DE60137417D1 - Zellproliferation-inhibitoren - Google Patents
Zellproliferation-inhibitorenInfo
- Publication number
- DE60137417D1 DE60137417D1 DE60137417T DE60137417T DE60137417D1 DE 60137417 D1 DE60137417 D1 DE 60137417D1 DE 60137417 T DE60137417 T DE 60137417T DE 60137417 T DE60137417 T DE 60137417T DE 60137417 D1 DE60137417 D1 DE 60137417D1
- Authority
- DE
- Germany
- Prior art keywords
- cell proliferation
- proliferation inhibitors
- pthrp
- inhibitors
- proliferation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/29—Parathyroid hormone (parathormone); Parathyroid hormone-related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000131793 | 2000-04-28 | ||
JP2000173834 | 2000-06-09 | ||
PCT/JP2001/003665 WO2001082968A1 (fr) | 2000-04-28 | 2001-04-26 | Inhibiteurs de proliferation cellulaire |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60137417D1 true DE60137417D1 (de) | 2009-03-05 |
Family
ID=26591317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60137417T Expired - Lifetime DE60137417D1 (de) | 2000-04-28 | 2001-04-26 | Zellproliferation-inhibitoren |
Country Status (7)
Country | Link |
---|---|
US (1) | US8029793B2 (de) |
EP (2) | EP1283057B2 (de) |
JP (1) | JP4846169B2 (de) |
AT (1) | ATE420661T1 (de) |
AU (1) | AU2001252618A1 (de) |
DE (1) | DE60137417D1 (de) |
WO (1) | WO2001082968A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2841788B1 (fr) * | 2002-07-05 | 2006-01-27 | Univ Pasteur | Utilisation d'antagonistes de la pthrp pour traiter le carcinome a cellules renales |
JPWO2004045643A1 (ja) * | 2002-11-18 | 2006-03-16 | 中外製薬株式会社 | 軟骨腫・軟骨肉腫治療剤 |
CN1838968A (zh) | 2003-08-08 | 2006-09-27 | 艾伯吉尼斯公司 | 针对甲状旁腺激素(pth)之抗体和其用途 |
US7318925B2 (en) | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
BRPI0507088A (pt) | 2004-01-26 | 2007-06-19 | Renessen Llc | alimento de soja com alto teor de proteìna |
GB2471693A (en) * | 2009-07-08 | 2011-01-12 | Complix Nv | Parathyroid hormone related protein antagonists |
US11717593B2 (en) * | 2013-03-13 | 2023-08-08 | Avery Dennison Corporation | Improving adhesive properties |
Family Cites Families (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
JPH0759763B2 (ja) | 1986-03-24 | 1995-06-28 | 株式会社バイオマテリアル・ユニバース | 高強度、高弾性率ポリビニルアルコ−ル繊維およびその製造法 |
EP0293158A3 (de) | 1987-05-26 | 1990-05-09 | Merck & Co. Inc. | Parathyroide Hormon-Antagonisten |
EP0293130A3 (de) | 1987-05-26 | 1990-06-13 | Merck & Co. Inc. | Dimere von Parathyroid-Hormon-Antagonisten |
US5001223A (en) | 1987-05-26 | 1991-03-19 | Merck & Co., Inc. | Parathyroid hormone antagonists with enhanced metabolic properties |
US4771124A (en) | 1987-05-26 | 1988-09-13 | Merck & Co., Inc. | Parathyroid hormone antagonists with simplified synthetic methodology |
JPS6459878A (en) | 1987-08-31 | 1989-03-07 | Matsushita Electric Ind Co Ltd | Semiconductor laser protective circuit |
DE68908175T2 (de) | 1988-05-27 | 1994-03-03 | Centocor Inc | Gefriergetrocknete formulierung für antikörperprodukte. |
EP0417191B1 (de) | 1988-05-27 | 1993-03-10 | Centocor, Inc. | Formulierung für antikörper enthaltende reagenzien |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
US5217896A (en) | 1988-12-30 | 1993-06-08 | Oncogene Science, Inc. | Monoclonal antibodies recognizing parathyroid hormone-like protein |
JPH02207099A (ja) | 1989-02-07 | 1990-08-16 | Tonen Corp | PTHrP関連ペプチド、その製造法及び用途 |
CA2035179C (en) | 1990-01-31 | 2001-08-14 | Gerald S. Brenner | Pharmaceutical compositions containing insoluble salts of bisphosphonic acids |
GB9009548D0 (en) | 1990-04-27 | 1990-06-20 | Celltech Ltd | Chimeric antibody and method |
JPH04228089A (ja) | 1990-05-15 | 1992-08-18 | Kanegafuchi Chem Ind Co Ltd | 高カルシウム血症治療・予防剤 |
WO1992000753A1 (en) | 1990-07-13 | 1992-01-23 | The Regents Of The University Of California | PARATHYROID HORMONE ANALOGUES MODIFIED AT POSITIONS 3, 6 or 9 |
ES2108048T3 (es) | 1990-08-29 | 1997-12-16 | Genpharm Int | Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos. |
DE69233472T2 (de) | 1991-04-05 | 2006-02-09 | The General Hospital Corp., Charlestown | Parathormonrezeptor und dafür codierende DNA |
EP0628639B1 (de) | 1991-04-25 | 1999-06-23 | Chugai Seiyaku Kabushiki Kaisha | Rekombinierte humane antikörper gegen den humanen interleukin 6-rezeptor |
EP0746609A4 (de) | 1991-12-17 | 1997-12-17 | Genpharm Int | Heterologe antikörper produzierende transgene nicht-humane tiere |
