748  imhs-dimephmem-aco-asppha5697  emnim-amn2-4pho-mezphe                5749  bim-pazin-eoco-bhsdap5698  amim-am3-sem-nbeta34dimeoph           5750  4pmhs-ams2-napo-asppha5699  me2py-dio-men-glupha                  5751  dhim-am3diaz-ocho-betadcph5700  amim-diphmem-mecpo-csdap              5752  impy-m25thiz-mes-csdap5701  am-pipmea-oem-betapy                  5753  pyraz-diaz-5amo-bsdap5702  me2py-edian2-5amo-zdab                5754  bim-mepipe-ocho-zdab5703  bim-dis-oeto-psdap                    5755  imhs-eta-5pho-bsdap5704  nim-pazin-mes-zdap                    5756  amim-25oxman2-no1-ibsdap5757  amthiaz-amn3-eoco-zdab              5807  am2py-amn3-5pho-zdapee5758  thpym-mepipe-5pho-psdab             5808  gua-pyma2-emo-bphabs5759  hythpym-pazin-imo-aval              5809  imhs-din-men-betadcph5760  hythpym-dimephmem-eoco-betapy       5810  pyrhs-trias-eoco-psdap5761  bhs-hexas-ocho-aspibua              5811  am2py-pymea-ocho-bhsdap5762  dmbim-tetradi-chexo-aspbzla         5812  2pmhs-dis-nmo-zdabs5763  pyrhs-am2-sem-nzdap                 5813  tolhs-tetradi-hso-dfzdap5764  pyraz-mepipe2-sem-nbeta34-          5814  dhim-24thiz-pheo-osdap
  dimeoph                             5815  am2py-pymea-cno-zdab5765  mam2py-pipmea-imo-zdap              5816  bim-dimephmep-no2-bhsdap5766  prhs-amn3-imo-betainyl              5817  pippy-thizn-mes-zdap5767  2py-24oxman2-paco-oxal              5818  bimhs-25thizman2-fo-betapy5768  impy-24thiman2-mecpo-psdap          5819  amim-am3-sem-nbeta34dimeoph5769  mam2py-pnymea-ocho-aspibua          5820  me2py-propn-eoco-psdab5770  bzl-mepazin-fo-aspbzla              5821  npip-dimephmem-imo-betapy5771  impy-tridi-eoco-betadcph            5822  im-pnymea-mecpo-betainyl5772  im-3diaz-4amo-osdap                 5823  am2py-n2nme2n-no2-aspbzla5773  npip-diphmem-5amo-oxal              5824  prhs-dimephmem-4pho-ibsdap5774  dhim-pipmes-4amo-dfzdap             5825  am2py-thizs-ocho-bhsdap5775  imhs-25oxman2-men-csdap             5826  impy-mepipe-no1-psdap5776  bimhs-m24thizman2-ocho-             5827  bhs-amo3-mes-bsdap
  glyzdap                             5828  thpym-pymea-chexo-csdap5777  imhs-dis-no2-zdap                   5829  deam-edia2-oem-nzdap5778  am2py-24thizman2-5amo-bsdap         5830  bzl-m25thiman2-5amo-zdap5779  2py-dimephmep-meteto-bphabs         5831  2py-amn2-meo-psdap5780  piraz-trias-chexo-dfzdap            5832  hythpym-diaz-hso-bsdap5781  imhs-amn2-no1-betapy                5833  dhim-24thiz-ocho-csdap5782  tolhs-m24oxman2-emo-zdab            5834  nmor-pentadi-mecpo-zorn5783  hythpym-pyma2-5amo-dfzdap           5835  imhs-pazin-no2-psdap5784  bim-indan2-men-tsdap                5836  fthpym-dimephmep-napo-aspbzla5785  4pmhs-amn3-cno-glyzdap              5837  bim-pazin-5pho-bsdap5786  imhs-dimen-imo-osdap                5838  mam2py-pymea-napo-bsdap5787  2py-indan2-aco-mezphe               5839  piraz-pipmea-fo-psdap5788  2py-dimen-ocho-psdap                5840  imhs-m25thiz-no2-bhsdap5789  hythpym-eta2s-chexo-bsdap           5841  bimhs-m25thiz-ocho-glyzdap5790  edothpym-pazin-pyo-zdabs            5842  bhs-diphmep-emo-betapy5791  bhs-edian2-no1-zdap                 5843  tolhs-dimephmem-hso-zlys5792  pippy-pazin-mes-csdap               5844  dhim-m25oxman2-ocho-psdap5793  am2py-mepazin-mommo-betadcph        5845  pyr-pnymea-no1-asppha5794  bz-mepipe-meo-zdab                  5846  am2py-amn2-mes-bhsdab5795  bim-amn3-ocho-zorn                  5847  chhs-pipmea-fo-zdab5796  phpip-m24thizman2-mes-aspbzla       5848  imhs-edian2-no1-psdab5797  bim-tridi-no1-tsdap                 5849  chhs-dimephmem-5amo-zdabs5798  tolhs-tridi-emo-aspibua             5850  bzl-dimephmem-4pho-aspbzla5799  am2py-m25thiz-5pho-zdabs            5851  z-24thiz-4amo-bphabs5800  impy-edian2-no1-glyzdap             5852  hythpym-amn2-imo-psdapee5801  hythpym-m25thiz-men-aspbzla         5853  thpym-mepipe-oem-bhsdap5802  thpym-amn2-mes-psdap                5854  2py-25thizman2-peo-asppha5803  pyrhs-ams2-emo-dfzdap               5855  impy-pnymea-mmen-bhsdap5804  pyraz-dis-eoco-csdap                5856  am2py-thizn-napo-zdap5805  am2py-pazin-men-aspbzla             5857  am2py-amn2-ocho-betapy5806  hythpym-edian2-cpeo-bhsdab          5858  bim-din-no2-psdab5859  dhim-thizn-cpro-bhsdap              5911  am2py-2pazin-napo-ppsdap5860  mam2py-tetradi-meto-csdap           5912  bzl-pymea-men-bphabs5861  amim-mepazin-imo-csdap              5913  morhs-tetradi-pyo-csdap5862  bhs-24thiz-men-bphabs               5914  imhs-tridi-chexo-zdap5863  mepip-edian2-cpro-betapy            5915  2py-edian2-eoco-bhsdap5864  impy-dimephmep-napo-bsdap           5916  fthpym-pipa-cno-betadcph5865  dhim-25thizman2-chexo-bsdap         5917  bimhs-m24thizman2-emo-aval5866  phhs-trias-oem-mezphe               5918  dhim-pnymea-5pho-aspibua5867  impy-tridi-4amo-aval                5919  imhs-diphmem-men-psdab5868  piraz-pipa-meo-csdap                5920  mam2py-amn2-meo-bhsdap5869  bz-m25oxman2-emo-asppha             5921  imhs-pentadi-mes-psdab5870  menim-diphmep-imo-aspbzla           5922  imhs-3diaz-fo-bhsdap5871  pyraz-mepipen2-imo-betapy           5923  2py-dimephmem-no1-betapy5872  imhs-dimephmem-nmo-bphabs           5924  bim-mepipe-meo-bsdap5873  2py-25oxman2-meo-glyzdap            5925  mam2py-pipmes-no2-aspbzla5874  morhs-eta-no2-betainyl              5926  impy-am3-oem-nzdap5875  pyr-mepipen2-5amo-psdab             5927  phpip-tetras-cnmo-csdap5876  pyr-ams3-imo-asppha                 5928  dhim-amn3-5pho-psdap5877  im-thizs-napo-zdap                  5929  bim-eta-ocho-bnsdap5878  bimhs-24thizman2-nmo-zdabs          5930  bimhs-amn3-cnmo-bhsdap5879  phhs-din-5amo-betapy                5931  dhim-dis-no1-aval5880  2py-pipa-ocho-zdap                  5932  tolhs-trias-men-psdab5881  piraz-pipmea-cpeo-thizzdap          5933  bzl-dimephmep-napo-psdapee5882  dmbim-pyma2-napo-glubzla            5934  am2py-dimen-emo-bnsdap5883  amthiaz-24thizman2-emo-zdabs        5935  2py-mepazin-emo-aspbzla5884  mepip-tridi-nmo-bhsdap              5936  amim-eta2s-ocho-bhsdap5885  tolhs-mepipe-napo-betapy            5937  me-mepipen2-napo-bsdap5886  thpym-24thiman2-no1-aspbzla         5938  imhs-amo2-5amo-zdabs5887  pyr-3diaz-paco-aspbzla              5939  ibhs-mepazin-ocho-betadcph5888  amim-mepazin-men-psdapee            5940  bimhs-amo2-mommo-csdap5889  piraz-25oxman2-no2-csdap            5941  nmor-diphmep-baeo-mezphe5890  ibhs-amn3-no1-dfzdap                5942  cl3pyme-am3-oem-nbetabnaphth5891  pippy-tridi-mecpo-zdabs             5943  bimhs-am2-sem-npsdap5892  2py-25thiman2-meo-betapy            5944  amim-mepipe-5amo-betapy5893  me2py-m25thiz-fo-asppha             5945  thpym-n2nme2n-ocho-zdap5894  chhs-24thiz-imo-psdab               5946  thpym-pyma2-no2-zdab5895  bhs-mepipe-no1-bhsdap               5947  imhs-thizn-no2-aspibua5896  bz-pentas-mes-asppha                5948  n2py-edian2-aco-aspbzla5897  phpip-mepipen2-no2-asppha           5949  amim-25thiman2-oem-bhsdab5898  thpym-pipa-chexo-thizzdap           5950  amthiaz-thizs-napo-thizzdap5899  am2py-dimephmem-chexo-dfzdap        5951  2py-24thiz-meo-bnsdap5900  am2py-amn2-eoco-aspibua             5952  thpym-eta-no1-zdab5901  hythpym-diphmem-imo-glyzdap         5953  morhs-pyma2-5amo-bnsdap5902  deam-dimephmep-fo-ibsdap            5954  am2py-amn3-peo-betadcph5903  imhs-amn2-mes-zdap                  5955  pippy-25thiz-5amo-asppha5904  edothpym-tetradi-meo-zdab           5956  bimhs-mepipen2-no1-psdab5905  dmthpym-thizn-5amo-aspbzla          5957  bhs-edian2-mes-zdab5906  bhs-dimephmem-men-bsdap             5958  mam2py-trias-chexo-aspibua5907  am2py-pyma2-pro-psdab               5959  thpym-amo2-ocho-bsdap5908  imhs-n24thiman-no1-bnsdap           5960  2py-diphmem-no2-bphabs5909  2py-thizn-no1-bhsdab                5961  2py-am3diaz-napo-glyzdap5910  bim-mepipe-oem-zdab                 5962  2py-tetradi-mes-bhsdap5963  mam2py-tridi-no1-mezphe            6015  bim-din-oeto-thizzdap5964  hythpym-ams2-oem-zdap              6016  fthpym-mepipe-5pho-psdap5965  bim-edian2-eoco-bnsdap             6017  hythpym-mepazin-meto-asppha5966  nmhs-trias-ocho-ppsdap             6018  thpym-edian2-mes-betapy5967  imhs-dimen-no1-dfzdap              6019  2pmhs-dimephmem-ocho-asppha5968  npip-m24thizman2-emo-psdab         6020  amthiaz-pyma2-5pho-bsdap5969  gua-24thizman2-no1-bnsdap          6021  2py-edian2-eoco-betapy5970  bimhs-25oxman2-cpeo-psdap          6022  imhs-pazin-oem-psdap5971  bhs-amo2-ocho-aspibua              6023  pippy-ams2-meo-aspibua5972  bzl-ams2-meo-bhsdap                6024  dmthpym-25oxman2-daco-bphabs5973  dmthpym-25oxman2-no1-betapy        6025  n2py-25oxman2-5amo-aspibua5974  dhim-dimephmem-chexo-betainyl      6026  bim-am3-oem-nbeta34dimeoph5975  me2py-dimephmem-men-aval           6027  thpym-tetradi-paco-betapy5976  deam-pipa-emo-bnsdap               6028  tolhs-25oxman2-emo-aspbzla5977  bim-pipmea-chexo-asppha            6029  im-thizs-emo-aspbzla5978  bim-diphmem-oem-asppha             6030  imhs-24thiz-4pho-bhsdab5979  menim-pyma2-4pho-bphabs            6031  im-tridi-no2-dfzdap5980  pippy-pymea-no2-aspbzla            6032  tolhs-edia2-oem-nbeta34-5981  bimhs-amn2-mes-betainyl                  dimeoph5982  am2py-trias-men-betapy             6033  mepip-indan2-fo-zdap5983  mam2py-tetras-4pho-dfzdap          6034  pippy-pnymea-ocho-betainyl5984  imhs-24thizman2-napo-bsdap         6035  dhim-diphmep-imo-aspaba5985  tolhs-pipa-no1-zdabs               6036  piraz-3pazin-cnmo-psdap5986  cl3pyme-tridi-mes-asppha           6037  bhs-thizo-cno-zorn5987  cl3pyme-pipmea-men-glyzdap         6038  bhs-mepipe-no2-zdap5988  piraz-mepipe-nmo-bhsdab            6039  bhs-tridi-ocho-zdabs5989  imhs-eta-ocho-psdab                6040  imhs-amn3-aco-bnsdap5990  bimhs-propn-5pho-betapy            6041  thpym-24thiz-ocho-csdap5991  dhim-pnymea-emo-glyzdap            6042  mam2py-trias-chexo-zdab5992  nmhs-pipa-no1-thizzdap             6043  amim-pazin-5pho-bhsdap5993  imhs-amn2-oem-zdab                 6044  bim-tetradi-imo-glubzla5994  tolhs-edia2-sem-npsdap             6045  2py-eta-no1-bhsdap5995  amim-mepipe-cno-osdap              6046  dmthpym-pnymea-men-bhsdap5996  pippy-edian2-imo-asppha            6047  dhim-am2-sem-nbetapy5997  me2py-amn3-5pho-zdabs              6048  2py-eta-eoco-bsdap5998  gua-pipmea-fo-zdap                 6049  dmbim-pymea-emo-zorn5999  ec-dimephmem-no1-glyzdap           6050  thpym-dis-imo-zdab6000  me2py-edia2-sem-npsdap             6051  bim-amn2-meo-bsdap6001  bim-amn2-no1-betapy                6052  hythpym-n2nme2n-5amo-psdab6002  am2py-trias-chexo-dfzdap           6053  pippy-25oxman2-napo-psdab6003  impy-24thizman2-aco-csdap          6054  2py-amn2-meo-psdab6004  amim-diphmep-oem-aspbzla           6055  gua-ams2-ocho-csdap6005  bhs-dimen-men-mezphe               6056  imhs-tetradi-mes-betainyl6006  pippy-ams2-mommo-glubzla           6057  bim-dimephmem-napo-bnsdap6007  morhs-am2-oem-nbetapy              6058  amim-m25thiz-imo-psdap6008  tolhs-tetradi-fo-ibsdap            6059  thpym-dimen-nmo-ibsdap6009  piraz-3diaz-fo-bhsdap              6060  bim-edian2-mes-psdap6010  hythpym-m25thiz-men-bphabs         6061  mam2py-eta-napo-bhsdab6011  piraz-amn3-5pho-betapy             6062  gua-pymea-5amo-dfzdap6012  dpam-m25thiz-no1-zdap              6063  piraz-amn2-mes-glyzdap6013  bhs-dimen-no2-zdabs                6064  imhs-mepipen2-cno-aspbzla6014  piraz-25thiz-aco-psdap             6065  thpym-amn2-no1-bnsdap6066  bhs-pipa-oeto-zdab                   6117  n2py-trias-eoco-aspbzla6067  am2py-trias-fo-ibsdap                6118  am2py-butn-no2-osdap6068  dhim-mea2s-cpeo-csdap                6119  npip-ams2-ocho-bhsdap6069  pippy-thizn-no1-csdap                6120  bimhs-dimephmem-5pho-asppha6070  bhs-mepazin-fo-aval                  6121  phpip-pyma2-5pho-betapy6071  pippy-am2-sem-nzdab                  6122  mam2py-edian2-chexo-zdabs6072  piraz-am3-sem-nbetameph              6123  bzl-25thizman2-mes-bphabs6073  bhs-amn2-5pho-bnsdap                 6124  amim-thizn-cpeo-psdab6074  nmor-24thiman2-fo-zdapee             6125  dhim-tridi-Apho-bhsdap6075  am2py-diphmem-imo-bhsdap             6126  chhs-am3-sem-nzdap6076  bhs-mepipe-5pho-bnsdap               6127  moegua-mepipen2-no1-bsdap6077  dmthpym-mepipen2-pheo-csdap          6128  imhs-pazin-meo-zdap6078  bimhs-dis-cno-zdabs                  6129  gua-dimen-mes-zdabs6079  imhs-amo2-mommo-psdab                6130  amim-ams2-no2-glyzdap6080  mam2py-indan2-emo-aspbzla            6131  bz-pentas-mes-asppha6081  me-pipa-hso-glyzdap                  6132  2py-pazin-meo-betapy6082  bhs-eta-mes-bnsdap                   6133  mepip-pipmea-cnmo-aspbzla6083  piraz-din-cno-ppsdap                 6134  nmhs-pipmeo-chexo-bhsdab6084  pippy-diphmem-fo-bhsdap              6135  chmhs-pyma2-daco-bhsdab6085  nmor-n2o2n-imo-aspbzla               6136  menim-edia2-sem-nzdab6086  2py-n24thiman-imo-zdab               6137  morhs-mepazin-oem-mezphe6087  pippy-pipmeo-4pho-aspibua            6138  ibhs-pipa-mes-bhsdap6088  amim-dimephmem-emo-bnsdap            6139  pippy-tetradi-chexo-zdabs6089  im-pipmea-fo-bhsdab                  6140  gua-eta2s-mecpo-csdap6090  2py-amn2-no1-psdap                   6141  bzl-am2-sem-nbetameph6091  bim-amn2-meo-bhsdap                  6142  impy-mepipe-meo-betapy6092  thpym-amn3-fo-zlys                   6143  bim-dimephmem-ocho-psdap6093  dhim-m24thizman2-5pho-betapy         6144  thpym-dimen-aco-glyzdap6094  impy-n24thiman-mes-zdabs             6145  2py-edian2-no2-bhsdap6095  bimhs-tridi-mes-zlys                 6146  hythpym-tetras-no2-bhsdab6096  bzl-pymea-no2-bphabs                 6147  2py-ams3-no1-betadcph6097  emnim-dis-meo-betadcph               6148  2pmhs-edian2-oem-betapy6098  hythpym-25oxman2-no2-glubzla         6149  emnim-ams2-meto-csdap6099  4pmhs-amn3-nmo-zdab                  6150  imhs-eta-meo-bnsdap6100  nim-butn-cno-glupha                  6151  im-25oxman2-imo-dfzdap6101  im-amn2-eoco-mezphe                  6152  nmor-pipa-mes-mezphe6102  bim-pazin-eoco-zdab                  6153  bimhs-diphmem-men-zdap6103  2py-pazin-mes-bnsdap                 6154  2py-m25oxman2-meo-osdap6104  bim-dimephmep-eoco-zdap              6155  imhs-mepipe-eoco-betapy6105  imhs-m25thiz-napo-betadcph           6156  z-thizn-fo-zdabs6106  menim-mepipe-5pho-betapy             6157  bimhs-butn-5pho-aspbzla6107  nmhs-eta-pro-bnsdap                  6158  amim-ams2-meo-oxal6108  thpym-thizn-5amo-aspibua             6159  piraz-dimephmem-no1-aspaba6109  amim-dimen-5amo-bnsdap               6160  me2py-amn3-men-psdab6110  bim-edian2-eoco-zdab                 6161  mepip-m25thiz-5amo-bhsdap6111  fthpym-dimephmep-meteto-             6162  thpym-24thiz-no2-bhsdab
  asppha                               6163  hythpym-25oxman2-ocho-asppha6112  nmhs-amn2-napo-bphabs                6164  hythpym-thizn-5pho-zdab6113  nmhs-din-peo-betapy                  6165  thpym-hexadi-eoco-bhsdab6114  dhim-pipmea-meo-glupha               6166  impy-pyma2-mecpo-betapy6115  deam-ms-oem-bsdap                    6167  mam2py-amn3-ocho-aspibua6116  thpym-mepipen2-no2-betadcph          6168  tolhs-mepipe-no1-aspbzla6169  2py-amn2-ocho-bsdap                6221  impy-pyma2-meo-aspaba6170  pyr-m24thiman2-eoco-mezphe         6222  thpym-amn3-5amo-psdap6171  2py-24thizman2-5pho-zdabs          6223  dmam-amn2-daco-glyzdap6172  dmbim-pipmes-5amo-psdab            6224  impy-pyma2-napo-zdab6173  im-propa2s-ocho-bhsdab             6225  phhs-dimephmep-meo-csdap6174  2pmhs-diphmep-imo-ppsdap           6226  4pmhs-diphmep-chexo-glyzdap6175  thpym-amn2-5pho-betapy             6227  dhim-pipmea-mommo-zdab6176  bimhs-pyma2-eoco-betainyl          6228  ibhs-mepipen2-imo-aspibua6177  bim-pazin-eoco-bsdap               6229  me2py-mepipe2-oem-npsdap6178  imhs-mepazin-mecpo-glupha          6230  2py-tridi-ocho-betaet6179  piraz-thizn-5amo-betainyl          6231  bim-edian2-ocho-betadcph6180  bimhs-m24thiman2-cpro-zlys         6232  2py-mepipe-mes-zdab6181  am2py-24thizman2-daco-zdabs        6233  moegua-ams2-emo-mezphe6182  dhim-mepipe-meo-psdapee            6234  bzl-n24thiman-imo-bnsdap6183  impy-m25thizman2-meo-bnsdap        6235  amim-mea2s-men-betadcph6184  am2py-pazi2n-napo-psdap            6236  nmor-mepazin-cno-bphabs6185  z-24thiz-5amo-zdab                 6237  mam2py-24thizman2-pheo-osdap6186  chmhs-tetradi-nmo-zorn             6238  prhs-am3-oem-nzdap6187  impy-pipmea-meo-csdap              6239  amthiaz-dimephmem-oem-psdab6188  imhs-pazin-5pho-bhsdap             6240  mam2py-thizn-chexo-betapy6189  dhim-trias-mes-betapy              6241  piraz-mepazin-oeto-csdap6190  cl3pyme-pazin-napo-glupha          6242  bimhs-mepipen2-imo-psdapee6191  phpip-am2-sem-nbetapy              6243  dpam-dimen-meo-bsdap6192  piraz-tetradi-nmo-osdap            6244  morhs-dio-imo-psdab6193  dhim-indan2-napo-zdabs             6245  am2py-diphmem-no1-psdab6194  imhs-pipmea-napo-bnsdap            6246  prhs-amn2-eoco-thizzdap6195  bhs-dimen-5pho-thizzdap            6247  am2py-mepazin-aco-bnsdap6196  piraz-2pazin-napo-aspbzla          6248  bim-mepipe-meo-zdap6197  bhs-edian2-oem-glubzla             6249  bhs-thizo-no2-bhsdab6198  am2py-dis-eoco-bsdap               6250  bhs-amn2-cno-psdab6199  pippy-dimen-oem-bphabs             6251  bhs-pnymea-chexo-zdap6200  thpym-edian2-eoco-bsdap            6252  mam2py-trias-chexo-bnsdap6201  edothpym-trias-mes-bnsdap          6253  bhs-diphmep-no2-glyzdap6202  im-2pazin-oem-dfzdap               6254  dhim-am2-oem-nbetabnaphth6203  dmbim-pymea-chexo-zdab             6255  2pmhs-pazin-mecpo-aspbzla6204  2py-ams3-oem-oxal                  6256  hythpym-24thizman2-ocho-6205  dhim-pymea-hso-betadcph                  bnsdap6206  chhs-3pazin-mecpo-zdabs            6257  chhs-pyma2-oem-bhsdab6207  phhs-dimen-aco-betainyl            6258  bzl-amn3-eoco-mezphe6208  imhs-pnymea-napo-bnsdap            6259  deam-tridi-no1-bnsdap6209  bim-m24thiz-no1-zdap               6260  edothpym-dimephmep-mes-6210  me2py-pipa-peo-zdap                      betadcph6211  mam2py-amo3-ocho-csdap             6261  bim-din-cno-bnsdap6212  pyrhs-amn2-chexo-bhsdab            6262  pippy-amo2-5pho-zdap6213  phpip-3pazin-napo-glyzdap          6263  phhs-24thiz-emo-zdap6214  pyrhs-diphmep-5pho-aspbzla         6264  bim-m24thizman2-cpro-bhsdab6215  dmam-dimephmep-men-zdab            6265  bim-24thizman2-imo-zdab6216  2py-pazin-5pho-bhsdab              6266  piraz-m24thizman2-paco-6217  mam2py-m25oxman2-meto-aspibua            aspibua6218  bimhs-24thizman2-5pho-mezphe       6267  impy-amn3-men-asppha6219  hythpym-dimen-imo-zdab             6268  bhs-amn2-eoco-psdab6220  dhim-m25thiz-napo-aspibua          6269  dmam-thizn-5pho-aspbzla6270  2py-mea-eoco-aspibua               6320  dhim-amn2-meto-mezphe6271  2py-propa2s-napo-bsdap             6321  bim-tetradi-ocho-bnsdap6272  am2py-pipa-5pho-glubzla            6322  bhs-am3-oem-npsdap6273  hythpym-mepipe-5pho-betadcph       6323  bim-trias-5amo-asppha6274  npip-pymea-emo-psdap               6324  moegua-amn3-imo-csdap6275  thpym-din-ocho-aspibua             6325  thpym-amn2-meo-bnsdap6276  pyr-25oxman2-emo-aspibua           6326  bhs-amo2-cpro-zdap6277  imhs-dio-cpeo-bsdap                6327  me2py-thizs-no1-bphabs6278  dmthpym-edian2-paco-zdab           6328  am4py-diphmem-napo-mezphe6279  gua-edian2-mes-asppha              6329  dhim-m24thizman2-5pho-zdab6280  imhs-mepipen2-5pho-ibsdap          6330  morhs-eta2s-no2-glyzdap6281  pyr-m24thizman2-ocho-aspaba        6331  bim-amn2-ocho-betapy6282  mam2py-dis-men-zdab                6332  n2py-dis-5pho-psdab6283  piraz-25oxman2-peo-oxal            6333  chmhs-pymea-oem-psdap6284  2py-pentas-imo-bhsdap              6334  mam2py-pipmea-mes-betapy6285  bimhs-trias-napo-asppha            6335  chhs-mepazin-mes-betadcph6286  mam2py-mepipen2-no2-bnsdap         6336  moegua-trias-ocho-betainyl6287  impy-mepazin-ocho-mezphe           6337  amim-tetradi-no2-mezphe6288  impy-pipmea-5amo-asppha            6338  chmhs-24oxman2-eoco-betadcph6289  bim-mepipen2-oem-zdab              6339  bhs-edian2-mes-zdap6290  bim-pazin-eoco-zdap                6340  hythpym-m24thizman2-6291  hythpym-m25thiz-paco-aval                meo-dfzdap6292  dhim-dimephmem-ocho-zdab           6341  menim-dis-aco-aspibua6293  ibhs-amo2-5amo-bsdap               6342  2py-eta-oem-bsdap6294  bhs-mepipe-no2-betapy              6343  me2py-hexas-5pho-betapy6295  2py-m25thiz-peo-bphabs             6344  tolhs-tetradi-5amo-psdap6296  piraz-m24thizman2-                 6345  mam2py-mepipen2-mes-dfzdap
  mommo-dfzdap                       6346  2py-mepazin-meo-betainyl6297  deam-dimephmem-emo-csdap           6347  hythpym-amo2-fo-betainyl6298  bim-pazin-no1-psdap                6348  thpym-pazin-oem-betapy6299  dhim-pentadi-meo-psdap             6349  me-pipmea-oem-bhsdab300   thpym-din-chexo-bhsdab             6350  imhs-pnymea-oem-bphabs6301  bim-edian2-no2-aspibua             6351  bhs-eta-no1-zdap6302  mam2py-edian2-no1-bsdap            6352  bimhs-hexadi-4amo-ppsdap6303  me2py-24thizman2-fo-aspibua        6353  bimhs-mepipe2-sem-nbetameph6304  hythpym-pipa-fo-zdabs              6354  bim-pipa-mecpo-bhsdab6305  2py-amn2-eoco-bhsdap               6355  pippy-eta-napo-psdab6306  phhs-edian2-mes-bnsdap             6356  n2py-dimen-5pho-aspbzla6307  imhs-amn3-5amo-bhsdab              6357  am2py-amn2-oem-aspibua6308  cl3pyme-25thizman2-oeto-           6358  ppy-24thiz-5pho-psdap
  bhsdap                             6359  bhs-trias-eoco-betadcph6309  hythpym-diphmem-men-bhsdap         6360  dmthpym-amo3-men-oxal6310  dhim-dich-chexo-aspbzla            6361  me2py-eta-ocho-zdabs6311  fthpym-propa2s-mes-betainyl        6362  dmam-pentas-meo-mezphe6312  mam2py-diphmep-emo-asppha          6363  bim-edian2-oem-psdab6313  amim-dich-meo-csdap                6364  am2py-25oxman2-chexo-zdabs6314  z-n2nme2n-men-zdapee               6365  phhs-25oxman2-aco-bhsdab6315  morhs-pipa-no2-betadcph            6366  am4py-pyma2-meo-betainyl6316  2py-pazin-ocho-bhsdap              6367  2py-24thizman2-fo-betadcph6317  bim-m25oxman2-no1-bphabs           6368  thpym-amn2-imo-bhsdap6318  mam2py-props-imo-betainyl          6369  deam-24thiz-baeo-bphabs6319  ppy-m24thizman2-peo-betapy         6370  gua-amn3-5pho-aspibua6371  piraz-dipch-5pho-zdap               6423  nmhs-thizn-fo-zdabs6372  2py-pipmes-meo-mezphe               6424  bim-pyma2-5pho-psdab6373  am4py-dimephmem-cno-aspibua         6425  amim-24thizman2-ocho-psdab6374  impy-mepipen2-oem-aspbzla           6426  hythpym-mepipen2-emo-zdap6375  chmhs-hexas-imo-bnsdap              6427  mam2py-25oxman2-chexo-asppha6376  ibhs-dimen-5pho-aspibua             6428  imhs-edian2-meo-psdab6377  me2py-dimephmem-ocho-mezphe         6429  am-amn3-imo-zdabs6378  imhs-tetradi-hso-asppha             6430  hythpym-diphmem-no2-aspibua6379  amim-ams2-imo-betainyl              6431  4pmhs-tridi-fo-betadcph6380  2py-n24thiman-oem-aspaba            6432  thpym-m25thiman2-nmo-zdabs6381  gua-trias-napo-psdab                6433  mam2py-pyma2-no1-zdabs6382  mam2py-mepazin-meteto-glyzdap       6434  mam2py-pipmes-imo-psdab6383  bimhs-pnymea-baeo-bhsdap            6435  phpip-m25thiz-mes-glubzla6384  impy-amn3-men-psdab                 6436  mam2py-diphmep-mommo-glubzla6385  me2py-ams3-fo-aspibua               6437  bimhs-thizn-pheo-mezphe6386  hythpym-n2nme2n-napo-betainyl       6438  dhim-pnymea-5pho-asppha6387  pyr-amn2-no2-bhsdab                 6439  nmhs-amn2-5pho-glyzdap6388  2py-eta-no1-bsdap                   6440  2py-eta-5pho-bsdap6389  piraz-mepipe-fo-zdab                6441  hythpym-m25oxman2-chexo-osdap6390  bzl-m25thiman2-meteto-zdap          6442  pippy-pnymea-chexo-betaet6391  chmhs-pyma2-napo-betaet             6443  edothpym-25oxman2-ocho-zdabs6392  am-24thiman-mes-oxal                6444  me2py-amn2-imo-psdab6393  thpym-edian2-oem-zdab               6445  me2py-pnymea-eoco-aspbzla6394  am2py-mepipe-napo-bhsdap            6446  thpym-edian2-meo-zdab6395  chhs-pyma2-emo-betadcph             6447  bhs-edian2-ocho-psdab6396  ec-m25thiz-meo-bhsdap               6448  ppy-tridi-chexo-bnsdap6397  piraz-diphmem-emo-betainyl          6449  dmam-24thiz-meo-aspibua6398  emnim-diaz-5pho-bhsdap              6450  imhs-m25thiz-eoco-thizzdap6399  npip-mepazin-5pho-osdap             6451  am2py-pentas-oeto-bnsdap6400  phpip-amn2-emo-zdap                 6452  piraz-pazin-eoco-bnsdap6401  npip-24thizman2-napo-ibsdap         6453  imhs-pipmeo-chexo-bnsdap6402  am2py-3diaz-mes-psdap               6454  n2py-dich-5amo-aspibua6403  ibhs-eta-eoco-zdap                  6455  imhs-amn2-mes-psdap6404  pyraz-amn3-ocho-osdap               6456  amim-amo2-pyo-mezphe6405  thpym-amn2-no1-psdab                6457  pippy-amn2-cnmo-aspibua6406  cl3pyme-tridi-eoco-bnsdap           6458  thpym-pazin-eoco-bnsdap6407  am2py-edian2-emo-bphabs             6459  tolhs-thizn-peo-zdabs6408  bim-mepipe-mes-zdab                 6460  thpym-pyma2-mes-bphabs6409  am2py-25oxman2-4amo-psdapee         6461  pippy-mepipen2-men-zdabs6410  pippy-eta-5pho-mezphe               6462  am2py-dis-fo-zdap6411  mam2py-2pazin-meto-bsdap            6463  impy-pipa-oem-betadcph6412  2py-amn3-fo-betadcph                6464  phpip-thizn-no1-betadcph6413  imhs-pnymea-napo-aspbzla            6465  dhim-tridi-mecpo-zdab6414  n2py-propa2s-ocho-aspbzla           6466  im-m25thiman2-no2-zdabs6415  z-25thiz-5amo-zdab                  6467  bimhs-tridi-5amo-zdap6416  gua-edian2-men-betainyl             6468  2py-pazin-meo-bhsdap6417  ec-din-mmen-ppsdap                  6469  ppy-thizn-pheo-psdapee6418  dhim-tridi-no2-aspbzla              6470  thpym-tetradi-no2-mezphe6419  am2py-trias-men-bphabs              6471  bim-m25thiman2-oeto-glyzdap6420  2py-amn2-no2-bsdap                  6472  amim-m24thizman2-eoco-psdap6421  dhim-mepazin-pyo-betapy             6473  amim-dimephmep-meo-csdap6422  2py-amn2-no2-bnsdap                 6474  impy-trias-imo-zdap6475  imhs-amn3-nmo-bsdap                 6527  am2py-diaz-daco-zdap6476  pyrhs-pazin-napo-aspibua            6528  ec-tetradi-meo-bphabs6477  dhim-trias-oem-osdap                6529  pippy-pazi2n-no2-zdap6478  pippy-diphmep-chexo-psdap           6530  imhs-mepipen2-ocho-aspaba6479  hythpym-mepipen2-hso-csdap          6531  dmbim-amn2-meo-zorn6480  edothpym-eta2s-oem-zorn             6532  bhs-dis-ocho-csdap6481  mam2py-diphmem-aco-bhsdap           6533  imhs-ams2-no2-aspibua6482  dhim-amn3-oem-psdapee               6534  nmor-m24thizman2-no2-zdab6483  hythpym-edian2-fo-betainyl          6535  dhim-thizn-napo-zdab6484  n2py-props-mes-zdab                 6536  phpip-24thiz-emo-aspibua6485  bhs-din-ocho-asppha                 6537  nmor-dimephmep-no2-csdap6486  bim-3pazin-5amo-bnsdap              6538  am2py-dimephmem-meo-bhsdap6487  chhs-din-cpeo-aspbzla               6539  ppy-mepazin-cpeo-csdap6488  2py-pazin-5pho-zdab                 6540  bhs-props-mecpo-bphabs6489  mam2py-m24thizman2-mmen-oxal        6541  thpym-pnymea-napo-glyzdap6490  bhs-mepipe-mes-bhsdap               6542  moegua-pipmea-oem-bphabs6491  bim-m25thiz-imo-osdap               6543  nim-diphmep-chexo-bsdap6492  pippy-3diaz-mes-csdap               6544  bimhs-pipmea-hso-zdap6493  imhs-pnymea-no2-bsdap               6545  thpym-diphmep-men-zdabs6494  hythpym-dimen-napo-ppsdap           6546  am2py-eta-eoco-betainyl6495  2py-pnymea-meo-bhsdab               6547  am-m24thizman2-no2-zdabs6496  bhs-2pazin-cpro-zdap                6548  dhim-mepazin-eoco-bhsdap6497  2py-mepipe-oem-zdab                 6549  bim-pipmeo-men-betadcph6498  dhim-pyma2-emo-bnsdap               6550  z-propa2s-no1-csdap6499  dhim-tetradi-no1-bsdap              6551  z-m25thiz-no1-betainyl6500  mam2py-dis-daco-asppha              6552  thpym-m25thiz-men-betadcph6501  bim-eta-mes-psdap                   6553  me-m24thizman2-imo-bsdap6502  bhs-eta-oem-bhsdap                  6554  dhim-edian2-ocho-csdap6503  bhs-mepipe-5pho-psdab               6555  pippy-dio-imo-bsdap6504  bimhs-diphmep-fo-asppha             6556  me2py-amn3-emo-bnsdap6505  piraz-mepipe-emo-dfzdap             6557  hythpym-eta-5amo-bnsdap6506  amim-diphmep-eoco-csdap             6558  am2py-tridi-fo-asppha6507  2py-edian2-ocho-betapy              6559  fthpym-pipa-5amo-bsdap6508  thpym-amn2-eoco-psdap               6560  pyr-mepipe-meteto-zdapee6509  me2py-pipmea-no1-betainyl           6561  bhs-tetradi-fo-psdab6510  dhim-25oxman2-mecpo-zdabs           6562  amim-dis-fo-betapy6511  imhs-m25thiz-men-betainyl           6563  bhs-dich-men-tsdap6512  amim-trias-meto-bnsdap              6564  nim-dimephmep-ocho-glyzdap6513  thpym-amn2-meo-zdap                 6565  bimhs-dich-mecpo-zdabs6514  bim-amn2-no2-bsdap                  6566  hythpym-pyma2-meo-bphabs6515  hythpym-dis-5amo-zdab               6567  phhs-edia2-sem-nbetapy6516  pippy-2pazin-imo-osdap              6568  mepip-diphmep-nmo-csdap6517  phhs-25oxman2-imo-tsdap             6569  amthiaz-ams2-chexo-osdap6518  bim-mepipe-eoco-psdab               6570  nim-m25thiz-imo-betadcph6519  amim-dimephmep-oem-psdab            6571  dpam-m25oxman2-emo-asppha6520  piraz-n2o2n-pro-bhsdab              6572  imhs-tetradi-4pho-psdap6521  mam2py-butn-baeo-glyzdap            6573  pippy-pymea-eoco-osdap6522  amim-edia2-oem-nzdab                6574  pippy-m24thizman2-oeto-zdabs6523  bim-diphmep-eoco-glyzdap            6575  deam-am3-sem-nzdap6524  piraz-m24thizman2-emo-csdap         6576  am2py-pymea-hso-bsdap6525  amim-tetras-ocho-aspbzla            6577  mam2py-props-5pho-bphabs6526  thpym-dimephmep-no2-csdap           6578  pyrhs-diphmep-men-betadcph6579  bim-amn2-oem-bsdap                  6631  am2py-pipmea-5pho-mezphe6580  impy-n2o2n-emo-bphabs               6632  dhim-ams2-emo-zdab6581  thpym-dis-cpeo-betadcph             6633  thpym-mea-fo-aspibua6582  chhs-diphmem-5amo-asppha            6634  am2py-diphmem-5pho-psdap6583  moegua-tridi-pro-aspibua            6635  me2py-amn2-nmo-psdab6584  impy-dis-napo-betapy                6636  hythpym-din-meo-aspibua6585  chhs-pipmea-ocho-zdap               6637  thpym-pnymea-napo-psdap6586  phhs-pipmea-5amo-zdab               6638  am2py-dimen-imo-dfzdap6587  bimhs-24thiman-aco-dfzdap           6639  piraz-mepazin-meo-aspibua6588  dhim-edian2-chexo-zdap              6640  me2py-pazin-napo-bphabs6589  thpym-amn2-meo-psdab                6641  2py-edian2-meo-zdab6590  phpip-24oxman2-meto-zorn            6642  imhs-trias-meteto-glyzdap6591  piraz-thizo-5amo-zdapee             6643  bim-dimephmep-no2-zdap6592  thpym-amn3-4pho-betapy              6644  amim-m25thizman2-oem-bhsdab6593  impy-mea2s-chexo-bsdap              6645  bimhs-amo2-no2-zdap6594  amim-dis-eoco-aval                  6646  nim-thizn-oem-zdabs6595  bim-pnymea-emo-mezphe               6647  bhs-tetradi-cnmo-bhsdap6596  menim-dimephmep-imo-bhsdab          6648  me2py-mepipen2-cpeo-aspibua6597  thpym-dimephmem-mmen-betadcph       6649  gua-m25thizman2-men-dfzdap6598  bz-tridi-cpro-dfzdap                6650  thpym-m25thiz-imo-zdabs6599  bim-trias-chexo-dfzdap              6651  me2py-mepipe2-sem-nzdab6600  bzl-trias-napo-aspibua              6652  piraz-mepipen2-mes-glyzdap6601  am4py-am3-sem-nbetapy               6653  moegua-pazi2n-emo-bnsdap6602  thpym-eta-eoco-betapy               6654  z-am2-oem-nbetameph6603  impy-pentadi-ocho-aspbzla           6655  impy-pipmea-pyo-bhsdap6604  mam2py-dimephmem-aco-dfzdap         6656  nmhs-mea-meo-dfzdap6605  z-24thiz-5pho-dfzdap                6657  mepip-pentadi-5amo-zdabs6606  hythpym-pipa-cno-bhsdab             6658  prhs-24thiz-aco-bsdap6607  emnim-25thiman2-daco-psdap          6659  piraz-amn3-cno-betapy6608  am2py-trias-no1-betapy              6660  piraz-pazi2n-imo-glyzdap6609  thpym-eta-no1-psdab                 6661  bim-eta-no1-zdap6610  imhs-tetradi-napo-bhsdap            6662  dmthpym-pazin-imo-psdab6611  dpam-3diaz-napo-bnsdap              6663  dmthpym-amn3-meo-psdab6612  bimhs-24thiz-no2-bnsdap             6664  deam-mepipen2-mommo-dfzdap6613  thpym-tetradi-no2-aspibua           6665  amim-m24oxman2-meo-bhsdab6614  piraz-pipmea-eoco-bphabs            6666  imhs-m24thizman2-eoco-dfzdap6615  bhs-am3-sem-npsdap                  6667  pyrhs-n24thiman-chexo-6616  amthiaz-edian2-ocho-zdab                  betadcph6617  bim-eta-oeto-psdab                  6668  bhs-tridi-mes-thizzdap6618  4pmhs-n2o2n-eoco-zorn               6669  thpym-dich-pro-glyzdap6619  imhs-m25thiz-4amo-betapy            6670  phpip-ams2-5pho-bsdap6620  hythpym-amn2-emo-aspibua            6671  amim-pyma2-imo-zdab6621  bz-pnymea-no2-aval                  6672  amim-pazin-eoco-psdap6622  pippy-pentas-fo-zdab                6673  pippy-mepazin-pheo-aspbzla6623  amim-edian2-cno-asppha              6674  bimhs-pnymea-mommo-csdap6624  emnim-m25thiz-napo-csdap            6675  me2py-pazin-daco-dfzdap6625  bim-24thizman2-imo-zdap             6676  bhs-tridi-meo-glyzdap6626  piraz-ms-5amo-oxal                  6677  bzl-din-no1-aspibua6627  npip-mepipen2-ocho-psdap            6678  im-pipa-emo-bhsdap6628  bhs-edian2-ocho-zdab                6679  hythpym-3pazin-ocho-psdab6629  phpip-pipa-men-bphabs               6680  nim-hexas-fo-aval6630  thpym-25thiz-men-bhsdap             6681  ibhs-pyma2-oeto-psdap6682  dhim-pipa-oeto-zdabs               6733  2py-amo3-eoco-bsdap6683  me2py-pipa-no1-betainyl            6734  amim-24thizman2-mes-oxal6684  impy-24thiz-chexo-aspbzla          6735  me2py-diphmep-5amo-zdab6685  c13pyme-24thiman-no2-bnsdap        6736  dpam-din-mecpo-asppha6686  pippy-mepazin-chexo-zdap           6737  imhs-amo2-5pho-betadcph6687  dpam-tridi-fo-aspbzla              6738  edothpym-m25thiz-mecpo-asppha6688  thpym-25oxman2-men-zdab            6739  imhs-pazin-no1-zdab6689  impy-dis-oeto-bnsdap               6740  imhs-n24thiman-meo-bnsdap6690  2py-diphmem-daco-psdab             6741  npip-24thizman2-5pho-aspibua6691  deam-dimephmem-oem-bhsdap          6742  dhim-am3diaz-daco-bsdap6692  bhs-eta-no2-psdab                  6743  dmam-amo2-oeto-bhsdap6693  thpym-mea2s-mes-betapy             6744  bimhs-24thizman2-emo-csdap6694  am2py-mea-ocho-bhsdap              6745  menim-propn-5pho-zdab6695  am4py-thizo-imo-betainyl           6746  pippy-butn-fo-bsdap6696  mam2py-25thizman2-ocho-            6747  bhs-mepipen2-daco-aspibua
  glyzdap                            6748  mepip-pipmea-mes-bhsdab6697  piraz-24thizman2-fo-bhsdap         6749  z-pipmea-napo-zdap6698  2py-dio-napo-glyzdap               6750  bzl-diphmem-no1-betadcph6699  phpip-dimephmem-oem-bnsdap         6751  2py-ams2-fo-asppha6700  pyrhs-trias-emo-glyzdap            6752  chhs-din-5pho-csdap6701  impy-dimen-men-psdap               6753  pyr-dich-fo-betainyl6702  dhim-24thizman2-men-bnsdap         6754  menim-pipmea-men-psdab6703  2py-pipa-5pho-bhsdap               6755  am-mepipe-eoco-asppha6704  impy-dimephmem-5amo-psdab          6756  me2py-pipa-napo-mezphe6705  imhs-amn2-eoco-zdab                6757  phpip-pyma2-ocho-bnsdap6706  moegua-props-oem-betadcph          6758  imhs-edian2-no1-zdab6707  hythpym-dis-5amo-tsdap             6759  phhs-pazin-pro-aspibua6708  thpym-m25thiz-meo-betaet           6760  2py-eta-mes-bhsdap6709  tolhs-diaz-napo-bsdap              6761  phpip-tetradi-imo-aspibua6710  mam2py-mepazin-ocho-ibsdap         6762  bhs-eta-no2-psdap6711  hythpym-24thiz-cpro-glyzdap        6763  tolhs-amo2-no2-psdap6712  amim-tridi-fo-psdab                6764  2py-pazin-5pho-psdap6713  bhs-amo2-eoco-glyzdap              6765  amim-m25thiz-emo-betadcph6714  me2py-amn2-nmo-psdap               6766  z-diphmem-eoco-glubzla6715  chhs-pentadi-no2-bphabs            6767  pippy-mepipe2-sem-nbeta34-6716  mam2py-24thizman2-pyo-bsdap              dimeoph6717  hythpym-dimen-5pho-zdapee          6768  z-diaz-5pho-aspbzla6718  edothpym-am2-sem-nzdab             6769  imhs-pazin-ocho-bnsdap6719  bim-eta-meteto-betadcph            6770  am-din-no2-asppha6720  dhim-mepipen2-chexo-betapy         6771  2py-amn2-eoco-psdap6721  2py-24thiz-no1-betainyl            6772  pyraz-dimephmep-4pho-osdap6722  menim-mepipen2-no1-zdab            6773  dhim-thizn-imo-mezphe6723  am2py-amn3-5amo-zdabs              6774  bhs-25oxman2-mes-betapy6724  piraz-edia2-oem-nzdab              6775  amthiaz-pipmea-napo-bhsdab6725  hythpym-mepazin-hso-psdap          6776  morhs-pipa-no2-psdap6726  2py-pazin-meo-bsdap                6777  nim-24thiz-imo-zlys6727  bimhs-tetradi-hso-aspibua          6778  bz-propn-5amo-zdap6728  imhs-amn3-eoco-ppsdap              6779  moegua-din-men-aspibua6729  am2py-24thizman2-men-zdabs         6780  chmhs-dipch-daco-bsdap6730  dhim-amo2-cno-betainyl             6781  pyr-tridi-mes-csdap6731  impy-pyma2-eoco-bnsdap             6782  chhs-eta-chexo-bphabs6732  mam2py-amo2-ocho-zdab              6783  dhim-3diaz-ocho-betaet6784  pippy-m24thiman2-napo-bsdap         6836  ec-mea-emo-betaet6785  2py-edian2-no2-bsdap                6837  pippy-amn2-oem-zdabs6786  piraz-2pazin-fo-zdap                6838  dhim-m24oxman2-meo-zdabs6787  hythpym-pentas-imo-mezphe           6839  amim-dimephmem-cno-psdap6788  bhs-amn3-chexo-dfzdap               6840  ppy-ams3-imo-csdap6789  2py-dimen-meo-tsdap                 6841  bim-eta-imo-bsdap6790  impy-m24thizman2-daco-tsdap         6842  bim-dis-eoco-zorn6791  tolhs-pyma2-eoco-zdabs              6843  pippy-trias-chexo-csdap6792  imhs-dis-pyo-psdap                  6844  4pmhs-tridi-eoco-betainyl6793  dmthpym-trias-no2-oxal              6845  pyrhs-24oxman2-no1-bsdap6794  piraz-pipa-men-osdap                6846  2pmhs-m24thiz-ocho-aspbzla6795  amim-24thiz-emo-bphabs              6847  nmhs-pipmea-5pho-bphabs6796  bim-amn3-ocho-aspbzla               6848  2py-ams2-emo-psdap6797  bimhs-pazin-emo-betapy              6849  menim-3diaz-hso-aval6798  imhs-25oxman2-chexo-psdapee         6850  imhs-edian2-eoco-bsdap6799  imhs-amo2-baeo-asppha               6851  bimhs-tridi-fo-zdab6800  thpym-ams3-fo-bnsdap                6852  me2py-diphmem-napo-glubzla6801  impy-amn2-chexo-bphabs              6853  impy-n24thiman-imo-psdap6802  amim-pyma2-men-bsdap                6854  me2py-edian2-napo-bsdap6803  2py-eta-5pho-psdap                  6855  bhs-edian2-chexo-psdap6804  me2py-mepipe2-sem-npsdap            6856  bhs-hexas-napo-zdap6805  bhs-mepipe-no1-bsdap                6857  npip-pnymea-ocho-zorn6806  bhs-amn2-ocho-betapy                6858  2py-mepipe2-oem-nbeta34-6807  bim-eta-aco-oxal                          dimeoph6808  impy-edia2-oem-nbetameph            6859  pyr-3diaz-5amo-zdabs6809  impy-diphmep-pro-psdap              6860  bhs-din-5pho-aspibua6810  chmhs-pymea-emo-asppha              6861  bim-dimen-5pho-mezphe6811  amim-mepipe2-sem-npsdap             6862  imhs-pentas-men-bhsdap6812  pyraz-m25thiz-no2-dfzdap            6863  amim-dis-emo-csdap6813  pippy-tridi-no2-bhsdap              6864  am2py-25oxman2-chexo-csdap6814  amim-mepipe-no1-psdab               6865  bimhs-din-chexo-bsdap6815  pyr-n2o2n-5pho-zdabs                6866  bimhs-m25thiman2-mes-betaet6816  imhs-24thiz-men-zdap                6867  am2py-dio-no2-psdab6817  impy-m24thizman2-mes-oxal           6868  amim-diaz-mommo-aspibua6818  me2py-pnymea-imo-bhsdap             6869  pyrhs-amn2-pyo-zdabs6819  imhs-eta-5pho-bhsdap                6870  hythpym-props-daco-betainyl6820  bim-24thiman-meteto-aspbzla         6871  ppy-24thiman-meo-csdap6821  ibhs-am2-sem-nzdab                  6872  thpym-propa2s-fo-betaet6822  hythpym-amn3-baeo-mezphe            6873  deam-dimen-fo-zdab6823  imhs-edian2-eoco-bnsdap             6874  imhs-amn2-oem-zdap6824  mam2py-tetradi-5pho-zdap            6875  am2py-din-meo-zdap6825  am2py-amn3-eoco-betadcph            6876  piraz-pipa-emo-psdap6826  hythpym-amn3-meo-aspibua            6877  ppy-amn2-oem-aspibua6827  piraz-2pazin-5pho-bhsdab            6878  ibhs-ams2-men-aspaba6828  fthpym-pnymea-chexo-mezphe          6879  2pmhs-pymea-5pho-psdap6829  pippy-m25thiz-emo-asppha            6880  dmbim-tridi-chexo-zdap6830  hythpym-mea2s-cnmo-betainyl         6881  2py-mepipe-eoco-zdab6831  amim-eta-5amo-bhsdab                6882  dmthpym-pymea-mes-zdab6832  me2py-amo2-napo-aspibua             6883  hythpym-pymea-eoco-bnsdap6833  me-dimephmem-no2-aspibua            6884  impy-diphmep-napo-zdap6834  mepip-3pazin-5pho-psdap             6885  thpym-pazin-no1-bsdap6835  2py-amn2-ocho-zdap                  6886  mam2py-mepipen2-5amo-asppha6887  pippy-25oxman2-napo-bhsdap          6939  ibhs-eta-no1-betainyl6888  bzl-n2o2n-meo-zdabs                 6940  hythpym-25oxman2-4pho-bhsdap6889  pyrhs-mepipen2-5pho-psdap           6941  pippy-pymea-ocho-dfzdap6890  mam2py-dio-imo-aspibua              6942  nim-din-eoco-psdap6891  nmor-am3-sem-nbetapy                6943  impy-edian2-chexo-bhsdab6892  mam2py-25thiz-fo-psdab              6944  imhs-diphmem-napo-dfzdap6893  piraz-propa2s-baeo-aspbzla          6945  impy-amo2-imo-zdabs6894  mam2py-thizo-5amo-tsdap             6946  impy-24thiz-no2-bphabs6895  amim-mepipe-meo-bsdap               6947  amthiaz-24thizman2-no1-psdab6896  impy-hexadi-no1-csdap               6948  bhs-25oxman2-emo-psdap6897  dpam-pipmea-meo-psdap               6949  am-diphmep-5pho-zdab6898  bhs-dimephmem-napo-mezphe           6950  me2py-tridi-mes-zdabs6899  am2py-diphmep-5pho-mezphe           6951  4pmhs-amo2-5 amo-asppha6900  dhim-din-oem-bhsdap                 6952  imhs-pymea-5amo-bnsdap6901  z-pnymea-pro-mezphe                 6953  nmor-pnymea-no2-bhsdap6902  hythpym-n2nme2n-hso-glyzdap         6954  4pmhs-pazin-meo-asppha6903  thpym-amn2-5pho-psdab               6955  me-dimephmep-cpeo-betadcph6904  dhim-dimephmem-peo-bhsdap           6956  2py-mepipen2-emo-betapy6905  fthpym-amo2-imo-aspbzla             6957  bhs-tetradi-mecpo-aspbzla6906  mam2py-25oxman2-mecpo-psdap         6958  imhs-25oxman2-napo-glupha6907  piraz-pazin-napo-thizzdap           6959  piraz-24thizman2-mmen-6908  bim-amn2-ocho-bsdap                       betadcph6909  piraz-m24thizman2-mes-bphabs        6960  piraz-ams2-men-csdap6910  thpym-dimephmem-mommo-bsdap         6961  thpym-pazin-emo-betainyl6911  bimhs-pipa-meo-bhsdab               6962  bim-mepipe-oem-betapy6912  me2py-hexas-5pho-psdap              6963  2py-mepipe-eoco-psdab6913  bim-dis-meo-psdap                   6964  thpym-amn3-5pho-oxal6914  hythpym-24thiz-men-glyzdap          6965  thpym-edian2-mes-zdap6915  hythpym-mepipen2-no1-psdap          6966  fthpym-thizn-4amo-psdapee6916  4pmhs-edian2-5amo-zdab              6967  mam2py-diaz-no1-zdap6917  phhs-ams2-pro-psdapee               6968  imhs-amn2-ocho-zdap6918  am2py-pipa-chexo-psdab              6969  thpym-24thiman2-cpeo-oxal6919  bim-mepipe-no2-psdab                6970  bimhs-tridi-napo-zdap6920  ec-am3-sem-npsdap                   6971  imhs-2pazin-emo-glyzdap6921  mam2py-propn-imo-bnsdap             6972  dmam-24thiman2-no2-csdap6922  impy-dich-pro-ppsdap                6973  hythpym-m24thizman2-oem-zlys6923  bim-mepipe-eoco-psdap               6974  bhs-25thiz-oem-aspibua6924  am2py-ams2-cpro-psdapee             6975  am2py-edian2-meo-aspbzla6925  imhs-ms-imo-asppha                  6976  thpym-pipmeo-5amo-bhsdab6926  hythpym-m25oxman2-men-zorn          6977  impy-amn3-mes-asppha6927  imhs-25oxman2-baeo-csdap            6978  impy-pyma2-5amo-bsdap6928  thpym-pazin-meo-bsdap               6979  morhs-hexas-ocho-dfzdap6929  dmthpym-tridi-no1-zdabs             6980  am2py-am3-sem-nbetameph6930  amim-thizn-napo-bhsdab              6981  bhs-propn-eoco-zdabs6931  menim-trias-men-zlys                6982  fthpym-25oxman2-meo-bnsdap6932  deam-2pazin-pro-mezphe              6983  dhim-pentadi-4amo-glubzla6933  deam-mepazin-4amo-zorn              6984  pippy-pipa-mommo-psdab6934  pippy-tetradi-chexo-bnsdap          6985  dmbim-thizn-meo-bphabs6935  bhs-eta-mes-psdab                   6986  npip-edian2-5pho-tsdap6936  chhs-amn2-no2-betainyl              6987  nim-tridi-pheo-betainyl6937  bhs-pipmea-ocho-glubzla             6988  amthiaz-mepipe2-sem-npsdap6938  tolhs-ams2-pyo-zdapee               6989  emnim-pnymea-imo-bhsdap6990  pippy-pipmes-mommo-glyzdap          7042  imhs-edian2-meo-zdap6991  am2py-pnymea-men-bhsdab             7043  2py-pipmea-5amo-betapy6992  piraz-din-imo-bhsdab                7044  am-tridi-mes-dfzdap6993  ppy-pazin-men-zdap                  7045  piraz-propa2s-oem-ibsdap6994  am2py-tridi-chexo-mezphe            7046  bim-2pazin-no2-betapy6995  am-eta-no2-bnsdap                   7047  mam2py-mea2s-5amo-bsdap6996  am2py-trias-meo-ppsdap              7048  ibhs-edian2-oem-psdab6997  imhs-dimephmep-5pho-bphabs          7049  dpam-diphmem-no1-betapy6998  thpym-pazin-oem-psdab               7050  hythpym-edia2-sem-nbetapy6999  hythpym-edian2-4pho-psdap           7051  n2py-24oxman2-mes-aspaba7000  bhs-edian2-no1-bnsdap               7052  thpym-dis-aco-aspibua7001  2py-eta-5amo-aval                   7053  hythpym-24thiman2-mes-zdap7002  pippy-diphmep-5amo-bhsdab           7054  dhim-diphmep-5pho-bnsdap7003  bhs-pipa-napo-dfzdap                7055  2py-pentas-5amo-betapy7004  imhs-pazin-mes-psdab                7056  moegua-25oxman2-oem-betadcph7005  thpym-din-chexo-glyzdap             7057  dhim-thizs-mes-aspibua7006  me2py-pentadi-ocho-bphabs           7058  hythpym-24thiz-mes-csdap7007  fthpym-25oxmn2-mommo-betapy         7059  gua-tridi-mes-bhsdap7008  bim-hexas-emo-betainyl              7060  2pmhs-edian2-meo-asppha7009  z-dimen-men-aspbzla                 7061  am2py-diphmem-napo-zdap7010  me-diphmem-5pho-bphabs              7062  2py-24thiz-imo-psdab7011  piraz-24thiz-eoco-aspibua           7063  bim-mepipe-no1-bhsdap7012  am2py-tetradi-5pho-zdabs            7064  bz-mepipen2-fo-betainyl7013  thpym-pipmea-ocho-betainyl          7065  bim-mepipe-mes-bhsdap7014  bim-diphmep-emo-asppha              7066  gua-amo2-emo-glyzdap7015  ec-tetradi-ocho-asppha              7067  piraz-24thizman2-cnmo-asppha7016  n2py-m24thiz-oem-mezphe             7068  mepip-tetradi-5pho-zdab7017  impy-ms-napo-psdab                  7069  hythpym-diphmem-emo-bnsdap7018  z-m25thiman2-no1-bnsdap             7070  bim-pazi2n-aco-psdapee7019  im-m25oxman2-baeo-asppha            7071  n2py-din-mommo-zdabs7020  pippy-pyma2-napo-asppha             7072  bimhs-diphmem-mecpo-oxal7021  deam-dimephmep-5pho-dfzdap          7073  piraz-mepipe-no1-bsdap7022  deam-dis-paco-bhsdap                7074  am2py-mepipen2-no2-bhsdab7023  piraz-pymea-no1-betadcph            7075  dpam-mepipen2-napo-glyzdap7024  bhs-24thizman2-mes-zdap             7076  nmhs-pazi2n-men-betadcph7025  bimhs-pazin-no1-mezphe              7077  imhs-m25oxman2-men-oxal7026  am2py-pyma2-imo-bsdap               7078  thpym-amn2-oem-bhsdap7027  pippy-2pazin-4pho-bsdap             7079  piraz-amo3-fo-psdab7028  bim-edian2-mes-bsdap                7080  mam2py-diphmem-oem-zdap7029  nmor-mepazin-5amo-ppsdap            7081  nim-butn-oeto-bphabs7030  moegua-mepipe-ocho-zdabs            7082  tolhs-2pazin-fo-zdab7031  2py-m24thizman2-cpro-zdap           7083  2py-mea2s-no1-bsdap7032  me2py-pyma2-cpro-aspbzla            7084  phhs-edia2-sem-nbetabnaphth7033  bim-pazin-ocho-psdab                7085  me2py-pnymea-baeo-psdab7034  pippy-edian2-no2-bsdap              7086  bhs-edian2-meo-psdab7035  bim-thizs-mommo-bnsdap              7087  amim-dimephmem-chexo-mezphe7036  am2py-pyma2-napo-glyzdap            7088  dmbim-pyma2-pheo-bsdap7037  nmor-24thizman2-ocho-bphabs         7089  bim-mepipen2-fo-aspaba7038  npip-pymea-imo-bsdap                7090  2py-mepipen2-5pho-aspibua7039  mam2py-trias-napo-bhsdab            7091  ec-diphmnem-imo-aspbzla7040  impy-m24thizman2-4amo-betapy        7092  ec-trias-no2-betainyl7041  mam2py-mepipe-mes-bphabs            7093  piraz-m25oxman2-no1-bhsdab7094  ibhs-pymea-no2-ppsdap              7145  thpym-dis-5pho-aval7095  pippy-2pazin-meo-betainyl          7146  amim-amn3-ocho-ibsdap7096  n2py-diphmem-5pho-aspaba           7147  bim-dis-men-bhsdap7097  me2py-din-oem-bsdap                7148  nim-hexadi-napo-dfzdap7098  dhim-dimephmep-meo-aspibua         7149  pyr-tridi-men-zdap7099  fthpym-indan2-imo-psdapee          7150  2py-m25thiz-no1-aspbzla7100  2py-edian2-eoco-zdab               7151  bhs-edia2-sem-nbeta34dimeoph7101  nmor-dimephmep-no2-bnsdap          7152  2py-edia2-oem-nbetameph7102  bhs-pazin-meo-betapy               7153  amim-24thiz-mes-zdap7103  ec-din-eoco-betadcph               7154  dhim-pnymea-chexo-bnsdap7104  am2py-hexadi-no2-glyzdap           7155  bhs-25oxman2-5pho-betainyl7105  ec-pyma2-5amo-zdab                 7156  tolhs-dio-5amo-glyzdap7106  bhs-edian2-meo-zdap                7157  me-din-meo-betadcph7107  bhs-pyma2-emo-aspbzla              7158  impy-mepazin-chexo-bphabs7108  bim-3pazin-5pho-aspibua            7159  2py-ms-emo-zdap7109  ec-diphmep-emo-bnsdap              7160  n2py-diphmep-oeto-betainyl7110  me-pnymea-meo-psdap                7161  2py-25oxman2-no2-bsdap7111  chmhs-amn3-mes-bhsdap              7162  am2py-pazi2n-meto-betapy7112  amim-mepipe-4pho-zdap              7163  npip-pipa-imo-bhsdap7113  2pmhs-dipch-mes-betainyl           7164  dhim-ams2-pro-zdabs7114  hythpym-pazi2n-ocho-bhsdab         7165  imhs-eta-ocho-zdap7115  dmam-dis-4amo-zlys                 7166  dmbim-mepipen2-oem-zdap7116  bimhs-tridi-oeto-bhsdab            7167  thpym-eta-no2-psdab7117  bim-dimephmep-no2-betaet           7168  2py-mepipe-no2-csdap7118  bhs-24thiz-pro-psdab               7169  dpam-24oxman2-ocho-dfzdap7119  emnim-pipmea-no1-glubzla           7170  imhs-amn2-mes-glupha7120  fthpym-amo2-eoco-bsdap             7171  dhim-m24thizman2-oem-psdap7121  bzl-amo2-napo-glyzdap              7172  bimhs-amn3-eoco-aval7122  am2py-m25thiz-men-thizzdap         7173  me2py-dimephmem-men-bhsdap7123  am2py-ams2-5amo-betadcph           7174  ec-pentadi-fo-bphabs7124  me2py-dimephmem-emo-mezphe         7175  bimhs-din-pheo-psdap7125  im-am2-sem-nbetabnaphth            7176  bzl-thizs-fo-betapy7126  me2py-eta2s-emo-psdap              7177  phpip-24thizman2-no1-bphabs7127  2py-pazin-cnmo-bhsdap              7178  bim-eta-oem-bsdap7128  dmthpym-amo2-ocho-psdab            7179  thpym-edian2-oem-bhsdap7129  piraz-mepipe2-oem-nzdap            7180  mepip-din-paco-psdab7130  hythpym-m25thiz-chexo-             7181  thpym-eta-ocho-zdap
