ID27208A - Proses untuk alkilasi sulfonamida-sulfonamida yang terhalang yang berguna dalam produksi penghambat-penghambat metaloproteinase matriks - Google Patents

Proses untuk alkilasi sulfonamida-sulfonamida yang terhalang yang berguna dalam produksi penghambat-penghambat metaloproteinase matriks

Info

Publication number
ID27208A
ID27208A IDW20002031A ID20002031A ID27208A ID 27208 A ID27208 A ID 27208A ID W20002031 A IDW20002031 A ID W20002031A ID 20002031 A ID20002031 A ID 20002031A ID 27208 A ID27208 A ID 27208A
Authority
ID
Indonesia
Prior art keywords
matriers
metaloproteinase
allegation
understanded
sulfonamides
Prior art date
Application number
IDW20002031A
Other languages
English (en)
Inventor
Brian M Andresen
Philip D Hammen
Joel M Hawkins
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ID27208A publication Critical patent/ID27208A/id

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Psychology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
IDW20002031A 1998-04-10 1999-04-09 Proses untuk alkilasi sulfonamida-sulfonamida yang terhalang yang berguna dalam produksi penghambat-penghambat metaloproteinase matriks ID27208A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8131098P 1998-04-10 1998-04-10

Publications (1)

Publication Number Publication Date
ID27208A true ID27208A (id) 2001-03-08

Family

ID=22163376

Family Applications (2)

Application Number Title Priority Date Filing Date
IDP990304D ID23244A (id) 1998-04-10 1999-04-05 Proses alkilasi sulfonamida terhalang
IDW20002031A ID27208A (id) 1998-04-10 1999-04-09 Proses untuk alkilasi sulfonamida-sulfonamida yang terhalang yang berguna dalam produksi penghambat-penghambat metaloproteinase matriks

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IDP990304D ID23244A (id) 1998-04-10 1999-04-05 Proses alkilasi sulfonamida terhalang

Country Status (47)

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US (2) US6114568A (id)
EP (2) EP0949245B1 (id)
JP (2) JP3479511B2 (id)
KR (2) KR100357660B1 (id)
CN (3) CN1296474A (id)
AP (1) AP1095A (id)
AR (1) AR017731A1 (id)
AT (2) ATE206392T1 (id)
AU (2) AU760213B2 (id)
BG (1) BG63665B1 (id)
BR (2) BR9910110A (id)
CA (2) CA2268684C (id)
CO (1) CO4810299A1 (id)
DE (2) DE69900321T2 (id)
DK (1) DK0949245T3 (id)
DZ (1) DZ2754A1 (id)
EA (1) EA002277B1 (id)
EG (1) EG21985A (id)
ES (2) ES2163316T3 (id)
GT (1) GT199900047A (id)
HN (1) HN1999000043A (id)
HR (1) HRP990106B1 (id)
HU (2) HUP0101465A3 (id)
ID (2) ID23244A (id)
IL (2) IL129168A (id)
IN (1) IN192485B (id)
IS (1) IS5018A (id)
MA (1) MA24833A1 (id)
NO (1) NO991675L (id)
NZ (1) NZ335105A (id)
OA (1) OA11030A (id)
PA (1) PA8469601A1 (id)
PE (1) PE20000417A1 (id)
PL (2) PL332451A1 (id)
PT (1) PT949245E (id)
RU (1) RU2197479C2 (id)
SA (1) SA99200089A (id)
SG (1) SG75167A1 (id)
SK (1) SK45399A3 (id)
TN (1) TNSN99054A1 (id)
TR (2) TR199900756A2 (id)
TW (1) TW520354B (id)
UA (1) UA57039C2 (id)
UY (1) UY25469A1 (id)
WO (1) WO1999052862A1 (id)
YU (1) YU18399A (id)
ZA (2) ZA992627B (id)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458822B2 (en) 2000-03-13 2002-10-01 Pfizer Inc. 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases
EP1134207A1 (en) * 2000-03-15 2001-09-19 Pfizer Products Inc. Process for preparing resorcinol derivatives
US6548667B2 (en) 2000-04-07 2003-04-15 Samsung Electronics Co. Ltd. Sulfonamide derivative as a matrix metalloproteinase inhibitor
US20020073441A1 (en) 2000-12-13 2002-06-13 Ross Brian D. Compositions and methods for detecting proteolytic activity
US6844373B2 (en) * 2002-05-28 2005-01-18 Alcatel Composition comprising fluorinated, radiation-curable dyes for surface energy control
JP2006516548A (ja) 2002-12-30 2006-07-06 アンジオテック インターナショナル アクツィエン ゲゼルシャフト 迅速ゲル化ポリマー組成物からの薬物送達法
ITFI20040174A1 (it) * 2004-08-03 2004-11-03 Protera S R L Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi
ITBO20050005U1 (it) * 2005-01-31 2006-08-01 Ali Spa Distributore di bevande ghiacciate e simili

