CO4410206A1 - DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN - Google Patents

DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN

Info

Publication number
CO4410206A1
CO4410206A1 CO95032396A CO95032396A CO4410206A1 CO 4410206 A1 CO4410206 A1 CO 4410206A1 CO 95032396 A CO95032396 A CO 95032396A CO 95032396 A CO95032396 A CO 95032396A CO 4410206 A1 CO4410206 A1 CO 4410206A1
Authority
CO
Colombia
Prior art keywords
pthrp
pth
amino acid
acid waste
derivatives
Prior art date
Application number
CO95032396A
Other languages
English (en)
Inventor
Francois Cardinaux
Jean Honore M Feyen
Rainer Gamse
Frank Otto Gombert
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9415255A external-priority patent/GB9415255D0/en
Priority claimed from GB9415254A external-priority patent/GB9415254D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of CO4410206A1 publication Critical patent/CO4410206A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

UN COMPUESTO DE PTH O PTHrP QUE TIENE POTENTE AC- TIVIDAD ANTAGONISTA EN EL RECEPTOR DE PTH/PTHrP EN EL CUAL POR LO MENOS UNO DE LOS RESIDUOS AMINOACI- DOS QUE SE PRESENTA DE MANERA NATURAL EN LAS POSI- CIONES 2 Y 10 ES SUSTITUIDOS POR TRIPTOFANO U OTRO RESIDUO AMINOACIDO QUE PRESENTA UN GRUPO AROMATICO O HETEROAROMATICO EN U CADENA LATERAL, Y DE MANERA OPCIONAL POR LO MENOS UNO DE LOS RESIDUOS AMINOA- CIDOS QUE SE PRESENTA DE MANERA NATURAL EN LAS PO- SICIONES 3 Y 6 ES SUSTITUIDO DE MANERA ADICIONAL POR TRIPTOFANO Y OTRO RESIDUO AMINOACIDO QUE PRE- SENTE UN GRUPO AROMATICO O HETEROAROMATICO EN SU CADENA LATERAL, EN FORMA LIBRE O EN FORMA DE SAL O DE COMPLEJO.
CO95032396A 1994-07-28 1995-07-21 DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN CO4410206A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9415255A GB9415255D0 (en) 1994-07-28 1994-07-28 Organic compounds
GB9415254A GB9415254D0 (en) 1994-07-28 1994-07-28 Organic compounds

Publications (1)

Publication Number Publication Date
CO4410206A1 true CO4410206A1 (es) 1997-01-09

Family

ID=26305357

Family Applications (1)

Application Number Title Priority Date Filing Date
CO95032396A CO4410206A1 (es) 1994-07-28 1995-07-21 DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN

Country Status (15)

Country Link
EP (1) EP0773958A1 (es)
JP (1) JPH10502091A (es)
AU (1) AU3167095A (es)
BR (1) BR9508433A (es)
CA (1) CA2192787A1 (es)
CO (1) CO4410206A1 (es)
CZ (1) CZ23397A3 (es)
FI (1) FI970168A (es)
HU (1) HUT77979A (es)
IL (1) IL114736A0 (es)
NO (1) NO970356D0 (es)
PL (1) PL318017A1 (es)
SK (1) SK12097A3 (es)
TR (1) TR199500915A2 (es)
WO (1) WO1996003437A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW505654B (en) * 1996-07-30 2002-10-11 Hoffmann La Roche Synthesis of analogs of PTH and PTHrP
US6147186A (en) * 1996-07-31 2000-11-14 The General Hospital Corporation Parathyroid hormone-related peptide analogs
KR100847441B1 (ko) 1996-09-26 2008-07-21 츄가이 세이야꾸 가부시키가이샤 인간의 부갑상선 호르몬 관련 펩티드에 대한 항체
BR9808786A (pt) 1997-05-14 2000-07-11 Rhone Poulenc Rorer Pharma Composto peptìdio cìclico ou um seu sal ou pró-medicamento farmaceuticamente aceitáveis, composição farmacêutica, e, processos para tratar doenças associadas com a regulagem do cálcio em um paciente e para tratar a osteopenia ou a osteoporose em um mamìfero hospedeiro
UA74130C2 (uk) * 1997-05-15 2005-11-15 Чугаі Сейяку Кабусікі Кайся ЗАСТОСУВАННЯ АНТИТІЛА ПРОТИ БІЛКА, СПОРІДНЕНОГО З ПАРАТИРЕОЇДНИМ ГОРМОНОМ (PTHrP), АБО ЙОГО ФУНКЦІОНАЛЬНО АКТИВНОГО ФРАГМЕНТА І/АБО ЙОГО МОДИФІКОВАНОГО ФРАГМЕНТА ДЛЯ ВИРОБНИЦТВА ЛІКАРСЬКОГО ЗАСОБУ ДЛЯ ПРОФІЛАКТИКИ АБО ЛІКУВАННЯ КАХЕКСІЇ
WO2001002011A1 (fr) * 1999-07-02 2001-01-11 Chugai Seiyaku Kabushiki Kaisha REMEDES CONTRE LES MALADIES CAUSEES PAR PTH OU PTHrP
TWI255718B (en) 1999-07-02 2006-06-01 Chugai Pharmaceutical Co Ltd Ameliorative agent for low vasopressin concentration
RU2002102916A (ru) * 1999-07-06 2003-11-10 Чугаи Сейяку Кабусики Кайся (Jp) Терапевтический агент для лечения устойчивой к лекраственным препаратам гиперкальциемии
AU7363000A (en) * 1999-09-20 2001-04-24 Eli Lilly And Company Method for reducing the risk of cancer
US20030049211A1 (en) * 2000-01-25 2003-03-13 Atsuhiko Kato Remedies and preventives for dental diseases
WO2001064249A1 (en) * 2000-02-28 2001-09-07 Chugai Seiyaku Kabushiki Kaisha Tissue decomposition inhibitor
DE60137417D1 (de) 2000-04-28 2009-03-05 Chugai Pharmaceutical Co Ltd Zellproliferation-inhibitoren
AU2001278742A1 (en) * 2000-08-16 2002-02-25 Chugai Seiyaku Kabushiki Kaisha Agents for ameliorating symptoms caused by joint diseases
CA3017668C (en) 2007-08-01 2021-11-09 The General Hospital Corporation Screening methods using g-protein coupled receptors and related compositions
MX358161B (es) 2010-05-13 2018-08-06 The General Hospital Corp Star Analogos de hormona paratiroidea y usos para los mismos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2040264A1 (en) * 1990-04-12 1991-10-13 Tatsuhiko Kanmera Parathyroid hormone antagonists
WO1992000753A1 (en) * 1990-07-13 1992-01-23 The Regents Of The University Of California PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9
AU672790B2 (en) * 1992-07-15 1996-10-17 Novartis Ag Variants of parathyroid hormone and its fragments