  thizzdap                           7182  bimhs-pentadi-daco-asppha7131  2py-n2o2n-chexo-betainyl           7183  bhs-25oxman2-imo-bsdap7132  imhs-amn2-4amo-aspaba              7184  dmbim-mepazin-cnmo-aspbzla7133  am-pipmea-hso-betainyl             7185  dhim-dis-mes-psdap7134  bimhs-m24thiman2-eoco-zdab         7186  imhs-25oxman2-eoco-aval7135  chhs-pazin-oeto-psdap              7187  pippy-dis-oeto-zdap7136  am2py-dimen-meo-aspbzla            7188  emnim-mepazin-4amo-betapy7137  fthpym-dimephmep-cpro-zdap         7189  piraz-24thizman2-oem-dfzdap7138  piraz-dimephmep-fo-zdabs           7190  piraz-mepipe2-sem-nzdap7139  bhs-ams2-eoco-zdab                 7191  imhs-pymea-napo-oxal7140  am-tridi-eoco-zdapee               7192  bim-25oxman2-napo-dfzdap7141  am2py-pipa-no1-psdap               7193  deam-25oxman2-4pho-glyzdap7142  bhs-ms-emo-aspaba                  7194  mam2py-dimephmem-ocho-betapy7143  chmhs-m25thiman2-5amo-zdap         7195  4pmhs-25thizman2-no2-psdap7144  mam2py-dimen-fo-zdab               7196  thpym-24thizman2-5amo-bsdap7197  amim-ams2-oem-bhsdab                7248  im-m25thiz-chexo-psdab7198  bhs-ams2-meo-betapy                 7249  thpym-pyma2-chexo-zdab7199  2py-pipmes-5amo-mezphe              7250  pippy-dio-mes-dfzdap7200  imhs-eta-meo-psdap                  7251  mam2py-pyma2-no2-aspbzla7201  bim-pazin-meo-zdab                  7252  am2py-amo2-mommo-ppsdap7202  im-m25thizman2-mes-zdap             7253  2py-tetradi-5pho-osdap7203  imhs-pnymea-men-bhsdab              7254  mam2py-mepipen2-meo-psdab7204  pyraz-m25oxman2-imo-bhsdab          7255  ec-pazi2n-eoco-betaet7205  dhim-ams3-mes-aspibua               7256  imhs-n2nme2n-eoco-betainyl7206  dhim-thizn-ocho-betainyl            7257  imhs-mepipe-no2-psdap7207  bim-props-meo-aspibua               7258  menim-amn2-cnmo-ibsdap7208  piraz-24thizman2-mes-bhsdap         7259  me2py-m25thiman2-ocho-glubzla7209  thpym-mepipe2-oem-nbetab            7260  amim-25oxman2-fo-psdapee
  naphth                              7261  thpym-ms-5amo-bhsdab7210  im-am3-oem-nzdab                    7262  bhs-pazin-5amo-zdab7211  thpym-amn2-eoco-bhsdap              7263  imhs-n2nme2n-peo-bhsdap7212  dmbim-dimen-no2-bphabs              7264  me2py-eta-emo-glyzdap7213  dhim-mepipe-napo-bhsdab             7265  impy-pipa-napo-zdab7214  impy-m25thiz-5pho-psdap             7266  am-mepipen2-no1-bnsdap7215  bim-edian2-5pho-bnsdap              7267  bimhs-mepazin-imo-betapy7216  dhim-trias-imo-csdap                7268  am2py-dimephmep-men-bphabs7217  amthiaz-n2o2n-emo-asppha            7269  imhs-pazin-no1-betapy7218  z-dimephmep-no2-zdap                7270  pyraz-pyma2-5pho-bnsdap7219  nmor-mepazin-chexo-csdap            7271  me2py-pipmes-oem-aspbzla7220  bimhs-mepipen2-chexo-aspbzla        7272  emnim-mepipe2-sem-npsdap7221  hythpym-m24thiman2-mes-dfzdap       7273  thpym-butn-ocho-bsdap7222  bim-tridi-pheo-bhsdab               7274  n2py-din-eoco-betadcph7223  bim-edia2-oem-npsdap                7275  dhim-mepipen2-no2-bhsdap7224  imhs-tridi-5amo-bphabs              7276  emnim-din-peo-asppha7225  bim-diphmem-cpeo-zdab               7277  n2py-dimephmem-no1-bhsdap7226  emnim-m25thiz-imo-betadcph          7278  impy-pyma2-no2-dfzdap7227  2py-din-mes-bnsdap                  7279  bimhs-thizo-cpro-zdab7228  thpym-mepipe-ocho-psdap             7280  am4py-dimephmem-5pho-zdab7229  chmhs-mepipe-no1-betadcph           7281  ppy-mepazin-eoco-betapy7230  bim-mepipe2-sem-nzdap               7282  mam2py-m24thiman2-pro-zdap7231  ec-dimen-paco-oxal                  7283  2py-24oxman2-mes-zdab7232  cl3pyme-mepazin-men-bnsdap          7284  hythpym-dimephmem-paco-ppsdap7233  imhs-tetras-meteto-aspibua          7285  hythpym-n2o2n-chexo-zdab7234  piraz-3diaz-eoco-dfzdap             7286  hythpym-mea2s-mes-bhsdab7235  dhim-amn2-no2-csdap                 7287  bim-m25thiz-chexo-aval7236  chhs-pyma2-chexo-psdap              7288  nmhs-pazi2n-chexo-betadcph7237  am2py-m25thiz-5amo-csdap            7289  dhim-dimephmem-ocho-bsdap7238  bimhs-m25thiz-chexo-zdab            7290  me2py-pazin-eoco-aspibua7239  me2py-mepipe-mes-ppsdap             7291  bimhs-25oxman2-pheo-psdapee7240  bimhs-mepazin-oem-csdap             7292  pippy-25oxman2-cpro-psdap7241  me2py-24oxman2-chexo-zdap           7293  dhim-pipa-emo-bhsdab7242  dmthpym-3pazin-fo-zdab              7294  amim-25oxman2-men-bnsdap7243  thpym-m25thiz-meo-zdap              7295  dmthpym-dimephmep-5amo-bsdap7244  morhs-3pazin-meo-glyzdap            7296  ppy-edian2-no2-osdap7245  nim-mepipen2-5pho-mezphe            7297  am4py-25thiman2-5amo-mezphe7246  bhs-tetras-5pho-bhsdab              7298  amim-pazin-chexo-csdap7247  hythpym-dimen-no1-betainyl          7299  dhim-pazi2n-chexo-betapy7300  phpip-amo2-5amo-bhsdab            7352  bimhs-pnymea-5pho-aspaba7301  hythpym-24thiz-napo-zdabs         7353  thpym-diphmem-oem-glyzdap7302  me2py-edia2-oem-nbetabnaphth      7354  thpym-diaz-no2-psdap7303  mam2py-mepipe-cpro-glubzla        7355  nmhs-trias-no2-tsdap7304  edothpym-pymea-chexo-aspaba       7356  bimhs-dimephmem-5amo-aspbzla7305  z-pipmea-oem-betapy               7357  mam2py-tetradi-oem-mezphe7306  bim-amn2-no2-bhsdap               7358  bim-edia2-sem-nzdap7307  thpym-m25thiz-mecpo-psdab         7359  imhs-pymea-eoco-oxal7308  gua-trias-pro-betapy              7360  moegua-dimephmem-5pho-glyzdap7309  2py-pazin-emo-psdab               7361  bim-amn3-napo-zdab7310  dhim-pipmeo-no2-bsdap             7362  me2py-mepipe-napo-bsdap7311  am-pymea-4amo-zdap                7363  imhs-edian2-eoco-mezphe7312  imhs-pazin-eoco-psdap             7364  hythpym-diphmem-mecpo-bhsdab7313  hythpym-props-fo-psdab            7365  4pmhs-trias-mes-bhsdab7314  bz-pipa-imo-bphabs                7366  imhs-am3-oem-nbeta34dimeoph7315  bhs-edian2-eoco-psdab             7367  2pmhs-trias-mes-mezphe7316  amim-trias-mommo-glyzdap          7368  amim-pipa-ocho-zdapee7317  chhs-am3-sem-nzdap                7369  me2py-dimen-no1-psdab7318  gua-25thiz-meo-aspibua            7370  nim-pnymea-meto-zdabs7319  dmthpym-24thizman2-no1-aval       7371  chmhs-amo2-eoco-asppha7320  piraz-3diaz-5amo-zdab             7372  bim-25oxman2-napo-bhsdap7321  2py-amo2-5amo-betadcph            7373  pippy-n24thiman-5amo-bnsdap7322  bim-eta-oem-bnsdap                7374  pyrhs-am2-oem-nbetameph7323  dhim-pnymea-men-betapy            7375  imhs-trias-5pho-bhsdab7324  imhs-amn2-5pho-bhsdap             7376  morhs-eta-emo-ppsdap7325  piraz-pnymea-cno-betainyl         7377  am2py-m25thizman2-no2-betapy7326  bhs-amn2-no2-betapy               7378  bhs-pazin-eoco-bsdap7327  pippy-diphmep-cpeo-betapy         7379  mepip-mepipen2-chexo-zdap7328  deam-thizn-5amo-aspibua           7380  menim-am3-oem-nbeta34dimeoph7329  bimhs-m24thiman2-cnmo-mezphe      7381  piraz-am3-oem-nbeta34dimeoph7330  bhs-diphmem-eoco-betainyl         7382  2py-eta-no2-psdab7331  imhs-eta-ocho-bhsdap              7383  2py-eta-meo-betapy7332  2py-amo2-meo-mezphe               7384  2py-mepipe-chexo-zdabs7333  dpam-pnymea-emo-betadcph          7385  nmhs-pazin-aco-asppha7334  impy-24thizman2-mes-bsdap         7386  bim-pazin-meo-bsdap7335  piraz-pymea-fo-csdap              7387  2py-mepipe-no2-zdap7336  menim-25oxman2-peo-bnsdap         7388  imhs-pymea-napo-zdab7337  bhs-m25thiz-no2-zdabs             7389  amthiaz-pipmea-daco-bsdap7338  hythpym-thizn-ocho-bhsdab         7390  amim-3pazin-no1-betaet7339  edothpym-pymea-fo-zdapee          7391  imhs-pazin-eoco-bsdap7340  piraz-diphmep-mes-bsdap           7392  bim-dis-cno-zdabs7341  2py-am2-oem-nzdap                 7393  pippy-thizn-chexo-betadcph7342  2py-trias-chexo-bhsdap            7394  2py-mepipen2-eoco-psdab7343  mam2py-pymea-imo-aspibua          7395  bim-thizn-5amo-psdab7344  bimhs-n2o2n-no1-glyzdap           7396  dhim-tetras-imo-bnsdap7345  deam-eta-no2-zdabs                7397  im-pnymea-chexo-aspbzla7346  bimhs-diphmem-fo-aspbzla          7398  amim-eta-ocho-bhsdab7347  dhim-n2nme2n-imo-psdap            7399  me2py-pipa-napo-bnsdap7348  2py-eta-meo-zdap                  7400  piraz-amn3-mes-psdap7349  bimhs-dimephmep-nmo-osdap         7401  am2py-pymea-emo-bsdap7350  2py-amn2-meto-zorn                7402  edothpym-dimen-nmo-ppsdap7351  thpym-pazin-eoco-zdab             7403  me2py-24thiman-chexo-zdabs7404  dpam-eta2s-ocho-asppha             7453  bhs-mepazin-men-zdap7405  am2py-m25thiz-eoco-betainyl        7454  im-amn2-ocho-zdabs7406  ppy-mepipen2-5amo-betapy           7455  2py-trias-fo-bnsdap7407  nim-pipa-men-bphabs                7456  thpym-trias-oem-bphabs7408  thpym-mepipen2-meo-zdabs           7457  nmor-pymea-men-csdap7409  am2py-25oxman2-oeto-zdabs          7458  phpip-pyma2-ocho-betapy7410  thpym-tetradi-fo-betapy            7459  piraz-n24thiman-no2-betapy7411  me2py-amo2-emo-thizzdap            7460  piraz-ams2-no2-aspibua7412  bimhs-pnymea-imo-psdab             7461  2py-mepipe-eoco-bnsdap7413  am4py-pazin-napo-psdab             7462  2pmhs-mepazin-oeto-bsdap7414  am2py-mepazin-napo-bphabs          7463  fthpym-pipmea-imo-bhsdab7415  piraz-pazin-imo-zdab               7464  impy-pazin-meo-psdab7416  2py-pymea-no2-aspbzla              7465  dpam-thizn-meo-mezphe7417  impy-pipa-pheo-dfzdap              7466  mam2py-tridi-eoco-glyzdap7418  menim-pnymea-no2-aspaba            7467  pippy-m24thiman2-ocho-glyzdap7419  prhs-dimephmep-pheo-zdap           7468  bim-amn2-fo-zdab7420  pippy-pipmea-men-oxal              7469  2py-amo2-oeto-ibsdap7421  phpip-dimephmem-imo-mezphe         7470  nim-25thizman2-meteto-7422  bhs-n24thiman-imo-zdap                   betadcph7423  me2py-25thiz-mmen-zdabs            7471  am2py-dimephmem-eoco-aspibua7424  bim-pipa-5pho-glyzdap              7472  emnim-indan2-fo-zdapee7425  cl3pyme-m24thiman2-pyo-            7473  bim-mepipe-5pho-psdab
  thizzdap                           7474  mam2py-pipa-oem-csdap7426  me2py-dimephmem-5amo-aspibua       7475  pippy-pipmea-emo-psdap7427  pippy-diphmep-eoco-bphabs          7476  tolhs-24thiman2-chexo-glyzdap7428  impy-din-napo-csdap                7477  nim-mepipe2-sem-nzdab7429  hythpym-trias-pheo-aspibua         7478  me2py-dis-chexo-zdab7430  2py-eta-no1-bnsdap                 7479  edothpym-pipmeo-5amo-psdab7431  fthpym-eta-napo-psdap              7480  thpym-edian2-eoco-bsdap7432  nmhs-tetradi-eoco-aspaba           7481  am2py-pnymea-ocho-csdap7433  mam2py-m24thizman2-chexo-          7482  am2py-ams2-imo-betaet
  betaet                             7483  nmhs-dis-cpro-bphabs7434  2py-tridi-emo-mezphe               7484  dhim-amo2-eoco-bhsdap7435  imhs-m24thizman2-no1-dfzdap        7485  pippy-dimephmep-4pho-bhsdab7436  menim-amo3-ocho-zdab               7486  am2py-din-imo-bphabs7437  mam2py-24oxman2-meo-betaet         7487  bim-mepipe-oem-bsdap7438  dhim-amn2-napo-bnsdap              7488  2py-eta-fo-oxal7439  2py-propa2s-meteto-thizzdap        7489  chhs-thizn-daco-betainyl7440  dmam-mepipen2-no2-bsdap            7490  mam2py-ams2-5pho-psdab7441  fthpym-dis-pheo-zdabs              7491  dpam-tetradi-mes-dfzdap7442  hythpym-m25thizman2-oem-           7492  nmhs-n2o2n-5amo-bhsdab
  betainyl                           7493  imhs-tridi-napo-betapy7443  dhim-diphmep-emo-psdap             7494  2py-edian2-5pho-bnsdap7444  me2py-dimephmem-imo-betapy         7495  mam2py-dimen-peo-aspbzla7445  piraz-pipmea-oem-betadcph          7496  dpam-edian2-mes-betadcph7446  hythpym-diphmep-no2-bnsdap         7497  piraz-pyma2-daco-mezphe7447  dpam-edian2-pro-psdab              7498  amthiaz-24thiz-fo-psdab7448  mam2py-amo2-men-csdap              7499  imhs-dimen-men-bhsdap7449  edothpym-24thiman-aco-glyzdap      7500  phhs-trias-5amo-zdap7450  imhs-am3-sem-nbetabnaphth          7501  thpym-24thiz-pyo-psdab7451  piraz-eta-meo-psdab                7502  thpym-eta-no2-betapy7452  thpym-24thiman-no1-bnsdap          7503  bhs-tridi-mes-bnsdap7504  hythpym-mepazin-pro-bsdap           7554  bim-mepipe2-sem-nbetapy7505  dhim-m25thizman2-5pho-psdab         7555  bimhs-mepipen2-5amo-bsdap7506  ppy-ms-fo-aspibua                   7556  dmbim-tetradi-meo-aspbzla7507  2py-pazin-eoco-bsdap                7557  2pmhs-dimephmep-5amo-bhsdap7508  thpym-eta-5pho-psdab                7558  2py-dich-pyo-bhsdap7509  dmthpym-diphmep-mes-aspibua         7559  2py-amn2-eoco-psdab7510  bhs-diphmep-men-betapy              7560  imhs-eta-ocho-aspbzla7511  nmhs-25oxman2-men-dfzdap            7561  me-am3-oem-nbeta34dimeoph7512  morhs-thizn-ocho-aspbzla            7562  mam2py-amo2-ocho-ibsdap7513  dhim-amn2-eoco-aspbzla              7563  dpam-25thiz-chexo-bnsdap7514  imhs-pyma2-imo-mezphe               7564  2py-mepipe-5pho-psdap7515  pyrhs-dis-eoco-betapy               7565  impy-dich-eoco-bhsdap7516  z-amn2-mmen-betadcph                7566  piraz-m24thizman2-cno-csdap7517  ma2py-25oxman2-oem-osdap            7567  am2py-pymea-no2-psdap7518  hythpym-dimen-eoco-zdap             7568  prhs-thizn-no2-bsdap7519  prhs-25oxman2-5pho-csdap            7569  me2py-tetradi-mommo-betadcph7520  imhs-m24thiz-mecpo-psdap            7570  nmor-pazi2n-oem-bhsdap7521  dpam-edian2-meo-dfzdap              7571  z-pyma2-5pho-asppha7522  bhs-eta-no1-bnsdap                  7572  pyraz-dis-peo-aval7523  hythpym-diphmem-napo-zdab           7573  am-m25thiz-meto-bnsdap7524  pippy-mepipen2-napo-asppha          7574  gua-pnymea-no1-aspbzla7525  2py-pipmea-fo-bhsdab                7575  nmhs-amn3-ocho-betadcph7526  amim-24thizman2-cnmo-zdab           7576  bimhs-dio-oem-bnsdap7527  bim-eta-eoco-psdap                  7577  bim-amn2-eoco-bnsdap7528  dpam-mepipen2-mommo-betainyl        7578  me2py-25oxman2-oeto-bhsdap7529  bhs-mepipe-oem-bhsdap               7579  gua-dipch-imo-bsdap7530  pippy-pyma2-napo-bhsdap             7580  bimhs-tetradi-cpro-glyzdap7531  bhs-mepipe-5pho-bhsdap              7581  piraz-mepipe-mes-zdab7532  hythpym-24thizman2-eoco-            7582  am2py-mepipen2-no2-betapy
  bnsdap                              7583  hythpym-hexadi-cpeo-zdabs7533  amim-m25oxman2-mmen-betadcph        7584  piraz-trias-4amo-asppha7534  edothpym-diphmem-fo-betaet          7585  bhs-mepazin-no1-bhsdab7535  bim-mepipe-ocho-bsdap               7586  pippy-din-imo-betapy7536  bim-eta-ocho-zdab                   7587  thpym-m24thiman2-5amo-csdap7537  imhs-edian2-no2-psdap               7588  imhs-dimephmep-cpro-zdab7538  bhs-pipmea-napo-dfzdap              7589  ibhs-diphmep-no2-glyzdap7539  bimhs-tridi-cpeo-dfzdap             7590  impy-pymea-no2-psdab7540  bim-amn2-eoco-zdap                  7591  dhim-ams3-5pho-mezphe7541  dmbim-thizn-men-bhsdap              7592  amim-pymea-no1-asppha7542  2py-pazin-mes-bhsdap                7593  bhs-pipa-5pho-glyzdap7543  2py-amn2-5pho-betapy                7594  dmbim-m24thizman2-oeto-zdab7544  mepip-trias-ocho-psdab              7595  am2py-24thizman2-aco-aspbzla7545  hythpym-thizs-imo-asppha            7596  dhim-pipmeo-5pho-osdap7546  prhs-tetradi-5pho-dfzdap            7597  me2py-am3-sem-npsdap7547  ppy-am3diaz-chexo-asppha            7598  impy-diphmem-nmo-glyzdap7548  am-pipmeo-hso-asppha                7599  dhim-24thizman2-eoco-psdab7549  dmbim-dimephmem-mommo-              7600  bimhs-24thiz-emo-betainyl
  thizzdap                            7601  me2py-pazin-meo-zdab7550  bimhs-pipa-no1-zdabs                7602  impy-trias-men-dfzdap7551  bhs-pazin-5pho-bhsdap               7603  am2py-dimephmep-meo-osdap7552  impy-3pazin-no2-betadcph            7604  phhs-am3-sem-nbetapy7553  morhs-am3-oem-nbetapy               7605  bz-dimephmep-mecpo-zdab7606  mam2py-dis-5pho-asppha              7657  impy-n24thiman-ocho-mezphe7607  impy-tetradi-cno-dfzdap             7658  piraz-din-5amo-glyzdap7608  impy-am3-sem-nzdap                  7659  pippy-dimephmem-fo-oxal7609  2py-props-no1-tsdap                 7660  mam2py-dimephmep-no2-zdap7610  deam-mepazin-5pho-psdap             7661  me2py-dimephmep-ocho-bnsdap7611  bim-edian2-5pho-psdap               7662  piraz-am3diaz-no1-zdab7612  bim-diphmem-emo-bnsdap              7663  bimhs-m25oxman2-ocho-glyzdap7613  piraz-hexas-hso-aspaba              7664  thpym-tetras-cno-bphabs7614  z-dimephmem-ocho-zdap               7665  imhs-24thizman2-eoco-zlys7615  hythpym-am3diaz-meto-glyzdap        7666  pippy-tetradi-emo-bnsdap7616  mepip-mepipe2-sem-nbeta34-          7667  nmhs-m25thiman2-ocho-zdapee
  dimeoph                             7668  bimhs-24oxman2-no1-bnsdap7617  2pmhs-25thizman2-pro-glyzdap        7669  amim-ams2-cpeo-bhsdap7618  nim-ams2-fo-tsdap                   7670  me2py-dis-oem-psdap7619  pyrhs-pipa-no2-betapy               7671  impy-m25thiz-men-betadcph7620  pippy-amn2-emo-psdap                7672  bhs-mepipe-oem-zdab7621  piraz-diphmep-imo-betainyl          7673  bhs-mepipe-mes-betapy7622  pyr-m24thiz-napo-betaet             7674  bzl-amn2-mes-aspibua7623  thpym-propn-napo-mezphe             7675  pyraz-din-5amo-psdap7624  amim-m24oxman2-emo-psdapee          7676  bz-m24thiman2-chexo-csdap7625  pippy-pymea-fo-aspibua              7677  hythpym-ams2-men-thizzdap7626  amim-mepipen2-men-zdabs             7678  mam2py-diphmem-no1-zdabs7627  dhim-mepipe-napo-glyzdap            7679  bim-dich-meo-zdabs7628  me2py-din-mecpo-betadcph            7680  impy-edian2-5pho-aspibua7629  bimhs-pnymea-cno-aspbzla            7681  imhs-edian2-no1-bsdap7630  thpym-pipmes-men-bsdap              7682  ec-25oxman2-nmo-mezphe7631  am2py-mepazin-ocho-dfzdap           7683  ec-din-oem-aspibua7632  impy-am2-sem-nbetabnaphth           7684  4pmhs-pazin-paco-psdap7633  nmhs-amn3-5pho-betadcph             7685  piraz-edia2-oem-nbetabnaphth7634  pippy-edia2-oem-npsdap              7686  morhs-edian2-5amo-aspbzla7635  amthiaz-pipmea-no2-betainyl         7687  dhim-ams2-fo-betadcph7636  hythpym-pipmea-meteto-zdabs         7688  deam-m25thiz-emo-bphabs7637  hythpym-eta-5amo-psdap              7689  cl3pyme-24thizman2-4amo-7638  emnim-mepazin-no2-csdap                   ppsdap7639  pippy-tetradi-5amo-bhsdab           7690  dhim-din-mommo-glyzdap7640  chmhs-thizn-mes-psdap               7691  me-m24thizman2-meo-glyzdap7641  imhs-eta-no1-zdap                   7692  dmam-25thizman2-4amo-thizzdap7642  z-m25thiz-cpeo-bhsdap               7693  bim-am2-oem-nbetameph7643  amim-diphmep-no2-glyzdap            7694  pippy-24thiz-meteto-psdab7644  4pmhs-dimen-imo-csdap               7695  2py-am3-oem-nbeta34dimeoph7645  imhs-eta-5pho-psdap                 7696  2py-amn2-eoco-betapy7646  me2py-pipa-5pho-zdab                7697  dmbim-pentadi-no2-bsdap7647  npip-amn2-no2-bhsdap                7698  dhim-24thiz-meo-asppha7648  me2py-25oxman2-imo-bsdap            7699  impy-thizn-ocho-mezphe7649  prhs-pazin-mes-glubzla              7700  thpym-mepipe-oem-psdab7650  imhs-mepipe-5pho-bhsdap             7701  pippy-n24thiman-5amo-psdap7651  hythpym-diphmem-ocho-bsdap          7702  hythpym-dimephmem-men-7652  morhs-dimen-men-aval                      betainyl7653  thpym-pipa-hso-asppha               7703  gua-25thiman2-paco-betainyl7654  thpym-pazin-ocho-psdap              7704  bim-pazin-eoco-betapy7655  impy-pipmea-oem-csdap               7705  thpym-mepipe-5pho-bphabs7656  dpam-dis-eoco-bsdap                 7706  2py-24thiz-napo-zlys7707  impy-pipmes-mes-aspbzla            7759  me2py-edian2-5amo-betainyl7708  bhs-thizn-meo-ibsdap               7760  z-edia2-sem-nzdap7709  ppy-tridi-chexo-mezphe             7761  chhs-mepipe-chexo-zdap7710  thpym-tridi-imo-betainyl           7762  dhim-25oxman2-men-csdap7711  chhs-24thiz-no1-aval               7763  impy-mea2s-5pho-zdap7712  chmhs-trias-men-mezphe             7764  bimhs-dis-mes-bnsdap7713  am2py-diphmep-ocho-dfzdap          7765  bhs-amn2-meo-betapy7714  pippy-edian2-imo-zdabs             7766  thpym-25oxman2-no2-zdap7715  deam-24thiz-no1-dfzdap             7767  bim-edian2-oem-betapy7716  nmor-amn3-cpeo-bnsdap              7768  bim-dimen-hso-betapy7717  bhs-m25thiz-chexo-zdabs            7769  mam2py-pnymea-fo-mezphe7718  dhim-dimen-4pho-betapy             7770  prhs-pymea-ocho-csdap7719  gua-24thiman-aco-zdap              7771  2py-amn2-no1-zdab7720  mam2py-diphmem-oem-bhsdap          7772  hythpym-mepipe-meteto-psdapee7721  am4py-mea2s-napo-aspbzla           7773  hythpym-3diaz-cpro-zdap7722  amim-pyma2-daco-thizzdap           7774  deam-pnymea-no1-bhsdab7723  amim-dimephmep-5amo-betadcph       7775  phhs-pyma2-no2-zdabs7724  bimhs-m25thiz-mes-zdabs            7776  mam2py-ams2-paco-psdab7725  me2py-thizs-fo-asppha              7777  bhs-edian2-mes-bhsdap7726  am2py-din-eoco-betapy              7778  pippy-thizs-no1-betaet7727  bim-edian2-pheo-zdap               7779  nim-pazin-imo-ibsdap7728  bhs-mepipe-mes-bnsdap              7780  nmor-amn3-men-mezphe7729  moegua-24thiman2-emo-csdap         7781  menim-pipmes-meo-bphabs7730  imhs-eta-eoco-bnsdap               7782  dhim-dimephmep-imo-dfzdap7731  imhs-mepipen2-no2-oxal             7783  z-24thiz-aco-betaet7732  thpym-edia2-oem-nbetapy            7784  bhs-amn3-mmen-zdap7733  ec-eta-meo-aspbzla                 7785  edothpym-hexas-mes-csdap7734  hythpym-amn2-eoco-aval             7786  amim-diphmem-ocho-csdap7735  n2py-pymea-meo-zdap                7787  n2py-24thiz-mommo-bphabs7736  amim-24thizman2-no2-bsdap          7788  piraz-pazin-eoco-dfzdap7737  thpym-pnymea-ocho-betadcph         7789  bhs-mepazin-no2-betainyl7738  2py-24oxman2-cnmo-bhsdap           7790  ec-m24thizman2-mecpo-glyzdap7739  me2py-amo2-no2-aspbzla             7791  hythpym-amo3-oem-zdap7740  menim-dipch-mes-betapy             7792  n2py-pymea-cnmo-zdabs7741  n2py-thizo-no1-betainyl            7793  2py-diphmem-chexo-psdap7742  bhs-mepipe-eoco-bsdap              7794  bzl-din-no2-glyzdap7743  moegua-eta-emo-zdabs               7795  bim-amn2-no2-psdap7744  me-m25thiz-mes-bphabs              7796  mam2py-eta2s-no1-zdabs7745  bzl-dio-aco-bnsdap                 7797  2py-edian2-no1-zdab7746  2py-n2o2n-meto-dfzdap              7798  dhim-eta-baeo-ppsdap7747  thpym-dimen-no2-ibsdap             7799  bim-dis-mecpo-betapy7748  ec-mepipen2-fo-bnsdap              7800  me2py-pipa-oem-aspibua7749  am2py-pyma2-imo-zdap               7801  2py-m24thizman2-5pho-asppha7750  dmam-thizn-4amo-bhsdab             7802  pyr-propn-peo-mezphe7751  imhs-edian2-5pho-betapy            7803  2py-24thiz-napo-ibsdap7752  bhs-24thiz-5amo-psdab              7804  thpym-butn-meo-asppha7753  am2py-dimephmem-no2-bhsdab         7805  pippy-mepipen2-emo-zdab7754  bhs-pazin-emo-betapy               7806  bim-pyma2-no1-mezphe7755  im-mepipe2-oem-npsdap              7807  amim-mepipen2-no1-bhsdab7756  bim-tetras-cpeo-psdap              7808  mam2py-mepipen2-ocho-aspbzla7757  amim-amo2-oem-betaet               7809  imhs-pyma2-no1-betadcph7758  n2py-trias-men-betainyl            7810  imhs-dimephmep-imo-bhsdab7811  ibhs-pipmea-4pho-mezphe            7862  mam2py-24thiz-ocho-bhsdap7812  mam2py-dimephmem-5pho-psdap        7863  piraz-amn3-mes-zdab7813  bimhs-24thizman2-chexo-            7864  thpym-24thiz-imo-aspbzla
  betadcph                           7865  hythpym-tridi-no1-asppha7814  2pmhs-dimephmep-5pho-psdap         7866  amthiaz-mepipe-oem-betainyl7815  hythpym-pyma2-oem-csdap            7867  imhs-amo2-imo-zdabs7816  2py-tetras-emo-bhsdap              7868  am2py-m24oxman2-no1-ppsdap7817  imhs-mepipe-ocho-bnsdap            7869  mam2py-ams2-fo-bsdap7818  dhim-amo2-emo-csdap                7870  fthpym-ams3-pheo-zdap7819  bimhs-mepipe-mommo-glyzdap         7871  me2py-pazin-pheo-bsdap7820  imhs-pazin-eoco-psdab              7872  gua-pnymea-cpeo-betadcph7821  dpam-mepazin-chexo-asppha          7873  amim-amo2-no1-bhsdab7822  impy-pyma2-imo-dfzdap              7874  prhs-edian2-4pho-bhsdab7823  am2py-eta-mes-psdap                7875  2py-amn3-mommo-bphabs7824  hythpym-tridi-5pho-oxal            7876  nim-edian2-meto-csdap7825  mam2py-dimephmep-emo-zdap          7877  2py-thizn-pheo-bphabs7826  bhs-dimephmep-men-bphabs           7878  nim-mepipe2-sem-nbeta34-7827  emnim-24thizman2-mmen-bhsdab             dimeoph7828  hythpym-trias-emo-zdab             7879  pyrhs-ams2-mmen-mezphe7829  ibhs-mepazin-4amo-ibsdap           7880  emnim-diphmem-no1-betainyl7830  dmthpym-diphmem-5amo-glyzdap       7881  dpam-hexadi-aco-betainyl7831  dhim-mepipe-oem-psdab              7882  hythpym-indan2-napo-glyzdap7832  imhs-3diaz-fo-aspbzla              7883  imhs-mepipe-eoco-bnsdap7833  me2py-diphmep-no1-betadcph         7884  am2py-mepazin-no1-mezphe7834  bim-diphmep-emo-zdap               7885  pippy-pyma2-napo-psdab7835  bimhs-diphmep-peo-zdabs            7886  bhs-mepipe-emo-dfzdap7836  bhs-tetradi-imo-betapy             7887  ppy-edian2-oeto-bhsdap7837  me2py-trias-mommo-betadcph         7888  2py-diphmem-no2-mezphe7838  bzl-m25thiz-mmen-dfzdap            7889  dhim-amn2-eoco-bphabs7839  pippy-tetradi-mommo-csdap          7890  pyrhs-mepazin-chexo-bphabs7840  dhim-edia2-sem-nbetabnaphth        7891  bim-pazin-oem-psdap7841  moegua-eta-pro-betainyl            7892  am2py-dimen-imo-betadcph7842  bhs-ams3-no1-psdab                 7893  ppy-ams3-cnmo-betainyl7843  impy-pipa-peo-betaet               7894  bzl-mepazin-hso-betadcph7844  edothpym-n2nme2n-mes-bhsdab        7895  amim-pyma2-emo-zdabs7845  n2py-thizn-eoco-psdab              7896  hythpym-ms-no1-aspaba7846  cl3pyme-hexas-men-glyzdap          7897  bim-mepazin-mes-psdab7847  ppy-n2nme2n-emo-betadcph           7898  me2py-mepipe2-sem-nzdap7848  ppy-mepipe2-oem-nbetabnaphth       7899  amim-pymea-napo-bsdap7849  ppy-dimen-napo-betapy              7900  pippy-eta-fo-asppha7850  imhs-amn2-ocho-bnsdap              7901  me-n2nme2n-baeo-bhsdab7851  cl3pyme-diphmep-aco-zdapee         7902  pyr-24thiz-fo-zdab7852  imhs-edian2-fo-zdapee              7903  piraz-pnymea-no1-aspibua7853  chmhs-eta-fo-bphabs                7904  amim-24thizman2-chexo-7854  chmhs-mepazin-meo-zdap                   betainyl7855  thpym-din-5amo-psdab               7905  2py-eta-no1-psdap7856  bz-pyma2-5amo-zdapee               7906  menim-amo2-mes-betadcph7857  bimhs-pipmea-ocho-betainyl         7907  npip-eta-fo-mezphe7858  piraz-tridi-pyo-zdap               7908  piraz-dimen-pro-bhsdap7859  imhs-eta-ocho-bsdap                7909  2py-amn2-oem-bnsdap7860  bim-dimephmem-imo-betadcph         7910  dmbim-ams2-mes-bhsdap7861  imhs-tridi-aco-bphabs              7911  bim-din-ocho-csdap7912  n2py-trias-5amo-glyzdap             7964  bimhs-thizo-meo-psdab7913  me2py-n24thiman-meo-bhsdap          7965  2py-dimen-eoco-bnsdap7914  imhs-edian2-no2-betapy              7966  mepip-am3-oem-npsdap7915  amim-mepipe-napo-psdap              7967  pippy-tetradi-5amo-bhsdab7916  phpip-pazin-emo-aspibua             7968  bim-pazin-mes-betapy7917  thpym-amn2-oem-psdap                7969  hythpym-ams2-meo-bhsdap7918  bimhs-eta-oem-bhsdap                7970  npip-dimephmep-ocho-bnsdap7919  pippy-am3diaz-oem-mezphe            7971  bhs-m25thiz-fo-aval7920  bim-amn2-meo-bnsdap                 7972  pippy-trias-cpro-glupha7921  am2py-tridi-fo-psdab                7973  2py-eta-fo-aspibua7922  imhs-din-men-bhsdab                 7974  mam2py-2pazin-men-aspibua7923  imhs-amn2-eoco-bnsdap               7975  thpym-dimen-eoco-aspbzla7924  imhs-amo2-chexo-betapy              7976  bhs-m25oxman2-men-bhsdap7925  thpym-pipmeo-cnmo-aval              7977  bim-dimephmem-5pho-aspbzla7926  piraz-mea-5pho-bsdap                7978  pippy-25thiz-5amo-aspibua7927  pippy-eta-meo-csdap                 7979  morhs-propa2s-no2-bnsdap7928  piraz-mepazin-men-zdap              7980  thpym-mepipe-no1-psdab7929  bz-eta-cnmo-glyzdap                 7981  amthiaz-din-oem-bphabs7930  bhs-eta-fo-csdap                    7982  impy-pyma2-men-aspbzla7931  imhs-amn3-cpro-dfzdap               7983  z-eta-ocho-asppha7932  pippy-dimephmep-ocho-glyzdap        7984  bimhs-hexadi-eoco-mezphe7933  ppy-tetradi-mes-bnsdap              7985  bhs-amn2-pro-zdabs7934  tolhs-trias-fo-betapy               7986  bim-edian2-5pho-zdab7935  piraz-trias-cpeo-zdab               7987  pyraz-din-men-zdabs7936  am2py-tridi-chexo-zdab              7988  2py-tetras-4amo-zdabs7937  impy-25oxman2-ocho-betapy           7989  n2py-thizs-ocho-asppha7938  bz-pipmea-no2-asppha                7990  bhs-hexadi-oem-bhsdab7939  dmam-mea-mmen-bhsdab                7991  mam2py-pipmes-5pho-asppha7940  mam2py-pipmea-no1-psdab             7992  am-mea2s-no1-zdap7941  dmthpym-pipmea-oem-zdap             7993  bim-pipa-ocho-bhsdab7942  me-24thiz-nmo-csdap                 7994  bimhs-tridi-no2-aspbzla7943  cl3pyme-propn-cnmo-bphabs           7995  pippy-pipa-imo-bphabs7944  mam2py-tetradi-4amo-betainyl        7996  phpip-ms-meteto-aspibua7945  bim-edian2-no1-zdap                 7997  4pmhs-diphmem-eoco-zdap7946  dhim-edian2-5amo-zdapee             7998  bim-eta-no1-bnsdap7947  bim-dimephmep-fo-zdab               7999  mepip-n2o2n-fo-bnsdap7948  bz-dio-mes-oxal                     8000  ppy-24thiz-oem-betapy7949  piraz-pipa-no2-bsdap                8001  tolhs-dimephmem-ocho-dfzdap7950  me2py-diphmep-cnmo-csdap            8002  hythpym-2pazin-imo-bhsdab7951  mam2py-am2-sem-nbetameph            8003  thpym-pazin-eoco-psdap7952  gua-amo2-aco-psdab                  8004  thpym-mepipen2-oem-betadcph7953  dmthpym-dis-emo-thizzdap            8005  amim-tetras-imo-bphabs7954  4pmhs-mepipe-5pho-bnsdap            8006  am4py-m24thiz-mes-bhsdab7955  mam2py-m24thizman2-fo-bphabs        8007  bim-dimen-imo-osdap7956  im-mea2s-no1-betadcph               8008  phpip-din-imo-aspaba7957  moegua-dis-meteto-betapy            8009  thpym-mepipen2-5amo-psdap7958  hythpym-trias-mes-betapy            8010  me2py-tetradi-5pho-psdap7959  me2py-24thizman2-pyo-bhsdap         8011  thpym-pazin-fo-bhsdab7960  am2py-pymea-napo-mezphe             8012  mam2py-25oxman2-imo-betadcph7961  piraz-hexadi-paco-glyzdap           8013  am2py-m24thizman2-fo-bhsdap7962  me2py-tridi-fo-psdab                8014  4pmhs-24thiman2-oem-bhsdab7963  bim-amn2-eoco-bsdap                 8015  bhs-pazin-mes-betapy8016  bimhs-pazin-mes-betaet             8068  me2py-mepazin-men-aspbzla8017  thpym-pazin-meo-psdab              8069  imhs-ams2-no2-aspbzla8018  phhs-24thizman2-5pho-betadcph      8070  imhs-m24thizman2-eoco-dfzdap8019  thpym-edian2-meo-betapy            8071  dhim-dimen-no1-aspibua8020  mam2py-ams2-5amo-mezphe            8072  2py-edian2-hso-csdap8021  bim-edian2-ocho-bnsdap             8073  bhs-propa2s-oem-psdap8022  am2py-amn3-men-osdap               8074  2py-pentadi-meto-dfzdap8023  mepip-24oxman2-mes-tsdap           8075  dmthpym-thizn-napo-psdab8024  dmbim-amn3-4amo-mezphe             8076  dhim-m25thiz-chexo-bphabs8025  piraz-pentadi-emo-oxal             8077  bimhs-eta-eoco-aspbzla8026  bhs-edian2-5pho-betapy             8078  4pmhs-ams3-4pho-betainyl8027  bim-thizn-cno-betaet               8079  bimhs-pazin-no1-zdab8028  mam2py-dis-cnmo-bhsdab             8080  me2py-pymea-imo-psdapee8029  me2py-hexas-cno-bphabs             8081  bimhs-edian2-mes-zdab8030  dhim-pazin-no1-bphabs              8082  bimhs-mepipe-baeo-aspbzla8031  chhs-thizn-baeo-bhsdab             8083  imhs-amn2-no2-psdap8032  npip-amn3-peo-bsdap                8084  dhim-25oxman2-oem-zdab8033  impy-edian2-imo-aspibua            8085  mam2py-eta-pro-zdabs8034  emnim-pipmeo-no1-tsdap             8086  prhs-tetradi-5amo-osdap8035  2py-m25thiman2-ocho-aspibua        8087  ppy-tridi-napo-dfzdap8036  2py-24thiz-fo-betadcph             8088  2py-eta-oem-zdap8037  pyr-24thiman2-imo-mezphe           8089  hythpym-din-cno-bsdap8038  dmthpym-n2o2n-paco-zdap            8090  amim-pipmea-men-aspaba8039  impy-edia2-oem-nzdap               8091  ppy-pipmea-5pho-betapy8040  pippy-m25thiz-hso-zorn             8092  hythpym-tridi-5amo-aspbzla8041  piraz-24thizman2-emo-asppha        8093  thpym-pymea-oem-asppha8042  amim-24thiz-no2-asppha             8094  deam-24thizman2-emo-thizzdap8043  impy-thizo-cno-psdap               8095  amthiaz-pipmea-chexo-bnsdap8044  chhs-mepipen2-mes-zdap             8096  dmthpym-pyma2-chexo-bhsdap8045  nmhs-pazin-chexo-zdab              8097  ppy-n2nme2n-oem-dfzdap8046  me-m25thiz-mommo-mezphe            8098  thpym-mepipe2-sem-npsdap8047  cl3pyme-pipmes-meo-psdapee         8099  am4py-am2-oem-nbetabnaphth8048  mam2py-propn-no1-mezphe            8100  bim-am3-sem-nbetabnaphth8049  chhs-din-meo-mezphe                8101  amthiaz-dimephmep-cpeo-8050  npip-25oxman2-pro-zdabs                  aspbzla8051  me-dis-4pho-bnsdap                 8102  bim-eta-eoco-betapy8052  imhs-amn3-5amo-betaet              8103  me2py-dimephmep-ocho-bsdap8053  dhim-24thiz-cnmo-aspibua           8104  imhs-hexas-nmo-aspbzla8054  2py-amn2-no1-psdab                 8105  deam-m24oxman2-chexo-bphabs8055  bimhs-mepazin-pyo-betadcph         8106  tolhs-eta-chexo-aspibua8056  amthiaz-dimen-nmo-psdap            8107  am-tetradi-mes-psdab8057  bhs-pentas-baeo-glyzdap            8108  gua-dimephmem-cpeo-psdab8058  mam2py-n24thiman-5pho-bhsdab       8109  mam2py-diphmep-no1-zdabs8059  imhs-edian2-eoco-betapy            8110  pyraz-din-emo-betadcph8060  2py-eta-eoco-betapy                8111  dmthpym-dis-meo-csdap8061  amim-pyma2-napo-zdab               8112  amim-thizn-pro-bnsdap8062  thpym-pymea-eoco-betadcph          8113  impy-mea2s-men-bphabs8063  emnim-pyma2-oem-aspibua            8114  me2py-25oxman2-baeo-bhsdab8064  bimhs-mepipen2-no2-asppha          8115  ibhs-diphmem-meo-thizzdap8065  mepip-thizn-meo-betadcph           8116  imhs-pazin-5pho-bnsdap8066  pyr-mepipe-mes-aspibua             8117  edothpym-pipmea-meo-mezphe8067  am2py-tetradi-no2-thizzdap         8118  me2py-n24thiman-eoco-csdap8119  2py-diphmep-emo-tsdap               8171  menim-m24thiz-mes-aspibua8120  pippy-diphmep-imo-mezphe            8172  hythpym-eta-napo-glyzdap8121  amim-hexadi-emo-aspibua             8173  dhim-diphmem-meo-psdap8122  dmthpym-diphmem-5amo-psdapee        8174  thpym-amn2-fo-psdab8123  moegua-24thizman2-napo-zdabs        8175  am2py-amn3-chexo-dfzdap8124  pippy-pazi2n-men-zorn               8176  imhs-edian2-5pho-bnsdap8125  imhs-ams2-ocho-oxal                 8177  n2py-24oxman2-no1-bnsdap8126  bimhs-pipmea-oeto-glupha            8178  im-mepazin-pyo-bhsdap8127  2py-edian2-ocho-bnsdap              8179  dhim-tetradi-oem-mezphe8128  thpym-m25thiman2-mecpo-zdab         8180  2pmhs-mepipe2-oem-nzdab8129  thpym-amn2-ocho-bnsdap              8181  piraz-25thizman2-mecpo-csdap8130  dhim-pyma2-no1-osdap                8182  2pmhs-din-5pho-betapy8131  bhs-edian2-meo-bsdap                8183  2py-amn2-no2-bhsdap8132  dmthpym-pazin-no2-psdab             8184  impy-propn-meo-zdab8133  pippy-am3-oem-nzdap                 8185  moegua-am2-sem-nzdab8134  bimhs-24thiz-no2-zdapee             8186  2py-amn2-men-osdap8135  thpym-pazin-no1-zdap                8187  pippy-trias-eoco-tsdap8136  mam2py-amo2-oeto-zdabs              8188  dpam-mepipe2-oem-nzdap8137  nmor-3diaz-ocho-asppha              8189  thpym-pymea-pro-bnsdap8138  hythpym-propn-emo-bhsdab            8190  amim-3diaz-meo-dfzdap8139  ibhs-m25thiz-cpro-bhsdab            8191  bim-amn2-no1-bhsdap8140  bimhs-thizn-cpeo-dfzdap             8192  dhim-dimephmep-napo-betainyl8141  thpym-eta-mes-bnsdap                8193  bimhs-pipa-mecpo-zdap8142  me2py-tridi-men-bhsdap              8194  prhs-mepipe-meo-betapy8143  bim-pymea-men-bhsdab                8195  pippy-diphmep-no1-mezphe8144  bim-24thiz-ocho-aspbzla             8196  bim-edian2-eoco-psdap8145  dhim-mepazin-fo-psdap               8197  bhs-dimen-chexo-betapy8146  nim-dis-emo-mezphe                  8198  amim-pnymea-no2-dfzdap8147  impy-dimephmep-5pho-betainyl        8199  pippy-3pazin-eoco-mezphe8148  me2py-diphmep-5pho-mezphe           8200  nmhs-dis-no1-zdap8149  nim-pymea-cpro-csdap                8201  dmbim-pyma2-pro-ibsdap8150  amim-dimen-meto-zdab                8202  thpym-eta-mes-bhsdap8151  am2py-pnymea-emo-psdab              8203  prhs-am2-oem-nzdab8152  pippy-tridi-fo-psdab                8204  deam-amn3-5amo-aspaba8153  am2py-thizs-napo-bphabs             8205  impy-dimephmep-no1-betadcph8154  bim-pazin-meo-psdap                 8206  bhs-pymea-no1-zdabs8155  piraz-mepipen2-mmen-thizzdap        8207  z-amn3-napo-glyzdap8156  imhs-pazin-mes-bhsdab               8208  amim-25oxman2-men-zdab8157  im-amo2-ocho-psdap                  8209  bim-diphmep-meo-betainyl8158  ec-ams3-meo-glubzla                 8210  piraz-24thizman2-4amo-bnsdap8159  bim-dimephmep-emo-betapy            8211  4pmhs-propn-imo-aspibua8160  bhs-24thizman2-ocho-dfzdap          8212  nim-din-chexo-psdab8161  nmhs-24thizman2-oem-bsdap           8213  hythpym-thizn-emo-bsdap8162  tolhs-dimen-emo-bhsdab              8214  pyrhs-trias-hso-psdab8163  pippy-24thizman2-meo-aspaba         8215  ibhs-dimen-eoco-betapy8164  bhs-edian2-5amo-ppsdap              8216  am2py-m24thizman2-meo-mezphe8165  2py-amo2-meo-bnsdap                 8217  dhim-dimephmep-no1-bphabs8166  2pmhs-m25thiz-ocho-psdab            8218  am2py-24thizman2-no1-aval8167  imhs-trias-eoco-mezphe              8219  mepip-trias-napo-bnsdap8168  nmhs-m25thiz-mommo-aspibua          8220  nmhs-dimephmep-chexo-zdap8169  bhs-mepipe-eoco-psdap               8221  fthpym-mepipe-hso-aspbzla8170  pippy-mea2s-ocho-zdab               8222  imhs-mepipe-mes-glyzdap8223  bhs-dipch-5amo-betainyl            8274  amim-ms-5pho-psdap8224  dhim-pazin-eoco-bphabs             8275  hythpym-pnymea-ocho-bphabs8225  dmbim-dimephmep-no2-asppha         8276  2py-24thiz-oem-zorn8226  nmor-ams2-pro-betadcph             8277  2py-pipa-chexo-mezphe8227  nim-3diaz-5amo-ppsdap              8278  ppy-dimephmem-fo-betainyl8228  impy-eta-meo-psdab                 8279  mam2py-mepipe-napo-betadcph8229  pippy-dimen-mmen-zdabs             8280  hythpym-edian2-fo-betapy8230  2py-pnymea-emo-bhsdap              8281  piraz-propa2s-fo-bhsdab8231  impy-edian2-fo-psdap               8282  pyrhs-tridi-nmo-betainyl8232  bim-diphmep-imo-mezphe             8283  piraz-diphmep-5amo-csdap8233  hythpym-thizn-emo-psdap            8284  ppy-pipmea-ocho-bphabs8234  phhs-din-fo-bhsdab                 8285  2pmhs-thizn-napo-asppha8235  dmbim-edian2-5pho-glupha           8286  impy-25thiman2-chexo-zdap8236  prhs-am2-oem-nbetabnaphth          8287  bhs-mepipe-eoco-zdap8237  bhs-mepipe2-oem-nbetameph          8288  thpym-25oxman2-oem-zdap8238  nmor-diphmep-oem-aspbzla           8289  2py-pyma2-napo-psdab8239  2py-edian2-oem-psdap               8290  thpym-amn2-mes-bsdap8240  pyrhs-edian2-baeo-bphabs           8291  mam2py-25oxman2-5amo-betaet8241  2py-dimen-hso-oxal                 8292  dmbim-am2-sem-nbeta34dimeoph8242  2py-mepipen2-5amo-psdab            8293  pippy-pipmes-meteto-zdabs8243  mepip-mepipen2-5amo-thizzdap       8294  hythpym-pentadi-no1-zdabs8244  thpym-m24thiz-chexo-bnsdap         8295  mam2py-butn-napo-thizzdap8245  bhs-indan2-imo-bsdap               8296  thpym-pipa-napo-betadcph8246  tolhs-mepipen2-oeto-aspibua        8297  pippy-ams2-nmo-betapy8247  bimhs-eta-no2-zorn                 8298  am4py-diphmem-oem-glyzdap8248  thpym-mepipe-eoco-bnsdap           8299  bimhs-mepipe2-oem-nbetab8249  bhs-eta-no1-zdab                         naphth8250  edothpym-24thizman2-men-           8300  thpym-2pazin-peo-glyzdap
  betapy                             8301  bhs-eta-eoco-psdap8251  dmbim-pnymea-5amo-aspaba           8302  2pmhs-diphmem-oem-zdap8252  impy-thizo-fo-betaet               8303  pippy-pnymea-no1-csdap8253  imhs-mepipe-eoco-zdab              8304  bim-edia2-sem-nbetameph8254  mepip-amo2-pyo-psdap               8305  mam2py-25thizman2-fo-mezphe8255  chhs-m25thiz-chexo-bhsdab          8306  imhs-trias-pheo-zdabs8256  hythpym-m25thiz-no2-dfzdap         8307  pyrhs-m25thizman2-napo-8257  nim-ams2-5pho-aspibua                    glyzdap8258  am4py-pnymea-oem-zdap              8308  hythpym-24thizman2-no1-bhsdab
8259  gua-pipa-men-bphabs                8309  imhs-ams2-pyo-psdab8260  bimhs-25oxman2-oem-mezphe          8310  phpip-amo2-oem-ppsdap8261  2py-amn2-eoco-bsdap                8311  bhs-24thizman2-men-betapy8262  ibhs-pymea-cpeo-zdapee             8312  impy-m25thiz-pyo-betapy8263  z-amn3-pheo-aval                   8313  impy-m25thiz-nmo-glyzdap8264  bz-dimephmem-cnmo-zorn             8314  hythpym-din-cpeo-aspibua8265  mam2py-thizn-5pho-bsdap            8315  thpym-pymea-no1-zdap8266  piraz-ms-oeto-bsdap                8316  nmor-3diaz-pyo-psdap8267  bimhs-24thizman2-imo-aspibua       8317  me-thizn-men-bphabs8268  fthpym-propa2s-imo-bhsdab          8318  bim-eta-no1-psdab8269  thpym-am3diaz-napo-aspbzla         8319  bim-mepipen2-imo-aspbzla8270  hythpym-dis-aco-betadcph           8320  bhs-mepipe-no2-bnsdap8271  bhs-amo2-meo-betadcph              8321  me2py-m25thizman2-napo-ppsdap8272  bimhs-am3-oem-nzdab                8322  pippy-propa2s-mecpo-bhsdab8273  hythpym-pipmea-napo-zdabs          8323  imhs-25oxman2-imo-mezphe8324  bimhs-pipmes-5pho-mezphe           8376  me2py-pnymea-pro-bhsdap8325  bim-25thizman2-napo-betainyl       8377  n2py-m24thizman2-emo-psdab8326  moegua-trias-imo-betadcph          8378  impy-tetradi-pyo-betapy8327  am2py-pipmea-eoco-dfzdap           8379  piraz-edian2-napo-betapy8328  mam2py-ams2-fo-glyzdap             8380  thpym-edian2-no2-zdap8329  prhs-din-meo-bphabs                8381  prhs-diphmem-baeo-bsdap8330  pippy-pipa-oem-betadcph            8382  bim-pyma2-5amo-bnsdap8331  am2py-mepazin-ocho-bsdap           8383  nim-tetradi-chexo-aspbzla8332  amim-mepipen2-eoco-mezphe          8384  amthiaz-pazin-5amo-zdap8333  thpym-mea-fo-asppha                8385  amim-pipmea-meo-mezphe8334  ec-amn3-chexo-aspaba               8386  impy-25oxman2-4amo-betadcph8335  mam2py-mea-chexo-zdap              8387  amim-tetradi-imo-aspibua8336  amim-amn2-no1-dfzdap               8388  2py-amn2-mes-psdab8337  hythpym-25thizman2-no1-bhsdab      8389  deam-dio-cnmo-dfzdap8338  bimhs-dimen-emo-glyzdap            8390  2py-hexadi-5pho-aspbzla8339  mam2py-m24thizman2-5pho-bsdap      8391  bhs-mepipe-meo-betapy8340  hythpym-dich-no1-betainyl          8392  amim-props-pheo-bsdap8341  amim-tetras-oem-zdabs              8393  me2py-24thiz-paco-betainyl8342  prhs-diphmep-cno-mezphe            8394  impy-tetradi-no1-psdab8343  2py-dimephmem-fo-glupha            8395  edothpym-amn3-cpro-bhsdab8344  morhs-mepipe-ocho-bhsdab           8396  bhs-mepipe-oem-bnsdap8345  pippy-m25thiz-fo-bsdap             8397  piraz-m24thiman2-no1-bhsdab8346  impy-25thiz-fo-aval                8398  ppy-pymea-ocho-csdap8347  impy-indan2-mecpo-betapy           8399  imhs-m25thiz-meto-ppsdap8348  2py-dimen-emo-betaet               8400  phpip-amn2-fo-glyzdap8349  thpym-pipa-no1-bsdap               8401  am2py-25oxman2-no1-bhsdab8350  am2py-mepipe-meteto-zdabs          8402  me2py-dimephmem-eoco-asppha8351  dmam-diphmem-eoco-aspbzla          8403  n2py-edian2-meo-betainyl8352  thpym-tetradi-meo-csdap            8404  me-trias-no2-mezphe8353  2py-eta-mes-betapy                 8405  npip-2pazin-emo-bsdap8354  am2py-pipmea-baeo-betaet           8406  piraz-mepipen2-emo-psdapee8355  bim-m25oxman2-oeto-zdap            8407  cl3pyme-pipmea-eoco-bphabs8356  pippy-amn2-meo-dfzdap              8408  am4py-trias-no2-ibsdap8357  dmthpym-tridi-fo-dfzdap            8409  impy-m25thiz-meo-zlys8358  gua-mepazin-meto-csdap             8410  piraz-dimen-emo-zdab8359  ppy-dimephmem-emo-psdapee          8411  2pmhs-tetradi-5amo-glyzdap8360  mam2py-eta-meo-osdap               8412  am2py-dimephmem-ocho-bhsdap8361  pyraz-eta-emo-bhsdab               8413  phhs-tridi-5amo-betadcph8362  me2py-ms-5amo-aspibua              8414  2py-24thizman2-men-bnsdap8363  mepip-tetradi-cnmo-psdab           8415  am2py-pentas-pheo-tsdap8364  z-25thiz-5amo-zlys                 8416  impy-pipmeo-mes-zdabs8365  amim-am3-oem-nbetapy               8417  me-m25oxman2-5pho-dfzdap8366  nmor-m24thiman2-fo-mezphe          8418  piraz-diphmep-pro-bsdap8367  fthpym-mea2s-chexo-betadcph        8419  dhim-dis-chexo-betadcph8368  am2py-24thiz-cnmo-dfzdap           8420  imhs-3pazin-no1-aspibua8369  moegua-dimen-5pho-osdap            8421  dmbim-pazin-imo-aval8370  morhs-dipch-emo-zdap               8422  2py-pnymea-mmen-asppha8371  amim-edian2-peo-betainyl           8423  bhs-mepipe-meo-bnsdap8372  2py-tetradi-chexo-betapy           8424  hythpym-dimephmem-no2-8373  imhs-am3diaz-oem-csdap                   betainyl8374  moegua-mepipen2-mecpo-bsdap        8425  ppy-24thiz-men-betainyl8375  z-diphmep-no2-zdab                 8426  bhs-amn3-ocho-bsdap8427  menim-25oxman2-daco-zdab            8478  gua-thizn-fo-tsdap8428  me2py-dis-aco-bhsdab                8479  mam2py-m24thizman2-5pho-zdab8429  imhs-dis-emo-psdap                  8480  piraz-m24thiman2-no2-zdabs8430  4pmhs-edia2-sem-nbeta34             8481  dhim-edian2-chexo-bhsdab
