CN1296474A - 烷基化用于制备基质金属蛋白酶抑制剂的受阻磺酰胺的方法 - Google Patents
烷基化用于制备基质金属蛋白酶抑制剂的受阻磺酰胺的方法 Download PDFInfo
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- CN1296474A CN1296474A CN99804961A CN99804961A CN1296474A CN 1296474 A CN1296474 A CN 1296474A CN 99804961 A CN99804961 A CN 99804961A CN 99804961 A CN99804961 A CN 99804961A CN 1296474 A CN1296474 A CN 1296474A
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- aryl
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- alkoxyl group
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
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- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8131098P | 1998-04-10 | 1998-04-10 | |
US60/081,310 | 1998-04-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1296474A true CN1296474A (zh) | 2001-05-23 |
Family
ID=22163376
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN99104932A Pending CN1234396A (zh) | 1998-04-10 | 1999-04-09 | 烷基化受阻磺酰胺的方法 |
CN99804961A Pending CN1296474A (zh) | 1998-04-10 | 1999-04-09 | 烷基化用于制备基质金属蛋白酶抑制剂的受阻磺酰胺的方法 |
CN00126476A Pending CN1288885A (zh) | 1998-04-10 | 2000-08-25 | 受阻磺酰胺的烷基化方法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN99104932A Pending CN1234396A (zh) | 1998-04-10 | 1999-04-09 | 烷基化受阻磺酰胺的方法 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN00126476A Pending CN1288885A (zh) | 1998-04-10 | 2000-08-25 | 受阻磺酰胺的烷基化方法 |
Country Status (47)
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6458822B2 (en) | 2000-03-13 | 2002-10-01 | Pfizer Inc. | 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases |
EP1134207A1 (en) * | 2000-03-15 | 2001-09-19 | Pfizer Products Inc. | Process for preparing resorcinol derivatives |
JP4008708B2 (ja) * | 2000-04-07 | 2007-11-14 | サムスン エレクトロニクス カンパニー リミテッド | マトリックスメタロプロテイナーゼの阻害剤としてのスルホンアミド誘導体 |
US20020073441A1 (en) | 2000-12-13 | 2002-06-13 | Ross Brian D. | Compositions and methods for detecting proteolytic activity |
US6844373B2 (en) * | 2002-05-28 | 2005-01-18 | Alcatel | Composition comprising fluorinated, radiation-curable dyes for surface energy control |
ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
ITFI20040174A1 (it) * | 2004-08-03 | 2004-11-03 | Protera S R L | Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi |
ITBO20050005U1 (it) * | 2005-01-31 | 2006-08-01 | Ali Spa | Distributore di bevande ghiacciate e simili |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU523636A3 (ru) * | 1973-06-18 | 1976-07-30 | Стауффер Кемикал Компани (Фирма) | Способ получени сульфоксидных или сульфоновых производных тиокарбаматов |
ZA794723B (en) | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
GB9000725D0 (en) | 1990-01-12 | 1990-03-14 | Pfizer Ltd | Therapeutic agents |
US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
CA2264284A1 (en) * | 1996-08-23 | 1998-02-26 | Ralph P. Robinson | Arylsulfonylamino hydroxamic acid derivatives |
JP3765584B2 (ja) | 1997-02-03 | 2006-04-12 | ファイザー・プロダクツ・インク | アリールスルホニルアミノヒドロキサム酸誘導体 |
ES2176913T3 (es) | 1997-08-08 | 2002-12-01 | Pfizer Prod Inc | Derivados de acidos arilsulfonilaminohidroxamicos. |
SK1362000A3 (en) | 1997-08-08 | 2000-10-09 | Pfizer Prod Inc | Aryloxyarylsulfonylamino hydroxamic acid derivatives |
PA8469401A1 (es) | 1998-04-10 | 2000-05-24 | Pfizer Prod Inc | Derivados biciclicos del acido hidroxamico |
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