CN1167811C - 酶原性核酸的检测方法,以及相关分子和试剂盒 - Google Patents

酶原性核酸的检测方法,以及相关分子和试剂盒 Download PDF

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CN1167811C
CN1167811C CNB998111147A CN99811114A CN1167811C CN 1167811 C CN1167811 C CN 1167811C CN B998111147 A CNB998111147 A CN B998111147A CN 99811114 A CN99811114 A CN 99811114A CN 1167811 C CN1167811 C CN 1167811C
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nucleic acid
target
primer
sample
dna
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CN1319142A (zh
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A���е�
A·托德
C·J·富尔里
M·凯恩斯
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Johnson and Johnson Research Pty Ltd
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6823—Release of bound markers
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6867—Replicase-based amplification, e.g. using Q-beta replicase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
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  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB998111147A 1998-03-05 1999-02-22 酶原性核酸的检测方法,以及相关分子和试剂盒 Expired - Fee Related CN1167811C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7689998P 1998-03-05 1998-03-05
US60/076,899 1998-03-05

Publications (2)

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CN1319142A CN1319142A (zh) 2001-10-24
CN1167811C true CN1167811C (zh) 2004-09-22

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US (3) US6140055A (https=)
EP (1) EP1062367B1 (https=)
JP (1) JP4318856B2 (https=)
KR (1) KR100748863B1 (https=)
CN (1) CN1167811C (https=)
AT (1) ATE414169T1 (https=)
AU (1) AU768627B2 (https=)
BR (1) BR9908567A (https=)
CA (1) CA2321948A1 (https=)
DE (1) DE69939896D1 (https=)
IL (2) IL164182A0 (https=)
WO (1) WO1999045146A1 (https=)
ZA (1) ZA991772B (https=)

Cited By (1)

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CN103013953A (zh) * 2012-10-19 2013-04-03 中国科学院成都生物研究所 一种剪切dna的dna酶

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US7205129B1 (en) * 2000-02-28 2007-04-17 Qiagen Gmbh Method for reducing artifacts in nucleic acid amplification
US20030104520A1 (en) * 2000-06-15 2003-06-05 Ellington Andrew D. Regulatable, catalytically active nucleic acids
US7125660B2 (en) 2000-09-13 2006-10-24 Archemix Corp. Nucleic acid sensor molecules and methods of using same
WO2003014375A2 (en) * 2001-08-09 2003-02-20 Archemix Corporation Nucleic acid sensor molecules and methods of using same
US7297485B2 (en) * 2001-10-15 2007-11-20 Qiagen Gmbh Method for nucleic acid amplification that results in low amplification bias
US6617137B2 (en) * 2001-10-15 2003-09-09 Molecular Staging Inc. Method of amplifying whole genomes without subjecting the genome to denaturing conditions
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US7955795B2 (en) * 2003-06-06 2011-06-07 Qiagen Gmbh Method of whole genome amplification with reduced artifact production
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103013953A (zh) * 2012-10-19 2013-04-03 中国科学院成都生物研究所 一种剪切dna的dna酶
CN103013953B (zh) * 2012-10-19 2014-09-17 中国科学院成都生物研究所 一种剪切dna的dna酶

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CA2321948A1 (en) 1999-09-10
AU768627B2 (en) 2003-12-18
EP1062367A1 (en) 2000-12-27
WO1999045146A1 (en) 1999-09-10
JP2002505117A (ja) 2002-02-19
EP1062367B1 (en) 2008-11-12
AU3340999A (en) 1999-09-20
DE69939896D1 (de) 2008-12-24
US20010001063A1 (en) 2001-05-10
ZA991772B (en) 2000-10-12
BR9908567A (pt) 2000-12-12
US6365724B2 (en) 2002-04-02
JP4318856B2 (ja) 2009-08-26
IL164182A0 (en) 2005-12-18
IL138126A0 (en) 2001-10-31
CN1319142A (zh) 2001-10-24
US6140055A (en) 2000-10-31
ATE414169T1 (de) 2008-11-15
KR20010041591A (ko) 2001-05-25
EP1062367A4 (en) 2003-07-30
US6201113B1 (en) 2001-03-13
KR100748863B1 (ko) 2007-08-13

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