  dimeoph                             8482  thpym-mea2s-no2-bhsdap8431  bim-edian2-no2-psdap                8483  dhim-diphmep-pheo-csdap8432  thpym-pipmea-no2-aspibua            8484  me2py-mepipen2-no2-asppha8433  bhs-am2-oem-nbetameph               8485  amim-am3-sem-nbetabnaphth8434  amim-mepipe2-sem-nbetameph          8486  piraz-tridi-imo-zdabs8435  me2py-thizs-paco-bhsdap             8487  fthpym-amo2-5pho-glyzdap8436  ec-am2-sem-nbeta34dimeoph           8488  pippy-amn2-napo-zdap8437  mam2py-din-no1-glyzdap              8489  piraz-amn3-no1-betadcph8438  am2py-dipch-mes-zdap                8490  z-tridi-nmo-mezphe8439  piraz-dimephmep-no1-aspibua         8491  bimhs-pipmea-5amo-bphabs8440  hythpym-dio-mes-osdap               8492  am4py-edia2-oem-nzdab8441  imhs-thizo-pro-glyzdap              8493  emnim-m25thiz-meto-bhsdab8442  bimhs-pipa-hso-aspbzla              8494  bimhs-pyma2-cno-mezphe8443  amim-pipa-5pho-zdabs                8495  pippy-dimephmep-men-bsdap8444  me2py-mepazin-men-zdabs             8496  hythpym-am3-sem-nbetabnaphth8445  imhs-amn2-mes-betainyl              8497  piraz-n2nme2n-oem-zdap8446  im-eta-mecpo-zdab                   8498  mam2py-dis-5amo-betapy8447  imhs-25thiman2-no2-aspbzla          8499  hythpym-dimephmem-chexo-8448  bz-25thiz-cpro-aspaba                     dfzdap8449  bhs-diphmem-no2-psdap               8500  mam2py-ams2-daco-osdap8450  bhs-m25thiz-5amo-bsdap              8501  pyraz-edian2-ocho-psdab8451  piraz-tetradi-5amo-bphabs           8502  am2py-m24thizman2-meto-aval8452  thpym-edian2-oem-psdap              8503  hythpym-thizn-emo-bhsdap8453  moegua-ams2-nmo-psdab               8504  moegua-ams2-no2-zdab8454  moegua-mea2s-chexo-bhsdab           8505  moegua-ams2-imo-aspbzla8455  hythpym-eta-men-betainyl            8506  bim-dimephmem-meo-betadcph8456  nim-25thiz-4amo-betapy              8507  am2py-m24thizman2-aco-bnsdap8457  mam2py-25thiman2-eoco-aspibua       8508  mepip-tridi-men-bnsdap8458  chmhs-thizn-eoco-betainyl           8509  bhs-pipa-no1-aspibua8459  z-m24thiz-5pho-csdap                8510  ibhs-dimephmep-men-bnsdap8460  pippy-pnymea-imo-bnsdap             8511  piraz-dis-chexo-bsdap8461  bhs-edian2-no1-zdab                 8512  edothpym-amn2-emo-zdapee8462  z-ams2-ocho-zdabs                   8513  mepip-24oxman2-fo-aval8463  nmor-amo3-5amo-mezphe               8514  impy-tetradi-5amo-glyzdap8464  ppy-thizn-no2-csdap                 8515  2py-mepipen2-eoco-zdap8465  hythpym-dipch-chexo-csdap           8516  am-diphmep-no2-betadcph8466  pyraz-pipmea-oem-bhsdab             8517  bim-pnymea-hso-mezphe8467  bhs-pazin-mes-bsdap                 8518  piraz-24thiz-cno-glyzdap8468  me-amn3-pro-dfzdap                  8519  amim-2pazin-napo-tsdap8469  piraz-24thizman2-ocho-glyzdap       8520  bimhs-n24thiman-mommo-bnsdap8470  ppy-amn3-eoco-betapy                8521  am-amn3-5pho-aspibua8471  amim-diphmep-nmo-betapy             8522  bim-eta-chexo-betapy8472  me2py-m25thiz-4pho-zdap             8523  dmam-pazin-5amo-zdap8473  me2py-pymea-napo-aspaba             8524  imhs-m24thizman2-napo-bnsdap8474  emnim-edia2-sem-nbetabnaphth        8525  thpym-ams2-eoco-psdap8475  pyraz-mepipen2-napo-zdabs           8526  chhs-24thizman2-imo-betadcph8476  chhs-edian2-no1-dfzdap              8527  pippy-diphmep-meo-glyzdap8477  deam-din-no2-ibsdap                 8528  am4py-am2-sem-nzdap8529  bhs-amn2-5pho-psdap                 8581  dhim-pipmea-5amo-ppsdap8530  pippy-dimephmep-5amo-bnsdap         8582  impy-amo2-cnmo-zdabs8531  menim-indan2-no1-tsdap              8583  pyr-amo3-ocho-aspaba8532  me2py-tridi-meo-bphabs              8584  bimhs-edian2-napo-bphabs8533  cl3pyme-ams2-4pho-psdap             8585  pippy-mepipen2-no2-glubzla8534  imhs-amn2-5pho-betapy               8586  pippy-dich-mommo-aspibua8535  pippy-diaz-fo-psdapee               8587  thpym-din-no2-aspibua8536  bhs-mepipe2-oem-nbetabnaphth        8588  bhs-pazin-meo-psdap8537  hythpym-mepipen2-no1-betapy         8589  npip-amn3-mommo-csdap8538  2py-edian2-no2-betapy               8590  n2py-dimephmem-meo-bhsdap8539  2py-diphmep-imo-glubzla             8591  bim-dis-oem-betainyl8540  me-mepipe2-oem-nbeta34dimeoph       8592  2py-pipa-4amo-psdap8541  edothpym-eta-oeto-bsdap             8593  n2py-thizs-ocho-bphabs8542  pyr-diphmep-fo-bnsdap               8594  imhs-eta-napo-psdab8543  pippy-dimen-cnmo-aspbzla            8595  im-pnymea-emo-betainyl8544  hythpym-pazi2n-ocho-betainyl        8596  hythpym-dimen-no1-asppha8545  thpym-dis-napo-psdab                8597  4pmhs-25thiz-oem-betadcph8546  chmhs-2pazin-men-dfzdap             8598  2py-din-pro-oxal8547  bim-edian2-ocho-bhsdap              8599  bim-edian2-no2-zdap8548  pippy-pipa-5amo-betadcph            8600  gua-mea2s-fo-zdap8549  bzl-n2nme2n-men-psdab               8601  thpym-pipmea-chexo-csdap8550  2py-amn2-napo-psdab                 8602  bhs-n2o2n-mommo-bsdap8551  bimhs-mepipen2-mes-mezphe           8603  phhs-diphmep-5amo-psdab8552  me2py-diphmep-mes-dfzdap            8604  ppy-thizn-imo-csdap8553  morhs-ams2-nmo-glubzla              8605  4pmhs-diaz-imo-psdap8554  edothpym-hexadi-fo-zdabs            8606  nmhs-am2-oem-npsdap8555  thpym-pazin-no2-zdap                8607  tolhs-mea-fo-csdap8556  bimhs-pentas-5amo-glyzdap           8608  impy-pipmeo-no1-ppsdap8557  am2py-tridi-cpro-csdap              8609  4pmhs-trias-imo-betadcph8558  bimhs-m25thiz-mes-aspaba            8610  thpym-pazin-5pho-bhsdap8559  impy-24thizman2-no2-betainyl        8611  mam2py-din-meo-mezphe8560  4pmhs-m25thiman2-imo-zlys           8612  bim-eta-no2-bhsdap8561  dmbim-eta2s-meteto-aspibua          8613  bhs-25thiz-fo-bphabs8562  me2py-m24thizman2-meteto-zorn       8614  2py-amo2-mecpo-asppha8563  bz-thizn-cno-psdab                  8615  hythpym-dis-no1-bphabs8564  edothpym-diaz-emo-bnsdap            8616  bim-pipa-meto-ppsdap8565  amim-amn3-fo-csdap                  8617  me2py-2pazin-5pho-betapy8566  thpym-amn2-5pho-psdap               8618  nmhs-25oxman2-men-bnsdap8567  me2py-dimephmep-imo-ppsdap          8619  tolhs-diphmep-daco-betadcph8568  me2py-m25thiz-daco-asppha           8620  pippy-pentas-fo-mezphe8569  amim-dimen-imo-aspibua              8621  pyrhs-tetradi-cno-mezphe8570  mcrhs-dimephmem-fo-mezphe           8622  z-mepipe2-oem-nbeta34dimeoph8571  thpym-pazin-5pho-zdab               8623  mepip-ams3-mes-glupha8572  2py-mepipen2-5pho-thizzdap          8624  4pmhs-tridi-5pho-bhsdab8573  bimhs-amo2-5amo-asppha              8625  bhs-mepipe-eoco-bnsdap8574  nmor-am3-sem-nbeta34dimeoph         8626  am-edian2-fo-bphabs8575  bim-dimephmep-meto-aspbzla          8627  phhs-pyma2-napo-bnsdap8576  bhs-diphmem-oem-aspbzla             8628  mepip-dis-nmo-aspbzla8577  me2py-pazin-nmo-psdab               8629  2py-mepipe-ocho-bhsdap8578  me2py-am3-sem-nbetapy               8630  impy-edia2-sem-nbeta34dimeoph8579  hythpym-24thizman2-napo-aval        8631  ec-amn3-men-dfzdap8580  2py-eta-eoco-zdap                   8632  im-thizn-baeo-psdab8633  bhs-mepipe-5pho-zdap                  8685  bimhs-thizn-mmen-asppha8634  2py-25oxman2-meo-psdap                8686  bhs-mepipen2-no2-betainyl8635  chmhs-din-chexo-asppha                8687  2pmhs-thizn-5amo-zlys8636  bim-amn2-mes-zdap                     8688  piraz-ams2-mmen-psdab8637  bhs-tetradi-men-csdap                 8689  impy-dio-no1-betainyl8638  bim-24thizman2-oem-betapy             8690  imhs-eta-meo-bsdap8639  amim-mepipen2-eoco-aspibua            8691  imhs-amn2-no2-bsdap8640  imhs-m25thiz-no2-aspibua              8692  pippy-pyma2-5amo-dfzdap8641  chmhs-m25thiz-chexo-zdabs             8693  bz-thizn-no1-zdabs8642  pyr-am2-oem-nbeta34dimeoph            8694  2pmhs-thizn-no1-ibsdap8643  impy-24thiman2-napo-betadcph          8695  thpym-tridi-imo-zdap8644  cl3pyme-dich-meo-psdap                8696  am4py-m25thiz-cnmo-csdap8645  ibhs-diphmem-no2-betainyl             8697  imhs-m25thizman2-ocho-csdap8646  mepip-24thizman2-mes-ibsdap           8698  bzl-24oxman2-meo-zdap8647  z-24thizman2-mes-bsdap                8699  mam2py-edian2-pro-bphabs8648  tolhs-tetras-mommo-psdab              8700  2py-mepipe-no1-bhsdap8649  amim-mea-pyo-bhsdap                   8701  amim-amn3-paco-glyzdap8650  bhs-amo3-5amo-glupha                  8702  morhs-24thiz-5pho-psdap8651  bim-dimen-meteto-zdapee               8703  dpam-dis-emo-betainyl8652  me2py-mepipe-daco-bhsdap              8704  imhs-pazin-eoco-zdab8653  bimhs-dimephmem-5pho-bhsdab           8705  ibhs-n24thiman-imo-dfzdap8654  bim-25thizman2-nmo-psdab              8706  pippy-pipa-chexo-aspibua8655  bimhs-mea-ocho-bsdap                  8707  am2py-diphmem-mommo-bhsdab8656  am2py-tridi-imo-asppha                8708  imhs-pnymea-pheo-aspbzla8657  pippy-mepipe2-sem-nbetapy             8709  bim-pazin-oem-bsdap8658  emnim-diphmep-imo-bsdap               8710  morhs-pymea-mes-betainyl8659  piraz-m25thiz-oem-bphabs              8711  thpym-pentas-ocho-betadcph8660  amim-am2-sem-nzdab                    8712  thpym-trias-men-bhsdap8661  piraz-diphmem-eoco-zorn               8713  2py-edian2-oem-bhsdap8662  bim-edian2-no2-bnsdap                 8714  chhs-dimen-nmo-betapy8663  bim-24thizman2-imo-betapy             8715  imhs-ams2-oem-betainyl8664  am2py-amn3-no2-bhsdap                 8716  bhs-m25thiz-baeo-dfzdap8665  amim-dich-eoco-bsdap                  8717  am-amn3-mecpo-betapy8666  bzl-am2-sem-npsdap                    8718  menim-dio-men-bphabs8667  impy-m25thiz-daco-csdap               8719  bhs-m24thiman2-baeo-zdab8668  z-24thiman-mes-mezphe                 8720  imhs-m24thiman2-pyo-betapy8669  imhs-dimephmem-pheo-zorn              8721  pyraz-pyma2-imo-dfzdap8670  mim-amn2-pheo-bhsdap                  8722  nmhs-mea-meto-psdab8671  bhs-diphmep-emo-bhsdab                8723  am4py-25oxman2-no1-aspibua8672  nmor-pipmea-chexo-betainyl            8724  imhs-amn3-ocho-zdap8673  bhs-pazin-meo-bhsdap                  8725  ibhs-diphmep-meo-glyzdap8674  phpip-pipmea-imo-aspbzla              8726  piraz-ams2-no1-aspibua8675  dhim-din-chexo-aspibua                8727  gua-edian2-cpro-aspibua8676  pippy-amn3-oem-zdabs                  8728  am-trias-5amo-ibsdap8677  bim-tridi-chexo-aspibua               8729  hythpym-mepazin-imo-bsdap8678  thpym-pazin-5amo-aspbzla              8730  am4py-edia2-oem-npsdap8679  me2py-24oxman2-fo-mezphe              8731  bhs-tetras-men-bhsdab8680  me2py-diaz-5pho-zdap                  8732  dhim-mepipen2-cpro-glubzla8681  bimhs-dimen-chexo-mezphe              8733  bim-pnymea-chexo-betapy8682  phpip-pymea-men-bhsdap                8734  pyraz-pnymea-5pho-dfzdap8683  bhs-ms-4amo-mezphe                    8735  phpip-pazin-pyo-csdap8684  dhim-pipa-napo-betadcph               8736  moegua-amo2-emo-bsdap8737  imhs-edian2-no1-zdap                  8789  emnim-pazin-daco-tsdap8738  chmhs-tetras-no1-zdap                 8790  impy-am3-sem-nbeta34dimeoph8739  thpym-amn2-ocho-betapy                8791  moegua-edia2-sem-nbetameph8740  npip-eta-eoco-csdap                   8792  am2py-tetradi-eoco-oxal8741  amthiaz-mepipe-5pho-psdab             8793  pyrhs-amn2-mes-bphabs8742  pyrhs-amn3-eoco-betadcph              8794  bim-hexadi-no1-zdab8743  mepip-diphmep-5amo-zdab               8795  pyraz-ams2-no2-bphabs8744  amim-dimephmep-mes-zlys               8796  bim-m25thizman2-emo-csdap8745  bim-thizn-emo-bnsdap                  8797  am2py-dimephmem-meo-aspibua8746  imhs-ams2-meo-bnsdap                  8798  bimhs-dimephmep-men-bphabs8747  am-din-no2-bhsdap                     8799  bhs-amn3-emo-dfzdap8748  imhs-eta-mes-bhsdap                   8800  thpym-diphmem-meteto-mezphe8749  impy-am2-oem-nzdab                    8801  2py-edian2-men-glupha8750  thpym-ams2-mecpo-psdapee              8802  dpam-m24thizman2-oem-glyzdap8751  2py-24thiz-napo-glyzdap               8803  impy-thizs-eoco-betadcph8752  bzl-25oxman2-mes-bnsdap               8804  pippy-pipa-5amo-bhsdab8753  edothpym-mepazin-aco-aspbzla          8805  dhim-mepazin-oem-csdap8754  thpym-eta-no1-zdap                    8806  2py-amn2-5pho-bhsdap8755  bz-tetras-pheo-bhsdap                 8807  bz-diphmem-mommo-betainyl8756  me2py-thizn-eoco-bsdap                8808  impy-mepipe-oem-betainyl8757  bim-mepazin-emo-aspibua               8809  chmhs-24thiz-meo-aspibua8758  gua-pipa-meto-csdap                   8810  bhs-25thiz-cno-dfzdap8759  ppy-am3diaz-emo-psdab                 8811  nmor-diphmem-napo-psdapee8760  am2py-din-eoco-aval                   8812  me2py-24thiz-men-betainyl8761  am4py-pyma2-fo-csdap                  8813  me2py-amn2-5pho-tsdap8762  dmthpym-24thiman-emo-betainyl         8814  am2py-diphmem-daco-zdab8763  dmam-mepipen2-no2-zdabs               8815  dhim-mepipe2-oem-nbeta34-8764  bimhs-m24thizman2-no1-bhsdab                dimeoph8765  me2py-24thiz-emo-zdab                 8816  imhs-tridi-men-dfzdap8766  imhs-mepipe-5pho-zdab                 8817  4pmhs-pipa-napo-dfzdap8767  moegua-mea-ocho-zdab                  8818  bhs-din-pyo-mezphe8768  piraz-diphmem-emo-zlys                8819  imhs-pazi2n-ocho-glyzdap8769  prhs-diphmem-no2-aspibua              8820  bhs-25oxman2-chexo-aval8770  imhs-pipmea-mes-bhsdap                8821  piraz-pymea-emo-dfzdap8771  piraz-pazin-napo-psdab                8822  phpip-m25thiz-napo-zdap8772  am2py-pipa-4amo-ibsdap                8823  dhim-dimen-ocho-bhsdab8773  edothpym-dio-imo-bhsdap               8824  am2py-trias-emo-zdap8774  thpym-pymea-emo-mezphe                8825  bimhs-diphmem-emo-betapy8775  thpym-eta-mes-zdap                    8826  dmbim-mepipe-oem-betainyl8776  thpym-2pazin-imo-zdabs                8827  mepip-dimephmep-cpeo-bhsdab8777  piraz-dimephmep-meto-csdap            8828  amim-m25oxman2-5pho-betapy8778  am2py-24thizman2-5pho-psdap           8829  moegua-propa2s-5amo-aspibua8779  chmhs-pipa-no2-ppsdap                 8830  bhs-24thizman2-napo-oxal8780  amthiaz-din-emo-csdap                 8831  2py-mepipe-5pho-betapy8781  bim-dis-mes-zdap                      8832  z-amn3-emo-asppha8782  pyrhs-pipmea-mes-ppsdap               8833  thpym-tetras-mes-dfzdap8783  dhim-diphmep-oem-bnsdap               8834  imhs-diphmem-5amo-zdabs8784  nmhs-mepipe-nmo-asppha                8835  pippy-amn2-napo-zdap8785  mam2py-eta-5amo-bphabs                8836  bhs-indan2-no2-psdap8786  edothpym-m25thiz-oem-psdap            8837  thpym-m24thiman2-cpro-dfzdap8787  pippy-dimephmem-imo-psdapee           8838  2py-pazin-5pho-bhsdap8788  piraz-dimephmep-5pho-zdabs            8839  pippy-amo2-fo-asppha8840  n2py-pipmea-napo-zdab              8891  bhs-eta-oem-psdab8841  me2py-am2-oem-nzdab                8892  am-dimephmem-5amo-glyzdap8842  amim-tridi-mes-psdapee             8893  piraz-thizn-no2-zdabs8843  dhim-pazin-eoco-dfzdap             8894  z-dis-cno-bhsdap8844  thpym-eta-no2-bsdap                8895  tolhs-24thiz-imo-bsdap8845  amim-24thizman2-ocho-dfzdap        8896  bim-24thiz-imo-glubzla8846  2py-amn2-5pho-psdab                8897  imhs-din-napo-mezphe8847  pippy-din-5amo-betadcph            8898  bhs-dimen-emo-bhsdab8848  am2py-m25thiz-mes-bsdap            8899  impy-m24thizman2-oem-zdap8849  am2py-25oxman2-emo-zdabs           8900  imhs-amn2-no1-zdab8850  bhs-mea-cpro-bsdap                 8901  ibhs-din-5amo-zdap8851  imhs-eta-no2-bhsdap                8902  z-pipmea-emo-betadcph8852  menim-mepipe-daco-zdabs            8903  thpym-ams2-chexo-bsdap8853  moegua-pipmeo-mommo-bnsdap         8904  thpym-mepipe-no2-bhsdap8854  am4py-diphmep-oem-bsdap            8905  bim-amn2-ocho-zdap8855  2py-pazin-oem-bhsdap               8906  bhs-dis-5pho-zdab8856  hythpym-pazin-5pho-zdabs           8907  dhim-amo2-meo-bphabs8857  me-pipmea-no2-zdabs                8908  tolhs-dis-paco-zdab8858  dpam-mepazin-no1-betadcph          8909  npip-din-5pho-zlys8859  nmor-dis-fo-bphabs                 8910  impy-eta-ocho-zdabs8860  hythpym-edia2-oem-nbetab           8911  pippy-eta-ocho-glyzdap
  naphth                             8912  pippy-amo2-no2-glyzdap8861  phpip-pyma2-mes-mezphe             8913  amim-edian2-no2-dfzdap8862  imhs-n2o2n-eoco-zdap               8914  bimhs-m25thiz-meo-zdabs8863  imhs-eta-no1-zdabs                 8915  thpym-24thiman2-daco-psdap8864  dmbim-m24thiz-napo-betapy          8916  npip-dimephmep-emo-psdap8865  mam2py-diphmep-emo-psdap           8917  am-mepazin-meo-asppha8866  pyraz-trias-meo-mezphe             8918  me2py-dimephmem-ocho-zdapee8867  emnim-24thiz-oem-psdapee           8919  amim-diaz-emo-ibsdap8868  dhim-pnymea-cpeo-zdap              8920  bim-dimephmem-no2-bsdap8869  bim-mepipen2-imo-betadcph          8921  impy-pnymea-fo-betaet8870  pippy-24thizman2-no2-zdab          8922  pyr-ams2-napo-dfzdap8871  nmor-pipmea-men-zdabs              8923  2py-pipmea-eoco-bphabs8872  imhs-mepipe2-oem-npsdap            8924  me2py-mepazin-eoco-osdap8873  bz-amn2-5amo-aval                  8925  thpym-mepipen2-emo-zdap8874  me-ams2-cno-betainyl               8926  am2py-dimephmep-pheo-bsdap8875  bim-pnymea-napo-betadcph           8927  pyrhs-pipmea-men-bsdap8876  bhs-dimephmem-emo-mezphe           8928  bim-pipmea-emo-mezphe8877  chhs-dimephmep-chexo-aval          8929  deam-pipmea-meo-csdap8878  bim-mepipe-mes-zdap                8930  2py-pipmes-fo-psdap8879  gua-am3-sem-nzdap                  8931  dmam-pyma2-men-aspibua8880  cl3pyme-ms-mes-aspbzla             8932  bim-trias-napo-bhsdab8881  imhs-mepipe-fo-psdap               8933  gua-pipmea-4amo-mezphe8882  dmthpym-amn3-eoco-betapy           8934  dhim-pyma2-emo-dfzdap8883  bhs-pazin-oem-psdap                8935  bim-diaz-napo-glyzdap8884  bim-din-4amo-psdap                 8936  edothpym-dimen-5amo-mezphe8885  hythpym-diphmep-ocho-betainyl      8937  amim-amn3-emo-bhsdap8886  dhim-tetradi-mommo-bhsdab          8938  dmam-thizn-no2-zlys8887  nmhs-thizn-5amo-zdab               8939  am2py-m24thizman2-emo-psdap8888  imhs-diphmep-napo-zdab             8940  pippy-am3diaz-hso-dfzdap8889  dhim-thizo-fo-glyzdap              8941  bhs-eta-eoco-zdap8890  bz-dis-no1-aval                    8942  dpam-propn-fo-betadcph8943  me-am2-sem-npsdap                    8994  mam2py-pipmea-men-betadcph8944  im-am2-oem-nbeta34dimeoph            8995  dmam-ams2-no2-aspibua8945  me-n2o2n-eoco-aspaba                 8996  dhim-pipmea-emo-aspibua8946  imhs-tetradi-5pho-bhsdab             8997  2py-ams3-men-aspaba8947  fthpym-n24thiman-napo-psdap          8998  amim-pymea-eoco-aspibua8948  amim-n2nme2n-mes-bhsdab              8999  2py-mepipe-meo-psdap8949  dmthpym-thizn-eoco-zdab              9000  bimhs-thizn-eoco-bhsdap8950  amim-pyma2-cnmo-asppha               9001  impy-pipmea-daco-dfzdap8951  bimhs-n2nme2n-no2-bnsdap             9002  mam2py-24thizman2-oem-psdap8952  cl3pyme-24oxman2-ocho-ibsdap         9003  menim-ams2-oem-oxal8953  amim-ams2-mommo-asppha               9004  bim-edian2-mes-betapy8954  2pmhs-25oxman2-ocho-bsdap            9005  thpym-amn2-5pho-bnsdap8955  hythpym-tridi-no2-bphabs             9006  2py-eta-no1-zdap8956  bimhs-mepazin-5amo-thizzdap          9007  ec-24thiz-chexo-asppha8957  pyrhs-amn3-oeto-asppha               9008  2py-pazin-eoco-zdap8958  imhs-amn2-mes-psdab                  9009  moegua-amo2-5pho-zdab8959  2pmhs-indan2-chexo-psdab             9010  pyrhs-mepazin-oem-csdap8960  pippy-amn3-eoco-psdap                9011  bimhs-am2-sem-npsdap8961  dmthpym-mepazin-chexo-bhsdab         9012  me2py-edia2-sem-nbeta34-8962  mam2py-24thizman2-no2-mezphe               dimeoph8963  pippy-diphmem-cnmo-zdabs             9013  4pmhs-amn3-napo-glyzdap8964  mam2py-amn3-ocho-zdab                9014  me2py-2pazin-5pho-dfzdap8965  me2py-mepipen2-aco-mezphe            9015  bimhs-m24thizman2-napo-csdap8966  bhs-mepipe-paco-zlys                 9016  bim-mepipe-ocho-zdabs8967  dhim-trias-no1-bsdap                 9017  npip-pyma2-fo-betainyl8968  piraz-pnymea-chexo-bhsdap            9018  deam-eta-eoco-csdap8969  dhim-dimephmep-5amo-csdap            9019  4pmhs-pnymea-mes-zdabs8970  n2py-edian2-imo-betadcph             9020  2py-m25thiman2-5amo-zdap8971  thpym-butn-5amo-asppha               9021  2py-25thiz-no2-csdap8972  bim-mepazin-emo-dfzdap               9022  bhs-pipa-4amo-thizzdap8973  me2py-pymea-napo-bnsdap              9023  amim-pipmeo-paco-aspbzla8974  2pmhs-25oxman2-baeo-zdabs            9024  menim-trias-meo-glyzdap8975  bzl-m25thiz-no2-aspbzla              9025  pyrhs-24thiman-men-dfzdap8976  bimhs-25oxman2-emo-betapy            9026  2py-24thiman2-5pho-bnsdap8977  fthpym-diaz-ocho-betapy              9027  thpym-edian2-mes-psdap8978  thpym-eta-no2-zdap                   9028  mam2py-mepipen2-meo-aspibua8979  phpip-m25thiman2-fo-bhsdap           9029  bimhs-pentadi-5amo-betapy8980  me2py-ams2-emo-betadcph              9030  imhs-amn2-imo-zdab8981  pippy-pipmea-no1-bhsdap              9031  nmhs-tridi-chexo-glyzdap8982  piraz-eta-5amo-mezphe                9032  thpym-24thiz-no2-ppsdap8983  hythpym-m24thizman2-men-             9033  hythpym-amn2-5amo-bphabs
  asppha                               9034  am2py-dimephmem-fo-zdabs8984  nim-pnymea-chexo-psdab               9035  pyr-thizn-fo-betapy8985  dhim-tetradi-5pho-betainyl           9036  pippy-ams2-no1-aspbzla8986  amim-amo2-eoco-bhsdap                9037  bz-mepipen2-mes-bnsdap8987  2py-amn2-meo-zdap                    9038  piraz-mepazin-mecpo-betapy8988  thpym-mepipe-mes-zdap                9039  hythpym-amn2-oeto-zdap8989  impy-mepipe-5amo-zdab                9040  piraz-tridi-eoco-psdap8990  bhs-am2-sem-npsdap                   9041  bimhs-pipmea-ocho-betapy8991  menim-m24thiz-eoco-aspbzla           9042  dhim-propa2s-peo-tsdap8992  2pmhs-amo2-hso-bphabs                9043  hythpym-dimephmep-napo-csdap8993  me2py-mepipe2-sem-nbetapy            9044  2py-24thiman2-ocho-bhsdab9045  2pmhs-propn-5pho-betainyl          9097  ec-24thiz-5pho-zdap9046  pippy-eta-mes-betainyl             9098  bim-m25thiman2-chexo-zdabs9047  morhs-eta-chexo-zdap               9099  dpam-pipmea-daco-psdap9048  dmam-n2nme2n-5pho-dfzdap           9100  pippy-m24oxman2-meo-ibsdap9049  4pmhs-m25thiman2-no2-asppha        9101  edothpym-25thiz-chexo-asppha9050  am2py-diphmep-oeto-psdab           9102  mam2py-dimephmep-5pho-ppsdap9051  amthiaz-tetradi-oem-betainyl       9103  bhs-edian2-5pho-zdab9052  prhs-pipmes-5pho-dfzdap            9104  pyr-3pazin-napo-betainyl9053  hythpym-ams2-napo-glyzdap          9105  imhs-dimephmem-men-bphabs9054  bhs-eta-no2-betapy                 9106  bhs-pnymea-napo-bhsdab9055  am2py-pipmea-5amo-bhsdab           9107  am2py-m24thizman2-baeo-9056  phhs-diphmep-cno-bphabs                  aspibua9057  imhs-dimephmem-ocho-bhsdab         9108  ec-m24thizman2-chexo-zorn9058  bzl-24thiz-meo-mezphe              9109  am-mepipe-oem-aspbzla9059  piraz-tridi-no2-bphabs             9110  npip-amo2-5amo-bphabs9060  impy-pipmea-aco-betapy             9111  dmam-pyma2-5pho-asppha9061  me2py-mepazin-emo-bsdap            9112  cl3pyme-pyma2-imo-asppha9062  amim-thizn-5amo-zdab               9113  bimhs-eta2s-no2-aspbzla9063  bim-diphmep-eoco-zdap              9114  pippy-25thiz-napo-psdab9064  bim-pymea-no2-betaet               9115  pippy-ms-5pho-zdap9065  am4py-indan2-5pho-bhsdab           9116  pippy-pentas-no1-dfzdap9066  edothpym-m25thiz-meteto-psdab      9117  bim-amn3-eoco-zdapee9067  ec-edia2-oem-nbeta34dimeoph        9118  moegua-pipmea-napo-psdap9068  pippy-mepazin-peo-bnsdap           9119  bhs-mepipe-meo-psdap9069  impy-25oxman2-meo-mezphe           9120  dhim-trias-5amo-bhsdab9070  dmam-pnymea-mes-zdab               9121  hythpym-n24thiman-eoco-bphabs9071  hythpym-m25thiz-pheo-bsdap         9122  phhs-diphmem-emo-aspaba9072  hythpym-dimephmem-mes-glupha       9123  npip-tetradi-oem-bnsdap9073  imhs-edian2-mes-zdab               9124  imhs-tridi-chexo-bhsdab9074  amim-tridi-ocho-bhsdap             9125  piraz-pnymea-napo-psdab9075  amim-pyma2-daco-betapy             9126  piraz-edia2-oem-nbetapy9076  dhim-pipa-no1-bsdap                9127  bim-amn2-5pho-bnsdap9077  thpym-mepazin-imo-zdabs            9128  impy-pipmeo-pro-asppha9078  imhs-eta-oem-bsdap                 9129  piraz-m24thizman2-cpro-tsdap9079  n2py-24thizman2-no2-bnsdap         9130  am2py-diphmem-emo-ppsdap9080  mam2py-dimen-napo-glupha           9131  am4py-pnymea-oem-aspbzla9081  bzl-trias-meo-mezphe               9132  bhs-mepipen2-pro-betadcph9082  bhs-pazin-mes-bnsdap               9133  2py-pymea-ocho-aspibua9083  bhs-24thiz-hso-zdap                9134  me2py-pipmea-fo-zdab9084  pyrhs-eta-eoco-betainyl            9135  cl3pyme-pymea-fo-zdabs9085  mepip-25oxman2-no2-zdabs           9136  me2py-m24thizman2-no1-zdab9086  imhs-amn2-ocho-bhsdap              9137  pippy-25oxman2-no2-mezphe9087  me2py-pipmea-oem-zdab              9138  bhs-pyma2-men-csdap9088  hythpym-ams2-no2-glyzdap           9139  imhs-m25thizman2-no2-betapy9089  thpym-edian2-5pho-betapy           9140  2py-ams2-hso-psdab9090  im-hexadi-no1-bphabs               9141  dhim-25thizman2-imo-bhsdab9091  pippy-tridi-emo-zdabs              9142  bimhs-dimen-mes-zdap9092  hythpym-m25thiz-men-bnsdap         9143  am-pyma2-fo-betainyl9093  thpym-dimephmem-imo-mezphe         9144  am-dimen-eoco-zdap9094  impy-indan2-pyo-bhsdap             9145  menim-am3-sem-nbetameph9095  dpam-tridi-mommo-mezphe            9146  pippy-amo2-eoco-psdab9096  thpym-diphmem-no2-bphabs           9147  bhs-m24thiz-oem-zdabs9148  imhs-pazin-oem-bnsdap              9200  bhs-amn2-mes-psdap9149  morhs-pnymea-meteto-psdab          9201  ec-thizn-emo-aspbzla9150  amim-edia2-oem-nzdap               9202  amim-n24thiman-daco-bhsdab9151  dhim-m24thiz-cpeo-bsdap            9203  dpam-amn2-imo-asppha9152  mam2py-m25thizman2-mes-betapy      9204  imhs-24thizman2-cpro-asppha9153  chhs-diphmep-5amo-tsdap            9205  imhs-edian2-meo-bsdap9154  z-diphmem-no2-bnsdap               9206  2py-amn2-men-betadcph9155  bimhs-edia2-oem-nbetabnaphth       9207  thpym-am2-sem-nbetapy9156  amim-pnymea-napo-bsdap             9208  bhs-m25thiz-5amo-aspibua9157  piraz-pazin-emo-bnsdap             9209  im-n2o2n-5pho-zdab9158  am2py-din-eoco-bnsdap              9210  piraz-25oxman2-pro-bhsdap9159  menim-tridi-no2-bhsdap             9211  mam2py-mepipe-daco-csdap9160  mepip-pymea-pheo-betapy            9212  fthpym-m24thiman2-napo-betapy9161  imhs-amn2-meo-zdab                 9213  imhs-eta-mes-betapy9162  amim-pipa-fo-zdapee                9214  bimhs-m24thizman2-men-zdabs9163  me2py-diphmem-no1-zlys             9215  hythpym-diphmep-oeto-aspibua9164  thpym-eta-oem-bhsdap               9216  dpam-m25thiz-no2-mezphe9165  phhs-amn3-eoco-osdap               9217  pyr-24oxman2-napo-bphabs9166  imhs-thizn-oem-aspibua             9218  piraz-mepipe-no1-bnsdap9167  pippy-diphmem-cno-betapy           9219  hythpym-mepipe-oem-psdab9168  phhs-tetradi-men-psdap             9220  hythpym-25thiman2-4pho-mezphe9169  pyraz-dimen-cpeo-psdapee           9221  cl3pyme-thizs-cnmo-csdap9170  bz-pnymea-eoco-zdap                9222  me2py-edian2-5amo-glupha9171  imhs-dis-ocho-psdap                9223  amim-trias-imo-asppha9172  bim-thizn-baeo-mezphe              9224  hythpym-m25thiz-emo-zdap9173  imhs-pipmea-mes-psdap              9225  piraz-pyma2-meo-zdap9174  piraz-pipmea-no1-csdap             9226  dhim-m25thiman2-aco-psdab9175  bimhs-mea2s-cpro-bnsdap            9227  thpym-mepipe-meo-psdab9176  bim-edian2-no2-zdab                9228  bimhs-din-no2-zdab9177  mam2py-dimephmep-emo-betadcph      9229  amim-am2-oem-nzdap9178  am2py-mepazin-oeto-csdap           9230  impy-pyma2-daco-glyzdap9179  2py-amn2-ocho-psdab                9231  bimhs-eta-ocho-bhsdab9180  me2py-dimephmep-imo-aspaba         9232  prhs-mea2s-no1-asppha9181  ec-24thizman2-ocho-bphabs          9233  mam2py-25oxman2-napo-dfzdap9182  bz-thizn-fo-zdab                   9234  gua-thizn-eoco-bphabs9183  impy-m24thiz-oem-betadcph          9235  phpip-eta-men-bhsdap9184  pyraz-dimephmem-4amo-psdab         9236  mam2py-dimephmem-5amo-glyzdap9185  hythpym-pipa-5amo-betapy           9237  pippy-dis-ocho-psdap9186  4pmhs-hexas-mes-bhsdap             9238  bimhs-m24thizman2-no2-dfzdap9187  me2py-25thizman2-5amo-csdap        9239  amim-m25thiz-pyo-csdap9188  tolhs-amn3-men-bnsdap              9240  me2py-pymea-eoco-bsdap9189  mam2py-thizn-ocho-csdap            9241  piraz-dimephmem-chexo-bhsdab9190  thpym-ams2-mes-aspbzla             9242  2py-ms-mes-psdab9191  2py-edian2-oem-zdab                9243  pyr-dimephmem-mes-glyzdap9192  nnhs-amo2-napo-bhsdab              9244  impy-pymea-oem-bnsdap9193  bhs-mepazin-daco-zdabs             9245  2pmhs-diphmem-5amo-bsdap9194  dhim-eta2s-meo-zdabs               9246  bimhs-pipmea-fo-bsdap9195  mepip-dimen-mes-bnsdap             9247  dmam-thizn-no1-zdabs9196  pippy-thizn-fo-bhsdap              9248  mepip-dis-cpeo-betadcph9197  mam2py-edia2-oem-npsdap            9249  2py-din-meo-osdap9198  thpym-thizo-no2-zdap               9250  menim-pnymea-oeto-bphabs9199  npip-mea-emo-dfzdap                9251  am2py-hexas-napo-bohabs9252  impy-ams2-mes-mezphe                9302  imhs-dimen-ocho-glupha9253  thpym-pazin-pheo-dfzdap             9303  pippy-24thiz-oem-zdap9254  thpym-mepazin-ocho-betadcph         9304  impy-amo2-mes-bnsdap9255  pyraz-mepipen2-napo-aspibua         9305  mepip-mepazin-fo-betapy9256  bz-amn3-men-zdabs                   9306  pippy-tridi-oem-bsdap9257  amim-pymea-pyo-mezphe               9307  prhs-mepazin-emo-asppha9258  4pmhs-mepipe-no2-zdabs              9308  mam2py-din-cnmo-bhsdap9259  bhs-amo2-baeo-dfzdap                9309  bimhs-amo2-mecpo-psdap9260  phpip-amn2-no1-dfzdap               9310  bim-eta-mes-zdab9261  me2py-edia2-sem-nzdap               9311  hythpym-pipmea-no1-glyzdap9262  amthiaz-24thizman2-                 9312  impy-amn3-chexo-oxal
  imo-aspbzla                         9313  npip-eta-no1-bsdap9263  ibhs-tetradi-oem-betadcph           9314  me2py-dimephmem-mes-bhsdap9264  2py-mepipen2-eoco-bhsdab            9315  impy-diphmem-mommo-csdap9265  dmam-dimen-no2-betainyl             9316  pippy-m24thiz-mes-betadcph9266  dmthpym-dimephmep-5pho-mezphe       9317  dhim-pipa-fo-thizzdap9267  ec-ams2-mes-psdab                   9318  cl3pyme-edia2-sem-nbetab9268  2py-eta-mes-zdap                          naphth9269  nmhs-diphmem-daco-psdab             9319  hythpym-24thizman2-oem-osdap9270  mepip-mepipe-chexo-asppha           9320  bimhs-mea-chexo-betadcph9271  2py-24thiz-emo-bhsdap               9321  imhs-mepipe-no2-bhsdap9272  imhs-amn2-oem-bnsdap                9322  me2py-dimephmem-mes-dfzdap9273  impy-thizn-meo-bhsdab               9323  bim-mepipen2-oem-zdabs9274  mam2py-tetradi-imo-zdab             9324  me2py-amo2-meo-aspibua9275  dhim-eta-oem-ppsdap                 9325  4pmhs-24thiz-napo-zdab9276  bim-amo2-ocho-dfzdap                9326  chmhs-24thizman2-ocho-glubzla9277  imhs-pazin-mes-bnsdap               9327  thpym-edian2-mes-psdab9278  bz-dimephmem-ocho-betapy            9328  bhs-eta-5pho-psdap9279  pippy-25oxman2-pheo-bphabs          9329  4pmhs-am3-sem-nzdap9280  thpym-mepipe-oem-betainyl           9330  amim-pipa-imo-ibsdap9281  bim-3diaz-5pho-glyzdap              9331  bimhs-pipmea-5pho-betapy9282  piraz-m24thizman2-hso-oxal          9332  hythpym-dimephmem-mes-bphabs9283  menim-m25thiz-eoco-aspbzla          9333  amthiaz-tetradi-5amo-psdab9284  z-din-no2-aspibua                   9334  am2py-pazin-hso-mezphe9285  nmor-tetradi-4pho-csdap             9335  am2py-din-ocho-mezphe9286  dhim-pymea-men-betapy               9336  imhs-mepipe-oem-betapy9287  me-pnymea-fo-asppha                 9337  amthiaz-tetradi-no1-mezphe9288  tolhs-amo2-no1-psdab                9338  dhim-am2-sem-nbetabnaphth9289  imhs-eta-ocho-bnsdap                9339  piraz-edian2-daco-zdab9290  2pmhs-m24thizman2-ocho-psdab        9340  impy-amo2-eoco-bnsdap9291  am-edian2-5amo-zdab                 9341  am2py-amo2-eoco-csdap9292  thpym-eta-no2-bnsdap                9342  dhim-amn2-eoco-zdap9293  pyr-24thizman2-chexo-bhsdap         9343  phpip-3diaz-5pho-bsdap9294  pyrhs-dimephmem-peo-dfzdap          9344  2py-pazin-no1-zdap9295  morhs-pazin-meteto-mezphe           9345  dmbim-24thiz-imo-bnsdap9296  mam2py-24thizman2-meteto-           9346  moegua-24thizman2-no1-betapy
  bnsdap                              9347  deam-pipmea-fo-zdab9297  impy-edian2-4pho-zdabs              9348  piraz-dimephmem-napo-aspbzla9298  amim-ams2-5pho-dfzdap               9349  thpym-dis-nmo-betapy9299  thpym-edian2-eoco-psdab             9350  dhim-n24thiman-chexo-mezphe9300  amthiaz-pazin-oem-bhsdap            9351  bz-mepazin-ocho-aval9301  2py-pentas-cnmo-betainyl            9352  phhs-m24thiman2-baeo-psdapee9353  cl3pyme-din-imo-dfzdap             9404  2py-25oxman2-meto-aspibua9354  hythpym-pymea-eoco-bhsdap          9405  bim-din-meteto-zdabs9355  bhs-amn2-meto-dfzdap               9406  dmthpym-thizn-imo-glyzdap9356  bim-amn2-oem-bhsdap                9407  bim-din-fo-bhsdab9357  am-dimephmem-fo-betainyl           9408  mam2py-ams3-mes-thizzdap9358  dpam-pipmes-napo-zdabs             9409  piraz-din-napo-betapy9359  chmhs-diphmem-chexo-glubzla        9410  chhs-dimephmem-ocho-betapy9360  imhs-thizs-5amo-mezphe             9411  me2py-din-mes-ibsdap9361  bim-amo2-hso-asppha                9412  am-24thizman2-baeo-asppha9362  bhs-ams2-no1-bhsdap                9413  thpym-edian2-no1-bsdap9363  am2py-trias-mmen-psdap             9414  bhs-pymea-4amo-betainyl9364  amim-amn2-meteto-zdabs             9415  dhim-butn-fo-betainyl9365  pippy-eta-pheo-betapy              9416  mam2py-25oxman2-5amo-betadcph9366  2py-indan2-imo-aspibua             9417  bim-amn2-no1-psdab9367  bim-diphmep-fo-zorn                9418  thpym-24thiz-fo-zdabs9368  bhs-edian2-ocho-zdap               9419  dhim-n2nme2n-pheo-oxal9369  thpym-edian2-oem-psdab             9420  amim-n2o2n-cpeo-bnsdap9370  bimhs-24thizman2-chexo-ibsdap      9421  pippy-trias-napo-glupha9371  n2py-25oxman2-chexo-mezphe         9422  me2py-amn2-no2-bphabs9372  amim-pentas-no2-bnsdap             9423  gua-dis-5amo-dfzdap9373  2py-m25thiz-oem-glyzdap            9424  am2py-m25thiz-eoco-zdabs9374  npip-mepipe2-sem-nbetapy           9425  me2py-trias-imo-asppha9375  am2py-m25thiz-men-bhsdab           9426  amim-pymea-imo-csdap9376  imhs-eta-no1-bnsdap                9427  imhs-pazin-oem-psdab9377  bhs-edian2-no1-betapy              9428  fthpym-pentas-hso-dfzdap9378  pippy-m25thiz-cno-betapy           9429  2py-pazin-no2-bhsdap9379  hythpym-24oxman2-oem-bphabs        9430  pippy-pipmes-cno-psdapee9380  bimhs-thizo-5pho-glyzdap           9431  me2py-dimephmem-oem-ppsdap9381  mam2py-mepazin-men-betapy          9432  chmhs-am3diaz-eoco-betadcph9382  bimhs-ams3-chexo-betapy            9433  emnim-amn2-mes-oxal9383  edothpym-edia2-oem-npsdap          9434  chhs-m25thiz-oem-betainyl9384  pyrhs-amo2-imo-tsdap               9435  am-thizn-mmen-aspbzla9385  dhim-mepipe2-sem-nbetabnaphth      9436  bim-mepipe-meo-bhsdap9386  bim-mepipe-meo-bnsdap              9437  2py-thizn-daco-glyzdap9387  bim-amo2-meo-bsdap                 9438  pippy-mepipe-oeto-glyzdap9388  am2py-edia2-oem-nbeta34-           9439  impy-tridi-ocho-betadcph
  dimeoph                            9440  mam2py-25oxman2-4amo-psdap9389  pyr-24thiz-no1-bphabs              9441  bhs-pipmeo-napo-bnsdap9390  am2py-2pazin-napo-zorn             9442  mam2py-mepipe2-sem-nzdap9391  imhs-24thizman2-pro-glyzdap        9443  bhs-mepipen2-mes-asppha9392  thpym-mepipen2-5pho-ibsdap         9444  bhs-mea-no2-ibsdap9393  moegua-mepazin-no1-bnsdap          9445  thpym-edian2-5pho-bnsdap9394  me2py-amn2-cnmo-zdabs              9446  2pmhs-24thiman2-eoco-glyzdap9395  impy-dis-imo-bhsdap                9447  am2py-25oxman2-ocho-betapy9396  pippy-dimen-no2-aspbzla            9448  me2py-am3diaz-ocho-bhsdab9397  pippy-n24thiman-5pho-betainyl      9449  dpam-amo3-men-zdab9398  imhs-pipmea-imo-mezphe             9450  me2py-pipa-fo-csdap9399  dpam-dich-no2-psdab                9451  thpym-props-chexo-betainyl9400  thpym-din-5amo-psdap               9452  am2py-24thiman2-men-dfzdap9401  imhs-24thiman-eoco-zdab            9453  thpym-edian2-no2-psdap9402  pippy-mepazin-5amo-zdab            9454  npip-2pazin-mmen-csdap9403  mam2py-ams2-paco-bsdap             9455  bim-edian2-no1-bhsdap9456  im-pnymea-cpeo-mezphe              9508  pippy-pazin-no2-betapy9457  hythpym-amn3-chexo-zorn            9509  edothpym-pazin-no1-asppha9458  2py-din-no1-betainyl               9510  bimhs-pazin-men-dfzdap9459  imhs-pazin-oem-bsdap               9511  dhim-mepipen2-fo-glyzdap9460  dhim-mepazin-nmo-bsdap             9512  am-butn-5amo-psdab9461  nmor-25oxman2-cpro-bsdap           9513  dhim-pipmea-pyo-betapy9462  hythpym-amo2-emo-zdap              9514  pippy-m24thizman2-ocho-zdabs9463  hythpym-amn2-no1-glupha            9515  thpym-amn2-emo-aspbzla9464  2py-pnymea-chexo-betainyl          9516  bhs-mepipe2-sem-nzdab9465  dmbim-24thiz-imo-betainyl          9517  edothpym-25thiz-emo-aspbzla9466  hythpym-diphmem-emo-zdap           9518  gua-24thiz-5amo-asppha9467  menim-mepazin-meo-psdab            9519  imhs-pazin-imo-asppha9468  me2py-25oxman2-ocho-bnsdap         9520  phhs-diphmem-cpeo-psdab9469  bim-edian2-no2-psdap               9521  am4py-tridi-oem-zdab9470  am2py-mepipen2-meteto-glyzdap      9522  2pmhs-m24thizman2-chexo-9471  imhs-ams3-5pho-betapy                    betadcph9472  amim-m24thiz-5pho-glyzdap          9523  mepip-m24oxman2-men-betainyl9473  pippy-dimen-no1-psdap              9524  hythpym-amo2-no2-betapy9474  me2py-tridi-imo-zlys               9525  2pmhs-mepipe-ocho-mezphe9475  bhs-mepipe-no1-zdab                9526  z-ams2-ocho-mezphe9476  impy-dimephmem-napo-bsdap          9527  4pmhs-n24thiman-oem-zdapee9477  edothpym-thizs-no1-bnsdap          9528  fthpym-mepipen2-meteto-zdab9478  pyr-pyma2-napo-psdapee             9529  dhim-edian2-eoco-csdap9479  2py-pazin-no1-bnsdap               9530  hythpym-pipa-hso-bhsdap9480  bzl-diaz-imo-csdap                 9531  ppy-n2nme2n-5pho-dfzdap9481  piraz-tridi-imo-asppha             9532  imhs-mepazin-cno-zdabs9482  hythpym-ams2-paco-aspbzla          9533  bimhs-24thizman2-nmo-betaet9483  mam2py-mepipe-mes-psdab            9534  ppy-eta-eoco-psdap9484  imhs-pyma2-no1-bphabs              9535  fthpym-hexas-no1-csdap9485  impy-ms-oem-bhsdap                 9536  me-tetras-eoco-bhsdab9486  dhim-dimen-men-aspibua             9537  2py-ams2-peo-bhsdab9487  piraz-dimephmem-emo-asppha         9538  amthiaz-diaz-emo-bnsdap9488  bhs-pazin-mes-bhsdap               9539  hythpym-tetradi-cnmo-zdabs9489  bim-tridi-meteto-zdab              9540  bz-amo2-emo-bsdap9490  2py-amn3-men-betainyl              9541  bhs-eta-pheo-mezphe9491  pippy-amn3-aco-psdap               9542  chmhs-3pazin-no2-glyzdap9492  dhim-tetradi-mmen-betapy           9543  2py-dimen-cno-csdap9493  ibhs-dimen-imo-psdapee             9544  emnim-thizn-meteto-bsdap9494  thpym-din-eoco-zdap                9545  imhs-pazin-no2-betapy9495  bhs-edian2-5pho-bhsdap             9546  2py-m24thizman2-eoco-zdabs9496  am2py-diphmep-meo-bhsdab           9547  chmhs-pymea-cpro-betainyl9497  am2py-am2-oem-nzdap                9548  pyraz-n2nme2n-napo-aspbzla9498  2py-pazin-mes-osdap                9549  impy-diphmep-imo-aspibua9499  dhim-ams2-paco-mezphe              9550  impy-pazi2n-chexo-zdabs9500  bz-ams2-pyo-bhsdab                 9551  thpym-eta-no1-betapy9501  2py-trias-no1-aspbzla              9552  edothpym-pnymea-men-dfzdap9502  me2py-m25thiz-no2-zdab             9553  mam2py-ams2-cpeo-psdap9503  am2py-pipmea-4pho-betainyl         9554  nmhs-edian2-eoco-aspibua9504  piraz-24thizman2-mes-zdapee        9555  mam2py-dipch-no2-zdabs9505  amim-dipch-5pho-bnsdap             9556  bhs-pazin-ocho-bsdap9506  am2py-diphmep-ocho-bsdap           9557  thpym-edian2-no1-psdap9507  2py-amn2-no1-bhsdap                9558  bimhs-dimephmep-no2-psdab9559  ec-24thiman-imo-glyzdap               9610  piraz-25oxman2-fo-zdabs9560  mam2py-tetradi-meteto-                9611  pyr-3diaz-oem-psdab
  betadcph                              9612  phhs-m25oxman2-no2-zdab9561  mam2py-dimephmep-no1-betaet           9613  2py-mepipe-4amo-betapy9562  nmhs-amn2-men-asppha                  9614  thpym-m24oxman2-5amo-bhsdap9563  pippy-dis-cnmo-bsdap                  9615  dhim-mepazin-aco-psdap9564  mam2py-amn3-oem-psdap                 9616  mam2py-3diaz-cno-betapy9565  am2py-din-no2-dfzdap                  9617  piraz-pymea-fo-zdabs9566  ibhs-m25oxman2-eoco-csdap             9618  am2py-dimephmem-ocho-bhsdap9567  me2py-m24thiz-5amo-zdab               9619  emnim-m24oxman2-fo-zdabs9568  pippy-tetradi-paco-bnsdap             9620  bim-amn2-mes-bsdap9569  impy-25oxman2-5amo-aval               9621  2py-pazin-no1-bhsdap9570  emnim-tetradi-no1-aspbzla             9622  dhim-amn2-ocho-ibsdap9571  pippy-dimephmem-fo-aspaba             9623  piraz-eta-napo-oxal9572  tolhs-dimephmem-5pho-psdap            9624  ppy-pymea-no2-psdap9573  bimhs-eta-men-tsdap                   9625  mam2py-25thiman2-5pho-bphabs9574  ec-dis-oem-glyzdap                    9626  pyraz-edian2-meo-aspibua9575  bim-tetradi-mes-aval                  9627  thpym-mepipe-no1-bhsdap9576  dmthpym-mepipen2-5amo-zdapee          9628  2py-props-napo-bhsdap9577  z-mepipe2-sem-nzdab                   9629  phpip-din-emo-betapy9578  bimhs-pazin-mmen-psdap                9630  bhs-diphmep-mecpo-zdab9579  edothpym-dimen-mes-ppsdap             9631  deam-tetradi-mes-psdab9580  am2py-m24oxman2-pheo-zdap             9632  dhim-thizn-eoco-bphabs9581  thpym-mepazin-meo-zdab                9633  amthiaz-thizo-oem-bhsdap9582  thpym-tridi-ocho-aspibua              9634  bhs-pnymea-5amo-mezphe9583  am4py-ams2-napo-betapy                9635  thpym-mepipe-ocho-zdap9584  impy-dipch-chexo-bsdap                9636  thpym-dimephmem-mes-csdap9585  mam2py-pipmea-meo-psdap               9637  nmhs-amn3-eoco-bphabs9586  me2py-din-no2-csdap                   9638  bhs-eta-mes-bhsdap9587  dhim-pyma2-no1-bhsdap                 9639  am2py-amn3-meo-bphabs9588  impy-amo2-fo-aspbzla                  9640  bim-dimephmep-fo-aspbzla9589  bimhs-amn2-meteto-zdapee              9641  dpam-pipa-fo-bphabs9590  bim-tridi-mmen-mezphe                 9642  amim-pnymea-men-aspibua9591  imhs-mepipe-5pho-betapy               9643  thpym-diphmep-chexo-betainyl9592  cl3pyme-edia2-sem-nbetapy             9644  bim-amn2-ocho-psdab9593  pippy-mepipe2-sem-nzdap               9645  dhim-eta-no2-csdap9594  ibhs-m25thiz-meo-zdab                 9646  morhs-amo3-meo-aval9595  2pmhs-trias-ocho-bsdap                9647  piraz-ams2-nmo-bhsdab9596  thpym-dimephmem-no1-betadcph          9648  n2py-dis-imo-psdap9597  pyraz-dimen-men-glubzla               9649  bhs-thizn-napo-bnsdap9598  bim-eta-no1-bnsdap                    9650  2py-pymea-5pho-zdabs9599  2py-mepipen2-men-bsdap                9651  dmthpym-din-napo-ibsdap9600  tolhs-pipa-no2-betaet                 9652  dpam-m24oxman2-meo-zdab9601  mam2py-eta-mmen-bsdap                 9653  thpym-mepipe-oem-zdap9602  morhs-m24oxman2-fo-csdap              9654  2py-mepipe-mes-zdap9603  pyr-m25thiz-imo-asppha                9655  moegua-m24thizman2-9604  bhs-mea2s-fo-mezphe                         chexo-aspbzla9605  amim-dis-eoco-mezphe                  9656  deam-dis-pro-glyzdap9606  bim-hexadi-peo-bsdap                  9657  bhs-pazin-no2-bnsdap9607  dhim-din-5pho-bsdap                   9658  mam2py-m25thiz-no1-aspibua9608  amim-amn2-no2-betainyl                9659  dhim-amn2-imo-zdabs9609  hythpym-mepipe-daco-aspibua           9660  phpip-amo2-meo-bnsdap9661  prhs-tetradi-meo-glyzdap            9713  amim-n2o2n-oem-bsdap9662  bimhs-thizn-imo-zdabs               9714  tolhs-amn2-5amo-thizzdap9663  2py-eta-ocho-zdab                   9715  bhs-edian2-napo-aspbzla9664  me2py-tetradi-meo-betainyl          9716  n2py-24thiz-eoco-zdabs9665  dhim-m25thiz-meto-aspibua           9717  hythpym-eta-5pho-oxal9666  n2py-pymea-pro-mezphe               9718  dhim-eta-4pho-asppha9667  chhs-pymea-4pho-bhsdab              9719  bim-am2-sem-nbetabnaphth9668  amim-pipa-cpeo-betainyl             9720  mam2py-eta-eoco-zorn9669  thpym-amn2-no2-psdab                9721  dhim-mepazin-no1-bphabs9670  thpym-dimen-mes-zdabs               9722  prhs-din-meto-glupha9671  cl3pyme-trias-chexo-psdap           9723  hythpym-pipmeo-napo-betapy9672  chmhs-thizn-5amo-aspbzla            9724  amthiaz-dimephmep-no2-9673  imhs-pipmea-ocho-betainyl                 betainyl9674  amim-ams3-ocho-bphabs               9725  fthpym-m24thizman2-5amo-9675  ibhs-m24thizman2-meto-bsdap               dfzdap9676  piraz-24thiz-napo-csdap             9726  impy-pnymea-men-zdap9677  nmhs-edian2-no2-asppha              9727  mepip-diaz-daco-bhsdap9678  deam-m25thiz-fo-csdap               9728  dpam-pipmea-no2-zdabs9679  bz-thizn-ocho-bnsdap                9729  bimhs-m24thiz-oeto-bphabs9680  2py-amo3-chexo-bnsdap               9730  amim-mepazin-eoco-dfzdap9681  amim-mepipe-mmen-thizzdap           9731  im-amo2-fo-glyzdap9682  fthpym-diaz-mes-betapy              9732  moegua-eta-fo-aspbzla9683  me2py-mepazin-5pho-psdab            9733  bhs-edian2-no2-betapy9684  am-25oxman2-no1-bhsdap              9734  nmor-amn3-men-oxal9685  thpym-mepipe-ocho-bhsdap            9735  dmthpym-dimen-eoco-psdab9686  bimhs-pyma2-5amo-ppsdap             9736  am2py-m25thiman2-ocho-aval9687  thpym-am3diaz-imo-mezphe            9737  bz-amo2-no1-psdap9688  dmam-mepipe2-oem-nzdap              9738  nmhs-edian2-mmen-zdapee9689  dpam-trias-no1-csdap                9739  piraz-m24thizman2-ocho-psdab9690  dmam-tetradi-napo-betadcph          9740  dmbim-24thiman-pyo-aspbzla9691  imhs-edian2-no2-zdab                9741  bim-tridi-no2-bphabs9692  pyr-pipmea-4amo-psdapee             9742  phpip-din-imo-betadcph9693  morhs-m25thiz-chexo-zdabs           9743  me2py-diphmep-4pho-aspbzla9694  dhim-mepipe-oem-bnsdap              9744  imhs-edian2-mes-psdap9695  hythpym-tetradi-mes-bhsdab          9745  2py-pazin-no1-bsdap9696  bim-thizo-men-psdab                 9746  prhs-trias-imo-csdap9697  bz-pnymea-no1-glyzdap               9747  bhs-edian2-oem-psdap9698  dhim-pyma2-eoco-asppha              9748  pippy-m24thizman2-chexo-9699  ibhs-amo2-mecpo-csdap                     betapy9700  bhs-dimen-men-bsdap                 9749  2py-tridi-napo-asppha9701  4pmhs-amn3-meo-bphabs               9750  fthpym-amn2-pyo-bhsdap9702  hythpym-24thiman-cno-bhsdap         9751  amim-dis-no2-aspibua9703  bimhs-mepazin-4pho-zdap             9752  piraz-pipa-no1-betainyl9704  bimhs-propn-pheo-bnsdap             9753  mam2py-tridi-napo-psdap9705  pippy-tetradi-meo-glyzdap           9754  bimhs-25oxman2-nmo-bhsdap9706  thpym-eta-eoco-zdap                 9755  2py-mepipe-no1-bnsdap9707  imhs-pazin-ocho-betapy              9756  am2py-pipmea-meo-zdab9708  thpym-pipmes-no1-ibsdap             9757  pyr-pyma2-men-dfzdap9709  edothpym-indan2-cno-psdap           9758  bzl-24thiz-no2-aspibua9710  me2py-diphmep-meteto-aspbzla        9759  bhs-eta-no2-bphabs9711  thpym-pazin-mes-bnsdap              9760  tolhs-amn2-fo-aspibua9712   me-pnymea-men-psdab                9761  am2py-mepazin-mes-dfzdap9762  pippy-din-meto-betapy               9814  piraz-dimephmem-no1-aspibua9763  piraz-butn-cpeo-zdap                9815  mam2py-dimen-imo-csdap9764  imhs-eta-oem-betapy                 9816  thpym-din-fo-glubzla9765  amim-am2-oem-nzdab                  9817  imhs-amn2-oem-psdab9766  hythpym-tetradi-mes-bhsdab          9818  prhs-pipa-no2-bnsdap9767  impy-eta-napo-bhsdap                9819  thpym-eta-oem-psdab9768  thpym-pyma2-meo-bphabs              9820  me2py-pnymea-eoco-zdab9769  bhs-mepipen2-mes-bhsdap             9821  edothpym-edia2-oem-nbetab9770  am4py-amn2-men-dfzdap                     naphth9771  n2py-25oxman2-mes-aspbzla           9822  fthpym-butn-ocho-zorn9772  nim-tridi-5amo-bsdap                9823  n2py-edian2-emo-mezphe9773  me2py-din-fo-psdab                  9824  thpym-eta-no2-bhsdap9774  bim-mepipe-no2-bsdap                9825  dhim-amn3-mes-aspbzla9775  amim-24thiz-fo-psdab                9826  pyr-edia2-oem-nzdab9776  me2py-pipa-meo-bhsdap               9827  bhs-mepipen2-chexo-bphabs9777  dmthpym-m25thiz-no2-bphabs          9828  bhs-24thiman-baeo-zdab9778  amim-din-men-csdap                  9829  morhs-mepipe2-sem-nbetab9779  pippy-diaz-no2-bhsdab                     naphth9780  am2py-pipmeo-ocho-zdabs             9830  me2py-trias-5amo-betainyl9781  bimhs-dimephmem-napo-glubzla        9831  ppy-thizn-nmo-ibsdap9782  imhs-dimephmep-meo-asppha           9832  thpym-eta-no1-asppha9783  pippy-m24thizman2-5pho-bnsdap       9833  2py-amn2-5pho-psdap9784  n2py-tridi-oem-csdap                9834  piraz-pazin-napo-bphabs9785  me2py-24thizman2-cpro-asppha        9835  am2py-thizn-eoco-asppha9786  bim-eta-no2-bsdap                   9836  bim-pipmea-napo-zdap9787  bim-am2-oem-nzdab                   9837  dhim-dimephmem-emo-psdab9788  dhim-24thizman2-men-mezphe          9838  dpam-diphmem-emo-psdab9789  pyrhs-n2o2n-5amo-betadcph           9839  bz-n2o2n-daco-bnsdap9790  me-ams2-eoco-bhsdab                 9840  bhs-amn3-meteto-betainyl9791  dhim-dimephmem-meo-csdap            9841  imhs-edian2-oem-glyzdap9792  am2py-mepipe-paco-csdap             9842  dhim-pipmea-fo-aspaba9793  pyraz-mepipen2-meo-betapy           9843  bimhs-diphmem-fo-bhsdap9794  npip-eta-pro-bsdap                  9844  am2py-pipa-mmen-betapy9795  amim-edian2-4pho-aspibua            9845  ppy-m25thiz-fo-bhsdab9796  phhs-pipmea-men-aspbzla             9846  me2py-edian2-napo-aspbzla9797  piraz-dis-men-bphabs                9847  z-dimephmem-men-thizzdap9798  2py-m25thiz-5pho-bsdap              9848  bzl-amn3-meo-aspibua9799  hythpym-pymea-oem-aspbzla           9849  imhs-edian2-oem-bhsdap9800  impy-thizn-men-dfzdap               9850  bim-edian2-mes-zdab9801  mam2py-24thiz-oem-betapy            9851  dhim-diphmem-fo-zdap9802  2py-amn2-no2-zdabs                  9852  prhs-ams2-mes-mezphe9803  amthiaz-pazin-no1-zdap              9853  mam2py-dimephmem-meo-betadcph9804  bhs-25oxman2-ocho-bnsdap            9854  moegua-3diaz-no2-psdap9805  thpym-pazin-meo-zdap                9855  piraz-dis-5pho-betainyl9806  hythpym-trias-fo-betapy             9856  imhs-pipa-eoco-aspibua9807  pyr-dimephmem-cpro-bhsdab           9857  chhs-pazin-cpro-bnsdap9808  prhs-eta-fo-betadcph                9858  emnim-24thiz-no1-mezphe9809  bim-eta-no1-bsdap                   9859  me-am3-oem-nbetameph9810  hythpym-pipmea-fo-aspbzla           9860  amim-tetradi-emo-glubzla9811  z-eta-pro-zlys                      9861  thpym-pazin-5pho-zdab9812  imhs-dis-chexo-dfzdap               9862  piraz-n2nme2n-mes-csdap9813  am2py-25oxman2-napo-dfzdap          9863  dhim-mea2s-napo-csdap9864  edothpym-thizo-pro-betainyl        9916  am2py-ams2-imo-psdab9865  amthiaz-amo2-men-betapy            9917  dhim-dimephmep-chexo-mezphe9866  me2py-amn2-baeo-asppha             9918  ec-edian2-5pho-bnsdap9867  imhs-mepipe-5pho-bnsdap            9919  chmhs-am3-oem-nzdap9868  mam2py-mepazin-napo-zdap           9920  2py-eta-oem-psdap9869  dhim-dich-mes-psdab                9921  bhs-mepipe-ocho-psdab9870  thpym-tridi-mes-betapy             9922  cl3pyme-pyma2-men-betapy9871  thpym-trias-5amo-bphabs            9923  bimhs-diphmem-mes-tsdap9872  chmhs-dis-4pho-bsdap               9924  thpym-pyma2-fo-oxal9873  bhs-eta-eoco-bhsdap                9925  bimhs-mepazin-eoco-aspbzla9874  pippy-am2-oem-nbetapy              9926  tolhs-eta-chexo-aspbzla9875  ibhs-mepazin-4pho-betapy           9927  am4py-24oxman2-4pho-csdap9876  imhs-dimephmep-pyo-zdap            9928  me2py-trias-men-bsdap9877  imhs-mepipe-meo-bsdap              9929  bhs-ams3-ocho-psdap9878  thpym-pnymea-ocho-zdapee           9930  pippy-24thiz-fo-dfzdap9879  bhs-pazin-mes-zdap                 9931  piraz-24thizman2-hso-bsdap9880  imhs-mepipe-5pho-zdap              9932  imhs-m24thizman2-peo-asppha9881  bzl-thizo-eoco-betainyl            9933  2py-eta-no2-zdap9882  hythpym-m25thiman2-fo-glyzdap      9934  bzl-dimen-paco-bnsdap9883  chhs-tetras-meto-betaet            9935  deam-25oxman2-fo-betapy9884  2py-m24thizman2-oem-aspibua        9936  2py-tetradi-chexo-betapy9885  pippy-din-5pho-psdab               9937  bimhs-dis-hso-asppha9886  pyr-mepipen2-no2-betadcph          9938  amim-tetras-emo-psdap9887  pippy-m25thiz-napo-betadcph        9939  hythpym-thizs-napo-bphabs9888  npip-eta2s-no1-aspibua             9940  bhs-am2-oem-nbetapy9889  bim-dis-no1-psdab                  9941  thpym-eta-ocho-bhsdap9890  thpym-m25thiz-ocho-bhsdap          9942  bimhs-pipmea-imo-aspaba9891  bim-amo2-no2-thizzdap              9943  piraz-mepipe2-oem-nzdab9892  dhim-n2o2n-meo-betapy              9944  2py-edian2-mes-betapy9893  am4py-eta-cpro-bsdap               9945  menim-24oxman2-5pho-betapy9894  amim-pazi2n-peo-bphabs             9946  bz-25oxman2-mes-betainyl9895  hythpym-m25thiz-hso-csdap          9947  imhs-ams2-eoco-betapy9896  impy-n2o2n-mommo-dfzdap            9948  mam2py-m25thiz-emo-mezphe9897  chhs-amn3-no2-mezphe               9949  2py-edian2-eoco-psdap9898  imhs-pyma2-ocho-csdap              9950  hythpym-dimephmep-emo-aspbzla9899  moegua-mea-napo-glupha             9951  me2py-pazin-no2-psdapee9900  amim-pipmea-chexo-zdabs            9952  bim-edia2-sem-nzdap9901  thpym-amo2-chexo-zdapee            9953  bhs-eta-mes-betapy9902  impy-3diaz-no1-oxal                9954  dpam-m25thiz-pro-glubzla9903  me2py-dis-baeo-bsdap               9955  amthiaz-m24oxman2-mommo-tsdap9904  thpym-pazin-no2-betapy             9956  thpym-amn2-no2-bnsdap9905  mam2py-mepipe2-oem-nbetameph       9957  thpym-diphmem-peo-asppha9906  bimhs-pipmea-oem-glyzdap           9958  bhs-amn2-chexo-bhsdap9907  amthiaz-mea2s-napo-mezphe          9959  4pmhs-am3-oem-nbetapy9908  deam-25thiz-emo-aspibua            9960  pippy-ams2-emo-asppha9909  hythpym-hexas-5amo-psdapee         9961  thpym-edian2-5pho-zdap9910  prhs-trias-meo-mezphe              9962  me2py-mepipen2-5pho-aspibua9911  thpym-amn2-oem-betapy              9963  bim-pazin-no2-bnsdap9912  amim-24thizman2-4pho-bhsdap        9964  amim-pipa-no2-bnsdap9913  impy-m25thiz-chexo-aspbzla         9965  amim-m25thiz-meo-bnsdap9914  2py-amn2-meo-asppha                9966  cl3pyme-24thizman2-oem-aspi-9915  am2py-am3-sem-nzdab                bua9967  bhs-m25thiman2-ocho-aspbzla        10018  nim-24thizman2-ocho-mezphe9968  edothpym-edian2-5amo-bhsdab        10019  me2py-amn3-chexo-zdab9969  ibhs-pyma2-emo-mezphe              10020  emnim-thizs-imo-betapy9970  mam2py-pipmea-mecpo-bhsdab         10021  2py-pazin-meo-zdab9971  bimhs-pipmea-no1-psdab             10022  2py-eta-ocho-betapy9972  bimhs-24thiz-pyo-dfzdap            10023  me2py-dimephmep-pyo-psdapee9973  hythpym-trias-no1-mezphe           10024  pyraz-amn2-mes-bsdap9974  dhim-am2-oem-nbetameph             10025  phpip-mepazin-5pho-psdab9975  impy-din-oem-betainyl              10026  thpym-pentadi-emo-glyzdap9976  npip-hexas-4pho-aspibua            10027  me2py-pazin-cpro-betapy9977  amim-25thizman2-ocho-betaet        10028  bhs-mepipe-eoco-zdab9978  2py-pazin-mes-psdap                10029  cl3pyme-pnymea-mes-ibsdap9979  amim-amo2-fo-bphabs                10030  am2py-diphmem-nmo-bsdap9980  bhs-pazin-no2-betapy               10031  bhs-m25thiz-nmo-zdab9981  imhs-mepipe-mes-psdap              10032  thpym-amn2-meto-bnsdap9982  piraz-mepipe-emo-betapy            10033  thpym-am2-oem-nzdap9983  dmbim-pipmea-5pho-bsdap            10034  mam2py-tetradi-fo-psdap9984  imhs-thizn-no2-zdabs               10035  am-mepazin-eoco-zdabs9985  edothpym-diphmem-men-aspibua       10036  mepip-pazin-emo-zdap9986  dhim-din-fo-bhsdap                 10037  amim-amo2-mes-tsdap9987  me-24thizman2-pro-glyzdap          10038  menim-dis-peo-bphabs9988  pippy-pazin-meo-bnsdap             10039  pippy-trias-men-dfzdap9989  menim-tridi-no1-bsdap              10040  2py-edian2-ocho-mezphe9990  bimhs-thizn-chexo-dfzdap           10041  me2py-3diaz-5pho-psdab9991  piraz-diphmem-men-glubzla          10042  ec-tridi-no1-psdab9992  deam-amn3-chexo-zdab               10043  hythpym-propa2s-mes-betapy9993  bhs-mepipe-oem-psdap               10044  2py-amo2-emo-dfzdap9994  2py-pipmea-no1-zdap                10045  imhs-amn2-5pho-zdap9995  dmam-thizs-nmo-aspbzla             10046  hythpym-mepazin-mes-ppsdap9996  dpam-thizn-mes-betapy              10047  bhs-mepipe-meo-bhsdap9997  bim-amn2-meo-betapy                10048  dmbim-amn2-napo-psdap9998  me-dio-pro-psdap                   10049  bhs-pazin-mes-psdap9999  2py-amn2-napo-betainyl             10050  bim-tetradi-men-betadcph10000  2py-eta-no2-psdap                 10051  bhs-edian2-5pho-bnsdap10001  bhs-eta-meo-psdap                 10052  pippy-dimen-oem-psdap