AU3095892A (en) | 1991-12-20 | 1993-07-28 | Protein Design Labs, Inc. | Human type antibody reactive with GPIIb/IIIa |
WO1994002602A1 (en) | 1992-07-24 | 1994-02-03 | Cell Genesys, Inc. | Generation of xenogeneic antibodies |
US5648267A (en) | 1992-11-13 | 1997-07-15 | Idec Pharmaceuticals Corporation | Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same |
US5849695A (en) | 1993-01-13 | 1998-12-15 | The Regents Of The University Of California | Parathyroid hormone analogues useful for treatment of osteoporosis and disorders of calcium meatabolism in mammals |
AU6819494A (en) | 1993-04-26 | 1994-11-21 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
JP3504697B2 (ja) | 1993-09-30 | 2004-03-08 | 株式会社先端生命科学研究所 | PTHrPアンタゴニスト活性を有するポリペプチド及びそれを含むカルシウム代謝治療薬 |
JPH07316195A (ja) | 1994-05-25 | 1995-12-05 | Nippon Kayaku Co Ltd | 新規なPTHrP関連ペプチド及びその用途 |
CA2194907A1 (en) | 1994-07-13 | 1996-02-01 | Kouji Matsushima | Reshaped human antibody against human interleukin-8 |
CO4410206A1 (es) | 1994-07-28 | 1997-01-09 | Sandoz Ag | DERIVADOS DE PTH o PTHrP, SU PREPARACION Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
US5993817A (en) | 1995-01-23 | 1999-11-30 | Xenotech | Method to ameliorate osteolysis and metastasis |
EP0813423B1 (de) | 1995-01-23 | 2002-07-03 | Xenotech Incorporated | Zusammensetzung zur verhinderung von osteolyse und metastasen |
US5626845A (en) | 1995-01-23 | 1997-05-06 | Xenotech Incorporated | Method to ameliorate osteolysis and metastasis |
EP0811383B1 (de) | 1995-02-20 | 2007-05-30 | Yukio Kato | Heilmittel für arthrosis deformans und entzündliche gelenkerkrankungen |
DE69610826T2 (de) | 1995-03-01 | 2001-05-03 | Stryker Corp | Morphogeninduzierte regenerierung der dentin |
AU5632296A (en) | 1995-04-27 | 1996-11-18 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
US5660826A (en) | 1995-06-06 | 1997-08-26 | The Regents Of The University Of California | Therapeutic sepsis treatment using antagonists to PTHrP |
WO1997027870A1 (fr) | 1996-02-01 | 1997-08-07 | Chugai Seiyaku Kabushiki Kaisha | Medicaments prevenant ou guerissant la thrombopenie |
WO1998011218A1 (en) | 1996-09-10 | 1998-03-19 | Theodor-Kocher Institute | Cxcr3 chemokine receptor, antibodies, nucleic acids, and methods of use |
BR9713294A (pt) | 1996-09-26 | 2000-10-17 | Chugai Pharmaceutical Co Ltd | "anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano" |
JP4372240B2 (ja) | 1997-05-15 | 2009-11-25 | 中外製薬株式会社 | 悪液質治療剤 |
BR9809629A (pt) * | 1997-05-15 | 2000-07-04 | Chugai Pharmaceutical Co Ltd | Agente terapêutico para caquexia |
JP4414494B2 (ja) | 1998-02-03 | 2010-02-10 | 旭化成ファーマ株式会社 | 白血球減少症の予防剤および治療剤 |
CA2327509A1 (en) | 1998-05-05 | 1999-11-11 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R | Pth2 receptor selective compounds |
JP2000080100A (ja) * | 1998-06-17 | 2000-03-21 | Japan Tobacco Inc | 副甲状腺ホルモン関連タンパクに対するヒトモノクローナル抗体 |
CZ20004753A3 (cs) | 1998-06-26 | 2002-06-12 | Chugai Seiyaku Kabushiki Kaisha | Terapeutické činidlo na hyperkalcinemickou krizi |
JP2000131793A (ja) | 1998-10-27 | 2000-05-12 | Konica Corp | 熱現像感光材料の製造方法、これにより製造した熱現像感光材料を用いた画像記録方法及び画像形成方法 |
JP2000173834A (ja) | 1998-12-10 | 2000-06-23 | Mitsubishi Electric Corp | シート巻静止誘導電器 |
-
2001
- 2001-04-26 EP EP01925993A patent/EP1283057B2/de not_active Expired - Lifetime
- 2001-04-26 EP EP08009290A patent/EP1987842A1/de not_active Withdrawn
- 2001-04-26 AU AU2001252618A patent/AU2001252618A1/en not_active Abandoned
- 2001-04-26 WO PCT/JP2001/003665 patent/WO2001082968A1/ja active Application Filing
- 2001-04-26 JP JP2001579841A patent/JP4846169B2/ja not_active Expired - Fee Related
- 2001-04-26 DE DE60137417T patent/DE60137417D1/de not_active Expired - Lifetime
- 2001-04-26 AT AT01925993T patent/ATE420661T1/de not_active IP Right Cessation
- 2001-04-26 US US10/258,477 patent/US8029793B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP1283057A1 (de) | 2003-02-12 |
ATE420661T1 (de) | 2009-01-15 |
EP1283057B1 (de) | 2009-01-14 |
EP1987842A1 (de) | 2008-11-05 |
AU2001252618A1 (en) | 2001-11-12 |
US20040001824A1 (en) | 2004-01-01 |
US8029793B2 (en) | 2011-10-04 |
JP4846169B2 (ja) | 2011-12-28 |
EP1283057B2 (de) | 2012-05-30 |
WO2001082968A1 (fr) | 2001-11-08 |
EP1283057A4 (de) | 2005-08-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |