HRP990106B1 - Process for alkylating hindered sulfonamides - Google Patents
Process for alkylating hindered sulfonamidesInfo
- Publication number
- HRP990106B1 HRP990106B1 HR990106A HRP990106A HRP990106B1 HR P990106 B1 HRP990106 B1 HR P990106B1 HR 990106 A HR990106 A HR 990106A HR P990106 A HRP990106 A HR P990106A HR P990106 B1 HRP990106 B1 HR P990106B1
- Authority
- HR
- Croatia
- Prior art keywords
- alkylating
- sulfonamides
- hindered sulfonamides
- alkylating hindered
- hindered
- Prior art date
Links
- 230000002152 alkylating effect Effects 0.000 title 1
- 229940124530 sulfonamide Drugs 0.000 title 1
- 150000003456 sulfonamides Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/08—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/14—Nitrogen atoms not forming part of a nitro radical
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Vascular Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8131098P | 1998-04-10 | 1998-04-10 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP990106A2 HRP990106A2 (en) | 1999-12-31 |
| HRP990106B1 true HRP990106B1 (en) | 2003-08-31 |
Family
ID=22163376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR990106A HRP990106B1 (en) | 1998-04-10 | 1999-04-09 | Process for alkylating hindered sulfonamides |
Country Status (47)
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6458822B2 (en) | 2000-03-13 | 2002-10-01 | Pfizer Inc. | 2-oxo-imidazolidine-4-carboxylic acid hydroxamide compounds that inhibit matrix metalloproteinases |
| EP1134207A1 (en) * | 2000-03-15 | 2001-09-19 | Pfizer Products Inc. | Process for preparing resorcinol derivatives |
| JP4008708B2 (ja) * | 2000-04-07 | 2007-11-14 | サムスン エレクトロニクス カンパニー リミテッド | マトリックスメタロプロテイナーゼの阻害剤としてのスルホンアミド誘導体 |
| US20020073441A1 (en) | 2000-12-13 | 2002-06-13 | Ross Brian D. | Compositions and methods for detecting proteolytic activity |
| US6844373B2 (en) * | 2002-05-28 | 2005-01-18 | Alcatel | Composition comprising fluorinated, radiation-curable dyes for surface energy control |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| ITFI20040174A1 (it) * | 2004-08-03 | 2004-11-03 | Protera S R L | Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi |
| ITBO20050005U1 (it) * | 2005-01-31 | 2006-08-01 | Ali Spa | Distributore di bevande ghiacciate e simili |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU523636A3 (ru) * | 1973-06-18 | 1976-07-30 | Стауффер Кемикал Компани (Фирма) | Способ получени сульфоксидных или сульфоновых производных тиокарбаматов |
| ZA794723B (en) | 1978-09-11 | 1980-08-27 | Univ Miami | Anti-hypertensive agents |
| GB9000725D0 (en) | 1990-01-12 | 1990-03-14 | Pfizer Ltd | Therapeutic agents |
| US5506242A (en) | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| CA2264284A1 (en) * | 1996-08-23 | 1998-02-26 | Ralph P. Robinson | Arylsulfonylamino hydroxamic acid derivatives |
| JP3765584B2 (ja) | 1997-02-03 | 2006-04-12 | ファイザー・プロダクツ・インク | アリールスルホニルアミノヒドロキサム酸誘導体 |
| ES2176913T3 (es) | 1997-08-08 | 2002-12-01 | Pfizer Prod Inc | Derivados de acidos arilsulfonilaminohidroxamicos. |
| SK1362000A3 (en) | 1997-08-08 | 2000-10-09 | Pfizer Prod Inc | Aryloxyarylsulfonylamino hydroxamic acid derivatives |
| PA8469401A1 (es) | 1998-04-10 | 2000-05-24 | Pfizer Prod Inc | Derivados biciclicos del acido hidroxamico |
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1999
- 1999-03-24 PA PA19998469601A patent/PA8469601A1/es unknown
- 1999-03-25 DK DK99302287T patent/DK0949245T3/da active
- 1999-03-25 GT GT199900047A patent/GT199900047A/es unknown
- 1999-03-25 PT PT99302287T patent/PT949245E/pt unknown
- 1999-03-25 EP EP99302287A patent/EP0949245B1/en not_active Expired - Lifetime
