NO962717D0 - Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister - Google Patents

Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister

Info

Publication number
NO962717D0
NO962717D0 NO962717A NO962717A NO962717D0 NO 962717 D0 NO962717 D0 NO 962717D0 NO 962717 A NO962717 A NO 962717A NO 962717 A NO962717 A NO 962717A NO 962717 D0 NO962717 D0 NO 962717D0
Authority
NO
Norway
Prior art keywords
diaryl
fused heterocyclic
leukotriene antagonists
heterocyclic acids
acids
Prior art date
Application number
NO962717A
Other languages
English (en)
Other versions
NO962717L (no
Inventor
Robert N Young
Marc Labelle
Yves Leblanc
Cheuk K Lau
Claude Dufresne
Yves Gareau
Yi Bin Xiang
Original Assignee
Merck Frosst Canada Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Frosst Canada Inc filed Critical Merck Frosst Canada Inc
Publication of NO962717D0 publication Critical patent/NO962717D0/no
Publication of NO962717L publication Critical patent/NO962717L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO962717A 1993-12-28 1996-06-27 Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister NO962717L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17493793A 1993-12-28 1993-12-28
US08/260,592 US5472964A (en) 1992-12-22 1994-06-16 Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists
PCT/CA1994/000716 WO1995018132A1 (en) 1993-12-28 1994-12-22 Diaryl 5,6-fused heterocyclic acids as leukotriene antagonists

Publications (2)

Publication Number Publication Date
NO962717D0 true NO962717D0 (no) 1996-06-27
NO962717L NO962717L (no) 1996-06-27

Family

ID=26870689

Family Applications (1)

Application Number Title Priority Date Filing Date
NO962717A NO962717L (no) 1993-12-28 1996-06-27 Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister

Country Status (12)

Country Link
US (1) US5472964A (no)
EP (1) EP0737196A1 (no)
JP (1) JP3594603B2 (no)
CN (1) CN1148389A (no)
AU (1) AU684884B2 (no)
CA (1) CA2180014A1 (no)
CZ (1) CZ187996A3 (no)
FI (1) FI962639A0 (no)
HU (1) HUT76544A (no)
NO (1) NO962717L (no)
SK (1) SK83896A3 (no)
WO (1) WO1995018132A1 (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5656638A (en) * 1995-04-18 1997-08-12 Geron Corporation Telomerase inhibitors
EP1014972A4 (en) * 1996-02-08 2004-12-08 Merck & Co Inc TREATMENT METHOD AND PHARMACEUTICAL COMPOSITION
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
EP1321169A1 (en) * 2001-12-18 2003-06-25 Biofrontera Pharmaceuticals AG Combination of a serotonin receptor antagonist with a histidine decarboxylase inhibitor as a medicament
CA2371048C (en) 2002-02-06 2011-01-04 Delmar Chemicals Inc. Process for the preparation of 1-(mercaptomethyl)-cyclopropaneacetic acid
EP1819329A2 (en) * 2004-08-04 2007-08-22 Schering Corporation Pharmaceutical formulations comprising pleconaril for the treatment of airway diseases
WO2006047427A1 (en) 2004-10-25 2006-05-04 Schering Corporation M1 and/or m3 receptor antagonists in combination with other actives for treating respiratory disorders
US20090099367A1 (en) * 2006-03-06 2009-04-16 Farmaprojects, S. A. Process for preparing a leukotriene antagonist
US7919505B2 (en) * 2006-07-11 2011-04-05 Schering Corporation Xinafoate salt of a substituted 5-oxazol-2-yl-quinoline compound
EP2265586A4 (en) * 2008-03-17 2012-10-03 Reddys Lab Ltd Dr PREPARATION OF MONTELUKAST AND ITS SALTS
EP2268646B9 (en) * 2008-04-11 2014-11-19 Janssen Pharmaceutica, N.V. Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene a4 hydrolase
US9532717B2 (en) * 2008-10-28 2017-01-03 The Procter & Gamble Company Method for diagnosing vulvovaginal disorders
JP2012530140A (ja) 2009-06-16 2012-11-29 メルク・シャープ・アンド・ドーム・コーポレーション グルココルチコイド受容体アゴニストとしての新規［３，２−ｃ］ヘテロアリールステロイド、組成物およびこの使用
CN110386888A (zh) * 2019-07-30 2019-10-29 上海红蓝医药科技有限公司 一种低成本、高收率的1-(巯甲基)环丙基乙酸生产工艺
WO2023218023A1 (en) 2022-05-13 2023-11-16 Idorsia Pharmaceuticals Ltd Thiazoloaryl-methyl substituted cyclic hydrazine-n-carboxamide derivatives

