CN118724806A - 氘化化合物和其用途 - Google Patents
氘化化合物和其用途 Download PDFInfo
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- CN118724806A CN118724806A CN202410737001.8A CN202410737001A CN118724806A CN 118724806 A CN118724806 A CN 118724806A CN 202410737001 A CN202410737001 A CN 202410737001A CN 118724806 A CN118724806 A CN 118724806A
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- deuterium
- compound
- hydrogen peroxide
- treatment
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Landscapes
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| US201562208223P | 2015-08-21 | 2015-08-21 | |
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| PCT/US2016/048054 WO2017035077A1 (en) | 2015-08-21 | 2016-08-22 | Deuterated compounds and uses thereof |
| CN201680059219.6A CN108135907A (zh) | 2015-08-21 | 2016-08-22 | 氘化化合物和其用途 |
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| PT1888548E (pt) | 2005-05-26 | 2012-10-30 | Neuron Systems Inc | Derivado de quinolina para o tratamento de doenças da retina |
| WO2011072141A1 (en) | 2009-12-11 | 2011-06-16 | Neuron Systems, Inc. | Compositions and methods for the treatment of macular degeneration |
| CA2898631C (en) | 2013-01-23 | 2023-06-13 | Aldeyra Therapeutics, Inc. | Toxic aldehyde related diseases and treatment |
| CN118724806A (zh) | 2015-08-21 | 2024-10-01 | 奥尔德拉医疗公司 | 氘化化合物和其用途 |
| CA3016759A1 (en) | 2016-02-28 | 2017-08-31 | Aldeyra Therapeutics, Inc. | Treatment of allergic eye conditions with cyclodextrins |
| US11129823B2 (en) | 2016-05-09 | 2021-09-28 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
| JP2019532029A (ja) * | 2016-08-22 | 2019-11-07 | アルデイラ セラピューティクス， インコーポレイテッド | アルデヒド補足化合物およびその使用 |
| AU2017317529A1 (en) * | 2016-08-22 | 2019-02-21 | Aldeyra Therapeutics, Inc. | Aldehyde trapping compounds and methods of use thereof |
| MX2019010576A (es) | 2017-03-16 | 2019-10-07 | Aldeyra Therapeutics Inc | Compuestos polimorficos y usos de los mismos. |
| JP7311162B2 (ja) | 2017-10-10 | 2023-07-19 | アルデイラ セラピューティクス， インコーポレイテッド | 炎症性障害の処置 |
| WO2020028820A1 (en) | 2018-08-03 | 2020-02-06 | Aldeyra Therapeutics, Inc. | Topical compositions and methods of preparation and use |
| WO2020033344A1 (en) | 2018-08-06 | 2020-02-13 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
| EP3856478A4 (en) | 2018-09-25 | 2022-06-08 | Aldeyra Therapeutics, Inc. | FORMULATIONS FOR THE TREATMENT OF DRY EYE |
| JP2022511030A (ja) * | 2018-12-05 | 2022-01-28 | アルデイラ セラピューティクス， インコーポレイテッド | 注射可能な製剤 |
| AU2019409160B2 (en) * | 2018-12-18 | 2022-03-24 | Zhuhai United Laboratories Co., Ltd. | Compound for use in retinal diseases |
| US11786518B2 (en) | 2019-03-26 | 2023-10-17 | Aldeyra Therapeutics, Inc. | Ophthalmic formulations and uses thereof |
| US12098132B2 (en) | 2019-05-02 | 2024-09-24 | Aldeyra Therapeutics, Inc. | Process for preparation of aldehyde scavenger and intermediates |
| CN113784954A (zh) | 2019-05-02 | 2021-12-10 | 奥尔德拉医疗公司 | 多晶型化合物和其用途 |
| CA3159453A1 (en) * | 2019-12-30 | 2021-07-08 | Huijun YIN | Tricyclic compound, and preparation method therefor and medical use thereof |
| CA3175856A1 (en) | 2020-05-13 | 2021-11-18 | Todd Brady | Pharmaceutical formulations and uses thereof |
| CN115843293B (zh) * | 2021-06-25 | 2025-01-24 | 中国医药研究开发中心有限公司 | 三环化合物及其制备方法和医药用途 |
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2016
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| CO2018002822A2 (es) | 2018-05-31 |
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| US11046650B2 (en) | 2021-06-29 |
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