CN1313450C - 速激肽受体拮抗剂 - Google Patents

速激肽受体拮抗剂 Download PDF

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Publication number
CN1313450C
CN1313450C CNB03809360XA CN03809360A CN1313450C CN 1313450 C CN1313450 C CN 1313450C CN B03809360X A CNB03809360X A CN B03809360XA CN 03809360 A CN03809360 A CN 03809360A CN 1313450 C CN1313450 C CN 1313450C
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Prior art keywords
trifluoromethyl
phenyl
benzyl
alkyl
bis
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Expired - Fee Related
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English (en)
Chinese (zh)
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CN1649849A (zh
Inventor
A·K·阿梅加兹
K·M·加迪尼尔
E·J·赫姆布雷
J·E·洪
L·N·荣黑姆
M·A·罗伯逊
K·A·萨文
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Eli Lilly and Co
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Eli Lilly and Co
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    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Hematology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
CNB03809360XA 2002-04-26 2003-04-22 速激肽受体拮抗剂 Expired - Fee Related CN1313450C (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37612102P 2002-04-26 2002-04-26
US60/376,121 2002-04-26
US44086503P 2003-01-16 2003-01-16
US60/440,856 2003-01-16
PCT/US2003/010682 WO2003091227A1 (en) 2002-04-26 2003-04-22 Tachykinin receptor antagonists

Publications (2)

Publication Number Publication Date
CN1649849A CN1649849A (zh) 2005-08-03
CN1313450C true CN1313450C (zh) 2007-05-02

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CNB03809360XA Expired - Fee Related CN1313450C (zh) 2002-04-26 2003-04-22 速激肽受体拮抗剂

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US (1) US7179804B2 (enExample)
EP (1) EP1501808B1 (enExample)
JP (1) JP4895476B2 (enExample)
CN (1) CN1313450C (enExample)
AT (1) ATE399770T1 (enExample)
BR (1) BR0309486A (enExample)
CA (1) CA2484188C (enExample)
CY (1) CY1108539T1 (enExample)
DE (1) DE60321907D1 (enExample)
DK (1) DK1501808T3 (enExample)
ES (1) ES2307925T3 (enExample)
IL (1) IL164787A0 (enExample)
MX (1) MXPA04010625A (enExample)
PT (1) PT1501808E (enExample)
SI (1) SI1501808T1 (enExample)
WO (1) WO2003091227A1 (enExample)

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MXPA04010622A (es) * 2002-04-26 2005-01-25 Lilly Co Eli Derivados de triazol como antagonistas de receptor de taquicinina.
US20060160794A1 (en) * 2003-06-12 2006-07-20 Amegadzie Albert K Tachykinin receptor antagonists
EP1669348A4 (en) * 2003-09-30 2009-03-11 Eisai R&D Man Co Ltd NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
US20090227799A1 (en) * 2004-08-09 2009-09-10 Kazutaka Nakamoto Novel Antimalarial Agent Containing Heterocyclic Compound
JP4874958B2 (ja) * 2005-03-30 2012-02-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピリジン誘導体を含有する抗真菌剤
WO2006132197A1 (ja) * 2005-06-07 2006-12-14 Shionogi & Co., Ltd. I型11βヒドロキシステロイド脱水素酵素阻害活性を有するヘテロ環化合物
CN101228137B (zh) * 2005-07-25 2010-09-29 弗·哈夫曼-拉罗切有限公司 被取代的三唑衍生物和它们作为神经激肽3受体拮抗剂的用途
TWI385169B (zh) * 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd 經雜環取代之吡啶衍生物及含有彼之抗真菌劑
EP1946840B1 (en) * 2005-11-04 2019-08-21 NGK Insulators, Ltd. Honeycomb structure and honeycomb catalyst
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