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4794188A (en) * 1982-12-01 1988-12-27 Usv Pharmaceutical Corporation Certain unsymmetrical quinolinyl ethers having anti-inflammatory and anti-allergic activity
US4957932A (en) * 1987-11-25 1990-09-18 Merck Frosst Canada, Inc. Benzoheterazoles
US5026698A (en) * 1988-11-02 1991-06-25 Nissan Chemical Industries, Ltd. Thienopyridine type mevalonolactones
EP0480716A1 (en) * 1990-10-12 1992-04-15 Merck Frosst Canada Inc. Saturated hydroxyalkylquinoline acids as leukotriene antagonists
HU222344B1 (hu) * 1990-10-12 2003-06-28 Merck Frosst Canada & Co. Eljárás telítetlen hidroxi-alkil-kinolinsavak, és ezeket tartalmazó gyógyszerkészítmények előállítására
US5308850A (en) * 1991-09-30 1994-05-03 Merck Frosst Canada, Inc. (Bicyclic-hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5506227A (en) * 1992-04-13 1996-04-09 Merck Frosst Canada, Inc. Pyridine-substituted benzyl alcohols as leukotriene antagonists
CA2111372C (en) * 1992-12-22 2007-01-16 Robert N. Young Diaryl 5,6-fusedheterocyclic acids as leukotriene antagonists

Also Published As

Publication number Publication date
SK83896A3 (en) 1997-02-05
JP3594603B2 (ja) 2004-12-02
HUT76544A (en) 1997-09-29
CA2180014A1 (en) 1995-07-06
AU1378195A (en) 1995-07-17
EP0737196A1 (en) 1996-10-16
US5472964A (en) 1995-12-05
CZ187996A3 (en) 1997-01-15
FI962639A (fi) 1996-06-26
JPH09507080A (ja) 1997-07-15
NO962717L (no) 1996-06-27
WO1995018132A1 (en) 1995-07-06
HU9601772D0 (en) 1996-09-30
AU684884B2 (en) 1998-01-08
FI962639A0 (fi) 1996-06-26
CN1148389A (zh) 1997-04-23

Similar Documents

Publication Publication Date Title
NO965036D0 (no) Kinolinderivater som techykinin NK3 reseptor-antagonister
DE59501802D1 (de) Substituierte 1H-3-Aryl-pyrrolidin-2,4-dion-Derivate
DE69431604D1 (de) Benzofuranderivate als tachykininantagonisten
DK0393936T3 (da) 3-substituerede 2-oxindolderivater som antiinflammatoriske midler
BR9711970A (pt) Derivados 6,5-substitu¡do-heterobic¡clicos
NL300035I2 (nl) Gesubstitueerde thiazolidinedionderivaten.
DK1000048T3 (da) Substituerede 1,2,3,4-tetrahydronapthalenderivater
NO962717D0 (no) Diaryl-5,6-kondenserte, heterosykliske syrer som leukotrienantagonister
FI961628A (fi) Indolijohdannaisia NMDA-antagonisteina
NO991384D0 (no) Substituerte heterocykler som anti-tumormidler
DK0922034T3 (da) Tetrahydroquinolinderivater som EAA-antagonister
NO903863D0 (no) Tiazolidindionderivater som hypoglykemiske midler.
ATE212635T1 (de) 1,3,8-triazaspiro(4,5)decan-4-on-derivate
NO20021251D0 (no) Tienoisoksazolyl- og tienylpyrrazolyl-fenoksysubstituerte propylderivater anvendelige som D4antagonister
FI972684A0 (fi) Piperidiinietikkahappojohdannaisia, joita voidaan käyttää fibrinogeeniantagonisteina
DK0964863T3 (da) Oxazolidinoner som 5-HT2A-antagonister
DE68923913D1 (de) Neplanocinderivate.
FI951798A0 (fi) Bentsofuraanijohdannaiset 5-HT1-kaltaisina reseptoriantagonisteina
NO961333D0 (no) Nye pyrazolderivater som angiotensin-II-antagonister
NO992066D0 (no) Piperazinoderivater som neurokininantagonister
DE59707423D1 (de) Pyrazol-4-yl-hetaroylderivate als herbizide
NO950684L (no) Nye imidazopyridinderivater som angiotensin II-antagonister
NO996244D0 (no) Pyrrolidinkarboksylsyrederivater som endotelinantagonister
AU7379794A (en) Aza-5,5-fused heterocyclic acids as leukotriene antagonists
DK0944601T3 (da) Heterocykliske quanidinylaminoforbindelser som alfa-2-adrenoceptoragonister