GR3030816T3 - Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists - Google Patents

Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists

Info

Publication number
GR3030816T3
GR3030816T3 GR990401904T GR990401904T GR3030816T3 GR 3030816 T3 GR3030816 T3 GR 3030816T3 GR 990401904 T GR990401904 T GR 990401904T GR 990401904 T GR990401904 T GR 990401904T GR 3030816 T3 GR3030816 T3 GR 3030816T3
Authority
GR
Greece
Prior art keywords
receptor antagonists
pct
hexahydroazepinones
benzazepinones
tetrahydro
Prior art date
Application number
GR990401904T
Other languages
English (en)
Inventor
John A Lowe Iii
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3030816T3 publication Critical patent/GR3030816T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
GR990401904T 1993-07-26 1999-07-20 Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists GR3030816T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9764093A 1993-07-26 1993-07-26
PCT/IB1994/000111 WO1995003281A1 (en) 1993-07-26 1994-05-19 Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists

Publications (1)

Publication Number Publication Date
GR3030816T3 true GR3030816T3 (en) 1999-11-30

Family

ID=22264420

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990401904T GR3030816T3 (en) 1993-07-26 1999-07-20 Tetrahydro-1h-benzazepinones and hexahydroazepinones as selective cholecystokinin-b receptor antagonists

Country Status (13)

Country Link
US (1) US5618811A (el)
EP (1) EP0711283B1 (el)
JP (1) JP2862675B2 (el)
AT (1) ATE181323T1 (el)
AU (1) AU6686694A (el)
CA (1) CA2168131C (el)
DE (1) DE69419157T2 (el)
DK (1) DK0711283T3 (el)
ES (1) ES2132401T3 (el)
FI (4) FI943499A (el)
GR (1) GR3030816T3 (el)
IL (1) IL110349A0 (el)
WO (1) WO1995003281A1 (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
EP0975625A1 (en) 1997-04-14 2000-02-02 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
JP2001523226A (ja) 1997-04-14 2001-11-20 シーオーアール セラピューティクス インコーポレイテッド 選択的Xa因子阻害剤
WO1998046627A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6333321B1 (en) 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
EP1156803A4 (en) * 1999-02-09 2004-03-17 Bristol Myers Squibb Co FXA LACTAM INHIBITORS AND METHOD
US6344450B1 (en) 1999-02-09 2002-02-05 Bristol-Myers Squibb Company Lactam compounds and their use as inhibitors of serine proteases and method
US6319915B1 (en) * 1999-08-27 2001-11-20 Pfizer Inc. Benzazepine derivatives as inhibitors of hyperproliferation diseases
US6511973B2 (en) 2000-08-02 2003-01-28 Bristol-Myers Squibb Co. Lactam inhibitors of FXa and method
ES2423412T3 (es) * 2005-06-06 2013-09-20 The Board Of Trustees Of The University Of Illinois Composiciones y métodos para tratar los trastornos del sueño
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04210967A (ja) * 1989-12-28 1992-08-03 Yoshitomi Pharmaceut Ind Ltd 2−ベンズアゼピン化合物
US5206234A (en) * 1990-10-22 1993-04-27 Merck & Co., Inc. Benzolactam analogs as antagonists of cck
TW213901B (el) * 1992-01-27 1993-10-01 Pfizer

Also Published As

Publication number Publication date
CA2168131A1 (en) 1995-02-02
CA2168131C (en) 1998-10-06
EP0711283A1 (en) 1996-05-15
US5618811A (en) 1997-04-08
EP0711283B1 (en) 1999-06-16
FI19992037A (fi) 1999-09-23
WO1995003281A1 (en) 1995-02-02
JP2862675B2 (ja) 1999-03-03
ES2132401T3 (es) 1999-08-16
FI943499A0 (fi) 1994-07-25
FI19992038A (fi) 1999-09-23
DK0711283T3 (da) 1999-11-22
DE69419157D1 (de) 1999-07-22
ATE181323T1 (de) 1999-07-15
DE69419157T2 (de) 1999-10-14
FI943499A (fi) 1995-01-27
AU6686694A (en) 1995-02-20
IL110349A0 (en) 1994-10-21
JPH08508039A (ja) 1996-08-27
FI19992039A (fi) 1999-09-23

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