CY1108539T1 - Ανταγωνιστες υποδοχεα ταχυκινινης - Google Patents
Ανταγωνιστες υποδοχεα ταχυκινινηςInfo
- Publication number
- CY1108539T1 CY1108539T1 CY20081100968T CY081100968T CY1108539T1 CY 1108539 T1 CY1108539 T1 CY 1108539T1 CY 20081100968 T CY20081100968 T CY 20081100968T CY 081100968 T CY081100968 T CY 081100968T CY 1108539 T1 CY1108539 T1 CY 1108539T1
- Authority
- CY
- Cyprus
- Prior art keywords
- receptor antagonists
- tachykinin receptor
- tachykinin
- tachykinins
- selective
- Prior art date
Links
- 239000002462 tachykinin receptor antagonist Substances 0.000 title 1
- 102000002002 Neurokinin-1 Receptors Human genes 0.000 abstract 1
- 108010040718 Neurokinin-1 Receptors Proteins 0.000 abstract 1
- 102000003141 Tachykinin Human genes 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 108060008037 tachykinin Proteins 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Addiction (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
Abstract
Η παρούσα εφεύρεση αφορά εκλεκτικούς ανταγωνιστές υποδοχέα ΝΚ-1 του Τύπου (Ι) ή φαρμακευτικώς αποδεκτό άλας αυτών για τη θεραπεία διαταραχών που συνδυάζονται με περίσσεια ταχυκινινών.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37612102P | 2002-04-26 | 2002-04-26 | |
US44086503P | 2003-01-16 | 2003-01-16 | |
PCT/US2003/010682 WO2003091227A1 (en) | 2002-04-26 | 2003-04-22 | Tachykinin receptor antagonists |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1108539T1 true CY1108539T1 (el) | 2012-05-23 |
Family
ID=29273048
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20081100968T CY1108539T1 (el) | 2002-04-26 | 2008-09-10 | Ανταγωνιστες υποδοχεα ταχυκινινης |
Country Status (16)
Country | Link |
---|---|
US (1) | US7179804B2 (el) |
EP (1) | EP1501808B1 (el) |
JP (1) | JP4895476B2 (el) |
CN (1) | CN1313450C (el) |
AT (1) | ATE399770T1 (el) |
BR (1) | BR0309486A (el) |
CA (1) | CA2484188C (el) |
CY (1) | CY1108539T1 (el) |
DE (1) | DE60321907D1 (el) |
DK (1) | DK1501808T3 (el) |
ES (1) | ES2307925T3 (el) |
IL (1) | IL164787A0 (el) |
MX (1) | MXPA04010625A (el) |
PT (1) | PT1501808E (el) |
SI (1) | SI1501808T1 (el) |
WO (1) | WO2003091227A1 (el) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ535886A (en) * | 2002-04-26 | 2007-07-27 | Lilly Co Eli | Triazole derivatives as tachykinin receptor antagonists |
EP1638944A1 (en) * | 2003-06-12 | 2006-03-29 | Eli Lilly And Company | Tachykinin receptor antagonists |
JP4795022B2 (ja) * | 2003-09-30 | 2011-10-19 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環化合物を含有する新規な抗真菌剤 |
US20050241110A1 (en) * | 2004-04-09 | 2005-11-03 | Bruce Baker | Ergonomic handles, especially for garden tools |
JPWO2006016548A1 (ja) * | 2004-08-09 | 2008-05-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ヘテロ環化合物を含有する新規な抗マラリア剤 |
EP1864980A4 (en) * | 2005-03-30 | 2010-08-18 | Eisai R&D Man Co Ltd | A PYRIDINE DERIVATIVE ANTIPILIC AGENT |
JP5147109B2 (ja) * | 2005-06-07 | 2013-02-20 | 塩野義製薬株式会社 | I型11βヒドロキシステロイド脱水素酵素阻害活性を有するヘテロ環化合物 |
CN101228137B (zh) * | 2005-07-25 | 2010-09-29 | 弗·哈夫曼-拉罗切有限公司 | 被取代的三唑衍生物和它们作为神经激肽3受体拮抗剂的用途 |
