JP2002535359A - グルタチオン類縁体を含有する治療用組成物 - Google Patents

グルタチオン類縁体を含有する治療用組成物

Info

Publication number
JP2002535359A
JP2002535359A JP2000595670A JP2000595670A JP2002535359A JP 2002535359 A JP2002535359 A JP 2002535359A JP 2000595670 A JP2000595670 A JP 2000595670A JP 2000595670 A JP2000595670 A JP 2000595670A JP 2002535359 A JP2002535359 A JP 2002535359A
Authority
JP
Japan
Prior art keywords
compound
formula
pharmaceutically acceptable
acceptable salt
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000595670A
Other languages
English (en)
Japanese (ja)
Inventor
トーマス・レデルマイアー
ローレンス・エム・コーバー
ロバート・ティ・ラム
マシュー・エイチ・リトル
ロバート・ダブリュー・マクサタ
スティーブン・アール・ショウ
ヒューゴー・オー・ビラー
マイケル・アール・コズロウスキー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telik Inc
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Publication of JP2002535359A publication Critical patent/JP2002535359A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000595670A 1999-01-27 2000-01-27 グルタチオン類縁体を含有する治療用組成物 Pending JP2002535359A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23853099A 1999-01-27 1999-01-27
US09/238,530 1999-01-27
PCT/US2000/002297 WO2000044366A2 (en) 1999-01-27 2000-01-27 Therapeutic compositions containing glutathione analogs

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007229798A Division JP2007326877A (ja) 1999-01-27 2007-09-05 グルタチオン類縁体を含有する治療用組成物

Publications (1)

Publication Number Publication Date
JP2002535359A true JP2002535359A (ja) 2002-10-22

Family

ID=22898312

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2000595670A Pending JP2002535359A (ja) 1999-01-27 2000-01-27 グルタチオン類縁体を含有する治療用組成物
JP2007229798A Pending JP2007326877A (ja) 1999-01-27 2007-09-05 グルタチオン類縁体を含有する治療用組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007229798A Pending JP2007326877A (ja) 1999-01-27 2007-09-05 グルタチオン類縁体を含有する治療用組成物

Country Status (12)

Country Link
EP (1) EP1143992B1 (https=)
JP (2) JP2002535359A (https=)
KR (1) KR100750842B1 (https=)
CN (1) CN1185008C (https=)
AT (1) ATE286741T1 (https=)
AU (1) AU778340B2 (https=)
CA (1) CA2360795C (https=)
DE (1) DE60017359T2 (https=)
ES (1) ES2231159T3 (https=)
HK (1) HK1043310B (https=)
PT (1) PT1143992E (https=)
WO (1) WO2000044366A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008526880A (ja) * 2005-01-06 2008-07-24 テリック，インコーポレイテッド トリペプチドおよびテトラペプチドスルホン

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW576838B (en) 1998-04-16 2004-02-21 Teijin Ltd Glutathione derivatives and application form thereof
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
CN101434645B (zh) * 2008-12-24 2013-01-16 中国农业大学 一种合成寡肽及其用途
AU2012321104A1 (en) * 2011-12-02 2013-06-20 Telik, Inc. Amphorous ezatiostat ansolvate
CN108863888B (zh) * 2018-07-18 2021-10-12 吉尔生化（上海）有限公司 一种(s)-1-(叔丁氧羰基)-5-氧吡咯烷-2-羧酸乙酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
JP3118869B2 (ja) * 1991-05-14 2000-12-18 ウェルファイド株式会社 プロスタグランジン類含有脂肪小体組成物
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
JPH09504517A (ja) * 1993-09-27 1997-05-06 スミスクライン・ビーチャム・コーポレイション カンプトテシン処方物
JP2891883B2 (ja) * 1993-11-05 1999-05-17 学校法人近畿大学 抗白内障医薬組成物
JPH11507056A (ja) * 1995-06-07 1999-06-22 テラピン テクノロジーズ、インク． グルタチオンアナログの代謝的効果

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008526880A (ja) * 2005-01-06 2008-07-24 テリック，インコーポレイテッド トリペプチドおよびテトラペプチドスルホン
JP2008526859A (ja) * 2005-01-06 2008-07-24 テリック，インコーポレイテッド トリペプチドおよびテトラペプチドチオエーテル

Also Published As

Publication number Publication date
WO2000044366A2 (en) 2000-08-03
ES2231159T3 (es) 2005-05-16
EP1143992A2 (en) 2001-10-17
DE60017359T2 (de) 2005-12-01
KR100750842B1 (ko) 2007-08-22
EP1143992B1 (en) 2005-01-12
ATE286741T1 (de) 2005-01-15
AU778340B2 (en) 2004-12-02
CN1185008C (zh) 2005-01-19
DE60017359D1 (de) 2005-02-17
PT1143992E (pt) 2005-05-31
HK1043310B (zh) 2005-10-07
WO2000044366A3 (en) 2000-12-21
CA2360795A1 (en) 2000-08-03
JP2007326877A (ja) 2007-12-20
AU2976700A (en) 2000-08-18
HK1043310A1 (en) 2002-09-13
CN1342084A (zh) 2002-03-27
KR20010101775A (ko) 2001-11-14
CA2360795C (en) 2010-03-23

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