10002  imhs-pyma2-fo-zdab                10053  amim-dis-oem-zdapee10003  thpym-pazin-no2-bsdap             10054  dmam-mepazin-no1-psdapee10004  piraz-amn2-chexo-bnsdap           10055  hythpym-amn3-meo-zdabs10005  impy-propn-oem-psdab              10056  tolhs-ams2-5pho-bphabs10006  me2py-edia2-sem-nzdap             10057  prhs-dimen-5pho-bnsdap10007  bz-pipa-no2-csdap                 10058  bimhs-pnymea-5pho-betapy10008  nim-pyma2-men-psdap               10059  hythpym-dimephmep-no2-bnsdap10009  hythpym-edian2-5pho-aspibua       10060  piraz-diphmem-imo-aspbzla10010  bim-amn2-oem-psdap                10061  bhs-eta-eoco-bsdap10011  impy-indan2-chexo-bnsdap          10062  dmthpym-pentadi-pheo-bphabs10012  am4py-trias-emo-bhsdap            10063  bzl-tetradi-ocho-glupha10013  dhim-ams2-meto-psdab              10064  phpip-dich-imo-psdab10014  edothpym-propa2s-chexo-           10065  hythpym-trias-pyo-betapy
   bhsdap                            10066  bimhs-mepipe-napo-osdap10015  npip-m25thizman2-no1-aspibua      10067  mam2py-diphmem-emo-glyzdap10016  imhs-25oxman2-5pho-bnsdap         10068  amim-pyma2-ocho-csdap10017  bhs-eta-men-zorn                  10069  thpym-ams2-imo-mezphe10070  thpym-diphmep-nmo-oxal            10121  thpym-mepipe-no1-zdap10071  hythpym-hexadi-daco-bsdap         10122  2pmhs-mepipe2-sem-nzdab10072  piraz-m24thizman2-5pho-zorn       10123  impy-amn2-meteto-betaet10073  thpym-dimephmem-no1-csdap         10124  thpym-pyma2-meteto-betainyl10074  mam2py-amo3-eoco-mezphe           10125  am4py-24thizman2-men-bnsdap10075  impy-eta-5pho-zdab                10126  nim-25thiman2-ocho-aspbzla10076  pippy-diphmep-fo-zdabs            10127  n2py-mepipe-mes-aspibua10077  piraz-dipch-cnmo-bphabs           10128  pippy-m25oxman2-5pho-zdabs10078  dhim-pazin-pro-bsdap              10129  dpam-edia2-sem-nzdap10079  2py-mepipe-5pho-psdab             10130  bimhs-din-napo-asppha10080  edothpym-mepipe-napo-dfzdap       10131  me2py-mepipe-5pho-bphabs10081  chmhs-amn2-cpeo-dfzdap            10132  amthiaz-trias-hso-betainyl10082  bhs-hexadi-daco-zdabs             10133  me2py-25thiman2-chexo-dfzdap10083  amim-25thizman2-ocho-zdap         10134  pippy-dimen-hso-betapy10084  2py-amn2-napo-betadcph            10135  piraz-amn2-5pho-csdap10085  emnim-mepipe2-sem-npsdap          10136  me2py-amo2-napo-bnsdap10086  npip-24thiman2-cno-glyzdap        10137  pippy-am2-sem-nzdap10087  imhs-dimephmep-emo-asppha         10138  imhs-n24thiman-fo-psdap10088  impy-amn2-paco-zdabs              10139  n2py-pipmeo-no1-betadcph10089  deam-pyma2-5amo-bhsdap            10140  dmam-24thizman2-nmo-betaet10090  piraz-tridi-chexo-aspaba          10141  2py-thizn-5pho-dfzdap10091  me2py-m25oxman2-meo-mezphe        10142  pippy-hexadi-fo-bhsdab10092  am2py-edian2-imo-bhsdab           10143  amthiaz-ams2-oem-asppha10093  dmam-pnymea-no2-asppha            10144  emnim-amo2-cpeo-aspibua10094  imhs-edian2-fo-bsdap              10145  2py-pazin-no1-zdab10095  am2py-amo2-no1-zdab               10146  thpym-pazin-oem-bsdap10096  mepip-mepazin-napo-csdap          10147  thpym-eta-meo-bnsdap10097  me-edian2-aco-psdap               10148  pippy-dimephmep-mes-bhsdab10098  2py-edian2-no1-bhsdap             10149  piraz-amo3-no2-zdabs10099  amim-pazin-oeto-glubzla           10150  amim-amn3-fo-zdabs10100  pyraz-am2-sem-nbetabnaphth        10151  mam2py-diphmem-chexo-bhsdab10101  mam2py-pnymea-men-aspbzla         10152  thpym-amn2-mes-betapy10102  dhim-pyma2-no2-aspaba             10153  bim-tetradi-eoco-zdab10103  bim-diphmem-chexo-psdab           10154  2py-dimephmem-meo-psdap10104  impy-dipch-imo-psdab              10155  hythpym-dimephmem-imo-bsdap10105  hythpym-pyma2-men-bhsdab          10156  menim-thizo-ocho-asppha10106  pippy-mepipen2-men-betainyl       10157  dmam-ams3-4pho-bsdap10107  bhs-amn2-mes-psdab                10158  thpym-mepipe-oem-bsdap10108  nmor-thizs-fo-zdap                10159  dhim-m24thizman2-5amo-betaet10109  tolhs-dimen-chexo-dfzdap          10160  dmthpym-m25thiz-men-bhsdab10110  dmam-amn3-napo-bhsdap             10161  bhs-amn2-oem-bhsdap10111  2pmhs-amn2-imo-zdap               10162  2py-pazin-no2-bsdap10112  dmbim-pyma2-5pho-aspibua          10163  hythpym-pipmes-meo-betapy10113  impy-tetradi-mes-glyzdap          10164  prhs-m24oxman2-no2-ppsdap10114  bimhs-pentadi-meo-zdab            10165  piraz-diphmem-no2-betainyl10115  imhs-eta-no1-psdab                10166  bhs-24thiz-men-glupha10116  dhim-dimephmep-nmo-psdab          10167  bim-eta2s-men-psdap10117  fthpym-24thizman2-                10168  2pmhs-diphmep-meto-zdab
   5pho-thizzdap                     10169  amim-mepipe-emo-betadcph10118  bim-dimephmep-eoco-ppsdap         10170  piraz-mepazin-emo-psdap10119  bhs-mepipe-5pho-bsdap             10171  bim-pazin-meo-zdap10120  imhs-pazin-meo-bnsdap             10172  2py-24thiz-cpro-zdap10173  2py-diaz-men-bphabs                10224  mam2py-diphmem-imo-glubzla10174  bim-eta-mes-bnsdap                 10225  bhs-pazin-no1-bnsdap10175  pippy-pyma2-imo-psdap              10226  phpip-3pazin-oem-bsdap10176  bhs-3diaz-imo-glyzdap              10227  dhim-m25thiz-chexo-zdab10177  pippy-thizn-men-glyzdap            10228  pippy-eta-meo-zdab10178  bhs-dimen-5pho-glubzla             10229  2py-pazin-5amo-aspbzla10179  bhs-amn3-5pho-betadcph             10230  dhim-24thizman2-oeto-bphabs10180  dhim-25oxman2-no2-bhsdab           10231  nmhs-thizs-meto-mezphe10181  2py-pazin-oem-bsdap                10232  amim-pentas-nmo-oxal10182  imhs-am2-oem-nbetapy               10233  amim-mepipe2-sem-nzdab10183  bim-mepipen2-fo-bphabs             10234  bhs-pyma2-4amo-ppsdap10184  dpam-24thiz-imo-psdab              10235  npip-dimephmep-pheo-betainyl10185  impy-edian2-4pho-bhsdap            10236  pippy-diphmem-oem-bsdap10186  4pmhs-dimephmem-chexo-bhsdap       10237  pippy-eta-peo-csdap10187  dmthpym-dimephmem-cno-zdab         10238  dhim-tetradi-mes-bnsdap10188  bhs-eta-meo-betapy                 10239  piraz-dimephmem-ocho-bhsdab10189  2py-dis-fo-glubzla                 10240  2pmhs-m24thizman2-4amo-psdab10190  edothpym-pnymea-mecpo-             10241  impy-dimephmep-ocho-dfzdap
   glyzdap                            10242  hythpym-mepipe-men-psdab10191  phpip-pymea-eoco-zdab              10243  pippy-pymea-chexo-aspbzla10192  phpip-edian2-fo-bhsdab             10244  fthpym-m24thizman2-nmo-10193  ppy-mepipe2-sem-nbetabnaphth              betapy10194  hythpym-n2o2n-emo-bhsdab           10245  bhs-amn2-no1-psdab10195  amthiaz-pazin-eoco-zdab            10246  bim-dis-pheo-zdab10196  impy-diphmem-pyo-zdapee            10247  piraz-tetradi-mecpo-aspibua10197  bhs-m25thizman2-pyo-asppha         10248  moegua-mepazin-mmen-aspbzla10198  n2py-pazin-imo-mezphe              10249  gua-diphmem-5amo-mezphe10199  dhim-m24thizman2-oem-bhsdap        10250  bim-24thizman2-ocho-psdab10200  2py-tetradi-meo-bhsdab             10251  emnim-diphmem-fo-psdap10201  bhs-mepipe-ocho-asppha             10252  bim-m25thiz-aco-zdab10202  dmbim-mepazin-emo-aval             10253  2py-mepipe-oem-psdap10203  piraz-amo2-fo-aspibua              10254  thpym-24thizman2-meo-psdap10204  imhs-pazin-mes-bhsdap              10255  dmthpym-amo2-men-bhsdap10205  am2py-dimen-no2-bphabs             10256  gua-dimephmep-mes-betapy10206  thpym-ams2-napo-psdab              10257  dmbim-dimephmep-oeto-psdap10207  emnim-amo3-5pho-csdap              10258  pippy-pazin-nmo-aspibua10208  mam2py-am2-oem-nbetapy             10259  gua-dio-cnmo-zlys10209  bim-dimephmep-ocho-psdap           10260  amthiaz-amn3-cno-mezphe10210  bim-pipa-pyo-zdab                  10261  bz-pazin-mmen-zdab10211  bhs-edian2-oem-betapy              10262  piraz-dis-mes-zdap10212  bz-propn-no1-psdap                 10263  bimhs-pazi2n-pheo-aspibua10213  dmbim-hexas-oeto-aspibua           10264  imhs-pazin-meo-betapy10214  dpam-dis-nmo-csdap                 10265  dhim-amo2-5pho-zdapee10215  tolhs-dimephmem-emo-dfzdap         10266  bim-mepipe-cpro-tsdap10216  2py-edian2-no1-bsdap               10267  bhs-diphmep-eoco-glyzdap10217  imhs-thizs-chexo-bphabs            10268  2py-m24thiz-men-bhsdab10218  ibhs-edia2-sem-nbetameph           10269  fthpym-m24thizman2-chexo-10219  nim-pipmea-eoco-dfzdap                    csdap10220  ppy-24thiz-chexo-aspibua           10270  cl3pyme-dimephmep-4amo-10221  amim-24thiz-chexo-bhsdap                  betadcph10222  bimhs-thizn-imo-aspibua            10271  nim-24thizman2-meto-aspbzla10223  menim-24thizman2-meo-bhsdab        10272  2py-edian2-eoco-zdap10273  dhim-24thiz-emo-glyzdap          10324  thpym-edian2-no2-psdab10274  piraz-pipmeo-mommo-zlys          10325  impy-pipmes-pro-betainyl10275  ibhs-eta-men-aspbzla             10326  moegua-ams2-5amo-bhsdap10276  bimhs-diaz-no2-zdabs             10327  amim-amn2-men-asppha10277  thpym-eta2s-4pho-aspbzla         10328  ibhs-pymea-no1-bhsdab10278  deam-diphmem-mes-bnsdap          10329  imhs-pyma2-men-bhsdab10279  emnim-diphmem-cpro-psdab         10330  amim-24thiz-mes-bhsdap10280  bimhs-25oxman2-cpro-zdap         10331  hythpym-amn2-no2-betadcph10281  bzl-24thiz-chexo-betapy          10332  me-tridi-men-asppha10282  pyr-diphmep-cnmo-aspibua         10333  bzl-thizn-5pho-dfzdap10283  piraz-mepazin-no2-aspbzla        10334  dhim-mepazin-emo-bnsdap10284  pippy-trias-mmen-csdap           10335  bhs-eta-ocho-psdap10285  pippy-edian2-5amo-psdap          10336  im-amo2-eoco-csdap10286  piraz-m25thiz-5pho-psdab         10337  dmthpym-m24thizman2-10287  dmbim-pipmea-ocho-dfzdap                5pho-zdap10288  amthiaz-am2-sem-nbetapy          10338  thpym-24thizman2-no2-psdab10289  dmbim-hexadi-ocho-betadcph       10339  thpym-n24thiman-aco-psdab10290  n2py-dipch-mes-aspibua           10340  2py-indan2-5pho-bnsdap10291  imhs-diphmep-cnmo-aspbzla        10341  piraz-pipmes-chexo-betainyl10292  pippy-indan2-chexo-psdab         10342  bimhs-eta-meo-bsdap10293  hythpym-thizn-pro-betadcph       10343  bhs-trias-emo-bphabs10294  impy-mea2s-men-bnsdap            10344  bim-pazin-meo-betapy10295  impy-diphmem-4pho-bhsdab         10345  pippy-pazin-mes-betadcph10296  impy-m25oxman2-ocho-psdap        10346  mam2py-dis-fo-bhsdap10297  chhs-pipa-emo-aspbzla            10347  piraz-thizs-emo-tsdap10298  cl3pyme-diphmep-cno-zdab         10348  fthpym-24thizman2-eoco-psdap10299  nmor-pnymea-5pho-asppha          10349  me-m25thizman2-pyo-psdab10300  impy-am3-sem-npsdap              10350  pippy-edian2-cno-csdap10301  cl3pyme-dimephmep-meteto-        10351  me2py-din-4amo-zdabs
   aspaba                           10352  mam2py-pentas-5pho-dfzdap10302  dhim-m24thizman2-ocho-zdabs      10353  bim-mepipe-eoco-zdab10303  amim-pyma2-napo-betadcph         10354  2py-tridi-5pho-zdapee10304  pippy-eta-nmo-aspibua            10355  mam2py-ams2-no1-betapy10305  gua-am2-oem-npsdap               10356  moegua-n2nme2n-baeo-glyzdap10306  bimhs-24thiz-napo-dfzdap         10357  npip-pipmea-no1-psdab10307  prhs-24thizman2-oem-zorn         10358  amim-diphmep-imo-glyzdap10308  pippy-mepazin-4amo-glupha        10359  mam2py-dimephmep-emo-psdab10309  2pmhs-din-fo-aspibua             10360  piraz-mepipe2-sem-nbetameph10310  2py-amn2-no2-zdab                10361  bim-pyma2-cnmo-aspbzla10311  bhs-pnymea-chexo-bhsdap          10362  am2py-pipmea-4amo-aspbzla10312  pippy-24thiz-mes-zlys            10363  bhs-24thizman2-oem-csdap10313  dmthpym-pymea-napo-bhsdab        10364  bimhs-thizn-men-zdabs10314  2py-din-5amo-zdab                10365  bim-pymea-5amo-betaet10315  bimhs-am3-sem-nbetameph          10366  amim-mea2s-mes-psdab10316  bim-mepazin-chexo-psdap          10367  edothpym-edian2-baeo-10317  bhs-thizs-oem-glyzdap                   betadcph10318  bzl-pazin-mes-bsdap              10368  bim-m25thiman2-ocho-oxal10319  hythpym-dimen-5pho-thizzdap      10369  bim-mepipe-no1-zdap10320  amthiaz-pipa-nmo-bhsdap          10370  bz-amo2-no2-zdap10321  nmor-eta-imo-bsdap               10371  amim-thizs-ocho-asppha10322  am2py-thizo-oem-osdap            10372  4pmhs-dis-no2-asppha10323  phpip-amn2-no2-dfzdap            10373  am2py-pentas-oem-bhsdab10374  hythpym-diphmep-mmen-mezphe        10426  2py-mea2s-imo-aspbzla10375  2py-trias-fo-betapy                10427  bim-pazin-no2-psdap10376  impy-diphmem-emo-osdap             10428  bim-eta-mes-psdab10377  dmbim-mepipen2-ocho-asppha         10429  am2py-thizn-emo-bhsdap10378  2py-amn2-no2-psdab                 10430  2py-mepazin-5pho-psdap10379  imhs-amn2-5pho-asppha              10431  imhs-dimephmep-oem-zdab10380  me2py-dimephmem-ocho-glyzdap       10432  bhs-ams2-men-betapy10381  impy-hexas-fo-zdabs                10433  n2py-am2-oem-npsdap10382  thpym-pipa-emo-aspibua             10434  z-24thiz-5pho-csdap10383  imhs-diphmem-imo-psdab             10435  nmhs-dimen-daco-zlys10384  imhs-tridi-ocho-asppha             10436  menim-diphmep-mes-bphabs10385  mam2py-25oxman2-mes-psdap          10437  dhim-amn2-imo-dfzdap10386  nmhs-ams2-5pho-aspbzla             10438  am2py-pipa-mes-betapy10387  bz-m24thiman2-5pho-betadcph        10439  ppy-trias-no2-aspibua10388  bimhs-mepipen2-cpro-zdabs          10440  pyr-am3diaz-fo-bphabs10389  im-amo2-emo-zdab                   10441  deam-dimen-mes-dfzdap10390  am2py-dis-eoco-asppha              10442  n2py-pyma2-no2-bhsdab10391  2py-amn2-mes-zdab                  10443  dhim-dimephmem-meo-aspibua10392  deam-dis-imo-mezphe                10444  bim-eta-eoco-bsdap10393  bim-edian2-meo-bsdap               10445  phpip-25oxman2-men-asppha10394  impy-tridi-5amo-bsdap              10446  pippy-eta-meteto-zdab10395  dhim-m24thiman2-oem-betapy         10447  imhs-m24thizman2-no2-bhsdab10396  im-tridi-emo-zdapee                10448  2py-edia2-oem-nbetabnaphth10397  bhs-pazin-5pho-bsdap               10449  bhs-mepazin-fo-dfzdap10398  thpym-amn2-ocho-psdab              10450  bhs-tetradi-5pho-zdabs10399  phhs-m24thiz-napo-zdabs            10451  impy-m24thizman2-5amo-bphabs10400  pippy-hexadi-men-bnsdap            10452  nim-pnymea-5pho-aspbzla10401  am2py-tridi-chexo-bsdap            10453  bim-eta-no2-zdap10402  imhs-dimephmem-eoco-zdap           10454  dhim-mepipe-oeto-aspibua10403  bhs-edian2-oem-bsdap               10455  n2py-tridi-no2-zdap10404  hythpym-propa2s-cnmo-zdabs         10456  imhs-pymea-mes-bhsdap10405  amim-trias-chexo-asppha            10457  mam2py-dimen-chexo-betapy10406  ibhs-pnymea-napo-asppha            10458  prhs-pazin-oem-asppha10407  imhs-eta-no2-csdap                 10459  bhs-pazin-no1-psdap10408  imhs-pipa-pheo-bhsdab              10460  amthiaz-ams2-men-bsdap10409  me2py-m25thiz-men-mezphe           10461  2py-thizn-5amo-mezphe10410  menim-diphmep-5amo-psdap           10462  pippy-mepipe-men-bnsdap10411  chmhs-n2nme2n-meteto-aspbzla       10463  bhs-thizn-oem-psdap10412  impy-m24oxman2-napo-aval           10464  bhs-m24oxman2-men-betadcph10413  dhim-dis-eoco-glyzdap              10465  am2py-pipmea-mecpo-bhsdab10414  mam2py-pazin-5pho-bhsdap           10466  bimhs-propa2s-mes-zdapee10415  pyr-ams2-pyo-betaet                10467  bz-trias-men-psdab10416  bimhs-m25thiz-fo-dfzdap            10468  deam-24thizman2-napo-glupha10417  moegua-24thiz-ocho-asppha          10469  bhs-dimephmep-mes-aspbzla10418  chmhs-24thiman2-mes-bhsdab         10470  pippy-pazin-5pho-csdap10419  impy-diphmem-men-osdap             10471  prhs-dimen-no1-mezphe10420  impy-24thiz-emo-glyzdap            10472  dhim-mepipe-5pho-betainyl10421  imhs-mepipen2-ocho-dfzdap          10473  pippy-dis-ocho-zdab10422  am2py-amn3-5pho-asppha             10474  bimhs-pipa-mes-csdap10423  menim-amn3-napo-mezphe             10475  impy-tridi-ocho-bhsdap10424  bim-mepipe-eoco-bnsdap             10476  hythpym-thizo-cno-zdabs10425  amim-din-fo-aspibua                10477  dhim-3pazin-nmo-betapy10478  piraz-dimen-fo-glyzdap            10528  im-tetradi-mmen-dfzdap10479  nim-mepipe2-sem-npsdap            10529  fthpym-pyma2-ocho-bphabs10480  hythpym-24thizman2-cnmo-          10530  imhs-amn2-no1-zdab
   zdapee                            10531  bimhs-25oxman2-oem-dfzdap10481  dmam-amn2-fo-dfzdap               10532  me2py-mepipe2-oem-nzdap10482  piraz-thizn-eoco-betadcph         10533  am2py-thizn-no1-aspbzla10483  mam2py-hexas-eoco-zdabs           10534  ppy-eta2s-cpro-bhsdap10484  dhim-tridi-eoco-bhsdab            10535  me2py-24thizman2-oem-zdabs10485  hythpym-pnymea-emo-csdap          10536  impy-mepipe-meteto-psdab10486  mam2py-m25thiz-napo-betapy        10537  am2py-m24thiz-mes-bnsdap10487  moegua-edia2-sem-nbetapy          10538  pippy-dis-mes-mezphe10488  dhim-pymea-nmo-bphabs             10539  2py-pazin-eoco-psdap10489  im-amn2-imo-glubzla               10540  thpym-eta-fo-zdap10490  gua-ams2-fo-dfzdap                10541  mam2py-mea2s-nmo-bnsdap10491  pippy-amn2-meo-betadcph           10542  2py-pazin-emo-csdap10492  bhs-dio-cnmo-bhsdab               10543  im-pyma2-meto-dfzdap10493  2py-eta-meo-bhsdap                10544  imhs-dimephmep-ocho-bhsdab10494  phhs-mea-fo-aval                  10545  bim-mepipe-no2-bhsdab10495  2py-dimen-oem-betapy              10546  bim-amn2-eoco-betapy10496  nmhs-mepazin-fo-psdap             10547  cl3pyme-dimen-no1-psdapee10497  edothpym-3pazin-no2-csdap         10548  ppy-dich-no2-csdap10498  me2py-tetras-no2-asppha           10549  bz-ms-imo-bhsdap10499  thpym-pyma2-hso-glyzdap           10550  ppy-dis-pyo-psdap10500  mam2py-eta-meto-psdab             10551  piraz-diaz-cno-glyzdap10501  ec-ams3-5amo-bhsdap               10552  pippy-trias-mmen-zdap10502  2py-pazin-mes-psdab               10553  dpam-edia2-sem-nzdab10503  thpym-edian2-meo-bnsdap           10554  nmor-24thiman-meo-bnsdap10504  me-mepipen2-ocho-osdap            10555  bimhs-trias-mes-zdabs10505  bim-diaz-cno-zdabs                10556  npip-ams2-meo-glyzdap10506  amim-tetras-no1-dfzdap            10557  me2py-tetradi-mes-bnsdap10507  emnim-dimephmem-ocho-psdab        10558  cl3pyme-edian2-eoco-psdap10508  deam-dimen-cpro-psdapee           10559  bimhs-pnymea-chexo-tsdap10509  bhs-mepazin-mecpo-zorn            10560  nmhs-dimephmem-napo-mezphe10510  am2py-pentas-5pho-glupha          10561  bim-ams2-oem-psdap10511  ppy-din-fo-betaet                 10562  bim-amn2-ocho-bnsdap10512  impy-mepipe-no1-glyzdap           10563  thpym-dis-mes-bphabs10513  pippy-m24thizman2-4amo-           10564  hythpym-ms-mmen-aval
   aspbzla                           10565  edothpym-diphmep-4pho-psdab10514  bimhs-dis-oem-aspbzla             10566  am2py-thizn-men-dfzdap10515  2py-edian2-5pho-zdab              10567  dmthpym-pazi2n-imo-asppha10516  cl3pyme-tridi-meto-betainyl       10568  hythpym-dimen-men-ppsdap10517  piraz-25oxman2-eoco-betaet        10569  nmor-m24thizman2-ocho-bhsdab10518  me2py-am2-oem-nbetapy             10570  me-mea-aco-zdap10519  dhim-pymea-5pho-zlys              10571  dmbim-propa2s-no1-zdabs10520  thpym-trias-meteto-zdabs          10572  me2py-mepazin-fo-bphabs10521  thpym-mepipe-5pho-bhsdap          10573  thpym-eta2s-mes-aspibua10522  me2py-diphmep-4pho-psdap          10574  cl3pyme-amo2-chexo-betadcph10523  amim-butn-chexo-ibsdap            10575  amim-pyma2-eoco-zdabs10524  nmor-dimephmep-meo-osdap          10576  impy-dis-oeto-bsdap10525  2py-edian2-ocho-zdab              10577  hythpym-amo2-ocho-ppsdap10526  2py-diphmep-ocho-mezphe           10578  deam-pipa-eoco-zdapee10527  chmhs-ams2-napo-aspbzla           10579  z-amn2-5pho-psdap10580  bimhs-24thiz-no1-bphabs          10630  deam-tetradi-paco-psdab10581  2py-dimen-no2-glubzla            10631  bim-pnymea-emo-betainyl10582  amim-m25thiz-5pho-betapy         10632  thpym-dimephmep-pro-thizzdap10583  piraz-dimephmem-hso-zdap         10633  imhs-pyma2-no1-aspibua10584  bhs-24thiz-baeo-zdap             10634  amthiaz-amo2-pheo-glyzdap10585  impy-24oxman2-emo-betainyl       10635  thpym-dimephmem-mecpo-csdap10586  dmthpym-pymea-meto-aspibua       10636  mam2py-pyma2-cnmo-bsdap10587  piraz-m24oxman2-imo-dfzdap       10637  am2py-24oxman2-5amo-bphabs10588  amthiaz-eta-5pho-glupha          10638  amim-tetras-5amo-mezphe10589  ibhs-pazi2n-fo-aspbzla           10639  mam2py-pymea-imo-betadcph10590  imhs-diphmem-chexo-zdab          10640  pyrhs-24thiz-5pho-psdap10591  pyraz-hexadi-oem-betaet          10641  ppy-m24thizman2-fo-csdap10592  thpym-tetradi-mes-betainyl       10642  bhs-edian2-ocho-betapy10593  mam2py-24thiz-mes-betadcph       10643  mam2py-dis-napo-zdabs10594  impy-pipa-eoco-betadcph          10644  pyrhs-ams3-napo-betadcph10595  imhs-propn-5pho-asppha           10645  bhs-pazin-oem-psdab10596  deam-eta-chexo-asppha            10646  amim-pyma2-5pho-aspibua10597  bimhs-mepazin-oem-bhsdap         10647  impy-pymea-peo-zorn10598  imhs-24thizman2-no2-zdap         10648  nmor-ams2-chexo-bhsdab10599  edothpym-pyma2-cpeo-zdap         10649  hythpym-tridi-5pho-zdab10600  bimhs-eta-oeto-bphabs            10650  pippy-diphmem-pheo-betainyl10601  2py-diaz-oem-asppha              10651  am2py-dis-hso-dfzdap10602  pippy-25oxman2-cno-tsdap         10652  am2py-pipmea-emo-bnsdap10603  cl3pyme-25oxman2-oeto-           10653  ibhs-eta-fo-glubzla
   glyzdap                          10654  pyraz-amo2-mes-zdap10604  bim-tetradi-cpeo-zdabs           10655  nim-m24thiman2-meteto-psdap10605  pyr-am2-sem-nbetapy              10656  imhs-amn2-meo-psdab10606  menim-24thiman-mes-glyzdap       10657  imhs-amn3-men-betainyl10607  impy-2pazin-5pho-csdap           10658  me2py-am3-oem-nbetameph10608  bim-m24oxman2-napo-asppha        10659  bhs-edian2-5pho-zdap10609  dhim-tetradi-no1-zorn            10660  bim-24thiman2-mommo-glupha10610  prhs-ams3-meo-bnsdap             10661  edothpym-pnymea-no1-aspibua10611  mam2py-dimephmep-ocho-bhsdap     10662  menim-edian2-meo-bhsdab10612  impy-25oxman2-meo-zdab           10663  bhs-amo3-cno-zdab10613  am2py-dimephmem-pyo-betainyl     10664  impy-edian2-ocho-psdap10614  pippy-pipmea-napo-zdap           10665  bim-pymea-5pho-betapy10615  me2py-eta-fo-osdap               10666  2pmhs-pazin-pheo-asppha10616  mam2py-24oxman2-meo-bhsdab       10667  dhim-dis-mes-zdap10617  impy-din-baeo-zdap               10668  bhs-m24thizman2-5amo-bsdap10618  npip-mepipe-aco-bnsdap           10669  impy-edia2-oem-nbeta34-10619  pyrhs-pnymea-men-osdap                  dimeoph10620  amthiaz-tridi-fo-mezphe          10670  bhs-m25thiz-eoco-tsdap10621  amim-pymea-no1-oxal              10671  hythpym-ams2-no1-zdabs10622  impy-tetradi-no1-ppsdap          10672  me2py-dis-imo-mezphe10623  n2py-24thizman2-5pho-            10673  me2py-n2nme2n-no2-bsdap
   betainyl                         10674  bhs-dimephmep-pyo-bnsdap10624  2py-din-chexo-bnsdap             10675  pippy-pazin-mommo-asppha10625  nmhs-pipa-emo-glupha             10676  bim-amn2-eoco-zdab10626  mam2py-dimephmep-no2-bphabs      10677  chhs-ams2-baeo-bnsdap10627  nmor-m24thizman2-ocho-mezphe     10678  imhs-edian2-no1-psdap10628  thpym-pazin-oem-bhsdap           10679  thpym-eta-5pho-psdap10629  bim-pazin-meo-bhsdap             10680  chhs-pazin-5amo-mezphe10681  dmam-amo2-men-bnsdap              10732  2py-mepipe-oem-betapy10682  im-diaz-fo-zdab                   10733  imhs-mepipe-ocho-bhsdap10683  imhs-eta-no2-zdap                 10734  deam-amo2-5pho-zdap10684  thpym-eta-eoco-zdab               10735  thpym-tridi-men-csdap10685  ec-24thizman2-eoco-zdab           10736  mam2py-pnymea-oem-psdab10686  dhim-mea-oem-zdab                 10737  imhs-diphmep-mes-zdab10687  am2py-diphmem-mes-dfzdap          10738  gua-24thiman-chexo-aspbzla10688  bhs-dimephmep-chexo-dfzdap        10739  2py-n2nme2n-eoco-zdabs10689  im-24thizman2-men-bphabs          10740  bhs-eta2s-eoco-glyzdap10690  thpym-mepipe-ocho-psdab           10741  ibhs-24thizman2-meo-psdapee10691  thpym-amn2-paco-bphabs            10742  morhs-amo2-men-bhsdab10692  thpym-pazin-no2-bnsdap            10743  impy-thizn-men-csdap10693  nmhs-pipmea-pheo-aspbzla          10744  hythpym-pyma2-hso-aspaba10694  hythpym-diphmep-fo-bnsdap         10745  2pmhs-pazi2n-no1-betaet10695  ibhs-diphmep-5amo-aspbzla         10746  dhim-25oxman2-meo-betadcph10696  am2py-edia2-oem-nbetapy           10747  2pmhs-pazi2n-4pho-zdabs10697  bhs-m24thiz-imo-betainyl          10748  imhs-24thizman2-5amo-bphabs10698  amthiaz-edian2-5amo-psdap         10749  ibhs-amo2-4pho-zlys10699  me-pnymea-oem-bhsdab              10750  fthpym-pipa-oem-bhsdab10700  prhs-tridi-cpro-bhsdab            10751  mam2py-mepipen2-emo-aspbzla10701  bim-mepipe-hso-aspibua            10752  pyr-dimephmep-fo-aspbzla10702  imhs-edian2-meo-psdap             10753  me2py-diphmep-5amo-thizzdap10703  imhs-mepipe-mes-bsdap             10754  tolhs-mepazin-meto-aspibua10704  mam2py-24thiz-ocho-zdab           10755  thpym-pyma2-emo-aspibua10705  2py-edian2-no1-bnsdap             10756  pyraz-m24oxman2-oem-mezphe10706  amthiaz-amo2-chexo-dfzdap         10757  moegua-mepipen2-no2-bhsdap10707  tolhs-mepipen2-mecpo-asppha       10758  bimhs-ams2-men-zdap10708  hythpym-din-ocho-bnsdap           10759  im-pnymea-emo-zdab10709  bhs-n2o2n-ocho-psdap              10760  bhs-am2-oem-nbetabnaphth10710  bim-am3-sem-nzdap                 10761  deam-eta-5pho-aspibua10711  2py-amo2-mes-zdab                 10762  bim-m24thiz-men-mezphe10712  thpym-mepipen2-4amo-psdab         10763  dmthpym-n2o2n-ocho-bhsdap10713  bhs-24thizman2-no1-aspbzla        10764  impy-pyma2-pheo-glubzla10714  me2py-dipch-mmen-ibsdap           10765  pyraz-ms-fo-zdabs10715  dhim-pnymea-cpro-psdap            10766  am2py-dimephmem-nmo-zdabs10716  menim-24thizman2-5amo-            10767  pyr-tetradi-eoco-bphabs
   aspibua                           10768  impy-din-cpro-bhsdab10717  bim-pazin-no2-psdab               10769  pyr-dimephmep-chexo-glupha10718  mam2py-dimephmem-napo-zdabs       10770  mam2py-mepipe-ocho-betadcph10719  dmbim-ams2-imo-psdap              10771  phpip-m25oxman2-men-betadcph10720  am2py-diphmem-5pho-zdapee         10772  mepip-indan2-5amo-asppha10721  pippy-tetradi-chexo-mezphe        10773  thpym-pipmea-meo-asppha10722  thpym-edian2-no1-betapy           10774  pippy-dimen-eoco-asppha10723  pyrhs-pazin-chexo-asppha          10775  chmhs-amo2-no1-osdap10724  piraz-mepazin-napo-bsdap          10776  2py-eta-mes-zdab10725  amim-pazin-no1-zdabs              10777  bim-amn2-mes-bhsdap10726  hythpym-24thiz-imo-dfzdap         10778  morhs-amn2-pyo-bhsdap10727  nim-ams3-5amo-betapy              10779  bhs-m24oxman2-oem-zdap10728  thpym-mepipe-mes-bnsdap           10780  dmam-mea-chexo-psdap10729  me-24thiz-mmen-mezphe             10781  dhim-mea-meteto-ppsdap10730  me2py-pyma2-5pho-aspbzla          10782  imhs-pymea-imo-betadcph10731  am2py-dimen-oem-zdap              10783  mam2py-mepipe2-sem-nzdap10784  piraz-diphmep-eoco-glyzdap        10834  2py-pazin-oem-psdab10785  am-dimephmem-5pho-aspbzla         10835  cl3pyme-diphmep-napo-tsdap10786  dpam-24thizman2-ocho-bnsdap       10836  im-pazin-pheo-betadcph10787  2py-tetras-cpro-bphabs            10837  thpym-pazin-hso-mezphe10788  imhs-pazin-no1-zdap               10838  imhs-dimephmem-pyo-dfzdap10789  mam2py-dimeph-mem-chexo-zlys      10839  hythpym-m25thiz-imo-glyzdap10790  me2py-pazin-emo-aspibua           10840  morhs-am3diaz-meo-asppha10791  thpym-indan2-aco-zdabs            10841  amthiaz-dio-meto-csdap10792  me2py-trias-no2-mezphe            10842  amim-diphmep-imo-psdapee10793  morhs-mepazin-ocho-dfzdap         10843  imhs-mea-chexo-psdap10794  dhim-dio-no2-aspibua              10844  dhim-mepazin-5pho-aspibua10795  bim-amo2-ocho-zdabs               10845  tolhs-24thiz-no1-betadcph10796  imhs-m24oxman2-meo-osdap          10846  amim-edian2-fo-bphabs10797  piraz-ams2-eoco-ibsdap            10847  mam2py-mepipe2-sem-nzdab10798  thpym-diphmep-cpeo-betadcph       10848  pippy-m25thiz-mommo-psdap10799  piraz-dimephmep-meteto-           10849  mam2py-pentas-5amo-psdap
   glyzdap                           10850  piraz-propn-5pho-dfzdap10800  pippy-pentadi-emo-bnsdap          10851  imhs-diphmep-oem-zdabs10801  bhs-eta-4amo-bnsdap               10852  mam2py-dimen-oem-zdab10802  bimhs-tridi-meo-bsdap             10853  bzl-tridi-fo-bhsdab10803  thpym-25oxman2-meteto-psdab       10854  dmthpym-pymea-men-betainyl10804  bim-ams2-no2-aspbzla              10855  2py-am3-oem-nbetameph10805  bhs-pazin-oem-bnsdap              10856  bimhs-pymea-mes-aspibua10806  bhs-amn2-mes-betapy               10857  amim-m24thiz-oem-psdap10807  imhs-amn2-eoco-betapy             10858  hythpym-propn-meo-bhsdap10808  am2py-edian2-pro-psdab            10859  2py-edian2-5pho-psdab10809  menim-tetradi-cpro-aspibua        10860  thpym-eta-ocho-bsdap10810  impy-m25thiz-4amo-aspaba          10861  imhs-diphmep-napo-psdab10811  bimhs-24thiz-ocho-bnsdap          10862  me2py-thizn-chexo-zdabs10812  edothpym-amn2-pyo-bsdap           10863  thpym-dio-men-glubzla10813  me2py-pazin-mommo-zdap            10864  imhs-amn2-no2-zdap10814  hythpym-25oxman2-chexo-           10865  morhs-pipmea-4amo-aval
   mezphe                            10866  mam2py-edia2-oem-nbeta34-10815  n2py-25oxman2-men-zdabs                  dimeoph10816  pyr-m24thizman2-imo-betadcph      10867  ec-mepipen2-napo-bnsdap10817  dhim-am3-oem-nbetameph            10868  deam-edian2-5amo-bhsdab10818  tolhs-dimen-mes-aval              10869  2py-mepipe-meo-bnsdap10819  bimhs-m25thiz-ocho-asppha         10870  2py-tridi-5pho-glubzla10820  am2py-mepipe2-oem-npsdap          10871  mam2py-amn3-5amo-aspibua10821  amim-edian2-5amo-glyzdap          10872  bim-pyma2-napo-zdab10822  dhim-dimephmem-men-psdab          10873  am2py-pazin-mes-bnsdap10823  dhim-edian2-5amo-bsdap            10874  dpam-indan2-cnmo-aspibua10824  pippy-am2-sem-nzdap               10875  nim-24thizman2-chexo-bphabs10825  am2py-diphmep-fo-mezphe           10876  amim-pymea-aco-bhsdap10826  thpym-mepipe-mmen-betapy          10877  hythpym-dis-no1-betapy10827  phpip-mepazin-no1-bphabs          10878  impy-pyma2-emo-bphabs10828  2py-eta-oem-zdab                  10879  2py-edian2-5pho-bsdap10829  mam2py-tetras-meo-betapy          10880  amthiaz-mea2s-5pho-mezphe10830  pippy-diphmep-oem-bphabs          10881  impy-25oxman2-chexo-zdabs10831  am2py-mepipen2-5amo-bsdap         10882  bimhs-mepipe2-sem-nzdap10832  npip-ams2-eoco-zdap               10883  imhs-pnymea-no1-betapy10833  pyraz-m25thiz-5amo-bsdap          10884  2py-pipa-mes-betapy10885  pyraz-25oxman2-mecpo-mezphe       10936  im-amn3-cpeo-bhsdab10886  tolhs-am2-oem-nbetabnaphth        10937  impy-am3-sem-nzdap10887  bhs-diphmep-meto-bsdap            10938  bhs-amo3-pro-psdap10888  hythpym-amn3-chexo-bnsdap         10939  ec-pentas-chexo-aspibua10889  bim-edian2-5pho-psdab             10940  2py-mepipe-mes-bhsdap10890  bim-25oxman2-fo-psdab             10941  me2py-thizn-imo-bhsdap10891  imhs-pipa-cpeo-psdap              10942  4pmhs-edian2-ocho-bnsdap10892  thpym-mepipe-oem-betapy           10943  dmbim-am3diaz-no1-bphabs10893  me2py-24thizman2-paco-bsdap       10944  mam2py-3diaz-no2-bphabs10894  edothpym-pentadi-baeo-psdap       10945  emnim-24thizman2-fo-zdap10895  gua-pipmeo-mommo-zdabs            10946  bim-mepipe-eoco-bsdap10896  chmhs-props-5amo-bphabs           10947  bimhs-mepipe-emo-thizzdap10897  bhs-tridi-oeto-thizzdap           10948  piraz-trias-peo-asppha10898  im-tridi-men-psdab                10949  dhim-3pazin-imo-mezphe10899  2py-mepipe-ocho-psdab             10950  me2py-amn3-baeo-bhsdap10900  pyraz-tridi-eoco-zdab             10951  am4py-pazin-emo-zdap10901  hythpym-diphmep-emo-psdap         10952  bhs-amn2-no1-bsdap10902  nmor-pazin-cpeo-aspaba            10953  imhs-mepipe-mes-betapy10903  bzl-eta-meteto-asppha             10954  am4py-din-mes-betaet10904  tolhs-pipmeo-mes-zdab             10955  bhs-eta-oem-betainyl10905  bimhs-dimen-oem-asppha            10956  dhim-dis-4amo-zdabs10906  thpym-pnymea-no1-zdabs            10957  phpip-dimephmem-cnmo-psdab10907  bimhs-mepipen2-baeo-tsdap         10958  2py-tetradi-5amo-tsdap10908  me2py-mepipen2-ocho-betadcph      10959  bim-props-men-zdab10909  2py-eta-eoco-zdab                 10960  me2py-pentas-emo-bsdap10910  pippy-dimen-men-psdapee           10961  mepip-am3diaz-meteto-bhsdap10911  imhs-25oxman2-napo-zdabs          10962  dmam-dipch-mmen-bphabs10912  hythpym-m24thizman2-4amo-         10963  hythpym-eta-oem-psdap
   asppha                            10964  pyrhs-mepipe2-sem-nbeta34-10913  imhs-eta-no2-zdab                        dimeoph10914  am4py-mepipen2-ocho-zdabs         10965  bz-mepipe2-sem-nbetameph10915  thpym-3diaz-5amo-bsdap            10966  fthpym-m24thizman2-eoco-10916  piraz-amn2-oem-betadcph                  betapy10917  n2py-dimephmep-no1-betainyl       10967  nmor-din-no2-betainyl10918  menim-n2o2n-baeo-betadcph         10968  nmhs-diphmep-5pho-zdab10919  n2py-tridi-no2-ppsdap             10969  pippy-dimen-napo-aval10920  me2py-trias-5pho-betadcph         10970  pyrhs-am3-sem-nbetameph10921  2py-m25oxman2-no1-bhsdap          10971  bz-din-5amo-bnsdap10922  dhim-ams2-eoco-asppha             10972  pippy-3pazin-emo-bsdap10923  pippy-edian2-oem-bsdap            10973  bimhs-pazin-5pho-mezphe10924  imhs-amn3-pheo-bphabs             10974  dmbim-amn2-napo-mezphe10925  gua-dimephmep-mommo-bphabs        10975  bim-trias-emo-aspbzla10926  piraz-edian2-daco-tsdap           10976  piraz-amo2-emo-betadcph10927  emnim-amn2-no2-glyzdap            10977  npip-diphmep-no2-zdabs10928  mepip-24thiz-4amo-bsdap           10978  bim-thizs-napo-dfzdap10929  2py-amn3-5pho-bsdap               10979  me2py-trias-imo-glyzdap10930  bimhs-pipa-cpro-aspibua           10980  pyraz-25oxman2-napo-bnsdap10931  chmhs-dimephmep-meo-bnsdap        10981  chhs-dis-eoco-betadcph10932  hythpym-n2o2n-imo-betainyl        10982  imhs-amn2-meo-zdab10933  bimhs-am2-sem-nzdap               10983  imhs-ams2-5amo-bsdap10934  pippy-ams3-no2-asppha             10984  mam2py-amn2-napo-betadcph10935  hythpym-ams2-5amo-csdap           10985  mam2py-n24thiman-no2-aspibua10986  am4py-pymea-aco-zdap              11038  mam2py-mepipen2-napo-psdap10987  mam2py-eta-chexo-bhsdap           11039  bhs-eta-5pho-zdab10988  2py-din-meo-thizzdap              11040  me-tetradi-5pho-zdab10989  thpym-pazin-fo-bhsdab             11041  ec-24thiz-napo-bsdap10990  morhs-pnymea-emo-betadcph         11042  imhs-ams2-no2-glyzdap10991  fthpym-eta-hso-betadcph           11043  edothpym-25oxman2-10992  dpam-pipa-oem-tsdap                      napo-bhsdap10993  2pmhs-pipmes-men-zlys             11044  imhs-eta-eoco-psdab10994  pippy-tridi-napo-mezphe           11045  imhs-dimephmep-mes-zdabs10995  z-edian2-eoco-betadcph            11046  bim-pymea-mes-glyzdap10996  imhs-m25oxman2-5pho-betapy        11047  bhs-amo2-men-ppsdap10997  pippy-amo2-pro-csdap              11048  bim-mepipen2-fo-glupha10998  bimhs-amn2-napo-betapy            11049  menim-amo3-napo-betadcph10999  am4py-m24thiman2-5amo-zlys        11050  bhs-edian2-no1-bhsdap11000  morhs-24thizman2-meo-asppha       11051  amim-diphmep-no1-bhsdab11001  4pmhs-am3-sem-nbetapy             11052  bhs-edian2-napo-zdap11002  mepip-m25thiz-ocho-bhsdap         11053  am2py-pentas-men-psdap11003  impy-propn-mmen-zdab              11054  thpym-eta-oem-psdap11004  imhs-eta-men-bhsdap               11055  fthpym-pazin-emo-csdap11005  ec-edian2-nmo-dfzdap              11056  imhs-pipa-chexo-betapy11006  pippy-dimephmem-ocho-bnsdap       11057  pyraz-pnymea-mes-aspbzla11007  prhs-mepipen2-fo-dfzdap           11058  mam2py-pazin-meto-mezphe11008  thpym-pipa-aco-bsdap              11059  ec-24thiman2-emo-bphabs11009  pippy-trias-5pho-aspbzla          11060  bhs-amn2-no2-psdap11010  dhim-mepipe-eoco-aval             11061  ibhs-m24thizman2-meo-bhsdap11011  pippy-dimen-eoco-bnsdap           11062  imhs-eta-eoco-zdab11012  mam2py-tridi-eoco-dfzdap          11063  bhs-mepipe-5pho-betapy11013  pyraz-pyma2-imo-psdab             11064  impy-am3-oem-nbeta34dimeoph11014  bimhs-am3-sem-nbetapy             11065  am2py-diphmep-cpro-zdap11015  ec-trias-ocho-bphabs              11066  me2py-n2o2n-fo-psdab11016  bimhs-24thiz-fo-aspbzla           11067  piraz-25oxman2-meo-bnsdap11017  menim-dis-oem-aspbzla             11068  morhs-25thizman2-nmo-asppha11018  tolhs-thizs-ocho-bhsdab           11069  pyraz-24thiz-5pho-zdap11019  imhs-pymea-no2-aspaba             11070  pyrhs-em2-sem-nbetameph11020  dhim-pazin-men-bhsdab             11071  prhs-edian2-emo-glyzdap11021  dhim-amn3-eoco-asppha             11072  dmthpym-pipmeo-mes-betapy11022  am2py-edian2-meo-psdab            11073  piraz-24thiz-5pho-bnsdap11023  pippy-pipmea-no1-psdab            11074  pippy-tetradi-oem-mezphe11024  bimhs-mepipen2-emo-zdap           11075  deam-am2-sem-nzdab11025  me2py-ams3-cnmo-aspaba            11076  bhs-mepipe-mecpo-bnsdap11026  thpym-eta-5pho-bnsdap             11077  amim-2pazin-baeo-bhsdap11027  nmor-pipa-oem-mezphe              11078  n2py-eta-emo-betainyl11028  fthpym-amn2-cpeo-bphabs           11079  chmhs-tetradi-aco-tsdap11029  bimhs-mepipen2-meto-betadcph      11080  chhs-24thiz-mecpo-zdabs11030  bz-eta-fo-mezphe                  11081  phpip-props-mecpo-betadcph11031  thpym-mepazin-chexo-betapy        11082  me2py-pnymea-eoco-mezphe11032  thpym-edian2-mes-bnsdap           11083  dmbim-m24thizman2-peo-11033  bhs-am3diaz-oem-bnsdap                   betadcph11034  amim-mea-mes-csdap                11084  im-25oxman2-fo-betapy11035  morhs-tetradi-no2-glubzla         11085  pippy-pyma2-emo-bhsdab11036  mam2py-m25thiz-cno-psdap          11086  bimhs-ms-hso-asppha11037  gua-am3-oem-nzdab                 11087  imhs-trias-cno-glyzdap11088  dhim-am3diaz-emo-bhsdab            11139  ec-pipmea-meo-bphabs11089  2py-trias-men-betaet               11140  2py-thizn-5pho-betainyl11090  amim-pipa-5pho-bhsdab              11141  imhs-mepipe-mes-zdap11091  pippy-amn2-no2-zdab                11142  thpym-24thiman-eoco-bnsdap11092  npip-pipmea-meteto-zlys            11143  am2py-mepipe-men-aspbzla11093  dhim-pymea-mes-csdap               11144  bhs-dimephmem-men-glyzdap11094  emnim-pymea-men-thizzdap           11145  2py-mepipe-no1-psdab11095  nmhs-m25oxman2-emo-psdap           11146  dhim-pipmeo-ocho-asppha11096  thpym-diphmem-no1-bsdap            11147  bimhs-mepipe2-oem-nbetab11097  mam2py-eta-imo-asppha                     naphth11098  bim-amo2-mes-bnsdap                11148  bim-dimen-no2-bsdap11099  amim-propa2s-mes-betadcph          11149  bim-tetradi-mes-betadcph11100  mam2py-din-hso-glubzla             11150  dpam-24thizman2-ocho-bhsdab11101  2py-25oxman2-no1-zdap              11151  impy-dimephmep-chexo-aspbzla11102  bimhs-amn2-men-psdab               11152  menim-mepipen2-meo-betadcph11103  bimhs-dimen-ocho-oxal              11153  pippy-trias-oeto-zdap11104  imhs-edian2-no2-bsdap              11154  2py-eta-no1-zdabs11105  me2py-m25thizman2-no1-csdap        11155  bim-m25thizman2-pheo-zdap11106  impy-din-no1-zdabs                 11156  2py-25oxman2-no2-psdab11107  moegua-dimephmep-men-bhsdap        11157  bimhs-diphmem-no2-zorn11108  amim-mepipe2-oem-nzdab             11158  bhs-mepipen2-daco-zdabs11109  imhs-diphmem-emo-mezphe            11159  pyraz-diphmep-5amo-psdab11110  thpym-pnymea-fo-glyzdap            11160  mepip-mepipe2-oem-nbeta34-11111  thpym-din-5amo-betapy                     dimeoph11112  emnim-pymea-men-glyzdap            11161  am2py-25oxman2-mes-psdab11113  bhs-amn2-5pho-bsdap                11162  dhim-dimephmem-5pho-csdap11114  me2py-am3-sem-nzdab                11163  bhs-diphmem-men-bhsdap11115  dhim-pnymea-men-psdab              11164  bhs-dimephmep-no1-bnsdap11116  bim-m24thizman2-men-mezphe         11165  bhs-m24oxman2-ocho-zdabs11117  amim-amo2-no1-psdab                11166  prhs-dis-chexo-bnsdap11118  piraz-dimephmep-ocho-              11167  mam2py-eta-meo-aspbzla
   betainyl                           11168  am2py-amn2-men-glyzdap11119  me2py-edian2-meo-bsdap             11169  hythpym-pazin-napo-csdap11120  menim-pipmea-5pho-bsdap            11170  2py-edian2-meo-bhsdap11121  me2py-m25thiz-peo-aspibua          11171  2py-mea-napo-aspaba11122  thpym-eta-men-asppha               11172  mam2py-tetradi-imo-csdap11123  bhs-pnymea-fo-bhsdap               11173  im-pnymea-5amo-betapy11124  nmor-mepipe-no1-bnsdap             11174  emnim-diphmem-no1-betaet11125  phpip-dimen-chexo-betaet           11175  me2py-props-nmo-tsdap11126  bim-dis-chexo-dfzdap               11176  piraz-pnymea-oem-betadcph11127  2py-mepipe-eoco-betapy             11177  emnim-pnymea-mmen-betapy11128  2py-dimephmep-4amo-bhsdap          11178  mepip-amn2-oem-betainyl11129  amim-24thiz-aco-dfzdap             11179  dhim-amn3-aco-bnsdap11130  2py-amn2-eoco-zdap                 11180  hythpym-25thiman2-oem-11131  chhs-m25thiz-meo-psdapee                  aspibua11132  pyrhs-mepipen2-cno-bsdap           11181  dhim-pazin-cnmo-mezphe11133  menim-25thiman2-5amo-aspibua       11182  2py-thizs-imo-zdapee11134  2py-dimen-aco-bsdap                11183  imhs-mepipe-no1-bnsdap11135  hythpym-thizn-emo-csdap            11184  impy-tridi-mommo-oxal11136  bim-pazin-no1-bhsdap               11185  a-mim-diphmep-men-zdab11137  hythpym-pnymea-imo-bnsdap          11186  thpym-amn2-ocho-zdab11138  bim-amn2-no1-bnsdap                11187  nmor-propa2s-mes-aspibua11188  emnim-m25thiz-aco-zdapee         11238  piraz-m25thiman2-chexo-zdap11189  am2py-dimephmep-mes-betadcph     11239  ec-pymea-no1-aval11190  moegua-mepipe-daco-dfzdap        11240  dmbim-ams2-men-glupha11191  2py-edian2-nmo-zdab              11241  2py-pnymea-napo-zdap11192  thpym-butn-mommo-psdapee         11242  impy-amo2-chexo-glupha11193  thpym-eta-oem-asppha             11243  2py-thizs-no2-bphabs11194  ibhs-pymea-meo-csdap             11244  cl3pyme-24thizman2-11195  thpym-mepipe-mes-zdab                   5amo-glyzdap11196  mepip-diphmep-mes-ibsdap         11245  piraz-pazin-emo-glupha11197  dhim-m25thiz-napo-zlys           11246  bimhs-trias-eoco-bphabs11198  pippy-mepipen2-eoco-zdap         11247  2py-butn-fo-aspbzla11199  pyrhs-am2-sem-nbetabnaphth       11248  me2py-pyma2-men-betapy11200  nmor-tridi-napo-zdap             11249  bim-mepazin-5amo-zdap11201  imhs-edian2-mmen-psdapee         11250  bim-edian2-meo-zdap11202  chhs-mepipe-oem-thizzdap         11251  imhs-amo2-cno-glyzdap11203  impy-pazin-no1-betapy            11252  thpym-m24thiz-emo-betainyl11204  pippy-amn3-peo-psdab             11253  hythpym-pipa-cnmo-zdab11205  pippy-dimephmem-oem-zdap         11254  pippy-eta-imo-thizzdap11206  emnim-amn2-5amo-betapy           11255  bhs-24thiz-fo-glyzdap11207  piraz-3diaz-paco-csdap           11256  bhs-amn2-ocho-psdab11208  dmbim-amn2-mes-aspaba            11257  chmhs-mepazin-meo-aspbzla11209  bim-pnymea-fo-betainyl           11258  nmhs-thizn-chexo-glyzdap11210  c13pyme-25oxman2-eoco-           11259  imhs-amn2-meto-mezphe
   aspbzla                          11260  thpym-eta-no1-bsdap11211  moegua-tetras-ocho-mezphe        11261  2py-eta-5pho-bnsdap11212  mepip-pipmeo-4amo-bhsdap         11262  me2py-eta-oeto-mezphe11213  bim-dis-men-aspaba               11263  fthpym-dimen-no1-psdap11214  ppy-pipmea-eoco-bnsdap           11264  me-24thiman-chexo-glyzdap11215  pyraz-edian2-napo-psdab          11265  pippy-dis-ocho-asppha11216  hythpym-24thiman2-meto-zdap      11266  chhs-m24thizman2-men-aspibua11217  pippy-amn2-meo-bhsdab            11267  am-tetradi-baeo-glubzla11218  dpam-mea2s-aco-glyzdap           11268  thpym-edia2-sem-nbeta34-11219  2py-thizo-cnmo-bnsdap                   dimeoph11220  bim-tetradi-meo-asppha           11269  thpym-eta-meo-zdab11221  pippy-pazin-chexo-bhsdab         11270  nmhs-24thizman2-no1-mezphe11222  emnim-diphmep-chexo-zdabs        11271  bim-3diaz-oem-bhsdap11223  imhs-m24thiman2-meo-csdap        11272  prhs-edian2-pyo-csdap11224  bimhs-mepipen2-napo-tsdap        11273  pippy-25oxman2-no1-dfzdap11225  imhs-25thiman2-no1-bnsdap        11274  gua-dimen-meo-psdapee11226  thpym-m25thizman2-chexo-         11275  thpym-dis-mes-zdab
   bnsdap                           11276  am2py-pyma2-men-betainyl11227  ppy-ams2-oeto-csdap              11277  impy-dimephmep-cpro-bnsdap11228  dhim-tetradi-meto-glyzdap        11278  bhs-mepipe2-sem-nbeta3-11229  bimhs-mea-imo-bphabs                    4dimeoph11230  bhs-25oxman2-napo-betainyl       11279  amim-pipa-oeto-csdap11231  pyr-dimephmem-napo-psdap         11280  chhs-propn-emo-bhsdap11232  dmthpym-pentadi-5amo-mezphe      11281  me2py-pymea-chexo-psdap11233  dmam-indan2-cpro-psdab           11282  bhs-mepipe-ocho-zdabs11234  im-eta2s-eoco-bhsdab             11283  2pmhs-m25oxman2-5amo-bphabs11235  dhim-butn-mes-osdap              11284  moegua-pazin-mes-zdap11236  impy-pentas-oem-aspbzla          11285  bhs-24thiman2-no1-osdap11237  imhs-mepipe-oem-zdab             11286  me-m25thiz-5pho-psdap11287  me2py-diphmem-imo-bsdap           11339  impy-pyma2-oem-ibsdap11288  chmhs-tridi-5amo-aval             11340  am2py-mepipe-4pho-osdap11289  2py-mepipe-meo-bhsdap             11341  pippy-diphmem-men-betapy11290  impy-amo2-napo-zdabs              11342  dhim-indan2-fo-mezphe11291  pyrhs-diphmep-imo-zdap            11343  imhs-mepipe-no1-zdap11292  am-din-no1-csdap                  11344  ec-tetradi-5amo-mezphe11293  thpym-amn3-no1-csdap              11345  mam2py-m24thizman2-mes-zdap11294  2py-eta-ocho-bnsdap               11346  bzl-amn2-paco-psdab11295  thpym-pymea-ocho-asppha           11347  bhs-tetras-daco-betapy11296  chhs-propn-no2-aspbzla            11348  pyrhs-24thiman-imo-betapy11297  thpym-amnn2-oem-bsdap             11349  me-diphmem-eoco-aspaba11298  hythpym-tridi-cno-aspbzla         11350  bim-pyma2-eoco-aspbzla11299  menim-m24thiman2-emo-zdap         11351  bim-edian2-oem-zdab11300  hythpym-tridi-fo-glyzdap          11352  chhs-eta-meto-betainyl11301  2py-amn3-emo-psdab                11353  bimhs-propn-peo-csdap11302  bimhs-amo2-no2-aspbzla            11354  n2py-m24thizman2-5pho-betapy11303  me2py-amn2-men-zdap               11355  dmbim-24oxman2-men-ppsdap11304  mam2py-indan2-5amo-zorn           11356  bhs-amn2-ocho-zdap11305  piraz-tetras-no2-aspbzla          11357  bimhs-mepipe2-oem-npsdap11306  dhim-ams2-imo-aspbzla             11358  dhim-trias-meo-bnsdap11307  moegua-propn-men-dfzdap           11359  bim-amn3-oem-betapy11308  bhs-mea-no2-bphabs                11360  2py-tridi-mes-aspbzla11309  piraz-dio-emo-mezphe              11361  dhim-amn3-5pho-betadcph11310  bim-edia2-sem-npsdap              11362  dhim-pazin-chexo-ppsdap11311  thpym-edian2-napo-aspbzla         11363  prhs-tridi-mes-bphabs11312  thpym-amn3-meteto-zdabs           11364  dmam-propn-oem-thizzdap11313  bz-25oxman2-meo-tsdap             11365  bimhs-diphmem-nmo-betainyl11314  am2py-pymea-oem-csdap             11366  imhs-props-chexo-oxal11315  thpym-eta-no2-psdap               11367  imhs-thizn-napo-bsdap11316  bim-amn2-cnmo-psdab               11368  bhs-eta-meo-bsdap11317  thpym-eta-meo-zdap                11369  amim-mepipen2-emo-betapy11318  2pmhs-diphmem-emo-mezphe          11370  thpym-ms-men-bnsdap11319  imhs-25oxman2-imo-bsdap           11371  2py-pipa-imo-glyzdap11320  bimhs-propa2s-fo-csdap            11372  imhs-diphmep-5amo-betapy11321  phpip-thizn-pyo-aval              11373  dmbim-25thizman2-emo-bhsdap11322  pippy-amo2-meo-bphabs             11374  emnim-mepazin-eoco-zdabs11323  bhs-eta-no1-psdab                 11375  imhs-tetradi-meo-bphabs11324  pippy-am3-sem-nbetabnaphth        11376  2py-eta-eoco-psdab11325  mam2py-pyma2-napo-betainyl        11377  moegua-tetradi-meto-bphabs11326  pippy-dich-eoco-bhsdap            11378  z-dimephmem-5amo-betadcph11327  impy-24thizman2-cpro-psdap        11379  thpym-eta-5pho-zdap11328  bim-amo2-paco-bnsdap              11380  bim-amn2-meo-psdap11329  amim-2pazin-aco-mezphe            11381  dhim-diphmem-imo-betainyl11330  n2py-24thiz-cno-bnsdap            11382  bimhs-m25oxman2-emo-bsdap11331  thpym-ams2-imo-csdap              11383  chhs-tetradi-peo-psdap11332  bhs-amn3-imo-zdabs                11384  piraz-propa2s-fo-bnsdap11333  pippy-edian2-5pho-bphabs          11385  mepip-mepazin-fo-bhsdap11334  pippy-thizs-5amo-asppha           11386  pippy-dimen-baeo-bhsdab11335  amim-thizs-meteto-glupha          11387  amim-pipa-emo-psdap11336  2py-24thiman-no2-bsdap            11388  dpam-mepipe-men-bsdap11337  bim-mepipe-5pho-psdap             11389  bhs-butn-mmen-bhsdap11338  prhs-indan2-ocho-aspibua          11390  morhs-diphmep-cno-bnsdap11391  thpym-pazin-oem-psdap             11441  mam2py-am2-oem-nbeta34-11392  imhs-pazin-5pho-bsdap                    dimeoph11393  moegua-ams2-napo-zdabs            11442  im-pazin-fo-bhsdap11394  bhs-24thiz-fo-thizzdap            11443  am2py-amn2-meo-bhsdab11395  bhs-din-emo-mezphe                11444  mam2py-amn3-mes-betaet11396  am2py-dimen-ocho-csdap            11445  impy-n2o2n-cno-bsdap11397  nmhs-mepipe-5pho-aspbzla          11446  imhs-trias-no1-bhsdap11398  pyr-eta-paco-bnsdap               11447  mam2py-pymea-ocho-bhsdap11399  imhs-dimephmep-oem-csdap          11448  amim-24thizman2-peo-bhsdab11400  me2py-mepipen2-ocho-betadcph      11449  2py-amn2-5amo-glubzla11401  bim-amn2-no2-psdab                11450  bzl-mepazin-meo-aspbzla11402  bim-mepipe-no1-psdab              11451  amthiaz-pazin-men-betapy11403  pippy-pnymea-5amo-bhsdab          11452  dhim-amn3-5pho-betadcph11404  am2py-24thizman2-oem-bnsdap       11453  gua-dimen-napo-betapy11405  amim-pipa-4amo-aspibua            11454  pippy-amo2-meto-betadcph11406  dpam-25oxman2-men-mezphe          11455  amim-dimen-men-csdap11407  piraz-dimephmep-no1-betapy        11456  bimhs-m25thizman2-eoco-11408  impy-24thiz-chexo-glyzdap                dfzdap11409  hythpym-pnymea-paco-zorn          11457  me2py-pnymea-paco-dfzdap11410  mam2py-pipa-eoco-csdap            11458  amim-pyma2-5amo-dfzdap11411  piraz-mepipe-emo-bphabs           11459  dhim-ams2-meo-bsdap11412  deam-ams2-napo-betapy             11460  bimhs-m24thizman2-mes-oxal11413  n2py-pnymea-chexo-betainyl        11461  bim-am2-sem-nbetabnaphth11414  me2py-propn-emo-asppha            11462  bhs-pazin-eoco-bhsdap11415  am2py-m24thizman2-pheo-           11463  dmam-thizn-nmo-bhsdab