- 1999-03-25 AT AT99302287T patent/ATE206392T1/de not_active IP Right Cessation
- 1999-03-25 ES ES99302287T patent/ES2163316T3/es not_active Expired - Lifetime
- 1999-03-25 IL IL12916899A patent/IL129168A/xx not_active IP Right Cessation
- 1999-03-25 DE DE69900321T patent/DE69900321T2/de not_active Expired - Fee Related
- 1999-04-01 OA OA9900073A patent/OA11030A/en unknown
- 1999-04-05 ID IDP990304D patent/ID23244A/id unknown
- 1999-04-06 IS IS5018A patent/IS5018A/is unknown
- 1999-04-06 PE PE1999000277A patent/PE20000417A1/es not_active Application Discontinuation
- 1999-04-07 KR KR1019990011957A patent/KR100357660B1/ko not_active Expired - Fee Related
- 1999-04-07 SK SK453-99A patent/SK45399A3/sk unknown
- 1999-04-07 IN IN522DE1999 patent/IN192485B/en unknown
- 1999-04-07 TW TW088105541A patent/TW520354B/zh not_active IP Right Cessation
- 1999-04-07 MA MA25530A patent/MA24833A1/fr unknown
- 1999-04-07 TN TNTNSN99054A patent/TNSN99054A1/fr unknown
- 1999-04-07 DZ DZ990055A patent/DZ2754A1/xx active
- 1999-04-08 EG EG37499A patent/EG21985A/xx active
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- 1999-04-08 TR TR1999/00756A patent/TR199900756A2/xx unknown
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- 1999-04-08 YU YU18399A patent/YU18399A/sh unknown
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- 1999-04-09 BG BG103320A patent/BG63665B1/bg unknown
- 1999-04-09 CN CN99104932A patent/CN1234396A/zh active Pending
- 1999-04-09 IL IL13877899A patent/IL138778A0/xx unknown
- 1999-04-09 EP EP99917394A patent/EP1068180B1/en not_active Expired - Lifetime
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- 1999-04-09 US US09/290,022 patent/US6229025B1/en not_active Expired - Fee Related
- 1999-04-09 ES ES99917394T patent/ES2234253T3/es not_active Expired - Lifetime
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- 1999-04-09 HU HU0101465A patent/HUP0101465A3/hu unknown
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- 1999-04-09 US US09/289,454 patent/US6114568A/en not_active Expired - Fee Related
- 1999-04-09 AU AU35527/99A patent/AU760213B2/en not_active Ceased
- 1999-04-09 WO PCT/US1999/007858 patent/WO1999052862A1/en active IP Right Grant
- 1999-04-09 HN HN1999000043A patent/HN1999000043A/es unknown
- 1999-04-09 ID IDW20002031A patent/ID27208A/id unknown
- 1999-04-09 PL PL99343530A patent/PL343530A1/xx unknown
- 1999-04-09 RU RU2000125555/04A patent/RU2197479C2/ru not_active IP Right Cessation
- 1999-04-09 EA EA199900277A patent/EA002277B1/ru not_active IP Right Cessation
- 1999-04-09 CA CA002327498A patent/CA2327498C/en not_active Expired - Fee Related
- 1999-04-09 AU AU23691/99A patent/AU755004B2/en not_active Ceased
- 1999-04-09 NZ NZ335105A patent/NZ335105A/xx unknown
- 1999-04-09 UA UA99042034A patent/UA57039C2/uk unknown
- 1999-04-09 PL PL99332451A patent/PL332451A1/xx unknown
- 1999-04-09 JP JP2000543425A patent/JP3479511B2/ja not_active Expired - Fee Related
- 1999-04-09 HU HU9901043A patent/HUP9901043A1/hu unknown
- 1999-04-09 TR TR2000/02950T patent/TR200002950T2/xx unknown
- 1999-04-09 BR BR9910110-6A patent/BR9910110A/pt not_active IP Right Cessation
- 1999-04-09 BR BR9902219-2A patent/BR9902219A/pt not_active IP Right Cessation
- 1999-04-12 JP JP10387399A patent/JP3540959B2/ja not_active Expired - Fee Related
- 1999-04-12 UY UY25469A patent/UY25469A1/es unknown
- 1999-04-12 CO CO99021411A patent/CO4810299A1/es unknown
- 1999-05-05 SA SA99200089A patent/SA99200089A/ar unknown
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2000
- 2000-08-25 CN CN00126476A patent/CN1288885A/zh active Pending
- 2000-10-02 ZA ZA200005370A patent/ZA200005370B/en unknown
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