CN1185008C - 含有谷胱甘肽类似物的治疗用组合物 - Google Patents

含有谷胱甘肽类似物的治疗用组合物 Download PDF

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Publication number
CN1185008C
CN1185008C CNB008046522A CN00804652A CN1185008C CN 1185008 C CN1185008 C CN 1185008C CN B008046522 A CNB008046522 A CN B008046522A CN 00804652 A CN00804652 A CN 00804652A CN 1185008 C CN1185008 C CN 1185008C
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CN
China
Prior art keywords
lipid
parts
compound
glutamyl
benzyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008046522A
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English (en)
Chinese (zh)
Other versions
CN1342084A (zh
Inventor
托马斯·雷得美尔
劳伦斯·M·卡瓦
罗伯特·T·卢穆
马修·H·利特尔
罗伯特·W·马克撒塔
史蒂文·R·修
胡果·O·维拉
米歇尔·R·柯孜卢斯基
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Telik Inc
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Telik Inc
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Publication of CN1342084A publication Critical patent/CN1342084A/zh
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Publication of CN1185008C publication Critical patent/CN1185008C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CNB008046522A 1999-01-27 2000-01-27 含有谷胱甘肽类似物的治疗用组合物 Expired - Fee Related CN1185008C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23853099A 1999-01-27 1999-01-27
US09/238,530 1999-01-27

Publications (2)

Publication Number Publication Date
CN1342084A CN1342084A (zh) 2002-03-27
CN1185008C true CN1185008C (zh) 2005-01-19

Family

ID=22898312

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008046522A Expired - Fee Related CN1185008C (zh) 1999-01-27 2000-01-27 含有谷胱甘肽类似物的治疗用组合物

Country Status (12)

Country Link
EP (1) EP1143992B1 (https=)
JP (2) JP2002535359A (https=)
KR (1) KR100750842B1 (https=)
CN (1) CN1185008C (https=)
AT (1) ATE286741T1 (https=)
AU (1) AU778340B2 (https=)
CA (1) CA2360795C (https=)
DE (1) DE60017359T2 (https=)
ES (1) ES2231159T3 (https=)
HK (1) HK1043310B (https=)
PT (1) PT1143992E (https=)
WO (1) WO2000044366A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW576838B (en) 1998-04-16 2004-02-21 Teijin Ltd Glutathione derivatives and application form thereof
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
BRPI0606520A2 (pt) * 2005-01-06 2009-06-30 Telik Inc tripeptìdeo e tetrapeptìdeo tioéteres
CN101434645B (zh) * 2008-12-24 2013-01-16 中国农业大学 一种合成寡肽及其用途
AU2012321104A1 (en) * 2011-12-02 2013-06-20 Telik, Inc. Amphorous ezatiostat ansolvate
CN108863888B (zh) * 2018-07-18 2021-10-12 吉尔生化（上海）有限公司 一种(s)-1-(叔丁氧羰基)-5-氧吡咯烷-2-羧酸乙酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
JP3118869B2 (ja) * 1991-05-14 2000-12-18 ウェルファイド株式会社 プロスタグランジン類含有脂肪小体組成物
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
JPH09504517A (ja) * 1993-09-27 1997-05-06 スミスクライン・ビーチャム・コーポレイション カンプトテシン処方物
JP2891883B2 (ja) * 1993-11-05 1999-05-17 学校法人近畿大学 抗白内障医薬組成物
JPH11507056A (ja) * 1995-06-07 1999-06-22 テラピン テクノロジーズ、インク． グルタチオンアナログの代謝的効果

Also Published As

Publication number Publication date
WO2000044366A2 (en) 2000-08-03
ES2231159T3 (es) 2005-05-16
EP1143992A2 (en) 2001-10-17
DE60017359T2 (de) 2005-12-01
KR100750842B1 (ko) 2007-08-22
EP1143992B1 (en) 2005-01-12
ATE286741T1 (de) 2005-01-15
AU778340B2 (en) 2004-12-02
DE60017359D1 (de) 2005-02-17
PT1143992E (pt) 2005-05-31
HK1043310B (zh) 2005-10-07
WO2000044366A3 (en) 2000-12-21
CA2360795A1 (en) 2000-08-03
JP2007326877A (ja) 2007-12-20
AU2976700A (en) 2000-08-18
HK1043310A1 (en) 2002-09-13
CN1342084A (zh) 2002-03-27
JP2002535359A (ja) 2002-10-22
KR20010101775A (ko) 2001-11-14
CA2360795C (en) 2010-03-23

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Granted publication date: 20050119

Termination date: 20140127