DE60017359T2 - Glutathioneanaloge enthaltende therapeutische zusammensetzungen - Google Patents

Glutathioneanaloge enthaltende therapeutische zusammensetzungen Download PDF

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Publication number
DE60017359T2
DE60017359T2 DE60017359T DE60017359T DE60017359T2 DE 60017359 T2 DE60017359 T2 DE 60017359T2 DE 60017359 T DE60017359 T DE 60017359T DE 60017359 T DE60017359 T DE 60017359T DE 60017359 T2 DE60017359 T2 DE 60017359T2
Authority
DE
Germany
Prior art keywords
compound
lipid
lipid formulation
weight
parts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60017359T
Other languages
German (de)
English (en)
Other versions
DE60017359D1 (de
Inventor
Thomas Redelmeier
M. Lawrence KAUVAR
T. Robert LUM
H. Matthew LYTTLE
W. Robert MACSATA
R. Steven SCHOW
O. Hugo VILLAR
R. Michael KOZLOWSKI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Telik Inc
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Application granted granted Critical
Publication of DE60017359D1 publication Critical patent/DE60017359D1/de
Publication of DE60017359T2 publication Critical patent/DE60017359T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A61K38/063—Glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60017359T 1999-01-27 2000-01-27 Glutathioneanaloge enthaltende therapeutische zusammensetzungen Expired - Lifetime DE60017359T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23853099A 1999-01-27 1999-01-27
US238530 1999-01-27
PCT/US2000/002297 WO2000044366A2 (en) 1999-01-27 2000-01-27 Therapeutic compositions containing glutathione analogs

Publications (2)

Publication Number Publication Date
DE60017359D1 DE60017359D1 (de) 2005-02-17
DE60017359T2 true DE60017359T2 (de) 2005-12-01

Family

ID=22898312

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60017359T Expired - Lifetime DE60017359T2 (de) 1999-01-27 2000-01-27 Glutathioneanaloge enthaltende therapeutische zusammensetzungen

Country Status (12)

Country Link
EP (1) EP1143992B1 (https=)
JP (2) JP2002535359A (https=)
KR (1) KR100750842B1 (https=)
CN (1) CN1185008C (https=)
AT (1) ATE286741T1 (https=)
AU (1) AU778340B2 (https=)
CA (1) CA2360795C (https=)
DE (1) DE60017359T2 (https=)
ES (1) ES2231159T3 (https=)
HK (1) HK1043310B (https=)
PT (1) PT1143992E (https=)
WO (1) WO2000044366A2 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW576838B (en) 1998-04-16 2004-02-21 Teijin Ltd Glutathione derivatives and application form thereof
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
BRPI0606520A2 (pt) * 2005-01-06 2009-06-30 Telik Inc tripeptìdeo e tetrapeptìdeo tioéteres
CN101434645B (zh) * 2008-12-24 2013-01-16 中国农业大学 一种合成寡肽及其用途
AU2012321104A1 (en) * 2011-12-02 2013-06-20 Telik, Inc. Amphorous ezatiostat ansolvate
CN108863888B (zh) * 2018-07-18 2021-10-12 吉尔生化（上海）有限公司 一种(s)-1-(叔丁氧羰基)-5-氧吡咯烷-2-羧酸乙酯的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
JP3118869B2 (ja) * 1991-05-14 2000-12-18 ウェルファイド株式会社 プロスタグランジン類含有脂肪小体組成物
CA2087902C (en) * 1992-02-05 2006-10-17 Narendra Raghunathji Desai Liposome compositions of porphyrin photosensitizers
JP3383704B2 (ja) * 1993-04-02 2003-03-04 わかもと製薬株式会社 安定なリポソーム水分散液
JPH09504517A (ja) * 1993-09-27 1997-05-06 スミスクライン・ビーチャム・コーポレイション カンプトテシン処方物
JP2891883B2 (ja) * 1993-11-05 1999-05-17 学校法人近畿大学 抗白内障医薬組成物
JPH11507056A (ja) * 1995-06-07 1999-06-22 テラピン テクノロジーズ、インク． グルタチオンアナログの代謝的効果

Also Published As

Publication number Publication date
WO2000044366A2 (en) 2000-08-03
ES2231159T3 (es) 2005-05-16
EP1143992A2 (en) 2001-10-17
KR100750842B1 (ko) 2007-08-22
EP1143992B1 (en) 2005-01-12
ATE286741T1 (de) 2005-01-15
AU778340B2 (en) 2004-12-02
CN1185008C (zh) 2005-01-19
DE60017359D1 (de) 2005-02-17
PT1143992E (pt) 2005-05-31
HK1043310B (zh) 2005-10-07
WO2000044366A3 (en) 2000-12-21
CA2360795A1 (en) 2000-08-03
JP2007326877A (ja) 2007-12-20
AU2976700A (en) 2000-08-18
HK1043310A1 (en) 2002-09-13
CN1342084A (zh) 2002-03-27
JP2002535359A (ja) 2002-10-22
KR20010101775A (ko) 2001-11-14
CA2360795C (en) 2010-03-23

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