Also Published As

Publication number Publication date
CZ23397A3 (en) 1997-07-16
NO970356L (no) 1997-01-28
WO1996003437A1 (en) 1996-02-08
CA2192787A1 (en) 1996-02-08
TR199500915A2 (tr) 1996-06-21
AU3167095A (en) 1996-02-22
FI970168A0 (fi) 1997-01-15
HUT77979A (hu) 1999-01-28
JPH10502091A (ja) 1998-02-24
EP0773958A1 (en) 1997-05-21
PL318017A1 (en) 1997-05-12
IL114736A0 (en) 1995-11-27
FI970168A (fi) 1997-01-15
NO970356D0 (no) 1997-01-28
SK12097A3 (en) 1997-08-06
MX9700446A (es) 1998-06-28
BR9508433A (pt) 1998-07-14

Similar Documents

Publication Publication Date Title
CO4410206A1 (es) DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
NO981944D0 (no) Lipopolyaminer som transfeksjonsmidler samt farmas÷ytisk anvendelse derav
MX9203422A (es) Compuestos farmacologicamente activos para el sistema nervioso central.
NL300281I2 (nl) Exenatide, desgewenst in de vorm van een farmaceutisch aanvaardbaar zout
DE69008581T3 (de) Container zum Transport von Geflügel.
DE69300574D1 (de) Vorrichtung zum Halten von Schlachtgeflügel.
EA200100022A1 (ru) Композиции с контролируемым высвобождением пароксетина
DK0909562T3 (da) Injektionspræparat indeholdende en lipid A analog og fremgangsmåde til fremstilling deraf
BR0213355A (pt) composições farmacêuticas
NO993350L (no) Vitronectin-reseptor-antagonister
PT90743A (pt) Processo para a preparacao de derivados de hirudina com accao retardada e de composicoes farmaceuticas que os contem
NO962717D0 (no) Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister
DE69819089D1 (de) Förderanlage zum Transport von Gütern
BR0103048A (pt) Derivados de n-triazolilmetil-piperazina como antagonistas de receptores de neuroquinina
DE69808475T2 (de) Aminosäurederivate zur behandlung von schlaganfall
PT1200400E (pt) Derivados de pirrolidino-2,3,4-trion-3-oxina substituidas com eficacia como antagonistas do receptor nmda
PT952975E (pt) Compostos bi-aromaticos ligados por um radical hetero-etinileno e composicoes farmaceuticas e cosmeticas que os contem
SE8302979D0 (sv) Piperazine derivatives, their production and pharmaceutical compositions containing them
ECSP951488A (es) Peptidos
FI943513A (fi) Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja
DE69004589T2 (de) Förderer, gespeist von mehreren Bahnen.
DE68905919T2 (de) Gasgespeiste Förderbahn.
EA200200491A1 (ru) Замещенные 1,2,3,4,5,6-гексагидро-2,6-метано-3-бензазоцины и их применение в качестве лекарственных средств
DE69903375D1 (de) Fördersystem zum Transport von im wesentlichen zylindrischen Gegenständen wie Kernbrennstofftabletten
DE29904526U1 (de) Möbeleinrichtung zum Tragen von Gegenständen