JP4895476B2 - タキキニン受容体アンタゴニスト - Google Patents

タキキニン受容体アンタゴニスト Download PDF

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JP4895476B2
JP4895476B2 JP2003587787A JP2003587787A JP4895476B2 JP 4895476 B2 JP4895476 B2 JP 4895476B2 JP 2003587787 A JP2003587787 A JP 2003587787A JP 2003587787 A JP2003587787 A JP 2003587787A JP 4895476 B2 JP4895476 B2 JP 4895476B2
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phenyl
trifluoromethyl
bis
benzyl
formula
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Japanese (ja)
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JP2005534627A5 (enExample
JP2005534627A (ja
Inventor
アルバート・クゾビ・アメガジエ
ケビン・マシュー・ガーディニアー
エリック・ジェイムズ・ヘンバー
ホン・ジャン・エリック
ルイス・ニコラウス・ジュンガイム
マイケル・アラン・ロバートソン
ケネス・アレン・セイビン
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イーライ リリー アンド カンパニー
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Otolaryngology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
JP2003587787A 2002-04-26 2003-04-22 タキキニン受容体アンタゴニスト Expired - Fee Related JP4895476B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US37612102P 2002-04-26 2002-04-26
US60/376,121 2002-04-26
US44086503P 2003-01-16 2003-01-16
US60/440,865 2003-01-16
PCT/US2003/010682 WO2003091227A1 (en) 2002-04-26 2003-04-22 Tachykinin receptor antagonists

Publications (3)

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JP2005534627A JP2005534627A (ja) 2005-11-17
JP2005534627A5 JP2005534627A5 (enExample) 2006-06-15
JP4895476B2 true JP4895476B2 (ja) 2012-03-14

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US (1) US7179804B2 (enExample)
EP (1) EP1501808B1 (enExample)
JP (1) JP4895476B2 (enExample)
CN (1) CN1313450C (enExample)
AT (1) ATE399770T1 (enExample)
BR (1) BR0309486A (enExample)
CA (1) CA2484188C (enExample)
CY (1) CY1108539T1 (enExample)
DE (1) DE60321907D1 (enExample)
DK (1) DK1501808T3 (enExample)
ES (1) ES2307925T3 (enExample)
IL (1) IL164787A0 (enExample)
MX (1) MXPA04010625A (enExample)
PT (1) PT1501808E (enExample)
SI (1) SI1501808T1 (enExample)
WO (1) WO2003091227A1 (enExample)

Families Citing this family (27)

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Publication number Priority date Publication date Assignee Title
EA007720B1 (ru) * 2002-04-26 2006-12-29 Эли Лилли Энд Компани Производные триазола в качестве антагонистов рецептора тахикинина
US20060160794A1 (en) * 2003-06-12 2006-07-20 Amegadzie Albert K Tachykinin receptor antagonists
EP1669348A4 (en) * 2003-09-30 2009-03-11 Eisai R&D Man Co Ltd NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND
US20050241110A1 (en) * 2004-04-09 2005-11-03 Bruce Baker Ergonomic handles, especially for garden tools
US20090227799A1 (en) * 2004-08-09 2009-09-10 Kazutaka Nakamoto Novel Antimalarial Agent Containing Heterocyclic Compound
JP4874958B2 (ja) 2005-03-30 2012-02-15 エーザイ・アール・アンド・ディー・マネジメント株式会社 ピリジン誘導体を含有する抗真菌剤
TW200716576A (en) * 2005-06-07 2007-05-01 Shionogi & Co Heterocyclic derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
US20110060017A1 (en) * 2008-03-11 2011-03-10 Neurosearch A/S Novel 1,2,3-triazole derivatives useful as modulators of nicotinic acetylcholine receptors
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AU2003224868A1 (en) 2003-11-10
CY1108539T1 (el) 2012-05-23
IL164787A0 (en) 2005-12-18
ATE399770T1 (de) 2008-07-15
EP1501808A1 (en) 2005-02-02
BR0309486A (pt) 2005-02-09
CN1313450C (zh) 2007-05-02
SI1501808T1 (sl) 2008-10-31
PT1501808E (pt) 2008-09-26
DK1501808T3 (da) 2008-10-13
CA2484188C (en) 2010-11-09
CN1649849A (zh) 2005-08-03
CA2484188A1 (en) 2003-11-06
DE60321907D1 (de) 2008-08-14
MXPA04010625A (es) 2004-12-13
WO2003091227A1 (en) 2003-11-06
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JP2005534627A (ja) 2005-11-17
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