CN1261281A - 肽甲状旁腺激素类似物 - Google Patents

肽甲状旁腺激素类似物 Download PDF

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Publication number
CN1261281A
CN1261281A CN98806651A CN98806651A CN1261281A CN 1261281 A CN1261281 A CN 1261281A CN 98806651 A CN98806651 A CN 98806651A CN 98806651 A CN98806651 A CN 98806651A CN 1261281 A CN1261281 A CN 1261281A
Authority
CN
China
Prior art keywords
nle
seq
hpth
lys
fmoc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN98806651A
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English (en)
Chinese (zh)
Inventor
S·M·康顿
I·毛里兹
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Rhone Poulenc Rorer Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Pharmaceuticals Inc filed Critical Rhone Poulenc Rorer Pharmaceuticals Inc
Publication of CN1261281A publication Critical patent/CN1261281A/zh
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Genetics & Genomics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN98806651A 1997-05-14 1998-05-13 肽甲状旁腺激素类似物 Pending CN1261281A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4647297P 1997-05-14 1997-05-14
US60/046,472 1997-05-14

Publications (1)

Publication Number Publication Date
CN1261281A true CN1261281A (zh) 2000-07-26

Family

ID=21943653

Family Applications (1)

Application Number Title Priority Date Filing Date
CN98806651A Pending CN1261281A (zh) 1997-05-14 1998-05-13 肽甲状旁腺激素类似物

Country Status (20)

Country Link
US (2) US6472505B1 (enExample)
EP (1) EP0986395A4 (enExample)
JP (1) JP2001517957A (enExample)
KR (1) KR100351213B1 (enExample)
CN (1) CN1261281A (enExample)
AP (1) AP9901686A0 (enExample)
AU (1) AU746461B2 (enExample)
BG (1) BG103957A (enExample)
BR (1) BR9808786A (enExample)
CA (1) CA2290443A1 (enExample)
EA (1) EA002819B1 (enExample)
HU (1) HUP0003349A3 (enExample)
IL (1) IL132901A0 (enExample)
NO (1) NO995568L (enExample)
OA (1) OA11216A (enExample)
PL (1) PL336803A1 (enExample)
SK (1) SK151599A3 (enExample)
UA (1) UA62967C2 (enExample)
WO (1) WO1998051324A1 (enExample)
ZA (1) ZA984077B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101522709B (zh) * 2006-10-13 2013-03-20 伊莱利利公司 作为pth受体调节剂的聚乙二醇化的pth及其用途

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Cited By (1)

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Publication number Priority date Publication date Assignee Title
CN101522709B (zh) * 2006-10-13 2013-03-20 伊莱利利公司 作为pth受体调节剂的聚乙二醇化的pth及其用途

Also Published As

Publication number Publication date
AU746461B2 (en) 2002-05-02
HUP0003349A2 (hu) 2001-01-29
HUP0003349A3 (en) 2001-12-28
US6472505B1 (en) 2002-10-29
BR9808786A (pt) 2000-07-11
IL132901A0 (en) 2001-03-19
EA199901025A1 (ru) 2000-06-26
EP0986395A4 (en) 2004-12-01
CA2290443A1 (en) 1998-11-19
KR100351213B1 (ko) 2002-09-05
EP0986395A1 (en) 2000-03-22
US20020132973A1 (en) 2002-09-19
AP9901686A0 (en) 1999-12-31
WO1998051324A1 (en) 1998-11-19
ZA984077B (en) 1998-11-24
JP2001517957A (ja) 2001-10-09
AU7386798A (en) 1998-12-08
SK151599A3 (en) 2000-09-12
PL336803A1 (en) 2000-07-17
KR20010012568A (ko) 2001-02-15
UA62967C2 (en) 2004-01-15
NO995568L (no) 1999-12-29
BG103957A (bg) 2000-04-28
NO995568D0 (no) 1999-11-12
OA11216A (en) 2003-07-10
EA002819B1 (ru) 2002-10-31

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