   aspbzla                           11464  impy-ams2-chexo-asppha11416  bim-dimephmep-ocho-zdapee         11465  bzl-ams3-meo-psdap11417  bzl-thizn-no1-thizzdap            11466  2py-24thizman2-mmen-csdap11418  dpam-pipmes-no1-betainyl          11467  nmor-diphmem-oem-mezphe11419  pyr-tridi-chexo-psdab             11468  ec-tetradi-eoco-betapy11420  dhim-pymea-5pho-aspibua           11469  bzl-eta2s-meo-bnsdap11421  bimhs-24thizman2-fo-aspibua       11470  pyrhs-pazi2n-no1-zdab11422  impy-eta-ocho-bhsdap              11471  me2py-pentas-mes-mezphe11423  prhs-n24thiman-aco-aspibua        11472  nim-pymea-oeto-tsdap11424  am2py-pipmea-imo-betapy           11473  imhs-mepipe-oem-zorn11425  nim-pentas-emo-psdap              11474  thpym-eta-eoco-psdap11426  amim-pipmea-emo-zdab              11475  2py-pazin-oem-zdab11427  me2py-pipa-chexo-dfzdap           11476  imhs-24thiz-meo-aspbzla11428  am4py-thizn-men-bsdap             11477  ibhs-mepipe-mes-bhsdab11429  pippy-indan2-oeto-zdabs           11478  fthpym-dimen-oem-mezphe11430  amim-amo2-baeo-bsdap              11479  dpam-ams2-meo-aspaba11431  impy-amn2-5amo-psdab              11480  phhs-edian2-eoco-psdap11432  amim-mepipen2-peo-zdap            11481  dpam-mea-mes-bsdap11433  bzl-hexas-emo-bsdap               11482  bhs-tetradi-5amo-glyzdap11434  bim-pnymea-chexo-bsdap            11483  me2py-tridi-ocho-bhsdap11435  dmam-25thiman2-meo-betapy         11484  thpym-diphmem-5pho-aspaba11436  pippy-diphmep-meo-bsdap           11485  menim-amo2-pyo-dfzdap11437  cl3pyme-diphmep-no2-zdab          11486  dhim-m25thiz-imo-psdab11438  2py-amn2-mes-bnsdap               11487  imhs-diphmem-oem-betadcph11439  dmbim-m24thiz-meo-mezphe          11488  nim-m24thizman2-eoco-aspibua11440  ppy-dimephmep-5amo-dfzdap         11489  imhs-amo2-pyo-aspbzla11490  dhim-24thiman2-chexo-psdap       11540  mam2py-24thizman2-baeo-11491  bhs-pazin-no2-psdab                     betainyl11492  bhs-edian2-5pho-bsdap            11541  thpym-mepipe-no2-betapy11493  edothpym-dio-no2-psdab           11542  impy-3diaz-eoco-zlys11494  piraz-m24thizman2-meo-zorn       11543  bim-mea2s-paco-psdab11495  dmam-am3-oem-nbetameph           11544  amim-hexas-5pho-dfzdap11496  2py-m24thizman2-peo-betadcph     11545  morhs-dimephmep-ocho-csdap11497  imhs-tetradi-napo-zdab           11546  2py-m25thiz-5pho-betapy11498  am2py-amn3-meo-glyzdap           11547  thpym-diphmep-oem-bnsdap11499  bimhs-tetradi-mes-oxal           11548  me2py-pipmeo-no2-asppha11500  me2py-indan2-chexo-zdap          11549  4pmhs-edian2-cnmo-csdap11501  impy-ams2-mommo-bphabs           11550  hythpym-24thizman2-meo-11502  thpym-25oxman2-baeo-aspibua             aspbzla11503  bimhs-trias-hso-mezphe           11551  piraz-pipa-mes-bnsdap11504  bhs-pnymea-no2-zdab              11552  piraz-pipmes-chexo-psdab11505  thpym-amn3-ocho-bhsdap           11553  bim-edian2-no1-bnsdap11506  bimhs-thizn-men-csdap            11554  bim-mepipe-5pho-bsdap11507  dmthpym-amn3-napo-bphabs         11555  am4py-pnymea-no1-dfzdap11508  pyrhs-pazi2n-baeo-dfzdap         11556  bimhs-dis-ocho-zdap11509  amthiaz-pipa-cnmo-bphabs         11557  thpym-thizn-oeto-asppha11510  imhs-amo2-pro-psdab              11558  menim-mea-emo-zdabs11511  dmbim-ams2-5amo-glupha           11559  fthpym-pnymea-peo-aspibua11512  pyrhs-24oxman2-5pho-psdab        11560  bim-tetras-eoco-bhsdap11513  bim-amo2-5amo-bhsdap             11561  ec-am2-oem-nbetameph11514  me2py-edian2-mommo-zdabs         11562  impy-trias-no1-betapy11515  2pmhs-24thiz-no1-glyzdap         11563  thpym-amn2-no2-zdap11516  me2py-eta-mes-dfzdap             11564  pippy-eta-no2-betainyl11517  moegua-eta-cnmo-aspbzla          11565  am2py-trias-no1-betadcph11518  am2py-dis-eoco-csdap             11566  2py-25oxman2-imo-betainyl11519  chhs-trias-5pho-mezphe           11567  impy-thizn-meo-betadcph11520  hythpym-m24thizman2-oem-         11568  pippy-mepipe-mecpo-psdap
   asppha                           11569  cl3pyme-25thizman2-mecpo-11521  prhs-pymea-oeto-mezphe                  bnsdap11522  chmhs-pipa-mes-psdab             11570  me2py-tridi-5pho-betadcph11523  emnim-pazin-mommo-psdap          11571  impy-25thiman2-no1-psdab11524  me2py-eta-oem-dfzdap             11572  ec-am3-oem-nbeta34dimeoph11525  pippy-pazin-no1-zdab             11573  impy-eta2s-napo-mezphe11526  impy-25oxman2-meo-asppha         11574  bhs-pazi2n-no1-bhsdap11527  hythpym-ams2-no1-asppha          11575  thpym-edian2-no1-bnsdap11528  pippy-ms-eoco-dfzdap             11576  bhs-24thizman2-chexo-zdabs11529  2py-tridi-5pho-csdap             11577  bim-amo2-aco-zdapee11530  piraz-n24thiman-meo-bphabs       11578  phhs-3pazin-mes-psdap11531  bhs-24thiz-meteto-betapy         11579  amim-diaz-emo-betadcph11532  nmhs-mepazin-mes-bphabs          11580  bz-amn2-5pho-zdabs11533  prhs-dimen-emo-betadcph          11581  dmbim-mepipe-no2-aspbzla11534  ec-dio-no1-bhsdab                11582  impy-24thiz-meto-csdap11535  chhs-ms-imo-bhsdap               11583  fthpym-24thiz-oem-csdap11536  npip-pipmea-mommo-glyzdap        11584  amim-24thiz-fo-bphabs11537  piraz-edian2-fo-ibsdap           11585  2py-mea2s-napo-betaet11538  mam2py-amn2-fo-betainyl          11586  pyrhs-pyma2-cpro-glyzdap11539  piraz-amn2-meo-psdap             11587  pyraz-am3-oem-nbetapy11588  cl3pyme-ams3-5pho-bphabs          11639  bim-trias-emo-zdap11589  bhs-trias-imo-bphabs              11640  dmthpym-24thiz-5pho-zdabs11590  bimhs-dimen-mes-zdab              11641  pyr-pazin-imo-betapy11591  hythpym-edian2-ocho-betapy        11642  impy-m25thiz-fo-bsdap11592  pippy-amn3-baeo-zlys              11643  dmbim-eta2s-chexo-bnsdap11593  hythpym-25oxman2-paco-glupha      11644  piraz-mepipe2-sem-nbeta34-11594  dhim-mepazin-men-dfzdap                  dimeoph11595  bim-trias-fo-mezphe               11645  impy-dis-5amo-zdab11596  bhs-eta-eoco-zdab                 11646  impy-dimephmep-ocho-bnsdap11597  im-dich-imo-betadcph              11647  am2py-din-ocho-psdab11598  am4py-m24thizman2-no2-dfzdap      11648  mam2py-eta2s-imo-glyzdap11599  imhs-mepipe-no2-bnsdap            11649  dpam-dimephmem-no2-betadcph11600  hythpym-ms-daco-asppha            11650  amim-pipmea-imo-thizzdap11601  nmhs-edian2-eoco-betadcph         11651  bhs-dis-no1-betadcph11602  pippy-pyma2-men-betadcph          11652  imhs-ams2-fo-ibsdap11603  2py-mepipe-meo-zdap               11653  dhim-mepipen2-no1-glupha11604  chhs-am2-oem-nbetabnaphth         11654  imhs-dimen-men-psdab11605  phhs-dimephmep-pyo-zdapee         11655  2py-ams2-cpeo-aspbzla11606  am-mepipe-pyo-betadcph            11656  thpym-edian2-eoco-zdap11607  bhs-eta-mes-zdap                  11657  thpym-ams3-emo-zdabs11608  pippy-pentadi-meto-aval           11658  me-24thiz-emo-mezphe11609  4pmhs-ams2-5amo-dfzdap            11659  2pmhs-diphmem-pyo-zdabs11610  imhs-eta-meo-psdab                11660  menim-diphmep-peo-asppha11611  nmor-24thiman-napo-betapy         11661  dhim-mepipe2-sem-nbeta34-11612  pyraz-din-5amo-mezphe                    dimeoph11613  prhs-mepipen2-mes-ibsdap          11662  imhs-mepipe-mes-psdab11614  ppy-pipmeo-men-psdap              11663  dmthpym-trias-mes-bhsdab11615  2py-mepipe-no1-zdap               11664  nmor-pipmes-men-glupha11616  am-mea-chexo-aspbzla              11665  me2py-dimephmem-fo-bhsdap11617  bim-eta-oem-betapy                11666  piraz-pnymea-napo-bphabs11618  bim-25oxman2-fo-betapy            11667  mepip-dimephmem-5pho-11619  thpym-25thiz-oem-glubzla                 betadcph11620  me2py-25thizman2-meo-aspbzla      11668  imhs-amn2-eoco-zdap11621  dhim-pymea-meo-bhsdap             11669  dhim-amnn3-ocho-dfzdap11622  moegua-mepipe2-sem-nbeta34-       11670  dpam-pymea-cno-csdap
   dimeoph                           11671  me2py-pyma2-emo-zdap11623  2py-eta-paco-zdab                 11672  bhs-pipmes-napo-aspibua11624  hythpym-diphmem-5amo-bhsdab       11673  bim-amo2-no2-aval11625  bim-mepazin-emo-csdap             11674  am4py-trias-imo-psdap11626  piraz-dimephmem-emo-psdab         11675  impy-din-nmo-bhsdab11627  bimhs-3diaz-fo-psdab              11676  bhs-hexas-meteto-zdap11628  thpym-dipch-emo-betainyl          11677  thpym-mepipe-meo-bsdap11629  am2py-indan2-5amo-psdab           11678  piraz-pipa-5pho-glubzla11630  pyrhs-pipmea-napo-psdapee         11679  piraz-tridi-no2-aspibua11631  imhs-hexadi-imo-dfzdap            11680  thpym-mea-mes-dfzdap11632  ppy-tridi-paco-psdapee            11681  bim-mepipe-ocho-psdab11633  amim-amo2-cpeo-dfzdap             11682  prhs-pyma2-fo-psdap11634  bimhs-pazin-daco-csdap            11683  imhs-ams2-eoco-mezphe11635  cl3pyme-am3diaz-eoco-zdap         11684  mam2py-dich-mommo-csdap11636  hythpym-mepipe-cpeo-psdap         11685  bim-edian2-eoco-bsdap11637  me2py-props-mes-psdap             11686  mam2py-pyma2-eoco-psdapee11638  thpym-eta2s-napo-mezphe           11687  phhs-diphmem-imo-zdap11688  mam2py-mea-cpeo-dfzdap             11740  cl3pyme-ams2-eoco-psdab11689  bim-amn2-no2-betapy                11741  pippy-propa2s-5pho-bsdap11690  bhs-edian2-meo-zdab                11742  thpym-m25thiz-5amo-ibsdap11691  im-ams2-emo-thizzdap               11743  bim-edian2-ocho-psdab11692  hythpym-24thiz-oem-osdap           11744  imhs-pazin-cnmo-bnsdap11693  n2py-din-meo-bhsdap                11745  dhim-25oxman2-chexo-dfzdap11694  imhs-dimen-emo-betadcph            11746  amim-mepipen2-5pho-betapy11695  piraz-25oxman2-men-aspbzla         11747  impy-pyma2-no1-zdab11696  pippy-thizn-mecpo-bphabs           11748  emnim-trias-napo-bsdap11697  pyrhs-pymea-imo-bnsdap             11749  me2py-amn2-meteto-aspbzla11698  pippy-edian2-chexo-asppha          11750  impy-diphmem-5pho-osdap11699  chhs-pnymea-cpeo-bhsdab            11751  thpym-mepipe-imo-zdab11700  pippy-amo2-oem-betainyl            11752  thpym-pentas-emo-betapy11701  me2py-indan2-men-mezphe            11753  amim-m25thizman2-emo-bsdap11702  bimhs-tetradi-mecpo-asppha         11754  impy-diphmep-emo-mezphe11703  imhs-eta-mes-zdab                  11755  2py-amn2-meo-bhsdap11704  dpam-m24oxman2-baeo-betapy         11756  me2py-eta-cnmo-betadcph11705  imhs-pazin-ocho-bhsdap             11757  pippy-mepipen2-cno-csdap11706  ppy-thizn-cpro-mezphe              11758  prhs-tetradi-no2-aspbzla11707  imhs-24thizman2-meo-bhsdab         11759  thpym-eta-mes-psdap11708  ibhs-mepipen2-ocho-csdap           11760  thpym-ams2-ocho-betadcph11709  mam2py-mepipe-hso-zdap             11761  imhs-mepipe-5amo-betapy11710  bhs-dio-eoco-dfzdap                11762  thpym-mepipe-mes-psdab11711  pyraz-indan2-mes-csdap             11763  bim-dio-no2-bsdap11712  bim-m25thiz-eoco-bsdap             11764  pippy-m24thizman2-fo-aval11713  thpym-tridi-no1-zdab               11765  dpam-thizn-baeo-psdapee11714  piraz-amn3-pyo-bsdap               11766  hythpym-m24thiman2-fo-zdabs11715  bim-amn2-no1-zdab                  11767  thpym-amn2-no2-bsdap11716  bhs-edian2-no1-psdab               11768  2py-pipmea-napo-betapy11717  moegua-amn2-imo-zdab               11769  2py-dis-5amo-zdab11718  dmam-edian2-meo-aspaba             11770  bim-din-imo-glyzdap11719  impy-25thiman2-nmo-psdap           11771  bim-pazin-chexo-oxal11720  bhs-mepipe-no1-psdap               11772  impy-eta-mes-bsdap11721  imhs-diphmem-imo-psdap             11773  nim-eta-imo-zdabs11722  mam2py-pnymea-chexo-glyzdap        11774  amim-pymea-imo-psdap11723  2py-m24oxman2-ocho-csdap           11775  tolhs-dimen-cpro-bnsdap11724  tolhs-eta-paco-glyzdap             11776  dpam-mepazin-men-mezphe11725  chmhs-pipmea-oeto-betadcph         11777  2py-mepipe-5pho-bsdap11726  im-diphmem-baeo-betapy             11778  dpam-pipa-no1-mezphe11727  am4py-tridi-fo-betapy              11779  bimhs-m25thizman2-5amo-psdap11728  dhim-m24thizman2-mmen-psdab        11780  im-pymea-fo-bsdap11729  hythpym-25thiman2-5pho-csdap       11781  thpym-amn2-no1-psdap11730  mam2py-amn2-napo-asppha            11782  phhs-dimephmep-no2-bsdap11731  bimhs-pazi2n-eoco-zdabs            11783  am2py-thizn-ocho-glyzdap11732  amthiaz-amn3-fo-zdabs              11784  npip-trias-hso-dfzdap11733  impy-eta2s-fo-bhsdap               11785  piraz-mepipen2-napo-bhsdab11734  bhs-25oxman2-fo-bhsdab             11786  thpym-pymea-napo-asppha11735  am-eta-paco-aspibua                11787  4pmhs-pipa-no2-betadcph11736  2py-pazin-meo-bhsdap               11788  4pmhs-mepipe2-oem-nbetameph11737  dmbim-pipmea-baeo-bnsdap           11789  tolhs-eta-men-bhsdab11738  impy-amn2-cno-aspibua              11790  bhs-amn2-no2-bhsdap11739  2py-pymea-no1-bsdap                11791  impy-ams2-nmo-betadcph11792  bimhs-hexas-chexo-aval           11844  dmthpym-am2-oem-nbetameph11793  pyrhs-dis-no2-bhsdap             11845  amthiaz-m24thizman2-11794  me2py-3pazin-imo-bsdap                  emo-bhsdap11795  npip-edian2-5amo-aspibua         11846  bz-ams2-5pho-psdab11796  imhs-propn-5amo-bphabs           11847  tolhs-edian2-no1-bhsdab11797  im-24thiz-mes-betainyl           11848  am4py-hexas-imo-bphabs11798  cl3pyme-pentadi-eoco-mezphe      11849  mam2py-eta2s-emo-zdap11799  me2py-amn2-fo-zdab               11850  bhs-eta-oem-bsdap11800  bhs-n2nme2n-5amo-psdab           11851  am-amn3-chexo-betadcph11801  cl3pyme-m24thiman2-ocho-oxal     11852  bhs-eta2s-5pho-bphabs11802  amim-pipmes-meo-psdab            11853  bz-m24thizman2-no1-asppha11803  dmthpym-dimen-mes-aspibua        11854  bhs-24thizman2-men-glyzdap11804  amim-amn2-5pho-bhsdab            11855  impy-dimephmep-cpeo-osdap11805  bimhs-mepipe-eoco-asppha         11856  4pmhs-dimen-imo-bhsdab11806  bhs-pipmes-no1-bsdap             11857  imhs-am3-oem-nbetameph11807  2py-dimephmep-mes-zdap           11858  bimhs-m24oxman2-5pho-bhsdap11808  chmhs-dimephmem-meo-bsdap        11859  thpym-amn2-no2-asppha11809  imhs-edian2-no2-bhsdap           11860  amim-butn-eoco-osdap11810  amim-24thizman2-4pho-asppha      11861  2py-dipch-napo-csdap11811  piraz-dimephmem-emo-oxal         11862  mepip-mea2s-5pho-bhsdap11812  bimhs-diaz-oem-psdab             11863  mam2py-dipch-imo-bphabs11813  hythpym-pazin-mommo-bnsdap       11864  2py-pymea-no2-zdapee11814  pippy-tetradi-meteto-asppha      11865  me-edian2-emo-csdap11815  pippy-eta2s-mecpo-mezphe         11866  impy-dimephmep-fo-betadcph11816  bhs-pnymea-5pho-zdabs            11867  ibhs-tetradi-no1-psdap11817  z-dimephmep-ocho-psdap           11868  pyrhs-diaz-paco-dfzdap11818  fthpym-mea-chexo-psdab           11869  bhs-amn2-oem-bnsdap11819  bim-amo2-mes-psdab               11870  pyrhs-24thiz-mes-bphabs11820  bim-amn2-no2-zdab                11871  thpym-thizs-fo-psdab11821  dmthpym-pipmea-5pho-betainyl     11872  me2py-din-napo-psdab11822  gua-edia2-oem-nbeta34dimeoph     11873  hythpym-diphmem-4amo-11823  mam2py-amo3-mes-zdapee                  betainyl11824  2py-edian2-meo-bphabs            11874  amim-edian2-paco-bhsdab11825  hythpym-tridi-ocho-glyzdap       11875  2pmhs-amo3-meto-bhsdab11826  imhs-pazin-5pho-zdap             11876  mepip-edia2-oem-npsdap11827  bhs-diphmem-oem-bnsdap           11877  2py-amn2-meo-betapy11828  bhs-propa2s-5amo-bhsdap          11878  impy-m24thizman2-paco-asppha11829  2py-mepipe-mes-psdab             11879  bhs-eta-ocho-bhsdap11830  imhs-mepazin-4amo-glyzdap        11880  npip-eta2s-pro-betainyl11831  pippy-dimephmep-cpro-csdap       11881  mam2py-tetradi-ocho-asppha11832  2py-24thizman2-4amo-psdab        11882  am4py-24oxman2-napo-betapy11833  pippy-m25oxman2-pheo-zdabs       11883  cl3pyme-pyma2-4amo-bsdap11834  piraz-mepipen2-meo-zdap          11884  bhs-eta-5amo-betapy11835  piraz-pipa-eoco-bphabs           11885  bhs-edian2-eoco-bsdap11836  imhs-mepipe-no1-psdab            11886  2py-pazin-no2-betapy11837  phhs-diphmem-men-zlys            11887  thpym-pymea-oem-bhsdap11838  thpym-pazin-no1-psdap            11888  bz-mepazin-no1-bhsdab11839  bzl-amn2-ocho-bphabs             11889  thpym-2pazin-mes-bhsdab11840  dhim-am3-sem-nzdab               11890  bim-props-peo-zdap11841  im-m25thiz-5amo-psdapee          11891  thpym-eta-no1-bhsdap11842  hythpym-amn2-mommo-betainyl      11892  am2py-m24thizman2-oeto-zdabs11843  2py-edian2-meo-bsdap             11893  nmhs-mepipen2-5amo-zdabs11894  nmhs-dimen-no1-aspaba             11946  chmhs-25oxman2-meo-psdab11895  impy-eta-napo-bsdap               11947  bim-diphmem-fo-aval11896  2py-25thizman2-eoco-asppha        11948  mam2py-mepazin-ocho-asppha11897  impy-25oxman2-meo-psdap           11949  emnim-pyma2-mecpo-zdabs11898  imhs-thizn-ocho-betadcph          11950  am2py-trias-no1-dfzdap11899  impy-edian2-mommo-bnsdap          11951  bim-pazin-5pho-zdab11900  phpip-eta-napo-glupha             11952  ec-dimen-emo-zdab11901  imhs-pipmes-oeto-bhsdab           11953  hythpym-din-men-bsdap11902  thpym-m24thizman2-meo-asppha      11954  amthiaz-amn2-5pho-aspaba11903  pyraz-amn2-fo-aspibua             11955  morhs-tridi-eoco-asppha11904  pippy-mepazin-mmen-asppha         11956  hythpym-25oxman2-emo-osdap11905  deam-dis-oem-betainyl             11957  me2py-edia2-sem-nbetameph11906  imhs-25oxmnan2-oem-betapy         11958  2pmhs-pipa-pheo-betapy11907  bim-pazin-5pho-zdap               11959  imhs-mepipe-eoco-psdap11908  amim-mepazin-ocho-asppha          11960  amim-dis-cpeo-betaet11909  dhim-25oxman2-cpro-glyzdap        11961  bimhs-mepazin-mecpo-mezphe11910  thpym-amn3-meo-betapy             11962  npip-dimephmep-pro-bsdap11911  2py-24thizman2-fo-zdab            11963  dhim-tetras-meteto-aspibua11912  bim-tetradi-ocho-tsdap            11964  bimhs-m24thiz-men-aspibua11913  imhs-amn3-no1-bhsdap              11965  imhs-pazin-no1-psdab11914  chmhs-dimephmem-imo-aspaba        11966  imhs-eta-no2-psdab11915  amthiaz-24thizman2-no2-bsdap      11967  bhs-trias-cpeo-bnsdap11916  bimhs-trias-no1-aval              11968  hythpym-24thizman2-meo-11917  me2py-dio-imo-bsdap                      asppha11918  pyrhs-pazin-meteto-dfzdap         11969  mam2py-tridi-meo-bphabs11919  thpym-pipmea-eoco-bnsdap          11970  2py-pipmea-cno-zdap11920  hythpym-amo2-4amo-psdap           11971  am-m25thiz-mes-betapy11921  dmam-thizn-5amo-glyzdap           11972  bimhs-3diaz-chexo-betapy11922  bhs-eta-mes-betapy                11973  2pmhs-diaz-eoco-psdapee11923  impy-pipa-imo-psdab               11974  pyrhs-pymea-emo-dfzdap11924  pyrhs-amn2-no1-bnsdap             11975  2py-dimen-hso-bhsdab11925  bim-mea2s-fo-mezphe               11976  bim-edian2-no1-betapy11926  me2py-pazin-hso-glyzdap           11977  bimhs-din-no2-tsdap11927  tolhs-pipmea-cpro-bphabs          11978  bzl-pipmeo-imo-bsdap11928  hythpym-diphmep-meto-dfzdap       11979  ppy-dich-ocho-betadcph11929  hythpym-2pazin-daco-aspibua       11980  mam2py-pymea-mes-zorn11930  amthiaz-trias-napo-psdapee        11981  thpym-eta-no1-bphabs11931  pyrhs-tridi-5pho-bhsdab           11982  me2py-pyma2-no2-betapy11932  pippy-amo2-chexo-csdap            11983  am2py-mepipe2-oem-npsdap11933  pyrhs-dimephmem-ocho-psdap        11984  thpym-m25thiz-mes-zdabs11934  chhs-dimephmem-meo-zdabs          11985  pyraz-dimephmep-no1-psdab11935  thpym-pazin-eoco-bhsdap           11986  chhs-pazi2n-emo-betadcph11936  am-thizn-fo-dfzdap                11987  me2py-3pazin-eoco-dfzdap11937  dpam-thizn-5pho-psdap             11988  imhs-eta-5pho-bhsdap11938  bhs-ms-mommo-zdap                 11989  2py-mepipe-mes-psdap11939  bhs-eta-5pho-betapy               11990  pyraz-thizn-eoco-asppha11940  pippy-24thizman2-5pho-psdap       11991  amim-m24thizman2-mes-bnsdap11941  ppy-diphmem-emo-betainyl          11992  bhs-tetradi-meo-dfzdap11942  thpym-mepipen2-emo-bsdap          11993  nim-am2-oem-nzdab11943  bim-m24thiman2-ocho-glupha        11994  nmhs-25oxman2-5pho-psdap11944  ibhs-diphmem-mes-zdap             11995  mam2py-pentadi-eoco-aspbzla11945  2py-24thiman2-5amo-psdap          11996  mam2py-ams2-chexo-csdap11997  bimhs-mepazin-chexo-oxal         12047  amim-mepipe-napo-zdabs11998  hythpym-mepazin-pro-betapy       12048  bim-edian2-5pho-zdap11999  pippy-pipmea-meo-bsdap           12049  ec-3pazin-mes-betapy12000  bhs-pazin-no1-psdab              12050  pippy-eta-fo-aspibua12001  hythpym-mea-meo-thizzdap         12051  piraz-eta-4amo-bphabs12002  bzl-edia2-sem-nbeta34dimeoph     12052  pippy-pipa-no2-bsdap12003  bimhs-dis-chexo-csdap            12053  am2py-dimen-chexo-glubzla12004  nmhs-25thiman2-5pho-bphabs       12054  am2py-pipmea-pyo-betadcph12005  2py-dipch-fo-bsdap               12055  piraz-dipch-napo-aspibua12006  prhs-mepipen2-eoco-zdab          12056  gua-pipa-men-psdab12007  imhs-mepipen2-napo-aspbzla       12057  chmhs-dis-oem-osdap12008  bim-tridi-ocho-asppha            12058  fthpym-pymea-5pho-zlys12009  phhs-m25thiz-oeto-aspbzla        12059  piraz-m25oxman2-fo-zdabs12010  mam2py-25oxman2-emo-betapy       12060  imhs-mepipe-ocho-zdap12011  thpym-eta2s-meo-csdap            12061  thpym-eta-imo-aspbzla12012  thpym-mepipe2-sem-npsdap         12062  bhs-amo3-eoco-dfzdap12013  amim-mepazin-pheo-zdabs          12063  npip-din-cpeo-betainyl12014  impy-amo2-no2-zdab               12064  me2py-edian2-men-bnsdap12015  pippy-3diaz-mes-betadcph         12065  bimhs-m24thizman2-mecpo-12016  hythpym-mepipe2-sem-                    betadcph
   nbeta34dimeoph                   12066  piraz-mepipen2-meo-zlys12017  bim-mepipe-emo-psdapee           12067  edothpym-amn3-daco-zdap12018  imhs-m24thizman2-4amo-           12068  gua-hexas-mes-csdap
   thizzdap                         12069  piraz-dimephmem-mmen-csdap12019  mam2py-24thiz-4pho-betadcph      12070  am2py-am3-sem-nzdab12020  me-pnymea-mecpo-zdap             12071  mam2py-pymea-no1-aval12021  ibhs-pnymea-mecpo-psdap          12072  z-pnymea-5amo-psdap12022  dhim-dis-eoco-zlys               12073  piraz-amo2-oem-betainyl12023  am2py-pipa-no2-betapy            12074  am2py-tetras-men-bnsdap12024  tolhs-thizn-mes-aspbzla          12075  fthpym-3pazin-chexo-bhsdab12025  bhs-m25thiz-pro-zdabs            12076  piraz-tetradi-men-aspbzla12026  am2py-am2-oem-npsdap             12077  dhim-pnymea-oem-bhsdab12027  pippy-dimen-pro-glyzdap          12078  moegua-din-oem-bhsdab12028  bim-edian2-oem-bnsdap            12079  morhs-mepipe2-oem-npsdap12029  dmthpym-m25thiz-chexo-asppha     12080  bz-diaz-oem-bnsdap12030  am2py-mepazin-no2-bnsdap         12081  pyraz-mepipe-men-bphabs12031  bhs-amn2-ocho-bnsdap             12082  imhs-mepipe-meo-bhsdap12032  amim-24thiman-aco-zdab           12083  impy-25oxman2-oem-aspbzla12033  thpym-m24thizman2-cno-dfzdap     12084  amim-diphmem-fo-betapy12034  pippy-24thizman2-mes-psdab       12085  dmthpym-thizn-4pho-oxal12035  hythpym-edian2-fo-thizzdap       12086  thpym-n2o2n-no1-zdab12036  2py-pnymea-napo-bsdap            12087  bhs-edian2-meo-bnsdap12037  amim-25oxman2-emo-zdapee         12088  hythpym-pipa-4pho-psdap12038  2py-m25thiz-men-psdapee          12089  pippy-diaz-fo-tsdap12039  bim-pazin-peo-aspibua            12090  dhim-dimephmem-paco-zdab12040  me2py-mepipe-ocho-ibsdap         12091  bhs-pazin-meo-psdab12041  2py-eta-men-betainyl             12092  phhs-24thizman2-imo-bhsdap12042  piraz-dimephmem-chexo-dfzdap     12093  thpym-dimephmep-men-glyzdap12043  amim-diphmep-5pho-glyzdap        12094  pippy-edia2-sem-nbeta34-12044  bhs-edian2-5pho-psdab                   dimeoph12045  amim-dimephmep-paco-betapy       11095  menim-pazi2n-chexo-mezphe12046  am2py-pipmea-mes-bsdap           12096  imhs-mepipe-meo-bnsdap12097  nmhs-amo2-imo-thizzdap            12146  pippy-mepipe-5amo-mezphe12098  phpip-edia2-sem-nbetameph         12147  piraz-3diaz-cnmo-zdap12099  npip-eta2s-ocho-csdap             12148  dpam-dimephmem-napo-zdap12100  fthpym-edian2-4amo-aval           12149  pippy-pazin-men-bphabs12101  am2py-ms-pheo-asppha              12150  thpym-tridi-men-betadcph12102  2py-trias-5pho-aspbzla            12151  imhs-mepipen2-5pho-aspibua12103  bhs-pazin-eoco-zdab               12152  am2py-am3-oem-nbetapy12104  impy-mepipe2-sem-nzdap            12153  dhim-din-mes-psdab12105  2py-edian2-no2-bnsdap             12154  thpym-dis-chexo-psdab12106  bim-eta-oem-zdap                  12155  piraz-dimephmep-mes-dfzdap12107  am2py-m24thizman2-meo-            12156  piraz-ams2-imo-betapy
   betainyl                          12157  2py-edian2-ocho-psdab12108  dhim-trias-5pho-betainyl          12158  piraz-diaz-cpro-asppha12109  bim-amn2-oem-bnsdap               12159  mam2py-dis-fo-bsdap12110  pippy-pipa-imo-dfzdap             12160  4pmhs-m24thizman2-aco-psdab12111  chhs-dimen-fo-betapy              12161  hythpym-ams3-emo-bsdap12112  2py-mepipe-no2-bhsdap             12162  morhs-24thizman2-emo-bsdap12113  ppy-m24thizman2-chexo-            12163  im-pyma2-ocho-bnsdap
   glyzdap                           12164  mepip-tetradi-emo-dfzdap12114  piraz-n24thiman-5amo-dfzdap       12165  piraz-tetradi-napo-aspibua12115  morhs-din-men-zdap                12166  dmthpym-mepipen2-meo-glyzdap12116  mam2py-amn3-peo-psdab             12167  am2py-dimephmep-cnmo-zdap12117  bim-tetradi-5amo-bhsdap           12168  bim-dimephmep-eoco-mezphe12118  mam2py-pymea-fo-zorn              12169  prhs-din-mmen-psdab12119  2py-pyma2-eoco-betapy             12170  thpym-dimephmep-5amo-bhsdab12120  amim-ams2-chexo-psdab             12171  dhim-dis-no1-bphabs12121  4pmhs-amn2-no1-betainyl           12172  pyr-24thiz-oem-bphabs12122  amthiaz-diphmep-mommo-psdap       12173  bim-din-pro-bphabs12123  bim-eta-mes-zdap                  12174  imhs-hexadi-meteto-asppha12124  deam-m25thiz-fo-betainyl          12175  deam-amn3-eoco-aspibua12125  bhs-din-eoco-bphabs               12176  mam2py-tetradi-napo-bhsdap12126  4pmhs-amn3-ocho-bphabs            12177  hythpym-ams2-meo-tsdap12127  dhim-pipa-napo-zdab               12178  2py-pazin-hso-betainyl12128  dhim-dimephmep-chexo-             12179  amim-25oxman2-meto-bphabs
   betainyl                          12180  phhs-am2-sem-nzdap12129  pyraz-mepipe-mmen-betapy          12181  piraz-dimephmep-4pho-oxal12130  me-edian2-oem-aspibua             12182  bim-eta-meo-psdab12131  am2py-m25thiz-cpro-ppsdap         12183  bhs-24thizman2-napo-bphabs12132  bz-pentadi-oem-glyzdap            12184  thpym-pazin-no1-bnsdap12133  bim-mepipen2-paco-ibsdap          12185  nim-pipa-cpro-aspibua12134  imhs-tridi-mmen-betainyl          12186  amim-dimen-eoco-betainyl12135  prhs-25oxman2-imo-bhsdab          12187  2py-amn3-meo-zdap12136  pippy-mepazin-oem-oxal            12188  me-trias-meo-zdab12137  thpym-m25thizman2-aco-zdabs       12189  am2py-dimen-no2-dfzdap12138  pippy-mepazin-cnmo-asppha         12190  piraz-dimephmem-ocho-tsdap12139  mam2py-ams3-ocho-dfzdap           12191  thpym-mepipe-no2-psdap12140  imhs-amo2-oem-bphabs              12192  me2py-pipa-no1-bsdap12141  piraz-eta2s-oeto-betapy           12193  thpym-ams3-baeo-psdap12142  piraz-dimen-imo-bsdap             12194  emnim-edia2-oem-nzdab12143  bimhs-amo2-pyo-zdabs              12195  bimhs-trias-meo-zdabs12144  deam-dimen-no1-thizzdap           12196  piraz-din-chexo-betainyl12145  am-m24thizman2-imo-aspbzla        12197  bimhs-thizn-no2-ppsdap12198  menim-pnymea-mes-zdabs             12248  bimhs-diphmem-men-bhsdap12199  imhs-pipmea-meo-asppha             12249  ec-mea2s-5pho-bhsdap12200  bhs-eta-oem-zdab                   12250  bim-24thizman2-5pho-psdap12201  fthpym-mepipe-5pho-zdab            12251  2py-mepipe-oem-bnsdap12202  bimhs-24thiman2-fo-aspibua         12252  morhs-diphmem-napo-bhsdap12203  bim-amn3-5amo-glyzdap              12253  pippy-diaz-cnmo-bsdap12204  chhs-pipa-meo-psdap                12254  dpam-amo2-napo-betadcph12205  impy-24thizman2-men-psdap          12255  thpym-dipch-eoco-dfzdap12206  npip-trias-mes-zdab                12256  impy-amn2-ocho-bsdap12207  edothpym-m24thizman2-chexo-        12257  bim-pnymea-5pho-ppsdap
   betadcph                           12258  hythpym-amo2-5amo-aval12208  me2py-dimephmep-meo-zorn           12259  z-pymea-5pho-asppha12209  im-mepipe2-oem-npsdap              12260  imhs-mepipen2-5amo-bphabs12210  dhim-am2-oem-nzdab                 12261  hythpym-mepipe-meteto-tsdap12211  fthpym-pipmes-no1-betadcph         12262  z-m24thizman2-no2-aspbzla12212  bimhs-24thiz-peo-mezphe            12263  am2py-dimephmep-imo-zdab12213  pippy-hexadi-mes-betainyl          12264  imhs-am3-sem-nbetameph12214  thpym-m24thizman2-pyo-asppha       12265  am2py-mepazin-meo-aspbzla12215  2py-amn2-5pho-bnsdap               12266  2py-amn2-oem-betapy12216  thpym-pnymea-meo-glyzdap           12267  thpym-mepipe-eoco-betapy12217  n2py-24thizman2-5amo-ppsdap        12268  bim-trias-no1-zdabs12218  piraz-diphmep-mes-psdap            12269  impy-mepipe-fo-betadcph12219  dpam-pazin-5amo-bhsdab             12270  bhs-pazin-no1-zdap12220  piraz-diphmep-meo-zdap             12271  impy-25oxman2-napo-bhsdab12221  pippy-25thiz-oem-tsdap             12272  bim-din-hso-psdab12222  amim-mepipe-oem-csdap              12273  mam2py-mepipe2-oem-nbeta34-12223  nmhs-pipa-no1-bhsdap                      dimeoph12224  pippy-m25thiz-daco-zdabs           12274  imhs-mepipe-no1-psdap12225  am2py-ams3-cpeo-glubzla            12275  me2py-amn3-mes-zdapee12226  hythpym-dis-chexo-zdap             12276  bim-pazin-eoco-bsdap12227  bhs-edian2-no1-bsdap               12277  bimhs-thizn-men-aspibua12228  ec-mepazin-fo-bhsdab               12278  bhs-diphmem-eoco-betainyl12229  amim-dimephmep-fo-psdap            12279  pyr-pipmes-fo-aspibua12230  dpam-amo2-meo-zdab                 12280  nmor-thizn-emo-zdap12231  am2py-pnymea-napo-glyzdap          12281  me-diphmep-eoco-zdab12232  mam2py-din-5amo-bphabs             12282  bz-trias-napo-aspibua12233  z-tridi-mommo-dfzdap               12283  npip-thizn-meteto-asppha12234  imhs-m24oxman2-cpro-ppsdap         12284  bhs-thizn-fo-glyzdap12235  hythpym-24thizman2-4pho-           12285  pyraz-pymea-oem-betapy
   asppha                             12286  dhim-dis-napo-dfzdap12236  2py-trias-daco-aspbzla             12287  impy-pipa-chexo-psdap12237  im-24thiman-emo-zdabs              12288  imhs-mepipe-oem-bsdap12238  imhs-dimephmep-eoco-aval           12289  n2py-ams2-meteto-thizzdap12239  2py-props-emo-dfzdap               12290  me2py-mepipen2-peo-betadcph12240  bhs-pentas-fo-psdap                12291  thpym-mepipe-5pho-zdab12241  bim-diphmep-cpeo-dfzdap            12292  amim-m25thiz-emo-betainyl12242  thpym-pyma2-imo-glyzdap            12293  am2py-diphmep-chexo-zdabs12243  me2py-pnymea-fo-zdab               12294  am-mea-mes-betadcph12244  piraz-din-no2-bnsdap               12295  2py-mepipe-no2-bsdap12245  bimhs-diaz-oem-zdab                12296  amim-pazin-chexo-zdabs12246  am2py-diphmem-aco-dfzdap           12297  cl3pyme-diphmep-eoco-zdab12247  dhim-dis-mes-betainyl              12298  dmam-dimen-men-bphabs12299  dhim-dimen-4amo-bhsdab           12350  z-tetradi-cpeo-bhsdab12300  dmthpym-mepipen2-men-bsdap       12351  bhs-eta-mes-zdab12301  am2py-mepipen2-napo-aspibua      12352  imhs-mepipe2-oem-nzdab12302  gua-propa2s-cnmo-zdapee          12353  nmhs-diphmep-men-bhsdab12303  pippy-edia2-sem-nbetameph        12354  mam2py-pazin-pyo-bphabs12304  nim-amo2-oem-zdabs               12355  pippy-pentas-emo-dfzdap12305  hythpym-24thiman-oem-mezphe      12356  hythpym-dimen-hso-zdab12306  impy-ams2-aco-mezphe             12357  imhs-eta-5pho-betapy12307  2py-dimen-napo-bsdap             12358  ibhs-thizn-no1-mezphe12308  amim-pymea-5pho-dfzdap           12359  pippy-25thiz-5pho-psdap12309  hythpym-edia2-sem-npsdap         12360  piraz-thizs-hso-psdapee12310  2py-edia2-sem-nbetabnaphth       12361  2py-pazin-oem-psdap12311  bim-edian2-mes-zdap              12362  impy-trias-oem-bphabs12312  am2py-amn3-napo-aval             12363  pippy-dis-5amo-bphabs12313  amim-hexas-oem-bsdap             12364  pyraz-am3-oem-npsdap12314  me2py-pazin-eoco-psdab           12365  ppy-diphmem-5pho-psdap12315  am2py-diphmep-no2-mezphe         12366  am2py-24thiz-pyo-zorn12316  cl3pyme-pnymea-imo-zdab          12367  am2py-pymea-napo-betaet12317  2py-amn2-eoco-bnsdap             12368  imhs-eta-no2-bnsdap12318  am2py-m24thizman2-mes-csdap      12369  hythpym-amn2-baeo-betadcph12319  pippy-dimephmem-ocho-zdab        12370  dmthpym-mepipen2-eoco-bsdap12320  2py-eta-no1-betapy               12371  phhs-m24thizman2-pheo-zdap12321  pippy-trias-pheo-dfzdap          12372  edothpym-trias-napo-zdabs12322  mam2py-diphmep-mmen-bphabs       12373  moegua-n2o2n-oem-psdap12323  amthiaz-m25thiz-men-betapy       12374  imhs-dis-pheo-psdab12324  amim-amn3-oem-bhsdap             12375  ibhs-thizn-fo-mezphe12325  amthiaz-mepipe-fo-bnsdap         12376  me2py-trias-no1-csdap12326  imhs-edian2-oem-bsdap            12377  bim-mepipe-mes-asppha12327  bim-pipmeo-napo-bnsdap           12378  am-mepipe-ocho-thizzdap12328  chmhs-ms-aco-mezphe              12379  nmhs-dimephmem-pyo-csdap12329  thpym-mepipe-fo-zdap             12380  dmbim-amn3-cnmo-betainyl12330  bim-25oxman2-cnmo-aspbzla        12381  bim-m25thiz-5pho-osdap12331  impy-diphmem-no2-asppha          12382  gua-thizn-meteto-bhsdap12332  dhim-edian2-men-csdap            12383  impy-n2o2n-napo-bhsdab12333  impy-eta-fo-aspibua              12384  fthpym-24thizman2-mommo-12334  am-dimen-cpeo-dfzdap                    dfzdap12335  prhs-pnymea-men-bhsdap           12385  2py-thizn-baeo-betadcph12336  bim-mepipe-oem-psdap             12386  imhs-pazin-no2-psdab12337  dmam-m25thiz-imo-csdap           12387  bim-mepipe-no2-bnsdap12338  pyrhs-mea-peo-mezphe             12388  dmam-din-napo-zdap12339  hythpym-amo2-napo-zdabs          12389  2py-mepazin-meo-csdap12340  imhs-amn2-mes-bnsdap             12390  am2py-edian2-emo-asppha12341  bhs-thizn-chexo-betainyl         12391  impy-trias-fo-ppsdap12342  imhs-pipmea-5amo-bnsdap          12392  ec-mepazin-meo-aval12343  mam2py-trias-aco-bsdap           12393  bhs-pipa-no1-zorn12344  hythpym-dimen-chexo-betainyl     12394  dhim-diphmep-4pho-aspbzla12345  dhim-edia2-oem-nbeta34-          12395  amthiaz-dimephmep-meteto-
   dimeoph                                 psdap12346  am2py-pipmea-hso-aspbzla         12396  mam2py-pipmea-fo-zdap12347  dhim-24thiman2-peo-psdapee       12397  morhs-m25thiz-chexo-aspbzla12348  hythpym-eta-chexo-betadcph       12398  dhim-diphmem-ocho-csdap12349  imhs-dimen-fo-bsdap              12399  amim-pyma2-no1-mezphe12400  2py-pazin-ocho-bnsdap               12452  mepip-dimephmep-4pho-glyzdap12401  am-hexadi-cpro-bhsdap               12453  bhs-thizs-no1-mezphe12402  bhs-amn2-meo-bnsdap                 12454  ec-trias-5amo-psdab12403  thpym-amo2-fo-csdap                 12455  2py-dis-pheo-csdap12404  imhs-pipmeo-meo-betainyl            12456  amim-amo2-fo-bhsdab12405  am2py-eta-5pho-zdap                 12457  bimhs-hexas-emo-betainyl12406  impy-amn2-5pho-psdap                12458  imhs-dimephmep-fo-bsdap12407  dmbim-m25thiz-oem-bhsdab            12459  bzl-edian2-ocho-zlys12408  npip-tridi-ocho-psdap               12460  mam2py-n24thiman-fo-betapy12409  dhim-dimephmem-napo-aspibua         12461  dmam-amn2-baeo-bhsdab12410  piraz-m25thiz-mommo-zdap            12462  ibhs-mepipe-no1-bnsdap12411  me2py-pymea-no1-bphabs              12463  ec-ams2-meteto-zdapee12412  pippy-dimen-napo-glupha             12464  amim-mepazin-ocho-ppsdap12413  bim-m25thiz-baeo-betainyl           12465  im-3pazin-no1-betainyl12414  emnim-mepipe2-oem-nzdap             12466  imhs-m24thizman2-oem-12415  gua-dimephmep-paco-osdap                   thizzdap12416  dhim-am2-sem-nbetabnaphth           12467  thpym-tetradi-oem-bhsdab12417  me2py-am2-oem-nbetameph             12468  mam2py-pymea-no2-ibsdap12418  me2py-24thiz-men-glyzdap            12469  mepip-ams2-ocho-glupha12419  prhs-din-ocho-aspibua               12470  dhim-24thiz-no1-zdap12420  impy-am3diaz-pheo-bphabs            12471  pippy-amn3-emo-betapy12421  pippy-mea2s-no2-bsdap               12472  2py-amn3-cno-aspibua12422  imhs-trias-oem-betapy               12473  chhs-25oxman2-napo-zdab12423  dhim-din-oem-asppha                 12474  hythpym-pnymea-ocho-zdab12424  bimhs-thizn-eoco-betadcph           12475  me2py-25thiz-fo-betapy12425  dmbim-amn3-pro-psdap                12476  impy-amn2-men-zdab12426  nim-mepipe2-sem-nbetameph           12477  pippy-m24oxman2-no1-csdap12427  amim-dich-cno-betadcph              12478  2py-props-ocho-bhsdap12428  ibhs-dio-eoco-bhsdap                12479  me2py-thizn-chexo-osdap12429  impy-dimephmep-oem-aspaba           12480  4pmhs-dimephmem-men-psdapee12430  bim-edian2-mes-bhsdap               12481  bhs-amn2-mes-zdab12431  bhs-amn2-no2-psdab                  12482  imhs-pazin-no1-bnsdap12432  thpym-24thiz-chexo-mezphe           12483  pippy-mepipe-5amo-aspbzla12433  mam2py-25thizman2-napo-zdabs        12484  imhs-pazin-eoco-bhsdap12434  thpym-amn2-5pho-zdap                12485  mam2py-m25thiz-5amo-zdab12435  thpym-pazin-fo-dfzdap               12486  bhs-thizs-no1-bhsdap12436  piraz-pymea-pheo-betaet             12487  im-props-fo-psdap12437  imhs-diaz-imo-csdap                 12488  pyr-dis-imo-bhsdab12438  chmhs-24thiz-emo-asppha             12489  me2py-pyma2-no1-aspbzla12439  thpym-ms-oem-dfzdap                 12490  pippy-propn-oem-betapy12440  bzl-am2-oem-nbetabnaphth            12491  2py-edian2-ocho-psdap12441  prhs-tetradi-paco-dfzdap            12492  2py-pazin-ocho-betapy12442  ppy-dimen-chexo-zdabs               12493  mepip-pyma2-no1-mezphe12443  im-amn3-chexo-bhsdap                12494  piraz-dimephmep-imo-csdap12444  dmam-pazin-ocho-mezphe              12495  amim-pazin-no1-asppha12445  z-trias-men-psdap                   12496  morhs-25thizman2-men-zdab12446  dhim-dimephmep-cnmo-bhsdap          12497  tolhs-tetradi-napo-zdabs12447  bimhs-25oxman2-5amo-betapy          12498  thpym-pymea-aco-bsdap12448  thpym-tridi-meo-psdap               12499  imhs-m25thiz-no1-bsdap12449  piraz-thizn-no1-betapy              12500  chmhs-amo2-meo-bsdap12450  bhs-amn3-napo-zdabs                 12501  nmor-pymea-mes-betapy12451  me2py-m25thiz-no1-glyzdap           12502  dmbim-m25thiz-ocho-aspbzla12503  imhs-mea-mes-zdabs                 12553  z-hexas-5amo-zdabs12504  am2py-mepipe-mommo-aspibua         12554  ibhs-din-mes-aspbzla12505  bim-mea-no2-asppha                 12555  amim-tetradi-fo-zdap12506  thpym-diphmep-mecpo-betapy         12556  2py-edian2-5pho-betapy12507  bhs-eta-ocho-betapy                12557  ppy-ams2-oeto-glyzdap12508  bim-mepipe-eoco-zdap               12558  hythpym-24thiz-pro-bhsdab12509  bimhs-pazin-daco-mezphe            12559  impy-edian2-5amo-csdap12510  thpym-pazin-chexo-betapy           12560  imhs-pazin-mes-psdap12511  nim-ams2-imo-betainyl              12561  edothpym-m24thizman2-ocho-12512  prhs-25oxman2-no2-betainyl                 glupha12513  hythpym-n24thiman-emo-psdab        12562  phpip-pipmea-5pho-betadcph12514  2py-diphmep-emo-bsdap              12563  amim-ams2-cpro-zdap12515  morhs-amn2-emo-zdabs               12564  imhs-hexadi-oem-asppha12516  bim-diphmep-mecpo-betapy           12565  am4py-trias-paco-betainyl12517  bim-eta-ocho-zdap                  12566  amim-dimephmem-oem-zdap12518  piraz-mepazin-eoco-betainyl        12567  impy-thizn-meo-bsdap12519  pyraz-eta-eoco-dfzdap              12568  npip-m25thiz-emo-betadcph12520  dhim-pymea-oem-dfzdap              12569  hythpym-tridi-cpro-csdap12521  pippy-m24thizman2-mommo-           12570  fthpym-mepazin-mes-glyzdap
   asppha                             12571  prhs-25oxman2-mes-bhsdap12522  bhs-mepipe-ocho-bnsdap             12572  me2py-pymea-5amo-betadcph12523  bhs-eta-no1-zdabs                  12573  mam2py-din-imo-bsdap12524  bimhs-mepipe2-oem-nbetameph        12574  dhim-24thiz-emo-bphabs12525  im-pipmea-cpro-aspbzla             12575  thpym-eta-eoco-dfzdap12526  bhs-eta-napo-bhsdap                12576  am2py-25thiman2-fo-aspibua12527  2pmhs-amo2-mes-bphabs              12577  impy-pipmea-no2-bhsdap12528  am4py-pyma2-cpro-bnsdap            12578  am4py-m25thizman2-meto-12529  hythpym-din-napo-zdabs                    bphabs12530  dhim-am3-oem-nbetameph             12579  bim-mepipe2-oem-nzdab12531  me2py-3diaz-fo-betadcph            12580  piraz-dimen-oem-betaet12532  2pmhs-tetras-imo-thizzdap          12581  morhs-mea2s-imo-glubzla12533  bim-m24thizman2-emo-glupha         12582  thpym-thizn-chexo-zdab12534  pippy-props-no1-mezphe             12583  2py-am3diaz-napo-zdab12535  bhs-pipa-eoco-oxal                 12584  z-amn2-meo-bnsdap12536  mam2py-dimen-no2-glubzla           12585  pyrhs-trias-5amo-betadcph12537  hythpym-pipa-no2-bsdap             12586  cl3pyme-24thiz-meo-mezphe12538  impy-pymea-napo-betadcph           12587  thpym-am3-sem-nbetapy12539  4pmhs-mepipe2-oem-nzdap            12588  pyr-mepazin-no1-glyzdap12540  2py-mepipen2-mes-bphabs            12589  z-dis-hso-bsdap12541  bhs-dimephmem-oem-zdapee           12590  thpym-dimephmep-mes-bhsdab12542  bhs-edian2-no2-zdap                12591  bimhs-amo2-chexo-bhsdap12543  2py-amo2-men-bnsdap                12592  impy-25oxman2-ocho-asppha12544  nmhs-butn-no1-ibsdap               12593  dhim-pazin-fo-osdap12545  pippy-n24thiman-emo-glupha         12594  thpym-mepipe-oem-bnsdap12546  bim-3diaz-imo-betapy               12595  dmbim-pipmea-hso-zdap12547  n2py-mepipen2-no2-bphabs           12596  mam2py-mea-5pho-betainyl12548  impy-amn2-meo-psdab                12597  impy-mepipe-eoco-betapy12549  morhs-pnymea-pheo-bhsdab           12598  am4py-mepipe-eoco-oxal12550  imhs-edian2-no1-bhsdap             12599  2py-pazin-ocho-psdap12551  phpip-m24thizman2-eoco-            12600  hythpym-amo3-imo-asppha
   glupha                             12601  2py-pipmea-ocho-aspibua12552  piraz-n2nme2n-5pho-zdabs           12602  amim-dio-meo-dfzdap12603  prhs-mepipen2-no1-betapy           12654  nim-24thizman2-mmen-aspbzla12604  2py-trias-imo-glyzdap              12655  nmor-dimephmem-oem-aspbzla12605  bim-3pazin-meo-bhsdab              12656  mam2py-24thiz-paco-psdap12606  2py-props-meo-psdap                12657  bim-25thiman2-ocho-bhsdap12607  pippy-dimephmep-eoco-dfzdap        12658  cl3pyme-mea2s-ocho-psdab12608  am2py-pymea-oem-glyzdap            12659  gua-25thiman2-imo-zdap12609  fthpym-25oxman2-no1-csdap          12660  bimhs-butn-daco-dfzdap12610  mam2py-m25thiz-fo-zdap             12661  impy-pymea-imo-aspbzla12611  im-pentas-no1-zdabs                12662  piraz-tetradi-imo-glyzdap12612  mam2py-diphmep-5pho-ppsdap         12663  thpym-din-meteto-bsdap12613  phpip-n2o2n-imo-dfzdap             12664  imhs-pnymea-imo-glubzla12614  am-mepipe-imo-bsdap                12665  bim-mepipe-mes-bsdap12615  imhs-tridi-napo-aspbzla            12666  mepip-mepazin-mes-asppha12616  dhim-am3-sem-nbetabnaphth          12667  me-indan2-meo-zdabs12617  pyraz-am3-oem-npsdap               12668  me2py-dimephmem-meo-mezphe12618  hythpym-ams2-chexo-bnsdap          12669  prhs-24thiman2-mes-psdab12619  thpym-amn2-5pho-aspbzla            12670  bhs-dimephmem-pro-betapy12620  imhs-dimephmep-no1-betainyl        12671  bzl-m24thizman2-5amo-aspbzla12621  morhs-props-4pho-glyzdap           12672  2py-amo2-5pho-betadcph12622  impy-m25oxman2-5amo-bhsdab         12673  dmam-diphmem-no1-asppha12623  me2py-dimephmep-men-zdab           12674  me2py-m25thiz-cno-asppha12624  bz-mepipe2-oem-nzdab               12675  impy-dimen-imo-bphabs12625  dmbim-dimen-oem-psdapee            12676  hythpym-24thiman-mes-zdap12626  gua-m24thiz-mmen-bnsdap            12677  mam2py-m24thizman2-meo-bsdap12627  mam2py-hexas-ocho-bhsdab           12678  am4py-amo2-meo-aspaba12628  imhs-edian2-meo-betapy             12679  thpym-m25thiz-meo-betapy12629  hythpym-din-ocho-betainyl          12680  impy-din-fo-psdab12630  mam2py-propn-men-bhsdap            12681  pippy-am2-oem-nbetapy12631  thpym-25thiz-4pho-tsdap            12682  chmhs-props-fo-psdab12632  chmhs-ams3-napo-bphabs             12683  me2py-pyma2-ocho-ppsdap12633  pippy-m25thiz-imo-betadcph         12684  bhs-tetradi-napo-thizzdap12634  tolhs-pipmea-fo-psdap              12685  dhim-tridi-eoco-psdab12635  bimhs-diphmep-5amo-betadcph        12686  hythpym-ams2-mes-betainyl12636  z-amn3-eoco-dfzdap                 12687  thpym-24thizman2-peo-dfzdap12637  bhs-pymea-daco-aspibua             12688  am-amn2-imo-betapy12638  dhim-dimephmem-mommo-zlys          12689  pippy-din-no2-aspaba12639  mam2py-24thiman2-emo-bphabs        12690  am2py-diphmem-5amo-zlys12640  thpym-pazin-oem-zdap               12691  2py-2pazin-pyo-betainyl12641  2py-pnymea-eoco-bhsdab             12692  ppy-edian2-oem-glyzdap12642  imhs-mepazin-mes-dfzdap            12693  mam2py-m24thizman2-oem-12643  bim-amn3-5pho-betainyl                    glyzdap12644  ppy-amn3-5pho-zdab                 12694  amim-25thizman2-aco-zlys12645  dhim-am2-oem-npsdap                12695  impy-tetradi-meo-asppha12646  thpym-edia2-oem-nzdap              12696  menim-pentas-fo-zorn12647  pippy-am2-oem-npsdap               12697  impy-edian2-meto-zdabs12648  2pmhs-din-aco-psdapee              12698  2py-m24thizman2-chexo-12649  dmbim-m24thiman2-mommo-                   aspbzla
   bhsdab                             12699  n2py-pipmes-eoco-csdap12650  2pmhs-thizn-napo-zdab              12700  piraz-dimephmem-ocho-bsdap12651  bhs-24thizman2-men-psdapee         12701  piraz-pipmea-pro-betadcph12652  am2py-dimephmem-emo-zdabs          12702  am2py-mepipe2-oem-npsdap12653  deam-diphmep-napo-zdap             12703  am2py-edian2-chexo-psdap12704  me2py-pipmes-oem-betapy              12753  ec-diphmem-napo-zdabs12705  mam2py-am3-oem-nbeta34-              12754  hythpym-tridi-oem-zdap
   dimeoph                              12755  bhs-mepipe-eoco-bhsdap12706  imhs-pipmea-eoco-glyzdap             12756  n2py-eta-emo-glupha12707  me2py-m25thiz-eoco-aspaba            12757  nmor-diphmem-mommo-betapy12708  2py-mepipe-5pho-zdap                 12758  imhs-pazi2n-oem-zdabs12709  mam2py-24thiz-cno-osdap              12759  thpym-dimephmep-ocho-psdab12710  2pmhs-pymea-eoco-asppha              12760  morhs-24oxman2-cpro-betainyl12711  am2py-edian2-5amo-psdap              12761  dhim-dimen-fo-bsdap12712  imhs-mepipen2-5pho-csdap             12762  impy-m24thizman2-napo-zorn12713  z-pipmea-meteto-zdap                 12763  thpym-m24thiman2-ocho-mezphe12714  dhim-eta2s-men-bphabs                12764  2py-dis-oeto-zdabs12715  mam2py-mepipen2-oeto-bphabs          12765  2py-am3diaz-mes-betaet12716  piraz-tridi-5amo-glubzla             12766  nmor-mepazin-4pho-asppha12717  imhs-24thizman2-chexo-csdap          12767  fthpym-am3diaz-oem-betadcph12718  ec-25thiman2-no2-zdab                12768  impy-din-chexo-zdab12719  ppy-pyma2-oem-bphabs                 12769  bhs-din-5amo-dfzdap12720  dhim-pymea-nmo-dfzdap                12770  pippy-pipa-cpro-bsdap12721  dhim-diphmem-no2-csdap               12771  am-pymea-nmo-psdap12722  ec-tridi-oem-betadcph                12772  2py-pazin-mes-zdab12723  bim-mea2s-mes-glupha                 12773  impy-pipmea-5amo-glyzdap12724  bim-pazin-no1-zdab                   12774  pippy-m25thiz-eoco-aspibua12725  2py-amn2-oem-zdab                    12775  piraz-amo2-meto-psdab12726  nmor-m24thiz-chexo-psdab             12776  piraz-hexadi-5amo-dfzdap12727  pyrhs-amo2-emo-zdap                  12777  tolhs-pymea-napo-csdap12728  phhs-24thizman2-emo-psdap            12778  mam2py-pipa-oem-mezphe12729  hythpym-m25thizman2-                 12779  am4py-tetradi-5pho-glyzdap
   meo-csdap                            12780  prhs-trias-oeto-bsdap12730  me2py-am2-oem-nzdab                  12781  bim-am2-sem-nbeta34dimeoph12731  bimhs-pyma2-cno-aspibua              12782  pippy-mepipe-cpro-aspbzla12732  gua-dimephmem-napo-psdab             12783  am2py-trias-daco-psdab12733  deam-mepipen2-5pho-bhsdab            12784  hythpym-hexas-5pho-zdabs12734  imhs-eta-no2-psdap                   12785  hythpym-pymea-baeo-ppsdap12735  me-ams2-no2-dfzdap                   12786  morhs-thizn-no2-glyzdap12736  2py-edian2-meo-bsdap                 12787  bimhs-dipch-aco-tsdap12737  am2py-dis-men-psdapee                12788  bim-diphmep-no2-bhsdab12738  am2py-dis-chexo-zdapee               12789  imhs-eta-eoco-zdap12739  pippy-mepazin-ocho-bhsdap            12790  hythpym-m25thizman2-5pho-12740  pyrhs-din-ocho-bsdap                        betainyl12741  thpym-24thizman2-no1-                12791  pippy-mepipen2-fo-psdab
   betainyl                             12792  bim-amo2-eoco-dfzdap12742  nim-pazin-5amo-aspibua               12793  am2py-pipa-mmen-aspibua12743  am-mepipe2-sem-nbetabnaphth          12794  2py-m25thiz-eoco-mezphe12744  am2py-pipa-men-asppha                12795  thpym-dimephmep-no1-betainyl12745  am2py-dimephmep-imo-zdap             12796  imhs-pipa-ocho-psdab12746  tolhs-mepipen2-chexo-glyzdap         12797  am2py-amo3-chexo-zdab12747  pyraz-diphmem-chexo-zdabs            12798  mepip-m24thizman2-pro-csdap12748  bim-amn2-meo-psdab                   12799  amim-m25thizman2-mmen-zlys12749  menim-dimephmep-5pho-osdap           12800  dhim-edian2-mommo-bhsdab12750  edothpym-pipmea-meo-zdabs            12801  bim-24thiz-oem-bnsdap12751  ppy-mepipen2-oem-bhsdab              12802  impy-m24thizman2-napo-12752  amim-m25thizman2-ocho-zdab                  thizzdap12803  mam2py-m24thizman2-                 12853  me2py-m24thizman2-emo-asppha
   men-ppsdap                          12854  dhim-m24thiman2-meo-betadcph12804  pippy-din-fo-psdap                  12855  bim-edian2-napo-betapy12805  am4py-m25thizman2-chexo-            12856  bhs-edian2-4pho-bphabs
