ES2132401T3 - Tetrahidro-1h-benzazepinonas y hexahidroazepinonas como antagonistas selectivos del receptor colecistoquinina-b. - Google Patents
Tetrahidro-1h-benzazepinonas y hexahidroazepinonas como antagonistas selectivos del receptor colecistoquinina-b.Info
- Publication number
- ES2132401T3 ES2132401T3 ES94914525T ES94914525T ES2132401T3 ES 2132401 T3 ES2132401 T3 ES 2132401T3 ES 94914525 T ES94914525 T ES 94914525T ES 94914525 T ES94914525 T ES 94914525T ES 2132401 T3 ES2132401 T3 ES 2132401T3
- Authority
- ES
- Spain
- Prior art keywords
- pct
- receptor
- hexahidroazepinonas
- collectostokinin
- benzazepinonas
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
LA INVENCION SE REFIERE A COMPUESTOS DE FORMULA (I) EN LA QUE R{SUP,1}, R{SUP,2}, R{SUP,3} Y R{SUP,4} Y X SON COMO DEFINIDAS EN LA APLICACION. ESTOS COMPUESTOS SON ANTAGONISTAS RECEPTORES DE CCK-B UTILES EN EL TRATAMIENTO Y PREVENCION DE DESORDENES GASTROINTESTINALES Y DEL SISTEMA NERVIOSO CENTRAL.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9764093A | 1993-07-26 | 1993-07-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2132401T3 true ES2132401T3 (es) | 1999-08-16 |
Family
ID=22264420
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94914525T Expired - Lifetime ES2132401T3 (es) | 1993-07-26 | 1994-05-19 | Tetrahidro-1h-benzazepinonas y hexahidroazepinonas como antagonistas selectivos del receptor colecistoquinina-b. |
Country Status (13)
Country | Link |
---|---|
US (1) | US5618811A (es) |
EP (1) | EP0711283B1 (es) |
JP (1) | JP2862675B2 (es) |
AT (1) | ATE181323T1 (es) |
AU (1) | AU6686694A (es) |
CA (1) | CA2168131C (es) |
DE (1) | DE69419157T2 (es) |
DK (1) | DK0711283T3 (es) |
ES (1) | ES2132401T3 (es) |
FI (4) | FI943499A (es) |
GR (1) | GR3030816T3 (es) |
IL (1) | IL110349A0 (es) |
WO (1) | WO1995003281A1 (es) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6369080B2 (en) | 1996-10-11 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6262047B1 (en) | 1996-10-11 | 2001-07-17 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6063794A (en) | 1996-10-11 | 2000-05-16 | Cor Therapeutics Inc. | Selective factor Xa inhibitors |
US6194435B1 (en) | 1996-10-11 | 2001-02-27 | Cor Therapeutics, Inc. | Lactams as selective factor Xa inhibitors |
US6369063B1 (en) | 1997-04-14 | 2002-04-09 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
EP0975625A1 (en) | 1997-04-14 | 2000-02-02 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
WO1998046626A1 (en) | 1997-04-14 | 1998-10-22 | Cor Therapeutics, Inc. | SELECTIVE FACTOR Xa INHIBITORS |
US6333321B1 (en) | 1997-08-11 | 2001-12-25 | Cor Therapeutics, Inc. | Selective factor Xa inhibitors |
US6218382B1 (en) | 1997-08-11 | 2001-04-17 | Cor Therapeutics, Inc | Selective factor Xa inhibitors |
US6344450B1 (en) | 1999-02-09 | 2002-02-05 | Bristol-Myers Squibb Company | Lactam compounds and their use as inhibitors of serine proteases and method |
CA2360305A1 (en) * | 1999-02-09 | 2000-08-17 | Bristol-Myers Squibb Company | Lactam inhibitors of fxa and method |
US6319915B1 (en) * | 1999-08-27 | 2001-11-20 | Pfizer Inc. | Benzazepine derivatives as inhibitors of hyperproliferation diseases |
US6511973B2 (en) | 2000-08-02 | 2003-01-28 | Bristol-Myers Squibb Co. | Lactam inhibitors of FXa and method |
JP5197361B2 (ja) * | 2005-06-06 | 2013-05-15 | ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ | 睡眠障害を処置するための組成物および方法 |
UA105182C2 (ru) | 2008-07-03 | 2014-04-25 | Ньюрексон, Інк. | Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04210967A (ja) * | 1989-12-28 | 1992-08-03 | Yoshitomi Pharmaceut Ind Ltd | 2−ベンズアゼピン化合物 |
US5206234A (en) * | 1990-10-22 | 1993-04-27 | Merck & Co., Inc. | Benzolactam analogs as antagonists of cck |
TW213901B (es) * | 1992-01-27 | 1993-10-01 | Pfizer |
-
1994
- 1994-05-19 EP EP94914525A patent/EP0711283B1/en not_active Expired - Lifetime
- 1994-05-19 DK DK94914525T patent/DK0711283T3/da active
- 1994-05-19 CA CA002168131A patent/CA2168131C/en not_active Expired - Fee Related
- 1994-05-19 AU AU66866/94A patent/AU6686694A/en not_active Abandoned
- 1994-05-19 JP JP7505034A patent/JP2862675B2/ja not_active Expired - Lifetime
- 1994-05-19 AT AT94914525T patent/ATE181323T1/de not_active IP Right Cessation
- 1994-05-19 US US08/586,685 patent/US5618811A/en not_active Expired - Fee Related
- 1994-05-19 WO PCT/IB1994/000111 patent/WO1995003281A1/en active IP Right Grant
- 1994-05-19 ES ES94914525T patent/ES2132401T3/es not_active Expired - Lifetime
- 1994-05-19 DE DE69419157T patent/DE69419157T2/de not_active Expired - Fee Related
- 1994-07-18 IL IL11034994A patent/IL110349A0/xx unknown
- 1994-07-25 FI FI943499A patent/FI943499A/fi unknown
-
1999
- 1999-07-20 GR GR990401904T patent/GR3030816T3/el unknown
- 1999-09-23 FI FI992037A patent/FI19992037A/fi unknown
- 1999-09-23 FI FI992038A patent/FI19992038A/fi unknown
- 1999-09-23 FI FI992039A patent/FI19992039A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
US5618811A (en) | 1997-04-08 |
GR3030816T3 (en) | 1999-11-30 |
DE69419157T2 (de) | 1999-10-14 |
IL110349A0 (en) | 1994-10-21 |
EP0711283B1 (en) | 1999-06-16 |
EP0711283A1 (en) | 1996-05-15 |
CA2168131C (en) | 1998-10-06 |
FI19992038A (fi) | 1999-09-23 |
DK0711283T3 (da) | 1999-11-22 |
JP2862675B2 (ja) | 1999-03-03 |
JPH08508039A (ja) | 1996-08-27 |
FI943499A0 (fi) | 1994-07-25 |
DE69419157D1 (de) | 1999-07-22 |
CA2168131A1 (en) | 1995-02-02 |
WO1995003281A1 (en) | 1995-02-02 |
FI19992037A (fi) | 1999-09-23 |
FI19992039A (fi) | 1999-09-23 |
FI943499A (fi) | 1995-01-27 |
ATE181323T1 (de) | 1999-07-15 |
AU6686694A (en) | 1995-02-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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