TWI385169B (zh) * | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
WO2007052479A1 (ja) * | 2005-11-04 | 2007-05-10 | Ngk Insulators, Ltd. | ハニカム構造体及びハニカム触媒体 |
WO2008035726A1 (fr) * | 2006-09-21 | 2008-03-27 | Eisai R & D Management Co., Ltd. | Dérivé de pyridine substitué par un cycle hétéroaryle, et agent antifongique le comprenant |
CN102702185A (zh) * | 2007-04-27 | 2012-10-03 | 卫材R&D管理有限公司 | 杂环取代吡啶衍生物的盐的结晶 |
TW200841879A (en) * | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
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CN103073513B (zh) * | 2012-12-14 | 2015-12-02 | 雅本化学股份有限公司 | 1-取代-5-氯-2h-1,2,3-三氮唑-4-羧酸衍生物及其制备方法 |
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IL50699A0 (en) | 1975-10-28 | 1976-12-31 | Ici America Inc | Triazole derivatives |
AU7947594A (en) * | 1993-10-27 | 1995-05-22 | Merck Sharp & Dohme Limited | Substituted amides as tachykinin antagonists |
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TWI287003B (en) | 2000-07-24 | 2007-09-21 | Hoffmann La Roche | 4-phenyl-pyridine derivatives |
DE10036818A1 (de) * | 2000-07-28 | 2002-02-07 | Solvay Pharm Gmbh | Neue N-Triazolylmethyl-Piperazinderivate als Neurokininrezeptor-Antagonisten |
JP2002123925A (ja) | 2000-10-13 | 2002-04-26 | Fuji Photo Film Co Ltd | 磁気記録媒体 |
-
2003
- 2003-04-22 WO PCT/US2003/010682 patent/WO2003091227A1/en active Application Filing
- 2003-04-22 DE DE60321907T patent/DE60321907D1/de not_active Expired - Lifetime
- 2003-04-22 ES ES03721561T patent/ES2307925T3/es not_active Expired - Lifetime
- 2003-04-22 EP EP03721561A patent/EP1501808B1/en not_active Expired - Lifetime
- 2003-04-22 SI SI200331308T patent/SI1501808T1/sl unknown
- 2003-04-22 CN CNB03809360XA patent/CN1313450C/zh not_active Expired - Fee Related
- 2003-04-22 BR BR0309486-3A patent/BR0309486A/pt not_active IP Right Cessation
- 2003-04-22 PT PT03721561T patent/PT1501808E/pt unknown
- 2003-04-22 DK DK03721561T patent/DK1501808T3/da active
- 2003-04-22 CA CA2484188A patent/CA2484188C/en not_active Expired - Fee Related
- 2003-04-22 IL IL16478703A patent/IL164787A0/xx unknown
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- 2003-04-22 AT AT03721561T patent/ATE399770T1/de not_active IP Right Cessation
- 2003-04-22 MX MXPA04010625A patent/MXPA04010625A/es active IP Right Grant
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US20050239776A1 (en) | 2005-10-27 |
ATE399770T1 (de) | 2008-07-15 |
AU2003224868A1 (en) | 2003-11-10 |
CA2484188C (en) | 2010-11-09 |
SI1501808T1 (sl) | 2008-10-31 |
EP1501808B1 (en) | 2008-07-02 |
MXPA04010625A (es) | 2004-12-13 |
BR0309486A (pt) | 2005-02-09 |
IL164787A0 (en) | 2005-12-18 |
CN1313450C (zh) | 2007-05-02 |
US7179804B2 (en) | 2007-02-20 |
ES2307925T3 (es) | 2008-12-01 |
DK1501808T3 (da) | 2008-10-13 |
JP4895476B2 (ja) | 2012-03-14 |
WO2003091227A1 (en) | 2003-11-06 |
CN1649849A (zh) | 2005-08-03 |
EP1501808A1 (en) | 2005-02-02 |
AU2003224868B2 (en) | 2008-11-20 |
DE60321907D1 (de) | 2008-08-14 |
JP2005534627A (ja) | 2005-11-17 |
CA2484188A1 (en) | 2003-11-06 |
PT1501808E (pt) | 2008-09-26 |
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