   mezphe                              12857  dmbim-amo2-no2-betapy12806  phpip-pnymea-men-asppha             12858  bimhs-24thizman2-imo-glyzdap12807  me-dimephmep-imo-psdab              12859  piraz-pipa-eoco-bhsdap12808  nmhs-m24thiman2-fo-zdabs            12860  thpym-mepazin-men-bnsdap12809  emnim-dimephmep-eoco-aspibua        12861  edothpym-pipa-mecpo-dfzdap12810  bim-eta-ocho-bhsdap                 12862  2pmhs-pentadi-eoco-bphabs12811  menim-diphmep-baeo-zdab             12863  dhim-din-no1-psdab12812  impy-m25thiz-mes-csdap              12864  bimhs-edian2-oeto-bhsdab12813  pippy-dimephmep-napo-bhsdap         12865  pyrhs-pnymea-mes-dfzdap12814  edothpym-m25thiz-cno-bsdap          12866  bhs-mepipe-meo-zdap12815  mam2py-edian2-cnmo-betainyl         12867  2py-2pazin-baeo-glyzdap12816  4pmhs-pipmeo-no1-aspbzla            12868  bhs-diphmep-imo-zdab12817  am2py-24thizman2-eoco-csdap         12869  mam2py-props-men-betainyl12818  impy-thizn-chexo-psdap              12870  hythpym-eta-eoco-thizzdap12819  ec-tetradi-nmo-bhsdab               12871  pyrhs-mepipe-baeo-zdab12820  morhs-amn3-mmen-bhsdab              12872  bhs-eta-meo-bhsdap12821  hythpym-amo2-imo-psdab              12873  hythpym-ams2-paco-glyzdap12822  me2py-m25thiz-5pho-zorn             12874  imhs-mepipe-ocho-zdab12823  mepip-amo2-oem-bphabs               12875  am2py-butn-5amo-bsdap12824  mam2py-propa2s-fo-glupha            12876  nmor-mepipe2-oem-npsdap12825  tolhs-24thizman2-hso-bhsdab         12877  2py-pazin-eoco-zdab12826  mam2py-amn2-eoco-dfzdap             12878  am2py-edian2-oem-mezphe12827  imhs-pymea-oem-csdap                12879  mam2py-25thiz-5pho-mezphe12828  thpym-eta-no1-bnsdap                12880  impy-indan2-no1-psdap12829  pyr-thizn-chexo-aspibua             12881  thpym-pazin-no1-zdab12830  imhs-mepipe-ocho-betapy             12882  bimhs-amo2-napo-bnsdap12831  bhs-dimen-5amo-bnsdap               12883  impy-am3-oem-nbetapy12832  chmhs-amn3-eoco-aspbzla             12884  me2py-24oxman2-oem-mezphe12833  piraz-m25thiz-mes-dfzdap            12885  amthiaz-dimephmem-fo-betapy12834  amim-m24thizman2-oem-aspibua        12886  bim-mepipe-5pho-bhsdap12835  2py-tetradi-napo-ppsdap             12887  2pm%s-24thiz-men-bhsdap12836  dhim-m24oxman2-men-bnsdap           12888  am4py-dipch-imo-ibsdap12837  2py-pazin-mes-bsdap                 12889  me2py-din-oem-bnsdap12838  chmhs-dimen-mes-dfzdap              12890  2py-25thiman2-cno-bhsdab12839  npip-amo2-oeto-zdabs                12891  imhs-eta-5pho-bhsdap12840  hythpym-mepazin-napo-dfzdap         12892  dhim-am3diaz-mes-zlys12841  bhs-m25thiz-pheo-aspibua            12893  mam2py-amn2-men-zdap12842  me2py-24thizman2-5pho-dfzdap        12894  z-m25oxman2-imo-bnsdap12843  hythpym-dimen-5amo-bnsdap           12895  dhim-mepipen2-chexo-bphabs12844  phpip-dimephmep-mes-osdap           12896  dpam-mepazin-ocho-zdab12845  bim-eta-no1-psdap                   12897  2py-mepipe-no2-psdap12846  bimhs-mepipen2-5pho-ppsdap          12898  phhs-m25thiz-no2-zdabs12847  mam2py-dimephmem-men-zdap           12899  am4py-pipmea-men-ibsdap12848  bimhs-ams2-paco-betainyl            12900  tolhs-pnymea-oem-asppha12849  bim-mepipe-oem-psdab                12901  bim-pazin-meteto-csdap12850  imhs-amn3-eoco-zdap                 12902  4pmhs-mepazin-5pho-aspibua12851  piraz-mepipe-napo-bhsdab            12903  tolhs-mepipe-meo-betadcph12852  hythpym-pipmes-imo-zdabs            12904  dpam-pymea-paco-betainyl12905  amim-n2nme2n-4amo-psdap           12956  mepip-eta-chexo-zdab12906  bim-eta-meto-aspibua              12957  4pmhs-pyma2-5pho-betadcph12907  bhs-pazin-5pho-psdap              12958  piraz-diphmem-oem-asppha12908  amthiaz-edia2-oem-nzdab           12959  dhim-am3diaz-meo-zdab12909  thpym-eta-cnmo-bsdap              12960  bimhs-pyma2-cnmo-bsdap12910  bhs-amn3-paco-psdab               12961  imhs-mepipen2-ocho-betapy12911  me2py-m24thiz-oeto-glyzdap        12962  bzl-pazin-5amo-tsdap12912  hythpym-m24thizman2-mes-          12963  2py-amn2-oem-psdap
   bnsdap                            12964  dhim-am2-sem-npsdap12913  hythpym-pazin-oeto-betainyl       12965  bhs-dimephmem-imo-csdap12914  thpym-amn2-no2-zdab               12966  pippy-pyma2-men-aspbzla12915  thpym-eta-eoco-bnsdap             12967  nim-mepipe-5pho-zdab12916  imhs-pipmea-men-csdap             12968  amthiaz-thizn-emo-thizzdap12917  hythpym-diphmep-men-aspibua       12969  impy-m24thizman2-aco-12918  bim-edian2-5pho-bsdap                    betadcph12919  moegua-thizn-meo-zdap             12970  mam2py-m25thiz-eoco-csdap12920  pippy-amo2-5pho-bhsdap            12971  me2py-thizn-chexo-betainyl12921  pippy-24thizman2-oem-bphabs       12972  imhs-pyma2-cpeo-glyzdap12922  hythpym-pymea-imo-mezphe          12973  dmam-tridi-chexo-psdab12923  hythpym-mepazin-no1-betapy        12974  nmor-ams2-napo-zdap12924  am2py-props-cnmo-betapy           12975  hythpym-din-no2-psdap12925  me2py-m24thiman2-fo-ibsdap        12976  piraz-tridi-fo-bhsdab12926  piraz-am3diaz-napo-aspbzla        12977  am2py-25thiman2-imo-oxal12927  mam2py-mepipen2-oem-psdab         12978  chhs-eta-cpro-mezphe12928  me-tridi-no2-zdab                 12979  mam2py-ams2-no2-betainyl12929  dmbim-diphmem-eoco-zdabs          12980  pippy-24thiz-chexo-zlys12930  piraz-ams2-men-mezphe             12981  n2py-24thiz-men-bhsdap12931  amim-dis-mes-betadcph             12982  npip-m25thiz-oem-betadcph12932  piraz-pnymea-mmen-bhsdap          12983  dhim-edian2-no2-bhsdab12933  bim-25oxman2-cpeo-bphabs          12984  edothpym-m25thiz-oem-aspbzla12934  z-24thizman2-no2-betapy           12985  me2py-mea2s-imo-bsdap12935  bimhs-am3diaz-5amo-zdabs          12986  ppy-mepipen2-no1-betainyl12936  imhs-amn2-eoco-psdap              12987  bim-amn2-oem-psdab12937  me2py-hexadi-emo-bnsdap           12988  mepip-ams3-no1-betainyl12938  mam2py-amn3-5amo-bnsdap           12989  imhs-eta-oem-psdap12939  emnim-mepazin-mes-betadcph        12990  bim-eta-oem-psdap12940  bimhs-diphmep-napo-bphabs         12991  piraz-dimephmem-meo-asppha12941  am-n2nme2n-mecpo-bsdap            12992  piraz-eta-5pho-zdabs12942  pippy-am3-oem-nbetapy             12993  bhs-eta-5pho-bnsdap12943  mam2py-amn2-mes-zdab              12994  me-edian2-5amo-glubzla12944  bim-am3-sem-nbetameph             12995  hythpym-trias-cno-aspbzla12945  piraz-diphmep-5pho-psdapee        12996  am2py-mepipen2-no2-betaet12946  impy-edian2-oeto-psdap            12997  pyr-24thiz-imo-glyzdap12947  me-pnymea-5amo-bhsdap             12998  imhs-amn2-mes-betapy12948  bim-edian2-no2-betapy             12999  dhim-pentadi-fo-csdap12949  bhs-trias-oem-zdap                13000  me-edian2-chexo-betadcph12950  bhs-amn2-mes-bhsdap               13001  bhs-n24thiman-mes-zdabs12951  bimhs-trias-no2-asppha            13002  bimhs-dis-emo-dfzdap12952  2py-tridi-hso-glupha              13003  mepip-m25thizman2-no2-mezphe12953  n2py-24thiz-pheo-oxal             13004  hythpym-tridi-no2-betainyl12954  gua-dimen-mommo-asppha            13005  piraz-thizn-no1-bsdap12955  impy-pnymea-pheo-csdap            13006  npip-dimephmem-ocho-zdap13007    bim-din-eoco-bsdap              13058    amim-ams2-men-dfzdap13008    amim-m25thiz-hso-betadcph       13059    tolhs-pnymea-no1-aspibua13009    dpam-pyma2-men-psdap            13060    dmthpym-pymea-emo-zdapee13010    mam2py-25thizman2-men-zorn      13061    bim-edian2-eoco-betapy13011    bim-pipa-chexo-betadcph         13062    hythpym-amn2-mmen-zdap13012    bim-eta-5pho-bsdap              13063    bim-24thiz-cpeo-psdab13013    2py-m24thiman2-imo-bhsdab       13064    menim-amn2-men-mezphe13014    imhs-mepazin-pheo-zdab          13065    bim-mepazin-5amo-ppsdap13015    imhs-pazin-no1-bhsdap           13066    me-pipa-4amo-psdap13016    bimhs-amo2-imo-aspaba           13067    bimhs-edian2-no1-aspibua13017    hythpym-dio-emo-csdap           13068    pippy-tetradi-oem-aspbzla13018    amim-dimen-chexo-csdap          13069    bhs-propa2s-5amo-zdabs13019    bim-m25thiz-emo-dfzdap          13070    bim-pnymea-napo-zlys13020    pippy-am2-oem-nzdab             13071    pippy-pipa-napo-zdap13021    dhim-pipmea-5pho-glyzdap        13072    dhim-edian2-meteto-ppsdap13022    ppy-eta2s-5pho-bhsdab           13073    bhs-pazin-no2-zdab13023    dhim-24thizman2-nmo-bhsdab      13074    am2py-thizo-emo-zdabs13024    dmam-dimen-fo-glubzla           13075    bim-edian2-oem-bhsdap13025    amthiaz-amo2-ocho-bphabs        13076    ibhs-24oxman2-imo-bnsdap13026    tolhs-tetradi-meto-thizzdap     13077    hythpym-thizo-pro-asppha13027    dhim-edian2-men-zdab            13078    pippy-pipa-meto-bhsdab13028    dhim-amo3-oem-glyzdap           13079    bhs-indan2-5amo-glubzla13029    pyr-butn-oem-zdab               13080    pippy-pymea-5pho-dfzdap13030    amim-mepipen2-pheo-bnsdap       13081    cl3pyme-pnymea-men-zdap13031    thpym-pipmea-no2-mezphe         13082    impy-dis-mes-bnsdap13032    2py-trias-emo-csdap             13083    thpym-eta-napo-glyzdap13033    chmhs-pazin-no2-psdap           13084    bim-butn-fo-psdap13034    amim-25thizman2-cpeo-glyzdap    13085    bimhs-ams2-no2-mezphe13035    n2py-tetradi-no1-bnsdap         13086    am2py-mepipe-ocho-zdabs13036    hythpym-ms-5pho-glupha          13087    me2py-tetradi-5amo-zdab13037    imhs-amn2-no2-bhsdap            13088    am4py-eta-5amo-dfzdap13038    imhs-diphmem-mmen-glyzdap       13089    hythpym-25oxman2-hso-zlys13039    amim-m24thizman2-ocho-bhsdap    13090    gua-pnymea-hso-aspbzla13040    dhim-mepipe-5amo-aspaba         13091    dhim-eta-paco-psdab13041    menim-ams2-cpeo-aval            13092    emnim-pymea-napo-bphabs13042    pippy-butn-daco-bsdap           13093    2pmhs-mepipen2-eoco-glupha13043    am2py-dis-imo-aspbzla           13094    cl3pyme-pazi2n-chexo-zdap13044    dhim-25thizman2-5amo-glyzdap    13095    amthiaz-am3-oem-nzdap13045    mam2py-eta-imo-zdap             13096    thpym-amn2-eoco-zdap13046    impy-amn3-emo-zdabs             13097    bhs-n2nme2n-5amo-zdapee13047    bhs-dis-mmen-betadcph           13098    2py-mepipen2-napo-aspibua13048    bhs-pipmes-napo-glyzdap         13099    mam2py-pipa-cnmo-aspbzla13049    dmthpym-tetradi-pheo-csdap      13100    imhs-tetradi-chexo-mezphe13050    me2py-m24thiz-emo-bhsdab        13101    hythpym-amo2-no2-zdabs13051    bhs-amn2-no1-bnsdap             13102    bhs-amn2-5pho-betapy13052    imhs-m25thizman2-chexo-         13103    am2py-trias-aco-psdapee
     bphabs                          13104    dhim-3pazin-nmo-bnsdap13053    bimhs-amn2-fo-bhsdap            13105    bim-edian2-no1-psdab13054    imhs-dimen-emo-glyzdap          13106    am2py-pazi2n-ocho-glyzdap13055    bimhs-eta-oem-bhsdap            13107    dhim-pipmea-oem-zorn13056    chhs-25thiman2-fo-mezphe        13108    gua-din-meto-aspibua13057    bimhs-3diaz-hapo-zdap           13109    bimhs-pentadi-5amo-bnsdap13110    mepip-pymea-imo-asppha        13161    bimhs-indan2-meo-zdap13111    dpam-m25thiz-napo-bsdap       13162    thpym-eta-5pho-bsdap13112    imhs-diphmem-napo-thizzdap    13163    bimhs-mepipen2-5amo-aspbzla13113    imhs-m24thizman2-mes-psdab    13164    z-m25thiz-cnmo-thizzdap13114    thpym-25oxman2-fo-bsdap       13165    2py-24thiz-meo-asppha13115    bimhs-thizn-meteto-glyzdap    13166    thpym-edia2-sem-nbetameph13116    z-tetradi-chexo-csdap         13167    bim-mepipe-eoco-psdap13117    mam2py-24oxman2-no2-bphabs    13168    amim-butn-no1-aspibua13118    am2py-pymea-mes-dfzdap        13169    mam2py-m24thizman2-mecpo-13119    2py-amn3-napo-zdap                     glyzdap13120    bhs-amn2-meo-psdap            13170    bim-dis-nmo-bhsdap13121    am2py-tetras-meo-psdap        13171    mam2py-amo3-chexo-csdap13122    amthiaz-24thiz-mes-aspbzla    13172    hythpym-amn3-chexo-glupha13123    bhs-n2nme2n-no1-aspbzla       13173    fthpym-25thiman2-men-13124    im-diphmem-meo-betaet                  betadcph13125    imhs-tridi-oem-ppsdap         13174    bim-diphmep-no2-zdap13126    imhs-pazin-daco-bsdap         13175    pippy-amo2-4amo-glyzdap13127    bhs-eta-no1-bsdap             13176    hythpym-pazi2n-no2-betapy13128    pyraz-pazin-emo-betainyl      13177    dhim-trias-imo-dfzdap13129    thpym-din-mommo-mezphe        13178    bimhs-thizn-5pho-betapy13130    ibhs-thizn-chexo-bsdap        13179    me2py-pazin-mecpo-bhsdab13131    menim-dis-oem-zdap            13180    npip-pnymea-mes-asppha13132    bhs-amn2-no2-bnsdap           13181    dhim-pnymea-fo-dfzdap13133    bim-amn2-mecpo-dfzdap         13182    amim-pipmea-4pho-bhsdap13134    phpip-dis-5amo-zdap           13183    bzl-24thizman2-imo-bnsdap13135    hythpym-dimephmem-oem-        13184    im-m25thiz-imo-bhsdap
     aspibua                       13185    amim-25thizman2-emo-osdap13136    imhs-pazin-cno-csdap          13186    pippy-pazi2n-fo-psdapee13137    hythpym-diphmem-oem-bphabs    13187    ppy-mepipe-mommo-psdab13138    amim-trias-peo-psdab          13188    bhs-m24thizman2-no2-mezphe13139    z-hexas-cpeo-zdap             13189    2py-dich-5pho-glyzdap13140    dhim-amn2-no2-zdab            13190    mam2py-pipa-meo-betainyl13141    am2py-25oxman2-4pho-psdapee   13191    im-am3-oem-nbetapy13142    am2py-amo2-pheo-bsdap         13192    menim-pymea-meo-betadcph13143    bhs-thizn-meteto-psdap        13193    impy-24thiz-cnmo-psdab13144    bim-pymea-ocho-zdabs          13194    bhs-25oxman2-cno-glyzdap13145    bimhs-diphmep-men-glubzla     13195    me2py-pymea-daco-zlys13146    me2py-amo2-chexo-zdapee       13196    bhs-pazin-oem-zdab13147    mam2py-mepazin-chexo-bphabs   13197    nim-mepazin-men-glyzdap13148    pippy-amn2-no2-zdabs          13198    thpym-ams2-chexo-betainyl13149    bhs-edian2-no2-psdap          13199    amthiaz-propn-men-zdab13150    dmthpym-3diaz-men-betadcph    13200    impy-amo3-mes-bphabs13151    2pmhs-amo3-paco-mezphe        13201    2py-m25oxman2-mmen-zdapee13152    me2py-amn3-napo-betadcph      13202    thpym-dimephmep-imo-zdap13153    dmbim-pipmea-meo-psdapee      13203    mam2py-am3diaz-chexo-zdap13154    moegua-diaz-oem-osdap         13204    bz-butn-no1-zdap13155    phhs-ms-4amo-zdab             13205    bim-mepipe-no2-betapy13156    mam2py-dipch-meteto-dfzdap    13206    npip-edia2-oem-nbeta34-13157    ppy-am3-sem-nzdap                      dimeoph13158    bhs-mepazin-men-aspbzla       13207    thpym-edian2-oem-betapy13159    bhs-pazin-no1-betapy          13208    npip-mepipe-meo-asppha13160    bhs-amn3-no1-bhsdap           13209    imhs-pazi2n-men-zdap13210    me2py-din-mes-zdab            13261    am4py-m25thizman2-imo-bhsdap13211    hythpym-edian2-no2-betapy     13262    am2py-pipa-oeto-betainyl13212    nmhs-pazin-eoco-psdab         13263    pyraz-amn3-nmo-zdabs13213    bhs-dimen-eoco-psdab          13264    bim-edian2-5pho-betapy13214    me2py-24thiz-ocho-asppha      13265    2py-pazin-no2-psdab13215    imhs-din-mecpo-betadcph       13266    2py-pazin-5pho-zdap13216    amim-dimephmem-napo-psdab     13267    deam-24thizman2-nmo-betainyl13217    impy-m25oxman2-fo-csdap       13268    phhs-dimephmem-cpro-bhsdab13218    bimhs-dimephmem-5amo-bhsdap   13269    fthpym-din-meto-betadcph13219    hythpym-m25thiman2-no1-       13270    bimhs-pnymea-5amo-aspaba
     dfzdap                        13271    imhs-eta-cpro-mezphe13220    bim-24thizman2-5amo-psdab     13272    thpym-tridi-mes-aspbzla13221    bhs-pazin-5pho-zdab           13273    2pmhs-mepipe-5pho-betaet13222    dpam-dimephmem-5pho-bhsdab    13274    bhs-amn2-mes-bsdap13223    imhs-pazin-mes-betapy         13275    thpym-25thiman2-no2-dfzdap13224    2py-pazin-5amo-csdap          13276    pippy-pymea-no2-zdapee13225    im-dimephmep-5amo-ppsdap      13277    me2py-thizn-emo-bhsdap13226    impy-thizn-5pho-aspbzla       13278    cl3pyme-dimephmep-emo-psdab13227    imhs-din-oem-oxal             13279    piraz-thizn-5pho-betadcph13228    pippy-diphmem-chexo-zdap      13280    mam2py-amo2-paco-psdapee13229    bim-am3diaz-5amo-bnsdap       13281    dhim-amn2-imo-tsdap13230    2py-3diaz-ocho-mezphe         13282    me2py-25oxman2-hso-bsdap13231    dhim-dipch-cno-mezphe         13283    emnim-thizn-meo-zdapee13232    thpym-2pazin-mmen-ibsdap      13284    am2py-dio-cnmo-bhsdab13233    amim-diphmep-5pho-bhsdab      13285    thpym-pazin-no1-bhsdap13234    dhim-dimen-daco-bhsdab        13286    thpym-trias-eoco-betapy13235    ppy-diphmem-meo-bphabs        13287    pippy-pnymea-cnmo-betapy13236    dhim-thizo-fo-bnsdap          13288    2py-dis-emo-zdapee13237    bimhs-dimephmep-oeto-zdap     13289    phhs-n2o2n-meo-aspbzla13238    bim-mepipe-baeo-psdap         13290    4pmhs-m25thiz-chexo-zorn13239    mam2py-amn3-fo-glyzdap        13291    pyrhs-eta-no1-zdab13240    2py-25thiman2-eoco-dfzdap     13292    deam-dis-chexo-bhsdab13241    bimhs-pazin-fo-zdab           13293    me-edian2-no2-bnsdap13242    mam2py-pyma2-fo-psdab         13294    pippy-pipmea-fo-aspibua13243    amim-25oxman2-cno-zdap        13295    bhs-pipmea-fo-aspaba13244    impy-pazin-eoco-aspbzla       13296    fthpym-pipmeo-eoco-psdap13245    me2py-mepazin-oem-asppha      13297    chmhs-diphmem-chexo-csdap13246    nmhs-mepipe-peo-aspbzla       13298    imhs-eta-oem-psdab13247    hythpym-mepazin-cpeo-aspaba   13299    am4py-pazin-men-zdab13248    thpym-24thiman-5pho-bhsdap    13300    piraz-m24thizman2-5amo-psdap13249    am-25oxman2-ocho-asppha       13301    2pmhs-dimen-oeto-betapy13250    nmhs-ams3-cpeo-psdab          13302    menim-dimen-chexo-psdapee13251    hythpym-dimephmem-hso-bphabs  13303    thpym-mepazin-5pho-psdab13252    nmor-m25oxman2-cpro-bphabs    13304    menim-edian2-peo-ppsdap13253    bhs-pyma2-ocho-oxal           13305    impy-edia2-oem-zdab13254    piraz-mepipen2-men-mezphe     13306    chmhs-diphmep-no2-mezphe13255    2py-dimephmep-4pho-aspbzla    13307    me-m25thiz-5pho-betadcph13256    phhs-amn2-men-aspbzla         13308    bhs-am2-sem-nbeta34dimeoph13257    bhs-tridi-mes-bnsdap          13309    bzl-mepipe2-oem-nzdab13258    ec-tridi-mes-glubzla          13310    nim-m25thizman2-men-osdap13259    am2py-dipch-paco-betadcph     13311    dhim-mepipe-oem-zdabs13260    cl3pyme-m25thiz-pheo-bsdap    13312    mam2py-amo2-men-psdap13313    impy-pnymea-mommo-aspbzla       13364    bhs-amn3-5pho-zdap13314    amim-24oxman2-no2-betapy        13365    dhim-eta-men-bsdap13315    npip-dis-oem-zdap               13366    pippy-dimephmem-baeo-zdap13316    pippy-diphmep-napo-bsdap        13367    imhs-dimen-emo-glyzdap13317    moegua-m25thiz-ocho-betadcph    13368    amim-ams3-fo-glupha13318    pyrhs-propa2s-mes-csdap         13369    edothpym-pnymea-mes-betainyl13319    bhs-m25thiz-chexo-aspibua       13370    mam2py-n24thiman-no2-betaet13320    thpym-25oxman2-meteto-zdap      13371    hythpym-pipa-mmen-bnsdap13321    bhs-edian2-meo-bhsdap           13372    bim-din-imo-zdap13322    bim-3pazin-mecpo-oxal           13373    bhs-thizn-no2-bhsdab13323    mam2py-amn2-emo-zdab            13374    bimhs-amn3-imo-zdap13324    bhs-eta-no1-betapy              13375    dhim-pipa-fo-zlys13325    mam2py-diphmem-chexo-zdab       13376    am2py-pyma2-4pho-betainyl13326    pippy-25thiman2-eoco-asppha     13377    phpip-pipa-meo-dfzdap13327    imhs-eta-no1-betapy             13378    edothpym-tetradi-fo-asppha13328    thpym-ams2-4pho-zdap            13379    bimhs-mepazin-fo-thizzdap13329    dhim-eta-fo-psdab               13380    2py-edia2-oem-nbetameph13330    dhim-tridi-mes-betapy           13381    me2py-dimephmem-imo-psdap13331    amim-dimephmep-emo-dfzdap       13382    2py-diphmep-pyo-bhsdap13332    edothpym-pazin-mes-betaet       13383    amim-24thiman2-emo-psdab13333    am-25thiman2-fo-glyzdap         13384    2pmhs-tridi-eoco-aspibua13334    hythpym-trias-5amo-glyzdap      13385    me2py-pyma2-eoco-csdap13335    thpym-eta-mes-betapy            13386    bim-edian2-meo-bnsdap13336    deam-pazin-fo-betapy            13387    2pmhs-tridi-imo-aspbzla13337    piraz-mepipen2-4amo-dfzdap      13388    npip-thizn-meto-bhsdap13338    hythpym-pazi2n-pro-bhsdab       13389    moegua-ams2-no1-psdab13339    impy-butn-nmo-bphabs            13390    imhs-dimephmep-oem-aspaba13340    am2py-mepipe-imo-zorn           13391    2py-dio-5pho-bphabs13341    thpym-eta-meo-bhsdap            13392    amthiaz-tridi-chexo-psdap13342    imhs-pazin-meo-psdap            13393    2py-pnymea-meo-zdap13343    bim-m24thizman2-mecpo-bnsdap    13394    thpym-pazin-5pho-psdap13344    dhim-pazin-men-ibsdap           13395    2py-mepipen2-imo-csdap13345    am2py-24thiman-chexo-zdab       13396    dhim-diphmem-baeo-glupha13346    me2py-din-no1-zdap              13397    nmhs-din-men-bsdap13347    piraz-tetradi-fo-tsdap          13398    amim-dimen-no1-bhsdap13348    impy-dis-5pho-aspbzla           13399    am2py-pnymea-mes-zdabs13349    bim-amo2-mes-csdap              13400    edothpym-24thiz-cpeo-bsdap13350    hythpym-pymea-chexo-asppha      13401    dmbim-trias-meo-betapy13351    emnim-tetras-emo-aspibua        13402    bhs-dimephmep-ocho-betainyl13352    mam2py-pyma2-5pho-betainyl      13403    pyraz-amo2-chexo-ppsdap13353    ppy-amn2-5amo-aspibua           13404    hythpym-dimephmep-men-zdabs13354    deam-2pazin-baeo-zdab           13405    am2py-mepipen2-emo-bsdap13355    thpym-mepipe2-sem-nbetab        13406    am4py-dis-no2-dfzdap
     naphth                          13407    impy-24thiz-no1-aspibua13356    thpym-pyma2-meo-asppha          13408    cl3pyme-pyma2-cpeo-ibsdap13357    mam2py-ams3-imo-psdab           13409    hythpym-butn-cnmo-zdab13358    am2py-diphmep-no1-aspbzla       13410    amim-24thizman2-chexo-13359    amim-pazin-mes-thizzdap                  aspbzla13360    fthpym-pipa-ocho-asppha         13411    imhs-tetradi-meo-psdap13361    tolhs-mepipe-no1-oxal           13412    pippy-dimephmep-pyo-bhsdap13362    emnim-ams2-chexo-psdab          13413    bimhs-pipmes-men-betadcph13363    2py-amn3-no2-bhsdap             13414    mam2py-amn2-no2-glyzdap13415    2py-mepipen2-imo-betadcph       13465    bim-mepipe-ocho-bnsdap13416    fthpym-25thizman2-men-bhsdab    13466    bhs-m25oxman2-mes-psdab13417    2py-eta-mes-psdap               13467    pippy-hexadi-fo-osdap13418    ibhs-din-men-zdap               13468    dmthpym-dimephmep-nmo-13419    bim-mepazin-baeo-bhsdab                  glyzdap13420    imhs-m25oxman2-men-bnsdap       13469    bimhs-tetradi-chexo-betadcph13421    mam2py-25oxman2-pro-zdab        13470    hythpym-dimephmem-meto-psdab13422    bimhs-ams2-aco-aspbzla          13471    pippy-dis-chexo-bhsdab13423    2pmhs-mepipe-eoco-psdab         13472    piraz-m24thizman2-mecpo-13424    me-trias-5pho-zdab                       asppha13425    me2py-24thizman2-no2-dfzdap     13473    2py-pnymea-cpeo-bnsdap13426    impy-tetradi-hso-bhsdap         13474    imhs-mepazin-meo-zdab13427    me2py-thizn-nmo-zdap            13475    prhs-pnymea-mes-zdap13428    me2py-pyma2-5amo-zdab           13476    bhs-pazin-eoco-bnsdap13429    imhs-thizn-imo-psdab            13477    thpym-propa2s-oem-aspibua13430    bim-pazi2n-oem-bhsdab           13478    cl3pyme-diphmem-5pho-zdap13431    dhim-24thiz-meo-psdab           13479    amim-pipa-imo-bnsdap13432    am2py-thizo-oem-zdab            13480    bzl-pnymea-chexo-aspbzla13433    imhs-25oxman2-emo-psdab         13481    ibhs-amo2-5amo-bnsdap13434    mepip-m24thizman2-meteto-       13482    thpym-indan2-emo-zdabs
     bphabs                          13483    me2py-m25thiz-daco-bhsdab13435    ec-diphmep-5pho-bhsdap          13484    pyr-dimephmep-aco-betapy13436    2py-trias-oem-mezphe            13485    4pmhs-tetradi-mes-psdab13437    mepip-n24thiman-5pho-zdabs      13486    dmbim-tridi-eoco-dfzdap13438    thpym-edian2-mes-zdab           13487    bhs-25thiz-aco-aspbzla13439    bhs-edian2-5pho-psdab           13488    impy-pnymea-eoco-zdab13440    impy-indan2-oem-bhsdab          13489    bim-eta-eoco-bhsdap13441    bhs-mepipe-5pho-zdab            13490    dhim-24thiz-5pho-bhsdab13442    pyrhs-m24oxman2-no1-aspibua     13491    nim-am2-oem-nbetapy13443    2py-diphmem-5amo-psdap          13492    dmbim-25thiman2-fo-dfzdap13444    mam2py-diphmem-mecpo-glyzdap    13493    pyrhs-pymea-cno-aspibua13445    piraz-mepazin-men-betaet        13494    me2py-25thiman2-fo-betapy13446    me2py-thizn-fo-thizzdap         13495    piraz-pipmes-5pho-aspbzla13447    amim-pyma2-imo-aspbzla          13496    me2py-pazin-oem-zdab13448    me-amn3-napo-ppsdap             13497    deam-trias-5amo-ibsdap13449    nim-ms-mes-asppha               13498    hythpym-24thiz-5amo-mezphe13450    me2py-mepipe2-sem-nbetab        13499    dhim-amo2-men-csdap
     naphth                          13500    pippy-pipa-5pho-aspbzla13451    mam2py-thizs-aco-betainyl       13501    mam2py-pazin-ocho-aspbzla13452    am2py-pyma2-chexo-dfzdap        13502    chmhs-amo3-paco-bnsdap13453    nmor-pipmea-cnmo-bnsdap         13503    bhs-eta-5pho-psdab13454    imhs-24thizman2-fo-zdap         13504    dhim-trias-meo-csdap13455    pyraz-mepipe-cno-asppha         13505    pippy-mepipe-chexo-asppha13456    ibhs-eta2s-imo-aspbzla          13506    ppy-diphmem-5amo-mezphe13457    imhs-amn2-fo-aval               13507    nmhs-diphmem-mes-betainyl13458    piraz-dimen-5pho-bsdap          13508    imhs-m25thiz-cno-betainyl13459    bim-edia2-oem-nzdap             13509    pyraz-m25oxman2-fo-zdab13460    mam2py-pipa-no2-betainyl        13510    am2py-pazin-pyo-psdap13461    bz-pipmea-ocho-betadcph         13511    2py-mepazin-nmo-betainyl13462    bhs-pazin-oem-bsdap             13512    me2py-24thizman2-imo-bnsdap13463    amim-m25thizman2-men-asppha     13513    fthpym-ms-meto-zdap13464    bhs-eta-imo-mezphe              13514    dhim-ms-mecpo-tsdap13515    hythpym-diphmem-pyo-betapy      13565    bim-mepipe-eoco-bhsdap13516    phhs-dis-4pho-betapy            13566    phpip-din-no1-zdabs13517    ppy-diphmep-meto-bhsdap         13567    am2py-din-ocho-aspaba13518    am4py-m24thizman2-peo-betapy    13568    piraz-mea2s-meo-psdap13519    amim-eta-5amo-bsdap             13569    mam2py-mea-imo-bhsdap13520    menim-pymea-fo-betadcph         13570    2py-mepipe2-sem-nzdab13521    bhs-dipch-men-bnsdap            13571    2py-edian2-ocho-zdap13522    thpym-pnymea-no1-mezphe         13572    pyr-amo3-mes-mezphe13523    dpam-am3-oem-nbetapy            13573    impy-pazin-4pho-tsdap13524    bhs-amn2-ocho-bnsdap            13574    am4py-thizn-mommo-aspaba13525    imhs-edian2-no2-zdap            13575    mepip-amn3-cnmo-glyzdap13526    bzl-24thiman2-meto-asppha       13576    thpym-edian2-meo-psdap13527    hythpym-dis-5amo-bsdap          13577    bim-eta-eoco-zdabs13528    thpym-24thizman2-no1-bhsdap     13578    impy-diphmem-oem-betadcph13529    ibhs-m24oxman2-cpeo-mezphe      13579    hythpym-mepazin-mommo-dfzdap13530    deam-amo2-aco-betainyl          13580    gua-diphmem-eoco-mezphe13531    2py-amn2-no1-bsdap              13581    hythpym-25thiman2-no2-aspaba13532    me-indan2-men-betadcph          13582    morhs-m25thiz-ocho-bphabs13533    mam2py-pazin-mes-psdapee        13583    bimhs-dimephmem-napo-zdabs13534    2pmhs-diphmep-5pho-zdabs        13584    mam2py-3pazin-oeto-betapy13535    bhs-pipmeo-no1-zdabs            13585    nmor-pipa-fo-zdab13536    bim-propn-no2-bnsdap            13586    me2py-am2-sem-nzdab13537    dhim-hexas-meteto-psdab         13587    dhim-ams2-fo-glyzdap13538    imhs-amn2-meo-bhsdap            13588    chmhs-trias-oem-bhsdap13539    pippy-eta2s-5amo-betainyl       13589    emnim-pnymea-no2-bnsdap13540    impy-trias-fo-bhsdap            13590    dmbim-dimephmep-meo-csdap13541    npip-diphmem-chexo-glyzdap      13591    bzl-24thiz-oem-zdab13542    am2py-am2-oem-nzdab             13592    imhs-pazin-pro-glyzdap13543    pyr-trias-5amo-aspibua          13593    bimhs-mepazin-meteto-bnsdap13544    bhs-diphmep-meteto-mezphe       13594    impy-mepipen2-cno-zdap13545    imhs-mepipe-oem-psdab           13595    piraz-pazin-oem-bhsdap13546    phpip-dimephmep-mmen-           13596    thpym-m24oxman2-no1-betainyl
     betadcph                        13597    dpam-thizn-cpro-glupha13547    phpip-amo2-no2-betadcph         13598    mam2py-eta-no1-bphabs13548    morhs-dis-no1-betainyl          13599    fthpym-dimephmep-5pho-betaet13549    chmhs-m24thizman2-men-mezphe    13600    me2py-n24thiman-oem-psdap13550    moegua-m24thizman2-oeto-        13601    impy-m25thiz-fo-psdab
     asppha                          13602    amim-amo3-cpeo-betainyl13551    dhim-ams2-imo-glyzdap           13603    bim-mepipe2-oem-nzdab13552    bhs-hexadi-imo-bhsdab           13604    amim-3pazin-mmen-asppha13553    n2py-amn2-meteto-zdap           13605    amim-m25thiman2-no1-zdap13554    amthiaz-tetras-fo-zdab          13606    am4py-pipa-chexo-psdap13555    piraz-diphmem-emo-psdab         13607    me-trias-oem-bhsdap13556    bhs-pentas-meo-zdabs            13608    pippy-24thizman2-ocho-bhsdab13557    amim-pazin-fo-aspbzla           13609    imhs-mea-5amo-aspbzla13558    nmhs-pnymea-mecpo-psdap         13610    amim-edian2-men-bhsdap13559    piraz-pipmea-mommo-osdap        13611    dhim-pipa-emo-aspibua13560    dhim-n2nme2n-meto-psdap         13612    mepip-24thizman2-oem-13561    menim-dimen-eoco-aspaba                  betadcph13562    pyrhs-edian2-cno-dfzdap         13613    bim-diphmem-mes-aspbzla13563    edothpym-trias-mecpo-betapy     13614    dmthpym-mepipe-men-bnsdap13564    hythpym-amo2-no1-psdab          13615    dhim-ams2-oeto-zdabs13616    bhs-din-men-bsdap               13668    ppy-mepipen2-fo-zlys13617    bim-dimephmep-imo-zdabs         13669    thpym-trias-fo-zdap13618    piraz-24oxman2-oem-aspbzla      13670    bhs-25oxman2-no1-csdap13619    2py-pyma2-imo-zdab              13671    bim-edian2-ocho-bsdap13620    deam-3pazin-5pho-zdapee         13672    thpym-propa2s-eoco-bnsdap13621    mam2py-din-cpro-dfzdap          13673    bimhs-mepazin-ocho-bhsdab13622    imhs-edian2-eoco-bhsdap         13674    pyrhs-mepipen2-no1-psdab13623    2py-edian2-ocho-bhsdap          13675    impy-trias-oem-betadcph13624    2py-edian2-meo-psdab            13676    thpym-pyma2-fo-betainyl13625    emnim-mepipe-baeo-aspbzla       13677    me2py-pipmea-eoco-aspbzla13626    npip-trias-5pho-betadcph        13678    impy-pyma2-no1-bphabs13627    mam2py-din-emo-zdab             13679    2py-amn2-no2-betapy13628    phhs-25oxman2-ocho-bhsdap       13680    bhs-am3-sem-nzdap13629    me2py-dimen-cno-dfzdap          13681    bim-eta-eoco-zdab13630    npip-pyma2-ocho-bhsdab          13682    cl3pyme-diphmem-paco-glupha13631    me2py-pyma2-fo-csdap            13683    2py-diphmem-imo-bsdap13632    amim-pyma2-fo-psdab             13684    bz-dis-napo-mezphe13633    am2py-dimen-fo-bhsdap           13685    nim-pentadi-4amo-zdap13634    chhs-pymea-no2-glubzla          13686    morhs-m25thiz-no1-asppha13635    imhs-n2o2n-men-aspbzla          13687    am-m25thizman2-oem-bsdap13636    thpym-pazin-eoco-psdab          13688    ppy-pnymea-mommo-mezphe13637    deam-diphmep-mmen-bhsdap        13689    moegua-trias-5amo-bhsdab13638    amim-eta2s-mes-bphabs           13690    bhs-pazin-no2-psdap13639    impy-trias-chexo-osdap          13691    phpip-m25thiz-eoco-psdap13640    pippy-edian2-no1-bnsdap         13692    bim-25oxman2-napo-csdap13641    thpym-mepipe-no1-bsdap          13693    dhim-24thiman-napo-bsdap13642    amim-hexadi-oem-betapy          13694    piraz-pyma2-meo-betadcph13643    dmbim-24thiman-chexo-aspbzla    13695    bim-hexadi-fo-asppha13644    imhs-am3diaz-5pho-bhsdab        13696    pippy-amo2-imo-aspibua13645    imhs-edian2-meo-bphabs          13697    phhs-edia2-sem-nbeta34-13646    morhs-diphmep-imo-mezphe                 dimeoph13647    dhim-n2nme2n-chexo-aspibua      13698    2py-3pazin-meo-mezphe13648    cl3pyme-eta-baeo-betapy         13699    bimhs-edian2-5amo-psdab13649    dmam-tetradi-fo-bnsdap          13700    thpym-amn2-men-asppha13650    bimhs-pipmes-5amo-zlys          13701    prhs-dimephmep-emo-bhsdap13651    me2py-tetradi-meo-tsdap         13702    me2py-n2nme2n-baeo-mezphe13652    mam2py-24oxman2-oem-glupha      13703    imhs-tridi-fo-betapy13653    bimhs-thizn-imo-glyzdap         13704    thpym-edian2-no2-zdab13654    pippy-dis-hso-bnsdap            13705    me2py-eta-eoco-glupha13655    2py-amn2-ocho-psdap             13706    bhs-tridi-meteto-zdap13656    pyraz-dis-fo-bnsdap             13707    bim-eta-no1-betainyl13657    nmor-amn2-fo-bhsdab             13708    bim-edian2-meo-psdap13658    bim-tridi-no1-asppha            13709    impy-edia2-sem-nbeta34-13659    piraz-thizo-fo-csdap                     dimeoph13660    prhs-amo2-hso-glyzdap           13710    prhs-trias-5pho-bhsdap13661    bim-dimen-napo-psdab            13711    imhs-edian2-no1-bnsdap13662    thpym-amn2-no2-betapy           13712    bhs-eta-4amo-zdab13663    mam2py-m25thiz-mmen-zdapee      13713    piraz-m24thizman2-cnmo-13664    piraz-amo2-ocho-bhsdab                   betadcph13665    bimhs-dimephmep-imo-zdabs       13714    pippy-mepipe2-oem-nbetab13666    am2py-ms-5amo-bphabs                     naphth13667    gua-din-5amo-betadcph           13715    impy-din-napo-bsdap13716    bhs-trias-napo-betapy        13767    dhim-mepipen2-pyo-betapy13717    bim-thizo-men-betadcph       13768    hythpym-2pazin-mes-csdap13718    nmor-amn2-chexo-psdab        13769    tolhs-dimephmep-chexo-betapy13719    npip-3pazin-men-mezphe       13770    impy-am2-sem-nbetabnaphth13720    bhs-diphmem-mommo-zdabs      13771    pippy-dimephmem-5pho-aspbzla13721    bimhs-ams2-chexo-betainyl    13772    thpym-mea-oem-bsdap13722    dhim-mepipe2-oem-nbetapy     13773    amim-amo2-ocho-betadcph13723    gua-trias-mes-mezphe         13774    prhs-am2-sem-nzdab13724    ppy-eta-ocho-ibsdap          13775    imhs-tetradi-emo-osdap13725    pippy-propn-meo-betadcph     13776    prhs-24thizman2-mmen-13726    prhs-edian2-ocho-dfzdap               betainyl13727    bim-thizo-eoco-bphabs        13777    2py-eta-5pho-zdab13728    am2py-pipmea-oem-psdab       13778    bimhs-pipa-oeto-aspbzla13729    imhs-edian2-eoco-zdab        13779    hythpym-pipmea-meteto-aspaba13730    amim-dipch-eoco-dfzdap       13780    dhim-mepipe-5amo-bsdap13731    thpym-mepipe-peo-bsdap       13781    pyraz-eta-fo-aspibua13732    imhs-edian2-oem-zdab         13782    dmam-m25oxman2-meto-betainyl13733    2py-diphmep-pro-asppha       13783    thpym-props-fo-bsdap13734    bzl-amn3-emo-betainyl        13784    impy-din-men-bhsdap13735    pippy-dio-emo-psdap          13785    mepip-diphmem-ocho-zdabs13736    mam2py-thizn-oem-asppha      13786    2py-edian2-mes-ibsdap13737    thpym-25thizman2-meteto-     13787    piraz-pipmea-men-zdabs
     dfzdap                       13788    me-m25thiz-imo-betadcph13738    am2py-2pazin-5amo-csdap      13789    dmthpym-m24thizman2-mes-13739    imhs-24thiman2-5amo-glyzdap           bnsdap13740    bimhs-tetradi-5amo-bphabs    13790    mam2py-dio-oem-psdab13741    hythpym-diphmep-fo-aspaba    13791    2pmhs-n24thima-no2-zdap13742    chhs-hexas-5amo-mezphe       13792    thpym-eta-eoco-psdab13743    imhs-pazin-meo-zdab          13793    am-dimephmem-chexo-zdap13744    amim-amn2-mes-betadcph       13794    hythpym-edian2-ocho-mezphe13745    ibhs-tridi-meteto-bhsdab     13795    me2py-24oxman2-5pho-bnsdap13746    thpym-m25thiz-ocho-betadcph  13796    2py-pazin-mes-betapy13747    am4py-m25thiz-emo-aspaba     13797    bimhs-ams3-napo-zlys13748    npip-pipmeo-men-bhsdab       13798    me2py-edia2-sem-nbetameph13749    bhs-edian2-imo-csdap         13799    amim-pazi2n-men-osdap13750    imhs-mepipe-o2-bsdap         13800    nmor-25thizman2-men-bhsdap13751    thpym-n2nme2n-oem-glyzdap    13801    tolhs-m24thizman2-pro-bsdap13752    imhs-dipch-cno-ibsdap        13802    menim-dis-imo-mezphe13753    thpym-amo2-oem-zdap          13803    phhs-25oxman2-napo-zdap13754    prhs-pymea-napo-betainyl     13804    2py-diphmep-daco-mezphe13755    ibhs-trias-napo-csdap        13805    bhs-dio-oem-betadcph13756    phpip-pymea-chexo-bnsdap     13806    amim-props-no1-aval13757    am2py-diphmep-5pho-betainyl  13807    nim-24thizman2-men-aspibua13758    piraz-m25thiz-no2-mezphe     13808    bzl-m25thizman2-ocho-13759    mam2py-hexas-fo-aspibua               betainyl13760    2py-eta-no2-bsdap            13809    2py-pyma2-napo-psdap13761    deam-mea-peo-aspaba          13810    4pmhs-pazin-fo-zlys13762    thpym-mepipe-oem-zdab        13811    am2py-amo2-men-dfzdap13763    bimhs-amn2-no1-oxal          13812    thpym-pipmes-no1-aspibua13764    imhs-ams2-cnmo-glyzdap       13813    bzl-am2-oem-nzdap13765    am2py-pyma2-ocho-zdap        13814    me-edian2-no2-zdabs13766    gua-m24oxman2-oem-aval       13815    piraz-dimephmem-no1-aspbzla13816    hythpym-pnymea-5pho-zdap       13867    chmhs-dimen-imo-betainyl13817    bz-24oxman2-eoco-glyzdap       13868    me2py-ams2-chexo-aspibua13818    am2py-mepipen2-no2-bphabs      13869    imhs-amn2-oem-betapy13819    dhim-mea2s-men-psdab           13870    piraz-m25thizman2-eoco-zdabs13820    dmbim-mepipe-napo-psdab        13871    impy-pnymea-napo-bhsdab13821    nmhs-dimephmep-emo-zdab        13872    hythpym-mepazin-fo-betaet13822    hythpym-diphmem-no1-asppha     13873    thpym-edian2-meo-bsdap13823    tolhs-din-men-asppha           13874    moegua-m24thizman2-fo-13824    bimhs-edia2-sem-nbetameph               aspibua13825    mepip-amo2-ocho-csdap          13875    hythpym-dis-men-bhsdab13826    imhs-mepipe-eoco-zdapee        13876    phhs-trias-chexo-aspibua13827    morhs-25oxman2-no2-csdap       13877    piraz-mepipe-meo-betapy13828    thpym-mepipe-eoco-betadcph     13878    me2py-pipa-mes-zlys13829    am2py-tetras-chexo-bnsdap      13879    hythpym-m25thiz-napo-dfzdap13830    phpip-pipmes-ocho-zdap         13880    am2py-pyma2-no1-bhsdab13831    am2py-25oxman2-ocho-psdap      13881    bhs-24oxman2-oem-zdab13832    mam2py-trias-napo-betapy       13882    mam2py-pipa-no2-zdabs13833    hythpym-dimephmem-meto-        13883    bim-mepipe-meo-zdab
     aspbzla                        13884    imhs-am3-sem-nbetapy13834    bimhs-thizn-mes-ibsdap         13885    dmam-din-4pho-betapy13835    am2py-thizs-5pho-thizzdap      13886    2py-am3-oem-nbetabnaphth13836    z-thizo-fo-psdap               13887    amthiaz-trias-cno-aspbzla13837    me2py-mepazin-napo-asppha      13888    bimhs-edian2-5pho-aspbzla13838    2py-ams2-meteto-oxal           13889    imhs-pazin-meo-psdab13839    pippy-amn3-emo-csdap           13890    piraz-mepazin-meo-zdap13840    bhs-mepipe-no2-aspbzla         13891    bim-pazin-eoco-aspbzla13841    n2py-din-no1-oxal              13892    thpym-dis-no2-psdab13842    thpym-mepazin-5amo-zdabs       13893    amim-m25thizman2-oem-zdabs13843    hythpym-tetradi-ocho-osdap     13894    bimhs-tridi-daco-bhsdab13844    am2py-mepipen2-emo-glubzla     13895    4pmhs-pnymea-oem-psdab13845    impy-din-eoco-betaet           13896    me2py-diphmep-peo-bphabs13846    amim-dis-mes-bhsdap            13897    imhs-amn2-mes-bsdap13847    amim-mepipen2-oeto-dfzdap      13898    amim-pnymea-imo-betainyl13848    mam2py-diphmep-imo-zdap        13899    deam-diaz-mmen-glyzdap13849    piraz-amn3-5amo-bhsdab         13900    imhs-propn-meo-zdabs13850    bhs-m25thizman2-oem-bphabs     13901    impy-dis-oem-bsdap13851    bim-m24thizman2-meo-zdab       13902    imhs-edian2-no2-bnsdap13852    z-dimephmem-5amo-bphabs        13903    2py-thizn-napo-aspibua13853    pippy-dich-chexo-bnsdap        13904    emnim-m24thiz-eoco-bsdap13854    pippy-diphmep-5amo-bsdap       13905    dhim-3diaz-aco-aspibua13855    bhs-hexadi-5pho-aspibua        13906    bhs-eta-oem-bnsdap13856    hythpym-am3-oem-nzdab          13907    bhs-pazin-no2-psdap13857    bhs-24oxman2-fo-zdabs          13908    amim-eta-meo-betadcph13858    bim-propa2s-oem-betaet         13909    piraz-mepipe-meo-psdab13859    ec-24thizman2-4amo-betadcph    13910    bimhs-eta-hso-aspibua13860    ppy-pnymea-no2-psdab           13911    piraz-am3-sem-nbetameph13861    thpym-dis-5amo-zdab            13912    emnim-amo2-no1-bphabs13862    thpym-eta-meo-bsdap            13913    deam-pyma2-chexo-zdabs13863    bhs-amn3-nmo-glyzdap           13914    imhs-amn2-meo-psdap13864    piraz-dio-mmen-aspibua         13915    mam2py-dimen-emo-bsdap13865    amthiaz-tetras-emo-glyzdap     13916    am2py-din-fo-psdap13866    amthiaz-dis-pheo-mezphe        13917    am4py-diphmem-meo-aspaba13918    imhs-edian2-oem-bnsdap          13969    amim-trias-mmen-psdap13919    bim-dimephmep-napo-aval         13970    bim-dis-meo-betainyl13920    tolhs-ams2-emo-aspibua          13971    im-mea-meo-betadcph13921    imhs-trias-men-betaet           13972    2py-mepipe-ocho-psdap13922    bim-pazin-daco-bsdap            13973    nmor-25thizman2-napo-aspibua13923    mam2py-m24thizman2-no1-zdabs    13974    mam2py-pyma2-mommo-aspibua13924    dmam-ams3-no1-dfzdap            13975    am2py-24thiz-imo-zdab13925    tolhs-trias-chexo-betainyl      13976    bhs-din-oem-betainyl13926    phhs-thizo-cnmo-bnsdap          13977    bimhs-thizn-no1-aspaba13927    edothpym-m24thizman2-           13978    impy-24thizman2-5amo-bhsdab
     oeto-bphabs                     13979    bhs-pazin-no2-bhsdap13928    imhs-pnymea-fo-glyzdap          13980    2py-am2-sem-npsdap13929    amim-trias-imo-bnsdap           13981    phpip-dio-mes-csdap13930    moegua-am3-oem-nbetapy          13982    dhim-m25thiz-cpeo-zdap13931    imhs-pymea-men-bsdap            13983    2py-ams2-napo-bphabs13932    piraz-eta-meteto-bphabs         13984    amim-mepazin-no1-zlys13933    bim-eta-ocho-psdap              13985    am-dio-emo-betapy13934    emnim-amo2-daco-zdabs           13986    bim-indan2-meo-asppha13935    me2py-diphmem-ocho-aspbzla      13987    2py-dis-no2-osdap13936    hythpym-butn-napo-glyzdap       13988    amim-mepipen2-no2-zdab13937    bim-pipmea-meo-osdap            13989    am2py-amn2-napo-betadcph13938    pyrhs-dis-men-betapy            13990    imhs-edian2-meo-bhsdap13939    am2py-dimen-imo-csdap           13991    prhs-mepazin-oem-betaet13940    bim-edian2-no1-psdap            13992    bimhs-edia2-oem-nzdap13941    2py-amn2-no2-psdap              13993    mam2py-edia2-oem-nbeta34-13942    gua-trias-ocho-bnsdap                    dimeoph13943    gua-25oxman2-4amo-bhsdab        13994    dmam-pentadi-cpro-aspibua13944    me2py-dimephmep-emo-glyzdap     13995    bhs-amn2-eoco-zdab13945    bimhs-amn3-mommo-bnsdap         13996    bim-edian2-nol-glupha13946    phpip-m25thiz-4pho-betainyl     13997    pippy-pazin-ocho-ppsdap13947    piraz-mepipen2-fo-betadcph      13998    me-pipa-imo-betadcph13948    bhs-thizn-5pho-bnsdap           13999    mam2py-diphmem-no2-betaet13949    imhs-pymea-cpeo-bsdap           14000    chhs-thizn-oem-bhsdap13950    menim-dimephmep-eoco-aspbzla    14001    4pmhs-mepipen2-ocho-asppha13951    bim-eta-eoco-psdab              14002    pyrhs-mepazin-meo-betainyl13952    me2py-dimen-pheo-betainyl       14003    4pmhs-diphmep-4pho-psdap13953    mam2py-thizn-napo-zdabs         14004    moegua-dimen-nmo-mezphe13954    hythpym-eta2s-eoco-zdabs        14005    dpam-24thizman2-no2-glupha13955    bim-pazin-mes-psdap             14006    impy-m24thizman2-5pho-aspaba13956    bimhs-m25thiman2-imo-oxal       14007    cl3pyme-amn2-mes-betaet13957    bhs-mepazin-5amo-bnsdap         14008    bimhs-25oxman2-fo-psdab13958    am2py-tridi-5pho-asppha         14009    imhs-propn-emo-aspibua13959    bimhs-tetras-napo-zdab          14010    menim-edia2-sem-nbetameph13960    pyr-2pazin-eoco-zdabs           14011    impy-25oxman2-eoco-zdab13961    prhs-amn2-mommo-betadcph        14012    hythpym-edian2-nmo-dfzdap13962    thpym-amn2-eoco-zdab            14013    bimhs-edian2-cno-bsdap13963    amim-pnymea-meo-betainyl        14014    bhs-eta-oem-psdap13964    bim-24thizman2-mes-betainyl     14015    morhs-pnymea-nmo-bhsdab13965    bhs-mepipe-no2-bhsdap           14016    bhs-amn2-eoco-zdap13966    impy-25oxman2-5amo-glyzdap      14017    dhim-mea-men-bphabs13967    dhim-diphmem-5pho-ppsdap        14018    amthiaz-25thiman2-emo-betai-13968    2py-pa2in-5amo-aspbzla          nyl14019    phhs-mepazin-baeo-bphabs       14071    cl3pyme-props-no2-betapy14020    4pmhs-24thiz-emo-bhsdap        14072    bhs-mepipe-5pho-psdap14021    phpip-amn3-mes-aspbzla         14073    piraz-tridi-mes-glyzdap14022    fthpym-eta-eoco-dfzdap         14074    am2py-amn2-meo-aspbzla14023    bim-pipa-imo-bnsdap            14075    am2py-dimen-peo-aspibua14024    me2py-thizn-imo-oxal           14076    chmhs-eta-paco-psdap14025    amim-tridi-cnmo-psdapee        14077    dmam-24thiz-5amo-thizzdap14026    2py-pazin-eoco-bhsdap          14078    hythpym-propa2s-4amo-glyzdap14027    4pmhs-pnymea-no1-bhsdab        14079    2pmhs-ams3-no1-bsdap14028    thpym-mepazin-mommo-bsdap      14080    bhs-pipmeo-ocho-oxal14029    bim-n2nme2n-oem-asppha         14081    bim-din-eoco-betainyl14030    bim-pazin-no2-betapy           14082    2py-edian2-oem-bhsdap14031    piraz-amn2-napo-zdapee         14083    piraz-diphmep-eoco-dfzdap14032    am2py-pentadi-emo-aval         14084    bimhs-pipmea-4pho-psdap14033    gua-amn3-oem-dfzdap            14085    pippy-amn2-men-tsdap14034    tolhs-m25thiz-emo-asppha       14086    bhs-24thiz-no2-mezphe14035    chhs-mepazin-napo-mezphe       14087    thpym-amn2-meo-psdap14036    pyrhs-24thiman2-pyo-zorn       14088    mam2py-dimephmep-daco-14037    piraz-mepipen2-cpro-psdab               glyzdap14038    dmthpym-pipmes-mommo-bnsdap    14089    bimhs-dimephmep-pro-bsdap14039    thpym-edian2-5pho-psdab        14090    nmor-edian2-men-csdap14040    amim-dimephmep-ocho-zdap       14091    bhs-amn2-meo-zdab14041    bimhs-m25thiz-5pho-betadcph    14092    morhs-mepipe-napo-zdap14042    amim-trias-pro-zdabs           14093    2py-pnymea-chexo-zdabs14043    piraz-amn2-mes-dfzdap          14094    dhim-diphmem-ocho-asppha14044    bhs-mepipe-no2-zorn            14095    npip-n2o2n-ocho-bphabs14045    bim-pazin-no2-zdab             14096    impy-mepipe-emo-bsdap14046    impy-thizn-peo-ppsdap          14097    impy-eta-no2-bphabs14047    amim-pazin-chexo-betadcph      14098    cl3pyme-dis-pheo-bhsdab14048    cl3pyme-tetradi-fo-betainyl    14099    amthiaz-eta-paco-glyzdap14049    bim-dis-chexo-betainyl         14100    2py-edian2-no1-betapy14050    pyrhs-mepazin-cno-betaet       14101    imhs-ams2-no2-bnsdap14051    chhs-n24thiman-no2-csdap       14102    impy-pipa-fo-aspibua14052    z-diphmep-5amo-aspbzla         14103    mam2py-pnymea-meo-asppha14053    bim-amn2-5pho-zdap             14104    dpam-25oxman2-chexo-betainyl14054    mam2py-dis-5pho-betadcph       14105    prhs-edian2-men-glupha14055    bhs-indan2-no1-bphabs          14106    am-din-imo-asppha14056    fthpym-pipmea-napo-csdap       14107    mam2py-pipmea-paco-asppha14057    imhs-amn2-mommo-zdabs          14108    morhs-mepazin-ocho-mezphe14058    pippy-din-pro-zdab             14109    piraz-thizs-men-bhsdap14059    ec-edian2-men-glupha           14110    imhs-m24thizman2-peo-bhsdap14060    piraz-pyma2-4amo-zdap          14111    hythpym-edian2-fo-betainyl14061    thpym-trias-mecpo-zdab         14112    pippy-m24oxman2-no1-zdap14062    pyraz-mepipe-ocho-tsdap        14113    tolhs-3pazin-aco-zdabs14063    bim-pazin-mes-zdap             14114    mam2py-mepipen2-ocho-dfzdap14064    impy-dio-ocho-zorn             14115    thpym-m25thiman2-no1-aspibua14065    thpym-pazin-no2-psdab          14116    mepip-25thizman2-oem-aspbzla14066    imhs-edia2-oem-nzdap           14117    dmthpym-amo2-hso-betapy14067    prhs-24thiz-5pho-glyzdap       14118    me2py-am3diaz-men-zdabs14068    impy-trias-4pho-dfzdap         14119    impy-thizn-fo-thizzdap14069    z-diphmem-no1-mezphe           14120    menim-eta2s-5amo-glupha14070    pyrhs-amn3-5amo-betadcph       14121    bim-pazin-imo-betapy14122    2py-2pazin-meo-betadcph         14173    bimhs-pipa-emo-glubzla14123    amim-amo2-5amo-zlys             14174    chmhs-dimephmep-men-dfzdap14124    dmbim-m24thizman2-peo-csdap     14175    impy-thizo-pyo-aspbzla14125    z-pnymea-no1-zdap               14176    dhim-mepazin-chexo-oxal14126    dhim-amn3-meo-aspibua           14177    bimhs-m24thizman2-no2-14127    mam2py-24thizman2-emo-dfzdap             betainyl14128    2py-n2nme2n-mes-zdap            14178    amim-dis-mes-zdap14129    nmhs-24thiz-no2-zdap            14179    imhs-pipa-5amo-bnsdap14130    me2py-pentas-mes-aspibua        14180    emnim-diphmep-napo-zdab14131    pyr-ams2-eoco-psdap             14181    thpym-edian2-no2-bhsdab14132    hythpym-25thiman2-chexo-aval    14182    mam2py-amo2-meo-bsdap14133    mam2py-mepipe-4pho-psdap        14183    imhs-edian2-mes-zdap14134    bhs-eta-no1-dfzdap              14184    thpym-24thizman2-fo-betapy14135    mam2py-props-daco-zdab          14185    pippy-mepazin-no1-bnsdap14136    dhim-dis-men-psdab              14186    am-3diaz-emo-betapy14137    bim-eta-fo-aspbzla              14187    piraz-mepazin-fo-bnsdap14138    dmam-pyma2-fo-betapy            14188    mam2py-thizn-no1-zdabs14139    piraz-m24thizman2-men-          14189    pyr-thizo-emo-bhsdap
     aspbzla                         14190    2py-pazin-no1-psdab14140    am2py-dimen-men-bphabs          14191    moegua-mepazin-meo-ppsdap14141    2py-eta-oem-bhsdap              14192    mepip-tridi-peo-mezphe14142    phhs-am3-sem-nbetabnaphth       14193    bhs-eta-mes-psdap14143    thpym-edian2-ocho-zdap          14194    chmhs-pazin-mes-aspaba14144    piraz-trias-men-zdabs           14195    pyraz-mepipen2-fo-zdabs14145    amim-diphmem-eoco-psdapee       14196    imhs-edian2-ocho-bnsdap14146    2py-pymea-nmo-betapy            14197    pyrhs-mepipe2-sem-nbetameph14147    me2py-dimen-cpro-betapy         14198    edothpym-dimephmep-no2-14148    bhs-amn2-meo-bsdap                       dfzdap14149    am-n2o2n-pro-aspaba             14199    deam-amo2-no2-csdap14150    dhim-diphmep-hso-aspbzla        14200    mam2py-m25thiz-5pho-bhsdab14151    menim-dimephmem-peo-bsdap       14201    bim-trias-fo-mezphe14152    thpym-25thizman2-mes-glyzdap    14202    chhs-diaz-mes-psdap14153    thpym-3diaz-5amo-betadcph       14203    deam-dimen-men-psdab14154    bimhs-ams2-meo-zdapee           14204    imhs-edian2-meo-bnsdap14155    cl3pyme-pnymea-baeo-zdab        14205    bimhs-tridi-hso-bhsdap14156    2pmhs-dipch-mecpo-mezphe        14206    hythpym-propn-eoco-aspbzla14157    imhs-amn2-4amo-osdap            14207    tolhs-am2-oem-nbetabnaphth14158    bz-25thiman2-pyo-asppha         14208    amim-m24thizman2-no2-14159    bim-mepipe-ocho-psdap                    betainyl14160    am2py-amn3-cpeo-aspbzla         14209    amthiaz-dis-oem-asppha14161    dmam-thizs-no1-zorn             14210    hythpym-pipa-4amo-bnsdap14162    prhs-diphmem-cno-bhsdab         14211    bhs-amn3-no1-betadcph14163    bhs-amn2-no2-zdab               14212    moegua-diphmep-emo-zdap14164    mam2py-amn3-5pho-betainyl       14213    thpym-mepipe2-oem-nbetameph14165    n2py-diphmem-cnmo-psdap         14214    npip-edia2-oem-npsdap14166    bzl-mepipe2-oem-nbetabnaphth    14215    tolhs-pyma2-5pho-zdap14167    mam2py-pazi2n-fo-zdab           14216    impy-ms-mes-aspbzla14168    bzl-25oxman2-no2-psdab          14217    piraz-tridi-oem-bphabs14169    n2py-ams2-mes-aspibua           14218    thpym-tetradi-napo-dfzdap14170    dmam-amn2-oeto-asppha           14219    bhs-trias-oeto-aval14171    amim-mepipe-mmen-tsdap          14220    bimhs-edian2-no1-zdab14172    am2py-pnymea-pro-dfzdap         14221    thpym-hexadi-ocho-zdabs14222    bim-amn2-5pho-zdab             14273    am2py-eta-meteto-zdabs14223    bimhs-mepipe-eoco-glubzla      14274    bim-edian2-oem-bsdap14224    nim-dis-emo-dfzdap             14275    amim-m24thizman2-baeo-14225    dmbim-24oxman2-emo-zdap                 aspbzla14226    pyr-pyma2-4amo-mezphe          14276    pippy-tridi-cnmo-bnsdap14227    2py-eta-mes-psdab              14277    npip-dimen-paco-glyzdap14228    morhs-amo2-eoco-zdap           14278    thpym-pnymea-emo-psdapee14229    bimhs-din-ocho-dfzdap          14279    n2py-dis-no2-asppha14230    bim-edian2-eoco-psdab          14280    bhs-25oxman2-emo-mezphe14231    edothpym-mepipen2-meo-bhsdap   14281    am2py-ams2-cpro-glyzdap14232    bhs-m25thizman2-aco-psdap      14282    dmam-diphmem-emo-csdap14233    imhs-ams3-baeo-csdap           14283    piraz-pymea-fo-zdap14234    piraz-amo2-men-csdap           14284    dhim-dimen-ocho-betaet14235    tolhs-mepipen2-men-psdab       14285    dhim-amn2-chexo-zdap14236    impy-m24thizman2-meo-          14286    pippy-25thiman2-pyo-glyzdap
