CN1230185A - 双环芳杂环化合物用作蛋白质酪氨酸激酶的抑制剂 - Google Patents
双环芳杂环化合物用作蛋白质酪氨酸激酶的抑制剂 Download PDFInfo
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- CN1230185A CN1230185A CN97197787A CN97197787A CN1230185A CN 1230185 A CN1230185 A CN 1230185A CN 97197787 A CN97197787 A CN 97197787A CN 97197787 A CN97197787 A CN 97197787A CN 1230185 A CN1230185 A CN 1230185A
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- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 claims abstract description 11
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/78—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C217/80—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
- C07C217/82—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
- C07C217/84—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
- C07C217/86—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
- C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9614756.6 | 1996-07-13 | ||
| GBGB9614756.6A GB9614756D0 (en) | 1996-07-13 | 1996-07-13 | Heterocyclic compounds |
| GB9625495.8 | 1996-12-07 | ||
| GBGB9625495.8A GB9625495D0 (en) | 1996-12-07 | 1996-12-07 | Heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1230185A true CN1230185A (zh) | 1999-09-29 |
Family
ID=26309691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN97197787A Pending CN1230185A (zh) | 1996-07-13 | 1997-07-11 | 双环芳杂环化合物用作蛋白质酪氨酸激酶的抑制剂 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6207669B1 (enExample) |
| EP (1) | EP0912572B1 (enExample) |
| JP (1) | JP2000515136A (enExample) |
| KR (1) | KR20000023813A (enExample) |
| CN (1) | CN1230185A (enExample) |
| AP (1) | AP9901435A0 (enExample) |
| AR (1) | AR007855A1 (enExample) |
| AT (1) | ATE231148T1 (enExample) |
| AU (1) | AU3693697A (enExample) |
| BR (1) | BR9710362A (enExample) |
| CA (1) | CA2260058A1 (enExample) |
| CZ (1) | CZ8799A3 (enExample) |
| DE (1) | DE69718472T2 (enExample) |
| EA (1) | EA199900021A1 (enExample) |
| ES (1) | ES2191187T3 (enExample) |
| ID (1) | ID19430A (enExample) |
| IS (1) | IS4936A (enExample) |
| NO (1) | NO990123L (enExample) |
| PE (1) | PE91098A1 (enExample) |
| PL (1) | PL331154A1 (enExample) |
| TR (1) | TR199900048T2 (enExample) |
| WO (1) | WO1998002437A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101735200B (zh) * | 2008-11-17 | 2013-01-02 | 岑均达 | 喹唑啉类化合物 |
| CN102264745B (zh) * | 2008-11-10 | 2015-07-22 | 财团法人卫生研究院 | 作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 |
Families Citing this family (260)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997030035A1 (en) | 1996-02-13 | 1997-08-21 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
| PT885198E (pt) | 1996-03-05 | 2002-06-28 | Astrazeneca Ab | Derivados de 4-anilinoquinazolina |
| HRP970371A2 (en) | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
| HUP0100287A3 (en) | 1997-11-11 | 2003-04-28 | Pfizer Prod Inc | Thienopyrimidine and thienopyridine derivatives useful as anticancer agents |
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| NO744352L (enExample) * | 1973-12-12 | 1975-07-07 | Takeda Chemical Industries Ltd | |
| US4166735A (en) * | 1977-01-21 | 1979-09-04 | Shell Oil Company | Cycloalkanecarboxanilide derivative herbicides |
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- 1997-07-11 BR BR9710362A patent/BR9710362A/pt not_active Application Discontinuation
- 1997-07-11 WO PCT/EP1997/003673 patent/WO1998002437A1/en not_active Ceased
- 1997-07-11 CN CN97197787A patent/CN1230185A/zh active Pending
- 1997-07-11 AU AU36936/97A patent/AU3693697A/en not_active Abandoned
- 1997-07-11 EP EP97933661A patent/EP0912572B1/en not_active Expired - Lifetime
- 1997-07-11 US US09/214,261 patent/US6207669B1/en not_active Expired - Fee Related
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- 1997-07-11 CZ CZ9987A patent/CZ8799A3/cs unknown
- 1997-07-11 AR ARP970103101A patent/AR007855A1/es unknown
- 1997-07-11 AP APAP/P/1999/001435A patent/AP9901435A0/en unknown
- 1997-07-11 CA CA002260058A patent/CA2260058A1/en not_active Abandoned
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1998
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1999
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- 1999-01-13 KR KR1019997000299A patent/KR20000023813A/ko not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102264745B (zh) * | 2008-11-10 | 2015-07-22 | 财团法人卫生研究院 | 作为酪胺酸激酶抑制剂的稠合双环及多环嘧啶化合物 |
| CN101735200B (zh) * | 2008-11-17 | 2013-01-02 | 岑均达 | 喹唑啉类化合物 |
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| CZ8799A3 (cs) | 1999-06-16 |
| ES2191187T3 (es) | 2003-09-01 |
| EP0912572B1 (en) | 2003-01-15 |
| AU3693697A (en) | 1998-02-09 |
| JP2000515136A (ja) | 2000-11-14 |
| ID19430A (id) | 1998-07-09 |
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| US6207669B1 (en) | 2001-03-27 |
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| EA199900021A1 (ru) | 1999-08-26 |
| WO1998002437A1 (en) | 1998-01-22 |
| CA2260058A1 (en) | 1998-01-22 |
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| AR007855A1 (es) | 1999-11-24 |
| DE69718472D1 (de) | 2003-02-20 |
| DE69718472T2 (de) | 2003-11-06 |
| IS4936A (is) | 1998-12-29 |
| NO990123D0 (no) | 1999-01-12 |
| KR20000023813A (en) | 2000-04-25 |
| BR9710362A (pt) | 1999-08-17 |
| TR199900048T2 (xx) | 1999-04-21 |
| ATE231148T1 (de) | 2003-02-15 |
| PE91098A1 (es) | 1999-01-15 |
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