CN1161469C - 在细胞培养中增强干扰素生产的方法 - Google Patents

在细胞培养中增强干扰素生产的方法 Download PDF

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CN1161469C
CN1161469C CNB961977515A CN96197751A CN1161469C CN 1161469 C CN1161469 C CN 1161469C CN B961977515 A CNB961977515 A CN B961977515A CN 96197751 A CN96197751 A CN 96197751A CN 1161469 C CN1161469 C CN 1161469C
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interferon
cells
pkr
alpha
progeny
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CN1200148A (zh
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S
阿兰·S·劳
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University of California San Diego UCSD
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    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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    • C07K14/52—Cytokines; Lymphokines; Interferons
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/67—General methods for enhancing the expression
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • A—HUMAN NECESSITIES
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2310/11—Antisense
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    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
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    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32051—Methods of production or purification of viral material

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  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB961977515A 1995-08-22 1996-08-22 在细胞培养中增强干扰素生产的方法 Expired - Fee Related CN1161469C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US262195P 1995-08-22 1995-08-22
US60/002,621 1995-08-22

Publications (2)

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CN1200148A CN1200148A (zh) 1998-11-25
CN1161469C true CN1161469C (zh) 2004-08-11

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CNB961977515A Expired - Fee Related CN1161469C (zh) 1995-08-22 1996-08-22 在细胞培养中增强干扰素生产的方法

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US (6) US5840565A (https=)
EP (2) EP0846160B1 (https=)
JP (2) JP4267693B2 (https=)
CN (1) CN1161469C (https=)
AT (1) ATE289348T1 (https=)
AU (2) AU707130B2 (https=)
BR (1) BR9610550A (https=)
CA (2) CA2229163C (https=)
DE (1) DE69634360T2 (https=)
WO (2) WO1997008292A1 (https=)

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Publication number Publication date
US6159712A (en) 2000-12-12
JPH11514344A (ja) 1999-12-07
US20010001290A1 (en) 2001-05-17
US20010001709A1 (en) 2001-05-24
US5840565A (en) 1998-11-24
EP0846174A1 (en) 1998-06-10
JP3432519B2 (ja) 2003-08-04
CA2229163A1 (en) 1997-03-06
EP0846160B1 (en) 2005-02-16
US7132271B2 (en) 2006-11-07
DE69634360D1 (de) 2005-03-24
EP0846160A4 (en) 2002-01-02
CA2229405A1 (en) 1997-03-06
US6489144B1 (en) 2002-12-03
MX9801423A (es) 1998-05-31
AU6860896A (en) 1997-03-19
WO1997008324A1 (en) 1997-03-06
CA2229405C (en) 2004-03-02
DE69634360T2 (de) 2005-12-29
US20040157310A1 (en) 2004-08-12
EP0846160A1 (en) 1998-06-10
AU6857696A (en) 1997-03-19
CN1200148A (zh) 1998-11-25
US6673591B2 (en) 2004-01-06
JPH11511324A (ja) 1999-10-05
BR9610550A (pt) 1999-07-06
CA2229163C (en) 2011-04-05
EP0846174A4 (en) 2003-02-05
JP4267693B2 (ja) 2009-05-27
WO1997008292A1 (en) 1997-03-06
ATE289348T1 (de) 2005-03-15
AU707130B2 (en) 1999-07-01
US6686190B2 (en) 2004-02-03

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