     betainyl                       14287    bhs-dimephmep-imo-tsdap14237    edothpym-edian2-hso-mezphe     14288    moegua-m25oxman2-baeo-dfzdap14238    am2py-n24thiman-5pho-bhsdap    14289    nmhs-dis-mes-zdabs14239    me2py-dimen-mes-bhsdab         14290    me2py-thizn-men-betainyl14240    dhim-24thiman-no1-aspbzla      14291    bhs-amn2-no2-bsdap14241    bhs-25oxman2-pheo-glupha       14292    ppy-tridi-no1-csdap14242    imhs-dimephmem-emo-betadcph    14293    bim-pipa-oem-psdap14243    piraz-24thiz-5pho-bnsdap       14294    im-dio-5amo-mezphe14244    2py-mepipe-emo-aspbzla         14295    amim-props-men-mezphe14245    piraz-24thiz-nmo-bhsdab        14296    am2py-din-no1-asppha14246    tolhs-tridi-no1-glyzdap        14297    dhim-pazin-no2-psdapee14247    chhs-amn3-men-betainyl         14298    fthpym-pipa-no2-betaet14248    chhs-n2o2n-eoco-bhsdap         14299    bhs-edian2-no1-psdap14249    bimhs-24thiz-imo-bphabs        14300    edothpym-pentadi-meo-14250    2py-dimephmep-ocho-psdap                betadcph14251    pyrhs-pipmeo-men-bhsdab        14301    cl3pyme-propn-meo-glyzdap14252    pippy-pazin-no1-betaet         14302    n2py-pipmea-no1-zdabs14253    piraz-amn2-imo-bphabs          14303    bhs-propa2s-chexo-betapy14254    prhs-hexadi-cpeo-betapy        14304    bim-amn2-meo-bsdap14255    pippy-dis-5amo-thizzdap        14305    hythpym-din-men-bhsdap14256    mam2py-mepipe2-sem-nzdab       14306    gua-thizn-oem-betapy14257    pyraz-dimephmep-fo-zdap        14307    pippy-pymea-no2-psdap14258    me-25thizman2-emo-asppha       14308    2py-din-5amo-zdap14259    dhim-dis-no2-aspbzla           14309    am2py-ams2-no1-psdab14260    bimhs-butn-chexo-zdap          14310    imhs-pymea-napo-bnsdap14261    me2py-dimephmep-no2-glyzdap    14311    impy-edian2-cpro-asppha14262    thpym-din-mommo-betadcph       14312    am2py-m25thiz-no2-dfzdap14263    bhs-dimen-men-csdap            14313    piraz-24thiz-mecpo-psdap14264    thpym-mepipe-5amo-bnsdap       14314    bim-diphmem-paco-bsdap14265    gua-eta2s-fo-aspibua           14315    piraz-edian2-no1-csdap14266    2py-pipmea-oem-zdabs           14316    pippy-diphmem-no2-psdab14267    amim-amn3-oeto-aspibua         14317    me-mepipe-men-zdab14268    mam2py-25oxman2-no2-glyzdap    14318    mam2py-amo2-mes-psdab14269    bimhs-thizs-aco-psdap          14319    imhs-trias-napo-aspibua14270    deam-props-ocho-zdab           14320    thpym-amn2-no2-psdap14271    impy-diphmep-eoco-bsdap        14321    nmhs-24thiz-daco-bnsdap14272    n2py-dimephmem-ocho-zdab       14322    impy-dimephmem-mommo-bsdap14323    imhs-amo2-no1-bphabs            14374    2py-amn2-mes-psdap14324    me-tridi-peo-asppha             14375    2pmhs-25thiz-eoco-csdap14325    dmam-mepipe-meteto-glyzdap      14376    me-edian2-emo-bsdap14326    nmor-am3diaz-no2-betapy         14377    thpym-din-pheo-bphabs14327    am2py-dimephmep-oem-mezphe      14378    bimhs-trias-meo-zdabs14328    thpym-din-mes-betapy            14379    dpam-amo2-fo-zdap14329    piraz-24thiz-nmo-psdab          14380    pippy-am3diaz-5pho-mezphe14330    bhs-thizs-emo-csdap             14381    bimhs-diphmep-mes-betapy14331    pippy-pnymea-baeo-csdap         14382    n2py-m25thiz-napo-mezphe14332    impy-pipmea-chexo-psdap         14383    hythpym-hexas-mes-asppha14333    amim-amn2-eoco-zdap             14384    pippy-amn2-nmo-zdap14334    thpym-mepipe-meo-psdap          14385    amim-diphmem-cnmo-csdap14335    pyraz-amn3-no1-psdab            14386    bhs-pipa-5amo-betainyl14336    bhs-mepipe-mes-zdab             14387    chmhs-dimen-4amo-thizzdap14337    impy-ms-meo-dfzdap              14388    dhim-amo2-5amo-bhsdab14338    4pmhs-diphmem-mmen-aspbzla      14389    dmthpym-amo2-chexo-bphabs14339    thpym-edia2-sem-nbeta34-        14390    phhs-props-oem-csdap
     dimeoph                         14391    bhs-pazin-eoco-betapy14340    bim-mepipe-meto-mezphe          14392    bim-pazin-mes-zdab14341    bim-eta-5pho-zdap               14393    bim-eta-no1-bhsdap14342    amim-mepipen2-meo-csdap         14394    hythpym-mepipen2-men-aspbzla14343    ec-dimephmem-men-zdapee         14395    imhs-dimen-imo-asppha14344    prhs-amo2-oem-bhsdap            14396    moagua-m25thiz-oem-psdab14345    deam-thizs-ocho-bsdap           14397    me2py-pyma2-pyo-csdap14346    piraz-pentas-fo-csdap           14398    bim-pnymea-pheo-osdap14347    me2py-ms-mmen-zdabs             14399    impy-m25thiz-imo-psdap14348    piraz-diphmep-no1-glubzla       14400    chhs-m25thiz-mecpo-bphabs14349    bhs-amn3-5pho-bhsdap            14401    am2py-pipmea-chexo-glyzdap14350    amim-mepipen2-no2-glyzdap       14402    bhs-dis-chexo-glyzdap14351    thpym-mepipe-meo-betapy         14403    am4py-dis-aco-betadcph14352    ibhs-tridi-mes-betainyl         14404    mam2py-eta-emo-betadcph14353    mepip-mepipen2-5pho-asppha      14405    am2py-indan2-hso-betainyl14354    mam2py-pipa-imo-betapy          14406    pippy-pymea-eoco-zdabs14355    2py-amn2-oem-zdap               14407    imhs-eta-eoco-bsdap14356    dhim-pazi2n-eoco-zdabs          14408    cl3pyme-thizs-napo-psdap14357    hythpym-amn3-fo-aspibua         14409    impy-pipa-fo-bhsdab14358    pippy-pymea-men-mezphe          14410    pippy-24thiman2-emo-dfzdap14359    gua-mepazin-mecpo-zdabs         14411    am2py-pazin-5amo-asppha14360    imhs-dimephmem-no2-aspbzla      14412    imhs-edia2-sem-nbetameph14361    hythpym-25oxman2-imo-aspbzla    14413    nmhs-m24thizman2-men-bsdap14362    impy-thizo-oem-bnsdap           14414    amim-mea-cno-betapy14363    me2py-trias-fo-asppha           14415    dmbim-am2-oem-nzdap14364    hythpym-mepipe-imo-bphabs       14416    mam2py-dimen-chexo-bsdap14365    dhim-diphmem-oem-bsdap          14417    thpym-edian2-ocho-betapy14366    impy-diphmep-daco-aspbzla       14418    impy-diphmem-nmo-dfzdap14367    2py-amn2-mes-bsdap              14419    moegua-thizs-chexo-zdab14368    imhs-mepipe2-oem-nzdap          14420    impy-m25thiz-chexo-zorn14369    morhs-25oxman2-napo-bsdap       14421    me2py-diphmep-no1-bhsdap14370    thpym-edian2-no2-bsdap          14422    am-tetradi-chexo-zdabs14371    piraz-mepipen2-fo-ppsdap        14423    impy-mepazin-men-asppha14372    imhs-pazin-no2-bhsdap           14424    bim-25thiz-oem-bphabs14373    bimhs-dio-fo-betadcph           14425    ec-dimephmem-imo-aspibua14426    bim-pentadi-5amo-glupha        14477    bhs-diphmem-5amo-glyzdap14427    dmam-pipmea-mes-mezphe         14478    dmthpym-amn2-no2-zdab14428    edothpym-dio-5pho-aspbzla      14479    pippy-25thiz-imo-bnsdap14429    pippy-pyma2-napo-psdap         14480    dhim-din-napo-betapy14430    am2py-din-pro-aspibua          14481    piraz-amn3-no2-csdap14431    piraz-tridi-ocho-bphabs        14482    prhs-edian2-men-thizzdap14432    ibhs-diaz-eoco-bnsdap          14483    amthiaz-eta-paco-dfzdap14433    dhim-pymea-emo-zdab            14484    ppy-25oxman2-5amo-aspibua14434    thpym-amn2-meo-bsdap           14485    bhs-pazin-5pho-zdap14435    impy-props-chexo-glubzla       14486    impy-m25thizman2-ocho-zdabs14436    pyr-diphmep-napo-mezphe        14487    impy-pnymea-fo-aval14437    phhs-m25thizman2-men-mezphe    14488    nmhs-pentas-oem-glyzdap14438    2py-pazin-meo-zdap             14489    4pmhs-mepipen2-chexo-aspibua14439    4pmhs-ms-mes-zdap              14490    thpym-25thiz-chexo-psdap14440    2py-amn2-ocho-zdab             14491    dmthpym-din-cno-psdap14441    thpym-mepipe-mes-bsdap         14492    bhs-pazin-5pho-betapy14442    dhim-pentadi-paco-zdab         14493    4pmhs-dimen-5amo-bhsdap14443    am2py-mepazin-paco-csdap       14494    me2py-tetradi-no2-mezphe14444    2py-eta-5pho-bhsdap            14495    chhs-dimephmep-5amo-aspbzla14445    me2py-24thiz-oem-aval          14496    z-am2-sem-nzdab14446    amim-diphmem-5amo-aspibua      14497    thpym-amn2-oem-bnsdap14447    pyr-pazin-men-psdap            14498    amim-m24oxman2-fo-zdab14448    me2py-m24thizman2-pheo-        14499    morhs-3pazin-oem-zdabs
     bhsdap                         14500    mam2py-24oxman2-daco-bhsdab14449    2py-n24thiman-mes-psdap        14501    menim-pipmea-fo-zdap14450    emnim-2pazin-no1-psdap         14502    impy-pnymea-fo-zlys14451    am2py-pentas-chexo-zorn        14503    bim-diphmem-imo-mezphe14452    imhs-din-meto-bhsdap           14504    2py-m25thiman2-chexo-psdab14453    impy-thizs-men-zdabs           14505    piraz-dis-oem-asppha14454    me2py-tetradi-5pho-mezphe      14506    moegua-dio-5amo-zdapee14455    prhs-props-aco-bphabs          14507    pippy-pyma2-mecpo-bphabs14456    bhs-edian2-mes-psdab           14508    am-24thiz-emo-csdap14457    mam2py-amn3-no2-glyzdap        14509    am2py-din-peo-csdap14458    cl3pyme-din-men-psdapee        14510    imhs-eta-mes-bnsdap14459    thpym-am3-oem-nbeta34dimeoph   14511    am-indan2-no1-bphabs14460    thpym-m24thizman2-5amo-bsdap   14512    mam2py-amo2-mecpo-betadcph14461    pippy-24thiman2-mecpo-psdab    14513    moegua-edian2-emo-betapy14462    bhs-thizn-nmo-betainyl         14514    2py-mepipe-mes-bnsdap14463    bimhs-diphmep-meo-glyzdap      14515    im-dimephmep-nmo-dfzdap14464    bhs-eta-ocho-zdap              14516    bimhs-24thizman2-napo-csdap14465    phpip-25thiz-chexo-psdab       14517    amim-diphmep-men-zdab14466    tolhs-amn3-napo-ppsdap         14518    bim-n24thiman-paco-asppha14467    bimhs-thizn-meo-glyzdap        14519    am2py-pazin-5pho-bnsdap14468    hythpym-mea2s-imo-zlys         14520    am2py-din-meo-csdap14469    pippy-pipmea-meo-betainyl      14521    moegua-pyma2-no1-mezphe14470    bim-amn2-mommo-psdap           14522    bhs-mepazin-mes-psdap14471    am2py-pipmea-5amo-glupha       14523    bim-ams2-chexo-betainyl14472    bim-mepipe-no1-bnsdap          14524    z-m24thizman2-fo-bsdap14473    amim-pentas-men-glupha         14525    am2py-pipmea-napo-zdabs14474    dhim-am3-oem-nbeta34dimeoph    14526    2py-24thiman2-emo-aspbzla14475    am4py-mepazin-no1-zdabs        14527    bim-am3-sem-nzdap14476    imhs-eta-ocho-zdab             14528    thpym-pazin-ocho-zdab14529    bhs-24thizman2-meo-zdab          14580    bim-amo3-meo-zdab14530    impy-mepipe-5amo-bnsdap          14581    2py-pnymea-5amo-bsdap14531    menim-din-chexo-bnsdap           14582    bim-mepazin-imo-zdab14532    me2py-diaz-oem-zdab              14583    imhs-amn2-no2-bnsdap14533    mam2py-propa2s-eoco-aspbzla      14584    bimhs-mepazin-no2-betadcph14534    mam2py-dimephmep-baeo-           14585    thpym-amn2-eoco-bsdap
     aspibua                          14586    amthiaz-m25thiz-nmo-csdap14535    pippy-amo2-emo-bphabs            14587    impy-tetradi-mes-bphabs14536    impy-24thiman2-ocho-aspaba       14588    dhim-am3-sem-nbetameph14537    thpym-mepazin-emo-zdapee         14589    bim-mepipe-mes-psdap14538    2py-trias-paco-bhsdap            14590    thpym-eta-5amo-betainyl14539    bim-pyma2-meo-betapy             14591    2py-amn2-meo-zdab14540    am2py-amn3-fo-bhsdap             14592    menim-diphmep-no2-zdab14541    bim-hexas-oem-zdap               14593    thpym-dis-oem-betainyl14542    phpip-trias-no1-betainyl         14594    imhs-m24thiman2-fo-asppha14543    edothpym-amn3-men-zdapee         14595    phpip-25thizman2-no2-bsdap14544    me2py-tetradi-cpro-aval          14596    thpym-dimen-no1-bnsdap14545    piraz-tridi-eoco-betapy          14597    cl3pyme-amn3-men-bphabs14546    bim-tetradi-paco-psdab           14598    bimhs-tridi-ocho-betapy14547    mepip-24thizman2-mmen-bhsdap     14599    hythpym-thizo-napo-psdab14548    phpip-dimephmem-cpeo-osdap       14600    hythpym-mepazin-aco-oxal14549    dhim-dimen-fo-asppha             14601    chhs-mepazin-napo-zdap14550    hythpym-diphmem-fo-aspibua       14602    2py-amn2-eoco-zdab14551    mam2py-trias-pyo-glupha          14603    impy-dis-napo-aspbzla14552    dmam-pyma2-5amo-bhsdab           14604    bim-m25thiz-napo-betainyl14553    impy-mea2s-no2-bnsdap            14605    npip-25oxman2-imo-zdap14554    hythpym-dis-mes-csdap            14606    2py-amn2-mes-zdap14555    ibhs-pazin-no2-zdab              14607    bhs-mea-no2-psdab14556    am2py-trias-emo-betainyl         14608    dhim-amn3-pyo-zdap14557    am2py-trias-no2-bsdap            14609    4pmhs-dimen-peo-bphabs14558    amim-tetradi-oeto-betapy         14610    amim-pyma2-ocho-osdap14559    am2py-25oxman2-men-mezphe        14611    ec-tridi-ocho-bphabs14560    impy-pazi2n-5pho-bnsdap          14612    4pmhs-mepipen2-eoco-csdap14561    hythpym-ams2-no1-bsdap           14613    thpym-din-mommo-zdab14562    pyr-tetradi-4amo-csdap           14614    bz-24thiz-oem-aspbzla14563    bhs-pazin-ocho-psdap             14615    bhs-tetras-men-betadcph14564    mam2py-din-chexo-glyzdap         14616    bim-pipmea-imo-aspibua14565    mepip-amn2-no2-zdabs             14617    bim-amn2-mes-bnsdap14566    fthpym-dimen-pheo-dfzdap         14618    impy-amn2-meo-bphabs14567    mam2py-edian2-eoco-asppha        14619    im-24thiz-mes-zdab14568    bhs-25oxman2-ocho-glyzdap        14620    2py-eta-eoco-bnsdap14569    4pmhs-3diaz-5amo-csdap           14621    mam2py-tridi-chexo-mezphe14570    bim-pazin-mes-bhsdap             14622    imhs-mepipe-no1-zdab14571    phhs-din-no1-betadcph            14623    piraz-pyma2-fo-csdap14572    impy-24thizman2-oem-bhsdab       14624    bim-tridi-no1-zdabs14573    npip-edian2-ocho-zdap            14625    2py-edian2-no1-zdap14574    thpym-pazin-5pho-psdab           14626    impy-25thizman2-pro-dfzdap14575    pippy-tetradi-imo-glupha         14627    dmam-thizn-ocho-betainyl14576    imhs-pnymea-no1-glyzdap          14628    bhs-dimephmem-chexo-asppha14577    impy-pymea-5pho-psdab            14629    impy-thizo-oeto-dfzdap14578    pippy-trias-no2-betapy           14630    mam2py-thizo-no2-glyzdap14579    phhs-edian2-oem-aspbzla          14631    bim-diphmem-mommo-bsdap14632    dhim-dis-eoco-aspbzla           14683    imhs-dich-ocho-bphabs14633    impy-pyma2-5amo-dfzdap          14684    imhs-dimen-5pho-aspibua14634    imhs-24thizman2-fo-bhsdap       14685    bim-edian2-ocho-betapy14635    piraz-3diaz-no2-aspbzla         14686    thpym-amn2-oem-zdapee14636    imhs-mepipe-mes-zdab            14687    bhs-hexas-eoco-psdap14637    piraz-am2-sem-nzdab             14688    pippy-trias-chexo-aval14638    am2py-dimen-chexo-betainyl      14689    mam2py-pazi2n-ocho-aspbzla14639    dhim-mepipe-eoco-bhsdab         14690    bimhs-amn2-cno-betadcph14640    impy-dimephmep-no1-osdap        14691    dmbim-m24thizman2-eoco-14641    bim-m25thiz-fo-zdapee                    bnsdap14642    bhs-dis-emo-glyzdap             14692    imhs-amn2-mes-bnsdap14643    imhs-mepipe-no2-psdab           14693    2py-thizo-mommo-bhsdab14644    am4py-ams2-no2-aspibua          14694    bhs-pazin-no1-zdab14645    bim-pentadi-fo-bphabs           14695    am-m24thizman2-ocho-osdap14646    dhim-mepazin-men-bnsdap         14696    4pmhs-edian2-mmen-psdab14647    piraz-mepipe2-sem-nbetab        14697    dpam-thizs-5pho-aval
     naphth                          14698    thpym-pipa-nmo-asppha14648    mam2py-mepipe-no1-betainyl      14699    n2py-pentas-eoco-psdab14649    amthiaz-m24thiman2-mes-zdabs    14700    npip-mepipe-meo-mezphe14650    mam2py-dimephmep-cno-aval       14701    imhs-dimephmep-co-csdap14651    4pmhs-dimephmep-mecpo-bhsdab    14702    chmhs-pyma2-cno-bsdap14652    gua-m24thiz-fo-zdab             14703    cl3pyme-pnymea-eoco-bphabs14653    amim-amn2-ocho-glyzdap          14704    thpym-edian2-no2-bhsdap14654    bhs-pazin-meo-bsdap             14705    thpym-mepipe-no2-zdab14655    am4py-dimen-meteto-betainyl     14706    2py-amn2-ocho-bnsdap14656    bhs-edian2-ocho-bhsdap          14707    nim-pymea-emo-bnsdap14657    am2py-25oxman2-4pho-bhsdap      14708    mam2py-pymea-emo-aspbzla14658    bhs-25oman2-baeo-zlys           14709    tolhs-propn-no1-psdab14659    bimhs-thizn-men-bsdap           14710    phhs-tridi-eoco-glyzdap14660    pyrhs-dimen-5pho-zdap           14711    thpym-edian2-ocho-psdap14661    nmor-am3diaz-emo-psdab          14712    nim-pipa-chexo-glyzdap14662    am2py-diphmem-emo-zlys          14713    mam2py-mepipe-mommo-psdab14663    impy-pnymea-imo-oxal            14714    mam2py-edian2-emo-zdabs14664    dhim-amo2-5pho-csdap            14715    thpym-edian2-eoco-psdap14665    dmbim-pnymea-5pho-bhsdab        14716    fthpym-butn-peo-bphabs14666    imhs-ams2-chexo-csdap           14717    bimhs-edian2-5pho-aspbzla14667    dmthpym-ams2-fo-bhsdap          14718    ibhs-edian2-meo-mezphe14668    bzl-25oxman2-oem-zdap           14719    imhs-dimephmem-fo-glupha14669    impy-pymea-chexo-glupha         14720    dmbim-butn-chexo-bhsdab14670    bzl-amo2-mes-aspbzla            14721    amthiaz-m25thizman2-5amo-14671    ec-eta-cpeo-mezphe                       bhsdap14672    moegua-dimephmem-fo-zlys        14722    ec-din-mecpo-bhsdab14673    bimhs-diphmep-meo-dfzdap        14723    me-hexas-4pho-bphabs14674    ppy-24thiz-baeo-dfzdap          14724    2py-ams3-meo-psdapee14675    imhs-pymea-4amo-aspbzla         14725    dhim-tetradi-5pho-betadcph14676    thpym-tetradi-meo-psdab         14726    impy-eta-5amo-bsdap14677    deam-pnymea-cnmo-zdab           14727    thpym-edian2-mes-zdap14678    dmbim-amo2-men-bsdap            14728    bhs-mepipen2-no2-aspbzla14679    2py-m25thiz-mes-aspbzla         14729    2py-eta-eoco-psdap14680    am2py-din-ocho-psdap            14730    am2py-amo2-napo-bhsdab14681    pippy-thizn-napo-betapy         14731    thpym-m25thiman2-chexo-bsdap14682    pippy-diphmem-eoco-glubzla      14732    bim-mepazin-ocho-bhsdab14733    amim-pipa-no2-osdap             14784    bim-eta-oem-psdab14734    me2py-dipch-hso-bhsdap          14785    amim-m25thiz-5pho-aspbzla14735    fthpym-amn2-no2-bhsdap          14786    2py-edian2-no2-psdab14736    amim-tetras-5amo-dfzdap         14787    bhs-dimephmem-napo-bhsdab14737    bz-amo3-meo-mezphe              14788    nmhs-25thiman2-5pho-bnsdap14738    bimhs-dis-meo-bhsdap            14789    2py-amn2-meo-bnsdap14739    4pmhs-dimephmep-chexo-betapy    14790    imhs-amn2-no2-psdab14740    thpym-tetradi-cno-aspbzla       14791    thpym-mepipe-eoco-bhsdap14741    thpym-edia2-oem-nzdab           14792    dhim-mepazin-cno-bnsdap14742    bz-24thiz-mes-betapy            14793    z-diphmep-cpeo-glyzdap14743    me2py-edia2-oem-nbetameph       14794    amim-pazin-mes-bhsdap14744    emnim-pyma2-no2-oxal            14795    thpym-diphmem-baeo-zdab14745    me2py-thizs-4amo-aspbzla        14796    pippy-hexas-eoco-asppha14746    dhim-pipmes-eoco-zdap           14797    impy-m24thizman2-meteto-14747    me2py-am3-sem-nbetapy                    csdap14748    amim-24oxman2-no2-aspbzla       14798    am2py-m24thizman2-fo-csdap14749    am2py-am2-oem-nzdab             14799    mepip-dis-no1-aspbzla14750    bhs-pipa-no2-csdap              14800    moegua-pymea-imo-zdab14751    pippy-ams2-emo-aspbzla          14801    2py-mepipe-5pho-bhsdap14752    pippy-pymea-chexo-zdap          14802    dhim-tridi-mes-csdap14753    me-pyma2-cpeo-betainyl          14803    pippy-amn2-emo-csdap14754    mam2py-amo2-mes-mezphe          14804    2py-mepipe-no1-zdab14755    bimhs-mepipen2-meo-csdap        14805    am2py-25oxman2-aco-bphabs14756    bim-eta-meo-bsdap               14806    imhs-pazin-ocho-psdap14757    prhs-25oxman2-no1-bhsdab        14807    amim-24thizman2-fo-bnsdap14758    mam2py-25thiz-mmen-glyzdap      14808    dhim-dimephmep-fo-aspbzla14759    hythpym-dimephmep-oem-bsdap     14809    piraz-ams2-5pho-psdapee14760    2pmhs-pazin-meo-bhsdab          14810    dhim-dimephmem-imo-asppha14761    mam2py-24thiz-no1-betadcph      14811    pippy-dimephmem-oem-bphabs14762    thpym-eta-no2-zdab              14812    edothpym-mepipe-fo-zlys14763    2py-pipa-meteto-aspibua         14813    amim-mepazin-emo-oxal14764    imhs-diphmep-men-betapy         14814    2pmhs-ams2-chexo-aspibua14765    impy-pazin-cpro-bhsdab          14815    z-m24thizman2-napo-psdap14766    thpym-eta-no1-psdap             14816    bhs-amn2-chexo-psdab14767    dpam-amn3-pro-mezphe            14817    bimhs-24thiz-5amo-betainyl14768    am2py-eta-ocho-psdab            14818    menim-din-ocho-bhsdap14769    pippy-trias-meo-aspbzla         14819    bimhs-am2-sem-nbetapy14770    imhs-pipmea-oem-bsdap           14820    bimhs-24thiz-oem-mezphe14771    hythpym-pazin-pheo-oxal         14821    bim-eta-no2-betapy14772    dmthpym-m25oxman2-5pho-psdap    14822    pyraz-pentas-men-bnsdap14773    bhs-amn2-no1-betapy             14823    dhim-thizn-imo-dfzdap14774    imhs-tetradi-men-csdap          14824    amthiaz-pymea-mes-bphabs14775    bz-edian2-mes-zdab              14825    amim-tetradi-fo-aspbzla14776    pippy-pipmea-mecpo-zdabs        14826    imhs-am2-sem-nbetameph14777    n2py-dimephmep-fo-betapy        14827    thpym-2pazin-meteto-asppha14778    dmbim-25oxman2-5pho-betaet      14828    pippy-24thizman2-napo-bhsdap14779    4pmhs-thizn-meo-betaet          14829    pyrhs-ams2-5amo-zdapee14780    thpym-24thiz-no2-mezphe         14830    mam2py-am3-sem-nzdap14781    bhs-tridi-fo-zdap               14831    z-mepazin-napo-aspbzla14782    emnim-tetradi-chexo-aspibua     14832    amim-amo3-fo-ppsdap14783    thpym-24thizman2-meteto-        14833    2py-pazin-no1-psdap
     csdap                           14834    2py-dimen-5amo-psdap14835    mam2py-thizn-meo-bnsdap        14884    thpym-mepipe-meo-bnsdap14836    2py-mepipen2-eoco-aval         14885    bhs-amo2-men-psdab14837    dhim-mepipe-mes-asppha         14886    npip-eta-napo-betainyl14838    emnim-tridi-imo-mezphe         14887    thpym-tridi-napo-ibsdap14839    mepip-diphmep-mes-mezphe       14888    nmhs-trias-chexo-bhsdab14840    am2py-thizn-mes-glubzla        14889    phhs-24thizman2-napo-zdab14841    4pmhs-dio-mes-psdap            14890    me2py-dimen-chexo-bphabs14842    dhim-24thiz-meto-betainyl      14891    phpip-24thiz-mecpo-asppha14843    hythpym-pazin-4pho-betapy      14892    menim-edia2-sem-npsdap14844    thpym-m24thizman2-eoco-oxal    14893    dhim-amo2-men-aspibua14845    pyraz-dimephmep-oem-bphabs     14894    2py-mepipe-ocho-bsdap14846    me2py-dimen-no1-betainyl       14895    mam2py-pymea-meo-bhsdab14847    hythpym-m25thizman2-napo-      14896    thpym-eta-eoco-bsdap
     betainyl                       14897    mam2py-tridi-emo-bhsdap14848    mam2py-pymea-cno-mezphe        14898    bhs-amn2-no2-zdap14849    piraz-tridi-fo-csdap           14899    bimhs-pyma2-cpro-psdab14850    bim-pipmea-men-aspibua         14900    mam2py-dis-meteto-asppha14851    bim-amn2-mes-psdab             14901    prhs-mepazin-napo-psdap14852    bim-eta-meo-psdap              14902    nim-thizn-chexo-bphabs14853    hythpym-25thiman2-4pho-        14903    me-hexas-chexo-bsdap
     mezphe                         14904    thpym-dimephmep-nol-thizzdap14854    2py-eta-meo-psdab              14905    bhs-din-imo-dfzdap14855    am4py-thizo-no2-zorn           14906    piraz-amn2-eoco-betaet14856    thpym-mepipe-meo-betainyl      14907    bim-m24oxman2-cpro-zdap14857    amim-pipa-5pho-bsdap           14908    2py-eta-meo-bnsdap14858    bim-mepipe-5pho-zdab           14909    me2py-tridi-chexo-asppha14859    bim-pyma2-men-mezphe           14910    me2py-25thizman2-imo-zdabs14860    mepip-24thizman2-aco-dfzdap    14911    npip-m24thiman2-men-psdap14861    thpym-ams3-no1-dfzdap          14912    hythpym-amn3-peo-dfzdap14862    2pmhs-25oxman2-napo-bhsdab     14913    mepip-m24thizman2-napo-14863    hythpym-dimephmem-imo-zdab              asppha14864    piraz-24thizman2-meto-betapy   14914    imhs-ams2-ocho-csdap14865    pippy-diphmep-eoco-glyzdap     14915    gua-ams2-eoco-aspbzla14866    pyraz-tridi-mecpo-mezphe       14916    phpip-pipmea-cpeo-bphabs14867    amim-dis-5amo-thizzdap         14917    bimhs-diphmep-cpeo-bsdap14868    emnim-tetradi-pyo-bhsdab       14918    imhs-eta-oem-bhsdap14869    piraz-mepipe-fo-zdabs          14919    prhs-amn2-no2-bnsdap14870    amim-pipa-cno-csdap            14920    gua-24thiz-meo-tsdap14871    me2py-ams2-cno-betapy          14921    amthiaz-diphmep-5amo-aspbzla14872    ec-tetradi-5amo-zdap           14922    bhs-amn2-emo-zdap14873    gua-amo3-no1-bnsdap            14923    amim-trias-5pho-thizzdap14874    bimhs-mea-emo-glyzdap          14924    menim-mepazin-emo-betainyl14875    pippy-hexadi-imo-betainyl      14925    dmam-mepipe-men-csdap14876    mam2py-tetradi-eoco-dfzdap     14926    2py-eta-ocho-psdap14877    emnim-hexas-4pho-bhsdab        14927    pyr-butn-emo-zdapee14878    fthpym-din-4amo-bhsdap         14928    bim-thizn-meteto-bphabs14879    2pmhs-dimephmep-meteto-        14929    bimhs-dimephmep-pheo-bsdap
     aspbzla                        14930    bim-trias-men-bsdap14880    mam2py-pipmea-daco-betainyl    14931    am2py-edia2-oem-npsdap14881    me2py-amo2-ocho-glyzdap        14932    am2py-dimephmep-napo-14882    bim-amn2-mes-psdap                      betadcph14883    mam2py-amo2-napo-betadcph      14933    impy-thizn-oeto-betadcph14934    thpym-mepipe-no2-glupha         14985    dpam-mepazin-chexo-zdab14935    hythpym-24thizman2-fo-bhsdap    14986    mam2py-diphmep-meteto-14936    gua-n2o2n-emo-csdap                      aspbzla14937    2py-mepipe-meo-betapy           14987    piraz-thizn-no1-asppha14938    gua-pazin-men-aspbzla           14988    phpip-pipmeo-napo-bhsdap14939    impy-25oxman2-imo-betadcph      14989    2py-eta-no2-bnsdap14940    tolhs-diphmep-imo-bhsdab        14990    phhs-dimephmep-men-dfzdap14941    deam-edia2-oem-nbeta34-         14991    pippy-pyma2-chexo-psdapee
     dimeoph                         14992    2pmhs-thizn-5amo-glyzdap14942    imhs-dis-no2-zdap               14993    am2py-pazin-4pho-bsdap14943    imhs-pipmea-men-ppsdap          14994    hythpym-eta-eoco-osdap14944    dhim-dimen-5amo-betainyl        14995    edothpym-din-eoco-bnsdap14945    piraz-n2nme2n-ocho-zdab         14996    imhs-eta-5pho-psdab14946    deam-dimen-fo-bphabs            14997    2py-pnymea-pyo-betainyl14947    impy-amn2-pyo-glupha            14998    ec-dis-no1-bhsdap14948    chhs-mea2s-napo-zdap            14999    ppy-amo2-paco-bhsdap14949    bhs-indan2-5pho-zdabs           15000    deam-mepipe-emo-asppha14950    2py-dimephmem-meo-glyzdap       15001    2py-trias-mmen-psdab14951    bim-eta-oem-bhsdap              15002    dmam-m25thiz-chexo-zdap14952    morhs-dimephmep-pyo-bsdap       15003    impy-ams2-aco-psdap14953    bimhs-edia2-sem-nbetapy         15004    pyr-pymea-meo-psdab14954    npip-m25thiz-imo-glubzla        15005    bimhs-mepipen2-mes-zdab14955    2py-pazin-no2-psdap             15006    phhs-dimephmem-eoco-bphabs14956    moegua-pipmea-imo-zdabs         15007    pippy-m24thizman2-meo-bhsdab14957    nmhs-pipa-5amo-asppha           15008    pippy-n24thiman-mommo-mezphe14958    deam-pymea-eoco-betaet          15009    pippy-amn3-oem-psdap14959    bimhs-amo2-fo-bsdap             15010    piraz-amo3-pheo-zdap14960    impy-tridi-ocho-bsdap           15011    bim-diphmep-oem-psdab14961    thpym-edian2-5pho-psdap         15012    bzl-ms-emo-psdapee14962    thpym-mepipen2-5amo-psdab       15013    bim-pazin-no1-bsdap14963    bimhs-pyma2-aco-zdabs           15014    piraz-thizn-5amo-zdap14964    me2py-propn-no1-csdap           15015    bhs-pazin-5pho-betapy14965    imhs-pymea-eoco-dfzdap          15016    mam2py-dis-5amo-betadcph14966    nim-pazin-oem-mezphe            15017    imhs-m24thizman2-cnmo-14967    n2py-mepipe-pheo-zdap                    betainyl14968    2py-m25thiz-meo-bhsdap          15018    mam2py-pipmea-no2-aspbzla14969    me2py-pnymea-imo-tsdap          15019    phpip-pnymea-mes-csdap14970    bim-tetradi-5pho-bsdap          15020    am-thizn-no1-betainyl14971    thpym-pymea-chexo-psdab         15021    imhs-propa2s-mmen-bnsdap14972    imhs-amn3-eoco-mezphe           15022    gua-pipa-no2-aval14973    2py-mepipe2-sem-npsdap          15023    am4py-pnymea-mes-psdab14974    cl3pyme-pazi2n-fo-zorn          15024    imhs-am3-oem-nbetapy14975    imhs-dis-hso-glyzdap            15025    impy-ams2-oeto-zdab14976    phhs-mepazin-men-psdab          15026    imhs-din-meo-glubzla14977    bim-amn3-imo-dfzdap             15027    bzl-tetradi-daco-betapy14978    am-pazi2n-mommo-zdabs           15028    hythpym-n2o2n-fo-dfzdap14979    hythpym-dimen-no1-psdapee       15029    nmhs-m24thizman2-eoco-14980    impy-mepipe-cnmo-bphabs                  glyzdap14981    am2py-dimephmep-hso-glyzdap     15030    pippy-trias-emo-betainyl14982    imhs-mepipe-chexo-betainyl      15031    am4py-dimephmem-chexo-psdap14983    impy-propa2s-baeo-bhsdap        15032    thpym-pazin-mes-bsdap14984    hythpym-amo2-ocho-betapy        15033    bim-tridi-ocho-glubzla15034    bim-24thiz-men-zdap             15086    am4py-edian2-meo-bhsdap15035    2pmhs-amn3-imo-mezphe           15087    pippy-24oxman2-oem-mezphe15036    am2py-tetradi-oem-psdab         15088    phpip-24thiz-eoco-dfzdap15037    ec-dimephmep-pyo-dfzdap         15089    bim-pazin-meo-zdab15038    menim-edian2-meo-psdap          15090    morhs-pipa-5pho-zdab15039    bimhs-24thiman2-mommo-betapy    15091    am2py-tridi-nmo-aspbzla15040    z-eta2s-eoco-zdab               15092    ibhs-m24thizman2-fo-dfzdap15041    bhs-eta-oem-aspibua             15093    pyr-dis-chexo-asppha15042    2py-dimephmep-chexo-betapy      15094    thpym-pymea-no2-zlys15043    am2py-mepipen2-meo-ppsdap       15095    am2py-m25thiz-5amo-zdab15044    bhs-eta-oem-zdap                15096    piraz-thizn-emo-betapy15045    2py-mepipe-oem-psdab            15097    z-pyma2-cno-psdab15046    bimhs-amn2-oem-zlys             15098    am4py-m24thiz-mes-betainyl15047    pyr-pipa-daco-psdap             15099    bim-edian2-eoco-zdap15048    bim-diphmem-men-psdapee         15100    piraz-eta2s-hso-mezphe15049    impy-pnymea-men-psdab           15101    impy-eta-paco-glyzdap15050    bz-amo3-4amo-bphabs             15102    mam2py-dis-chexo-zdab15051    dmam-mepipen2-4amo-zdap         15103    pyraz-pyma2-eoco-psdab15052    bhs-eta-pyo-bhsdap              15104    dpam-edian2-men-bhsdap15053    2py-edian2-5pho-bhsdap          15105    bimhs-dipch-oem-asppha15054    dhim-m24thizman2-oeto-bhsdab    15106    am2py-3pazin-oeto-psdapee15055    2py-m25thiz-oeto-glyzdap        15107    bhs-edian2-mes-bsdap15056    bimhs-m25thizman2-meo-zlys      15108    bimhs-am3diaz-pyo-bphabs15057    bhs-m24thizman2-cpeo-aval       15109    me2py-am3diaz-mecpo-zdap15058    imhs-trias-chexo-dfzdap         15110    bim-pazin-5pho-psdap15059    phpip-amn2-meo-psdab            15111    dmam-mepipe-chexo-betadcph15060    gua-hexadi-mommo-betapy         15112    am4py-mea2s-napo-csdap15061    2py-amn2-meo-bsdap              15113    pippy-dipch-meto-bnsdap15062    2py-tetradi-cpeo-zdab           15114    am2py-trias-oem-dfzdap15063    mepip-butn-5pho-zdab            15115    hythpym-pentadi-no2-dfzdap15064    pippy-amn2-no1-zdabs            15116    prhs-amn2-chexo-asppha15065    bimhs-mea-ocho-mezphe           15117    prhs-dis-napo-psdab15066    dmbim-diphmem-oem-bphabs        15118    bimhs-din-pro-aspibua15067    thpym-mepipe2-oem-nbetapy       15119    nmor-pymea-peo-csdap15068    gua-tetradi-nmo-psdap           15120    dhim-amn3-5pho-zlys15069    pippy-dis-chexo-bhsdap          15121    me2py-dimephmem-imo-glyzdap15070    hythpym-pyma2-fo-zdab           15122    piraz-edian2-paco-dfzdap15071    piraz-amn3-fo-mezphe            15123    pippy-mepipen2-napo-zdabs15072    bhs-mepipen2-meteto-psdab       15124    bhs-amn3-peo-asppha15073    pyr-25oxman2-fo-thizzdap        15125    dmthpym-amo2-napo-psdab15074    am2py-25oxman2-baeo-zdap        15126    chhs-25oxman2-oem-betainyl15075    ibhs-am3diaz-no1-bhsdab         15127    menim-thizn-5amo-bphabs15076    dhim-pentas-meto-aspbzla        15128    npip-mepipen2-mes-zdabs15077    dhim-din-eoco-aspibua           15129    imhs-dimen-mes-thizzdap15078    bhs-pyma2-eoco-glyzdap          15130    2py-pyma2-men-aspibua15079    me-ams2-fo-betainyl             15131    amim-am2-sem-nbetapy15080    mam2py-amn2-ocho-bsdap          15132    am2py-m24thiz-eoco-aspbzla15081    bim-amn2-eoco-bhsdap            15133    dhim-mepipe-no2-bsdap15082    cl3pyme-am3-sem-nbetapy         15134    bz-mepipe2-sem-nbeta34-15083    piraz-pymea-imo-zdap                     dimeoph15084    bimhs-mepazin-5amo-bhsdap       15135    thpym-m24thizman2-eoco-zdab15085    bhs-dimephmep-emo-glyzdap       15136    dhim-eta2s-hso-asppha15137    emnim-din-chexo-zdabs         15155    dmthpym-n2o2n-mes-psdab15138    impy-pentadi-meo-betapy       15156    bim-amn2-no1-psdap15139    2py-mea-fo-mezphe             15157    thpym-indan2-no1-betapy15140    imhs-eta-no2-betapy           15158    mam2py-24thiz-hso-aspibua15141    pyrhs-eta-aco-psdap           15159    bimhs-pipmes-no2-mezphe15142    dhim-m24thizman2-napo-aval    15160    piraz-tridi-pheo-psdab15143    impy-pazin-mes-mezphe         15161    mam2py-amn2-5pho-zdab15144    imhs-pentadi-eoco-betainyl    15162    imhs-amn2-no1-psdab15145    thpym-n24thiman-imo-bnsdap    15163    dhim-pyma2-5amo-betainyl15146    dhim-dis-no2-glyzdap          15164    me2py-dipch-chexo-zdap15147    ec-pyma2-oem-aspbzla          15165    ec-thizn-cpeo-mezphe15148    npip-diphmem-men-aspibua      15166    mam2py-am2-oem-nbetapy15149    piraz-mepipen2-eoco-osdap     15167    tolhs-dimephmem-pro-bphabs15150    gua-pipa-fo-aspaba            15168    z-mepipen2-peo-zdab15151    im-amn3-no2-bnsdap            15169    pippy-edian2-5pho-bhsdap15152    bhs-ams2-meo-zdabs            15170    amim-edian2-5pho-mezphe15153    hythpym-edian2-men-bphabs15154    bim-pyma2-mes-bhsdap
在上表中使用了结构单元A、E、G和L的下列缩写
Figure A0080755402241
Figure A0080755402261
Figure A0080755402281
Figure A0080755402291
Figure A0080755402301
Figure A0080755402311
Figure A0080755402331
Figure A0080755402341
Figure A0080755402351
通常使用本领域技术人员已知的有机化学的方法,如标准著作例如Houben-Weyl,“有机化学方法”(Methoden der Organischen Chemie)、Thieme-Verlag、Stuttgart或March“高级有机化学”(Advanced OrganicChemistry)、第四版,Wiley & Sons所述,制备式I的化合物和制备它们所需的原材料。另外,进一步的制备方法还描述于R.Larock,“综合有机转化”(Comprehensive Organic Transformations),Weinheim 1989中,特别是制备烯烃、炔、卤化物、胺、醚、醇、酚、醛、酮、腈、羧酸、酯、酰胺和酰氯。为功能基团选择适宜的保护基团和此保护基团的引入或去除,描述于例如Greene和Wuts,“有机合成的保护基团”(Protective Groups in Organic Synthesis)第2版,Wiley & Sons,1991中。
可以在溶液或聚合物载体上进行式I化合物的合成,在每种情况下所用的反应条件是那些对于相应的反应已知并且适宜的反应条件。而且,还可以使用在此处未提及的但是是本身已知的方案。
I型化合物的一般合成,其中如上所述,A-E-可以是结构元素B-,而-U-T可以是结构元素-L,描述于方案1至7中。除非另有说明,所有原材料和试剂均可以购买或用常规方法从可以购买的前体制备。
例如,从作为中间体的通式II的相应取代的4-硫代-3,4-二氢嘧啶-2(1H)-酮开始,合成通式I的化合物。II型的4-硫代-3,4-二氢嘧啶-2(1H)-酮是已知的并且可以通过例如在Katritzky和Rees,“综合杂环化学”(Comprehensive Heterocyclic Chemistry),Pergamon出版,第3卷;第135-139页和在其中引用的文献中所述的已知方法制备。
合成4-硫代-3,4-二氢嘧啶-2(1H)-酮的优选方法包括,例如,将烯胺加成至异硫氰酸酯上并随后环化,如Goerdeler等,在化学通讯(Chem.Ber.)1963,第526-533页和Chem.Ber.1965,第1531-1542页中所述。4-硫代-3,4-二氢嘧啶-2(1H)-酮的制备特别优选根据Lamon在杂环化学杂志1968,5,837-844中所述的方法进行,此方法是基于烯胺与烷氧基-或芳氧基羰基异硫氰酸酯的反应。可以通过通式III的相应的烯胺衍生物(其中X优选为吗啉、吡咯烷或哌啶基)与伯胺反应,同时生成取代的4-硫代-3,4-二氢嘧啶-2(1H)-酮II(方案1),来完成式I化合物的合成。方案1如上所述,SG1是羧基官能团的保护基,或SG1-OOC-残基是T。
在固相上,例如通过使用羧酸官能团作为连接基,连接于一种固体载体上(SG1=固体载体),进行合成特别有效。例如由Bunin在“TheCombinatorial Index”(Academic Press,1998)中,详细描述了固相合成的方法。在U含有另一个官能团或氨基酸的侧链(该氨基酸含有一个所谓的侧链官能度)的情况下,则通过适宜的保护基团对它们加以保护是有益的。
为了进一步反应,用标准方法通过加入一种碱,将通式II化合物中的4-硫代基烷基化。作为碱可以使用一种碱金属或碱土金属氢化物如氢化钠、氰化钾或氢化钙,一种碳酸盐例如碱金属碳酸盐如碳酸钠或钾,一种碱金属或碱土金属氢氧化物如氢氧化钠或钾,一种醇化物例如甲醇钠、叔丁醇钾,一种金属有机化合物例如丁基锂或碱金属氨化物例如二异丙基氨基锂、双(三甲基甲硅烷基)氨基锂、钠或钾,叔胺例如三乙胺、1,8-二氮杂双环[5.4.0]十一碳-7-烯或乙基二异丙胺。特别优选使用碱金属碳酸盐例如Cs2CO3或叔胺例如乙基二异丙胺。
在通式I的化合物中的UE是氧或NRE 2的情况下,或在h=0,没有UE,并且因此A-E片段和G片段之间通过一个存在于片段中的N基团直接连接的情况下,优选将4-硫代基转化为相应的硫氰酸酯,这是通过使用溴化氰的烷基化完成的,例如如四面体通讯(Tetrahedron Letters)1991,32(22),2505-2508中所述(方案II)。然后可以将式IVa的硫氰酸酯与通式A-E-(UE)h-H(V)的适宜的胺或醇,用本领域技术人员已知的方法反应,需要的话加入一种碱,获得通式VI的化合物(方案II)。在此方案中,为了说明,-E’-代表没有(UE)h连接单元的空间结构单元E。
在通式I的化合物中的UE残基是硫的情况下,可以直接使用一种通式A-E-Y(VII)化合物作为烷化基剂,在通式A-E-Y(VII)中,基团Y是一种常规的离去基团例如卤素如氯、溴、碘或可以被卤素、烷基或卤烷基取代的芳基或烷基磺酰基,例如甲苯磺酰基、三氟甲烷磺酰基和甲基磺酰基或另一种等效的离去基团(方案II)。
UE=硫的通式I的化合物的另一种优选的制备方法,是将通式II的化合物转化为相应的硫基乙腈(IVb),然后它可以与结构式A-E-SH的硫醇(Vb)反应得到化合物VI。
在标准条件下,去除保护基团SG1(参见下文),产生通式I的化合物。在SG1是C1-C4烷基或苄基,或SG1-OOC-是T的情况下,通式VI的化合物直接对应于I型化合物。方案2
可以用作保护基团SG的是所有从事肽合成的技术人员已知的和惯用的保护基团,如其还描述于标准著作例如Bodanszky“肽合成实践(ThePractice of Peptide Synthesis)”,第二版,Springer-Verlag 1994和Bodanszky“肽合成原理”(Principles of Peptide Synthesis),Springer-Verlag 1984中。同样地,在本领域技术人员已知并例如由Greene和Wuts描述于“有机合成的保护基团”,第2版,Wiley & Sons,1991中的条件下,进行式VI化合物中保护基团和用于制备化合物V和VII所用的保护基团的去除。
优选使用的氨基保护基团是Boc、Fmoc、苄氧基羰基(Z)、乙酰基、三苯甲基或Mtr。所用的酸保护基团例如有SG1,优选C1-C4-烷基,例如甲基、乙基、叔丁基或苄基或三苯甲基,或以市售聚苯乙烯树脂的形式存在的结合聚合物的保护基团,例如2-氯三苯甲基氯树脂或Wang树脂(由Bachem或Novabiochem供应)。
对酸不稳定的保护基团(例如Boc、叔丁基、Mtr、三苯甲基)的除去,根据所使用的保护基团,可使用有机酸例如三氟乙酸(TFA)、三氯乙酸、高氯酸、三氟乙醇,磺酸例如苯-或对-甲苯磺酸,或无机酸例如盐酸、或硫酸来进行,通常过量使用酸。
在三苯甲基的情况下,加入硫醇例如茴香硫醚或苯硫酚是有益的。额外存在惰性溶剂是可能的但不总是需要。适宜并优选的惰性溶剂是有机溶剂例如羧酸如乙酸、醚如THF或二噁烷、酰胺如DMF或二甲基乙酰胺、卤代烃如二氯甲烷、醇如甲醇、异丙醇或水。上述溶剂的混合物也是适宜的。这些反应的温度在10℃至50℃,优选的范围为0℃至30℃。
通过用有机胺例如以5-50%CH2Cl2或DMF溶液形式存在的二甲胺、二乙胺、吗啉、哌啶处理,使对碱不稳定的保护基团发生裂解。这些反应的温度在10℃至50℃,优选的范围为0℃至30℃。
酸保护基团例如甲基或乙基的裂解优选通过在一种惰性溶剂中的碱性水解来进行。优选使用的碱为:碱金属或碱土金属氢氧化物,优选NaOH、KOH或LiOH。所使用的溶剂是所有常规的惰性溶剂,例如,烃如己烷、庚烷、石油醚、甲苯、苯或二甲苯,氯化烃如三氯乙烯、1,2-二氯乙烷、四氯甲烷、氯仿、二氯甲烷,醇如甲醇、乙醇、异丙醇、正丙醇、正丁醇或叔丁醇,醚如二乙醚、甲基叔丁基醚、二异丙醚、四氢呋喃、二噁烷,乙二醇醚如乙二醇单甲醚或单乙醚、乙二醇二甲醚,酮如丙酮、丁酮,酰胺如二甲基甲酰胺(DMF)、二甲基乙酰胺或乙酰胺,腈如乙腈,亚砜如二甲基亚砜、环丁砜、N-甲基吡咯烷酮、1,3-二甲基四氢-2(1H)-嘧啶酮(DMPU)、1,3-二甲基-2-咪唑烷酮,硝基化合物如硝基甲烷或硝基苯,水或上述溶剂的混合物。根据所使用的溶剂或溶剂的混合物,添加相转移催化剂可能是有益的。这些反应的温度通常在-10℃至100℃。
可以通过氢解去除的保护基团,例如苄氧基羰基(Z)或苄基,可例如通过在催化剂(例如一种在作为载体的活性碳上的贵金属)存在下的氢解而去除。适宜的溶剂如上文所描述,特别是醇如甲醇或乙醇,酰胺如DMF或二甲基乙酰胺,酯如乙酸乙酯。氢解通常在1至200巴的压力、0℃至100℃的温度下进行;添加酸如乙酸或盐酸可能是有益的。优选使用活性碳上的5-10%的Pd作为催化剂。
E型的结构单元通常用本领域技术人员已知的方法构建。所用的结构单元或是可购买的或可用文献中的已知方法获得的。某些这种结构单元的合成在实施例部分以示例的方式加以描述。
在V型和VII型化合物中存在的片段QE是杂芳基的情况下,所用的结构单元是购买的或用文献中的已知方法获得的。大量的制备方法详细地描述于Houben-Weyl的“有机化学方法”(E6卷:呋喃、噻吩、吡咯、吲哚、苯并噻吩、-呋喃、、-吡咯;E7卷:喹啉、吡啶;E8卷:异噁唑、噁唑、噻唑、吡唑、咪唑和它们的苯并稠合的代表,和噁二唑、噻二唑和三唑;;E9卷:哒嗪、嘧啶、三嗪、氮杂和它们的苯并稠合的代表,和嘌呤)。
通式化合物:HNRE 1-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4--(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-(UE)h-DE     (VIII)NC-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4--(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-(UE)h-DE          (IX)转化为通式化合物:A-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4--(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-(UE)h-DE         (X)A-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4--(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-(UE)h-DE         (XI)
可用本领域技术人员的已知方法,例如WO 97/08145中所述的方法完成。式VIII至XI中的基团DE代表H或NSG2基团。直接或在去除了相应的保护基团SG2之后,这些结构单元可以转化为通式I的化合物(方案II)。
方案3至7以示例的方式描述了大量引入A的方法,每种情况下所用的反应条件对于相应反应来说是已知的并适宜的反应条件。而且还可以使用本身已知的但未在此提及的案。
脲和硫脲(AE-1至AE-3)可以用有机化学的常规方法制备,例如通过将异氰酸酯或异硫氰酸酯与一种胺,需要的话在一种惰性溶剂中在加热下反应(Houben-Weyl,第VIII卷,157以下页)(方案3)。
方案3
Figure A0080755402411
方案4以示例的方式显示了AE-4型化合物的制备,如例如由Blakemore等在欧洲药物化学杂志,1987(22)2,91-100,或由Misra等在Bioorg.Med.Chem.Lett.1994 4(18),2165-2170中所述。
方案4
Figure A0080755402421
通式AE-5和AE-6的未取代的或环胍衍生物,可以用可购买的或可以简单地获得的试剂制备,如例如Synlett 1990,745,有机化学杂志,1992,57,2497,Bioorg.Med.Chem.1996,6,1185-1208;Bioorg.Med.Chem.1998,1185,或Synth.Comm.1998,28,741-746中所述。
通式AE-7的化合物,可以用与US 3,202,660相似方法制备,通式AE-9、AE-10、AE-11和AE-12的化合物,可以用与WO 97/08145的相似方法制备。通式AE-8化合物的制备显示于方案5中,例如可以使用Perkins等Tetrahedron Lett.1999,40,1103-1106中所述的方法制备。方案5总结了上述化合物的合成。
Figure A0080755402431
=稠合的环系如芳基或杂芳基
Figure A0080755402433
Figure A0080755402441
通式AE-13的化合物,可以用类似于Froeyen等,Phosphorus SulfurSilicon Relat.Elem.1991,63,283-293的方法制备。通式AE-14的化合物,可以用类似于Yoneda等,Heterocycles 1998,15N’-1,Spec.Issue,341-344的方法制备(方案6)。相应的化合物还可以用类似于WO 97/36859的方法制备:
方案6
Figure A0080755402442
通式AE-15的化合物的制备如Synthesis 1981,963-965,或Synth.Comm.1997,27(15),2701-2707所述。通式AE-16的化合物,可以用类似于有机化学杂志1991,56(6),2260-2262的方法制备(方案7)。
方案7
Figure A0080755402451
Figure A0080755402452
=稠合的环系如芳基、杂芳基、环烷基
Ex=-(CRx 3Rx 4)k1-(Ik)k2-(CRx 5Rx 6)k3-(Qx)k4-(CRx 7Rx 8)k5-(Tx)k6-(CRx 9Rx 10)k7-
本发明还涉及式IGL结构单元用于制备与整合素受体结合的化合物的用途
                    -G-L     IGL
本发明还涉及含有式IGL结构单元的药物。
本发明还涉及药物制剂,除了常规药物赋形剂外,它还包含至少一种式I的化合物。
可通过常用的方法经口服或胃肠外(皮下、静脉、肌内、腹膜内)应用本发明的化合物。也可通过鼻咽以蒸汽或喷雾的形式给药。还可以将本发明的化合物直接与相关组织接触给药。
根据患者的年龄、状况、体重和给药方式确定剂量。口服给药时活性成分每日的剂量通常在0.5至50mg/kg体重之间,胃肠外给药时在0.1至10mg/kg体重之间。
可用常规的固体或液体的药物形式应用此新的化合物,例如无包衣或薄膜包衣的片剂、胶囊、粉剂、颗粒剂、糖衣丸、栓剂、溶液、软膏、霜剂或喷雾剂等。这些药物形式可用常规的方法制备。为了制备这些药物形式,可将活性成分与常见的药物辅剂一起进行处理。这些药物辅剂例如为片剂粘合剂、填充剂、防腐剂、片剂崩解剂、流动调节剂、增塑剂、湿润剂、分散剂、乳化剂、溶剂、释放延缓剂、抗氧化剂和/或推进气体(参见H.Sucker等:Pharmazeutische Technologie,Thieme-Verlag,Stuttgart,1991)。如此获得给药形式的活性成分的含量通常为其重量的0.1至90%。
本发明还涉及式I化合物在治疗疾病的药物制备方面的应用。式I化合物可用于治疗人或动物的疾病。式I化合物与整合素受体结合。因此它们优选适于充当整合素受体配体,并适用于制备治疗与整合素受体相关的疾病的药物,特别适用于治疗这样的疾病,其中整合素与其天然受体之间相互作用失调,即出现增强或下降。
整合素受体配体指激动剂和拮抗剂。
相互作用的增强或下降指天然配体和/或整合素受体表达的增强或下降,因此也指天然配体和/或整合素受体数量的增加或下降,或天然配体对整合素受体亲和力的增强或下降。
与正常状态相比,存在整合素及其天然受体之间相互作用调节障碍的情况,也就是说当这种调节障碍不能与生理状态相一致时,出现相互作用的增强或下降。其相互作用的增强或下降可导致生理病理状态。
导致生理病理状态的调节障碍的水平依赖于单个机体和疾病的性质和位置。
可适用本发明式I化合物的整合素受体优选为α5β1、α4β1、αvβ5和αvβ3整合素受体。
特别优选的是式I化合物与αvβ3整合素受体结合,因此它们可特别优选地充当αvβ3整合素受体的配体,并且可用于治疗αvβ3-整合素受体和其天然配体之间相互作用增强或下降的疾病。
式I化合物特别优选地用于下面疾病的治疗:
诸如动脉粥样硬化、血管损伤或斯坦特固定模移植(Stentimplantation)后的再狭窄和血管成形术(新内膜形成、平滑肌细胞移位和增生)等的心血管疾病,
急性肾衰竭,
诸如糖尿病性血管病或视网膜病或者类风湿性关节炎的血管生成相关的微血管病,
血小板介导的血管闭塞、动脉血栓,
中风、心肌梗塞或中风后的再灌注损害,
诸如肿瘤转移或肿瘤生长(肿瘤引起的血管生成)的癌,
骨质疏松症(破骨细胞趋化和粘附至骨基质后的骨吸收),
高血压、牛皮癣、甲状旁腺机能亢进、佩吉特病、恶性高血钙、转移性溶骨损害、炎症、伤口愈合、心衰、充血性心衰(CHF),并可用于抗病毒、抗真菌、抗寄生虫或抗细菌的治疗和预防(吸附和内在化)。
为了在许多适应症中提高疗效,将式I化合物与至少一种其它化合物联合用药是有优势的。这些其它化合物的作用机制可与式I化合物相同或不同。
因此除了式I化合物和常规药物赋形剂外,此药物制剂还可包含至少一种其它的化合物,根据下面10组中的适应症来确定其选择。1组:
治疗血小板介导的血管闭塞或血栓的药物:
血小板粘附、活化或聚集抑制剂,诸如乙酰水杨酸、乙酰水杨酸赖氨酸、吡拉西坦(Pilacetym)、双嘧达莫、阿昔单抗(Abciximab)、血栓烷拮抗剂、诸如Tirofiban等的纤维蛋白原拮抗剂,或者诸如噻氯匹定或氯吡格雷(Clopidogrel)的ADP所致聚集的抑制剂,
降低凝血酶活性或阻止凝血酶形成的抗凝剂,诸如IIa、Xa、XIa、IXa或VIIa抑制剂、血小板活化化合物拮抗剂和选择蛋白拮抗剂,或者2组:
治疗心肌梗塞或中风的药物:
血小板活化或聚集抑制剂,诸如GPIIb/IIIa拮抗剂、凝血酶抑制剂或者Xa因子抑制剂或者ADP受体拮抗剂,
丝氨酸蛋白酶抑制剂,
减少纤维蛋白原的化合物,
选择蛋白拮抗剂,
ICAM-1或VCAM-1拮抗剂,
白细胞粘附抑制剂,
血管壁血细胞外渗抑制剂,
纤维蛋白溶解调节化合物,诸如链激酶、tPA、纤维蛋白溶解酶原活化刺激剂、TAFI抑制剂、XIa抑制剂或PAI-1拮抗剂,
补体因子抑制剂,
内皮素受体拮抗剂,
酪氨酸激酶抑制剂,
抗氧化剂和
白介素8拮抗剂,或者3组:
治疗充血性心力衰竭的药物:
内皮素拮抗剂,
ACE抑制剂,
血管紧张素受体拮抗剂,
内肽酶抑制剂,
β阻滞剂,
钙通道阻滞剂,
磷酸二酯酶抑制剂和
Caspase抑制剂,或者4组:
治疗血管损伤或斯坦特固定模移植后的再狭窄的药物:
凝血酶抑制剂,
Xa因子抑制剂,
引起凝血酶形成的凝血途径的抑制剂,诸如肝素或低分子量肝素,
血小板粘附、活化或聚集抑制剂,诸如GPIIb-IIIa拮抗剂或者vWF或GPIb介导的血小板粘附和活化拮抗剂,
内皮素受体拮抗剂,
氧化氮合成酶抑制剂,
CD44拮抗剂,
选择蛋白拮抗剂,
MCP-1拮抗剂,
增殖细胞中信号转导抑制剂,
EGF、PDGF、VEGF或bFGF介导的细胞反应的拮抗剂和
抗氧化剂,或者5组:
治疗糖尿病性血管病的药物:
EGF、PDGF、VEGF或bFGF介导的细胞反应的拮抗剂,
肝素或低分子量肝素或者其它GAGs,
MMPs抑制剂,
选择蛋白拮抗剂,
内皮素拮抗剂,
ACE抑制剂,
血管紧张素受体拮抗剂和
糖基化抑制剂或AGE形成抑制剂或AGE阻滞剂和它们受体的拮抗剂,诸如RAGE,或者6组:
治疗动脉粥样硬化的药物:
降脂化合物,
选择蛋白拮抗剂,
ICAM-1或VCAM-1的拮抗剂,
肝素或低分子量肝素或者其它GAGs,
MMPs抑制剂,
内皮素拮抗剂,
载脂蛋白A1拮抗剂,
胆固醇拮抗剂,
HMG-CoA还原酶抑制剂,
ACAT抑制剂,
ACE抑制剂,
血管紧张素受体拮抗剂,
酪氨酸激酶抑制剂,
蛋白激酶C抑制剂,
钙通道阻滞剂,
LDL受体功能刺激剂,
抗氧化剂,
LCAT模拟物和
自由基清除剂,或者7组:
治疗癌症的药物,优选抑制肿瘤生长或转移的药物:
抑制细胞生长或抗肿瘤的化合物,
抑制增殖的化合物,诸如激酶抑制剂和
肝素或低分子量肝素或者其它GAGs,或者8组:
治疗骨质疏松症的药物:
抗吸收治疗的化合物,
激素替代治疗的化合物,诸如雌激素或孕酮拮抗剂,
重组人生长激素,
双膦酸酯,诸如阿仑特罗,
用于降钙素治疗的化合物,
降钙素刺激剂,
钙通道阻滞剂,
骨形成刺激剂,诸如生长因子兴奋剂,
白介素6拮抗剂和
Src酪氨酸激酶抑制剂,或者9组:
治疗类风湿关节炎的药物:
TNF拮抗剂,
VLA-4或VCAM-1拮抗剂,
LFA-1、Mac-1或ICAMs拮抗剂,
补体抑制剂,
免疫抑制剂,
白介素-1、白介素-5或白介素-8拮抗剂和
二氢叶酸还原酶抑制剂,或者10组:
促进伤口愈合的药物:
胶原酶,
PDGF拮抗剂和
MMPs。
一种包含至少一种式I化合物、任选的药物赋形剂和取决于适应症的每种情况下选自上述各组中的至少一种其它化合物的药物制剂,是指将至少一种式I化合物与在每种情况下选自上述各组中的至少一种其它化合物和任选的药物赋形剂联合给药。
可通过包含至少一种式I化合物、任选的药物赋形剂和根据上述各组所列的适应症选择的至少一种其它化合物进行联合给药。这种联合给药也可在空间上和/或时间上分开进行。
为了在空间上和/或时间上分开给药,可将这种药物制剂的组分式I化合物和选自上述各组的化合物在空间上和/或时间上分开给药。
治疗血管损伤或斯坦特固定模移植后的再狭窄时,可在相关部位局部单独应用式I化合物,或者与选自4组中的至少一种化合物联合应用。用这些化合物包裹斯坦特固定模也可能是有利的。
治疗骨质疏松症时,式I化合物与抗吸收或激素替代治疗联合应用可能是有利的。
本发明也相应地涉及前面所述药物制剂在制备治疗疾病的药物中的应用。
在一个优选实施方案中,本发明涉及前面所述联合药物制剂在制备治疗疾病的药物中的应用,这些疾病为:
1组化合物所治疗的血小板介导的血管闭塞或血栓,
2组化合物所治疗的心肌梗塞或中风,
3组化合物所治疗的充血性心力衰竭,
4组化合物所治疗的血管损伤或斯坦特固定模移植后的再狭窄,
5组化合物所治疗的糖尿病性血管病,
6组化合物所治疗的动脉粥样硬化,
7组化合物所治疗的癌症,
8组化合物所治疗的骨质疏松症,
9组化合物所治疗的类风湿关节炎,
10组化合物所治疗的伤口愈合。
下列实施例用于说明本发明,但实施例的选择并非是限制性的。I.合成实施例I.A前体实施例1(1-吡啶-2-基哌啶-4-基)甲胺(1)a.)将叔-丁基氧羰基-4-(氨基甲基)-1-哌啶(14g;65.33mmol;由Prugh等,Synthetic Communications 22(16),2361-2365(1992))中的方法制备)溶于50ml THF中,在5℃下,加入6.6g N-甲基吗啉和12.6g氯甲酸苄基酯,并搅拌混合物约2h。浓缩混合物,残余物用CH2Cl2吸收并用饱和NaCl溶液洗涤,干燥并过滤。浓缩后,剩余23.5g黄色油,并将其从甲基叔丁基醚中结晶。18g;ESI-MS[M+H+]=293.15b.)在0℃下,将25ml TFA加入含有叔-丁氧羰基-4-({[(苄基氧)羰基]氨基}甲基)-1-哌啶1a(15g;43.05mmol)的125mlCH2Cl2溶液中,并在10℃下,搅拌混合物20分钟,然后在室温下搅拌20分钟,浓缩混合物并将所得残余物从二乙醚中结晶,得到14.5g游离胺作为TFA盐(ESI-MS[M+H+]=249.25;m.p.:109-110℃。将5g TFA盐和2.79g乙基二异丙胺(DIPEA)加热在15ml 2-氟吡啶中加热回流。反应完成后,浓缩混合物,用乙酸乙酯吸收残余物,并用H2O和饱和NaCl溶液洗涤4次。干燥,过滤,浓缩,得到4.49g淡褐色油,从正戊烷中结晶。4.02g;ESI-MS[M+H+]=362.15c.)在标准条件下,用0.2g Pd(10%在碳上)氢化含有3.9g 1b的150mlCH3OH。将反应混合物经硅藻土过滤并浓缩,得到2.3g;ESI-MS[M+H+]=192.15。1H-NMR(270MHz;DMSO-d6)δ(ppm)8.1(m,1H),7.5(m,1H),6.8(m,1H),6.55(m,1H),4.3(m,2H),2.7(m 2H),2.45(m 2H),1.75(m 2H),1.5(m 1H),1.05(m 2H).实施例2N-(哌啶-4-基甲基)吡啶-2-胺(三氟乙酸盐)(2)a.)将叔丁氧羰基-4-(氨基甲基)-1-哌啶(3g;14mmol和10ml 2-氟吡啶回流4h。浓缩并在正戊烷中研制粗产物,得到3g白色固体,m.p.:126-130℃;ESI-MS[M+H+]=292.15。b.)将1g Boc保护的胺溶于5ml CH2Cl2中,并在0℃下加入10ml TFA后,在室温下搅拌2h。蒸发反应混合物,得到1.9g淡黄色油,它可以直接反应无需进一步提纯;ESI-MS[M+H+]=192.15。实施例3N-[4-(氨基甲基)苄基]吡啶-2-胺(盐酸盐)(3)a.)将2-氨基吡啶(20g;212mmol)溶于100ml CH3OH中,用盐酸异丙醇溶液将pH调至6,加入36.2g(276mmol)对氰基苯甲醛,然后在1小时内将9.3g(148mmol)氰基硼氢化钠分批加入。将黄色悬浮液搅拌过夜,然后浓缩。用100ml水吸收残余物,并用KOH将pH调至>10。用NaCl饱和水相,并用二乙醚提取三次。将醚相过滤,滤液用FeSO4溶液洗涤三次,干燥并浓缩。残余物层析得到40.55g;ESI-MS[M+H+]=210.15。b.)将10g腈3a引入280ml甲醇氨溶液,在加入10g甲醇洗涤的阮内镍后,在室温下氢化28h。过滤和浓缩后所得的残余物,通过在硅胶上层析提纯。将如此获得的主要级分溶于二乙醚,与盐酸异丙醇溶液混合,并结晶过夜。用抽吸滤去所形成的沉淀物,用500ml异丙醇洗涤并煮沸。将产物乘热抽吸滤去并干燥。11.2g;ESI-MS[M+H+]=214.05实施例4[4-(1H-苯并咪唑2-基)-1,3-噻唑-2-基]甲胺(三氟乙酸盐)(4)
通过标准方法从2-(氨基甲基)-1,3-噻唑-4-腈制备用作前体的叔丁基(4-氰基-1,3-噻唑-2-基)甲基氨基甲酸酯(WO 98/067415)a.)将1.89g 30%NaOCH3溶液加入含有叔丁基(4-氰基-1,3-噻唑-2-基)甲基氨基甲酸酯(2.5g;10.45mmol)的25ml CHOH3中,并在室温下搅拌混合物2h。加入1.9g 1,2-苯二胺双盐酸盐后,搅拌过夜,然后将反应混合物加入100ml H2O中,并过滤,并将如此获得的固体真空干燥。3.0g;ESI-MS[M+H+]=331.151H-NMR(400MHz;DMSO-d6)δ(ppm)8.25(s,1H),7.95(m,1H),7.65(m,1H),7.55(m,1H),(m,1H),7.2(m,2H),4.55(m,2H),1.45(s,9H).b.)将1.0g Boc化合物4a溶于10ml CH2Cl2中,并且在0℃下加入10ml TFA后,在室温下搅拌2h。蒸发反应混合物,并用正戊烷研制,得到1.5g作为三氟乙酸盐的胺。Mp.:229-230℃;ESI-MS[M+H+]=231.05实施例5[4-(1H-苯并咪唑2-基)-噻吩-2-基]甲胺(三氟乙酸盐)(5)
通过标准方法从5-(氨基甲基)-3-噻吩腈制备用作前体的叔丁基(4-氰基噻吩-2-基)甲基氨基甲酸酯(WO 98/06741)a.)将3.6g 30%NaOCH3溶液加入含有叔丁基(4-氰基噻吩-2-基)甲基氨基甲酸酯(5g;20.98mmol)的70ml CHOH3中,并在室温下搅拌混合物2h。加入3.6g 1,2-苯二胺双盐酸盐后,搅拌过夜,然后将反应混合物加入50ml H2O中,并用CHCl2提取。干燥并浓缩有机相,得到4.3g黄色固体,它可以通过在硅胶上层析(CH2Cl2/CH3OH 1%→10%)提纯。1.6g;ESI-MS:[M+H+]=333.15b.)将1.5g Boc化合物5a溶于10ml CH2Cl2中,并且在0℃下加入15ml TFA后,在室温下搅拌2h。蒸发反应混合物,并用正戊烷研制,得到1.5g作为三氟乙酸盐的胺。实施例6[4-(1H-苯并咪唑-2-基)苯基]甲胺(三氟乙酸盐)(6)a.)将含有二(叔丁基)-4-氰基苄基亚氨基二碳酸酯(10g;30.08mmol;按Lila等,Synth.Comm.28,23,1998,4419及以下页中的方法制备)的200ml吡啶,与45ml三乙胺混合,在0℃下,用H2S饱和1.5h。反应混合物在室温下静置过夜,然后蒸发。将用此方法获得的残余物用二乙醚研制,用抽吸滤去并干燥(8.5g)。b.)在室温下,用23.2g CH3I将40ml干燥CH2Cl2中的6g硫代酰胺6a(16.37mmol)烷基化过夜,然后蒸发混合物。将用此方法获得的残余物吸收入40mlCH3OH中,加入1.95g 1,2-苯二胺后,再搅拌过夜。蒸发反应混合物并用正戊烷研制此固体,得到6.9g所需的苯并咪唑。Mp.:>170℃(分解);ESI-MS:[M+H+]=424.25c.)将3g双-Boc化合物6b溶于7ml CH2Cl2中,并且在0℃下加入20ml TFA后,在室温下搅拌3h。蒸发反应混合物,并用正戊烷研制,得到3.2g胺(三氟乙酸盐);ESI-MS:[M+H+]=224.05.实施例7[3-(1H-苯并咪唑2-基)苯基]甲胺(三氟乙酸盐)(7)a.)用与Lila等,Synth.Comm.28,23,1998,4419相似的方法,将3-(氯甲基)苄腈(30g;197.9mmol)与二叔丁基亚氨基二羧酸酯反应,以得到二(叔丁基)-3-(1H-苯并咪唑-2-基)苄基亚氨基二碳酸酯。获得65g淡红色油,此油可以使用,无需进一步提纯。b.)用16.5g,用6b中的相似方法,将其转化为硫代酰胺;并用正戊烷将此粗产物研制,得到呈黄色固体的18.1g硫代酰胺。c.)用6c中所述的条件相似的条件,进行烷基化和与1,2-苯二胺的反应;从7.4g硫代酰胺开始,用正戊烷对粗产物进行研制,获得8.5g相应的苯并咪唑。ESI-MS[M+H+]=424.25d.)将7.2g双-Boc化合物7c溶于20ml CH2Cl2中,并且在0℃下加入50mlTFA后,在室温下搅拌3h。蒸发反应混合物,并用甲基叔丁基醚研制,得到3.2g胺(三氟乙酸盐);ESI-MS[M+H+]=224.15.实施例8N-[4-(氨基甲基)苯基]-N’-苄脲(三氟乙酸盐)(8)a.)在0℃下,将三乙胺(6.8g,67.12mmol),然后将二-叔丁基二碳酸酯(18.6g,85.00mmol)加入含有4-氨基苄胺(10.0g,81.85mmol)的150ml CH2Cl2中。混合物在0℃下搅拌1h,然后在室温下搅拌2h。为了处理,加入150ml 1%柠檬酸水溶液,分离相,水相用CH2Cl2(150ml)提取两次。再用水洗涤,用Na2SO4将混合的有机相干燥,并蒸发得到一种固体,与少许二异丙醚一同搅拌,用抽吸滤去并干燥。13.0g;ESI-MS[M+H+-tBu]=167.051H-NMR(360MHz,CDCl3)δ(ppm):7.04(2H,d),6.61(2H,d),4.78(1H,s br.),4.17(2H,d),3.67(2H,s br.),1.46(9H,s).b.)将异氰酸苄基酯(2.40g,18.00mmol)加入一种含有被护胺8a(4.0g,17.99mmol)和三乙胺(1.82g,18.00mmol)的200ml甲苯/DMF 10∶1溶液。反应混合物在室温下搅拌过夜。可以将一部分所形成的脲直接作为沉淀过滤并干燥。滤液用H2O、稀酒石酸洗涤两次至pH为3,用H2O再洗涤两次至pH为5,然后干燥有机相并蒸发。用此方法共获得6.0g;ESI-MS[M+H+-tBu]=300.15。c.)将用此方法所获得的脲8b引入90ml CH2Cl2,并在0℃下,将TFA(2.24g;196.25mmol)-溶于90ml CH2Cl2-滴入。3小时后,加入另外1ml TFA,然后在室温下将混合物搅拌过夜。重复加入1ml TFA后,搅拌混合物5h,然后倒入冰水中,并用乙酸乙酯(2×50ml)提取。用2N NaOH溶液将水相调至碱性,并用CH2Cl2(2×50ml)提取。通过过滤去掉相之间的不溶部分并干燥。4g;ESI-MS[2M+H+]=511.351H-NMR(200MHz,DMSO)δ(ppm):8.52(1H,s),7.39-7.07(9H,m),6.62(1H,t),4.27(2H,d),3.61(2H,s).实施例9N-{[5-(氨基甲基)噻吩-3-基]甲基}吡啶-2-胺(三氟乙酸盐)(9)a.)用NH3将含有叔丁基(4-氰基噻吩-2-基)甲基氨基甲酸酯(7g;29.4mmol)的120ml乙醇溶液饱和,然后在标准条件在阮内镍(9g含水悬浮液;用乙醇倾析)存在下氢化。将反应混合物过滤,蒸发并在硅胶上将所得残余物层析(CH2Cl2/CH3OH加氨水),得到4.4g呈淡黄色油的胺。b.)将1.2胺9a(4.3mmol)、0.6g乙基二异丙胺和15g 2-氟吡啶回流20h。混合物蒸发后所得的残余物用CH2Cl2吸收,用0.1N HCl和饱和的NaCl溶液洗涤,干燥然后再蒸发。1g;ESI-MS[M+H+]=320.15。c.)将0.9g Boc保护的胺9b溶于10ml CH2Cl2中,并在0℃下加入5ml TFA后,在室温下搅拌1h。蒸发反应混合物,得到1.65g淡棕色油,它可以直接反应无需进一步提纯(ESI-MS[M+H+]=220.05)。实施例102-[4-(1H-苯并咪唑-2-基)苯基]乙胺(三氟乙酸盐)(10)a.)在标准条件下,将7g 4-(2-氨基乙基)苄腈转化为相应的Boc衍生物。研制所得的粗产物,得到7.3g白色固体;(ESI-MS[M+H+]=247.15)b.)用与6b中的相似方法,将4g Boc衍生物10a转化为硫代酰胺。并用正戊烷将此粗产物研制,得到4.2g淡黄色固体,然后用与6b的相似方法,将此固体烷基化并与1,2-苯二胺反应,得到苯并咪唑。如此获得的粗产物通过在硅胶上层析(CH2Cl2/CH3OH 4%→50%)提纯。4.8g;ESI-MS[M+H+]=338.15c.)将4.8g Boc保护的胺10b溶于15ml CH2Cl2中,并且在0℃下加入30mlTFA后,在室温下搅拌3h。蒸发反应混合物,并用正戊烷研制,得到7.3g固体。ESI-MS[M+H+]=238.051H-NMR(400MHz,DMSO)δ(ppm):8.30(m,2H,8.0(s br,3H),7.85,7.7和7.55(je m,2H),3.18(m,2H),3.05(m,2H).实施例11N1-吡啶-2-基乙烷-1,2-二胺(11)
用与Nicolaou等;Bioorg.Med.Chem.6(1998),1185-1208的相似方法制备;从100g 2-溴吡啶开始,粗产物蒸馏,得到48.4g。实施例12N1-吡啶-2-基丙烷-1,3-二胺(12)
将2-溴吡啶(100g;0.633mol)和1,3-二氨基丙烷(234.5g;3.16mol)回流7h。反应完成后,蒸发混合物。在真空油泵下蒸馏剩余的残余物,得到43g所需产物。1H-NMR(360MHz,CDCl3)δ(ppm):8.05(d,1H),7.36(t,1H),6.51(t,1H),6.36(d,1H),4.98(s,1H),3.35(s,2H),2.82(t,2H),1.73(m,1H),1.32(s,2H).实施例13N1-甲基-N2-吡啶-2-基乙烷-1,2-二胺(乙酸盐)(13)a.)将2-氨基乙基(甲基)氨基甲酸叔丁酯(2.8g;16.1mmol)和19ml 2-氟吡啶回流约23h。蒸发反应混合物,得到4g褐色油(ESI-MS[M+H+]=252.15),它可以直接进一步反应。b.)将2g 13a的粗产物在30ml TFA中搅拌过夜。蒸发混合物并在RP硅胶上通过MPLC提纯(CH3CN/H2O加0.1%乙酸)。2.2g;ESI-MS[M+H+]=152.1实施例144-(氨基甲基)-N-苄基哌啶-1-甲酰胺a.)将哌啶-4-甲基氨基甲酸苄酯(三氟乙酸盐)(4g;11.04mmol;如对2所述制备)悬浮于60ml甲苯中并与1.43g乙基二异丙胺和异氰酸苄基酯(1.62g;12.14mmol)回流4小时。蒸发反应混合物后的残余物用CH2Cl2吸收并用1N HCl和饱和NaCl溶液提取两次,并将有机相干燥并浓缩。4.2g;ESI-MS[M+H+]=382.25b.)在加热下,将4g苄脲14a溶于乙酸乙酯/CH3OH 3∶1的昆合物中,并且在加入0.2g 10% Pd/活性炭后,在35-40℃标准条件下氢化。反应完成后,混合物通过硅藻土过滤并蒸发。2.8g;ESI-MS[M+H+]=248.151H-NMR(400MHz,DMSO)δppm:7.4-7.15(m,11H),7.05(t,1H),5.08(s,2H),4.25(d,2H),3.95 (d,2H),2.8和2.65(je m,2H),1.6(m,3H),0.95(m,2H).实施例15(5,6-二甲基-1H-苯并咪唑-2-基)甲基氨基甲酸叔丁酯(15)