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA794723B (en) 1978-09-11 1980-08-27 Univ Miami Anti-hypertensive agents
GB9000725D0 (en) 1990-01-12 1990-03-14 Pfizer Ltd Therapeutic agents
US5506242A (en) 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
PL331895A1 (en) * 1996-08-23 1999-08-16 Pfizer Arylosulphonylamino derivatives of hydroxamic acid
BR9807815A (pt) 1997-02-03 2000-03-08 Pfizer Prod Inc Derivados de ácido arilsulfonilamino-hidroxâmico
DK0895988T3 (da) 1997-08-08 2002-09-09 Pfizer Prod Inc Arylsulfonylaminohydroxamsyrederivater
EA002490B1 (ru) 1997-08-08 2002-06-27 Пфайзер Продактс Инк. Производные арилоксиарилсульфониламиногидроксамовой кислоты
PA8469401A1 (es) 1998-04-10 2000-05-24 Pfizer Prod Inc Derivados biciclicos del acido hidroxamico

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CA2327498C (en) 2006-01-31
CN1296474A (zh) 2001-05-23
EA199900277A2 (ru) 1999-10-28
NO991675L (no) 1999-10-11
AU760213B2 (en) 2003-05-08
OA11030A (en) 2002-02-07
HUP0101465A3 (en) 2002-11-28
IS5018A (is) 1999-10-11
ZA992627B (en) 2000-10-09
JP3540959B2 (ja) 2004-07-07
PL343530A1 (en) 2001-08-27
KR20010042567A (ko) 2001-05-25
EG21985A (en) 2002-05-31
HRP990106B1 (en) 2003-08-31
TW520354B (en) 2003-02-11
DZ2754A1 (fr) 2003-09-15
DE69922638D1 (de) 2005-01-20
MA24833A1 (fr) 1999-12-31
US6229025B1 (en) 2001-05-08
SG75167A1 (en) 2000-09-19
DE69922638T2 (de) 2005-05-19
IL129168A0 (en) 2000-02-17
SA99200089A (ar) 2005-12-03
TR200002950T2 (tr) 2000-12-21
BR9910110A (pt) 2001-10-09
HU9901043D0 (en) 1999-06-28
CN1234396A (zh) 1999-11-10
ATE284864T1 (de) 2005-01-15
SK45399A3 (en) 2000-08-14
HN1999000043A (es) 1999-11-03
AU3552799A (en) 1999-11-01
CO4810299A1 (es) 1999-06-30
CA2268684A1 (en) 1999-10-10
CA2327498A1 (en) 1999-10-21
JP3479511B2 (ja) 2003-12-15
HUP0101465A2 (hu) 2002-03-28
ATE206392T1 (de) 2001-10-15
AU755004B2 (en) 2002-11-28
DE69900321T2 (de) 2002-07-11
HRP990106A2 (en) 1999-12-31
EA002277B1 (ru) 2002-02-28
WO1999052862A1 (en) 1999-10-21
EP0949245A1 (en) 1999-10-13
ES2163316T3 (es) 2002-01-16
DK0949245T3 (da) 2002-01-28
KR19990082986A (ko) 1999-11-25
JP2002511447A (ja) 2002-04-16
CN1288885A (zh) 2001-03-28
AR017731A1 (es) 2001-09-12
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BG103320A (en) 2001-08-31
US6114568A (en) 2000-09-05
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EP1068180A1 (en) 2001-01-17
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PA8469601A1 (es) 2000-09-29
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KR100377718B1 (ko) 2003-03-26
RU2197479C2 (ru) 2003-01-27
IN192485B (id) 2004-04-24
YU18399A (sh) 2002-11-15
GT199900047A (es) 2000-09-15
EP0949245B1 (en) 2001-10-04
JP2000026400A (ja) 2000-01-25
TR199900756A2 (xx) 1999-11-22
TNSN99054A1 (fr) 2005-11-10
NZ335105A (en) 2000-03-27
BR9902219A (pt) 2000-04-11
ZA200005370B (en) 2002-01-03
PE20000417A1 (es) 2000-05-24
BG63665B1 (bg) 2002-08-30
IL138778A0 (en) 2001-10-31
HUP9901043A1 (hu) 2000-08-28
ID23244A (id) 2000-03-30
NO991675D0 (no) 1999-04-09
DE69900321D1 (de) 2001-11-08
UY25469A1 (es) 1999-11-17
CA2268684C (en) 2004-07-13
AU2369199A (en) 1999-10-21
UA57039C2 (uk) 2003-06-16
EA199900277A3 (ru) 2000-04-24

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