FI943513A - Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja - Google Patents

Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja Download PDF

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Publication number
FI943513A
FI943513A FI943513A FI943513A FI943513A FI 943513 A FI943513 A FI 943513A FI 943513 A FI943513 A FI 943513A FI 943513 A FI943513 A FI 943513A FI 943513 A FI943513 A FI 943513A
Authority
FI
Finland
Prior art keywords
ones
phenylureidoazepin
benzazepin
useful
cholecystokinin antagonists
Prior art date
Application number
FI943513A
Other languages
English (en)
Swedish (sv)
Other versions
FI943513A0 (fi
Inventor
Iii John A Lowe
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI943513A publication Critical patent/FI943513A/fi
Publication of FI943513A0 publication Critical patent/FI943513A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI943513A 1992-01-27 1994-07-26 Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja FI943513A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82567792A 1992-01-27 1992-01-27
PCT/US1992/010720 WO1993015059A1 (en) 1992-01-27 1992-12-16 3-phenylureido-azepin-2-ones and -benzazepin-2-ones useful as cholecystokinin antagonists

Publications (2)

Publication Number Publication Date
FI943513A true FI943513A (fi) 1994-07-26
FI943513A0 FI943513A0 (fi) 1994-07-26

Family

ID=25244657

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943513A FI943513A0 (fi) 1992-01-27 1994-07-26 Kolekystokiniiniantagonisteina käyttökelpoisia 3-fenyyliureidoatsepin-2-oneja ja -bentsatsepin-2-oneja

Country Status (19)

Country Link
EP (1) EP0625145A1 (fi)
JP (1) JPH07503465A (fi)
KR (1) KR950700257A (fi)
CN (1) CN1074903A (fi)
AU (1) AU3276193A (fi)
BR (1) BR9207071A (fi)
CA (1) CA2117367A1 (fi)
CZ (1) CZ391092A3 (fi)
FI (1) FI943513A0 (fi)
HU (1) HUT70496A (fi)
IL (1) IL104472A0 (fi)
MX (1) MX9300409A (fi)
NO (1) NO942775L (fi)
NZ (1) NZ245759A (fi)
RU (1) RU94038063A (fi)
TW (1) TW213901B (fi)
WO (1) WO1993015059A1 (fi)
YU (1) YU4393A (fi)
ZA (1) ZA93582B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2097688A1 (es) * 1993-07-14 1997-04-01 Pfizer Hexahidroazepinonas y tetrahidrobenzazepinonas sustituidas.
ES2132401T3 (es) * 1993-07-26 1999-08-16 Pfizer Tetrahidro-1h-benzazepinonas y hexahidroazepinonas como antagonistas selectivos del receptor colecistoquinina-b.
US5453424A (en) * 1993-11-22 1995-09-26 Merck & Co., Inc. Furanodiazepines
AU681924B2 (en) * 1993-11-22 1997-09-11 Merck & Co., Inc. 3-acylaminobenzazepines
WO1996010564A1 (en) * 1994-10-04 1996-04-11 Pfizer Inc. Processes and intermediates for preparing 3-amino-benzo(b)azepinones
WO1996011689A1 (en) * 1994-10-14 1996-04-25 Glaxo Wellcome Spa Use of cck-b receptor antagonists for the treatment of sleep disorders
DE10153348A1 (de) * 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0166357A3 (en) * 1984-06-26 1988-10-26 Merck & Co. Inc. Benzofused lactams and pharmaceutical compositions containing them
US4767756A (en) * 1987-07-17 1988-08-30 E. R. Squibb & Sons, Inc. 3-substituted benzazepines
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck

Also Published As

Publication number Publication date
HU9402195D0 (en) 1994-09-28
AU3276193A (en) 1993-09-01
WO1993015059A1 (en) 1993-08-05
CN1074903A (zh) 1993-08-04
ZA93582B (en) 1994-07-27
BR9207071A (pt) 1995-12-05
CZ391092A3 (en) 1994-01-19
EP0625145A1 (en) 1994-11-23
NZ245759A (en) 1997-06-24
FI943513A0 (fi) 1994-07-26
HUT70496A (en) 1995-10-30
NO942775L (no) 1994-09-20
IL104472A0 (en) 1993-05-13
JPH07503465A (ja) 1995-04-13
NO942775D0 (no) 1994-07-26
CA2117367A1 (en) 1993-08-05
KR950700257A (ko) 1995-01-16
MX9300409A (es) 1993-07-01
YU4393A (sr) 1996-01-09
RU94038063A (ru) 1996-05-27
TW213901B (fi) 1993-10-01

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