将1.3g 30% NaOCH3溶液加入含有氰基甲基氨基甲酸叔丁酯(0.4g;25.6mmol)的10ml CH3OH中,并在室温下搅拌混合物1h。加入5.15g 4,5-二氨基-邻-二甲苯双盐酸盐后,将反应混合物搅拌过夜,然后加入100mlH2O中,将通过过滤获得的固体在30℃下真空干燥。0.5g;ESI-MS[M+H+]=276
通过(在标准条件下)用TFA去除Boc基团,获得下面反应所需的胺;然后将分离的TFA盐直接用于相应的偶合反应。实施例16[6-(1H-苯并咪唑-2-基)吡啶-3-基]甲胺(16)a.)用与1的相似方法从(6-氰基吡啶-3-基)甲基氨甲酸叔丁酯(6.0g,25.72mmol)开始制备;从乙醇中结晶粗产物,得到5.15g;ESI-MS[M+H+]=325b.)将含有0.55g Boc保护的胺16a的10ml CH2Cl2,与5ml TFA混合,并在室温下搅拌2h。蒸发反应混合物,得到0.95g白色固体;ESI-MS[M+H+]=225.25实施例173-氨基-N-(1H-咪唑-2-基)丙酰胺(17)a.)Z-β-丙氨酸(10g,44.8mmol)溶于200ml DMF中,并加入15.86g(3.5当量)的N-甲基吗啉和5.9g(0.5当量)的2-氨基咪唑硫酸盐。在-10℃下,加入7.87g(1.3当量)的HOBt和的11.16g(1.3当量)的EDC,并在加热至室温的同时将混合物搅拌1h,然后搅拌18h。加入150ml乙醚,于是沉淀出一种白色固体,并用抽吸将其滤去。用冷乙醚洗涤残余物并悬浮于乙酸乙酯中,并加入1N HCl直至反应为酸性。用乙酸乙酯提取水溶液一次,然后在4℃下,用10% NaOH将水相调至pH为碱性。用抽吸滤去所得沉淀物并用水洗涤。5.4g;ESI-MS[M+H+]=289.05b.)将5.3g Z化合物17a悬浮于250ml乙醇中,并加入530mg 10%在活性碳上的钯。用H2在室温下进行氢化18h,然后用CH3OH稀释后,将悬浮液煮沸,于是产物沉淀溶解。过滤并浓缩溶液,得到1.5g。ESI-MS[M+H+]=155.05实施例184-(氨基甲基)苄基氨甲酸叔丁酯(18)
在0℃下,将24g(111mmol)的二叔丁基碳酸酯滴入含有4-(氨基甲基)苄胺(50.7g;372mmol)1000M CH2Cl2中。在室温下搅拌混合物21h。然后用CH2Cl2稀释,并用5% Na2CO3溶液洗涤,将CH2Cl2相干燥并浓缩。将残余物溶于1N HCl中,并用二乙醚提取两次。用50% NaOH将水相的pH调至10,并用乙酸乙酯提取。将有机相混合、干燥并浓缩。1.48g;ESI-MS[2M+H+]=473.25实施例19N1-吡啶-2-基环己烷-1,2-二胺(19)
将2-溴吡啶(20g;127.6mmol)和72.3g(633mmol)的1,2-二氨基环己烷与15ml吡啶混合,并在120℃下,总共搅拌5×8h并在室温下搅拌2周。在寒冷中变成固体的残余物与正庚烷一起搅拌,用抽吸滤去固体并分离。浓缩母液,用水吸收残余物,并用HCl将pH调至8至9。用CH2Cl2提取溶液,并用水洗涤有机相并浓缩。剩余的油缓慢地结晶,然后与戊烷一同搅拌,用抽吸滤去,并再用甲基叔丁基醚研制,并用抽吸滤去。所得的产物(4.9g)由85%反式化合物和15%顺式化合物组成。13C-NMR(400MHz,CDCl3),δ(ppm)=159.09(Py-C-2/反式),158.46(Py-C-2/顺式),58.19,56.16,35.03,32.74,25.28,25.03(环已烷环/反式),52.28,49.78,32.29,27.75(环己烷环/顺式).实施例20N-[4-(氨基甲基)-1,3-噻唑-2-基]-N’-苄脲(盐酸盐)(20)a.)将一种含有123g吡啶鎓溴化物过溴化物的600ml THF缓慢地滴入含有2-(2-氧代丙基)-1H-异吲哚-1,3(2H)-二酮(70g;0.345mol)的600ml THF中,然后将混合物搅拌大约3h。为了处理,滤去沉淀的固体,浓缩母液,残余物用乙酸乙酯吸收,并将溶液用亚硫酸氢盐水溶液充分洗涤。干燥并浓缩,得到150g黄色油,它是经甲基叔丁基醚研制的。63.4g;m.p.:142-143℃;ESI-MS[M+H+]=283.95b.)在室温下,在70ml THF中搅拌2-(3-溴-2-氧代丙基)-1H-异吲哚-1,3(2H)-二酮20a(6g;21.27mmol)和硫脲(2g;26.27mmol)大约2h。用抽吸滤去沉淀物并干燥。5g;ESI-MS[M+H+]=260.05c.)将2-[(2-氨基1,3-噻唑-4-基)甲基-1H-异吲哚-1,3(2H)-二酮氢溴酸盐20b(4.5g;13.23mmol)、异氰酸苄基酯(1.8g;13.52mmol)和1.7g乙基二异丙胺在50ml甲苯中回流。反应完成后,浓缩混合物,将残余物吸收入CH2Cl2中,并用1N HCl、饱和NaHCO3和NaCl溶液洗涤。干燥并浓缩,得到4.7g桔黄色固体,它是从CH3OH中重结晶的。3.0g;ESI-MS[M+H+]=393.051H-NMR(360MHz,DMSO)δppm:10.65(s,1H),7.9(m,4H),7.25(m,5H),6.85(s,1H),4.7(s,2H),4.35(d,2H),d.)将N-苄基-N’-{4-[(1,3-二氧代-1,3-二氢-2H-异吲哚-2-基)-甲基]-1,3-噻唑-2-基}脲20c(3g;7.64mmol)悬浮于50ml CH3OH中,然后在加入2g水合肼后,在室温下搅拌2h。滤去所得固体,并将所得母液蒸发并用0.5N HCl研制。重新过滤和浓缩母液,以富集所需产物,并因此将此提纯步骤重复三次。0.78g;ESI-MS[M+H+]=263.05实施例21N-(哌啶-4-基甲基)-1H-苯并咪唑-2-胺(三氟乙酸盐)(21)a.)在0℃下,将一种含有叔丁氧基羰基-4-(氨基甲基)-1-哌啶(5.39g;25mmol)的25mlCH3CN滴入含有6.75g硫代羰基二咪唑和0.5g咪唑的100ml CH3CN中,然后在室温下将混合物搅拌3h。然后,加入1,2-苯二胺(5.5g;50.86mmol),并在60℃下加热混合物大约1h。用抽吸滤去冷却所获得的固体并干燥。6.79g;ESI-MS[M+H+-tBu]=309.15b.)将含有4-({[(2-氨基苯胺基)硫代羰基]氨基}甲基)-哌啶-1-甲酸叔丁酯21a(5g;13.72mmol)、5.94g HgO(黄色)和0.6g硫的150ml乙醇溶液回流1h。混合物通过硅藻土过滤两次并蒸发,通过在硅胶上层析(CH2Cl2/CH3OH 5%→25%)将所得的粗产物提纯。2.65g;ESI-MS[M+H+]=331.251H-NMR(360 MHz,DMSO)δppm:7.15和6.9(je m,2H),3.95(d,2H),3.2(m 2H),2.7(br m;2H),1.8(m,1H),1.7(m,2H),1.35(s,9H),1.05(m,2H).c.)在标准条件下,用10ml TFA处理4-[(1H-苯并咪唑-2-基氨基)甲基]哌啶-1-甲酸叔丁酯21b(2.65g;8.02mmol)。浓缩并用正戊烷将粗产物研制,得到2.3g;ESI-MS[M+H+]=231.151H-NR(360MHz,DMSO)δppm:13.25(s,1H),9.35(m,1H),8.8 und 8.5(je br s,1H),7.4和7.20(je m,2H),3.3(m,4H),2.85(m,2H),1.9(m,3H),1.35(m,2H).实施例22a)2-(N-乙酯基硫代氨基甲酰)-1-(N-哌啶子基)-1-丙烯(22a)
在0℃下,将40ml哌啶滴入11.85g(0.2mol)的丙醛和10g的K2CO3中。然后在此温度下搅拌混合物2h,并滤去不溶解的部分,并将滤液在真空下分馏。在冷却的情况下,将N-乙氧羰基异硫氰酸酯(63.7g;0.48mol)滴入含有刚刚蒸馏的1-(N-哌啶子基)丙烯(9.58g;0.077mol)的40ml无水二乙醚的溶液中;在加入过程中,有桔红色沉淀物形成。在0至5℃下,将反应混合物进一步搅拌大约4h,并滤去沉淀,洗涤并干燥。用二乙醚再次处理蒸发母液后所剩余的残余物并过滤。产率:6.81g1H-NMR(400MHz,CDCl3):δ(ppm)7.85(s,1H;CH=C),7.70(br,1H,NH),4.15(q,2H,CH2),3.6(m,4H,哌啶),2.2(s,3H,CH3),1.7(m,6H,哌啶),1.3(t,3H,CH3).b)2-(N-乙酯基硫代氨基甲酰)-1-(N-哌啶子基)-2-苯乙烯(22b)
将15.8ml(0.1mol)的浓度为50%的苯乙醛的邻苯二甲酸二乙酯溶液,与5g K2CO3,在0℃下混合,并且在此温度下,缓慢加入17.04g=19.8ml(0.2mol)的哌啶。在0至5℃下,将反应混合物搅拌1.5h。然后用抽吸将不溶部分滤去,并将母液在浴温度至80℃、真空油泵下蒸馏。在0℃、氮气下,将作为残余物的所得黄色油(27.15g,含有大约50%邻苯二甲酸二乙酯)引入40ml无水二乙醚中。在0℃下,缓慢注入8.1ml=9.02g(80mmol)的N-乙氧基羰基异硫氰酸酯。然后,在0至5℃下,将混合物搅拌4h,大约30分钟后,沉淀出桔黄色固体。在N2下,用抽吸滤去固体,用二乙醚洗涤,并在N2气流下干燥。产率:21.5g黄色固体1H-NMR(400MHz,CDCl3):δ(ppm)8.45(s,1H;CH=C),7.65(br,1H,NH),7.35(m,5H,苯基),4.1(q,2H,CH2),3.1(m,4H,哌啶),1.5(m,6H,哌啶),1.15(t,3H,CH3).下列用与22a的相似方法制备:c)4,4-二甲基-2-(N-乙酯基硫代氨基甲酰)-1-(N-哌啶子基)-1-戊烯(22c)
将从24.03g(0.2mol)的4,4-二甲基戊醛、10g k2CO3和39.6ml哌啶中获得的烯胺,与7.68ml(65.1mmol)的N-乙氧基羰基异硫氰酸酯反应。产率:黄色固体8.86g。1H-NMR(270MHz,CDCl3):δ(ppm)7.95(br,1H,NH),7.52(s,1H;CH=C),4.17(q,2H,CH2),3.46(m,4H,哌啶),2.83(s,2H,CH2),1.66(m,6H,哌啶),1.28(t,3H,CH3),0.95(s,9H,3*CH3).d)2-(N-乙酯基硫代氨基甲酰)-1-(N-哌啶子基)-1-戊烯(22d)
将从17.23g(0.2mol)的戊醛、10g k2CO3和39.6ml哌啶中获得的烯胺,与8.84ml(74.9mmol)的N-乙氧基羰基异硫氰酸酯反应。产率:深黄色固体15.15g。1H-NMR(270MHz,CDCl3):δ(ppm)7.77(br,1H,NH),7.52(s,1H;CH=C),4.15(q,2H,CH2),3.5(m,4H,哌啶),2.7(t,2H,CH2),1.7(m,6H,哌啶),1.55(m,2H,CH2),1.3(t,3H,CH3),0.95(t,3H,CH3).e)2-(N-乙酯基硫代氨基甲酰)-2-(四氢-2H-吡喃-4-基)-1-(N-哌啶子基)乙烯(22e)
将从25.84g(0.2mol)的4-甲酰基甲基四氢吡喃、10g k2CO3和39.6ml哌啶中获得的烯胺,与10.1ml(85.6mmol)的N-乙氧基羰基异硫氰酸酯反应。产率:黄色固体27g。1H-NMR(270MHz,CDCl3):δ(ppm)8.2(br,1H,NH),6.84(s,1H;CH=C),4.15(q,2H,CH2),3.95和3.5(分别m,2H,THP-OCH2),3.2(m,4H,哌啶-NCH2),2.65(m,1H,THP-CH),1.65-1.95(m,10H,哌啶-CH2和THP-CH2),1.3(t,3H,CH3).实施例232-(哌啶-4-基氨基)吡啶(23)a)将4-氨基-1-哌啶羧酸乙基酯(6g;34.8mmol)和25g的2-氟吡啶回流48h。用抽吸滤去冷却后所形成的固体,用正戊烷研制并干燥;6.26g黄色粉末;ESI-MS[M+H+]=250.15。b)将6g 4-(吡啶-2-基氨基)哌啶-1-羧酸乙基酯(23a)在30ml 47%HBr中回流6h。蒸发混合物,用乙酸乙酯/CH3OH(9∶1)研制所得的粗产物并重新干燥,得到7.1g白色固体;ESI-MS[M+H+]=178.15。实施例24N-[4-(氨基甲基)-苯基]-1H-苯并咪唑-2-胺(三氟乙酸盐)(24)a)用与21a的相似方法,将4-氨基苄基氨甲酸叔丁基酯(5g;22.5mmol)与6g硫代羰基二咪唑、0.3g咪唑和4.86g 1,2-苯二胺反应。用此方法获得的粗产物,通过在硅胶上层析(CH2Cl2/CH3OH 2→10%)提纯。8.2g油;ESI-MS[M+H+]=373.151H-NMR(360MHz,DMSO)δppm:9.5和9.05(je s,1H),7.45(d,2H),7.35(m,1H),7.20(d,1H),7.15,6.95,6.75,6.60(je m,1H),4.85(s,2H),4.10(d,2H),1.35(s,9H).b)用与21c相似的方法,将4-{[(2-氨基苯胺基)硫代羰基]氨基}苄基-氨甲酸叔丁基酯(4.3g;11.54mmol)、5g HgO(黄色)和0.05g硫在150ml乙醇中回流。通过硅藻土将反应混合物过滤并浓缩,得到2.1g深色固体(ESI-MS[M+H+]=339.15)。无需进一步纯化,在室温下,用15ml TFA处理从此方法中获得的4-(1H-苯并咪唑-2-基氨基)苄基-氨甲酸叔丁基酯2h,并浓缩,得到4.7g深色油,它可以进一步反应,无需进一步提纯(ESI-MS[M+H+]=239.05)。1H-NMR(360MHz,DMSO)δppm:11.25(s,1H),8.25(s 宽,2-3H),7.60(m,4H),7.40(m,2H),7.30(m 2H),4.15(m,2H).实施例25[5-(1-苯并咪唑-2-基)噻吩-2-基]甲胺(25)a)将5-(氨基甲基)噻吩-2-腈(25g;146mmol)(如WO 95/23609中所述制备)溶于750ml CH2Cl2中,并加入50ml乙基二异丙胺。在冰中冷却的同时,将二叔丁基二碳酸酯(35.05g;160mmol)加入此溶液中。16h后,用10%柠檬酸洗涤4次,用饱和NaHCO3溶液洗涤2次,用饱和NaCl溶液洗涤1次。干燥有机相并浓缩。(38.2g)b)将(5-氰基噻吩-2基)甲基氨甲酸叔丁基酯(25g)溶于甲醇中,并加入19.3ml浓度为30%的甲醇钠的甲醇溶液。16h后,再加入1.9ml甲醇钠溶液,并将混合物加热至40-50℃。2h后,将混合物冷却至室温并加入1,2-苯二胺盐酸盐。3天后,冷却悬浮液并与250ml水混合,并用抽吸滤去沉淀。固体用水洗涤并干燥(19.6g)。将9.5g的此沉淀悬浮于400mlCH2Cl2中,并在室温下,加入22mlTFA。16h后,浓缩混合物,将残余物溶于水并用二乙醚提取2次,并将水相的pH调至10-11,然后用乙酸乙酯提取2次。水相用NaCl饱和并用乙酸乙酯再次提取。干燥混合的有机相并浓缩。6.3g;ESI-MS[M+H+]=230.1实施例263-[(5,6-二甲基-1H-苯并咪唑-2-基)氨基]-3-氧代丙-1-胺(盐酸盐)(26)
Boc-β-丙氨酸(1.89g;10mmol)溶于15ml DMF中,在加入2.02g N-甲基吗啉、0.122g二甲基氨基吡啶和1.92g EDC*HCl后,搅拌1h。向澄清溶液中加入1.93g(12mmol)的2-氨基-5,6-二甲基苯并咪唑,并在室温下搅拌16h,然后在60℃下搅拌1h。反应完成后,加入NaCl溶液,然后用乙酸乙酯提取2次,有机相用10%柠檬酸洗涤2次并用水洗涤2次,干燥并浓缩。将残余物(1.3g)溶于10ml CH2Cl2中,并加入10ml TFA。2h后,蒸发混合物,用二乙醚吸收残余物,加入HCl乙醚溶液。1h后,用抽吸滤去结晶,洗涤至中性并在40℃下干燥。0.90g;ESI-MS[M+H+]=233.21H-NMR(270MHz,DMSO-d6)δppm=8.3(bs,3H),7.45(s,2H),3.25-3.0(m,4H),2.35(s,6H).实施例273-[(1H-苯并咪唑-2-基)氨基]-3-氧代丙-1-胺(盐酸盐)(27)
用与26相似的制备方法,从(1.60g;12mmol)的2-氨基苯并咪唑开始合成。1H-NMR(270MHz;DMSO-d6)δppm:8.3(bs,3H),7.7(m,2H),7.4(m,2H),3.15(m,2H),3.10(m,2H).实施例282-[(哌啶鎓-4-基羰基)氨基]-1H-苯并咪唑(双三氟乙酸盐)(28)
将含有Boc-异3-哌啶甲酸(3.0g;13.08mmol)的10ml CH2Cl2与13.4ml乙基二异丙胺和1.74g(13.08mmol)2-氨基吡啶混合。在冷却至4℃后,滴入15.4ml 50%的丙烷膦酸酐溶液,并将混合物搅拌1.5h。然后在室温下,搅拌混合物4h,然后浓缩并用乙酸乙酯吸收。溶液用稀NaOH、水和10%浓度的柠檬酸提取并用饱和的NaCl溶液提取3次。干燥并浓缩有机相,残余物从二乙醚(1.30g)中结晶。将1.25g沉淀溶于15ml CH2Cl2中,并加入15ml TFA。3h后,浓缩混合物并将残余物从二乙醚中结晶。冷却至0℃后,用抽吸滤去残余物并干燥。1.20g;ESI-MS[M+H+]=245.2实施例29N-吡啶-2-基哌啶-4-甲酰胺(双三氟乙酸盐)(29)
用与28的相似方法,从1.23g(13.08mmol)的2-氨基吡啶开始制备。所得产物是吸湿性的,通过与甲苯共馏干燥。0.72g;ESI-MS[M+H+]=206.2实施例30N-[4-(氨基甲基)-1,3-噻唑-2-基]吡啶-2-胺(盐酸盐)(30)a)2-氨基吡啶(11g;116.9mmol)和异硫氰酸苄基酯(21g;128.7mmol)在250ml丙酮中回流3h。蒸发混合物并将所得残余物首先用丙酮/正戊烷,然后只用正戊烷研制。21.4g;ESI-MS[M+H+]=258.05b)将N-苯甲酰基-N’-吡啶-2-基硫脲(30a)(5g;19.43mmol)引入100ml丙酮/CH3OH混合物中,并在加入含有1.34g K2CO3的5ml H2O后,回流2h。为了处理,滤去所形成的沉淀,蒸发母液,并将所得残余物加入H2O中。用CH2Cl2提取、干燥和蒸发有机相,得到5.4g;ESI-MS[M+H+]=154.051H-NMR(270MHz,DMSO-d6)δppm:10.65(s,1H),10.55(s,1H),8.9(s,1H),8.25,7.75,7.20,7.10(je m,1H).c)在室温下,将N-吡啶-2-基硫脲(30b)(5g;35.9mmol)和2-(3-溴-2-氧代丙基)-1H-异吲哚-1,3-(2H)-二酮在500ml THF中搅拌2h。滤去所形成的沉淀并干燥。12.3g白色固体;ESI-MS[M+H+]=337.05。d)用与20d的相似方法,从2-{[2-(吡啶-2-基氨基)-1,3-噻唑-4-基]-甲基}-1H-异吲哚-1,3(2H)-二酮(30c)(10g;23.96mmol)和含有7g水合肼的250ml CH3OH开始,去除邻苯二甲酰基团。随后处理,得到4.15g黄色固体;ESI-MS[M+H+]=207.05。实施例314-[(1,4,5,6-四氢嘧啶-2-基氨基)甲基]哌啶(三氟乙酸盐)(31)
在室温下,将叔丁氧羰基-4-(氨基甲基)-1-哌啶(2g;9.33mmol)、2-(甲基硫基)1,4,5,6-四氢嘧啶-1-鎓碘化物(2.41g;9.33mmol)和1.2g乙基二异丙胺,在10ml DMF中搅拌24h。蒸发混合物,加入甲苯/丙酮,滤去所得固体,并将滤液再次蒸发。获得褐色油作为粗产物(ESI-MS[M+H+]=297.25),它可以直接用10ml TFA处理,无需进一步提纯。蒸发反应混合物,得到深褐色油,它可以通过MPLC(硅胶:BischoffProntoprep 60-2540-C18E,32mm;洗脱液:CH3CN/H2O+0.1%乙酸)提纯(1.36g油)实施例32[4-(吡啶-2-基氨基)苯基]甲胺(盐酸盐)(32)
将4-氨基苄基氨基甲酸叔丁基酯(4g;17.99mmol)和17.5g 2-氟吡啶回流32h。反应完成后,蒸发混合物,并将残余物用正戊烷研制。将此方法所获得的粗产物(5.3g)溶于100ml CH2Cl2中,并在0℃下,加入6.9mlTFA。3.5h后,蒸发混合物,残余物用二乙醚吸收,并加入HCl乙醚溶液。用抽吸滤去并干燥沉淀,得到3.3g相应的盐酸盐。M.p.:208℃(分解);ESI-MS[M+H+]=200.15。I.B.通式I的化合物实施例I-1乙酸4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)-1-吡啶-2-基哌啶鎓(I-1)a)用DMF中的哌啶(50%),将1.5g Z-Dap(Fmoc)-2-Cl-三苯甲基树脂(0.6mmol;取代0.4mmol/g树脂)处理20分钟。用DMF洗涤(5*1分钟)后,将树脂悬浮于6ml DMF中,并在加入430mg 2-(N-乙酯基硫代氨基甲酰)-1-(N-哌啶子基)-3-丙烯(22a)后,在室温下恒温过夜。然后,用DMF、MeOH、CH2Cl2和NMP洗涤。在4.5ml NMP中的树脂的悬浮液与含有1.83g Cs2CO3的0.89ml的H2O和0.56ml的5M BrCN的CH3CN溶液混合。在室温下恒温6h,然后用抽吸过滤并用NMP和CH2Cl2洗涤。b)将用此方法获得的0.037mmol的树脂悬浮于3.5ml NMP中,并在加入27μl DIPEA后,与14.2mg(1-吡啶-2-基哌啶-4-基)甲胺混合。恒温过夜后,用抽吸过滤并用DMF、H2O、DMF、CH2Cl2、MeOH和CH2Cl2洗涤。用1.5ml三氟乙醇/冰醋酸/CH2Cl2(1h,室温),使产物从树脂解离。过滤后蒸发,用2ml冰醋酸吸收并冷冻干燥。产率:22mgESI-MS[M+H+]:521(计算值:521)。实施例I-2乙酸2-{4-[1-(2-{[(苄氧基)羰基]氨基}-2-羧乙基)-2-氧代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]哌嗪-1基}吡啶鎓(I-2)
将55mg Z-Dap-2-Cl-三苯甲基树脂(0.04mmol)悬浮于2ml DMF中,并加入3当量的22e。恒温过夜后,用DMF、MeOH、CH2Cl2和NMP洗涤。然后将树脂悬浮于NMP中,并加入含有131mg Cs2CO3的63μl的H2O和40μl的5M BrCN的CH3CN溶液。在室温下恒温6h,然后用抽吸过滤并用NMP和CH2Cl2洗涤。将所得树脂悬浮于3.5ml NMP中,并在加入28μlDIPEA后,与13.1mg 1-(2-吡啶基)哌嗪混合。恒温过夜后,用抽吸过滤并用DMF、H2O、DMF、CH2Cl2、MeOH和CH2Cl2洗涤。用1.5ml三氟乙醇/冰醋酸/CH2Cl2(1h,室温),使产物从树脂解离。过滤后蒸发,用2ml冰醋酸吸收并冷冻干燥。产率:24mgESI-MS[M+H+]:563(计算值:563)。实施例I-33-(4-[4-(苯胺基羰基)哌嗪-1-基]-5-甲基-2-氧代嘧啶-1(2H)-基)-N-[(苄基氧基)羰基]丙氨酸(I-3)a)将0.28mmol实施例I-1a)中所获得的树脂加入含有192.6μl(1.12mmol)DIPEA和2.4g哌嗪(哌嗪没有完全溶解,滤去不溶部分)的15ml的NMP溶液。恒温过夜后,用抽吸过滤并用DMF、H2O、DMF、CH2Cl2、MeOH和CH2Cl2洗涤。b)将0.04mmol用此方法获得的树脂悬浮于CH2Cl2中,并在加入0.08mmol异氰酸苯基酯后,在室温下恒温过夜。用1.5ml三氟乙醇/冰醋酸/CH2Cl2(1h,室温),使产物从树脂解离。过滤后蒸发,用2ml冰醋酸吸收并冷冻干燥。产率:11mgESI-MS[M+H+]:535(计算值:535)。实施例I-4三氟乙酸2-{[(1-{1-[2-羧基-1-(4-甲基苯基)乙基]-5-甲基-2-氧代-1,2-二氢嘧啶-4-基}哌啶-4-基)甲基]氨基}吡啶鎓(I-4)
用与实施例I-1a)的相似方法,使0.037mmol的D,L-3-氨基-3-(4-甲基苯基)丙酸-2-Cl-三苯甲基树脂发生反应,并然后悬浮于3.5ml的NMP中。加入68μl DIPEA和21.7mg的N-(哌啶-4-基甲基)吡啶-2-胺(三氟乙酸盐),然后在室温下恒温过夜。用抽吸过滤后并用DMF、H2O、DMF、CH2Cl2、MeOH和CH2Cl2洗涤。用1.5ml三氟乙醇/冰醋酸/CH2Cl2(1h,室温),使产物从树脂解离。过滤后蒸发,用2ml冰醋酸吸收并冷冻干燥。通过RP-HPLC将粗产物提纯。产率:5mgESI-MS[M+H+]:462(计算值:462)。实施例I-5乙酸2-[(2-{[1-(4-羧基丁基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}乙基)氨基]吡啶鎓(I-5)
用与实施例I-1a)的相似方法,使0.04mmol的5-氨基戊酸-2-Cl-三苯甲基树脂发生反应,向所得树脂的3.5ml的NMP的悬浮液中,加入28μlDIPEA和11mg的N1-吡啶-2基乙烷-1,2-二胺。在室温下恒温过夜,然后用抽吸过滤并用DMF、H2O、DMF、CH2Cl2、MeOH和CH2Cl2洗涤。用1.5ml三氟乙醇/冰醋酸/CH2Cl2(1h,室温),使产物从树脂解离。过滤后蒸发,用2ml冰醋酸吸收并冷冻干燥。产率:16mgESI-MS[M+H+]:346(计算值:346)。类似地制备下列化合物:实施例I-6   乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌嗪-1-基}-6-甲基吡啶鎓ESI-MS[M+H]+:507(计算值:507)I-7   乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:493(计算值:493)I-8   乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:493(计算值:493)I-9   二乙酸1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-4-吡嗪-4-鎓-2-基哌嗪-4-鎓ESI-MS[M+H]+:494(计算值:494)I-10  二乙酸1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-5-甲
  基-2-氧代-1,2-二氢嘧啶-4-基]-4-(吡啶鎓-4-基甲基)哌嗪-4-
  鎓ESI-MS[M+H]+:507(计算值:507)I-11  二乙酸4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-5-甲
  基-2-氧代-1,2-二氢嘧啶4-基]-1-(3-吡咯烷鎓-1-基丙基)-
  1,4-diazepan-1-鎓ESI-MS[M+H]+:541(计算值:541)I-12  3-(4-{4-[(苄氨基)羰基]哌嗪-1-基}-5-甲基-2-氧代嘧啶-
  1(2H)-基)-N-[(苄氧基)羰基)丙氨酸ESI-MS[M+H]+:549(计算值:549)I-13  乙酸2-[(2-{[1-((2S)2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:467(计算值:467)I-14  乙酸2-[(2-{[1-(4-{[(苄氧基)羰基]氨基}-4-羧基-丁基)-5-甲
  基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:495(计算值:495)I-15  乙酸2-[(2-{[1-(5-{[(苄氧基)羰基]氨基}-5-羧基-戊基)-5-甲
  基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:509(计算值:509)I-16  乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-2-
  氧代-5-苯基-1,2-二氢嘧啶-4-基]-哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:555(计算值:555)I-17  乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-5-
  新戊基-2-氧代-1,2-二氢嘧啶-4-基]-哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:549(计算值:549)I-18  乙酸2-{4-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙基)-2-
  氧代-5-丙基-1,2-二氢嘧啶-4-基]-哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:521(计算值:521)I-19  3-(4-[4-(苯胺羰基)-1,4-diazepan-1-基]-5-甲基-2-氧代嘧啶-
  1(2H)-基)-N-[(苄氧基)羰基]丙氨酸ESI-MS[M+H]+:549(计算值:549)I-20  乙酸2-{4-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基-
  2-氧代-1,2-二氢嘧啶-4-基]哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:507(计算值:507)I-21  乙酸2-{4-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-氧代-
  5-苯基-1,2-二氢嘧啶-4-基]哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:569(计算值:569)I-22  乙酸2-{4-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-氧代-
  5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:577(计算值:577)I-23  乙酸2-{4-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-氧代-
  5-丙基-1,2-二氢嘧啶-4-基]哌嗪-1-基}吡啶鎓ESI-MS[M+H]+:535(计算值:535)I-24  乙酸2-[(2-{{1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基
  -2-氧代-1,2-二氢嘧啶-4-基]氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:481(计算值:481)I-25  乙酸2-[(2-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-氧代
  -5-苯基-1,2-二氢嘧啶-4-基]氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:543(计算值:543)I-26  乙酸2-[(2-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基-丙基)-2-氧
  代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]氨基}乙基)氨基]
  吡啶鎓ESI-MS[M+H]+:551(计算值:551)I-27  乙酸2-[(2-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-氧代
  -5-丙基-1,2-二氢嘧啶-4-基]-氨基}乙基)氨基]吡啶鎓ESI-MS[M+H]+:509(计算值:509)I-28  3-(4-[(6-{[(苄氨基)羰基]氨基}己基)氨基]-5-甲基-2-氧代嘧
  啶-1(2H)-基)-N-[(苄氧基)羰基]丙氨酸ESI-MS[M+H]+:579(计算值:579)I-29  乙酸2-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基]氨基}甲基)-5,6-二甲基-1H-苯并咪唑
  -1-鎓ESI-MS[M+H]+:519(计算值:519)I-30  二乙酸2-[5-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲
  基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)吡啶鎓-2-基]-3H-苯
  并咪唑-1-鎓ESI-MS[M+H]+:568(计算值:568)I-31  三氟乙酸4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲
  基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)-1-吡啶-2-基哌啶鎓ESI-MS[M+H]+:535(计算值:535)I-32  乙酸[4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基-
  2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)苯基]甲铵ESI-MS[M+H]+:480(计算值:480)I-33  (2S)-3-(4-[({1-[(苄氨基)羰基]哌啶-4-基}甲基)氨基]-5-甲基
  -2-氧代嘧啶-1(2H)-基)-2-{[(苄氧基)羰基]氨基}丙酸ESI-MS[M+H]+:577(计算值:577)I-34  三氟乙酸2-[2-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基-丙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}甲基)-1,3-噻唑-4-
  基)-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:574(计算值:574)I-35  三氟乙酸N-(2-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基-丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}环己基)吡啶-2-铵ESI-MS[M+H]+:535(计算值:535)I-36  二三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基-丙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨]
  吡啶鎓ESI-MS[M+H]+:535(计算值:535)I-37  三氟乙酸2-[2-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-甲基)-1,3-噻唑
  -4-基]-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:560(计算值:560)I-38  三氟乙酸N-(2-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-环己基)吡啶-2-
  铵ESI-MS[M+H]+:521(计算值:521)I-39  三氟乙酸2-[5-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基-乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-甲基)噻吩-3-
  基]-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:559(计算值:559)I-40  三氟乙酸2-[({1-[1-((2S)-2-{[(苄氧基)羰基]-氨基}-2-羧基-
  乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]哌啶-4-基}甲基)氨
  基]吡啶鎓ESI-MS[M+H]+:521(计算值:521)I-41  三氟乙酸2-({2-[[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-(甲基)氨基]乙基}氨基)吡啶
  鎓ESI-MS[M+H]+:495(计算值:495)I-42  三氟乙酸2-({2-[[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基](甲基)-氨基]乙基}氨
  基)吡啶鎓ESI-MS[M+H]+:481(计算值:481)I-43  乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-丙酰基)氨基]-1H-咪
  唑-1-鎓ESI-MS[M+H]+:483(计算值:483)I-44  乙酸2-{[3-({1-[2-羧基-1-(4-甲基苯基)乙基]-5-甲基-2-氧代-
  1,2-二氢嘧啶-4-基}氨基)丙酰基]氨基}-4H-咪唑-3-鎓ESI-MS[M+H]+:425(计算值:425)I-45  乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基
  -2-氧代-1,2-二氢嘧啶-4-基]氨基}-丙酰基)氨基]-1H-咪唑-1-
  鎓ESI-MS[M+H]+:498(计算值:498)I-46  乙酸2-[(4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)苄基)氨基}吡啶
  鎓ESI-MS[M+H]+:543(计算值:543)I-47  (3S)-4-(4-[(4-{[(苄氨基)羰基]氨基}苄基)氨基]-5-甲基-2-氧
  代嘧啶-1(2H)-基)-3-{[(苄氧基)羰基]氨基}丁酸ESI-MS[M+H]+:599(计算值:599)I-48  4-(4-{[4-(1H-苯并咪唑-2-基)苄基]氨基}-5-甲基-2-氧代嘧啶-
  1(2H)-基)-3-{[(苄氧基)羰基]氨基}丁酸ESI-MS[M+H]+:567(计算值:567)I-49  (2S)-3-(4-{[(2-(苄氨基)羰基]氨基}-1,3-噻唑-4基)甲基]氨
  基}-5-甲基-2-氧代嘧啶-1(2H)-基)-2-{[(苄氨基)羰基]氨基}丙
  酸ESI-MS[M+H]+:592(计算值:592)I-50  4-(4-{[(2-{[(苄氨基)羰基]氨基}-1,3-噻唑-4-基)甲基]氨基}-
  5-甲基-2-氧代嘧啶-1(2H)-基)-3-{[(苄氧基)羰基]氨基}丁酸ESI-MS[M+H]+:606(计算值:606)I-51  (2S)-3-(4-{[3-(1H-苯并咪唑-2-基)苄基]氨基}-5-甲基-2-氧代
  嘧啶-1(2H)-基)-2-{[(苄氨基)羰基]氨基}丙酸ESI-MS[M+H]+:553(计算值:553)I-52  (2S)-3-(4-{[4-(1H-苯并咪唑-2-基)苄基]氨基}-5-甲基-2-氧代
  嘧啶-1(2H)-基)-2-{[(苄氨基)羰基]氨基}丙酸ESI-MS[M+H]+:553(计算值:553)I-53  (2S)-3-(4-[(4-{[(苄氨基)羰基]氨基}苄基)氨基]-5-甲基-2-氧
  代吡啶-1(2H)-基)-2-{[(苄氧基)羰基]氨基}丙酸ESI-MS[M+H]+:585(计算值:585)I-54  三氟乙酸2-{[4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)苄基]氨基}吡啶
  鎓ESI-MS[M+H]+:557(计算值:557)I-55  三氟乙酸2-{4-[({1-[2-羧基-1-(4-甲基苯基)乙基]-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基}氨基)甲基]苯基}-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:494(计算值:494)I-56  3-(4-[(4-{[(苄氨基)羰基]氨基}苄基)氨基]-5-甲基-2-氧代嘧
  啶-1(2H)-基)-3-(4-甲苯基)-丙酸ESI-MS[M+H]+:526(计算值:526)I-57  3-(4-{[(2-{[(苄氨基)羰基]氨基}-1,3-噻唑-4-基)甲基]氨基}-
  5-甲基-2-氧代嘧啶-1(2H)-基)-3-(4-甲苯基)丙酸ESI-MS[M+H]+:533(计算值:533)I-58  三氟乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-2-氧代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]氨基}丙
  酰基)氨基]-1H-咪唑-1-鎓ESI-MS[M+H]+:554(计算值:554)I-59  三氟乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-2-氧代-5-丙基-1,2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-
  1H-咪唑-1-鎓ESI-MS[M+H]+:512(计算值:512)1-60  三氟乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-2-氧代-5-苯基-1, 2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-
  1H-咪唑-1-鎓ESI-MS[M+H]+:546(计算值:546)I-61  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]氨基}丙酰基)
  氨基]-1H-咪唑-1-鎓ESI-MS[M+H]+:568(计算值:568)I-62  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-丙基-1,2-二氢嘧啶-4-基]氨基}-丙酰基)氨基]-1H-咪唑
  -1-鎓ESI-MS[M+H]+:526(计算值:526)I-63  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-苯基-1,2-二氢嘧啶-4-基]氨基}-丙酰基)氨基]-1H-咪唑
  -1-鎓ESI-MS[M+H]+:560(计算值:560)I-64  三氟乙酸2-[({1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-2-氧代-5-丙基-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨基]
  吡啶鎓ESI-MS[M+H]+:549(计算值:549)I-65  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲
  基)氨基]吡啶鎓ESI-MS[M+H]+:605(计算值:605)I-66  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-丙基-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨基]吡啶
  鎓ESI-MS[M+H]+:563(计算值:563)I-67  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-2-
  氧代-5-苯基-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨基]吡啶
  鎓ESI-MS[M+H]+:597(计算值:597)I-68  乙酸2-{[4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  2-氧代-5-四氢-2H-吡喃-4-基-1,2-二氢嘧啶-4-基]氨基}甲基)
  苄基]氨基}吡啶鎓ESI-MS[M+H]+:613(计算值:613)I-69  (2S)-3-(4-[(4-{[(苄氧基)羰基]氨基}苄基)-氨基]-2-氧代-5-
  四氢-2H-吡喃-4-基嘧啶-1(2H)-基]-2-{[(苄基氧)羰基]氨基}丙
  酸ESI-MS[M+H]+:655(计算值:655)I-70  乙酸2-{[4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  2-氧代-5-丙基-1,2-二氢嘧啶-4-基]氨基}甲基)苄基)氨基}吡啶
  鎓ESI-MS[M+H]+:571(计算值:571)I-71  3-(4-[(4-{[(苄氨基)羰基]氨基}苄基)氨基]-2-氧代-5-丙基嘧
  啶-1(2H)-基)-N-[(苄氧基)羰基]丙氨酸ESI-MS[M+H]+:613(计算值:613)I-72  乙酸2-[({1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]哌啶-4-基}甲基)氨基]-1H-
  苯并咪唑-1-鎓ESI-MS[M+H]+:560(计算值:560)I-73  三氟乙酸2-[3-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}甲基)苯基]-1H-苯并咪
  唑-1-鎓ESI-MS[M+H]+:567(计算值:567)I-74  三氟乙酸2-({[4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-
  5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-甲基)噻吩-3-基]甲
  基}氨基)吡啶鎓ESI-MS[M+H]+:563(计算值:563)I-75  三氟乙酸2-{4-[2-({1-[2-羧基-1-(4-甲苯基)乙基]-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基}氨基)乙基]苯基}-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:508(计算值:508)I-76  三氟乙酸2-[({4-[({1-[2-羧基-1-(4-甲苯基)乙基]-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基}氨基)甲基]噻吩-3-基}-甲基)氨基]
  吡啶鎓ESI-MS[M+H]+:490(计算值:490)I-77  三氟乙酸2-[3-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}-甲基)苯基]-1H-
  苯并咪唑-1-鎓ESI-MS[M+H]+:553(计算值:553)I-78  三氟乙酸2-[4-(2-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基
  乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}乙基)苯基]-
  1H-苯并咪唑-1-鎓ESI-MS[M+H]+:567(计算值:567)I-79  三氟乙酸2-({[4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基
  乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)噻吩-3-
  基]甲基}氨基)吡啶鎓ESI-MS[M+H]+:549(计算值:549)I-80  三氟乙酸2-({4-[({1-[2-羧基-1-(4-甲基苯基)乙基]-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基}氨基)甲基]苄基}氨基)吡啶鎓ESI-MS[M+H]+:484(计算值:484)I-81  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨基]-1H-
  苯并咪唑-1-鎓ESI-MS[M+H]+:574(计算值:574)I-82  三氟乙酸2-{[(1-{1-[2-羧基-1-(4-甲基苯基)乙基]-5-甲基-2-
  氧代-1,2-二氢嘧啶-4-基}哌啶-4-基)甲基]氨基}-1H-苯并咪唑-
  1-鎓ESI-MS[M+H]+:501(计算值:501)I-83  三氟乙酸2-{[4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-2-氧代-5-苯基-1,2-二氢嘧啶-4-基]氨基}甲基)苄基]氨基}
  吡啶鎓ESI-MS[M+H]+:605(计算值:605)I-84  (2S)-3-(4-[(4-{[(苄氨基)羰基]氨基}苄基)氨基]-2-氧代-5-苯
  基嘧啶-1(2H)-基)-2-{[(苄氧基)羰基]氨基}丙酸ESI-MS[M+H]+:647(计算值:647)I-85  4-(4-{[(2-{[(苄氨基)羰基]氨基}-1,3-噻唑-4-基)甲基]氨基}-
  2-氧代-5-四氢-2H-吡喃-4-基-嘧啶-1(2H)-基)-3-{[(苄氧基)羰
  基]氨基}丁酸ESI-MS[M+H]+:676(计算值:676)I-86  4-(4-{[(2-{[(苄氨基)羰基]氨基}-1,3-噻唑-4-基)甲基]氨基}-
  2-氧代-5-丙基嘧啶-1(2H)-基)-3-{[(苄氧基)羰基]氨基}丁酸ESI-MS[M+H]+:634(计算值:634)I-87  4-(4-{[(2-{[(苄氨基)羰基]氨基}-1,3-噻唑-4-基)甲基]氨基}-
  2-氧代-5-苯基嘧啶-1(2H)-基)-3-{[(苄氧基)羰基]氨基}丁酸ESI-MS[M+H]+:668(计算值:668)I-88  三氟乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
  基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙基)氨基]吡啶
  鎓ESI-MS[M+H]+:481(计算值:481)I-89  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙基)氨基]吡啶鎓ESI-MS[M+H]+:495(计算值:495)I-90  三氟乙酸2-{[3-({1-[2-羧基-1-(4-甲苯基)乙基]-5-甲基-2-氧
  代-1,2-二氢嘧啶-4-基}氨基)丙基]氨基}吡啶鎓ESI-MS[M+H]+:422(计算值:422)I-91  三氟乙酸2-[4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
  甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)苯基]-3H-苯并咪
  唑-1-鎓ESI-MS[M+H]+:567(计算值:567)I-92  乙酸2-[({1-[1-(2-羟基乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
  基]哌啶-4-基}甲基)氨基]吡啶鎓ESI-MS[M+H]+:372(计算值:372)I-93  乙酸2-[({1-[1-(3-羧基丙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
  基]哌啶-4-基}甲基)氨基]吡啶鎓ESI-MS[M+H]+:386(计算值:386)I-94  乙酸2-[({1-[1-(2-羧基乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
   基]哌啶-4-基}甲基)氨基]-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:411(计算值:411)I-95   乙酸2-[({1-[1-(3-羧基丙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
   基]哌啶-4-基}甲基)氨基]-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:425(计算值:425)I-96   乙酸2-[(3-{[1-(2-羧基乙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
   基]氨基}丙酰基)氨基]-1H-咪唑-1-鎓ESI-MS[M+H]+:335(计算值:335)I-97   乙酸2-[(3-{[1-(3-羧基丙基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-
   基]氨基}丙酰基)氨基]-1H-咪唑-1-鎓ESI-MS[M+H]+:349(计算值:349)I-98   乙酸2-[5-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
   5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)噻吩-2-基]-3H-
   苯并咪唑-1-鎓ESI-MS[M+H]+:559(计算值:559)I-99   乙酸2-[5-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-甲基
   -2-氧代-1,2-二氢嘧啶-4-基]-氨基}甲基)噻吩-2-基]-3H-苯并
   咪唑-1-鎓ESI-MS[M+H]+:573(计算值:573)I-100  三氟乙酸2-[4-({[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
   基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}甲基)苯胺基]-
   1H-苯并咪唑-1-鎓ESI-MS[M+H]+:568(计算值:568)I-101  三氟乙酸2-[4-({[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]-氨基}甲基)苯胺基]-1H-苯并
   咪唑-1-鎓ESI-MS[M+H]+:582(计算值:582)I-102  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}甲基)氨基]-
   1,4,5,6-四氢-嘧啶-1-鎓ESI-MS[M+H]+:540(计算值:540)I-103  三氟乙酸N-{1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
   基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}吡啶-2-铵ESI-MS[M+H]+:507(计算值:507)I-104  乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
   5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-1H-苯
   并咪唑-1-鎓ESI-MS[M+H]+:534(计算值:534)I-105  乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
   5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-5,6-二
   甲基-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:562(计算值:562)I-106  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-1H-苯并
   咪唑-1-鎓ESI-MS[M+H]+:548(计算值:548)I-107  三氟乙酸2-[(3-{[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙酰基)氨基]-5,6-二甲
   基-1H-苯并咪唑-1-鎓ESI-MS[M+H]+:576(计算值:576)I-108  三氟乙酸2-[(3-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
   基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}丙基)氨基]吡啶
   鎓ESI-MS[M+H]+:481(计算值:481)I-109  乙酸2-[4-(2-{[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙
   基)-5-甲基-2-氧代-1,2-二氢嘧啶-4-基]氨基}乙基)苯基]-1H-
   苯并咪唑-1-鎓ESI-MS[M+H]+:567(计算值:567)I-110  乙酸2-[({1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
   5-甲基-2-氧代-1,2-二氢嘧啶-4-基]哌啶-4-基}羰基)氨基]吡啶
   鎓ESI-MS[M+H]+:535(计算值:535)I-111  乙酸2-[({1-[1-((2S)-2-{[(苄氧基)羰基]氨基}-2-羧基乙基)-
   5-甲基-2-氧代-1,2-二氢嘧啶-4-基]哌啶-4-基}羰基)氨基]-3H-
   苯并咪唑-1-鎓ESI-MS[M+H]+:574(计算值:574)I-112  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)-5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}羰基)氨基]吡啶
   鎓ESI-MS[M+H]+:549(计算值:549)I-113  三氟乙酸2-[({1-[1-(2-{[(苄氧基)羰基]氨基}-3-羧基丙基)5-
   甲基-2-氧代-1,2-二氢嘧啶-4-基]-哌啶-4-基}羰基)氨基]吡啶
   鎓ESI-MS[M+H]+:588(计算值:588)II生物学实施例实施例1整合素αvβ3测定
用一种实验系统,进行整合素αvβ3配体的鉴定和评价。此系统基于天然整合素αvβ3配体玻连蛋白和实验物质对固相结合的整合素αvβ3的结合之间的竞争。步骤:-用pH为9.2的含有250ng/ml整合素αvβ3的0.05M NaHCO3涂覆微量滴定板;0.1ml/孔;-用1%奶粉/测定缓冲液饱和;0.3ml/孔;0.5h/室温-用0.05%吐温20/测定缓冲液洗涤三次-含有实验物质的0.1%奶粉/测定缓冲液,50μl/孔+含有0μg/ml或2μg/ml人玻连蛋白(Boehringer Ingelheim T007)的0.1%奶粉/测定缓冲液,50μl/孔;1h/室温-用0.05%吐温20/测定缓冲液洗涤三次-含有与过氧化物酶偶合的1μg/ml人玻连蛋白抗体(Kordia SAVN-APHRP)的0.1%奶粉/测定缓冲液,0.1ml/孔;1h/室温-用0.05%吐温20/测定缓冲液洗涤三次-0.1ml/孔过氧化物酶底物-用0.1ml/孔2M H2SO4终止反应-测定在450nm的吸收整合素αvβ3:用Nonidet增溶人胎盘,并对整合素αvβ3在GRGDSPK基质上进行亲和纯化(用EDTA洗脱)。用阴离子交换层析去除由整合素αIIbβ3和人血清白蛋白、以及洗涤剂和EDTA所致的污染。
测定缓冲液:50mM Tris pH 7.5;100mM NaCl;1mM CaCl2;1mM MgCl2;10μM MnCl2
过氧化物酶底物:将0.1ml的TMB溶液(42mM TMB在DMSO中)与10ml底物缓冲液(0.1M乙酸钠pH4.9)混合,并然后加入14.7μl的3%H2O2
在测定中使用各种稀释的实验物质,确定IC50值(50%配体被置换时的配体的浓度)。在此方法中,来自于实施例I-40、I-45、I-54、I-61、I-63、I-64、I-72和I-49的化合物显示了最好的结果。实施例2整合素αIIbβ3测定
测定基于天然整合素αIIbβ3配体血纤蛋白原和实验物质对整合素αIIbβ3的结合之间的竞争。
步骤:-用pH为9.2的含有10μg/ml血纤蛋白原(Calbiochem 341578)的0.05MNaHCO3涂覆微量滴定板;0.1ml/孔;-用1%BSA/PBS饱和;0.3ml/孔;30分钟/室温-用0.05%吐温20/PBS洗涤三次-含有实验物质的0.1%BSA/PBS;50μl/孔+含有200μg/ml整合素αIIbβ3(Kordia)的0.1%BSA/PBS;50μl/孔;2至4h/室温-如上所述洗涤三次-生物素化的抗整合素αIIbβ3抗体(Dianova CBL 130B);1∶1000含于0.1%BSA/PBS中;0.1ml/孔;2至4h/室温-如上所述洗涤三次-链霉抗生物素蛋白-过氧化物酶复合物(B.M.1089153),1∶10,000含于0.1%BSA/PBS中;0.1ml/孔;30分钟/室温-如上所述洗涤三次-0.1ml/孔过氧化物酶底物-用0.1ml/孔2M H2SO4终止反应-测定在450nm的吸收
过氧化物酶底物:将0.1ml的TMB溶液(42mM TMB在DMSO中)与10ml底物缓冲液(0.1M乙酸钠pH 4.9)混合,然后加入14.7μl的3% H2O2
在测定中使用各种稀释的实验物质,确定IC50值(50%配体被置换时的拮抗剂的浓度)。通过比较在整合素αvβ3和整合素αIIbβ3测定中的IC50值,确定物质的选择性。实施例3CAM测定
为了测定整合素αvβ3拮抗剂的体内活性,通常采用CAM(绒膜尿囊膜)测定。它基于肿瘤组织的血管生成和新血管生成的抑制作用(Am.J.Pathol.1975,79,597-618;Cancer Res.1980,40,2300-2309;Nature1987,329,630)。操作与现有技术相似。鸡胚胎血管和移植的肿瘤组织的生长可很容易被跟踪和评价。实施例4兔眼测定
与实施例3相似,在该体内模型中,跟踪和评价在整合素αvβ3拮抗剂存在下,血管生成和新血管生成的抑制。此模型是被普遍承认的,它是基于从边缘开始进入兔眼角膜的血管的生长(Proc.Natl.Acad.Sci.USA.1994,91,4082-4085;Science 1976,193,70-72)。操作与现有技术相似。

Claims (33)

1.一种通式I的化合物:
               B-G-L                  I
其中B、G和L具有下列含义:
L是化学式IL的结构单元
                -U-T                   IL
其中
T是COOH基或者可水解成COOH的基团,并且
-U-是
-(CRL 1RL 2)a-(VL)b-(CRL 3RL 4)c-(WL)d-(CRL 5RL 6)e-(XL)f-(CRL 7RL 8)g-
其中
a,c,e,g分别是0,1,2,或3,
b,d,f分别是0或1,
RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7,RL 8分别是氢原子,卤素,羟基,支链或直链的、可以被取代或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基或者C1-C6-亚烷基-C3-C7-环烷基,-(CH2)w-(YL)y-RL 9基,可以被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基或者,在每种相互独立的情况中,两个基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8一起是3-至7-元、被取代的或不被取代的、饱和或不饱和的碳环或杂环,它可含有选自O、N和S组中的至多三个杂原子,
w是0、1、2、3或4,
y是0或1
YL是  -CO-,-CO-N(RY 1)-,-N(RY 1)-CO-,-N(RY 1)-CO-N(RY 1*)-,
      -N(RY 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RY 1)-,-SO2-O-,
      -CO-O-,-O-CO-,-O-CO-N(Ry 1)-,-N(RY 1)-或
      -N(RY 1)-SO2-,
RY 1,RY 1*
分别是氢,支链或直链的、被取代或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,芳基,芳烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-或SO2-亚烷基-芳基,
RL 9是氢,或者羟基,CN,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基,被取代或不被取代的C3-C7-环烷基-,芳基-,杂芳基或芳烷基,不被取代或被C1-C4-烷基或芳基取代的C2-C6-炔基或C2-C6-烯基,被取代或不被取代的C6-C12-二环烷基,C1-C6-亚烷基-C6-C12-双环烷基-,C7-C20-三环烷基-,或C1-C6-亚烷基-C7-C20-三环烷基,或3-至8-元、饱和或不饱和杂环并且该杂环由至多3个相同或不同基团取代并含有至多三个不同或相同的选自O、N、S的杂原子,其中两个基团可能一起形成稠合的,饱和的、不饱和的或芳香碳环或杂环,该杂环可含有至多3个不同或相同的选自O、N、S的杂原子,并且该环可能被取代或不被取代,或者另一被取代或不被取代的、饱和的、不饱和的或芳香环可稠合到该环上,或者RL 9基与RY 1或RY 1*形成饱和或不饱和的C3-C7-杂环,它还可以含有至多两个另外的选自O、S或N的杂原子,
WL是被取代的或不被取代的4-至11-元单环或多环脂族烃或芳香烃,它可含有至多6个双键和至多6个选自于N、O、S中的杂原子,
VL,XL
分别是                    -CO-,-CO-NRL 10-,-NRL 10-CO-,
-S-,-SO-,-SO2-,-SO2-NRL 10-,-NRL 10-SO2-,-CS-,
-CS-NRL 10-,-NRL 10-CS-,-CS-O-,-O-CS-,-CO-O-,
-O-CO-,-O-,亚乙炔基,-CHRL 11-O-CHRL 12-,
-C(=CRL 11RL 12)-,-CRL 11=CRL 12-,-CRL 11(ORL 13)-CHRL 12-,
-CHRL 11-CRL 12(ORL 13)-,-CH(NRL 14-SO2-RL 15)-,
-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,
CH(NRL 14-CO-NRL 14′RL 15)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-
或CH(CO-NRL 14RL 15)-,
RL 10是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基-,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-OC1-C6-烷基-,SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,芳烷基-,CO-芳基-,SO2-芳基-,杂芳基-,CO-杂芳基-,杂芳基烷基-或SO2-亚烷基-芳基,或者RL 10和选自于RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8中的一个基团一起是可含有至多5个相同或不同的O、N或S杂原子的被取代的或不被取代的4-至8-元杂环,
RL 11,RL 12
分别是氢,羟基,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C4-烷氧基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或者被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 13是氢、支链或直链、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 14,RL 14’
分别是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧烷基-,C2-C6-烯基,C3-C12-炔基,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,C1-C6-亚烷基-C3-C7-环烷基,或SO2-C1-C6-烷基被取代的或不被取代的C3-C7-环烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-,杂芳基烷基-,芳烷基或SO2-亚烷基芳基,
RL 15是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基-,C1-C6-亚烷基-C3-C7-环烷基,C6-C12-双环烷基-,C1-C6-亚烷基-C6-C12-双环烷基-,-C7-C20-三环烷基-或C1-C6-亚烷基-C7-C20-三环烷基,由至多3个相同或不同基团取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基烷基或3-至8-元、饱和、不饱和或芳香杂环基,该杂环可含有至多三个不同或相同的O、N、S的杂原子,其中两个基团一起可能是稠合的、饱和、不饱和或芳香碳环或可含有至多3个不同或相同的O、N、S杂原子的杂环,而且该环可能被取代或不被取代,或者另一个被取代的或不被取代的饱和、不饱和或芳香环可稠合到该环上,或者RL 15基与RL 14或RL 14*形成饱和或不饱和的任选含有至多两个另外的选自O、S或N中的杂原子的C3-C7-杂环,和
RL 16是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基,
G是具有化学式IG的结构单元
Figure A0080755400051
其中,结构单元G可在两个取向构建入,和
ZG是氧、硫或NRG 3
RG 1,RG 2
分别是氢,CN,NO2,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基或C2-C6-炔基,支链或直链、被取代的或不被取代的C1-C4-亚烷基-ORG 4,C1-C4-亚烷基-CO-ORG 4,C1-C4-亚烷基-CO-RG 4,C1-C4-亚烷基-SO2-NRG 5RG 6,C1-C4-亚烷基-CO-NRG 5RG 6,C1-C4-亚烷基-NRG 5RG 6或C1-C4-亚烷基-SRG 4,被取代的或不被取代的C3-C7-环烷基,C1-C4-亚烷基-C3-C7-环烷基,C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,被取代的或不被取代的芳基,芳烷基,杂芳基或杂芳烷基,-S-RG 4,-O-RG 4,-SO-RG 4,-SO2-RG 4,-CO-ORG4,-O-CO-RG 4,-O-CO-NRG 5RG 6,-SO2-NRG 5RG 6,-CO-NRG 5RG 6,-NRG 5RG 6,CO-RG 4,或RG 1和RG 2一起是被取代的或不被取代的、饱和的、不饱和的或芳香的3-至9-元碳环、多碳环、可含有至多4个选自O、N、S的杂原子的杂环或杂多环。
RG 3是氢,羟基,CN,支链或直链的、被取代的或不被取代的C1-C6-烷基或C1-C4-烷氧基或被取代的或不被取代的C3-C7-环烷基-,-O-C3-C7-环烷基,芳基-,-O-芳基,芳烷基或-O-亚烷基-芳基,
RG 4是氢,支链或直链被取代的或不被取代的C1-C8-烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基-,单-和双-烷基氨基亚烷基-或酰基氨基亚烷基或被取代的或不被取代的芳基,杂环烷基-,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基-,C1-C4-亚烷基-杂环烯基或杂芳基烷基,
RG 5,RG 6
分别是氢,支链或直链被取代的或不被取代的C1-C8烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基,单-和双烷基氨基亚烷基或酰基氨基亚烷基,被取代的或不被取代的芳基,杂环烷基,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基,C1-C4-亚烷基-杂环烯基-或杂芳烷基,或-SO2-RG 4,-CO-ORG 4,-CO-NRG 4RG 4*或-CO-RG 4,和
RG 4*是不同于RG 4的RG 4基,
B是含有至少一个原子的结构单元,这个原子在生理条件下作为氢受体可形成氢键,其中至少一个氢受体原子沿结构单元骨架沿最短的可能途径与结构单元G之间具有4至13原子键的间隔,
和生理学上可接受的盐、前体药物和对映体纯的或非对映体纯的和互变异构的形式。
2.按照权利要求1所述的化合物,其中结构单元B是具有通式IB的结构单元:
                      A-E-                 IB其中A和E具有下列含义:A是选自于下列组的结构单元:
可含有至多4个选自O、N或S杂原子的4-至8-元单环饱和的、不饱和的或芳香烃,在各种情况下,可能存在的环氮或碳可能分别被取代,条件是结构单元A中存在至少一个选自O、N或S的杂原子,或者
可含有至多6个选自O、N或S杂原子的9-至14-元多环饱和的、不饱和的或芳香烃,在各种情况下,可能存在的环氮或碳可能分别被取代,条件是结构单元A中存在至少一个选自O、N或S的杂原子,
基团:其中
ZA 1是氧、硫或被取代的或不被取代的氮,并且
ZA 2是被取代的或不被取代的氮、氧或硫,或者基团:
Figure A0080755400072
其中
RA 18、RA 19分别是氢、支链或直链的、被取代的或不被取代的C1-C8-烷基、C2-C6-烯基、C2-C6-炔基或C1-C5-亚烷基-C1-C4-烷氧基、单或双烷基氨基亚烷基或酰基氨基亚烷基或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳烷基、C1-C4-亚烷基-杂环烷基、C1-C4-亚烷基-杂环烯基或杂芳烷基或者-SO2-RG 4、-CO-O-RG 4、-CO-NRG 4RG 4*或-CO-RG 4,并且E是将结构单元A与结构单元G共价连接的间隔结构单元,其中沿结构单元骨架E沿可能的最短途径的原子键数是3到12。
3.按照权利要求1或2所述的化合物,其中结构单元A是选自通式IA 1到IA 19的结构单元的组:
Figure A0080755400081
其中:
m,p,q相互独立地是1,2或3,
RA 1、RA 2分别是氢、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或CO-C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、杂芳基烷基或C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、CO-NRA 15RA 16或SO2NRA 15RA 16或者RA 1和RA 2一起是稠合的、被取代的或不被取代的、5-或6-元、不饱和的或芳香的碳环或杂环,其中该杂环可以含有至多3个选自O、N或S的杂原子,
RA 13、RA 13*分别是氢、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16或SO2-NRA 15RA 16或CO-NRA 15RA 16
其中RA 14是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、亚烷基-C1-C4-烷氧基、C2-C6-烯基、C2-C6-炔基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、杂芳基或杂芳烷基,
RA 15、RA 16分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、CO-C1-C6-烷基、SO2-C1-C6-烷基、COO-C1-C6-烷基、CO-NH-C1-C6-烷基、芳烷基、COO-亚烷基-芳基、SO2-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-NH-亚烷基-杂芳基或杂芳烷基或者被取代的或不被取代的C3-C7-环烷基、芳基、CO-芳基、CO-NH-芳基、SO2-芳基、杂芳基、CO-NH-杂芳基或CO-杂芳基,
RA 3、RA 4分别是氢、-(CH2)n-(XA)j-RA 12或者两个基团一起是3-到8-元、饱和的或不饱和的或芳香的N杂环,该杂环还可含有两个其他相同或不同的杂原子O、N或S,该环可能被取代或不被取代,或者另外一个被取代的或不被取代的饱和的或不饱和的或芳香环可能与该环稠合,
其中
n是0,1,2或3,
j是0或1,
XA是   -CO-,-CO-N(Rx 1)-,-N(Rx 1)-CO-,-N(Rx 1)-CO-N(Rx 1*)-,
       -N(Rx 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(Rx 1)-,-SO2-O-,
       -CO-O-,-O-CO-,-O-CO-N(Rx 1)-,-N(Rx 1)-或
       -N(Rx 1)-SO2-,
RA 12是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、被C1-C4-烷基-或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基或者被至多3个相同或不同的基团取代的、3-到6-元、饱和的或不饱和的杂环,该杂环可含有至多3个相同或不同的杂原子O、N、S,C3-C7-环烷基、芳基、杂芳基,其中两个基团可能一起形成稠合的、饱和的或不饱和的或芳香的碳环或杂环,其中杂环可以含有至多3个选自O、N或S的杂原子,并且该环可能被取代或不被取代,或者另外一个被取代的或不被取代的饱和的或不饱和的或芳香环可能与该环稠合,或者RA 12能够与RX 1或RX 1*一起形成饱和的或不饱和的C3-C7-杂环,它任选含有至多2个另外的选自O、S或N的杂原子,
RX 1、RX 1*分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、杂芳基、CO-杂芳基或SO2-亚烷基-芳基,
RA 5是支链或直链的、被取代的或不被取代的C1-C6-烷基、芳烷基、C3-C7-环烷基或C1-C4-亚烷基-C3-C7-环烷基或者被取代的或不被取代的芳基、杂芳基、杂环烷基或杂环烯基,
RA 6、RA 6*是氢、支链或直链的、被取代的或不被取代的C1-C4-烷基、-CO-O-C1-C4-烷基、芳烷基、-CO-O-亚烷基-芳基、-CO-O-烯丙基、-CO-C1-C4-烷基、-CO-亚烷基-芳基、C3-C7-环烷基或-CO-烯丙基或者在结构单元IA 7中的两个基团RA 6和RA 6*一起形成被取代的或不被取代的、饱和的或不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多两个另外的不同或相同的杂原子O、N、S,
RA 7是氢、-OH、-CN、-CONH2、支链或直链的、被取代的或不被取代的C1-C4-烷基、C1-C4-烷氧基、C3-C7-环烷基或-O-CO-C1-C4-烷基或被取代的或不被取代的芳烷基、-O-亚烷基-芳基、-O-CO-芳基、-O-CO-亚烷基-芳基或-O-CO-烯丙基,或RA 6和RA 7两个基团一起形成被取代的或不被取代的、不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多两个另外的不同或相同的杂原子O、N、S,
RA 8是氢、支链或直链的、被取代的或不被取代的C1-C4-烷基、CO-C1-C4-烷基、SO2-C1-C4-烷基或CO-O-C1-C4-烷基或被取代的或不被取代的芳基、CO-芳基、SO2-芳基、CO-O-芳基、CO-亚烷基-芳基、SO2-亚烷基-芳基、CO-O-亚烷基-芳基或亚烷基-芳基,
RA 9、RA 10分别是氢、-CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16,或者在结构单元IA 14中的两个基团RA 9和RA 10一起形成5-到7-元、饱和的或不饱和的或芳香碳环或杂环,该杂环可以含有至多三个不同或相同的杂原子O、N、S并且被至多三个相同或不同的基团取代或不被取代,
RA 11是氢、-CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基或被取代的或不被取代的芳基、芳烷基、杂芳基、C3-C7-环烷基或-CO-O-RA 14、O-RA 14、S-RA 14、NRA 15RA 16、SO2-NRA 15RA 16或CO-NRA 15RA 16
RA 17是氢或者在结构单元IA 16中的两个基团RA 9和RA 17一起形成5-到7-元、饱和的或不饱和的或芳香杂环,除了环氮外,该杂环还可以含有至多三个不同或相同的杂原子O、N、S并且被至多三个相同或不同的基团取代或不被取代,
RA 18、RA 19分别是氢、支链或直链的、被取代的或不被取代的C1-C8-烷基、C2-C6-烯基、C2-C6-炔基、C1-C5-亚烷基-C1-C4-烷氧基、单-和双烷基氨基亚烷基或酰基氨基亚烷基、或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳烷基、C1-C4-亚烷基-杂环烷基、C1-C4-亚烷基-杂环烯基、或杂芳烷基、或者-SO2-RG 4、-CO-O-RG 4、-CO-NRG 4RG 4*或-CO-RG 4
Z1、Z2、Z3、Z4分别是氮、C-H、C-卤素或支链的或直链的、被取代的或不被取代的C-C1-C4-烷基或C-C1-C4-烷氧基,
Z5是NRA 8、氧或硫。
4.按照权利要求1到3中任何一个所述的化合物,其中间隔的结构单元E是具有通式IE的结构单元:
              -(NRE 1)i-E1-(UE)h-           IE
其中:
UE是氧、硫或NRE 2
h是0或1,
i是0或1,
RE 1,RE 2分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C6-烷氧基烷基、C2-C6-烯基、C2-C12-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基、CO-NH-C1-C6-烷氧基烷基,CO-NH-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的杂芳基、芳基烷基、C3-C7-环烷基、CO-O-亚烷基-芳基、CO-NH-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、CO-NH-芳基、SO2-芳基、CO-杂芳基、SO2-亚烷基-芳基、SO2-杂芳基或SO2-亚烷基-杂芳基,
E1是具有结构式IE1的结构单元:
-(CRE 3RE 4)k1-(LE)k2-(CRE 5RE 6)k3-(QE)k4-(CRE 7RE 8)k5-(TE)k6-(CRE 9RE 10)k7-
                              IE1其中k2、k4、k6是0或1,k1、k3、k5、k7是0,1或2,RE 3、RE 4、RE 5、RE 6、RE 7、RE 8、RE 9、RE 10分别是氢、卤素、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基、-(CH2)X-(YE)ZRE 11、被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,或在每种情况下相互独立地,两个基团RE 3和RE 4或RE 5和RE 6或RE 7和RE 8或RE 9和RE D一起是3-7元被取代的或不被取代的饱和的或不饱和的碳环或杂环,其中杂环可以含有至多3个选自O、N、S中的杂原子,x是0、1、2、3或4,z是0或1,YE
-CO-,-CO-N(Ry 2)-,-N(Ry 2)-CO-  -N(Ry 2)-CO-N(Ry 2*)-,
-N(Ry 2)-CO-O-,-O-,-S-,-SO2-,-SO2-N(Ry 2)-,-SO2-O-,
-CO-O-,-O-CO-,-O-CO-N(Ry 2)-,-N(Ry 2)-或-N(Ry 2)-SO2-,Ry 2、Ry 2*分别是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C8-炔基、CO-C1-C6-烷基、CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的杂芳基、杂芳基烷基、芳烷基、C3-C7-环烷基、CO-O-亚烷基-芳基、CO-亚烷基-芳基、CO-芳基、SO2-芳基、CO-杂芳基或SO2-亚烷基-芳基,RE 11是氢、羟基、CN、卤素、支链或直链的、被取代的或不被取代的C1-C6-烷基、被取代的或不被取代的C3-C7-环烷基、芳基、杂芳基或芳基烷基、被C1-C4-烷基或芳基取代的或不被取代的C2-C6-炔基或C2-C6-烯基、被取代的或不被取代的C6-C12-双环烷基、C1-C6-亚烷基-C6-C12-双环烷基、C7-C20-三环烷基或C1-C6-亚烷基-C7-C20-三环烷基,或3-到8-元饱和的或不饱和的杂环,该杂环被至多三个相同的或不同的基团取代并且可以含有至多三个不同的或相同的O、N、S杂原子,其中两个基团一起可能会形成稠合的、饱和的、不饱和的或芳香的碳环或杂环,其中杂环可含有至多三个相同的或不同的O、N、S杂原子,并且该环可能被取代或不被取代,或者另外的、被取代的或不被取代的、饱和的、或不饱和的或芳香环可能会与该环稠合,或者RE 11与Ry 2、或RY 2*一起形成饱和的或不饱和的C3-C7-杂环,该杂环可以含有至多两个另外选自O、S、N的杂原子,LE、TE分别是CO、CO-NRE 12、NRE 12-CO、硫、SO、SO2、SO2-NRE 12、NRE 12-SO2、CS、CS-NRE 12、NRE 12-CS、CS-O、O-CS、CO-O、O-CO、氧、亚乙炔基、CRE 13-O-CRE 14、C(=CRE 13 RE 14)、CRE 13=CRE 14、-CRE 13(ORE 15)-CHRE 14-、-CHRE 13-CRE 14(ORE 15)-,RE 12是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C8-炔基、被取代的或不被取代的C3-C7-环烷基、杂芳基、芳基烷基或杂芳基烷基或CO-RE 16、COORE 16或SO2-RE 16,RE 13、RE 14分别是氢、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C1-C4-烷氧基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,RE 15是氢、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基、芳基、芳基烷基、杂芳基或杂芳基烷基,RE 16是氢、羟基、支链或直链的、被取代的或不被取代的C1-C6-烷基、C2-C6-烯基、C2-C6-炔基或C1-C5-亚烷基-C1-C4-烷氧基或被取代的或不被取代的芳基、杂环烷基、杂环烯基、杂芳基、C3-C7-环烷基、C1-C4-亚烷基-C3-C7-环烷基、芳基烷基、C1-C4-亚烷基-C3-C7-杂环烷基、C1-C4-亚烷基-C3-C7-杂环烯基或杂芳基烷基并且QE是被取代的或不被取代的4-到11-元单-或多环脂族或芳香烃,它可以含有至多6个双键和至多6个相同或不同的选自于N、O、S杂原子,其中环碳或环氮可能被取代。
5.通式IGL结构单元在制备能够与整合素受体结合的化合物方面的用途,         -G-L                     IGL
其中G和L具有下列含义:
L是化学式IL的结构单元
                 -U-T               IL
其中
T是COOH基或者可水解成COOH的基团,并且
-U-是
-(CRL 1RL 2)a-(VL)b-(CRL 3RL 4)c-(WL)d-(CRL 5RL 6)e-(XL)f-(CRL 7RL 8)g-
其中
a,c,e,g相互独立地是0,1,2,或3,
b,d,f相互独立地是0或1,
RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7,RL 8分别是氢原子,卤素,羟基,支链或直链的、可以被取代或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基或者C1-C6-亚烷基-C3-C7-环烷基,-(CH2)w-(YL)y-RL 9基,可以被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基或者,在每种相互独立的情况中,两个基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8一起是3-至7-元、被取代的或不被取代的、饱和或不饱和的碳环或杂环,它可含有选自O、N和S组中的至多三个杂原子,
w是0、1、2、3或4,
y是0或1
YL
-CO-,-CO-N(RY 1)-,-N(RY 1)-CO-,-N(RY 1)-CO-N(RY 1*)-,
-N(RY 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RY 1)-,-SO2-O-,
-CO-O-,-O-CO-,-O-CO-N(Ry 1)-,-N(RY 1)-或
-N(RY 1)-SO2-,
RY 1,RY 1*
分别是氢,支链或直链的、被取代或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,芳基,芳烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-或SO2-亚烷基-芳基,
RL 9是氢,或者羟基,CN,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基,被取代或不被取代的C3-C7-环烷基-,芳基-,杂芳基或芳烷基,不被取代或被C1-C4-烷基或芳基取代的C2-C6-炔基或C2-C6-烯基,被取代或不被取代的C6-C12-二环烷基,C1-C6-亚烷基-C6-C12-双环烷基-,C7-C20-三环烷基-,或C1-C6-亚烷基-C7-C20-三环烷基,或3-至8-元、饱和或不饱和杂环杂环并且该杂环由至多3个相同或不同基团取代并可含有至多三个不同或相同的选自O、N、S的杂原子,其中两个基团可能一起形成稠合的、饱和的、不饱和的或芳香碳环或杂环,该杂环可含有至多3个不同或相同的选自O、N、S的杂原子,并且该环可能被取代或不被取代,或者另一被取代或不被取代的、饱和的、不饱和的或芳香环可稠合到该环上,或者RL 9基与RY 1或RY 1*形成饱和或不饱和的C3-C7-杂环,该杂环还可以含有至多两个另外的选自O、S或N的杂原子,
WL是被取代的或不被取代的4-至11-元单环或多环脂族烃或芳香烃,它可含有至多6个双键和至多6个选自于N、O、S中的杂原子,
VL,XL
分别是                     -CO-,-CO-NRL 10、-NRL 10-CO-,
-S-,-SO-,-SO2-,-SO2-NRL 10-,-NRL 10-SO2-,-CS-,
-CS-NRL 10-,-NRL 10-CS-,-CS-O-,-O-CS-,-CO-O-,
-O-CO-,-O-,Ethinylen,-CHRL 11-O-CHRL 12-,
-C(=CRL 11RL 12)-,-CRL 11=CRL 12-,-CRL 11(ORL 13)-CHRL 12-,
-CHRL 11-CRL 12(ORL 13)-,-CH(NRL 14-SO2-RL 15)-,
-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,
CH(NRL 14-CO-NRL 14′RL 15)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-
或CH(CO-NRL 14RL 15)-
RL 10是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基-,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-OC1-C6-烷基-,SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基,CO-O-亚烷基-芳基-,CO-亚烷基-芳基,芳烷基-,CO-芳基-,SO2-芳基-,杂芳基-,CO-杂芳基-,杂芳基烷基-或SO2-亚烷基-芳基,或者RL 10和选自于RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8中的一个基团一起可以是含有至多5个相同或不同的O、N或S杂原子的被取代的或不被取代的4-至8-元杂环,
RL 11,RL 12
分别是氢,羟基,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C4-烷氧基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或者被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 13是氢、支链或直链、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 14,RL 14’
分别是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧烷基-,C2-C6-烯基,C3-C12-炔基,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,C1-C6-亚烷基-C3-C7-环烷基,或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-,杂芳基烷基-,芳烷基或SO2-亚烷基芳基,
RL 16是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基-,C1-C6-亚烷基-C3-C7-环烷基,C6-C12-双环烷基-,C1-C6-亚烷基-C6-C12-双环烷基-,-C7-C20-三环烷基-或C1-C6-亚烷基-C7-C20-三环烷基,由至多3个相同或不同基团取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基烷基或3-至8-元、饱和、不饱和或芳香杂环基,该杂环可含有至多三个不同或相同的O、N、S的杂原子,其中两个基团一起可能是稠合的、饱和、不饱和或芳香碳环或杂环,该杂环可含有至多3个不同或相同的O、N、S杂原子,而且该环可能被取代或不被取代,或者另一个被取代的或不被取代的饱和、不饱和或芳香环可稠合到该环上,或者RL 15基与RL 14或RL 14*形成饱和或不饱和的任选含有至多两个另外的选自O、S或N中的杂原子的C3-C7-杂环,和
RL 16是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基,
G是具有化学式IG的结构单元
Figure A0080755400171
其中,结构单元G可在两个取向构建入,和
ZG是氧、硫或NRG 3
RG 1,RG 2
分别是氢,CN,NO2,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基或C2-C6-炔基,支链或直链、被取代的或不被取代的C1-C4-亚烷基-ORG 4,C1-C4-亚烷基-CO-ORG 4,C1-C4-亚烷基-CO-RG 4,C1-C4-亚烷基-SO2-NRG 5RG 6,C1-C4-亚烷基-CO-NRG 5RG 6,C1-C4-亚烷基-NRG 5RG 6或C1-C4-亚烷基-SRG 4,被取代的或不被取代的C3-C7-环烷基,C1-C4-亚烷基-C3-C7-环烷基,C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,被取代的或不被取代的芳基,芳烷基,杂芳基或杂芳烷基,-S-RG 4,-O-RG 4,-SO-RG 4,-SO2-RG 4,-CO-ORG 4,-O-CO-RG 4,-O-CO-NRG 5RG 6,-SO2-NRG 5RG 6,-CO-NRG 5RG 6,-NRG 5RG 6,CO-RG 4,或RG 1和RG 2一起是被取代的或不被取代的、饱和的、不饱和的或芳香的3-至9-元碳环、多碳环、含有至多4个选自O、N、S的杂原子的杂环或杂多环。
RG 3是氢,羟基,CN,支链或直链的、被取代的或不被取代的C1-C6-烷基或C1-C4-烷氧基或被取代的或不被取代的C3-C7-环烷基-,-O-C3-C7-环烷基,芳基-,-O-芳基,芳烷基或-O-亚烷基-芳基。
RG 4是氢,支链或直链被取代的或不被取代的C1-C8-烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基-,单-和双-烷基氨基亚烷基-或酰基氨基亚烷基或被取代的或不被取代的芳基,杂环烷基-,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基-,C1-C4-亚烷基-杂环烯基或杂芳基烷基,
RG 5,RG 6
分别是氢,支链或直链被取代的或不被取代的C1-C8烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基,单-和双烷基氨基亚烷基或酰基氨基亚烷基,被取代的或不被取代的芳基,杂环烷基,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基,C1-C4-亚烷基-杂环烯基-或杂芳烷基,或-SO2-RG 4,-CO-ORG 4,-CO-NRG 4RG 4*或-CO-RG 4,和
RG 4*是不同于RG 4的RG 4基。
6.一种含有通式IGL结构单元的药物:
                   -G-L                IGL其中G和L具有下列含义:
L是化学式IL的结构单元
                   -U-T                 IL
其中
T是COOH基或者可水解成COOH的基团,并且
-U-是
-(CRL 1RL 2)a-(VL)b-(CRL 3RL 4)c-(WL)d-(CRL 5RL 6)e-(XL)f-(CRL 7RL 8)g-
其中
a,c,e,g相互独立地是0,1,2,或3,
b,d,f相互独立地是0或1,
RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7,RL 8分别是氢原子,卤素,羟基,支链或直链的、可以被取代或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基或者C1-C6-亚烷基-C3-C7-环烷基,-(CH2)w-(YL)y-RL 9基,可以被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基或者,在每种相互独立的情况中,两个基团RL 1和RL 2或RL 3和RL 4或RL 5和RL 6或RL 7和RL 8一起是3-至7-元、被取代的或不被取代的、饱和或不饱和的碳环或杂环,它可含有选自O、N和S组中的至多三个杂原子,
w是0、1、2、3或4,
y是0或1
YL
-CO-,-CO-N(RY 1)-,-N(RY 1)-CO-,-N(RY 1)-CO-N(RY 1*)-,
-N(RY 1)-CO-O-,-O-,-S-,-SO2-,-SO2-N(RY 1)-,-SO2-O-,
-CO-O-,-O-CO-,-O-CO-N(Ry 1)-,-N(RY 1)-或
-N(RY 1)-SO2-,
RY 1,RY 1*
分别是氢,支链或直链的、被取代或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,芳基,芳烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-或SO2-亚烷基-芳基,
RL 9是氢,或者羟基,CN,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基,被取代或不被取代的C3-C7-环烷基-,芳基-,杂芳基或芳烷基,不被取代或被C1-C4-烷基或芳基取代的C2-C6-炔基或C2-C6-烯基,被取代或不被取代的C6-C12-二环烷基,C1-C6-亚烷基-C6-C12-双环烷基-,C7-C20-三环烷基-,或C1-C6-亚烷基-C7-C20-三环烷基,或3-至8-元、饱和或不饱和杂环杂环并且该杂环由至多3个相同或不同基团取代并可含有至多三个不同或相同的选自O、N、S的杂原子,其中两个基团可能一起形成稠合的、饱和的、不饱和的或芳香碳环或杂环,该杂环可含有至多3个不同或相同的选自O、N、S的杂原子,并且该环可能被取代或不被取代,或者另一被取代或不被取代的、饱和的、不饱和的或芳香环可稠合到该环上,或者RL 9基与RY 1或RY 1*形成饱和或不饱和的C3-C7-杂环,该杂环还可以含有至多两个另外的选自O、S或N的杂原子,
WL是被取代的或不被取代的4-至11-元单环或多环脂族烃或芳香烃,它可含有至多6个双键和至多6个选自于N、O、S中的杂原子,
VL,XL
分别是
                        -CO-,-CO-NRL 10-,-NRL 10-CO-,
-S-,-SO-,-SO2-,-SO2-NRL 10-,-NRL 10-SO2-,-CS-,
-CS-NRL 10-,-NRL 10-CS-,-CS-O-,-O-CS-,-CO-O-,
-O-CO-,-O-,亚乙炔基,-CHRL 11-O-CHRL 12-,
-C(=CRL 11RL 12)-,-CRL 11=CRL 12-,-CRL 11(ORL 13)-CHRL 12-,
-CHRL 11-CRL 12(ORL 13)-,-CH(NRL 14-SO2-RL 15)-,
-CH(NRL 14-CO-RL 15)-,-CH(NRL 14-CO-ORL 16)-,
CH(NRL 14-CO-NRL 14′RL 15)-,-CH(CO-RL 15)-,-CH(CO-ORL 16)-
或CH(CO-NRL 14RL 15)-,RL 10是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧基烷基-,C2-C6-烯基-,C3-C12-炔基-,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基,CO-O-亚烷基-芳基-,CO-亚烷基-芳基,芳烷基-,CO-芳基-,SO2-芳基-,杂芳基-,CO-杂芳基-,杂芳基烷基-或SO2-亚烷基-芳基,或者RL 10和选自于RL 1,RL 2,RL 3,RL 4,RL 5,RL 6,RL 7或RL 8中的一个基团一起可以是含有至多5个相同或不同的O、N或S杂原子的被取代的或不被取代的4-至8-元杂环,
RL 11,RL 12
分别是氢,羟基,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C4-烷氧基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或者被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 13是氢、支链或直链、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基-,C2-C6-炔基-或亚烷基-环烷基或被取代的或不被取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基-或杂芳基烷基,
RL 14,RL 14’
分别是氢,支链或直链、被取代的或不被取代的C1-C6-烷基-,C1-C6-烷氧烷基-,C2-C6-烯基,C3-C12-炔基,CO-C1-C6-烷基-,CO-O-C1-C6-烷基-,C1-C6-亚烷基-C3-C7-环烷基,或SO2-C1-C6-烷基或被取代的或不被取代的C3-C7-环烷基-,CO-O-亚烷基-芳基-,CO-亚烷基-芳基-,芳基-,CO-芳基,SO2-芳基-,杂芳基,CO-杂芳基-,杂芳基烷基-,芳烷基或SO2-亚烷基芳基,
RL 15是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基-,C1-C6-亚烷基-C3-C7-环烷基,C6-C12-双环烷基-,C1-C6-亚烷基-C6-C12-双环烷基-,-C7-C20-三环烷基-或C1-C6-亚烷基-C7-C20-三环烷基,由至多3个相同或不同基团取代的C3-C7-环烷基-,芳基-,芳烷基-,杂芳基烷基或3-至8-元、饱和、不饱和或芳香杂环基,该杂环可含有至多三个不同或相同的O、N、S的杂原子,其中两个基团一起可能是稠合的、饱和、不饱和或芳香碳环或杂环,该杂环可含有至多3个不同或相同的O、N、S杂原子,而且该环可能被取代或不被取代,或者另一个被取代的或不被取代的饱和、不饱和或芳香环可稠合到该环上,或者RL 15基与RL 14或RL 14*形成饱和或不饱和的任选含有至多两个另外的选自O、S或N中的杂原子的C3-C7-杂环,和
RL 16是支链或直链、被取代的或不被取代的C1-C6-烷基-,烷氧基烷基或C1-C6-亚烷基-C3-C7-环烷基或被取代的或不被取代的C3-C7-环烷基,芳基,芳烷基,杂芳基或杂芳基烷基,
G是具有化学式IG的结构单元
Figure A0080755400221
其中,结构单元G可在两个取向构建入,和
ZG是氧、硫或NRG 3
RG 1,RG 2
分别是氢,CN,NO2,卤素,支链或直链的、被取代的或不被取代的C1-C6-烷基-,C2-C6-烯基或C2-C6-炔基,支链或直链、被取代的或不被取代的C1-C4-亚烷基-ORG 4,C1-C4-亚烷基-CO-ORG 4,C1-C4-亚烷基-CO-RG 4,C1-C4-亚烷基-SO2-NRG 5RG 6,C1-C4-亚烷基-CO-NRG 5RG 6,C1-C4-亚烷基-NRG 5RG 6或C1-C4-亚烷基-SRG 4,被取代的或不被取代的C3-C7-环烷基,C1-C4-亚烷基-C3-C7-环烷基,C1-C4-亚烷基-C3-C7-杂环烷基或C1-C4-亚烷基-C3-C7-杂环烯基,被取代的或不被取代的芳基,芳烷基,杂芳基或杂芳烷基,-S-RG 4,-O-RG 4,-SO-RG 4,-SO2-RG 4,-CO-ORG 4,-O-CO-RG 4,-O-CO-NRG 5RG 6,-SO2-NRG 5RG 6,-CO-NRG 5RG 6,-NRG 5RG 6,CO-RG 4,或RG 1和RG 2一起是被取代的或不被取代的、饱和的、不饱和的或芳香的3-至9-元碳环、多碳环、含有至多4个选自O、N、S的杂原子的杂环或杂多环。
RG 3是氢,羟基,CN,支链或直链的、被取代的或不被取代的C1-C6-烷基或C1-C4-烷氧基或被取代的或不被取代的C3-C7-环烷基-,-O-C3-C7-环烷基,芳基-,-O-芳基,芳烷基或-O-亚烷基-芳基。
RG 4是氢,支链或直链被取代的或不被取代的C1-C8-烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基-,单-和双-烷基氨基亚烷基-或酰基氨基亚烷基或被取代的或不被取代的芳基,杂环烷基-,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基-,C1-C4-亚烷基-杂环烯基或杂芳基烷基,
RG 5,RG 6
分别是氢,支链或直链被取代的或不被取代的C1-C8烷基,C2-C6-烯基,C2-C6-炔基,C1-C5-亚烷基-C1-C4-烷氧基,单-和双烷基氨基亚烷基或酰基氨基亚烷基,被取代的或不被取代的芳基,杂环烷基,杂环烯基,杂芳基,C3-C7-环烷基-,C1-C4-亚烷基-C3-C7-环烷基-,芳烷基-,C1-C4-亚烷基-杂环烷基,C1-C4-亚烷基-杂环烯基-或杂芳烷基,或-SO2-RG 4,-CO-ORG 4,-CO-NRG 4RG 4*或-CO-RG 4,和RG 4*是不同于RG 4的RG 4基。
7.一种含有至少一种权利要求1到4中任何一个所述的化合物以及常用药物赋型剂的药物制剂。
8.权利要求1到4中任何一个所述的化合物在制备治疗疾病的药物方面的用途。
9.权利要求1到4中任何一个所述的化合物作为整合素受体配体的用途。
10.按照权利要求9所述的权利要求1到4中任何一个所述的化合物的用途,作为αvβ3整合素受体的配体。
11.按照权利要求8所述的权利要求1到4中任何一个所述的化合物的用途,是制备治疗其中整合素及其天然配体之间相互作用增加或减少的疾病的药物方面的用途。
12.按照权利要求11所述的权利要求1到4中任何一个所述的化合物的用途,是治疗其中αvβ3整合素及其天然配体之间相互作用增加或减少的疾病。
13.按照权利要求12所述的权利要求1到4中任何一个所述的化合物的用途,是治疗动脉粥样硬化、类风湿性关节炎、血管损伤或斯滕特固定模移植后再狭窄、血管成形术、急性肾衰竭、与血管生成有关的微血管病、糖尿病型血管病、血小板介导的血管闭塞、动脉血栓、充血性心力衰竭、心肌梗死、中风、癌症、骨质疏松、高血压、牛皮癣或病毒、寄生虫或细菌疾病、炎症、伤口愈合、甲状膀腺机能亢进、佩吉特病、恶性高钙血症或转移性溶骨损伤。
14.一种含有至少一种权利要求1到4中任何一种所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
血小板粘附、活化或聚集抑制剂、
能够降低凝血酶活性或阻止凝血酶形成的抗凝剂、
血小板活化化合物的拮抗剂或选择蛋白拮抗剂。
15.权利要求14所述的药物制剂在制备治疗由血小板介导的血管闭塞或血栓形成的药物方面的用途。
16.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
血小板激活或凝聚抑制剂、
丝氨酸蛋白酶抑制剂、
减少纤维蛋白原的化合物、
选择蛋白拮抗剂、
ICAM-1或VCAM-1的拮抗剂、
白细胞粘附抑制剂、
血管壁血细胞外渗抑制剂、
调节纤维蛋白溶解的化合物、
补体因子的抑制剂、
内皮素受体拮抗剂、
酪氨酸激酶抑制剂、
抗氧化剂或者
白介素8拮抗剂。
17.权利要求16所述的药用制剂在制备治疗心肌梗死或中风的药物方面的用途。
18.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
内皮素拮抗剂、
ACE抑制剂、
血管紧张素受体拮抗剂、
内肽酶抑制剂、
β-阻滞剂、
钙通道拮抗剂、
磷酸二酯酶抑制剂或
caspase抑制剂。
19.权利要求18所述的药用制剂在制备治疗充血性心力衰竭的药物方面的用途。
20.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
凝血酶抑制剂、
Xa因子抑制剂、
导致凝血酶形成的凝血途径的抑制剂、
血小板粘附、激活或聚集的抑制剂、
内皮素拮抗剂、
氧化氮合成酶抑制剂、
CD44拮抗剂、
选择蛋白拮抗剂、
MCP-1拮抗剂、
增殖细胞中的信号转导抑制剂、
由EGF、PDGF、VEGF或bFGF介导的细胞反应拮抗剂或者
抗氧化剂。
21.权利要求20所述的药用制剂在制备治疗血管损伤或斯滕特固定模移植后再狭窄的药物方面的用途。
22.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
由EGF、PDGF、VEGF或bFGF介导的细胞反应拮抗剂、
肝素或低分子量肝素或其他GAGs、
MMPs的抑制剂、
选择蛋白拮抗剂、
内皮素拮抗剂、
ACE抑制剂、
血管紧张素受体拮抗剂、
糖基化抑制剂或者
AGE形成抑制剂或AGE阻滞剂和它们受体的拮抗剂。
23.权利要求22所述的药用制剂在制备治疗糖尿病型血管病的药物方面的用途。
24.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
降脂化合物、
选择蛋白拮抗剂、
ICAM-1或VCAM-1的拮抗剂、
肝素或低分子量肝素或其他GAGs、
MMPs的抑制剂、
内皮素拮抗剂、
载脂蛋白Al拮抗剂、
胆固醇拮抗剂、
HMG-CoA还原酶抑制剂、
ACAT抑制剂、
ACE抑制剂、
血管紧张素受体拮抗剂、
酪氨酸激酶抑制剂、
蛋白激酶C抑制剂、
钙通道拮抗剂、
LDL受体功能刺激剂、
抗氧化剂、
LCAT模拟物或者
自由基清除剂。
25.权利要求24所述的药用制剂在制备治疗动脉粥样硬化的药物方面的用途。
26.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
抑制细胞的或抗肿瘤化合物、
能够抑制增生的化合物或者
肝素或低分子量肝素或其他GAGs。
27.权利要求26所述的药用制剂在制备治疗癌症的药物方面的用途。
28.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
用于抗吸收治疗的化合物、
用于激素替代疗法的化合物、
重组人生长激素、
双膦酸酯、
用于降钙素治疗中的化合物、
降钙素刺激剂、
钙通道拮抗剂、
骨形成促进剂、
白介素-6拮抗剂或
Src酪氨酸激酶抑制剂。
29.权利要求28所述的药用制剂在制备治疗骨质疏松的药物方面的用途。
30.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
TNF拮抗剂、
VLA-4或VCAM-1的拮抗剂、
LFA-1、Mac-1或ICAMs的拮抗剂、
补体抑制剂、
免疫抑制剂、
白介素-1、-5或-8拮抗剂或
二氢叶酸还原酶抑制剂。
31.权利要求30所述的药用制剂在制备治疗类风湿性关节炎的药物方面的用途。
32.一种含有至少一种权利要求1到4中任何一个所述的化合物、任选的药物赋型剂和至少一种其他选自于下组的化合物的药物制剂:
胶原酶、
PDGF拮抗剂或
MMPs。
33.权利要求32所述的药用制剂在制备治疗伤口愈合的药物方面的用途。
CN00807554A 1999-04-13 2000-03-29 整合素受体配体 Pending CN1353706A (zh)

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